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https://www.readbyqxmd.com/read/29777842/nationally-representative-readmission-factors-in-patients-with-claudication-and-critical-limb-ischemia
#1
Rennier A Martinez, Michelle Shnayder, Joshua Parreco, Lukas Gaffney, Marcus Eby, Nicholas Cortolillo, Michael Lopez, Jack Zeltzer
INTRODUCTION: Hospital readmissions are not only associated with increased mortality, morbidity and costs but also, with current healthcare reform, tied to significant financial and administrative penalties. Some studies show that patients undergoing vascular surgery may have higher than average readmission rates. The recently released Nationwide Readmission Database (NRD) is the most comprehensive national source of readmission data, gathering discharge information from 22 geographically dispersed states, accounting for 51...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29776740/development-of-a-deformable-phantom-for-experimental-verification-of-4d-monte-carlo-simulations-in-a-deforming-anatomy
#2
Sara Gholampourkashi, Joanna E Cygler, Bernie Lavigne, Emily Heath
PURPOSE: To verify the accuracy of 4D Monte Carlo (MC) simulations, using the 4DdefDOSXYZnrc user code, in a deforming anatomy. We developed a tissue-equivalent and reproducible deformable lung phantom and evaluated 4D simulations of delivered dose to the phantom by comparing calculations against measurements. METHODS: A novel deformable phantom consisting of flexible foam, emulating lung tissue, inside a Lucite external body was constructed. A removable plug, containing an elastic tumor that can hold film and other dosimeters, was inserted in the phantom...
May 15, 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29775315/strain-mapping-of-two-dimensional-heterostructures-with-sub-picometer-precision
#3
Yimo Han, Kayla X Nguyen, Michael Cao, Paul D Cueva, Saien Xie, Mark W Tate, Prafull Purohit, Sol M Gruner, Jiwoong Park, David A Muller
Next-generation, atomically thin devices require in-plane, one-dimensional heterojunctions to electrically connect different two-dimensional (2D) materials. However, the lattice mismatch between most 2D materials leads to unavoidable strain, dislocations, or ripples, which can strongly affect their mechanical, optical, and electronic properties. We have developed an approach to map 2D heterojunction lattice and strain profiles with sub-picometer precision and the ability to identify dislocations and out-of-plane ripples...
May 18, 2018: Nano Letters
https://www.readbyqxmd.com/read/29772574/is-there-a-rationale-behind-pharmacotherapy-in-idiopathic-gynecomastia
#4
Anna Kasielska-Trojan, Marian Danilewicz, Bogusław Antoszewski
BACKGROUND/AIMS: The aim of this research was to analyze digit ratio in relation to estrogen receptor (ER) and progesterone receptor (PR) expression and to verify digit ratio (2D: 4D) as a marker of ER and PR overexpression in the male breast. METHODS: This study included 35 patients who underwent breast reduction due to the idiopathic form of gynecomastia. The average age of the studied individuals was 25.7 years (SD = 7.8). ER and PR expression was detected in breasts, and digit ratios were calculated in patients with idiopathic gynecomastia...
May 17, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29772060/nucleocytoplasmic-shuttling-the-ins-and-outs-of-quantitative-imaging
#5
Chris Molenaar, Kate L Weeks
Nucleocytoplasmic protein shuttling is integral to the transmission of signals between the nucleus and the cytoplasm. The nuclear/cytoplasmic distribution of proteins of interest can be determined via fluorescence microscopy, following labelling of the target protein with fluorophore-conjugated antibodies (immunofluorescence) or by tagging the target protein with an autofluorescent protein, such as green fluorescent protein (GFP). The latter enables live cell imaging, a powerful approach that precludes many of the artefacts associated with indirect immunofluorescence in fixed cells...
