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https://www.readbyqxmd.com/read/29139055/downstream-breast-imaging-following-screening-mammography-in-medicare-patients-with-advanced-cancer-a-population-based-study
#1
Gelareh Sadigh, Richard Duszak, Kevin C Ward, Renjian Jiang, Jeffrey M Switchenko, Kimberly E Applegate, Ruth C Carlos
BACKGROUND: Screening tests are generally not recommended in patients with advanced cancer and limited life expectancy. Nonetheless, screening mammography still occurs and may lead to follow-up testing. OBJECTIVE: We assessed the frequency of downstream breast imaging following screening mammography in patients with advanced colorectal or lung cancer. DESIGN: Population-based study. PARTICIPANTS: The study included continuously enrolled female fee-for-service Medicare beneficiaries ≥65 years of age with advanced colorectal (stage IV) or lung (stage IIIB-IV) cancer reported to a Surveillance, Epidemiology, and End Results (SEER) registry between 2000 and 2011...
November 14, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29118227/nonadherence-to-statins-and-antihypertensives-and-hospitalizations-among-elderly-medicare-beneficiaries-with-incident-cancer
#2
Ishveen Chopra, Nilanjana Dwibedi, Malcolm D Mattes, Xi Tan, Patricia Findley, Usha Sambamoorthi
Background: Incident cancer diagnosis may increase the risk of coronary artery disease (CAD)-related hospitalizations, especially in older individuals. Adherence to statins and/or angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin II receptor blockers (ARBs)/β-blockers reduces CAD-related hospitalizations. This study examined the relationship between medication adherence and CAD-related hospitalizations immediately following cancer diagnosis. Patients and Methods: A retrospective observational longitudinal study was conducted using SEER-Medicare data...
November 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29108382/clinicopathologic-features-and-prognostic-factors-for-patients-with-colorectal-cancer-who-are-75-years-and-older
#3
Mingfang Zhao, Hans Liu, Yanqing Tang, Xin Meng, Jun Yu, Qi Wang, Qiao Zhou, Sean X Leng, Haiyan Zhang
Colorectal cancer (CRC) is common and can be considered as a disease of older adults. About one half of the cases were diagnosed in patients over 70 years of age. Decision-making about treatment for these older patients can be complicated by age-related physiological changes, impaired functional status, limited social support, and comorbidities. Many trials excluded patients using an upper limit of 75 years of age. Little is known about prognostic factors in patients who are over this age limit. In this study, we conducted an analysis in the Surveillance, Epidemiology and End Results (SEER) database to identify specific clinicopathologic features and prognostic factors for these vulnerable cancer patients (N= 293,616)...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28971494/direct-likelihood-inference-on-the-cause-specific-cumulative-incidence-function-a-flexible-parametric-regression-modelling-approach
#4
Sarwar Islam Mozumder, Mark Rutherford, Paul Lambert
In a competing risks analysis, interest lies in the cause-specific cumulative incidence function (CIF) that can be calculated by either (1) transforming on the cause-specific hazard or (2) through its direct relationship with the subdistribution hazard. We expand on current competing risks methodology from within the flexible parametric survival modelling framework (FPM) and focus on approach (2). This models all cause-specific CIFs simultaneously and is more useful when we look to questions on prognosis. We also extend cure models using a similar approach described by Andersson et al for flexible parametric relative survival models...
October 2, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28882404/health-related-quality-of-life-following-radical-cystectomy-comparative-analysis-from-the-medicare-health-outcomes-study
#5
Brian R Winters, Jonathan L Wright, Sarah K Holt, Atreya Dash, John L Gore, George R Schade
PURPOSE: Health related quality of life (HRQOL) after radical cystectomy (RC) and ileal conduit is not well quantified at the population level. We evaluated HRQOL in patients with bladder cancer (BC) compared with non-cancer controls (NCC) and colorectal cancer (CRC) patients using SEER-Medicare Health Outcomes Survey (MHOS) data. MATERIALS AND METHODS: SEER-MHOS data (1998-2013) was used to identify patients with BC and CRC undergoing extirpative surgery with ileal conduit or colostomy creation...
