keyword
https://read.qxmd.com/read/38576825/immunovirological-status-in-people-with-perinatal-and-adult-acquired-hiv-1-infection-a-multi-cohort-analysis-from-france
#21
JOURNAL ARTICLE
Rémonie Seng, Pierre Frange, Albert Faye, Catherine Dollfus, Jérôme le Chenadec, Faroudy Boufassa, Asma Essat, Tessa Goetghebuer, Elisa Arezes, Véronique Avettand-Fènoël, Jean-Joël Bigna, Stéphane Blanche, Cécile Goujard, Laurence Meyer, Josiane Warszawski, Jean-Paul Viard
BACKGROUND: No study has compared the virological and immunological status of young people with perinatally-acquired HIV infection (P-HIV) with that of people with HIV adulthood (A-HIV) having a similar duration of infection. METHODS: 5 French cohorts of P-HIV and A-HIV patients with a known date of HIV-infection and receiving antiretroviral treatment (ART), were used to compare the following proportions of: virological failure (VF) defined as plasma HIV RNA ≥ 50 copies/mL, CD4 cell percentages and CD4:CD8 ratios, at the time of the most recent visit since 2012...
May 2024: The Lancet regional health. Europe
https://read.qxmd.com/read/38574664/a-powerful-method-for-in-situ-and-rapid-detection-of-trace-nanoplastics-in-water-mie-scattering
#22
JOURNAL ARTICLE
Lei Mou, Qinzhou Zhang, Ruilong Li, Yaxian Zhu, Yong Zhang
The pervasive presence of nanoplastics (NPs) in environmental media has raised significant concerns regarding their implications for environmental safety and human health. However, owing to their tiny size and low level in the environment, there is still a lack of effective methods for measuring the amount of NPs. Leveraging the principles of Mie scattering, a novel approach for rapid in situ quantitative detection of small NPs in low concentrations in water has been developed. A limit of detection of 4.2 μg/L for in situ quantitative detection of polystyrene microspheres as small as 25 nm was achieved, and satisfactory recoveries and relative standard deviations were obtained...
April 1, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38574596/moral-injury-race-related-stress-and-post-traumatic-stress-disorder-in-a-trauma-exposed-black-population
#23
JOURNAL ARTICLE
Aziz Elbasheir, Travis M Fulton, Khaled C Choucair, Emma C Lathan, Briana N Spivey, Alfonsina Guelfo, Sierra E Carter, Abigail Powers, Negar Fani
BACKGROUND: Race-related stress (RRS) is an unrecognized source of moral injury (MI)-or the emotional and/or spiritual suffering that may emerge after exposure to events that violate deeply held beliefs. Additionally, MI has not been explored as a mechanism of risk for post-traumatic stress disorder (PTSD) in trauma-exposed civilians. We examined relations among exposure to potentially morally injurious events (moral injury exposure, MIE), related distress (moral injury distress, MID), and RRS in Black Americans...
March 16, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38573458/-there-is-still-a-part-of-me-that-would-love-to-be-the-old-me-again-how-do-adolescents-and-young-adults-aya-experience-cancer-related-bodily-changes-a-phenomenological-interview-study
#24
JOURNAL ARTICLE
Robin T J Hendriks, Mies C H J van Eenbergen, Marjolein L de Boer, Sophia H E Sleeman, Dorry Boll, Olga Husson, Tom I Bootsma
PURPOSE: Due to the increase in both cancer incidence and overall survival rates, more adolescents and young adults (AYAs) have to live with the effects that their cancer diagnosis and following treatments have on their bodies. This qualitative phenomenological study aimed to gain more insight into the way AYAs experience these effects and how they respond to these effects. METHODS: Semi-structured interviews with a sample of 11 AYAs with an age range of 25-41 years at the time of the interview, who were diagnosed with different types of cancer, were conducted...
