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SEER colorectal

Yi-Bo Cai, Hai-Yan Chen, Jin-Jie He, Ye-Ting Hu, Qi Yang, Liu-Bo Chen, Qian Xiao, Ke-Feng Ding
BACKGROUND: Primary colorectal lymphoma (PCL) is a rare colorectal malignancy. The standard treatment and prognostic factors of PCL remain unexplored. Therefore, a large population-based study should be conducted to provide a detailed review of this disease. METHODS: We extracted the data of eligible patients with PCL registered in the SEER database from 1973 to 2011. All statistical analyses were performed using SPSS 19.0. RESULTS: A total of 2050 (61...
September 29, 2016: Oncotarget
Christine W Duarte, Adam W Black, F Lee Lucas, Calvin P H Vary
PURPOSE: Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder characterized by deficiency in endoglin, an angiogenic protein. We previously showed that HHT, in which systemic endoglin expression is reduced, was associated with better survival outcomes in cancer patients (Duarte et al. in Cancer Epidemiol Biomarkers Prev 23:117-125, 2014). Here, we evaluated whether HHT was associated with reduced cancer incidence. METHODS: A matched case-control analysis using SEER Medicare was conducted to evaluate the effect of HHT on diagnosis with breast, colorectal, lung, or prostate cancer between 2000 and 2007 (n = 633,162)...
September 16, 2016: Journal of Cancer Research and Clinical Oncology
Caitlin C Murphy, Robert S Sandler, Hanna K Sanoff, Y Claire Yang, Jennifer L Lund, John A Baron
BACKGROUND & AIMS: The incidence of colorectal cancer (CRC) in the U.S. is increasing among adults younger than age 50 years, but incidence has decreased among older populations after population-based screening was recommended in the late 1980s. Blacks have higher incidence than whites. These patterns have prompted suggestions to lower the screening age for average-risk populations or in blacks. At the same time, there has been controversy over whether reductions in CRC incidence can be attributed to screening...
September 5, 2016: Clinical Gastroenterology and Hepatology
Peter S Liang, Jonathan D Mayer, Jon Wakefield, Cynthia W Ko
PURPOSE: Colorectal cancer (CRC) incidence and mortality in the United States have steadily declined since the 1980s, but racial and socioeconomic disparities remain. The influence of geographic factors is poorly understood and may be affected by evolving insurance coverage and screening test uptake. We characterized temporal trends in the association between geographic and sociodemographic factors and CRC outcomes. METHODS: We used the 1973-2010 SEER-Medicare files to identify patients aged ≥65 years with and without CRC...
August 31, 2016: Journal of Rural Health
Zhen-Yu Zhang, Qi-Feng Luo, Xiao-Wei Yin, Zhen-Ling Dai, Shiva Basnet, Hai-Yan Ge
BACKGROUND: The predictive accuracy of the American Joint Committee on Cancer (AJCC) stages of colorectal cancer (CRC) is mediocre. This study aimed to develop postoperative nomograms to predict cancer-specific survival (CSS) and overall survival (OS) after CRC resection without preoperative therapy. METHODS: Eligible patients with stage I to IV CRC (n = 56072) diagnosed from 2004 to 2010 were selected from the Surveillance, Epidemiology, and End Results (SEER) database...
2016: BMC Cancer
Chun Chieh Lin, Katherine S Virgo, Anthony S Robbins, Ahmedin Jemal, Elizabeth M Ward
BACKGROUND: Physicians routinely factor comorbidities into diagnostic and treatment decisions. Analyses of treatment patterns and outcomes using the National Cancer Data Base (NCDB) usually adjust for comorbidities; however, the completeness of comorbidity ascertainment in the NCDB has never been assessed. We compared the prevalence of comorbidities captured in the NCDB and Surveillance, Epidemiology, and End Results (SEER)-Medicare among female breast, non-small-cell lung, and colorectal cancer patients aged ≥66...
August 17, 2016: Annals of Surgical Oncology
Stephanie L Jarosek, Tetyana P Shippee, Beth A Virnig
OBJECTIVES: To use place-of-service (POS) codes in the Medicare hospice claims files to document where elderly hospice users with cancer die. DESIGN: Retrospective cohort study. SETTING: Surveillance, Epidemiology, and End Results (SEER) cancer registry areas. PARTICIPANTS: Elderly Medicare beneficiaries who died of lung, breast, colorectal, or pancreatic cancer in 2007 and 2008 (N = 46,037). MEASUREMENT: Use of hospice, place of service at death (home, nursing home, hospital, inpatient hospice, other), length of stay in hospice...
