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Solitary plasmacytoma

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https://www.readbyqxmd.com/read/28797508/hematopoietic-tumors-primarily-presenting-in-bone
#1
REVIEW
Arjen H G Cleven, Pancras C W Hogendoorn
Hematologic neoplasms that primarily present in bone are rare; this article describes the most common examples of hematologic tumors primarily presenting in bone, including plasma cell myeloma, solitary plasmacytoma of bone, primary non-Hodgkin lymphoma of bone, acute lymphoblastic leukemia/lymphoma, and Langerhans cell histiocytosis. The macroscopic and microscopic features, differential diagnosis, diagnostic workup, and prognosis of all these different entities are discussed, with special emphasis on common differential diagnosis...
September 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28795553/-chronic-demyelinating-polyradiculoneuropathy-revealing-a-solitary-plasmacytoma-of-the-right-iliac-bone
#2
J Oumerzouk, A Bourazza
Solitary bone plasmacytoma (pso) is a rare tumor, made of malignant plasma cells observed in a single bone, and without systemic proliferation. We report the case of a 33 year-old man who was admitted with chronic demyelinating sensorimotor polyneuropathy. Immunoelectrophoresis with immunofixation of serum proteins showed a monoclonal peak igg with lambda light chain and the workup was in favour of right hipbone secreting solitary plasmacytoma. The patient was treated with radiotherapy and steroids, and the evolution has been marked by a partial recovery of the motor deficit...
July 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28793931/strategy-for-the-treatment-and-follow-up-of-sinonasal-solitary-extramedullary-plasmacytoma-a-case-series
#3
Elena Cantone, Antonella Miriam Di Lullo, Luana Marano, Elia Guadagno, Gelsomina Mansueto, Pasquale Capriglione, Lucio Catalano, Maurizio Iengo
BACKGROUND: Extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells outside bone marrow. It accounts for 4% of all non-epithelial sinonasal tumors. According to the literature, radiotherapy is the standard therapy for extramedullary plasmacytoma. However, the conversion rate of extramedullary plasmacytoma to multiple myeloma is reported to be between 11 and 33% over 10 years. The highest risk of conversion is reported during the first 2 years after diagnosis, but conversion has been noted up to 15 years after diagnosis...
August 10, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28761547/plasmacytoma-of-the-clivus
#4
R Amita, S Sandhyamani, Suresh Nair, T R Kapilamoorthy
We report a case of solitary plasmacytoma of the clivus in a 55 year old male.
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28758008/bilateral-extramedullary-adrenal-plasmacytoma-case-report-and-review-of-the-literature
#5
REVIEW
Philip J Townend, Gabriel Kraus, Luke Coyle, David Nevell, Anton Engelsman, Stan B Sidhu
Extramedullary plasmacytoma (EMP) accounts for only 3% of plasma cell malignancies; others include multiple myeloma, plasma cell leukemia and solitary plasmacytoma of bone. The majority of EMPs are found in the upper respiratory tract. Other sites include the GI tract, bladder, CNS, thyroid, breast, testes, parotid gland, lymph nodes and skin. There are eight cases in the literature of adrenal plasmacytoma, however, only two were bilateral. We describe our recent experience of bilateral adrenal plasmacytoma and review of the literature...
May 2017: International Journal of Endocrine Oncology
https://www.readbyqxmd.com/read/28716071/primary-solitary-plasmacytoma-of-the-liver-successful-treatment-with-fractionated-stereotactic-radiotherapy-cyberknife%C3%A2-a-case-report
#6
Thomas Chalopin, Isabelle Barillot, Jean-Paul Biny, Flavie Arbion, Marie Besson, Maria Santiago-Ribeiro, Eric Piver, Olivier Herault, Emmanuel Gyan, Lotfi Benboubker
BACKGROUND: Solitary plasmacytoma of the liver is a very rare and aggressive form of plasma cell dyscrasia. To the best of our knowledge, very few cases have been reported without systemic disease. We reported a rare case of hepatic solitary plasmacytoma that successfully responded to fractionated stereotactic radiotherapy. CASE PRESENTATION: A 64-year-old white French man had monoclonal gammopathy of the immune globulin G lambda type; he developed a cholestasis and cytolysis with the discovery of a subscapular nodule...
July 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28645258/erratum-to-solitary-plasmacytoma-population-based-analysis-of-survival-trends-and-effect-of-various-treatment-modalities-in-the-usa
#7
Nishitha Thumallapally, Ahmed Meshref, Mohammed Mousa, Terenig Terjanian
No abstract text is available yet for this article.
