keyword
MENU ▼
Read by QxMD icon Read
search

4D

keyword
https://www.readbyqxmd.com/read/28543598/assessment-of-fallopian-tube-fimbria-patency-with-4-dimensional-hysterosalpingo-contrast-sonography-in-infertile-women
#1
Weiqun Wang, Qiulan Zhou, Yafei Gong, Ying Li, Yinying Huang, Zhiyi Chen
OBJECTIVES: The purpose of this study was to evaluate the performance of 4-dimensional (4D) hysterosalpingo-contrast sonography (HyCoSy) for assessing fallopian tube fimbria patency in infertile women. METHODS: Seventy-seven infertile female patients with obstruction at the tubal fimbria or partial obstruction with pelvic adhesions were included. All of the patients underwent 4D HyCoSy enhanced by dynamic observation after a flush of normal saline and were followed with laparoscopic chromopertubation using methylene blue within 6 months...
May 24, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28542149/jak-stat-signaling-is-necessary-for-cell-monosis-prior-to-epithelial-cell-apoptotic-extrusion
#2
Alba Y Torres, Marianne Malartre, Anne-Marie Pret, François Agnès
Epithelial cell extrusion is crucial for proper development and tissue homeostasis. High-resolution 3D reconstruction and 4D imaging, combined with genetic analyis, have allowed us to reveal the highly-sterotyped morphogenetic events controlled by JAK/STAT signaling in a developmentally-programmed case of epithelial cell extrusion. Specialized somatic cells, Polar Cells (PCs), are produced in excess and then undergo apoptotic elimination from the follicular epithelium in the Drosophila ovary. We show that supernumerary PCs are first systematically enveloped by PC neighbors on all sides, first laterally, then apically in conjunction with highly-reinforced adherens junctions, and finally basally...
May 25, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28539219/discovery-of-pyrazolo-1-5-a-pyrimidine-3-carbonitrile-derivatives-as-a-new-class-of-histone-lysine-demethylase-4d-kdm4d-inhibitors
#3
Zhen Fang, Tian-Qi Wang, Hui Li, Guo Zhang, Xiao-Ai Wu, Li Yang, Yu-Lan Peng, Jun Zou, Lin-Li Li, Rong Xiang, Sheng-Yong Yang
Herein we report the discovery of a series of new small molecule inhibitors of histone lysine demethylase 4D (KDM4D). Molecular docking was first performed to screen for new KDM4D inhibitors from various chemical databases. Two hit compounds were retrieved. Further structural optimization and structure-activity relationship (SAR) analysis were carried out to the more selective one, compound 2, which led to the discovery of several new KDM4D inhibitors. Among them, compound 10r is the most potent one with an IC50 value of 0...
May 3, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28538602/pelvic-organ-prolapse-does-hormone-therapy-use-matter
#4
Erika J Wasenda, Ixora Kamisan Atan, Nishamini Subramaniam, Hans Peter Dietz
OBJECTIVE: To determine the effect of hormone therapy (HT) use on pelvic organ support. METHODS: A retrospective observational study involving postmenopausal women with pelvic floor dysfunction attending a tertiary urogynecology center between January 2012 and March 2015. All underwent a clinical examination including International Continence Society Pelvic Organ Prolapse Quantification and 4D translabial ultrasound imaging. Information on current or former use of systemic HT and current local estrogen use was collected...
May 22, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28537761/correlation-analysis-of-18-f-fluorodeoxyglucose-and-18-f-fluoroazomycin-arabinoside-uptake-distributions-in-lung-tumours-during-radiation-therapy
#5
Dario Di Perri, John A Lee, Anne Bol, François-Xavier Hanin, Guillaume Janssens, Daniel Labar, Annie Robert, Edmond Sterpin, Xavier Geets
BACKGROUND: PET-guided dose painting (DP) aims to target radioresistant tumour regions in order to improve radiotherapy (RT) outcome. Besides the well-known [(18)F]fluorodeoxyglucose (FDG), the hypoxia positron emission tomography (PET) tracer [(18)F]fluoroazomycin arabinoside (FAZA) could provide further useful information to guide the radiation dose prescription. In this study, we compare the spatial distributions of FDG and FAZA PET uptakes in lung tumours. MATERIAL AND METHODS: Fourteen patients with unresectable lung cancer underwent FDG and FAZA 4D-PET/CT on consecutive days at three time-points: prior to RT (pre), and during the second (w2), and the third (w3) weeks of RT...
