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intravenous anaesthesia

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https://www.readbyqxmd.com/read/28915921/total-intravenous-anaesthesia-in-a-goat-undergoing-craniectomy
#1
Verónica Vieitez, Ignacio Álvarez Gómez de Segura, Víctor López Rámis, Massimo Santella, Luis Javier Ezquerra
BACKGROUND: Cerebral coenurosis is a disease of the central nervous system in sheep and goats, and is usually fatal unless surgical relief is provided. Information regarding neuroanaesthesia in veterinary medicine in goats is scant. CASE PRESENTATION: We describe anaesthetic management of an intact female goat (2 years; 16 kg) presented for craniectomy. The goat was sedated with xylazine (0.05 mg kg(-1), i.m.) and morphine (0.05 mg kg(-1), i.m.). General anaesthesia was induced 20 min later with propofol and maintained with a constant rate infusion of propofol (0...
September 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28911282/what-are-we-injecting-with-our-drugs
#2
A F Merry, D A Gargiulo, L E Fry
In preparation for a case, an anaesthetist opened a 20 ml glass vial of propofol and aspirated the propofol into a syringe via a blunt drawing-up needle. Increased resistance was felt with aspiration. On inspection, a shard of glass was found at the tip of the drawing-up needle. The shard was presumed to be from the propofol ampoule, and to have fallen into the solution upon snapping open its glass tip. This illustrative case raises the issue of contamination of drugs by particles introduced during the drawing-up process...
September 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28894976/implicating-anaesthesia-and-the-perioperative-period-in-cancer-recurrence-and-metastasis
#3
Julia A Dubowitz, Erica K Sloan, Bernhard J Riedel
Cancer, currently the leading cause of death in the population aged less than 85 years, poses a significant global disease burden and is anticipated to continue to increase in incidence in both developed and developing nations. A substantial proportion of cancers are amenable to surgery, with more than 60% of patients undergoing tumour resection. Up to 80% of patients will receive anaesthesia for diagnostic, therapeutic or palliative intervention. Alarmingly, retrospective studies have implicated surgical stress in disease progression that is predominantly characterised by metastatic disease-the primary cause of cancer-associated mortality...
September 11, 2017: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/28891056/performance-of-the-minto-model-for-the-target-controlled-infusion-of-remifentanil-during-cardiopulmonary-bypass
#4
Y J Cho, W Y Jo, H Oh, C-H Koo, J Oh, J-Y Cho, K-S Yu, Y Jeon, T K Kim
We studied the predictive performance of the Minto pharmacokinetic model during cardiopulmonary bypass in patients undergoing cardiac surgery. Patients received remifentanil target-controlled infusion using the Minto model during total intravenous anaesthesia with propofol. From 56 patients, 275 arterial blood samples were drawn before, during and after bypass to determine the plasma concentration of remifentanil, and the predicted concentrations were recorded at each time. For pooled data, the median prediction error and median absolute prediction error were 21...
October 2017: Anaesthesia
https://www.readbyqxmd.com/read/28877511/severe-neurotoxicity-requiring-mechanical-ventilation-in-a-dog-envenomed-by-a-red-bellied-black-snake-pseudechis-porphyriacus-and-successful-treatment-with-an-experimental-bivalent-whole-equine-igg-antivenom
#5
A M Padula, E M Leister
Snakebite in dogs from Pseudechis porphyriacus (red-bellied black snake; RBBS) is a common envenomation treated by veterinarians in Australia where this snake occurs. This case report describes the successful treatment of a clinically severe RBBS envenomation in a dog with an experimental bivalent equine whole IgG antivenom and mechanical ventilation, following its presentation in a cyanotic state. The cause of the cyanosis and respiratory distress was considered due to paralysis from neurotoxins in RBBS venom...
September 4, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28876566/a-survey-of-selected-key-areas-of-management-of-south-african-neurosurgical-patients
#6
C H Daniel, M D du Trevou
BACKGROUND: Previous surveys of neurosurgical patient management, including a South African (SA) survey conducted in 2001, confirmed the existence of significant dissimilarities in management on national and international levels. This survey aimed to determine current SA neurosurgical patient management and to compare this with international trends. METHOD: Questionnaires in multiple choice question (MCQ) and free text entry format covering key areas of neurosurgical practice were emailed to SA neurosurgeons following ethics approval...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28873076/women-awaken-faster-than-men-after-electroencephalogram-monitored-propofol-sedation-for-colonoscopy-a-prospective-observational-study
#7
Andrea Riphaus, Mark Slottje, Jan Bulla, Carolin Keil, Christian Mentzel, Vera Limbach, Barbara Schultz, Christian Unzicker
BACKGROUND: Sedation for colonoscopy using intravenous propofol has become standard in many Western countries. OBJECTIVE: Gender-specific differences have been shown for general anaesthesia in dentistry, but no such data existed for gastrointestinal endoscopy. DESIGN: A prospective observational study. SETTING: An academic teaching hospital of Hannover Medical School. PATIENTS: A total of 219 patients (108 women and 111 men) scheduled for colonoscopy...
