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Solitary plasmacytoma

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https://www.readbyqxmd.com/read/27829380/design-and-development-of-the-australian-and-new-zealand-anz-myeloma-and-related-diseases-registry
#1
Krystal Bergin, Elizabeth Moore, Zoe McQuilten, Erica Wood, Bradley Augustson, Hilary Blacklock, Joy Ho, Noemi Horvath, Tracy King, John McNeil, Peter Mollee, Hang Quach, Christopher M Reid, Brian Rosengarten, Patricia Walker, Andrew Spencer
BACKGROUND: Plasma cell dyscrasias (PCD) are a spectrum of disorders resulting from the clonal expansion of plasma cells, ranging from the pre-malignant condition monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM). MM generates a significant burden of disease on the community and it is predicted that it will increase in both incidence and prevalence owing to an ageing population and longer survival secondary to new therapeutic options. Robust and comprehensive clinical data are currently lacking but are required to define current diagnostic, investigational and management patterns in Australia and New Zealand (ANZ) for comparison to both local and international guidelines for standards of care...
November 9, 2016: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/27822103/the-danish-national-multiple-myeloma-registry
#2
REVIEW
Peter Gimsing, Morten O Holmström, Tobias Wirenfelt Klausen, Niels Frost Andersen, Henrik Gregersen, Robert Schou Pedersen, Torben Plesner, Per Trøllund Pedersen, Mikael Frederiksen, Ulf Frølund, Carsten Helleberg, Annette Vangsted, Peter de Nully Brown, Niels Abildgaard
AIM: The Danish National Multiple Myeloma Registry (DMMR) is a population-based clinical quality database established in January 2005. The primary aim of the database is to ensure that diagnosis and treatment of plasma cell dyscrasia are of uniform quality throughout the country. Another aim is to support research. Patients are registered with their unique Danish personal identification number, and the combined use of DMMR, other Danish National registries, and the Danish National Cancer Biobank offers a unique platform for population-based translational research...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27760483/management-of-gynaecologic-plasmacytoma-a-review-article
#3
Aharon M Feldman, Ziying Zhang, Thomas Buekers, Mohamed A Elshaikh
In contrast to multiple myeloma (MM) which exhibits diffuse bone marrow and other organ involvement, solitary plasmacytomas carry a favourable prognosis. Extramedullary plasmacytomas (EMP) are a unique form of plasma cell neoplasms. These tumours are rare in the female reproductive tract. Only 24 cases of gynaecologic plasmacytomas were reported to date (7 cases were solitary plasmacytomas and 17 cases were either part of disseminated MM with involvement of a gynaecologic organ or were lacking complete work-up to rule out MM)...
October 19, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27751979/an-incidental-solitary-plasmacytoma-of-bone-mimicking-neuroendocrine-tumor-metastasis-on-68ga-dotatate-positron-emission-tomography-computed-tomography
#4
Duygu Has Şimşek, Serkan Kuyumcu, Bilge Bilgiç, Emine Göknur Işık, Cüneyt Türkmen, Işık Adalet
A 54-year-old woman with suspicion of neuroendocrine tumor (NET) was referred for 68Ga-DOTATATE positron emission tomography/computed tomography (CT) imaging due to clinical findings. A well-defined osteolytic lesion on the corpus of the third lumbar vertebra was evident on CT images with mild uptake of 68Ga-DOTATATE, which led to suspicion of NET metastasis. Histopathologic examination revealed solitary plasmacytoma of the bone. The patient received local external radiotherapy for plasmacytoma. This case indicatesthat other diseases expressing somatostatin receptors may be inaccurately reported as tumor recurrence and highlights the importance of meticulous evaluation of positive findings...
