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penetrating keratoplasty

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https://www.readbyqxmd.com/read/28225198/adjunctive-steroid-therapy-versus-antibiotics-alone-for-acute-endophthalmitis-after-intraocular-procedure
#1
REVIEW
Carole H Kim, Monica F Chen, Anne L Coleman
BACKGROUND: Endophthalmitis refers to severe infection within the eye that involves the aqueous humor or vitreous humor, or both, and threatens vision. Most cases of endophthalmitis are exogenous (i.e. due to inoculation of organisms from an outside source), and most exogenous endophthalmitis is acute and occurs after an intraocular procedure. The mainstay of treatment is emergent administration of broad-spectrum intravitreous antibiotics. Due to their anti-inflammatory effects, steroids in conjunction with antibiotics have been proposed to be beneficial in endophthalmitis management...
February 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28224301/surgical-outcomes-of-perforated-and-unperforated-corneal-descemetocele
#2
Evin Singar Ozdemir, Ayse Burcu, Zuleyha Yalnız Akkaya, Firdevs Ornek
OBJECTIVE: To compare the surgical outcomes of amniotic membrane transplantation (AMT) and penetrating keratoplasty (PK) in perforated and non-perforated corneal descemetocele. METHOD: In this study, we retrospectively examined 48 eyes of 48 patients operated with AMT, and 32 eyes of 32 patients operated with PK for perforated and non-perforated descemetocele. RESULTS: There were no significant differences between the two groups with regard to age, sex, laterality, follow-up duration, cause of descemetocele, and localization (p > 0...
February 21, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28192842/-keratoplasty-in-children-and-adolescents
#3
S J Lang, C Richter, O Richter, D Böhringer, G Geerling, T Reinhard
Background The conditions for long-term graft survival in infants and children are unfavorable, due to the different immunological features, the impaired clinical examination and the reduced compliance and treatment adherence. However, penetrating keratoplasty is often the only option to prevent amblyopia and there may be no alternative. We examined the different indications, graft survival and complications in two specialised centres. Material and Methods We identified all patients who were under the age of 18 years at the time of their penetrating keratoplasty...
February 13, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28179383/cultivated-limbal-epithelial-transplantation-and-penetrating-keratoplasty-postchemical-injury-a-14-year-follow-up
#4
Ritu Shah, Charuta Puranik, Ashik Mohamed, Virender S Sangwan
An 11-year-old girl presented to our tertiary eye care centre with a 9-month-old history of lime injury in the left eye in 1999 with vision of counting fingers close to the face. She initially underwent superficial keratectomy with amniotic membrane graft in 1999. Subsequently, cultivated limbal epithelial transplantation was performed in 2001 which improved her vision to 20/400. Following development of pannus and symblepharon in the left eye, she underwent pannus resection and conjunctival limbal autograft in 2002 and, a month later, optical penetrating keratoplasty (PK) following which her vision improved to 20/125...
February 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28160068/descemet-membrane-endothelial-keratoplasty-for-graft-failure-following-penetrating-keratoplasty
#5
Sonja Heinzelmann, Daniel Böhringer, Philipp Eberwein, Thabo Lapp, Thomas Reinhard, Philip Maier
PURPOSE: Descemet membrane endothelial keratoplasty (DMEK) is superior to penetrating keratoplasty (PK) in terms of visual rehabilitation, intraoperative safety and risk of rejection. Therefore, it seems reasonable to perform DMEK in eyes with endothelial failure following PK. We herein report our first clinical results. METHODS: Nineteen eyes with endothelial graft failure following PK were treated with DMEK. The majority of these eyes (12) had limited visual potential...
February 3, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28151861/shifting-trends-in-microbial-keratitis-following-penetrating-keratoplasty-in-taiwan
#6
Hung-Chi Chen, Chia-Yi Lee, Hung-Yu Lin, David Hui-Kang Ma, Phil Yeong-Fong Chen, Ching-Hsi Hsiao, Hsin-Chiung Lin, Lung-Kun Yeh, Hsin-Yuan Tan
To investigate the clinical and microbiological profiles from microbial keratitis following penetrating keratoplasty (PKP) in a tertiary referral center in Taiwan, the medical records of 648 consecutive patients (648 eyes) undergoing PKP between January 2003 and December 2007 were retrospectively reviewed. Patients who subsequently sustained microbial keratitis were enrolled and analyzed for potential risk factors, clinical manifestations, microbiological profiles, complications, graft survival, and final visual outcome...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28151811/effect-of-trabeculotomy-on-corneal-endothelial-cell-loss-in-cases-of-after-penetrating-keratoplasty-glaucoma
#7
Ayaka Kusakabe, Naoki Okumura, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Noriko Koizumi, Chie Sotozono, Shigeru Kinoshita, Kazuhiko Mori
PURPOSE: The aim of this study was to evaluate the effect of trabeculotomy (TLO) on glaucoma and endothelial cell loss after penetrating keratoplasty (PK). METHODS: A retrospective study was conducted on consecutive patients who underwent PK and in whom more than 24 months of follow-up was available. Patients were categorized into the PK+TLO group [ie, TLO for post-PK glaucoma (n = 10)] and the PK group [PK alone (n = 73)]. Intraocular pressure (IOP) was evaluated during each follow-up examination...