September 2016: Journal of the American Geriatrics Society
Jessica L Krok-Schoen, James L Fisher, Ryan D Baltic, Electra D Paskett
BACKGROUND: Increased life expectancy, growth of minority populations, and advances in cancer screening and treatment have resulted in an increasing number of older, racially diverse cancer survivors. Potential black/white disparities in cancer incidence, stage, and survival among the oldest old (≥85 years) were examined using data from the SEER Program of the National Cancer Institute. METHODS: Differences in cancer incidence and stage at diagnosis were examined for cases diagnosed within the most recent 5-year period, and changes in these differences over time were examined for white and black cases aged ≥85 years...
August 15, 2016: Cancer Epidemiology, Biomarkers & Prevention
C Mosquera, N J Koutlas, T L Fitzgerald
BACKGROUND: Due to the limited sample size in the existing series, the natural history and management of high-grade gastroenteropancreatic neuroendocrine tumors (GEP-NET) is poorly understood. In order to better understand high-grade GEP-NET, a large cohort study was undertaken. OBJECTIVE: To determine the prognostic factors associated with high-grade GEP-NET. METHODS: Patients diagnosed with non-metastatic high-grade GEP-NET from 1988 to 2010 were identified in SEER...
October 2016: European Journal of Surgical Oncology
Tzy-Mey Kuo, Lee R Mobley
BACKGROUND: We determined whether the current SEER registries are representative of the nation's cancer cases or the socio-demographic characteristics. METHODS: We used breast cancer (BC) and colorectal cancer (CRC) cases diagnosed 2004-2009 from the US Cancer Statistics (USCS) database. Cases were classified into groups residing in SEER coverage areas and the other areas. We compared difference between SEER and non-SEER areas in: age-race-specific proportions of late-stage BC or CRC, area demographics and socioeconomic factors, and data quality...
September 2016: Cancer Causes & Control: CCC
Pallavi B Rane, S Suresh Madhavan, Usha Sambamoorthi, Kalidindi Sita, Sobha Kurian, Xiaoyun Pan
The aim was to examine and compare with "national" estimates, receipt of colorectal cancer (CRC) treatment in the initial phase of care and survival following a CRC diagnosis in rural Medicare beneficiaries. A retrospective study was conducted on fee-for-service Medicare beneficiaries diagnosed with CRC in 2003-2006, identified from West Virginia Cancer Registry (WVCR)-Medicare linked database (N = 2119). A comparative cohort was identified from Surveillance, Epidemiology, and End Results (SEER)-Medicare (N = 38,168)...
July 15, 2016: Population Health Management
Ioana Popescu, Deborah Schrag, Alfonso Ang, Mitchell Wong
BACKGROUND: Despite a large body of research showing racial/ethnic and socioeconomic disparities in cancer treatment quality, the relative role of physician-level variations in care is unclear. OBJECTIVE: To examine the effect of physicians on disparities in breast and colorectal cancer care. SUBJECTS: Linked SEER Medicare data were used to identify Medicare beneficiaries diagnosed with colorectal and breast cancer during 1995-2007 and their treating physicians...
August 2016: Medical Care
Myles J Smith, Henry G Smith, Alyson L Mahar, Calvin Law, Yoo-Joung Ko
A higher incidence of additional malignancies has been described in patients diagnosed with gastrointestinal stromal tumors (GIST). This study aimed to identify risk factors for developing additional malignancies in patients diagnosed with GIST and evaluate the impact on survival. Individuals diagnosed with GIST from 2001 to2009 were identified from the SEER database. Logistic regression was used to identify predictors of additional malignancies and Cox-proportional hazards regression used to identify predictors of survival...
October 15, 2016: International Journal of Cancer. Journal International du Cancer
Erica R H Sutton, Samuel Walling, Charles Kimbrough, Nikhil Borkhetaria, Whitney Jones, Brad Sutton
BACKGROUND: Uninsured patients have poor access to screening colonoscopy and subsequently present with advanced stages of colorectal cancer (CRC) that beget worse outcomes and higher total costs. Providing pro bono colonoscopies to uninsured patients at high risk for CRC can detect early stage disease and be cost-effective. STUDY DESIGN: Patients considered at increased risk for CRC were offered free screening colonoscopies. Patient data from these colonoscopies were collected during a 12-month period, and the incidence of CRC was compared with a control group of uninsured patients from the Surveillance, Epidemiology, and End Results (SEER) registry...