May 17, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29772057/a-4d-global-respiratory-motion-model-of-the-thorax-based-on-ct-images-a-proof-of-concept
#6
H Fayad, M Gilles, T Pan, D Visvikis
PURPOSE: Respiratory motion reduces the sensitivity and specificity of medical images especially in the thoracic and abdominal areas. It may affect applications such as cancer diagnostic imaging and/or radiation therapy (RT). Solutions to this issue include modelling of the respiratory motion in order to optimize both diagnostic and therapeutic protocols. Personalised motion modeling required patient specific four dimensional (4D) imaging which in the case of 4D computed tomography (4D CT) acquisition is associated with an increased dose...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29769576/motion-compensated-micro-ct-reconstruction-for-in-situ-analysis-of-dynamic-processes
#7
Thomas De Schryver, Manuel Dierick, Marjolein Heyndrickx, Jeroen Van Stappen, Marijn A Boone, Luc Van Hoorebeke, Matthieu N Boone
This work presents a framework to exploit the synergy between Digital Volume Correlation (DVC) and iterative CT reconstruction to enhance the quality of high-resolution dynamic X-ray CT (4D-µCT) and obtain quantitative results from the acquired dataset in the form of 3D strain maps which can be directly correlated to the material properties. Furthermore, we show that the developed framework is capable of strongly reducing motion artifacts even in a dataset containing a single 360° rotation.
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29768687/strict-correlation-of-homo-topology-and-magnetic-aromaticity-indices-in-d-block-metalloaromatics
#8
Michael Mauksch, Svetlana B Tsogoeva
Magnetic aromaticity and antiaromaticity of closed shell metalloaromatics with 4d transition metals (Nb, Tc, Rh) is strictly correlated with orbital topology (Möbius or Hückel) of their π-HOMO, investigated computationally with DFT methods. A surprisingly simple rule emerged: the metallacycle is aromatic (antiaromatic) when the number of π MO's is even and the π-HOMO is of Möbius (Hückel) topology - and vice versa when the number of π MO's is odd.
May 16, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29767988/experimentally-validated-structures-of-supported-metal-nanoclusters-on-mos-2
#9
Yongliang Shi, Boao Song, Reza Shahbazian-Yassar, Jin Zhao, Wissam A Saidi
In nanometer clusters (NCs) each atom counts. It is the specific arrangement of these atoms that determines the unique size-dependent functionalities of the NCs and hence their applications. Here we employ a self-consistent, combined theoretical and experimental approach to determine atom-by-atom the structures of supported Pt NCs on MoS2. The atomic structures are predicted using a genetic algorithm utilizing atomistic force fields and density functional theory, which are then validated using aberration-corrected scanning transmission electron microscopy...
May 16, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29765383/fish-based-markers-enable-identification-of-chromosomes-derived-from-tetraploid-thinopyrum-elongatum-in-hybrid-lines
#10
Daiyan Li, Tinghui Li, Yanli Wu, Xiaohui Zhang, Wei Zhu, Yi Wang, Jian Zeng, Lili Xu, Xing Fan, Lina Sha, Haiqin Zhang, Yonghong Zhou, Houyang Kang
Tetraploid Thinopyrum elongatum , which has superior abiotic stress tolerance characteristics, and exhibits resistance to stripe rust, powdery mildew, and Fusarium head blight, is a wild relative of wheat and a promising source of novel genes for wheat improvement. Currently, a high-resolution Fluorescence in situ hybridization (FISH) karyotype of tetraploid Th. elongatum is not available. To develop chromosome-specific FISH-based markers, the hexaploid Trititrigia 8801 and two accessions of tetraploid Th. elongatum were characterized by different repetitive sequences probes...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29763951/dynamic-4d-ct-angiography-for-guiding-transarterial-chemoembolization-impact-on-the-reduction-of-contrast-material-operator-radiation-exposure-catheter-consumption-and-diagnostic-confidence
#11
Moritz H Albrecht, Thomas J Vogl, Julian L Wichmann, Simon S Martin, Jan-Erik Scholtz, Sebastian Fischer, Renate M Hammerstingl, Marc Harth, Nour-Eldin A Nour-Eldin, Axel Thalhammer, Stephan Zangos, Ralf W Bauer
PURPOSE:  This study was carried out to investigate the impact of abdominal dynamic four-dimensional CT angiography (4D-CTA) for guiding transarterial chemoembolization (TACE) on the amount of contrast material used, operator radiation exposure, catheter consumption, and diagnostic confidence. MATERIALS AND METHODS:  Written consent was waived for this IRB-approved retrospective study. 29 patients (20 men; mean age: 65.7 ± 11.5 years) with malignant liver lesions underwent 4D-CTA, prior to initial TACE...
