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Panretinal laser photocoagulation

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https://www.readbyqxmd.com/read/28427069/practical-lessons-from-protocol-i-for-the-management-of-diabetic-macular-edema
#1
Lekha Mukkamala, Neelakshi Bhagat, Marco A Zarbin
Protocol I, a multicenter randomized clinical trial, compared the visual outcomes of patients treated with 0.5 mg intravitreal ranibizumab with either prompt or deferred (by 24 weeks laser), 4 mg intravitreal triamcinolone with prompt laser, or sham injection with prompt laser for the treatment of center-involving diabetic macular edema (DME). A total of 854 adult patients with type I or II diabetes and any level of non-proliferative diabetic retinopathy or proliferative retinopathy with adequate panretinal photocoagulation, with best-corrected visual acuity (BCVA) of 78 to 24 ETDRS letters (Snellen equivalent of 20/32 to 20/320) and visual loss attributed to macular edema, or retinal thickening with central subfield thickness of at least 250 µm by OCT were enrolled...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28367188/efficacy-of-intravitreal-bevacizumab-combined-with-pan-retinal-photocoagulation-versus-panretinal-photocoagulation-alone-in-treatment-of-proliferative-diabetic-retinopathy
#2
Murtaza Sameen, Muhammad Saim Khan, Ahsan Mukhtar, Muhammad Amer Yaqub, Mazhar Ishaq
OBJECTIVE: To compare effectiveness of pan-retinal photocoagulation alone versus panretinal photocoagulation combined with intravitreal bevacizumab on visual acuity and central macular thickness in patients presenting with proliferative diabetic retinopathy. METHODS: This Randomized controlled trial was carried out at Armed Forces Institute of ophthalmology, Pakistan from Jan 2016 to Aug 2016. Seventy six eyes of 50 patients having proliferative diabetic retinopathy and diabetic macular edema were included in the study...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28355247/effects-of-photocoagulation-on-ocular-blood-flow-in-patients-with-severe-non-proliferative-diabetic-retinopathy
#3
Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Eimei Ra, Hiroko Terasaki
PURPOSE: To investigate ocular blood flow and correlations between ocular blood flow and variables in patients with severe non-proliferative diabetic retinopathy (S-NPDR) following panretinal photocoagulation (PRP). METHODS: In this retrospective, cross-sectional study, the blood flow on the optic nerve head (ONH) and choroid was assessed with laser speckle flowgraphy (LSFG) using the mean blur rate (MBR) in 76 eyes of 76 patients with S-NPDR who underwent PRP, 39 eyes of 39 patients with S-NPDR who did not undergo PRP, and 71 eyes of 71 normal subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28339297/long-term-effect-of-panretinal-photocoagulation-on-spectral-domain-optical-coherence-tomography-measurements-in-diabetic-retinopathy
#4
Haeng-Jin Lee, Tae-Seen Kang, Baek-Soo Kwak, Young-Joon Jo, Jung-Yeul Kim
PURPOSE: To evaluate the effects of panretinal photocoagulation on spectral domain optical coherence tomography measurements in diabetic retinopathy by comparing the thicknesses of the central macula, retinal nerve fiber layer, and ganglion cell layer, we used a Cirrus HD OCT® (Carl Zeiss Meditec, Dublin, CA, USA) in normal and diabetic retinopathy cohorts. METHODS: We analyzed patients who visited our retinal clinic between May 2013 and July 2014. The patients were classified into four groups: normal (Group A), diabetes without diabetic retinopathy (Group B), severe nonproliferative or proliferative diabetic retinopathy (Group C), and at least 3 years after panretinal photocoagulation treatment (Group D)...
March 24, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28283281/trends-in-vitreoretinal-procedures-for-medicare-beneficiaries-2000-to-2014
#5
Michael D McLaughlin, John C Hwang
TOPIC: The purpose of this study was to identify changes in use for vitreoretinal procedures by measuring the number of allowed services using data from the US Medicare Part B Fee-for-Service (FFS) beneficiaries and their providers. CLINICAL RELEVANCE: To analyze vitreoretinal procedural trends, which may indicate standard of care and importance of developing methods of treatments. METHODS: Medicare Part B National Summary Data Files for calendar years 2000 to 2014 were used to identify the number of allowed services for vitreoretinal procedures and commonly used pharmacologic agents...
