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https://www.readbyqxmd.com/read/29785635/self-monitoring-physical-activity-with-a-smartphone-application-in-cancer-patients-a-randomized-feasibility-study-smart-trial
#1
Harm L Ormel, Gabriela G F van der Schoot, Nico-Derk L Westerink, Wim J Sluiter, Jourik A Gietema, Annemiek M E Walenkamp
PURPOSE: Evidence accumulates that an active lifestyle positively influences cancer treatment outcome. A "smartphone application" (app) such as "RunKeeper," to self-monitor physical activity (PA) might be helpful. This study aimed to examine whether using RunKeeper to increase self-reported PA is feasible in cancer patients and to evaluate patients' opinion about using RunKeeper in a 12-week program. METHODS: Adult patients (n = 32), diagnosed with cancer, were randomized between usual care (n = 16) or a 12-week intervention with instructions to self-monitor PA with RunKeeper (n = 16)...
May 21, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29779808/is-multi-level-marketing-of-nutrition-supplements-a-legal-and-an-ethical-practice
#2
Diana Cardenas, Vanessa Fuchs-Tarlovsky
BACKGROUND: Multi-level marketing (MLM) of nutrition products has experienced dramatic growth in recent decades. 'Wellness' is the second most popular niche in the MLM industry and represents 35% of sales among all the products in 2016. This category includes dietary supplements, weight management and sports nutrition products. The aim of this paper is to analyse whether this practice is legal and ethical. METHODS: An analysis of available documentary information about the legal aspects of Multi-level marketing business was performed...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779227/risk-profile-of-young-people-admitted-to-hospital-for-suicidal-behaviour-in-melbourne-australia
#3
Rohan Borschmann, Patrick Stark, Chidambaram Prakash, Susan M Sawyer
AIM: Self-harm and suicidal behaviour is most prevalent during adolescence, but little is known about the risk profile of adolescents admitted to hospital for suicidal behaviour. Young people who self-harm are at an increased risk of mortality compared to those who do not self-harm; adolescents admitted to hospital for suicidal behaviour are particularly at risk. The aim of this study was to generate a risk profile of adolescents admitted to hospital with suicidal behaviour. METHODS: We conducted a 12-month retrospective audit of adolescent admissions to the mental health inpatient unit at a tertiary children's hospital in Melbourne, Australia...
May 20, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29778017/the-preconception-care-experiences-of-women-with-epilepsy-on-sodium-valproate
#4
Lorna Lawther, Helen Dolk, Marlene Sinclair, Jim Morrow
PURPOSE: To understand the preconception experiences of women with epilepsy who have been taking the teratogenic drug valproate. METHODS: Seven women were recruited, three from a preconception clinic and four from an antenatal clinic in a region of the UK. All had taken valproate preconceptionally. Three preconception clinic encounters were observed and audio-recorded. Interviews with all women were analysed using Interpretative Phenomenological Analysis (IPA). RESULTS: Women experienced a "trajectory of balance"...
May 16, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29772910/qualitative-assessment-of-smoke-free-policy-implementation-in-low-income-housing-enhancing-resident-compliance
#5
Jodi Anthony, Roberta Goldman, Vaughan W Rees, Rochelle L Frounfelker, Jessica Davine, Robyn R Keske, Daniel R Brooks, Alan C Geller
PURPOSE: As public housing agencies and other low-income housing providers adopt smoke-free policies, data are needed to inform implementation approaches that support compliance. DESIGN: Focused ethnography used including qualitative interviews with staff, focus groups with residents, and property observations. SETTING: Four low-income housing properties in Massachusetts, 12 months postpolicy adoption. PARTICIPANTS: Individual interviews (n = 17) with property staff (managers, resident service coordinators, maintenance, security, and administrators) and focus groups with resident smokers (n = 28) and nonsmokers (n = 47)...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29770101/resources-to-address-stigma-related-to-sexuality-substance-use-and-sexually-transmitted-and-blood-borne-infections
#6
R MacLean
Background: Stigma is widely recognized as a significant barrier to the prevention, management and treatment of sexually transmitted and blood-borne infections (STBBIs) in Canada. Despite major advances in STBBI prevention and treatment, and global efforts to reduce stigma, people living with or affected by STBBIs continue to experience stigma within health and social service settings in Canada. Objective: To describe the development, content and evaluation of knowledge translation resources and training workshops designed to equip health and social service professionals with the knowledge and skills needed to provide more respectful and inclusive sexual health, harm reduction and STBBI services...
