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https://www.readbyqxmd.com/read/28644673/limitations-of-particle-based-spasers
#1
Günter Kewes, Kathrin Herrmann, Rogelio Rodríguez-Oliveros, Alexander Kuhlicke, Oliver Benson, Kurt Busch
We present a semiclassical analytic model for spherical core-shell surface plasmon lasers. Within this model, we drop the widely used one-mode approximations in favor of fully electromagnetic Mie theory. This allows for incorporation of realistic gain relaxation rates that so far are massively underestimated. Especially, higher order modes can undermine and even reverse the beneficial effects of the strong Purcell effect in such systems. Our model gives a clear view on gain and resonator requirements, as well as on the output characteristics that will help experimenters to design more efficient particle-based spasers...
June 9, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28643772/cryptic-indole-hydroxylation-by-a-non-canonical-terpenoid-cyclase-parallels-bacterial-xenobiotic-detoxification
#2
Susann Kugel, Martin Baunach, Philipp Baer, Mie Ishida-Ito, Srividhya Sundaram, Zhongli Xu, Michael Groll, Christian Hertweck
Terpenoid natural products comprise a wide range of molecular architectures that typically result from C-C bond formations catalysed by classical type I/II terpene cyclases. However, the molecular diversity of biologically active terpenoids is substantially increased by fully unrelated, non-canonical terpenoid cyclases. Their evolutionary origin has remained enigmatic. Here we report the in vitro reconstitution of an unusual flavin-dependent bacterial indoloterpenoid cyclase, XiaF, together with a designated flavoenzyme-reductase (XiaP) that mediates a key step in xiamycin biosynthesis...
June 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28643075/a-standardized-comparison-of-peri-operative-complications-after-minimally-invasive-esophagectomy-ivor-lewis-versus-mckeown
#3
Andrew M Brown, Michael J Pucci, Adam C Berger, Talar Tatarian, Nathaniel R Evans, Ernest L Rosato, Francesco Palazzo
BACKGROUND: While our institutional approach to esophageal resection for cancer has traditionally favored a minimally invasive (MI) 3-hole, McKeown esophagectomy (MIE 3-hole) during the last five years several factors has determined a shift in our practice with an increasing number of minimally invasive Ivor Lewis (MIE IL) resections being performed. We compared peri-operative outcomes of the two procedures, hypothesizing that MIE IL would be less morbid in the peri-operative setting compared to MIE 3-hole...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28641418/measuring-the-carrier-dynamics-of-photocatalyst-micrograins-using-the-christiansen-effect
#4
Gangbei Zhu, Wei Lu, Jiangrui Zhu, Yunliang Li, Liwei Guo, Yuxiang Weng
The optical measurement of photocatalyst materials is subject to Mie scattering when the particle size is comparable to the wavelength of the probe light. A novel approach was developed to deal with this scattering problem in the transient spectroscopy of photocatalyst micrograins using the Christiansen effect because the probe light in the vicinity of the Christiansen frequency can be transmitted. Scattering theory was used to analyze the transient spectra of micrograins and estimate the extinction coefficient at the Christiansen frequency...
June 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28637993/association-between-excessive-alcohol-use-and-alcohol-related-injuries-in-college-students-a-multi-center-cross-sectional-study-in-japan
#5
Hisashi Yoshimoto, Ayumi Takayashiki, Ryohei Goto, Go Saito, Kyoko Kawaida, Rika Hieda, Yoshihiro Kataoka, Maie Aramaki, Naoto Sakamoto, Tetsuhiro Maeno, Yoshinao Kobayashi, Yousuke C Takemura
Alcohol-related injuries in college students are a major public health problem worldwide. We clarified the association between excessive drinking and alcohol-related injuries in Japanese college students. This was a cross-sectional study with a self-administered questionnaire. From January to March 2013, we sampled all college students and graduate students aged 20 years or older during annual health examinations at three colleges in Mie Prefecture in Japan. The questionnaire assessed the frequency of alcohol drinking, amount of alcohol consumed per day, binge drinking during the past year, alcohol-related injuries during the past year, and demographic data...