May 24, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28537554/pioneer-neurog1-expressing-cells-ingress-into-the-otic-epithelium-and-instruct-neuronal-specification
#6
Esteban Hoijman, Laura Fargas, Patrick Blader, Berta Alsina
Neural patterning involves regionalised cell specification. Recent studies indicate that cell dynamics play instrumental roles in neural pattern refinement and progression, but the impact of cell behaviour and morphogenesis on neural specification is not understood. Here we combine 4D analysis of cell behaviours with dynamic quantification of proneural expression to uncover the construction of the zebrafish otic neurogenic domain. We identify pioneer cells expressing neurog1 outside the otic primordium that migrate and ingress into the epithelialising placode to become the first otic neuronal progenitors...
May 24, 2017: ELife
https://www.readbyqxmd.com/read/28537047/comparison-of-the-ratio-of-the-lenght-of-the-second-and-fourth-digits-in-subgroups-of-fertile-and-infertile-cases
#7
Emre Can Akinsal, Abdullah Demirtas, Oguz Ekmekcioglu
PURPOSE: To identify any relationship between known reasons of male infertility and 2D:4D ratio. MATERIALS AND METHODS: A total of 371 males were included in the study. The cases were grouped into 6 groups including sperm count < 5 million/mL, sperm count ≥ 5 million/mL, Klinefelter Syndrome, hypogonadotropic hypogonadism, vasal agenesis and control. Groups were compared with each other in terms of 2D:4D ratios and groups with a 2D:4D ratios below 1 and equal/above 1 were compared...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28535915/virtual-patient-3d-dose-reconstruction-using-in-air-epid-measurements-and-a-back-projection-algorithm-for-imrt-and-vmat-treatments
#8
Igor Olaciregui-Ruiz, Roel Rozendaal, René F M van Oers, Ben Mijnheer, Anton Mans
PURPOSE: At our institute, a transit back-projection algorithm is used clinically to reconstruct in vivo patient and in phantom 3D dose distributions using EPID measurements behind a patient or a polystyrene slab phantom, respectively. In this study, an extension to this algorithm is presented whereby in air EPID measurements are used in combination with CT data to reconstruct 'virtual' 3D dose distributions. By combining virtual and in vivo patient verification data for the same treatment, patient-related errors can be separated from machine, planning and model errors...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28533614/the-effect-of-bridge-exercise-method-on-the-strength-of-rectus-abdominis-muscle-and-the-muscle-activity-of-paraspinal-muscles-while-doing-treadmill-walking-with-high-heels
#9
Taewook Kang, Jaeseok Lee, Junghoon Seo, Dongwook Han
[Purpose] The purpose of this research is to investigate the effect of the method of bridge exercise on the change of rectus abdominis muscle and the muscle activity of paraspinal muscles while doing treadmill walking with high heels. [Subjects and Methods] The subjects of this research are healthy female students consisting of 10 persons performing bridge exercises in a supine group, 10 persons performing bridge exercises in a prone group, and 10 persons in a control group while in S university in Busan. Bridge exercise in supine position is performed in hook lying position...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28532524/is-maternal-periconceptional-smoking-associated-with-2d-4d-digit-ratio-in-their-children
#10
M P Velez, T E Arbuckle, P Monnier, W D Fraser
The 2nd--4th finger ratio (2D:4D) has been proposed as a potential indicator of greater androgen exposure during fetal development. Maternal periconceptional smoking may alter the homeostasis of fetal androgens, which could in turn result in differential development of 2D:4Ds in utero. The aim of the present study was to assess the effect of maternal periconceptional smoking (i.e. 1 year before through the first trimester of pregnancy) on the 2D:4D of children within The Maternal-Infant Research on Environmental Chemicals (MIREC) study...