February 1, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29768223/nano-biosensor-based-on-reduced-graphene-oxide-and-gold-nanoparticles-for-detection-of-phenylketonuria-associated-dna-mutation
#7
Seyed Morteza Seifati, Navid Nasirizadeh, Mostafa Azimzadeh
Phenylketonuria (PKU)-associated DNA mutation in newborn children can be harmful to his health and early detection is the best way to inhibit consequences. A novel electrochemical nano-biosensor was developed for PKU detection, based on signal amplification using nanomaterials, e.g. gold nanoparticles (AuNPs) decorated on the reduced graphene oxide sheet on the screen-printed carbon electrode. The fabrication steps were checked by field emission scanning electron microscope imaging as well as cyclic voltammetry analysis...
June 2018: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29767281/hiv-risk-among-displaced-adolescent-girls-in-ethiopia-the-role-of-gender-attitudes-and-self-esteem
#8
Laura Gauer Bermudez, Gary Yu, Lily Lu, Kathryn Falb, Jennate Eoomkham, Gizman Abdella, Lindsay Stark
Adolescent girls in sub-Saharan Africa have been deemed one of the most critical populations to address in the campaign for an HIV-free generation. Experiences of intimate partner violence (IPV), harmful gender norms, diminished personal agency, and age-disparate sex have been identified as factors in the increasing rate of new infections among this population. Using baseline data from a cluster-randomized controlled trial in three refugee camps in Benishangul-Gumuz Regional State in Ethiopia, our study quantitatively examined the associations between HIV risk factors, attitudes on gender inequality, IPV acceptability, and self-esteem for female adolescent refugees primarily from Sudan and South Sudan (n = 919)...
May 16, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29766842/continuous-low-dose-antibiotic-prophylaxis-to-prevent-urinary-tract-infection-in-adults-who-perform-clean-intermittent-self-catheterisation-the-antic-rct
#9
Robert Pickard, Thomas Chadwick, Yemi Oluboyede, Catherine Brennand, Alexander von Wilamowitz-Moellendorff, Doreen McClurg, Jennifer Wilkinson, Laura Ternent, Holly Fisher, Katherine Walton, Elaine McColl, Luke Vale, Ruth Wood, Mohamed Abdel-Fattah, Paul Hilton, Mandy Fader, Simon Harrison, James Larcombe, Paul Little, Anthony Timoney, James N'Dow, Heather Armstrong, Nicola Morris, Kerry Walker, Nikesh Thiruchelvam
BACKGROUND: People carrying out clean intermittent self-catheterisation (CISC) to empty their bladder often suffer repeated urinary tract infections (UTIs). Continuous once-daily, low-dose antibiotic treatment (antibiotic prophylaxis) is commonly advised but knowledge of its effectiveness is lacking. OBJECTIVE: To assess the benefit, harms and cost-effectiveness of antibiotic prophylaxis to prevent UTIs in people who perform CISC. DESIGN: Parallel-group, open-label, patient-randomised 12-month trial of allocated intervention with 3-monthly follow-up...
May 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29766353/how-ethical-is-our-current-delivery-of-care-to-patients-with-severe-and-complicated-obesity
#10
REVIEW
Hilary Craig, Carel le Roux, Fiona Keogh, Francis M Finucane
Despite overwhelming evidence that bariatric interventions reduce morbidity and mortality and are cost-effective, access for affected patients is limited. We sought to describe the extent to which health policy makers and publically funded health services have an ethical obligation to provide bariatric care. We conducted a narrative review of the literature pertaining to the efficacy, safety, and cost-effectiveness of bariatric surgical interventions, in the context of the core principles of medical ethics...