September 4, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28866818/examining-colorectal-cancer-survivors-surveillance-patterns-and-experiences-of-care-a-seer-cahps-study
#6
Michelle A Mollica, Lindsey R Enewold, Lisa M Lines, Michael T Halpern, Jessica R Schumacher, Ron D Hays, James T Gibson, Nicola Schussler, Erin E Kent
PURPOSE: We examined associations between experiences of care and adherence to surveillance guidelines among Medicare Fee-For-Service beneficiaries with colorectal cancer (CRC). METHODS: Using linked data from the National Cancer Institute's Surveillance, Epidemiology, and End results (SEER) cancer registry program and the Medicare Consumer Assessment of Healthcare Providers and Systems (CAHPS(®)) patient experience surveys (SEER-CAHPS), we identified local/regional CRC survivors diagnosed in 1999-2009 aged 65+, who underwent surgical resection and completed a CAHPS survey <36 months of diagnosis...
October 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28822996/examining-bias-in-studies-of-statin-treatment-and-survival-in-patients-with-cancer
#7
Louise Emilsson, Xabier García-Albéniz, Roger W Logan, Ellen C Caniglia, Mette Kalager, Miguel A Hernán
Importance: Patients with cancer who use statins appear to have a substantially better survival than nonusers in observational studies. However, this inverse association between statin use and mortality may be due to selection bias and immortal-time bias. Objective: To emulate a randomized trial of statin therapy initiation that is free of selection bias and immortal-time bias. Design, Setting, and Participants: We used observational data on 17 372 patients with cancer from the Surveillance, Epidemiology, and End Results (SEER)-Medicare database (2007-2009) with complete follow-up until 2011...
August 20, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28735257/prognostic-factors-of-overall-survival-and-cancer-specific-survival-in-patients-with-resected-early-stage-rectal-adenocarcinoma-a-seer-based-study
#8
Ko-Chao Lee, Kuan-Chih Chung, Hong-Hwa Chen, Chia-Cheng Liu, Chien-Chang Lu
The benefits of radiotherapy for colorectal cancer are well documented, but the impact of adjuvant radiotherapy on early-stage rectal adenocarcinoma remains unclear. This study aimed to identify predictors of overall survival (OS) and cancer-specific survival (CSS) in patients with stage II rectal adenocarcinoma treated with preoperative or postoperative radiation therapy. Patients with early-stage rectal adenocarcinoma in the postoperative state were identified using the Surveillance, Epidemiology, and End Results database...
July 21, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28732371/the-impacts-of-surgery-of-the-primary-cancer-and-radiotherapy-on-the-survival-of-patients-with-metastatic-rectal-cancer
#9
Duo Tong, Fei Liu, Wenhua Li, Wen Zhang
The role of surgery of the primary cancer and radiation in metastatic colorectal cancer (mCRC) is still controversial currently, and evidence implied that colon cancer (CC) and rectal cancer (RC) should be treated with difference. Hence we focused on metastatic rectal cancer (mRC) solely to compare the cancer cause-specific survival (CSS) of patients receiving varied treatments of the primary cancer: no treatment, surgery only, radiation only, and surgery plus radiation, based on the records of the Surveillance, Epidemiology, and End Results (SEER) database...
July 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28618843/risk-of-cardiac-death-among-cancer-survivors-in-the-united-states-a-seer-database-analysis
#10
Omar Abdel-Rahman
BACKGROUND: Population-based data on the risk of cardiac death among cancer survivors are needed. This scenario was evaluated in cancer survivors (>5 years) registered within the Surveillance, Epidemiology and End Results (SEER) database. METHODS: The SEER database was queried using SEER*Stat to determine the frequency of cardiac death compared to other causes of death; and to determine heart disease-specific and cancer-specific survival rates in survivors of each of the 10 most common cancers in men and women in the SEER database...