June 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29763494/expression-levels-of-semaphorins-3a-3b-4a-and-4d-on-human-peri-implantitis
#12
Marta Ferreira Bastos, Leonardo de Franco, Andressa Cristina Garcia Tebar, Gabriela Giro, Jamil Awad Shibli
PURPOSE: To evaluate the gene expression levels of semaphorins 3A, 3B, 4A, and 4D in both healthy and diseased implants. MATERIALS AND METHODS: Subjects with peri-implantitis presented clinical attachment loss, probing depth ≥ 5 mm, bleeding on probing and/or suppuration, and radiographic bone loss > 4 mm. Peri-implant tissue biopsy specimens were sampled for analysis of the mRNA expression levels for semaphorins 3A, 3B, 4A, and 4D. A real-time polymerase chain reaction was performed, and the gene expression levels of semaphorins in relation to the housekeeping gene were analyzed by using the nonparametric Mann-Whitney test (P < ...
May 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29761989/-super-resolution-reconstruction-for-lung-four-dimensional-computed-tomography-images-using-multi-model-gaussian-process-regression
#13
Shiting Fang, Tao Zhong, Jin Chen, Yu Zhang
Lung four dimensional computed tomography (4D-CT) can lead to accurate radiotherapy. However, for the safety of patients, the scan spacing of 4D-CT cannot be too small so that the inter-slice resolution of lung 4D-CT is low, and thus the coronal and sagittal images need to be interpolated to obtain high-resolution images. This paper presents a super-resolution reconstruction technique based on multi-model Gaussian process regression. We use the high-resolution transversal images and the corresponding low-resolution images as the training sets...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29760592/4d-modeling-in-a-gimbaled-linear-accelerator-by-using-gold-anchor-markers
#14
Hideharu Miura, Shuichi Ozawa, Takaaki Matsuura, Atsushi Kawakubo, Fumika Hosono, Kiyoshi Yamada, Yasushi Nagata
Purpose: The purpose of this study was to verify whether the dynamic tumor tracking (DTT) feature of a Vero4DRT system performs with 10-mm-long and 0.28 mm diameter gold anchor markers. Methods: Gold anchor markers with a length of 10 mm and a diameter of 0.28 mm were used. Gold anchor markers were injected with short and long types into bolus material. These markers were sandwiched by a Tough Water (TW) phantom in the bolus material. For the investigation of 4-dimensional (4D) modeling feasibility under various phantom thicknesses, the TW phantom was added at 2 cm intervals (in upper and lower each by 1 cm)...
May 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29760497/author-correction-white-matter-and-gray-matter-segmentation-in-4d-computed-tomography
#15
Rashindra Manniesing, Marcel T H Oei, Luuk J Oostveen, Jaime Melendez, Ewoud J Smit, Bram Platel, Clara I Sánchez, Frederick J A Meijer, Mathias Prokop, Bram van Ginneken
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29757473/iterative-inversion-of-deformation-vector-fields-with-feedback-control
#16
Abhishek Kumar Dubey, Alexandros-Stavros Iliopoulos, Xiaobai Sun, Fang-Fang Yin, Lei Ren
PURPOSE: Often, the inverse deformation vector field (DVF) is needed together with the corresponding forward DVF in 4D reconstruction and dose calculation, adaptive radiation therapy, and simultaneous deformable registration. This study aims at improving both accuracy and efficiency of iterative algorithms for DVF inversion, and advancing our understanding of divergence and latency conditions. METHOD: We introduce a framework of fixed-point iteration algorithms with active feedback control for DVF inversion...