October 5, 2016: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/27680220/successful-surgical-resection-of-solitary-plasmacytoma-of-the-liver-mimicking-hepatocellular-carcinoma-a-case-report
#5
Mariateresa Mirarchi, Emilio De Raffele, Francesco Bacci, Dajana Cuicchi, Ferdinando Lecce, Bruno Cola
: Solitary extramedullary plasmacitomas (SEMP) of the liver are very rare. We report the case of an elderly woman with a huge symptomatic SEMP of the liver mimicking hepatocellular carcinoma (HCC). The patient was a 89-year-old woman who presented with severe abdominal pain and a huge solid mass in the right hypochondrium. The laboratory data on admission revealed normal liver function tests. A multiphasic computed tomography (CT) showed a huge solid mass of the left hemiliver, hypoattenuating on noncontrast images, dishomogeneously hyperenhancing in the late arterial phase, with washout in the portal venous and equilibrium phases...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27675827/intensity-modulated-radiation-therapy-by-tomotherapy-imrt-concurrent-with-a-short-systemic-treatment-for-solitary-plasmacytoma-of-the-bone-spb-with-improvement-of-progression-free-survival
#6
E Le Ray, L Belin, C Plancher, D Bouscary, Y M Kirova
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27651943/solitary-plasmacytoma-of-the-mandible-an-uncommon-entity
#7
Ezher Hamza Dayisoylu, Ozcan Ceneli, Esra Zeypep Coskunoglu
INTRODUCTION: Plasma cell dyscrasias are characterized by a monoclonal neoplastic proliferation of plasma cells. Solitary bone plasmacytoma (SBP) is a local form of the disease with the vertebrae and long bones being the most frequently encountered sites. Its prevalence in the maxillofacial area is extremely rare. CASE PRESENTATION: A 70-year-old Caucasian male patient was referred for the extraction of his mobile premolar tooth with a poorly-defined radiolucent lesion...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27648261/solitary-extraosseous-plasmacytoma
#8
Hussein Merza, Raj Sarkar
Plasma cell neoplasms are characterized by a neoplastic plasma cell lineage which produces a monoclonal immunoglobulin. These neoplasms can present as a single lesion (solitary plasmacytoma) or as multiple lesions (multiple myeloma). Solitary plasmacytomas most frequently occur in bone (plasmacytomas of bone), but can also be found outside bone in soft tissues (extramedullary plasmacytomas).
September 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27611798/successful-treatment-of-primary-advanced-gastric-plasmacytoma-using-a-combination-of-surgical-resection-and-chemotherapy-with-bortezomib-a-case-report
#9
Sotaro Fukuhara, Hirofumi Tazawa, Hideharu Okanobu, Michiko Kida, Miki Kido, Toshiro Takafuta, Toshihiro Nishida, Hideki Ohdan, Hideto Sakimoto
INTRODUCTION: Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm that presents as a solitary tumor. EMP in the gastrointestinal organs are extremely uncommon. PRESENTATION OF CASE: A 36-year-old man was admitted to our hospital with advanced anemia. He had no specific medical history. Gastroendoscopic findings showed an 8.0-cm submucosal tumor with ulcer on the greater curvature of the gastric body. Fine-needle aspiration was performed, and the pathologic diagnosis of the submucosal tumor was a plasmacytoma...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27605358/progression-of-a-solitary-plasmacytoma-to-multiple-myeloma-a-population-based-registry-of-the-northern-netherlands
#10
Esther G M de Waal, Marnix Leene, Nic Veeger, Hanneke J Vos, Francisca Ong, Wilma G J M Smit, Sjoerd Hovenga, Mels Hoogendoorn, Marieke Hogenes, Max Beijert, Arjan Diepstra, Edo Vellenga
Plasmacytoma is characterized by a local accumulation of monoclonal plasma cells without criteria for multiple myeloma (MM). The current treatment regimen is local radiotherapy. However, more than 50% of patients develop MM within 2 years after treatment. A population-based registry was consulted for the diagnosis of solitary plasmacytoma between 1988 and 2011. Progression to MM and prognostic features for progression to MM were scored, including hypoxia inducible factors (HIF), vascular endothelial growth factor (VEGF, also termed VEGFA) and micro-vessel density (MVD) expression in biopsy material...
November 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27531229/giant-intracranial-solitary-plasmacytoma
#11
Osman Kara, Tayfur Toptaş, Işık Atagündüz, Süheyla Bozkurt, Önder Şirikçi, Tülin Fıratlı Tuğlular
No abstract text is available yet for this article.
August 16, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/27487779/primary-pulmonary-plasmacytoma-a-case-report-introduction
#12
Si Nie, De-Chang Peng, Hong-Han Gong, Cheng-Long Ye, Xiao Nie, Hai-Jun Li
BACKGROUND: Extramedullary plasmacytoma is a rare plasma cell neoplasm within soft tissue and without bone marrow involvement or other systemic characteristics of multiple myeloma. Primary pulmonary plasmacytoma is a rare type of extramedullary plasmacytoma. CASE PRESENTATION: A 48-year-old male with a tumor in the right middle ear was referred to our hospital. A routine chest X-ray was arranged and showed enlargement of the left lung hilum. His bilateral breathing sounded clear...
2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27467897/serum-free-light-chain-analysis-in-diagnosis-and-management-of-multiple-myeloma-and-related-conditions
#13
Paolo Milani, Giovanni Palladini, Giampaolo Merlini
The introduction of the serum-free light-chain (S-FLC) assay has been a breakthrough in the diagnosis and management of plasma cell dyscrasias, particularly monoclonal light-chain diseases. The first method, proposed in 2001, quantifies serum-free light-chains using polyclonal antibodies. More recently, assays based on monoclonal antibodies have entered into clinical practice. S-FLC measurement plays a central role in the screening for multiple myeloma and related conditions, in association with electrophoretic techniques...