September 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28441110/effects-of-the-us-food-and-drug-administration-boxed-warning-of-erythropoietin-stimulating-agents-on-utilization-and-adverse-outcome
#11
John Bian, Brian Chen, Dawn L Hershman, Norman Marks, LeAnn Norris, Richard Schulz, Charles L Bennett
Purpose In March 2007, a US Food and Drug Administration boxed warning was issued for erythropoietin-stimulating agents (ESAs) regarding serious adverse events, such as venous thromboembolism (VTE). We evaluated the US Food and Drug Administration's boxed warning of ESAs used to treat chemotherapy-induced anemia because evidence on the effectiveness of boxed warnings remains inconclusive. Patients and Methods Using 2004 to 2009 SEER-Medicare data, we exploited a natural experiment to examine the effects of ESA boxed warnings on utilization and risk of VTE...
June 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28437692/stage-iv-colorectal-cancer-primary-site-and-patterns-of-distant-metastasis
#12
Jamaica R Robinson, Polly A Newcomb, Sheetal Hardikar, Stacey A Cohen, Amanda I Phipps
BACKGROUND: Although colorectal cancer (CRC) usually metastasizes to the liver and/or lungs, factors influencing the anatomic pattern of metastases remain poorly understood. METHODS: We assessed the relationship between primary CRC site and pattern of synchronous metastasis among 1202 individuals diagnosed with incident metastatic CRC between 2010 and 2014 and identified through the Seattle-Puget Sound Surveillance, Epidemiology, and End Results (SEER) registry...
June 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28430643/lymph-node-status-as-a-prognostic-factor-after-palliative-resection-of-primary-tumor-for-patients-with-metastatic-colorectal-cancer
#13
Qingguo Li, Changjian Wang, Yaqi Li, Xinxiang Li, Ye Xu, Guoxiang Cai, Peng Lian, Sanjun Cai
Lymph node (LN) status is one of the most important predictors for M0 colorectal cancer patients. However, its clinical impact on stage IV colorectal cancer remains unclear. The study aimed to explore the prognostic value of LN status after palliative resection of primary tumor for patients with metastatic colorectal cancer (mCRC). We combined analyses of mCRC patients in Surveillance, Epidemiology and End Results (SEER) database and Fudan University Shanghai Cancer Center (FUSCC).A total of 17,553 patients with mCRC were identified in SEER database...
July 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28426915/improvements-in-colorectal-cancer-incidence-not-experienced-by-nonmetropolitan-women-a-population-based-study-from-utah
#14
Brynn Fowler, N Jewel Samadder, Deanna Kepka, Qian Ding, Lisa Pappas, Anne C Kirchhoff
PURPOSE: Little is known about disparities in colorectal cancer (CRC) incidence and mortality by community-level factors such as metropolitan status. METHODS: This analysis utilized data from the Surveillance, Epidemiology, and End Results (SEER) program from Utah. We included patients diagnosed with CRC from 1991 to 2010. To determine whether associations existed between metropolitan/nonmetropolitan county of residence and CRC incidence, Poisson regression models were used...
April 20, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28426375/united-states-population-based-estimates-of-patient-reported-outcomes-measurement-information-system-symptom-and-functional-status-reference-values-for-individuals-with-cancer
#15
Roxanne E Jensen, Arnold L Potosky, Carol M Moinpour, Tania Lobo, David Cella, Elizabeth A Hahn, David Thissen, Ashley Wilder Smith, Jaeil Ahn, George Luta, Bryce B Reeve
Purpose To estimate cancer population-based reference values in the United States for eight PROMIS (Patient-Reported Outcomes Measurement Information System) domains by age and stage of disease. Patients and Methods For the Measuring Your Health (MY-Health) study, persons newly diagnosed with cancer (prostate, colorectal, non-small-cell lung, non-Hodgkin lymphoma, breast, uterine, or cervical) from 2010 to 2012 (N = 5,284) were recruited through the National Cancer Institute's SEER Program. Participants were mailed surveys 6 to 13 months after diagnosis...