May 23, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28529968/descriptive-statistics-and-regressions-of-2d-4d-and-educational-attainment-based-on-rlms-data
#11
John V C Nye, Maksym Bryukhanov, Sergiy Polyachenko
We document the descriptive statistics and detailed regression outputs for educational attainment and measured 2D:4D ratios, based on the RLMS data (20th round, conducted in 2011-2012). Regression analysis is conducted using STATA 13, gologit2 which is a special code for the generalized ordered logit regression in STATA environment. We provide graphs of differences in means of 2D:4D ratios by educational attainment. Information about the distribution of self-identified nationalities and fields of university degrees of respondents is presented...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28529769/une-surstructure-de-%C3%AE-ge-type-diamant-induite-par-un-dopage-d-anti-moine
#12
Adrian Gómez Herrero, Lamia Hammoudi, Mohammed Kars, Thierry Roisnel, L Carlos Otero-Diáz
Single crystals of anti-mony-doped germanium, Ge1-x Sb x+0.01 (x ≃ 0.0625), were grown by chemical transport reaction. The alloy crystallizes as a superstructure of diamond-type α-Ge. All atoms in the asymmetric unit lie on special positions and are characterized by strong covalent bonds. The anti-mony atoms substitute for one germanium atom at full occupancy at Wyckoff position 4a (site symmetry -43m), and are also at an adjacent tetra-hedral inter-stitial site with partially occupation (16%) at position 4c (or 4d) (site symmetry -43m)...
May 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28527753/asymmetry-and-empathy-higher-asymmetry-is-associated-with-lower-levels-of-mentalizing
#13
Colton B Christian, Azim F Shariff
People differ in their mentalizing abilities. Though past research suggests that individual differences in exposure to prenatal testosterone may be able to explain why some people excel at mentalizing, while others struggle, meta-analyses yield a null relationship between 2D:4D ratio (a proxy for prenatal testosterone) and mentalizing. Importantly, however, past research has not examined the asymmetrical differences between the digit ratios on the right and left hands. In the current work, we test whether the difference between the digit ratios of the left and right hands may function as a better predictor of mentalizing than digit ratio alone...
May 18, 2017: Early Human Development
https://www.readbyqxmd.com/read/28525845/novel-amidino-substituted-benzimidazole-and-benzothiazole-benzo-b-thieno-2-carboxamides-exert-strong-antiproliferative-and-dna-binding-properties
#14
Maja Cindrić, Samy Jambon, Anja Harej, Sabine Depauw, Marie-Hélène David-Cordonnier, Sandra Kraljević Pavelić, Grace Karminski-Zamola, Marijana Hranjec
Within this manuscript design, synthesis of novel 2-imidazolinyl substituted benzo[b]thieno-2-carboxamides bearing either benzimidazole or benzothiazole subunit and biological activity are presented and described. The antiproliferative activities were assessed in vitro on a panel of human cancer cell lines. Tested compounds showed moderate activity while cytotoxicity on normal fibroblasts was lower in comparison with 5-fluorouracile. The variations of 2-imidazolinyl substituent at heteroaromatic subunits in different positions led to different cytotoxic properties...
May 4, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28524198/isomer-dependent-fragmentation-dynamics-of-inner-shell-photoionized-difluoroiodobenzene
#15
Utuq Ablikim, Cédric Bomme, Evgeny Savelyev, Hui Xiong, Rajesh Kushawaha, Rebecca Boll, Kasra Amini, Timur Osipov, David Kilcoyne, Artem Rudenko, Nora Berrah, Daniel Rolles
The fragmentation dynamics of 2,6- and 3,5-difluoroiodobenzene after iodine 4d inner-shell photoionization with soft X-rays are studied using coincident electron and ion momentum imaging. By analyzing the momentum correlation between iodine and fluorine cations in three-fold ion coincidence events, we can distinguish the two isomers experimentally. Classical Coulomb explosion simulations are in overall agreement with the experimentally determined fragment ion kinetic energies and momentum correlations and point toward different fragmentation mechanisms and time scales...