April 4, 2024: Journal of Cancer Survivorship: Research and Practice
https://read.qxmd.com/read/38572261/poor-sleep-quality-and-its-associated-factors-among-working-adults-during-covid-19-pandemic-in-malaysia
#25
JOURNAL ARTICLE
Lwin Mie Aye, Wei Hao Lee
BACKGROUND: In Malaysia, a nationwide movement control order (MCO), implemented to curb the COVID-19 spread, impacted on the lives of the working population which could impair sleep quality. OBJECTIVE: This study aims to find the sleep quality status and its association with the socioeconomic, employment and lifestyle factors of working adults during the MCO period. METHODS: A cross-sectional study was conducted among 500 eligible working adults...
2024: Global Mental Health
https://read.qxmd.com/read/38571274/scattering-of-partially-coherent-electromagnetic-beams-by-a-sphere
#26
JOURNAL ARTICLE
Hugo F Schouten, Taco D Visser
We examine the scattering of a partially coherent, partially polarized electromagnetic beam by a homogeneous sphere (Mie scattering). The degree of polarization and the Stokes parameters in the far zone are found to be strongly dependent on the state of coherence and polarization of the incident beam. In particular, we demonstrate the emergence of polarization singularities and show that partial spatial coherence gives rise to significant depolarization effects. In addition we explore the symmetry properties of the scattered field...
March 11, 2024: Optics Express
https://read.qxmd.com/read/38571206/continuous-wave-terahertz-detection-using-1550%C3%A2-nm-pumped-nonlinear-photoconductive-gaas-metasurfaces
#27
JOURNAL ARTICLE
James Seddon, Lucy Hale, Hyunseung Jung, Sarah Norman, Igal Brener, Alwyn Seeds, Cyril Renaud, Oleg Mitrofanov
Terahertz (THz) continuous wave (CW) spectroscopy systems can offer extremely high spectral resolution over the THz band by photo-mixing high-performance telecommunications-band (1530-1565 nm) lasers. However, typical THz CW detectors in these systems use narrow band-gap photoconductors, which require elaborate material growth and generate relatively large detector noise. Here we demonstrate that two-step photon absorption in a nano-structured low-temperature grown GaAs (LT-GaAs) metasurface which enables switching of photoconductivity within approximately one picosecond...
March 11, 2024: Optics Express
https://read.qxmd.com/read/38571171/response-of-mineral-particles-in-inland-lakes-to-water-optical-properties-and-its-influence-on-chlorophyll-a-estimation
#28
JOURNAL ARTICLE
Huaiqing Liu, Chenyang Wei, Heng Lyu, Song Miao, Yunmei Li, Honglei Guo, Xianzhang Dong, Fangfang Chen, Yuxin Zhu
Many chlorophyll-a (Chl-a) remote sensing estimation algorithms have been developed for inland water, and they are proposed always based on some ideal assumptions, which are difficult to meet in complex inland waters. Based on MIE scattering theory, this study calculated the optical properties of mineral particles under different size distribution and refractive index conditions, and the Hydrolight software was employed to simulate remote sensing reflectance in the presence of different mineral particles. The findings indicated that the reflectance is significantly influenced by the slope (j) of particle size distribution function and the imaginary part (n') of the refractive index, with the real part (n) having a comparatively minor impact...
March 11, 2024: Optics Express
https://read.qxmd.com/read/38571046/variability-in-the-relationship-between-light-scattering-and-chlorophyll-a-concentration-in-oligotrophic-tropical-regions-of-the-western-pacific-ocean
#29
JOURNAL ARTICLE
Yanxia Liu, Yunwei Li, Liwen Yan, Zehua Zhang, Haibo Bi, Haijun Huang
It is important to determine the relationship between the concentration of chlorophyll a (Chla) and the inherent optical properties (IOPs) of ocean water to develop optical models and algorithms that characterize the biogeochemical properties and estimate biological pumping and carbon flux in this environment. However, previous studies reported relatively large variations in the particulate backscattering coefficient (bbp (λ)) and Chla from more eutrophic high-latitude waters to clear oligotrophic waters, especially in oligotrophic oceanic areas where these two variables have little covariation...