May 14, 2018: Medical Physics
https://www.readbyqxmd.com/read/29757471/image-based-retrospective-4d-mri-in-external-beam-radiotherapy-a-comparative-study-with-a-digital-phantom
#17
Chiara Paganelli, John Kipritidis, Danny Lee, Guido Baroni, Paul Keall, Marco Riboldi
PURPOSE: Several image-based retrospective sorting methods of 4D Magnetic Resonance Imaging (4D MRI) have been proposed for respiratory motion reconstruction in external beam radiotherapy. However, the optimal strategy for providing accurate and artefact-free 4D MRI, ideally corresponding to an average breathing cycle, is not yet defined. This study presents a proactive comparison of three published image-based sorting methods, to define a groundwork for benchmarking in 4D MRI. METHODS: Three published 4D MRI methods were selected for image retrospective sorting; body area, mutual information and navigator slice...
May 14, 2018: Medical Physics
https://www.readbyqxmd.com/read/29757425/four-dimensional-flow-mri-analysis-of-cerebral-blood-flow-before-and-after-high-flow-extracranial-intracranial-bypass-surgery-with-internal-carotid-artery-ligation
#18
Erika Orita, Yasuo Murai, Tetsuro Sekine, Ryo Takagi, Yasuo Amano, Takahiro Ando, Kotomi Iwata, Makoto Obara, Shinichiro Kumita
BACKGROUND: The hemodynamic changes that occur after high-flow (extracranial-intracranial) EC-IC bypass surgery with internal carotid artery (ICA) ligation are not well known. OBJECTIVE: To assess blood flow changes after high-flow EC-IC bypass with ICA ligation by time-resolved 3-dimensional phase-contrast (4D Flow) magnetic resonance imaging (MRI). METHODS: We enrolled 11 patients who underwent high-flow EC-IC bypass. 4D Flow MRI was performed before and after surgery to quantify the blood flow volume (BFV) of the ipsilateral ICA (BFViICA), bypass artery (BFVbypass), contralateral ICA (BFVcICA), and basilar artery (BFVBA)...
May 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29756584/4d-qsar-study-of-some-pyrazole-pyridine-carboxylic-acid-derivatives-by-electron-conformational-genetic-algorithm-method
#19
Burak Tuzun, Sevtap Caglar Yavuz, Nazmiye Sabanci, Emin Saripinar
In the present work, pharmacophore identification and biological activity prediction for 86 pyrazole pyridine carboxylic acid derivatives were made using the electron conformational genetic algorithm approach which was introduced as a 4D-QSAR analysis by us in recent years. In the light of the data obtained from quantum chemical calculations at HF/6-311 G** level, the electron conformational matrices of congruity (ECMC) were constructed by EMRE software. Comparing the matrices, electron conformational submatrix of activity (ECSA, Pha) was revealed that are common for these compounds within a minimum tolerance...
May 13, 2018: Current Computer-aided Drug Design
https://www.readbyqxmd.com/read/29756583/4d-qsar-studies-using-a-new-descriptor-of-the-klopman-index-antibacterial-activities-of-sulfone-derivatives-containing-1-3-4-oxadiazole-moiety-based-on-mcet-model
#20
Yahya Guzel, Ertugrul Aslan, Burcin Turkmenoglu, E Mesut Su
In this paper, we have introduced a new atomic descriptor with Klopman index to determine the local reactive sites of the molecular systems during electrophilic, nucleophilic attacks. This index, similar to other local reactivity descriptors but more advanced, has been used as a realistic descriptor to discover new aspects of molecular structure. Nonlinear least squares (NLLS) methods to define the parameters maximizing the fit between the observed points and the computed simulation results were performed according to the Levenberg-Marquardt (LM) algorithm...
May 13, 2018: Current Computer-aided Drug Design
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