June 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28407201/cancer-incidence-profile-in-sub-saharan-african-born-blacks-in-the-united-states-similarities-and-differences-with-us-born-non-hispanic-blacks
#16
Genet A Medhanie, Stacey A Fedewa, Hibret Adissu, Carol E DeSantis, Rebecca L Siegel, Ahmedin Jemal
BACKGROUND: Sub-Saharan African-born blacks (ABs) are one of the fastest-growing populations in the United States. However, to the authors' knowledge, data regarding the cancer burden in this group are lacking, which would inform targeted cancer prevention and control. METHODS: The authors calculated age-standardized proportional incidence ratios (PIRs) comparing the frequency of the top 15 cancers in ABs with that of US-born non-Hispanic blacks (USBs) by sex and region of birth using incidence data for 2000 through 2012 from the Surveillance, Epidemiology, and End Results (SEER 17) program...
August 15, 2017: Cancer
https://www.readbyqxmd.com/read/28388972/disparities-in-incidence-of-early-and-late-onset-colorectal-cancer-between-hispanics-and-whites-a-10-year-seer-database-study
#17
Jenna Koblinski, Jana Jandova, Valentine Nfonsam
BACKGROUND: Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012. METHODS: We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases. RESULTS: The overall incidence of CRC increased by 48% in Hispanics...
March 31, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28345614/prognosis-and-value-of-preoperative-radiotherapy-in-locally-advanced-rectal-signet-ring-cell-carcinoma
#18
Chun-Run Ling, Rui Wang, Mo-Jin Wang, Jie Ping, Wen Zhuang
As well known, signet-ring cell carcinoma (SRCC) is a rare histological subtype of colorectal adenocarcinoma, which has been associated with poor prognosis and resistant to non-surgery therapy compared with common adenocarcinoma. In this study, we assessed the effect of preoperative radiotherapy (PRT) for locally advanced rectal SRCC in a large patient group from the Surveillance, Epidemiology, and End Results program (SEER, 1988-2011) database. SRCC was found in 0.9% (n = 622) rectal cancer (RC) patients in our study...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28325489/breast-cancer-screening-in-patients-with-newly%C3%A2-diagnosed-lung-and-colorectal-cancer-%C3%A2-a%C3%A2-population-based-study-of-utilization
#19
Gelareh Sadigh, Ruth C Carlos, Kevin C Ward, Jeffrey M Switchenko, Renjian Jiang, Kimberly E Applegate, Richard Duszak
PURPOSE: To assess breast cancer screening utilization in Medicare beneficiaries with colorectal and lung cancer versus cancer-free controls. METHODS: Female fee-for-service Medicare beneficiaries who were ≥67 years old and diagnosed with lung or colorectal cancer between 2000 and 2011 and who reported to a Surveillance, Epidemiology, and End Results (SEER) registry (case group) were followed for 2 years after their diagnoses, unless death, a diagnosis of breast cancer, or the end of 2013 came first...
July 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28314541/risk-of-subsequent-primary-kidney-cancer-after-another-malignancy-a-population-based-study
#20
Omar Abdel-Rahman
BACKGROUND: Population-based data on the development of kidney cancer as a second malignant neoplasm following the diagnosis of other common malignancies are rare. This clinical scenario has been evaluated within the Surveillance, Epidemiology, and End Results (SEER) database. MATERIALS AND METHODS: The SEER-9 database (1973-2013) was queried using the SEER*Stat program to determine the standardized incidence ratios (SIRs) of kidney cancer development following each one of 10 common invasive malignancies (colorectal, breast, prostate, lung, thyroid, corpus uteri, urinary bladder, kidney/renal pelvis, cutaneous melanoma, and non-Hodgkin lymphoma)...
February 27, 2017: Clinical Genitourinary Cancer
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