2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28636829/analysis-of-minimally-invasive-esophagectomy-at-a-single-veterans-affairs-medical-center
#6
Matthew D Skancke, Robert A Grossman, Gustavo Marino, Fredrick J Brody, Gregory D Trachiotis
BACKGROUND: To date, there are no published studies focusing on the benefits of minimally invasive esophagectomy (MIE) versus open esophagectomy at a Veterans Affairs Medical Center (VAMC). Our primary outcome was the incidence of esophageal malignancy in the veteran population and the postoperative morbidity following traditional and MIE for malignancy. DESIGN: Retrospective analysis of the incidence of esophageal malignancy at a Veteran Integrated Service Network (VISN) 5 VAMC reported to the VAMC Esophageal Tumor Registry between 2003 and 2016 and outcomes of the veterans who received esophagectomy for malignancy...
June 21, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28633912/life-cycle-assessment-and-life-cycle-costs-for-pre-disaster-waste-management-systems
#7
Yohei Wakabayashi, Tsai Peii, Tomohiro Tabata, Takashi Saeki
This study develops a method of environmental and economic evaluation of an integrated disaster waste management system that considers the spatial scale of removal, transport, and treatment of disaster waste. A case study was conducted on combustibles, which is a type of disaster waste derived from dwellings, in Mie Prefecture, Japan. First, we calculated the quantity and the spatial distribution of disaster waste derived from dwellings and tsunami debris produced as a result of a large-scale earthquake. The quantity of disaster waste was estimated as 7,178,000t with functioning flood-preventing facilities and 11,956,000t without functioning flood prevention facilities...
June 17, 2017: Waste Management
https://www.readbyqxmd.com/read/28630697/the-effect-of-position-on-the-precision-of-dual-energy-x-ray-absorptiometry-and-correlation-with-body-condition-score-in-dogs-and-cats
#8
Charlotte R Bjørnvad, Mie E Nielsen, Susanna E M Hansen, Dorte H Nielsen
Dual-energy X-ray absorptiometry (DEXA) has been used to assess body composition in dogs and cats in several studies, but studies are difficult to compare for several reasons. The aim of the present study was to evaluate whether positioning of dogs or cats in either dorsal or ventral recumbency during DEXA scanning influences results. Dogs and cats that were brought to the University Hospital for Companion Animals for euthanasia during the period 15 September-6 November 2015 were consecutively recruited if owners signed a written consent...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28626101/-comparison-of-short-term-outcomes-between-minimally-invasive-mckeown-esophagectomy-and-ivor-lewis-esophagectomy-for-esophageal-cancer
#9
Xiong Peng, Yun Chen, Abdillah Nassor Juma, Yanqing Wang, Yuan Zhou, Yang Jiao, Weixing Zhang, Wei Zhuang
To summarize the outcomes of 74 patients with minimally invasive McKeown esophagectomy (MIE-McKeown), and to discuss the short-term outcomes by comparing with Ivor-Lewis esophagectomy (ILE) procedure.
 Methods: A total of 74 patients with esophageal carcinoma underwent MIE-McKeown in Xiangya Hospital from November 2014 to July 2016 were retrospectively reviewed, and 85 patients underwent ILE procedure were selected as a control group. Perioperative and short-term outcomes were analyzed.
 Results: Compared with the ILE group, patients underwent MIE-McKeown had less blood loss, less pulmonary infection, longer resection length and more harvested lymph nodes (P<0...
May 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28624989/ponderal-index-at-birth-associates-with-later-risk-of-gestational-diabetes-mellitus
#10
Mie Crusell, Peter Damm, Torben Hansen, Oluf Pedersen, Charlotte Glümer, Allan Vaag, Jeannet Lauenborg
PURPOSE: Low birth weight (BW) and low ponderal index (PI) are associated with increased risk of type 2 diabetes mellitus. This study has two purposes: first to investigate the influence of PI on the risk of gestational diabetes mellitus (GDM); second, to study the association between glucose metabolism and BW in women with previous GDM. METHODS: GDM cohort: 185 women with GDM in 1978-1996, attending a follow-up study in 2000-2002. Control cohort: 1137 women from a population-based diabetes screening study (Inter99) in a neighbouring county in 1999-2001...
