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Panretinal laser photocoagulation

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https://www.readbyqxmd.com/read/29121367/idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-syndrome-presenting-with-branch-retinal-artery-occlusion
#1
Jennifer A Zacharia, Adam T Chin, Carl B Rebhun, Ricardo N Louzada, Mehreen Adhi, Emily D Cole, Carlos Moreira-Neto, Nadia K Waheed, Jay S Duker
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) is a rare syndrome affecting the retinal and optic disc vasculature. Diffuse retinal ischemia, macular edema, and neovascularization may lead to bilateral vision loss. The authors report a case of a 36-year-old woman presenting with branch retinal artery occlusion (BRAO) in her right eye who was subsequently diagnosed with IRVAN syndrome. She was treated with panretinal photocoagulation for peripheral retinal ischemia and pars plana vitrectomy for vitreous hemorrhage...
November 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29121359/single-spot-yellow-laser-versus-conventional-green-laser-on-panretinal-photocoagulation-patient-pain-scores-and-preferences
#2
Gerardo González-Saldivar, Sergio Rojas-Juárez, Itzel Espinosa-Soto, Jorge Sánchez-Ramos, Noel Jaurieta-Hinojosa, Abel Ramírez-Estudillo
BACKGROUND AND OBJECTIVE: Panretinal photocoagulation (PRP) is the mainstay therapy for proliferative diabetic retinopathy. Pain during and after its application is a complication that affects patients' therapeutic adherence. This study aimed to compare pain perception and patient preference for the 577-nm yellow laser (YL-577) (LIGHTL as 577; LIGHTMED, San Clemente, CA) and the conventional 532-nm green laser (GL-532) (Purepoint Laser; Alcon, Fort Worth, TX) with PRP. PATIENTS AND METHODS: A total of 92 patient eyes with proliferative diabetic retinopathy treated with PRP were randomly assigned to receive both GL-532 and YL-577 (184 eyes) - one on each eye, with the order of application randomized, as well...
November 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29098298/photocoagulation-of-the-retinal-nonperfusion-area-prevents-the-expression-of-the-vascular-endothelial-growth-factor-in-an-animal-model
#3
Makoto Gozawa, Yoshihiro Takamura, Seiji Miyake, Takehiro Matsumura, Masakazu Morioka, Yutaka Yamada, Masaru Inatani
Purpose: The purpose of this study was to evaluate whether photocoagulation of the retinal nonperfusion area suppresses ocular vascular endothelial growth factor (VEGF) expression in a rabbit retinal vein occlusion (RVO) model. Methods: The retinas of pigmented rabbits were made ischemic by a laser on the main branch of retinal veins following intravenous injection of Rose Bengal. The eyes were enucleated before treatment and at 1, 7, and 14 days after laser occlusion...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29074011/analysis-of-reasons-for-noncompliance-with-laser-treatment-in-patients-of-diabetic-retinopathy
#4
Wen Hua, Sijia Cao, Jing Cui, David Maberley, Joanne Matsubara
OBJECTIVE: To identify the underlying reasons for noncompliance among Chinese patients undergoing laser photocoagulation treatment for diabetic retinopathy (DR). DESIGN: Prospective cohort study. PARTICIPANTS: A total of 262 patients with DR with indications for panretinal photocoagulation and focal laser treatment were recruited. METHODS: Those who did not complete the prescribed laser treatment were categorized into 2 types of defaulters: Type 1 defaulters were those who did not initiate laser treatment as scheduled; type 2 defaulters were those who did not complete the entire laser sessions, including terminating midterm or defaulting prompt supplement of laser treatment...