October 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28863931/diabetes-mellitus-does-not-affect-the-neuromuscular-blocking-action-of-atracurium-in-dogs
#8
Elizabeth A Leece, Louise Clark
OBJECTIVE: To compare the duration of action of atracurium in diabetic and nondiabetic dogs. STUDY DESIGN: Prospective, blinded, clinical study. ANIMALS: A total of 26 diabetic and 29 nondiabetic dogs. METHODS: Following preanaesthetic medication and intravenous (IV) propofol induction, anaesthesia was maintained with isoflurane in oxygen. Atracurium 0.2 mg kg(-1) IV was administered to provide neuromuscular blockade (NMB) and the responses (twitches; T) to train-of-four nerve stimulation were recorded by palpation and electromyography (EMG)...
April 25, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28844293/the-effect-of-maropitant-on-intraoperative-isoflurane-requirements-and-postoperative-nausea-and-vomiting-in-dogs-a-randomized-clinical-trial
#9
Adam Swallow, Eva Rioja, Tim Elmer, Alex Dugdale
OBJECTIVE: To establish if preoperative maropitant significantly reduced intraoperative isoflurane requirements and reduced clinical signs associated with postoperative nausea and vomiting (PONV) in dogs. STUDY DESIGN: Randomized clinical trial. ANIMALS: Twenty-four healthy, client-owned dogs undergoing routine ovariohysterectomy. METHODS: Premedication involved acepromazine (0.03 mg kg(-1)) combined with methadone (0...
April 12, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28827993/comparative-experimental-study-on-two-designed-intravenous-anaesthetic-combinations-in-dogs
#10
Abdelnaser Abdelmoneim Azab Abdel-Hady, Khaled M Abdelbasset, Ahmed S Soliman
The goal of the present study is to design a good anaesthetic program for dogs which can lead to optimal anaesthesia with no or minimal post-operative adverse effects. For this purpose, we designed two anaesthetic combinations and compared their effects in Mongrel dogs: combination 'A' consisting of atropine, xylazine, ketamine plus propofol, and combination 'B' consisting of atropine, diazepam, ketamine plus propofol. The onset and duration of anaesthesia induction, the duration of maintenance as well as the period of recovery were recorded and compared for both combinations...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28814306/blood-acid-base-status-in-impala-aepyceros-melampus-immobilised-and-maintained-under-total-intravenous-anaesthesia-using-two-different-drug-protocols
#11
Gareth E Zeiler, Leith C R Meyer
BACKGROUND: In mammals, homeostasis and survival are dependent on effective trans-membrane movement of ions and enzyme function, which are labile to extreme acid-base changes, but operate efficiently within a narrow regulated pH range. Research in patients demonstrating a pH shifts outside the narrow regulated range decreased the cardiac output and systemic vascular resistance and altered the oxygen binding to haemoglobin. These cardiopulmonary observations may be applicable to the risks associated with anaesthesia and performance of wildlife ungulates on game farms...
August 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28764270/feasibility-and-complications-of-spinal-anaesthesia-in-percutaneous-nephrolithotomy-our-experience
#12
Manoj Kamal, Pradeep Sharma, Geeta Singariya, Rajesh Jain
INTRODUCTION: Percutaneous Nephrolithotomy (PCNL) is the treatment modality used for the extraction of large renal stones, or multiple calculi or stones resistant to shock wave lithotripsy. The General Anaesthesia (GA) is the standard modality for PCNL. However, few studies conclude that Spinal Anaesthesia (SA) can be an alternative method of anaesthesia with similar incidence of complications. AIM: In our study we evaluated the feasibility of spinal anaesthesia in terms of intraoperative and postoperative results in patients undergoing PCNL...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28760591/the-hairy-lizard-heterothermia-affects-anaesthetic-requirements-in-the-arabian-oryx-oryx-leucoryx
#13
Mads F Bertelsen, Osama Mohammed, Tobias Wang, Paul R Manger, David Michael Scantlebury, Khairi Ismael, Nigel C Bennett, Abdulaziz Alagaili
OBJECTIVE: To study the effect of heterothermia on anaesthetic drug requirements in semi-free ranging Arabian oryx and to assess the temperature quotient (Q10) of oxygen consumption. STUDY DESIGN: Prospective observational study and controlled metabolic experiment. ANIMALS: Sixty-eight anaesthetic events in 59 Arabian oryx from Mahazat As-Sayd protected area, Saudi Arabia METHODS: Anaesthesia was induced by remote injection of 25 mg ketamine, 10 mg midazolam and 0...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28744857/the-effect-of-pre-operative-methylprednisolone-on-early-endothelial-damage-after-total-knee-arthroplasty-a-randomised-double-blind-placebo-controlled-trial
#14
V Lindberg-Larsen, S R Ostrowski, M Lindberg-Larsen, M L Rovsing, P I Johansson, H Kehlet
We wished to evaluate whether inhibition of the systemic inflammatory response by a single pre-operative dose of methylprednisolone reduced markers of early endothelial damage after fast-track total knee arthroplasty. We randomly allocated 70 patients undergoing elective unilateral total knee arthroplasty (1:1) to receive either pre-operative intravenous methylprednisolone 125 mg (methylprednisolone group) or isotonic saline (control group). All procedures were performed under spinal anaesthesia without a tourniquet, using a standardised multimodal analgesic regime...