June 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28640138/an-unusual-presentation-of-multiple-myeloma-with-unilateral-sudden-vision-loss-a-case-report
#8
Pei-Wen Wu, Ta-Jen Lee, Jim-Ray Chen, Chien-Chia Huang
RATIONALE: Plasma cell neoplasms are categorized by neoplastic proliferation of a single clone of plasma cells which produce a monoclonal immunoglobulin. Plasma cell neoplasms can present as a solitary plasmacytoma or as multiple myeloma. Both of them can progress to multiple myeloma. Once a diagnosis of plasmacytoma has been made, thorough examinations should be carried out for identifying the disease entity. PATIENT CONCERNS AND DIAGNOSES: Herein, we describe an extraordinary rare case of multiple myeloma with initial presentation of a left sphenoid neoplasm resulting in left-sided headache and rapid deterioration of visual acuity...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28620568/bilateral-myelomatous-pleural-effusion-in-a-patient-with-iga-kappa-multiple-myeloma
#9
Rebecca Asiamah, Shiva Kumar Mukkamalla, Tanmay Sahai, Xiao Ping Zhou, Eric Han, Vincent Armenio
Multiple myelomas is a neoplastic plasma cell disorder that accounts for one percent of all cancers and 13% of hematologic malignancies. Although primarily known to be a bone marrow disorder, it can metastasize to extramedullary sites or it can present as a solitary extramedullary plasmacytoma. Primary pleural effusion from myeloma is rare, occurring in less than one percent of the patients. The following case report highlights a case of bilateral pleural effusion, directly attributable to multiple myeloma after other causes were ruled out...
May 10, 2017: Curēus
https://www.readbyqxmd.com/read/28594699/solitary-iris-plasmacytoma-with-anterior-chamber-crystalline-deposits
#10
Andrew W Stacey, Alenka Lavric, Caroline Thaung, Samreen Siddiq, Mandeep S Sagoo
PURPOSE: To report a case of solitary iris plasmacytoma successfully treated with ruthenium plaque radiotherapy. METHODS: A 44-year-old white woman presented with pain in the right eye and raised intraocular pressure. Her medical history included breast cancer treated 11 years earlier with lumpectomy, lymph node clearance, chemotherapy, and radiotherapy. On examination, the right iris had a tan-colored mass with crystalline deposits visible on the mass surface and on the corneal endothelium...
July 2017: Cornea
https://www.readbyqxmd.com/read/28586406/a-solitary-cardiac-plasmacytoma-features-in-multimodality-imaging
#11
Jong-Ho Nam, Chi Young Shim, Darae Kim, Seung-Hyun Lee, Geu-Ru Hong
No abstract text is available yet for this article.
June 5, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28584670/solitary-plasmacytoma-of-the-mesentery-a-systematic-clinician-s-diagnosis
#12
Georgia Mitropoulou, Adamantia Zizi-Sermpetzoglou, Hippokrates Moschouris, Athanasios Kountourogiannis, Despoina Myoteri, Dionysios Dellaportas
INTRODUCTION: Plasmacytoma is an uncommon plasma cell neoplasm and its localized form is solitary plasmacytoma of the bone and solitary extramedullary plasmacytoma. Solitary plasmacytoma of the mesentery is extremely rare, reported only in a handful of cases. CASE PRESENTATION: A 47-year-old man with nonspecific abdominal complains was found to have an ill-defined mass on his mesenteric root. Laparoscopic biopsy and stepwise histopathological examination revealed a mesenteric plasmacytoma, and extensive imaging and laboratory investigations led to the diagnosis of the solitary mesenteric plasmacytoma...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28571247/extramedullary-solitary-plasmacytoma-demonstrating-the-role-of-18-f-fdg-pet-imaging
#13
Archana Gautam, Kamal Kant Sahu, Ahsan Alamgir, Imran Siddiqi, Sikander Ailawadhi
An Extramedullary Plasmacytoma (EMP) is characterized by a neoplastic proliferation of clonal plasma cells outside the medullary cavity. EMPs are a rare occurrence compared to other malignant plasma cell disorders and account for approximately 3-5% of plasma-cell neoplasms. Although most cases of EMP are not immediately life threatening at diagnosis, EMPs can progress to Multiple Myeloma (MM) and thus, warrant monitoring. Currently, there are no standard guidelines for when and how to monitor patients who are diagnosed with or treated for a solitary plasmacytoma...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28553386/solitary-plasmacytoma-of-bone-involving-spine-in-a-12-year-old-boy-report-of-a-rare-case-and-review-of-literature
#14
Rahul S Kulkarni, Sonia K Parikh, Asha S Anand, Harsha P Panchal, Apurva A Patel, Priti Trivedi, Kshitij Joshi, Pushpak Chirmade
Solitary plasmacytoma of the bone (SPB) is a rare plasma cell neoplasm representing only about 5% of plasma cell neoplasia. It usually presents as a lytic lesion mainly localized within the axial skeleton. SPB is exceedingly rare in young individuals, and only few cases have been reported so far in patients younger than 20 years of age. In view of rarity of disease, definitive treatment guidelines have not been established. We hereby report a case of SPB involving of lumbar vertebra (L5) in a 12-year-old boy...