November 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29020428/improvement-of-recalcitrant-diabetic-macular-edema-after-peritoneal-dialysis
#5
Sally S Ong, Akshay S Thomas, Sharon Fekrat
Nephropathy may be an independent and contributory risk factor for diabetic macular edema (DME). A 69-year-old man who had previously been treated with panretinal laser photocoagulation for proliferative diabetic retinopathy as well as with steroid and anti-vascular endothelial growth factor injections for DME declined additional treatment for the DME, which was worse in the right eye. The DME was observed without further treatment for the next 36 months. Despite well-controlled blood sugar, blood pressure, and lipid levels, the DME remained unchanged...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28937857/evaluation-of-retinal-blood-flow-before-and-after-panretinal-photocoagulation-using-pattern-scan-laser-for-diabetic-retinopathy
#6
Yoshihisa Yamada, Kiyoshi Suzuma, Naoko Onizuka, Masafumi Uematsu, Yasser Helmy Mohamed, Takashi Kitaoka
PURPOSE: Laser speckle flowgraphy (LSFG) can measure blood flow in the ocular fundus. We analyzed the relationship between retinal blood flow and panretinal photocoagulation (PRP) in diabetic retinopathy. METHODS: This retrospective observational study examined the eyes of 35 patients with proliferative diabetic retinopathy (PDR) or non-PDR (NPDR). PRP was performed using a pattern scan laser. Using LSFG, blood flow was evaluated as the mean blur rate (MBR) or the relative flow volume (RFV)...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28790803/the-outcome-of-low-frequency-intravitreal-bevacizumab-therapy-for-macular-edema-in-retinal-vein-occlusions
#7
Biljana Ivanovska Adjievska, Salih Boskurt, Nikola Orovcanec, Vesna Dimovska-Jordanova
AIM: We aimed to evaluate the 1-year efficacy and safety of low-frequency intravitreal bevacizumab in the treatment of macular edema due to retinal vein occlusions (RVOs). METHODS: The study comprised an interventional prospective study of patients with macular edema due to central retinal vein occlusion (CRVO) or branch retinal vein occlusion, followed for 12 months. Treatment-naïve patients with reduced best-corrected visual acuity (BCVA) and central macular thickness (CMT) of at least 250 μm received intravitreal injection of bevacizumab...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28765148/changes-in-retinal-venular-oxygen-saturation-predict-activity-of-proliferative-diabetic-retinopathy-3-months-after-panretinal-photocoagulation
#8
Thomas Lee Torp, Ryo Kawasaki, Tien Yin Wong, Tunde Peto, Jakob Grauslund
BACKGROUND/AIMS: Proliferative diabetic retinopathy (PDR) is a severe blinding condition. We investigated whether retinal metabolism, measured by retinal oximetry, may predict PDR activity after panretinal laser photocoagulation (PRP). METHODS: We performed a prospective, interventional, clinical study of patients with treatment-naive PDR. Wide-field fluorescein angiography (OPTOS, Optomap) and global and focal retinal oximetry (Oxymap T1) were performed at baseline (BL), and 3 months (3M) after PRP...
August 1, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28761761/panretinal-photocoagulation-using-short-pulse-laser-induces-less-inflammation-and-macular-thickening-in-patients-with-diabetic-retinopathy
#9
Yoshihiro Takamura, Shogo Arimura, Seiji Miyake, Takehiro Matsumura, Makoto Gozawa, Kentaro Iwasaki, Masaru Inatani
We compared the effect of panretinal photocoagulation (PRP) using short-pulse laser (SPL) and conventional laser, regardless of the number of spots, in terms of their effect on the progression of diabetic macular edema (DME) and anterior flare intensity (AFI) in patients with high-risk nonproliferative diabetic retinopathy (non-PDR). Forty-two eyes of 42 patients were subjected to PRP using the conventional argon laser (Conv group) or SPL (SPL group). CRT and AFI levels in the SPL group were significantly lower than those in the Conv group (CRT at 4, 6, and 10 weeks; AFI at 6, 10, and 18 weeks)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28570735/accuracy-of-billing-codes-used-in-the-therapeutic-care-of-diabetic-retinopathy
#10
MULTICENTER STUDY
Marisa Lau, Jonathan L Prenner, Alexander J Brucker, Brian L VanderBeek
Importance: Insurance billing claim databases represent a growing field of scientific inquiry within ophthalmology. Validating the accuracy of billing claim codes used during the care of diabetic retinopathy is a necessary precursor to fully understanding the underlying data and subsequent results of these types of studies. Objective: To determine the accuracy of diagnostic, procedural, and therapeutic billing codes used in the treatment of diabetic retinopathy...