2016: Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum
https://www.readbyqxmd.com/read/27408443/solitary-extramedullary-plasmacytoma-of-the-maxillary-sinus-progressing-to-smoldering-multiple-myeloma-with-multifocal-skeletal-involvement-which-resolved-completely-following-chemotherapy-alone
#14
Priya Jeyaraj, Manu Venkatesan, V S Nijhawan
Plasmacytoma is an uncommon malignant tumor originating either from plasma cells located in the bone marrow also known as the solitary bone plasmacytoma, or from plasma cells located outside the bone, for e.g. in mucosal surfaces, referred to as the extramedullary plasmacytoma also called the solitary extramedullary plasmacytoma. Both, solitary as well as extramedullary bone plasmacytomas may, particularly in later stages, be accompanied by other osteolytic bone lesions (multifocal bone involvement) and features such as anemia, hypercalcemia, or renal impairment attributable to and indicative of progression to multiple myeloma...
July 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27295445/solitary-plasmacytoma-of-the-petrous-apex-a-case-report-and-review-of-literature
#15
Tyler S Quist, Cheryl A Palmer, Joel D MacDonald, Richard K Gurgel
No abstract text is available yet for this article.
August 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27284562/extramedullary-plasmacytoma-of-the-oral-cavity-in-a-young-man-a-case-report
#16
Narges Gholizadeh, Masoumeh Mehdipour, Bita Rohani, Vahid Esmaeili
Extramedullary plasmacytomas are rare solitary soft tissue tumors that arise from proliferations of malignant transformed monoclonal plasma cells and can be diagnosed through biopsy and histopathologic examination. These lesions are closely associated with multiple myelomas, which should be ruled out in all these cases by necessary laboratory and radiographic examinations. A 25-year-old man was referred to our clinic with a rapidly-growing painless lesion measuring about 2.5×3×3 cm in the palatal side of the left maxillary second and third molar teeth...
June 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27284454/the-solitary-sellar-plasmacytoma-a-diagnostic-challenge
#17
Anne Soejbjerg, Suzan Dyve, Steen Baerentzen, Georg Thorsell, Per L Poulsen, Jens O L Jorgensen, Ulla Kampmann
UNLABELLED: Solitary sellar plasmacytomas are exceedingly rare and difficult to distinguish from other pituitary tumors. We report a case of a 62-year-old woman presenting with blurred vision of the right eye and tenderness of the right temporal region, which was interpreted as temporal arteritis. MRI revealed a pituitary mass lesion (20mm×14mm×17mm) without compression of the optic chiasm and her pituitary function was normal. Pituitary surgery was undertaken due to growth of the lesion, and histopathological examination showed a highly cellular neoplasm composed of mature monoclonal plasma cells...
2016: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/27249748/the-role-of-imaging-in-the-treatment-of-patients-with-multiple-myeloma-in-2016
#18
Evangelos Terpos, Meletios A Dimopoulos, Lia A Moulopoulos
The novel criteria for the diagnosis of symptomatic multiple myeloma have revealed the value of modern imaging for the management of patients with myeloma. Whole-body low-dose CT (LDCT) has increased sensitivity over conventional radiography for the detection of osteolytic lesions, and several myeloma organizations and institutions have suggested that whole-body LDCT should replace conventional radiography for the work-up of patients with myeloma. MRI is the best imaging method for the depiction of marrow infiltration by myeloma cells...
2016: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/27175345/collision-tumor-with-renal-cell-carcinoma-and-plasmacytoma-further-evidence-of-a-renal-cell-and-plasma-cell-neoplasm-relationship
#19
Sean W Berquist, Abd-Elrahman Said Hassan, Olga Miakicheva, Catherine Dufour, Zachary Hamilton, Ahmed Shabaik, Ithaar H Derweesh
Renal solitary extramedullary plasmacytomas belong to a group of plasma cell neoplasms, which generally have been associated with renal cell carcinoma. We present a case report of a patient with collision tumor histology of extramedullary plasmacytoma and clear cell renal cell carcinoma, the first in the known literature. Standard work-up for a plasma cell neoplasm was conducted and the mass was resected. The patient remains disease-free at 28 months post-surgery. The report calls into question pre-surgical renal mass biopsy protocol and suggests a relationship between renal cell carcinoma and plasma cell neoplasms...
May 2016: Urology Case Reports
https://www.readbyqxmd.com/read/27149599/right-lower-extremity-radiculopathy-from-a-solitary-plasmacytoma
#20
Johnathan Ho
No abstract text is available yet for this article.
May 4, 2016: American Journal of Physical Medicine & Rehabilitation
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