March 7, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28182169/comparison-of-efficacy-and-side-effects-of-multispot-lasers-and-conventional-lasers-for-diabetic-retinopathy-treatment
#6
REVIEW
Hande Çeliker, Azer Erdağı Bulut, Özlem Şahin
Panretinal photocoagulation (PRP) is a standard treatment for proliferative diabetic retinopathy. Conventional laser (CL) therapy is performed in one or more sessions in single spot mode. Visual disabilities have been reported after treatment with CL, including central vision loss due to macular edema and peripheral visual field loss resulting from extensive inner retinal scarring. Multispot laser (MSL) photocoagulation has recently been introduced to clinical practice. Studies comparing PRP conducted with MSL and CL have reported that MSLs resulted in less retinal tissue damage and pain, and greater patient comfort compared to CL...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28168567/extended-targeted-retinal-photocoagulation-versus-conventional-pan-retinal-photocoagulation-for-proliferative-diabetic-retinopathy-in-a-randomized-clinical-trial
#7
Homayoun Nikkhah, Hossein Ghazi, Mohammad Reza Razzaghi, Saeed Karimi, Alireza Ramezani, Masoud Soheilian
PURPOSE: To determine the clinical efficacy of extended targeted retinal photocoagulation (ETRP) compared to conventional panretinal photocoagulation (CPRP) in proliferative diabetic retinopathy (PDR). METHODS: In a single-masked randomized clinical trial, 270 eyes of 234 patients with naïve early or high-risk PDR were randomly assigned to receive either CPRP or ETRP (135 eyes, each treatment arm). Best-corrected visual acuity (BCVA) measurement, fundus examination, wide-field fluorescein angiography (WFFA) and optical coherence tomography were carried out before and 3 months after retinal photocoagulation...
February 6, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28127735/effects-of-panretinal-laser-photocoagulation-on-the-corneal-nerve-plexus-and-retinal-nerve-fiber-layer-in-retinal-vein-occlusion
#8
Gulfidan Bitirgen, Selman Belviranli, Rayaz A Malik, Hurkan Kerimoglu, Ahmet Ozkagnici
PURPOSE: To determine the effects of panretinal photocoagulation (PRP) on corneal sub-basal nerve plexus (SBNP) and peripapillary retinal nerve fiber layer (RNFL) thickness in patients with unilateral central retinal vein occlusion (CRVO) who had previously undergone PRP treatment. METHODS: Sixty-four eyes of 32 patients (19 male, 13 female) with unilateral ischemic type CRVO who had undergone PRP treatment at least 6 months previously were included in this cross-sectional study...
January 23, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28009403/ocular-pulse-amplitude-after-panretinal-photocoagulation-in-normotensive-eyes-with-proliferative-diabetic-retinopathy
#9
Marija M Bozic, Jelena B Karadzic, Igor M Kovacevic, Ivan S Marjanovic
PURPOSE: To assess the effect of panretinal laser photocoagulation on ocular pulse amplitude (OPA) in normotensive eyes with proliferative diabetic retinopathy. METHODS: Prospectively, we performed unilateral argon laser panretinal photocoagulation (PRP) in 30 patients with diabetes mellitus type II and previously untreated bilateral proliferative diabetic retinopathy. Before and 7 and 30 days after the treatment, OPA was measured using dynamic contour tonometer...