July 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28570733/results-of-a-randomized-clinical-trial-of-aflibercept-vs-panretinal-photocoagulation-for-proliferative-diabetic-retinopathy-is-it-time-to-retire-your-laser
#11
https://www.readbyqxmd.com/read/28494920/clinical-efficacy-of-intravitreal-aflibercept-versus-panretinal-photocoagulation-for-best-corrected-visual-acuity-in-patients-with-proliferative-diabetic-retinopathy-at-52-weeks-clarity-a-multicentre-single-blinded-randomised-controlled-phase-2b-non-inferiority
#12
Sobha Sivaprasad, A Toby Prevost, Joana C Vasconcelos, Amy Riddell, Caroline Murphy, Joanna Kelly, James Bainbridge, Rhiannon Tudor-Edwards, David Hopkins, Philip Hykin
BACKGROUND: Proliferative diabetic retinopathy is the most common cause of severe sight impairment in people with diabetes. Proliferative diabetic retinopathy has been managed by panretinal laser photocoagulation (PRP) for the past 40 years. We report the 1 year safety and efficacy of intravitreal aflibercept. METHODS: In this phase 2b, single-blind, non-inferiority trial (CLARITY), adults (aged ≥18 years) with type 1 or 2 diabetes and previously untreated or post-laser treated active proliferative diabetic retinopathy were recruited from 22 UK ophthalmic centres...
June 3, 2017: Lancet
https://www.readbyqxmd.com/read/28452993/structural-and-functional-changes-to-the-retina-and-optic-nerve-following-panretinal-photocoagulation-over-a-2-year-time-period
#13
R Filek, P Hooper, T Sheidow, J Gonder, D K Varma, L Heckler, W Hodge, S Chakrabarti, C M L Hutnik
PurposeTo evaluate long-term structural and functional changes to the retina and optic nerve following panretinal photocoagulation (PRP) in diabetic retinopathy (DR) patients.MethodsParticipants were patients with DR requiring PRP and control patients with DR not requiring PRP. The Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT) were performed to analyze the optic nerve and macula. Best-corrected visual acuity (BCVA) and visual field (VF) testing were done to measure central and peripheral vision...
August 2017: Eye
https://www.readbyqxmd.com/read/28427069/practical-lessons-from-protocol-i-for-the-management-of-diabetic-macular-edema
#14
REVIEW
Lekha Mukkamala, Neelakshi Bhagat, Marco A Zarbin
Protocol I, a multicenter randomized clinical trial, compared the visual outcomes of patients treated with 0.5 mg intravitreal ranibizumab with either prompt or deferred (by 24 weeks laser), 4 mg intravitreal triamcinolone with prompt laser, or sham injection with prompt laser for the treatment of center-involving diabetic macular edema (DME). A total of 854 adult patients with type I or II diabetes and any level of non-proliferative diabetic retinopathy or proliferative retinopathy with adequate panretinal photocoagulation, with best-corrected visual acuity (BCVA) of 78 to 24 ETDRS letters (Snellen equivalent of 20/32 to 20/320) and visual loss attributed to macular edema, or retinal thickening with central subfield thickness of at least 250 µm by OCT were enrolled...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28367188/efficacy-of-intravitreal-bevacizumab-combined-with-pan-retinal-photocoagulation-versus-panretinal-photocoagulation-alone-in-treatment-of-proliferative-diabetic-retinopathy
#15
Murtaza Sameen, Muhammad Saim Khan, Ahsan Mukhtar, Muhammad Amer Yaqub, Mazhar Ishaq
OBJECTIVE: To compare effectiveness of pan-retinal photocoagulation alone versus panretinal photocoagulation combined with intravitreal bevacizumab on visual acuity and central macular thickness in patients presenting with proliferative diabetic retinopathy. METHODS: This Randomized controlled trial was carried out at Armed Forces Institute of ophthalmology, Pakistan from Jan 2016 to Aug 2016. Seventy six eyes of 50 patients having proliferative diabetic retinopathy and diabetic macular edema were included in the study...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28355247/effects-of-photocoagulation-on-ocular-blood-flow-in-patients-with-severe-non-proliferative-diabetic-retinopathy
#16
Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Eimei Ra, Hiroko Terasaki