July 2016: Journal of the American College of Surgeons
Shaheenah Dawood, Bhawna Sirohi, Shailesh V Shrikhande, Han-Chong Toh, Cathy Eng
Prognostic role of surgical resection of the primary tumor and baseline CEA among patients with synchronous stage IV colorectal cancer (CRC) remains an area of debate. The objective of this study was to determine the prognostic value of baseline CEA and surgical resection of the primary among patients with synchronous stage IV CRC in the era of modern chemotherapy and biologic therapy. The Surveillance, Epidemiology and End Results Registry was searched to identify patients with synchronous stage IV CRC diagnosed between 2004 and 2009...
September 2015: Indian Journal of Surgical Oncology
John Bian, Charles Bennett, Gregory Cooper, Alessandra D'Alfonso, Deborah Fisher, Joseph Lipscomb, Chao-Nan Qian
INTRODUCTION: There are concerns about potential overuse of colorectal cancer (CRC) screening services among average-risk individuals older than age 75 years. MATERIALS AND METHODS: Using a 5% random noncancer sample of Medicare beneficiaries who resided in the SEER areas, we examined rates of CRC screening adherence, defined by the Medicare coverage policy, among average-risk fee-for-service beneficiaries age 76 to 95 years from 2002 to 2010. The two outcomes are the status of overall CRC screening adherence, and the status of adherence to colonoscopy (v other modalities) conditional on patient adherence...
June 2016: Journal of Oncology Practice
Kevin D Frick, Claire F Snyder, Robert J Herbert, Amanda L Blackford, Bridget A Neville, Antonio C Wolff, Michael A Carducci, Craig C Earle
PURPOSE: To estimate the association between cancer survivors' comorbid condition care quality and costs; to determine whether the association differs between cancer survivors and other patients. METHODS: Using the SEER-Medicare-linked database, we identified survivors of breast, prostate, and colorectal cancers who were diagnosed in 2004, enrolled in Medicare fee-for-service for at least 12 months before diagnosis, and survived ≥ 3 years. Quality of care was assessed using nine process indicators for chronic conditions, and a composite indicator representing seven avoidable outcomes...
June 2016: Journal of Oncology Practice
Clancy J Clark, Nora F Fino, Jia Hao Liang, David Hiller, Jaime Bohl
PURPOSE: Colorectal cancer survivorship has improved significantly over the last 20 years; however, few studies have evaluated depression among older colorectal cancer survivors, especially using a population-based sample. The aim of this study was to identify correlates for positive depression screen among colorectal cancer survivors who underwent potentially curative surgery. METHODS: Using the 1998-2007 Surveillance, Epidemiology, and End-Result registry and the Medicare Health Outcome Survey linked dataset, we identified patients over 65 with pathology confirmed and resected colorectal cancer enrolled in Medicare...
September 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
A Amini, B L Jones, N Yeh, S R Guntupalli, B D Kavanagh, S D Karam, C M Fisher
OBJECTIVES: Current guidelines support the use of screening for early detection in breast, prostate, colorectal and cervical cancer. The purpose of this study was to evaluate whether insurance status predicts for more advanced disease in these four currently screened cancers. STUDY DESIGN: The Surveillance, Epidemiology, and End Results (SEER) database was queried for breast, prostate, colorectal and cervix in patients aged 18-64 years. The database was queried from 2007 to 2011, with 425,614 patients with known insurance status included...
September 2016: Public Health
Eric J Roeland, Daniel P Triplett, Rayna K Matsuno, Isabel J Boero, Lindsay Hwang, Heidi N Yeung, Loren Mell, James D Murphy
BACKGROUND: The role of palliative care has expanded over the past several decades, although the oncology-specific regional evolution of this specialty has not been characterized at the population-based level. METHODS: This study defined the patterns of palliative care delivery using a retrospective cohort of patients with advanced cancer within the SEER-Medicare linked database. We identified 83,022 patients with metastatic breast, prostate, lung, and colorectal cancers...
April 2016: Journal of the National Comprehensive Cancer Network: JNCCN
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