March 25, 2024: Optics Express
https://read.qxmd.com/read/38571006/computational-modeling-of-chlamydomonas-reinhardtii-cellular-radiation-properties-with-synergistic-consideration-of-complex-structures-and-compositions
#30
JOURNAL ARTICLE
Li Lin, Miao Jiang, Xingcan Li, Jia-Yue Yang
The radiation characteristics of microalgae are of great significance for the design of photobioreactors and ocean optical remote sensing. Yet the complex structure of microalgae makes it difficult to theoretically predict its radiation characteristics based on traditional Mie theory. In this work, taking Chlamydomonas reinhardtii as an example, a multi-component cell model with a complex structure is proposed, which considers the organelles and shape of microalgae, and the volume change during the production of Chlamydomonas reinhardtii lipids...
March 25, 2024: Optics Express
https://read.qxmd.com/read/38569873/prognostic-factors-for-disease-activity-in-newly-diagnosed-teriflunomide-treated-patients-with-multiple-sclerosis-a-nationwide-danish-study
#31
JOURNAL ARTICLE
Mie Reith Mahler, Melinda Magyari, Luigi Pontieri, Frederik Elberling, Rolf Pringler Holm, Arkadiusz Weglewski, Mai Bang Poulsen, Lars Kristian Storr, Plamen Anzhelov Bekyarov, Zsolt Illes, Matthias Kant, Tobias Sejbaek, Morten Leif Stilund, Peter V Rasmussen, Maria Brask, Inga Urbonaviciute, Finn Sellebjerg
BACKGROUND: Clinicians frequently rely on relapse counts, T2 MRI lesion load (T2L) and Expanded Disability Status Scale (EDSS) scores to guide treatment decisions for individuals diagnosed with multiple sclerosis (MS). This study evaluates how these factors, along with age and sex, influence prognosis during treatment with teriflunomide (TFL). METHODS: We conducted a nationwide cohort study using data from the Danish Multiple Sclerosis Registry.Eligible participants had relapsing-remitting MS or clinically isolated syndrome and initiated TFL as their first treatment between 2013 and 2019...
April 3, 2024: Journal of Neurology, Neurosurgery, and Psychiatry
https://read.qxmd.com/read/38568924/maternal-outcomes-of-planned-mode-of-delivery-for-term-breech-in-nulliparous-women
#32
JOURNAL ARTICLE
Malene Mie Caning, Steen Christian Rasmussen, Lone Krebs
OBJECTIVE: To estimate short- and long-term maternal complications in relation to planned mode of term breech delivery in first pregnancy. DESIGN: Register-based cohort study. SETTING: Denmark. POPULATION: Nulliparous women with singleton breech delivery at term between 1991 and 2018 (n = 30,778). METHODS: We used data from the Danish national health registries to identify nulliparous women with singleton breech presentation at term and their subsequent pregnancies...
2024: PloS One
https://read.qxmd.com/read/38568595/description-and-reconstruction-of-typical-structured-light-beams-with-vector-spherical-wave-functions
#33
JOURNAL ARTICLE
Yiyu Shi, Zhiwei Cui, Zhanfei Liu, Shuaishuai Ren, Fuping Wu
It is well known that the generalized Lorenz-Mie theory (GLMT) is a rigorous analytical method for dealing with the interaction between light beams and spherical particles, which involves the description and reconstruction of the light beams with vector spherical wave functions (VSWFs). In this paper, a detailed study on the description and reconstruction of the typical structured light beams with VSWFs is reported. We first systematically derive the so-called beam shape coefficients (BSCs) of typical structured light beams, including the fundamental Gaussian beam, Hermite-Gaussian beam, Laguerre-Gaussian beam, Bessel beam, and Airy beam, with the aid of the angular spectrum decomposition method...