May 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28522264/discovery-synthesis-and-structure-activity-relations-of-3-4-dihydro-1h-spiro-naphthalene-2-2-piperidin-1-ones-as-potassium-competitive-acid-blockers
#16
Toshihiro Imaeda, Koji Ono, Kazuo Nakai, Yasunobu Hori, Jun Matsukawa, Terufumi Takagi, Yasushi Fujioka, Naoki Tarui, Mitsuyo Kondo, Akio Imanishi, Nobuhiro Inatomi, Masahiro Kajino, Fumio Itoh, Haruyuki Nishida
With the aim to discover a gastric antisecretory agent more potent than the existing proton pump inhibitors, novel 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-one derivatives, which could occupy two important lipophilic pockets (described as LP-1 and LP-2) of H(+),K(+)-ATPase and can strongly bind to the K(+)-binding site, were designed based on a docking model. Among the compounds synthesized, compound 4d showed a strong H(+),K(+)-ATPase-inhibitory activity and a high stomach concentration in rats, resulting in potent inhibitory action on histamine-stimulated gastric acid secretion in rats...
May 6, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28521213/phylogenetic-analysis-of-an-epidemic-outbreak-of-acute-hepatitis-c-in-hiv-infected-patients-by-ultra-deep-pyrosequencing
#17
Noelia Caro-Pérez, María Martínez-Rebollar, Josep Gregori, Josep Quer, Patricia González, Martina Gambato, Neris García-González, Fernando González-Candelas, Josep Costa, Juan Ignacio Esteban, Josep Mallolas, Xavier Forns, Montse Laguno, Sofía Pérez-Del-Pulgar
BACKGROUND: The incidence of acute hepatitis C (AHC) among HIV-infected men who have sex with men (MSM) has increased significantly in the last 10 years. Several studies point to a social and sexual network of HIV-positive MSM that extends internationally. OBJECTIVES: The aim of our study was to investigate the dynamics of HCV transmission in an outbreak of AHC in HIV-infected MSM in Barcelona by ultra-deep pyrosequencing. STUDY DESIGN: Between 2008 and 2013, 113 cases of AHC in HIV-infected MSM were diagnosed in the Infectious Diseases Unit, Hospital Clínic, Barcelona...
May 10, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28514160/spatiotemporal-observation-of-electron-impact-dynamics-in-photovoltaic-materials-using-4d-electron-microscopy
#18
Basamat S Shaheen, Jingya Sun, Ding-Shyue Yang, Omar F Mohammed
Understanding light-triggered charge carrier dynamics near photovoltaic-material surfaces and at interfaces has been a key element and one of the major challenges for the development of real-world energy devices. Visualization of such dynamics information can be obtained using the one-of-a-kind methodology of scanning ultrafast electron microscopy (S-UEM). Here, we address the fundamental issue of how the thickness of the absorber layer may significantly affect the charge carrier dynamics on material surfaces...
May 17, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28513326/the-effects-of-blood-flow-restricted-electrostimulation-on-strength-hypertrophy
#19
Joshua Slysz, Jamie F Burr
CONTEXT: The combined effect of neuromuscular electrical muscle stimulation (NMES) and blood flow restriction (BFR) on muscle mass and strength has not been thoroughly investigated. OBJECTIVE: To examine the effects of combined and independent BFR and a low-intensity NMES on skeletal muscle adaptation. DESIGN: Exploratory Study. SETTING: Laboratory. PARTICIPANTS: Twenty recreationally active subjects...
May 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28509846/a-new-ergosterol-analog-a-new-bis-anthraquinone-and-anti-obesity-activity-of-anthraquinones-from-the-marine-sponge-associated-fungus-talaromyces-stipitatus-kufa-0207
#20
Jidapa Noinart, Suradet Buttachon, Tida Dethoup, Luís Gales, José A Pereira, Ralph Urbatzka, Sara Freitas, Michael Lee, Artur M S Silva, Madalena M M Pinto, Vítor Vasconcelos, Anake Kijjoa
A new ergosterol analog, talarosterone (1) and a new bis-anthraquinone derivative (3) were isolated, together with ten known compounds including palmitic acid, ergosta-4,6,8(14),22-tetraen-3-one, ergosterol-5,8-endoperoxide, cyathisterone (2), emodin (4a), questinol (4b), citreorosein (4c), fallacinol (4d), rheoemodin (4e) and secalonic acid A (5), from the ethyl acetate extract of the culture of the marine sponge-associated fungus Talaromyces stipitatus KUFA 0207. The structures of the new compounds were established based on extensive 1D and 2D spectral analysis, and in the case of talarosterone (1), the absolute configurations of its stereogenic carbons were determined by X-ray crystallographic analysis...
May 16, 2017: Marine Drugs
keyword
keyword
32384
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"