May 15, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29766128/a-multi-decade-joinpoint-analysis-of-firearm-injury-severity
#11
Bindu Kalesan, Yi Zuo, Ziming Xuan, Michael B Siegel, Jeffrey Fagan, Charles Branas, Sandro Galea
Background: Non-fatal firearm injuries constitute approximately 70% of all firearm trauma injuries in the United States. Patterns of severity of these injuries are poorly understood. We analyzed the overall, age-, sex- and intent-specific temporal trends in the injury severity of firearm hospitalizations from 1993 to 2014. Methods: We assessed temporal trends in the severity of patients hospitalized for firearm using Nationwide Inpatient Sample (NIS) data over a 22 year period...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29765428/autophagy-in-stem-cell-biology-a-perspective-on-stem-cell-self-renewal-and-differentiation
#12
REVIEW
Xihang Chen, Yunfan He, Feng Lu
Autophagy is a highly conserved cellular process that degrades modified, surplus, or harmful cytoplasmic components by sequestering them in autophagosomes which then fuses with the lysosome for degradation. As a major intracellular degradation and recycling pathway, autophagy is crucial for maintaining cellular homeostasis, as well as for remodeling during normal development. Impairment of this process has been implicated in various diseases, in the pathogenic response to bacterial and viral infections, and in aging...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29764882/postnatal-depression-and-intimate-partner-violence-a-nationwide-clinic-based-cross-sectional-study-in-malaysia
#13
Noor Ani Ahmad, Umi Adzlin Silim, Azriman Rosman, Majdah Mohamed, Ying Ying Chan, Noraida Mohd Kasim, Muslimah Yusof, Mohamad Aznuddin Abd Razak, Maisarah Omar, Fazly Azry Abdul Aziz, Rasidah Jamaluddin, Fatanah Ismail, Nurashikin Ibrahim, Tahir Aris
INTRODUCTION: An estimated 13% of women in the postnatal period suffer from postnatal depression (PND) worldwide. In addition to underprivileged women, women who are exposed to violence are at higher risk of PND. This study aimed to investigate the relationship between intimate partner violence (IPV) and PND in Malaysia. METHODS: This survey was conducted as a nationwide cross-sectional study using a cluster sampling design. Probable PND was assessed using a self-administered Edinburgh Postnatal Depression Scale (EPDS)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29763434/ibuprofen-versus-pivmecillinam-for-uncomplicated-urinary-tract-infection-in-women-a-double-blind-randomized-non-inferiority-trial
#14
Ingvild Vik, Marianne Bollestad, Nils Grude, Anders Bærheim, Eivind Damsgaard, Thomas Neumark, Lars Bjerrum, Gloria Cordoba, Inge Christoffer Olsen, Morten Lindbæk
BACKGROUND: Although uncomplicated urinary tract infections (UTIs) are often self-limiting, most patients will be prescribed antibiotic treatment. We assessed whether treatment with ibuprofen was non-inferior to pivmecillinam in achieving symptomatic resolution by day 4, with a non-inferiority margin of 10%. METHODS AND FINDINGS: This was a randomized, controlled, double-blind non-inferiority trial. We recruited patients from 16 sites in a general practice setting in Norway, Sweden, and Denmark...
May 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29762767/concerns-and-help-seeking-among-patients-using-opioids-for-management-of-chronic-noncancer-pain
#15
Briony Larance, Gabrielle Campbell, Teleri Moore, Suzanne Nielsen, Raimondo Bruno, Nicholas Lintzeris, Milton Cohen, Wayne Hall, Richard Mattick, Courtney O'Donnell, Louisa Degenhardt
Background: The safety and efficacy of long-term opioid treatment for chronic noncancer pain (CNCP) remains controversial. This study examined whether patients who report problematic opioid use sought help and/or perceived barriers to help-seeking. Methods: Data were collected from 1,086 people prescribed opioids for CNCP via a large prospective cohort called the Pain and Opioids IN Treatment (POINT) study. Patients' characteristics and help-seeking were examined according to scores on the Prescribed Opioids Difficulties Scale (PODS)...