January 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28544116/incidence-characteristics-and-outcome-of-solitary-plasmacytoma-and-plasma-cell-leukemia-population-based-data-from-the-swedish-myeloma-register
#15
Hareth Nahi, Anna Genell, Göran Wålinder, Katarina Uttervall, Gunnar Juliusson, Karin Forsberg, Markus Hansson, Ronald Svensson, Olle Linder, Kristina Carlson, Bo Björkstrand, Sigurdur Y Kristinsson, Ulf Henrik Mellqvist, Cecilie Blimark, Ingemar Turesson
Solitary plasmacytoma (SP) and Plasma cell leukemia (PCL) are uncommon (3-6%) types of plasma cell disease. The risk of progression to symptomatic multiple myeloma (MM) is probably important for the outcome of SP. PCL is rare and has a dismal outcome. In this study we report on incidence and survival in PCL/SP, and progression to MM in SP, using the prospective observational Swedish Multiple Myeloma Register designed to document all newly diagnosed plasma cell diseases in Sweden since 2008. Both solitary bone plasmacytoma (SBP), (n=124) and extramedullary plasmacytoma (EMP), (n=67) have better overall survival (OS) than MM (n=3549)...
May 22, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28465873/calvarial-plasmacytoma-mimicking-meningioma-as-the-initial-presentation-of-multiple-myeloma
#16
Peter Morgenstern, David Pisapia, Rohan Ramakrishna
Plasmacytoma of the calvarium is a well-described feature of multiple myeloma and in some cases has been reported as a solitary lesion. However, when associated with multiple myeloma these are typically identified after the initial diagnosis is made. This case is unusual in that the diagnosis of plasmacytoma was first suspected in a patient thought to have a meningioma on the day of surgery, when a magnetic resonance imaging (MRI) demonstrated spontaneous involution of the mass. Recognition of evolving changes in a calvarial or dural-based lesion should prompt the practitioner to consider alternative diagnoses other than meningioma prior to proceeding with surgical resection...
March 29, 2017: Curēus
https://www.readbyqxmd.com/read/28431708/extramedullary-plasmacytoma-arising-from-the-anterior-mediastinum
#17
Kiyoshi Sato, Satoshi Fumimoto, Takehisa Fukada, Yoshio Ichihashi, Kaoru Ochi, Hidetoshi Satomi, Takuya Morita, Nobuharu Hanaoka, Yoshikatsu Okada, Takahiro Katsumata
Plasmacytomas are a localized proliferation of plasma cells in the bone marrow and soft tissue. Extramedullary plasmacytomas are rare and typically solitary plasma cell neoplasms originating from extraosseous organs and tissues. A 31-year-old woman was referred to our hospital with a rapidly growing abnormal shadow on a chest roentgenogram. Chest computed tomography showed that the lesion was located in the anterior mediastinum. She underwent surgery, and the tumor was diagnosed as an extramedullary plasmacytoma...
May 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28413546/solitary-plasmacytoma-of-temporal-bone-a-rare-case-report
#18
Ritesh Kumar, Narendra Kumar, Sandeep Mohindro, B D Radotra
Solitary plasmacytoma of base of skull is a rare disease. It presents with headache, swelling, and other vague symptoms. Systemic work-up to rule out multiple myeloma is necessary. Radiotherapy is the treatment of choice. We, here, present a case of solitary plasmacytoma of base of skull in right temporal bone in a 50-year-old female treated with surgery and radiotherapy.
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28409043/rare-presentation-of-primary-extramedullary-plasmacytoma-as-lip-lesion
#19
Mali Him, Maggie Meier, Vikas Mehta
Malignant plasma cell proliferation can be presented as part of disseminated disease of multiple myeloma, as solitary plasmacytoma of bone, or in soft tissue as extramedullary plasmacytoma. Extramedullary plasmacytomas represented approximately 3% of all plasma cell proliferation. Approximately 80% of extramedullary plasmacytomas occur in the head and neck region while the other 4% occur in the skin and to a lesser extent in the lip. In this paper, we report a rare case of primary cutaneous plasmacytoma involving the lip in a 65-year-old male...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28393375/long-term-outcome-of-patients-with-solitary-plasmacytoma-treated-with-radiotherapy-a-population-based-single-center-study-with-median-follow-up-of-13-7%C3%A2-years
#20
Dlawer Abdulla Barzenje, Arne Kolstad, Waleed Ghanima, Harald Holte
In this single-center, population-based, and retrospective study, we analyzed the outcome of 49 patients with solitary bone plasmacytoma (SBP) and 28 patients with solitary extramedullary plasmacytoma (SEP), all treated with radiotherapy. Laminectomy was performed in 18/30 SBP patients with vertebral involvement and tumour resection in 10 SEP patients. Overall survival and cause of death for each patient were compared to 5 sex-, age-, and residency-matched individuals from the normal population. Response (complete and partial) was achieved in 94% of SBP and 96% of SEP patients...
April 9, 2017: Hematological Oncology
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