PURPOSE: To investigate ocular blood flow and correlations between ocular blood flow and variables in patients with severe non-proliferative diabetic retinopathy (S-NPDR) following panretinal photocoagulation (PRP). METHODS: In this retrospective, cross-sectional study, the blood flow on the optic nerve head (ONH) and choroid was assessed with laser speckle flowgraphy (LSFG) using the mean blur rate (MBR) in 76 eyes of 76 patients with S-NPDR who underwent PRP, 39 eyes of 39 patients with S-NPDR who did not undergo PRP, and 71 eyes of 71 normal subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28339297/long-term-effect-of-panretinal-photocoagulation-on-spectral-domain-optical-coherence-tomography-measurements-in-diabetic-retinopathy
#17
Haeng-Jin Lee, Tae-Seen Kang, Baek-Soo Kwak, Young-Joon Jo, Jung-Yeul Kim
PURPOSE: To evaluate the effects of panretinal photocoagulation on spectral domain optical coherence tomography measurements in diabetic retinopathy by comparing the thicknesses of the central macula, retinal nerve fiber layer, and ganglion cell layer, we used a Cirrus HD OCT® (Carl Zeiss Meditec, Dublin, CA, USA) in normal and diabetic retinopathy cohorts. METHODS: We analyzed patients who visited our retinal clinic between May 2013 and July 2014. The patients were classified into four groups: normal (Group A), diabetes without diabetic retinopathy (Group B), severe nonproliferative or proliferative diabetic retinopathy (Group C), and at least 3 years after panretinal photocoagulation treatment (Group D)...
August 2017: Current Eye Research
https://www.readbyqxmd.com/read/28283281/trends-in-vitreoretinal-procedures-for-medicare-beneficiaries-2000-to-2014
#18
MULTICENTER STUDY
Michael D McLaughlin, John C Hwang
TOPIC: The purpose of this study was to identify changes in use for vitreoretinal procedures by measuring the number of allowed services using data from the US Medicare Part B Fee-for-Service (FFS) beneficiaries and their providers. CLINICAL RELEVANCE: To analyze vitreoretinal procedural trends, which may indicate standard of care and importance of developing methods of treatments. METHODS: Medicare Part B National Summary Data Files for calendar years 2000 to 2014 were used to identify the number of allowed services for vitreoretinal procedures and commonly used pharmacologic agents...
May 2017: Ophthalmology
https://www.readbyqxmd.com/read/28182169/comparison-of-efficacy-and-side-effects-of-multispot-lasers-and-conventional-lasers-for-diabetic-retinopathy-treatment
#19
REVIEW
Hande Çeliker, Azer Erdağı Bulut, Özlem Şahin
Panretinal photocoagulation (PRP) is a standard treatment for proliferative diabetic retinopathy. Conventional laser (CL) therapy is performed in one or more sessions in single spot mode. Visual disabilities have been reported after treatment with CL, including central vision loss due to macular edema and peripheral visual field loss resulting from extensive inner retinal scarring. Multispot laser (MSL) photocoagulation has recently been introduced to clinical practice. Studies comparing PRP conducted with MSL and CL have reported that MSLs resulted in less retinal tissue damage and pain, and greater patient comfort compared to CL...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28168567/extended-targeted-retinal-photocoagulation-versus-conventional-pan-retinal-photocoagulation-for-proliferative-diabetic-retinopathy-in-a-randomized-clinical-trial
#20
Homayoun Nikkhah, Hossein Ghazi, Mohammad Reza Razzaghi, Saeed Karimi, Alireza Ramezani, Masoud Soheilian
PURPOSE: To determine the clinical efficacy of extended targeted retinal photocoagulation (ETRP) compared to conventional panretinal photocoagulation (CPRP) in proliferative diabetic retinopathy (PDR). METHODS: In a single-masked randomized clinical trial, 270 eyes of 234 patients with naïve early or high-risk PDR were randomly assigned to receive either CPRP or ETRP (135 eyes, each treatment arm). Best-corrected visual acuity (BCVA) measurement, fundus examination, wide-field fluorescein angiography (WFFA) and optical coherence tomography were carried out before and 3 months after retinal photocoagulation...
February 6, 2017: International Ophthalmology
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