March 20, 2024: Applied Optics
https://read.qxmd.com/read/38568512/optical-pulling-force-on-a-uniaxial-anisotropic-sphere-by-a-high-order-bessel-vortex-beam
#34
JOURNAL ARTICLE
Zheng Jun Li
Based on the generalized Lorenz-Mie theory (GLMT) and the scattering theory of uniaxial spheres, a theoretical approach is introduced to study the axial radiation force (AOF) exerted on a uniaxial anisotropic sphere illuminated by an on-axis high-order Bessel (vortex) beams (HOBVBs). Applying Maxwell's stress tensor, an analytical expression of the AOF on a uniaxial anisotropic sphere by the on-axis HOBVB is derived. The correctness of the theoretical and numerical results is verified by comparing the AOF on an isotropic sphere by a zero-order Bessel beam (ZOBB) with those results by a plane wave, Gaussian beam, and ZOBB...
April 1, 2024: Applied Optics
https://read.qxmd.com/read/38567229/perceptions-of-uncertainty-in-medical-care-among-non-medical-professionals-and-nurses-in-japan-a-cross-sectional-internet-based-preliminary-survey
#35
JOURNAL ARTICLE
Naomi Akiyama, Shihoko Kajiwara, Ryuji Uozumi, Tomoya Akiyama, Kenshi Hayashida, Jasmine Sim, Mie Morikawa
BACKGROUND: Medical care is impacted by uncertainty caused by various factors. The uncertainty that exists in medical care can cause patient distrust and lead to conflict. This study compared the tolerance of uncertainty in medical care between non-medical professionals and nurses. METHODS: We conducted a cross-sectional Internet-based survey. Participants included 2,100 individuals (600 nurses and 1,500 non-medical professionals; aged ≥ 20 years) from different parts of Japan...
March 2024: Curēus
https://read.qxmd.com/read/38563382/enantiomer-specific-cardiovascular-effects-of-the-ketone-body-3-hydroxybutyrate
#36
JOURNAL ARTICLE
Nigopan Gopalasingam, Niels Moeslund, Kristian Hylleberg Christensen, Kristoffer Berg-Hansen, Jacob Seefeldt, Casper Homilius, Erik Nguyen Nielsen, Mie Ringgaard Dollerup, Aage K Alstrup Olsen, Mogens Johannsen, Ebbe Boedtkjer, Niels Møller, Hans Eiskjær, Lars Christian Gormsen, Roni Nielsen, Henrik Wiggers
BACKGROUND: The ketone body 3-hydroxybutyrate (3-OHB) increases cardiac output (CO) by 35% to 40% in healthy people and people with heart failure. The mechanisms underlying the effects of 3-OHB on myocardial contractility and loading conditions as well as the cardiovascular effects of its enantiomeric forms, D-3-OHB and L-3-OHB, remain undetermined. METHODS AND RESULTS: Three groups of 8 pigs each underwent a randomized, crossover study. The groups received 3-hour infusions of either D/L-3-OHB (racemic mixture), 100% L-3-OHB, 100% D-3-OHB, versus an isovolumic control...
April 2, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38563088/an-exploration-of-the-genetics-of-the-mutant-huntingtin-mhtt-gene-in-a-cohort-of-patients-with-chorea-from-different-ethnic-groups-in-sub-saharan-africa
#37
JOURNAL ARTICLE
Mendi J Muthinja, Carlos Othon Guelngar, Maouly Fall, Fatumah Jama, Huda Aldeen Shuja, Jamila Nambafu, Daniel Gams Massi, Oluwadamilola O Ojo, Njideka U Okubadejo, Funmilola Tolulope Taiwo, Alassane Mamadou Diop, Coudjou J D G de Chacus, Fodé Abass Cissé, Amara Cissé, Juzar Hooker, Dilraj Sokhi, Henry Houlden, Mie Rizig
BACKGROUND: Africans are underrepresented in Huntington's disease (HD) research. A European ancestor was postulated to have introduced the mutant Huntingtin (mHtt) gene to the continent; however, recent work has shown the existence of a unique Htt haplotype in South-Africa specific to indigenous Africans. OBJECTIVE: We aimed to investigate the CAG trinucleotide repeats expansion in the Htt gene in a geographically diverse cohort of patients with chorea and unaffected controls from sub-Saharan Africa...