May 11, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29760878/chiropractic-treatment-including-instrument-assisted-manipulation-for-non-specific-dizziness-and-neck-pain-in-community-dwelling-older-people-a-feasibility-randomised-sham-controlled-trial
#16
Julie C Kendall, Simon D French, Jan Hartvigsen, Michael F Azari
Background: Dizziness in older people is a risk factor for falls. Neck pain is associated with dizziness and responds favourably to neck manipulation. However, it is unknown if chiropractic intervention including instrument-assisted manipulation of the neck in older people with neck pain can also improve dizziness. Methods: This parallel two-arm pilot trial was conducted in Melbourne, Australia over nine months (October 2015 to June 2016). Participants aged 65-85 years, with self-reported chronic neck pain and dizziness, were recruited from the general public through advertisements in local community newspapers and via Facebook...
2018: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29760300/workaholism-and-negative-work-related-incidents-among-nurses
#17
Cecilie Schou Andreassen, Ståle Pallesen, Bente E Moen, Bjørn Bjorvatn, Siri Waage, Wilmar B Schaufeli
The present study comprised 1,781 nurses who participated in an investigation about working conditions, sleep, and health. They answered a questionnaire about age, sex, marital status, children living at home, work hours per week, number of night shifts last year, and total sleep duration and that also included a validated instrument assessing workaholism. In addition, they were asked to report on eight items concerning negative work-related incidents (dozed off at work, dozed while driving, harmed or nearly harmed self, harmed or nearly harmed patients/others, and harmed or nearly harmed equipment)...
May 15, 2018: Industrial Health
https://www.readbyqxmd.com/read/29759590/reasons-for-non-participation-in-supplemental-population-based-mri-breast-screening-for-women-with-extremely-dense-breasts
#18
S V de Lange, M F Bakker, E M Monninkhof, P H M Peeters, P K de Koekkoek-Doll, R M Mann, M J C M Rutten, R H C Bisschops, J Veltman, K M Duvivier, M B I Lobbes, H J de Koning, N Karssemeijer, R M Pijnappel, W B Veldhuis, C H van Gils
AIM: To determine the willingness of women with extremely dense breasts to undergo breast cancer screening with magnetic resonance imaging (MRI) in a research setting, and to examine reasons for women to participate or not. MATERIALS AND METHODS: Between 2011 and 2015, 8,061 women (50-75 years) were invited for supplemental MRI as part of the Dense Tissue and Early Breast Neoplasm Screening (DENSE) trial (ClinicalTrials.gov Identifier: NCT01315015), after a negative screening mammography in the national population-based mammography screening programme...
May 11, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29757962/the-relationship-between-shoe-fitting-and-foot-health-of-persons-with-down-syndrome-a-case-control-study
#19
César Calvo-Lobo, Ana Ramos García, Marta Elena Losa Iglesias, Daniel López-López, David Rodríguez-Sanz, Carlos Romero-Morales, Ricardo Becerro-de-Bengoa-Vallejo
Background : Down syndrome is the most common chromosomal abnormality and a cause of intellectual disability. It is also associated with orthopaedic and musculoskeletal problems of the locomotive apparatus, especially of the feet. These problems are believed to have a harmful effect on health, social functioning, and mobility. In addition, these persons generally don't have access to podiatric health services, even when their foot problems are well known, because of limited access to healthcare facilities. The goal of our research was to evaluate and compare the foot health status of study participants with and without Down syndrome and to determine whether inadequate footwear is being used with normalized reference values...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29756803/attitude-toward-own-aging-as-a-risk-factor-for-cognitive-disorder-in-old-age-12-year-evidence-from-the-ilse-study
#20
Jelena S Siebert, Hans-Werner Wahl, Christina Degen, Johannes Schröder
Previous research has demonstrated the harmful impact of subjective aging processes (e.g., negative age self-stereotyping) on normal cognitive aging in different domains of cognitive functioning, such as memory, executive function, and fluid abilities. Recently, subjective aging has also been linked to important biomarkers of Alzheimer's disease (AD) and dementia-related outcomes, indicating associations with pathological cognitive aging. With data from the Interdisciplinary Longitudinal Study of Adult Development and Aging (ILSE), the present study extends this research by examining the long-term effect of attitude toward own aging (ATOA) on expert-based clinical diagnosis of mild cognitive impairment (MCI) and AD in old age...
May 2018: Psychology and Aging
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