June 17, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28612179/efficacy-safety-and-pharmacokinetics-of-up-to-two-courses-of-the-rituximab-biosimilar-ct-p10-versus-innovator-rituximab-in-patients-with-rheumatoid-arthritis-results-up-to-week-72-of-a-phase-i-randomized-controlled-trial
#11
Dae Hyun Yoo, Chang-Hee Suh, Seung Cheol Shim, Slawomir Jeka, Francisco Fidencio Cons Molina, Pawel Hrycaj, Piotr Wiland, Eun Young Lee, Francisco G Medina-Rodriguez, Pavel Shesternya, Sebastiao Radominski, Marina Stanislav, Volodymyr Kovalenko, Dong Hyuk Sheen, Leysan Myasoutova, Mie Jin Lim, Jung-Yoon Choe, Sang Joon Lee, Sung Young Lee, Sung Hwan Kim, Won Park
BACKGROUND: CT-P10 is a biosimilar of innovator rituximab (RTX), a biological therapy used to treat patients with rheumatoid arthritis (RA) who have responded inadequately to anti-tumor necrosis factor agents. OBJECTIVE: Our objective was to compare the clinical profile of CT-P10 versus RTX in patients with RA who received up to two courses of treatment and were followed for up to 72 weeks. METHODS: In this multicenter double-blind phase I study, patients were randomized 2:1 to receive CT-P10 1000 mg or RTX 1000 mg at weeks 0 and 2...
June 13, 2017: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/28608891/salt-induced-cluster-formation-of-gold-nanoparticles-followed-by-stopped-flow-saxs-dls-and-extinction-spectroscopy
#12
Nico Carl, Sylvain Prévost, Joseph P S Fitzgerald, Matthias Karg
In this work we investigate the salt-induced cluster formation of monodisperse, spherical gold nanoparticles possessing negative surface charge. Time dependent dynamic light scattering was used to determine the critical coagulation concentration and to study the kinetics of cluster growth. Cryo-TEM as well as small angle X-ray scattering allowed to obtain insights into the cluster morphology at various salt concentrations. The time dependent cluster growth was monitored by stopped-flow small angle X-ray scattering experiments and UV-Visible extinction measurements simultaneously...
June 13, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28607286/morbidity-analysis-in-minimally-invasive-esophagectomy-for-oesophageal-cancer-versus-conventional-over-the-last-10-years-a-single-institution-experience
#13
Misbah Khan, Muhammad Ijaz Ashraf, Aamir Ali Syed, Shahid Khattak, Namra Urooj, Anam Muzaffar
BACKGROUND: There has been an increasing inclination towards minimally invasive esophagectomies (MIEs) at our institute recently for resectable oesophageal cancer. OBJECTIVES: The purpose of the present study is to report peri-operative and long-term procedure specific outcomes of the two groups and analyse their changing pattern at our institute. METHODS: All adult patients with a diagnosis of oesophageal cancer managed at our institute from 2005 to 2015 were included in this retrospective study...
July 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28606211/specialized-palliative-care-in-advanced-cancer-what-is-the-efficacy-a-systematic-review
#14
Kristina Holmenlund, Per Sjøgren, Mie Nordly
OBJECTIVE: Due to the multiple physical, psychological, existential, and social symptoms involved, patients with advanced cancer often have a reduced quality of life (QoL), which requires specialized palliative care (SPC) interventions. The primary objective of the present systematic review was to review the existing literature about SPC and its effect on QoL, on physical and psychological symptoms, and on survival in adult patients with advanced cancer. METHOD: We utilized a search strategy based on the PICO (problem/population, intervention, comparison, and outcome) framework and employed terminology related to cancer, QoL, symptoms, mood, and palliative care...
June 13, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28603159/safety-profile-of-telaprevir-based-triple-therapy-in-elderly-patients-a-real-world-retrospective-cohort-study
#15
Maiko Akutagawa, Kazuki Ide, Yohei Kawasaki, Mie Yamanaka, Ryo Iketani, Hiroshi Yamada, Naohiko Masaki
To compare the rate of treatment discontinuation due to adverse events for telaprevir-based triple (T/PR) and pegylated interferon-alfa-2b and ribavirin (PR) therapy for the treatment of hepatitis C virus (HCV) infection in patients over the age of 65 years, in Japan.Retrospective analysis of the health data of patients over the age of 65 years treated for a HCV infection genotype 1 using T/PR or PR therapy, from 38 prefectures in Japan. The primary outcome was the rate of treatment discontinuation due to adverse events for T/PR and PR...
June 9, 2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28602088/extension-of-the-saft-vr-mie-eos-to-model-homonuclear-rings-and-its-parameterization-based-on-the-principle-of-corresponding-states
#16
Erich A Muller, Andrés Mejía
The statistical associating fluid theory of variable range employing a Mie potential (SAFT-VR-Mie) proposed by Lafitte et al. [J. Chem Phys. 2013, 139, 154504] is one of the latest versions of the SAFT family. This particular version has been shown to have a remarkable capability to connect experimental determinations, theoretical calculations and molecular simulations results. However, the theoretical development restricts the model to chains of beads connected in a linear fashion. In this work, the capabilities of the SAFT-VR Mie equation of state for modeling phase equilibria are extended for the case of planar ring compounds...