April 2, 2024: Annals of Human Genetics
https://read.qxmd.com/read/38562841/genome-wide-analyses-identify-21-infertility-loci-and-over-400-reproductive-hormone-loci-across-the-allele-frequency-spectrum
#38
Samvida S Venkatesh, Laura B L Wittemans, Duncan S Palmer, Nikolas A Baya, Teresa Ferreira, Barney Hill, Frederik Heymann Lassen, Melody J Parker, Saskia Reibe, Ahmed Elhakeem, Karina Banasik, Mie T Bruun, Christian Erikstrup, Bitten A Jensen, Anders Juul, Christina Mikkelsen, Henriette S Nielsen, Sisse R Ostrowski, Ole B Pedersen, Palle D Rohde, Erik Sorensen, Henrik Ullum, David Westergaard, Asgeir Haraldsson, Hilma Holm, Ingileif Jonsdottir, Isleifur Olafsson, Thora Steingrimsdottir, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Jessica Figueredo, Minna K Karjalainen, Anu Pasanen, Benjamin M Jacobs, Nikki Hubers, Margaret Lippincott, Abigail Fraser, Deborah A Lawlor, Nicholas J Timpson, Mette Nyegaard, Kari Stefansson, Reedik Magi, Hannele Laivuori, David A van Heel, Dorret I Boomsma, Ravikumar Balasubramanian, Stephanie B Seminara, Yee-Ming Chan, Triin Laisk, Cecilia M Lindgren
Genome-wide association studies (GWASs) may help inform treatments for infertility, whose causes remain unknown in many cases. Here we present GWAS meta-analyses across six cohorts for male and female infertility in up to 41,200 cases and 687,005 controls. We identified 21 genetic risk loci for infertility ( P ≤5E-08), of which 12 have not been reported for any reproductive condition. We found positive genetic correlations between endometriosis and all-cause female infertility ( r g =0.585, P =8.98E-14), and between polycystic ovary syndrome and anovulatory infertility ( r g =0...
March 20, 2024: medRxiv
https://read.qxmd.com/read/38562108/truncating-variants-of-the-sterol-recognition-region-of-shh-cause-hypertelorism-phenotype-rather-than-hypotelorism-holoprosencephaly
#39
Mamiko Yamada, Seiji Mizuno, Mie Inaba, Tomoko Uehara, Hidehito Inagaki, Hisato Suzuki, Fuyuki Miya, Toshiki Takenouchi, Hiroki Kurahashi, Kenjiro Kosaki
Sonic hedgehog signaling molecule (SHH) is a key molecule in the cilia-mediated signaling pathway and a critical morphogen in embryogenesis. The association between loss-of-function variants of SHH and holoprosencephaly is well established. In mice experiments, reduced or increased signaling of SHH have been shown to be associated with narrowing or excessive expansion of the facial midline, respectively. Herein, we report two unrelated patients with de novo truncating variants of SHH presenting with hypertelorism rather than hypotelorism...
April 2, 2024: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/38560726/fabrication-of-mie-resonant-silicon-nanoparticles-using-laser-annealing-for-surface-enhanced-fluorescence-spectroscopy
#40
JOURNAL ARTICLE
Tatsuya Fukuta, Ryo Kato, Takuo Tanaka, Taka-Aki Yano
Silicon nanostructures with unique Mie resonances have garnered considerable attention in the field of nanophotonics. Here, we present a simple and efficient method for the fabrication of silicon (Si) nanoparticle substrates using continuous-wave (CW) laser annealing. The resulting silicon nanoparticles exhibit Mie resonances in the visible region, and their resonant wavelengths can be precisely controlled. Notably, laser-annealed silicon nanoparticle substrates show a 60-fold enhancement in fluorescence. This tunable and fluorescence-enhancing silicon nanoparticle platform has tremendous potential for highly sensitive fluorescence sensing and biomedical imaging applications...
2024: Microsystems & Nanoengineering
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