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https://www.readbyqxmd.com/read/28918588/a-practical-approach-to-managing-hypoactive-sexual-desire-disorder-in-women-with-diabetes
#1
REVIEW
Charmaine Rochester-Eyeguokan, Lisa Meade
Female sexual dysfunction (FSD) is highly prevalent in women with diabetes mellitus (DM), yet it remains unaddressed, undiagnosed, and untreated. Hypoactive sexual desire disorder (HSDD) is the most common complaint among women with FSD, but there is a paucity of research into its multifactorial etiology. Flibanserin is the only therapy approved by the US Food and Drug Administration for treating acquired, generalized HSDD in premenopausal women. Women with DM diagnosed with HSDD may require a multidisciplinary approach for optimal management...
September 16, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28917550/antidiabetic-potential-of-methanolic-and-flavonoid-rich-leaf-extracts-of-synsepalum-dulcificum-in-type-2-diabetic-rats
#2
Olabisi T Obafemi, Clement A Akinmoladun, Tolulope M Olaleye, Stephen O Agboade, Amos A Onasanya
BACKGROUND: Synsepalum dulcificum is a plant indigenous to West Africa. The fruit is used to modify taste of foods to sweetness. OBJECTIVES: This study aims to investigate the antidiabetic potentials of both methanolic and flavonoid-rich leaf extracts of S. dulcificum (MSD and FSD respectively) in type 2 diabetic Wistar albino rats. MATERIALS AND METHODS: Sixty three rats were randomly distributed into nine groups of seven animals each with group 1 serving as the normal control...
September 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28885410/distressing-sexual-function-at-midlife-unmet-needs-practical-diagnoses-and-available-treatments
#3
James A Simon, Vanessa A Lukas
Female sexual dysfunction (FSD) is characterized as chronic sexual symptoms that manifest with personal distress in the domains of desire, arousal, orgasm, and pain. Extensive epidemiologic evidence estimates that almost 50% of perimenopausal and postmenopausal women experience FSD. Screening for FSD is not readily conducted and patient-physician discussion of sexuality is limited by the lack of physician training on the topic and by the patient-held belief that sexual issues are not medical in nature. The purpose of this commentary is to provide clinicians with a framework to approach the discussion of FSD, to clinically identify FSD through patient symptoms and physical signs, and to manage FSD in perimenopausal and postmenopausal patients with the available U...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28854947/effect-of-female-genital-mutilation-cutting-types-i-and-ii-on-sexual-function-case-controlled-study
#4
Sahar A Ismail, Ahmad M Abbas, Dina Habib, Hanan Morsy, Medhat A Saleh, Mustafa Bahloul
BACKGROUND: The existing literature is contradictory regarding effects of female genital mutilation/cutting (FGM/C) on sexual functions. The aim of this study was to explore the impact of type I and II FGM/C on sexual function of Egyptian women. METHODS: We recruited 197 cut women and 197 control women from those visiting Assiut University hospitals for different reasons. We asked each woman to fill the Arabic female sexual function index (FSFI) (a self reported 19-item questionnaire assessing the main domains of female sexual function)...
August 30, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28843867/prevalence-of-sexual-dysfunction-in-infertile-versus-fertile-couples
#5
Amir A Gabr, Eman F Omran, Ahmed A Abdallah, Mohamed M Kotb, Eman Z Farid, Amira S Dieb, Doaa S Belal
OBJECTIVES: The primary aim of this study was to test the hypothesis that sexual dysfunction is higher in infertile females in relation to normal healthy women through comparing total and sexual domains scores in both groups. The secondary objectives were: to determine factors affecting occurrence of female sexual dysfunction (FSD) in all sample and to determine factors affecting the different sexual domain scores within the infertile group. STUDY DESIGN: This cross sectional study was done at Cairo University Hospital...
August 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28827036/urinary-incontinence-and-associated-female-sexual-dysfunction
#6
REVIEW
Erin R Duralde, Tami S Rowen
INTRODUCTION: Urinary incontinence (UI) and sexual dysfunction are common conditions often undiagnosed and untreated in women and are associated with decreased quality of life. AIM: To evaluate the relation between UI and female sexual dysfunction (FSD), considering incontinence type and the psychosocial and physiologic aspects of sexual function. METHODS: PubMed search of terms related to UI and FSD from 1979 to 2016 generated 603 published references, of which 26 were included...
August 18, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28813300/sexual-dysfunction-and-relationship-stress-how-does-this-association-vary-for-men-and-women
#7
REVIEW
Marita P McCabe, Catherine Connaughton
This paper examines the association between relationship stress and sexual dysfunction. The results demonstrated a strong association between female sexual dysfunction (FSD) and relationship stress, and between male sexual dysfunction (MSD) and relationship stress among their female partners. No studies examined the association between FSD and relationship stress of male partners. Treatment for MSD was associated with improved relationship stress for female partners, but no studies were located that examined this association for treatment of FSD...