June 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28600696/efficacy-and-safety-of-switching-from-innovator-rituximab-to-biosimilar-ct-p10-compared-with-continued-treatment-with-ct-p10-results-of-a-56-week-open-label-study-in-patients-with-rheumatoid-arthritis
#17
Won Park, Chang-Hee Suh, Seung Cheol Shim, Francisco Fidencio Cons Molina, Slawomir Jeka, Francisco G Medina-Rodriguez, Pawel Hrycaj, Piotr Wiland, Eun Young Lee, Pavel Shesternya, Volodymyr Kovalenko, Leysan Myasoutova, Marina Stanislav, Sebastiao Radominski, Mie Jin Lim, Jung-Yoon Choe, Sang Joon Lee, Sung Young Lee, Sung Hwan Kim, Dae Hyun Yoo
BACKGROUND: CT-P10 is a biosimilar candidate of innovator rituximab (RTX) that demonstrated a comparable clinical profile to RTX in a phase I randomized controlled trial (RCT) in rheumatoid arthritis (RA) (ClinicalTrials.gov identifier: NCT01534884). OBJECTIVE: This open-label extension (OLE) study (NCT01873443) compared the efficacy and safety of CT-P10 in patients with RA who received CT-P10 from the outset (i.e., from the start of the RCT and also in the OLE; 'maintenance group') with those who received RTX during the RCT and switched to CT-P10 during the OLE ('switch group')...
June 9, 2017: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/28596244/weight-cycling-and-the-subsequent-onset-of-type-2-diabetes-mellitus-10-year-cohort-studies-in-urban-and-rural-japan
#18
Hiroshi Yokomichi, Sachiko Ohde, Osamu Takahashi, Mie Mochizuki, Atsunori Takahashi, Yoshioki Yoda, Masahiro Tsuji, Yuka Akiyama, Zentaro Yamagata
OBJECTIVE: To investigate how weight cycling (gaining and losing weight) affects the risk of diabetes. DESIGN: Cohort studies. SETTING: Primary healthcare in urban and rural Japan. PARTICIPANTS: 20 708 urban and 9670 rural residents. PRIMARY OUTCOME MEASURES: ORs for diabetes in those with weight loss, weight loss-gain, stable weight, weight gain-loss and weight gain over 10 years. Weight gain and loss were defined as a change of more than ±4% from baseline weight...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28593716/does-an-epidemiological-comparison-support-a-common-cellular-lineage-for-similar-subtypes-of-postmenopausal-uterine-and-ovarian-carcinoma-the-norwegian-women-and-cancer-study
#19
Mie Jareid, Idlir Licaj, Karina Standahl Olsen, Eiliv Lund, Hege M Bøvelstad
Uterine and ovarian carcinomas have the same major histological subtypes, but whether they originate from the same cell types is a matter of ongoing debate. Uterine and ovarian endometrioid and clear cell carcinoma (ECC) and uterine and ovarian serous carcinoma (SC) may originate in the same location, or share a common lineage of differentiation. Epidemiologically, a common cellular lineage should be reflected in similar risk associations, and we explored the similarity of uterine and ovarian ECC and uterine and ovarian SC...
June 8, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28593693/double-gold-activation-of-1-ethynyl-2-phenylethynyl-benzene-toward-5-exo-dig-and-6-endo-dig-cyclization-reactions
#20
Nery Villegas-Escobara, Mie Hojer Vilhelmsen, Soledad Gutierrez-Oliva, A Stephen K Hashmi, Alejandro Toro-Labbé
In this work, a detailed characterization of the ring closure mechanism of EPB (1-ethynyl-2-(phenylethynyl)benzene) toward the 5-exo-dig and 6-endo-dig cyclization reactions catalyzed by two Au-NHC moieties was carried out. It was found that the 5-exo-dig cyclization takes place with a slightly lower activation barrier and larger exothermicity compared to that of the 6-endo-dig cyclization, in Agreement with the available experimental data. A phenomenological partition (structural and electronic) for rate constants computed using transition state theory and the reaction force analysis was used to shed light into the nature of the activation rate constant...
June 7, 2017: Chemistry: a European Journal
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