July 26, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28741744/thermal-suit-in-preventing-unintentional-intraoperative-hypothermia-during-general-anaesthesia-a-randomized-controlled-trial
#15
S-L Lauronen, M-L Kalliomäki, A J Aho, J Kalliovalkama, J M Riikonen, M-T Mäkinen, H M Leppikangas, A M Yli-Hankala
BACKGROUND: Unintentional perioperative hypothermia causes serious adverse effects to surgical patients. Thermal suit (T-Balance(®) ) is an option for passive warming perioperatively. We hypothesized that the thermal suit will not maintain normothermia more efficiently than conventional cotton clothes when also other preventive procedures against unintentional hypothermia are used. METHODS: One hundred patients were recruited to this prospective, randomized trial...
July 25, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28739108/use-of-cis-atracurium-to-maintain-moderate-neuromuscular-blockade-in-experimental-pigs
#16
Alexandru Tutunaru, Julien Dupont, Vincent Huberty, Mostafa Ibrahim, Didier Serteyn, Charlotte Sandersen
OBJECTIVE: To determine the dose of cis-atracurium needed to produce a moderate neuromuscular blockade (NMB) in pigs. STUDY DESIGN: Prospective experimental study. ANIMALS: Seven pigs [five females and two males; median (range) body weight: 47 (36-64) kg]. METHODS: Pigs were premedicated with intramuscular midazolam (0.3 mg kg(-1)) and ketamine (7 mg kg(-1)). Anaesthesia was induced with intravenous (IV) propofol 3 (1-4) mg kg(-1) and maintained with isoflurane in oxygen...
April 15, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28719515/anaesthetic-management-of-patients-with-myopathies
#17
Mark Schieren, Jerome Defosse, Andreas Böhmer, Frank Wappler, Mark U Gerbershagen
: The anaesthetic management of patients with myopathies is challenging. Considering the low incidence and heterogeneity of these disorders, most anaesthetists are unfamiliar with key symptoms, associated co-morbidities and implications for anaesthesia. The pre-anaesthetic assessment aims at the detection of potentially undiagnosed myopathic patients and, in case of known or suspected muscular disease, on the quantification of disease progression. Ancillary testing (e.g. echocardiography, ECG, lung function testing etc...
October 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28716685/the-use-of-alfaxalone-for-premedication-induction-and-maintenance-of-anaesthesia-in-pigs-a-pilot-study
#18
Sarah E Bigby, Jennifer E Carter, Sébastien Bauquier, Thierry Beths
OBJECTIVE: The evaluation of alfaxalone as a premedication agent and intravenous anaesthetic in pigs. STUDY DESIGN: Prospective, clinical trial. ANIMALS: Nine healthy, 6-8-week-old female Landrace pigs weighing 22.2 ± 1.0 kg, undergoing epidural catheter placement. METHODS: All pigs were premedicated with 4 mg kg(-1) alfaxalone, 40 μg kg(-1) medetomidine and 0.4 mg kg(-1) butorphanol administered in the cervical musculature...
March 21, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28707737/-18-f-sodium-fluoride-positron-emission-tomography-of-the-equine-distal-limb-exploratory-study-in-three-horses
#19
M Spriet, P Espinosa, A Z Kyme, K L Phillips, S A Katzman, L D Galuppo, P Stepanov, D Beylin
BACKGROUND: Positron emission tomography (PET) is a cross-sectional, functional imaging modality that has recently become available to the horse. The use of (18) F-sodium fluoride ((18) F-NaF), a PET bone tracer, has not previously been reported in this species. OBJECTIVES: To assess the feasibility of (18) F-NaF PET in the equine distal limb and explore possible applications in the horse in comparison with other imaging modalities. STUDY DESIGN: Exploratory descriptive study involving three research horses...
July 14, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28707325/effects-of-scalp-nerve-block-on-pain-and-emergence-agitation-after-paediatric-nevus-surgery-a-clinical-trial
#20
J-S Kim, G W Kim, D H Park, H E Ahn, M Y Chang, J Y Kim
BACKGROUND: Pain is considered as being one cause of post-operative emergence agitation (EA) from sevoflurane anaesthesia. The purpose of this study was to investigate the pure effect of post-operative pain on EA after sevoflurane anaesthesia in preschool children undergoing excision of scalp nevi. METHODS: Forty-four children, 1-7 years old, undergoing scalp nevus excision were enrolled. Patients were randomly assigned to two groups: the remifentanil group received single intravenous injection of short-acting synthetic opioid, remifentanil 1 μg/kg just before the scalp incision, and the block group received scalp nerve block with 0...
September 2017: Acta Anaesthesiologica Scandinavica
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