February 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28700039/sexual-dysfunction-in-females-with-depression-a-cross-sectional-study
#8
Krishnankutty Sreelakshmy, Rajmohan Velayudhan, Deepak Kuriakose, Rema Nair
Introduction: Female sexual dysfunction (FSD) in depression albeit common is strikingly understudied. The condition, if addressed properly, can be readily cured, improving the quality of life of the patient. Methods: A consecutive sample of drug-naïve married female patients with depression was assessed. Depression was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Depression severity was assessed using the Hamilton Depression Rating Scale (HAM-D), and sexual dysfunction, the Female Sexual Function Index (FSFI)...
April 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28697019/outcome-differences-in-adolescent-blunt-severe-polytrauma-patients-managed-at-pediatric-versus-adult-trauma-centers
#9
Amelia T Rogers, Brian W Gross, Alan D Cook, Cole D Rinehart, Caitlin A Lynch, Eric H Bradburn, Colin C Heinle, Frederick B Rogers
BACKGROUND: Previous research suggests adolescent trauma patients can be managed equally effectively at pediatric and adult trauma centers. We sought to determine whether this association would be upheld for adolescent severe polytrauma patients. We hypothesized that no difference in adjusted outcomes would be observed between pediatric trauma centers (PTC) and adult trauma centers (ATC) for this population. METHODS: All severely injured adolescent (aged 12-17 years) polytrauma patients were extracted from the Pennsylvania Trauma Outcomes Study database from 2003-2015...
July 8, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28677142/assessment-of-sexually-related-personal-distress-accompanying-premenopausal-sexual-dysfunction-with-an-arabic-version-of-the-female-sexual-distress-scale
#10
Magdy R Ahmed, Mohamed M Shaaban, Heba K Meky
OBJECTIVE: To assess sexually related personal distress among premenopausal women with female sexual dysfunction (FSD) via a validated Arabic version of the Female Sexual Distress Scale (FSDS). METHODS: A cross-sectional study was conducted among women attending Suez Canal University Hospital, Egypt, between May 2015 and July 2016. In a pilot study to evaluate test-retest reliability and internal consistency, 42 sexually active premenopausal women (aged ≥20 years) completed the Arabic FSDS at recruitment and 2 weeks later...
July 5, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28660561/hormonal-effect-on-the-relationship-between-migraine-and-female-sexual-dysfunction
#11
Vasfiye Burcu Dogan, Hediye Dagdeviren, Ahmet Dirican, Ayten Ceyhan Dirican, Nurhan Kaya Tutar, Vidan Ayse Yayla, Hüseyin Cengiz
It is not a well-established finding in migraine that female sexual dysfunction (FSD) emerging as a natural course of disease, as a result of accompanying depression/anxiety, or an underlying endocrinological abnormality. Our aim is evaluating the relationship among frequency and severity of migraine, FSD, depression, anxiety, and related hormones in migrainous women. We examined 80 migrainous female and 62 controls cross sectionally. Beck Depression and Anxiety Inventories, Female Sexual Dysfunction Inventory, Migraine Disability Assessment Test, and hormonal analysis were done...
June 28, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28639335/a-systematic-review-on-identifying-risk-factors-associated-with-early-sexual-debut-and-coerced-sex-among-adolescents-and-young-people-in-communities
#12
REVIEW
Regina Lai Tong Lee, Alice Yuen Loke, Tsz Man Tommy Hung, Howard Sobel
AIM: To review literature on identifying the risk factors associated with early sexual coerced debut with the aim to facilitate the health care workers' planning of relevant health services to improve intervention strategies for delaying of early coerced sexual debut or forced sexual debut (CSD/FSD) in the communities. BACKGROUND: Identifying the risk factors associated with coercion at first sex is crucial for developing appropriate sexual and reproductive health information and health promotion in response...
June 21, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28632082/the-%C3%AE-helix-alignment-of-proteins-in-water-solution-toward-a-high-frequency-electromagnetic-field-a-ftir-spectroscopy-study
#13
Emanuele Calabrò, Salvatore Magazù
The aim of this article was to study the effects of mobile phone electromagnetic waves at 1750 MHz on the Amide I and Amide II vibration bands of some proteins in bidistilled water solution by means of Fourier transform infrared (FTIR) spectroscopy and Fourier self-deconvolution (FSD) analysis. The proteins that were used for the experiment were hemoglobin, myoglobin, bovine serum albumin and lysozyme. The exposure system consisted of microwaves emitted by an operational mobile phone at the frequency at 1750 MHz at the average power density of 1 W/m(2)...
June 20, 2017: Electromagnetic Biology and Medicine
https://www.readbyqxmd.com/read/28622875/does-the-severity-of-overactive-bladder-symptoms-correlate-with-risk-for-female-sexual-dysfunction
#14
Cássia Raquel Teatin Juliato, Iane Glauce Ribeiro Melotti, Luiz Carlos Santos Junior, Luiz Gustavo Oliveira Britto, Cássio Luiz Zanettini Riccetto
BACKGROUND: Several studies have associated overactive bladder (OAB) with female sexual dysfunction (FSD); however, there are no reports using a quantitative approach to measure OAB severity and to relate OAB to the risk of FSD. AIM: To evaluate women with OAB and to correlate the severity of their urinary symptoms with their sexual function. METHODS: This cross-sectional study included 267 women older than 18 years with untreated OAB. All subjects completed the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and the Female Sexual Function Index (FSFI)...