November 28, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27895936/neovascular-glaucoma-a-review
#10
REVIEW
Gustavo B Rodrigues, Ricardo Y Abe, Camila Zangalli, Savio L Sodre, Flavia A Donini, Danilo C Costa, Andre Leite, Joao P Felix, Marcelo Torigoe, Alberto Diniz-Filho, Homero Gusmão de Almeida
Neovascular glaucoma (NVG) is a secondary glaucoma generally associated with poor visual prognosis. The development of new vessels over the iris and the iridocorneal angle can obstruct aqueous humor outflow and lead to increased intraocular pressure. The underlying pathogenesis in most cases is posterior segment ischemia, which is most commonly secondary to proliferative diabetic retinopathy or central vein retinal occlusion. The neovascularization process in the eye is driven by the events that alter the homeostatic balance between pro-angiogenic factors, such as the vascular endothelial growth factor and anti-angiogenic factors, such as the pigment-epithelium-derived factor...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27766582/vascular-endothelial-growth-factor-inhibitors-for-diabetic-retinopathy
#11
Dilsher S Dhoot, Robert L Avery
The prevalence of diabetes is growing at epidemic rates in the USA. Diabetic retinopathy develops in a large proportion of patients and is a leading cause of blindness worldwide. Systemic management of diabetic retinopathy has included glycemic, hypertension, and lipid control. Local ophthalmic treatment in the form of focal/grid or panretinal laser photocoagulation has been shown to prevent vision loss in diabetic edema and proliferative diabetic retinopathy, respectively. The introduction of anti-vascular endothelial growth factor for diabetic macular edema and retinopathy has provided clinicians with improved clinical outcomes with potentially less damaging effects than laser...
December 2016: Current Diabetes Reports
https://www.readbyqxmd.com/read/27715375/changes-in-the-macular-ganglion-cell-complex-thickness-and-central-macular-thickness-after-argon-laser-panretinal-photocoagulation
#12
Gülizar Demirok, Mehmet Fatih Kocamaz, Yasemin Topalak, Yeşim Altay, Burcu Tabakci, Ahmet Şengün
PURPOSE: To evaluate the changes in the macular ganglion cell complex (GCC) thickness and central macular thickness (CMT) as measured by spectral domain optical coherence tomography (OCT) post-argon laser panretinal photocoagulation (PRP). METHODS: The medical records of 25 patients with proliferative diabetic retinopathy (PDR) who underwent PRP, 29 patients with non-proliferative diabetic retinopathy (NPDR), and 29 patients with diabetes but without diabetic retinopathy (DR) were analyzed...
August 10, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27664228/management-of-postvitrectomy-retinal-detachment-due-to-multiple-laser-induced-retinal-holes
#13
Vinod Kumar, Shreyans Jain, Parijat Chandra, Atul Kumar
A 25-year-old man presented with retinal detachment in his right eye 20 days after pars plana vitrectomy, epiretinal membrane peeling and endolaser assisted panretinal photocoagulation performed for non-resolving vitreous haemorrhage secondary to Eales disease. Inferior retina of the right eye showed multiple (around 120) retinal holes in relation to the previous photocoagulation marks. The patient was managed with repeat vitrectomy, endolaser and silicone oil infusion. The aetiology of multiple holes, precautions to prevent them and their management are described...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27646339/simulation-of-panretinal-laser-photocoagulation-using-geometric-methods-for-calculating-the-photocoagulation-index
#14
Kentaro Nishida, Hirokazu Sakaguchi, Motohiro Kamei, Nobuhiko Shiraki, Yoshihito Oura, Taku Wakabayashi, Chikako Hara, Yoko Fukushima, Tatsuhiko Sato, Kaori Sayanagi, Shigeru Sato, Masakatsu Fukuda, Kohji Nishida
PURPOSE: To establish geometrically based methods for simulating panretinal laser photocoagulation (PRP) for the photocoagulation index. METHODS: A formula for calculating the curved surface area of a spherical dome was used for the simulation. If the radius of the dome is c and the height of the dome is h, then the curved surface area (S) of the dome is S = π (c2 + h2). We calculated the area of the whole retina using this formula and the anatomical dimensions of the standard eyeball...
March 10, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27625747/treatment-of-diabetic-retinopathy-recent-advances-and-unresolved-challenges
#15
REVIEW
Michael W Stewart
Diabetic retinopathy (DR) is the leading cause of blindness in industrialized countries. Remarkable advances in the diagnosis and treatment of DR have been made during the past 30 years, but several important management questions and treatment deficiencies remain unanswered. The global diabetes epidemic threatens to overwhelm resources and increase the incidence of blindness, necessitating the development of innovative programs to diagnose and treat patients. The introduction and rapid adoption of intravitreal pharmacologic agents, particularly drugs that block the actions of vascular endothelial growth factor (VEGF) and corticosteroids, have changed the goal of DR treatment from stabilization of vision to improvement...
August 25, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27625164/morphological-and-functional-changes-in-recalcitrant-diabetic-macular-oedema-after-intravitreal-dexamethasone-implant
#16
Pierluigi Iacono, Maurizio Battaglia Parodi, Matteo Scaramuzzi, Francesco Bandello
BACKGROUND: To evaluate the effects of dexamethasone implant in eyes affected by recalcitrant diabetic macular oedema (DME) associated with proliferative diabetic retinopathy (PDR). METHODS: Thirteen consecutive patients with centre-involving DME associated with PDR, central macular thickness (CMT) ≥300 µm, previous therapy with panretinal photocoagulation, focal/grid laser treatment and anti-vascular endothelial growth factor injection were prospectively enrolled...
September 13, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27595017/subfoveal-choroidal-thickness-after-panretinal-photocoagulation-with-red-and-green-laser-in-bilateral-proliferative-diabetic-retinopathy-patients-short-term-results
#17
Ramak Roohipoor, Sina Dantism, Aliasghar Ahmadraji, Reza Karkhaneh, Mohammad Zarei, Fariba Ghasemi
Purpose. To compare subfoveal choroidal, central retinal, and peripapillary nerve fiber layer (RNFL) thickness after panretinal photocoagulation (PRP) with red and green laser in diabetic patients. Study Design. Randomized clinical trial. Methods. A total of 50 patients with bilateral proliferative diabetic retinopathy and no diabetic macular edema underwent PRP. One eye was randomly assigned to red or green laser. Subfoveal choroidal, central retinal, and RNFL thicknesses were evaluated at baseline and 6 weeks after treatment...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27479624/vision-loss-in-older-adults
#18
REVIEW
Allen L Pelletier, Ledy Rojas-Roldan, Janis Coffin
Vision loss affects 37 million Americans older than 50 years and one in four who are older than 80 years. The U.S. Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for impaired visual acuity in adults older than 65 years. However, family physicians play a critical role in identifying persons who are at risk of vision loss, counseling patients, and referring patients for disease-specific treatment. The conditions that cause most cases of vision loss in older patients are age-related macular degeneration, glaucoma, ocular complications of diabetes mellitus, and age-related cataracts...
August 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27472514/successful-treatment-of-refractory-proliferative-retinopathy-of-incontinentia-pigmenti-by-intravitreal-ranibizumab-as-adjunct-therapy-in-a-4-year-old-child
#19
Mary Ho, Wilson W K Yip, Vesta C K Chan, Alvin L Young
PURPOSE: To describe a case of incontinentia pigmenti with proliferative retinopathy successfully treated by combination of repeated retinal laser photocoagulation and intravitreal ranibizumab injection. METHODS: Single interventional case report of a 4-year-old girl, known case of incontientia pigmenti, first screened at the age of two, presented with proliferative retinopathy. Sole treatment by panretinal laser photocoagulation failed to control the progression of retinal neovascularization...
July 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27429384/intravitreal-bevacizumab-for-proliferative-diabetic-retinopathy-results-from-the-pan-american-collaborative-retina-study-group-pacores-at-24-months-of-follow-up
#20
J Fernando Arevalo, Andres F Lasave, Lihteh Wu, Mauricio Maia, Manuel Diaz-Llopis, Arturo A Alezzandrini, Miguel Brito
PURPOSE: To evaluate the effects of intravitreal bevacizumab (IVB) on retinal neovascularization in patients with proliferative diabetic retinopathy (PDR). METHODS: Retrospective multicenter interventional case series. A chart review was performed of 81 consecutive patients (97 eyes) with retinal neovascularization due to PDR, who received at least 1 IVB injection. RESULTS: The mean age of the patients was 55.6 ± 11.6 years. The mean number of IVB injections was 4 ± 2...
February 2017: Retina
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