June 13, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28617103/effects-of-mindfulness-based-therapies-for-female-sexual-dysfunction-a-meta-analytic-review
#15
Kyle R Stephenson, Jonathan Kerth
Mindfulness-based therapy (MBT) represents a potentially efficacious treatment for female sexual dysfunction (FSD). A number of recent trials assessing MBT for FSD have been published, but we are aware of no existing meta-analysis synthesizing these results. We conducted a literature review to identify all published trials of MBT for FSD. References of retrieved studies were searched and key authors were contacted with requests for complete but unpublished trials. Eleven trials, including a total of 449 participants, were identified...
June 15, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28584199/prevalence-and-factors-associated-with-female-sexual-dysfunction-in-beijing-china
#16
Wen-Jia Lou, Bo Chen, Lan Zhu, Shao-Mei Han, Tao Xu, Jing-He Lang, Lei Zhang
BACKGROUND: Female sexual dysfunction (FSD) is a highly prevalent and often underestimated problem. However, large-scale, population-based epidemiological surveys of FSD are scarce in China. The present study was conducted to evaluate the prevalence and the potential risk factors of FSD across a selection of social groups in Beijing, China, based on the Female Sexual Function Index (FSFI). METHODS: A cross-sectional study based on the multiple-stage cluster sampling was performed with adult women throughout the Dongcheng and Shunyi districts of Beijing...
June 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28548089/finding-multiple-reaction-pathways-via-global-optimization-of-action
#17
Juyong Lee, In-Ho Lee, InSuk Joung, Jooyoung Lee, Bernard R Brooks
Global searching for reaction pathways is a long-standing challenge in computational chemistry and biology. Most existing approaches perform only local searches due to computational complexity. Here we present a computational approach, Action-CSA, to find multiple diverse reaction pathways connecting fixed initial and final states through global optimization of the Onsager-Machlup action using the conformational space annealing (CSA) method. Action-CSA successfully overcomes large energy barriers via crossovers and mutations of pathways and finds all possible pathways of small systems without initial guesses on pathways...
May 26, 2017: Nature Communications
https://www.readbyqxmd.com/read/28492147/female-sexual-dysfunction-in-the-late-postpartum-period-among-women-with-previous-gestational-diabetes-mellitus
#18
Mehmet Akif Sargin, Murat Yassa, Bilge Dogan Taymur, Bulent Taymur, Gizem Akca, Niyazi Tug
OBJECTIVE: To compare the status of female sexual dysfunction (FSD) between women with a history of previous gestational diabetes mellitus (GDM) and those with follow-up of a healthy pregnancy, using the female sexual function index (FSFI) questionnaire. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Department of Obstetrics and Gynecology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey, from September to December 2015...
April 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28470948/using-transmission-kikuchi-diffraction-to-characterise-%C3%AE-variants-in-an-%C3%AE-%C3%AE-titanium-alloy
#19
V Tong, S Joseph, A K Ackerman, D Dye, T B Britton
Two phase titanium alloys are important for high-performance engineering components, such as aeroengine discs. The microstructures of these alloys are tailored during thermomechanical processing to precisely control phase fractions, morphology and crystallographic orientations. In bimodal two phase (α + β) Ti-6Al-2Sn-4Zr-2Mo (Ti-6242) alloys there are often three microstructural lengthscales to consider: large (∼10 μm) equiaxed primary α; >200 nm thick plate α with a basketweave morphology; and very fine scaled (<50 nm plate thickness) secondary α that grows between the larger α plates surrounded by retained β...
September 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28470298/fluorescence-enhancement-and-pka-shift-of-a-rho-kinase-inhibitor-by-a-synthetic-receptor
#20
Hang Yin, Linmin Chen, Binrui Yang, David Bardelang, Chunming Wang, Simon M Y Lee, Ruibing Wang
Fasudil (FSD), a selective rho kinase (ROCK) inhibitor, was found to form 1 : 1 host-guest inclusion complexes with a synthetic macrocyclic receptor, cucurbit[7]uril (CB[7]), in aqueous solutions, as evidenced by (1)H NMR, photoluminescence and UV-visible spectroscopic titrations, isothermal titration calorimetry (ITC) titration, and electrospray ionization (ESI) mass spectrometry, as well as density functional theory (DFT) molecular modeling. Upon encapsulation, whereas the UV-vis absorbance of FSD experienced a moderate decrease and bathochromic shift, the fluorescence intensity of FSD at 354 nm was dramatically enhanced for up to 69-fold at neutral pH, which could potentially be applied in fluorescent tracking of the drug delivery and release...
May 23, 2017: Organic & Biomolecular Chemistry
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