March 2017: Cornea
https://www.readbyqxmd.com/read/28138772/effect-of-corneal-collagen-crosslinking-on-subsequent-deep-anterior-lamellar-keratoplasty-dalk-in-keratoconus
#8
Friederike Schaub, Philip Enders, Björn O Bachmann, Ludwig M Heindl, Claus Cursiefen
PURPOSE: The purpose was to investigate the impact of ultraviolet light corneal collagen crosslinking (UV-CXL) on the success rate and clinical outcome of subsequent deep anterior lamellar keratoplasty (DALK) in eyes with keratoconus (KC). METHODS: Medical records of 101 consecutive eyes with KC scheduled for big-bubble DALK surgery were screened retrospectively for details of previously performed UV-CXL, as well as intra- and postoperative complications of DALK surgery...
January 30, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28129297/toxic-anterior-segment-syndrome-inadvertent-administration-of-intracameral-lidocaine-1-and-phenylephrine-2-5-preserved-with-10-benzalkonium-chloride-during-cataract-surgery
#9
Brett P Bielory, Ayesha Shariff, Rehan M Hussain, Jose Antonio Bermudez-Magner, Sander R Dubovy, Kendall E Donaldson
PURPOSE: To report 3 patients with corneal decompensation and anterior uveitis within 24 hours of cataract surgery from a single ambulatory surgery center using intracameral lidocaine HCl 1% and phenylephrine 2.5% inadvertently preserved with 10% benzalkonium chloride. METHODS: This case series describes 3 patients who underwent traditional cataract extraction with a significant decrease in visual acuity in the immediate postoperative period resulting in secondary surgical intervention for corneal decompensation in 2 patients...
January 26, 2017: Cornea
https://www.readbyqxmd.com/read/28129295/asymptomatic-infection-in-decompensated-full-thickness-corneal-grafts-referred-for-repeat-penetrating-keratoplasty
#10
Yoav Nahum, Pia Leon, Benedetta Azzurra Ricci-Filipovic, Davide Camposampiero, Diego Ponzin, Massimo Busin
PURPOSE: We report a case series of asymptomatic infections affecting failed corneal grafts in patients referred for repeat penetrating keratoplasty (PK). METHODS: In this retrospective, noncomparative, interventional case series, we reviewed the medical records of all repeat PK procedures performed at Villa Serena-Villa Igea private Hospitals (Forlì, Italy) between January 2011 and March 2016. Specifically, preoperative and postoperative slit-lamp examinations, and the results of histological and bacteriological examinations, were noted...
January 26, 2017: Cornea
https://www.readbyqxmd.com/read/28116630/corneal-transplantation-study-of-the-data-of-a-regional-eye-bank-for-the-year-2013-and-analysis-of-the-evolution-of-the-adverse-events-reported-in-france-since-2010
#11
Anne-Sophie Gauthier, Marie Castelbou, Mélanie Bidaut Garnier, Joëlle Pizzuto, Stephan Roux, Philippe Gain, Fabienne Pouthier, Bernard Delbosc
To analyze the data of the adverse events collected in a single major eye bank (EFS Bourgogne Franche Comté, Besançon, France) for the year 2013 and to report the French data of biovigilance provided by the French National Agency for Medicines and Health Products Safety (ANSM) between 2010 and 2013. we have set up a study of adverse events in 2013, in collaboration with a single eye bank (EFS Bourgogne Franche Comté, Besançon, France). A survey was sent to the surgeon for each delivered corneal button by the eye bank in 2013...
January 23, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28114585/immune-cells-on-the-corneal-endothelium-of-an-allogeneic-corneal-transplantation-rabbit-model
#12
Elena Koudouna, Naoki Okumura, Yugo Okazaki, Shinichiro Nakano, Ryota Inoue, Nigel J Fullwood, Junko Hori, Shigeru Kinoshita, Noriko Koizumi
Purpose: Corneal endothelial cell density undergoes a progressive decrease for many years after transplantation, eventually threatening patients with late endothelial failure. The purpose of this study was to investigate the possibility of an immunologic response in successfully grafted corneal endothelium. Methods: The corneal endothelium of patients who had undergone corneal transplantation was evaluated by specular microscopy. Rabbit models were subjected to penetrating keratoplasty (PK) with either syngeneic or allogeneic corneal transplants and Descemet's stripping endothelial keratoplasty (DSEK) with allogeneic corneal transplants...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28114570/sustained-subconjunctival-delivery-of-infliximab-protects-the-cornea-and-retina-following-alkali-burn-to-the-eye
#13
Chengxin Zhou, Marie-Claude Robert, Vassiliki Kapoulea, Fengyang Lei, Anna M Stagner, Frederick A Jakobiec, Claes H Dohlman, Eleftherios I Paschalis
Purpose: Tumor necrosis factor (TNF)-α is upregulated in eyes following corneal alkali injury and contributes to corneal and also retinal damage. Prompt TNF-α inhibition by systemic infliximab ameliorates retinal damage and improves corneal wound healing. However, systemic administration of TNF-α inhibitors carries risk of significant complications, whereas topical eye-drop delivery is hindered by poor ocular bioavailability and the need for patient adherence. This study investigates the efficacy of subconjunctival delivery of TNF-α antibodies using a polymer-based drug delivery system (DDS)...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28079690/noncontact-evaluation-of-corneal-grafts-swept-source-fourier-domain-oct-versus-high-resolution-scheimpflug-imaging
#14
Eszter Szalai, Gábor Németh, Ziad Hassan, László Módis
PURPOSE: To study the reliability and repeatability of anterior segment measurements in patients who underwent penetrating keratoplasty with swept light source Fourier domain anterior segment optical coherence tomography (SS-OCT) in comparison with a high-resolution Scheimpflug camera. METHODS: Keratometry (K) and elevation data of the anterior and posterior corneal surfaces, central corneal thickness, and anterior chamber depth were determined in 56 postkeratoplasty eyes (mean age: 59...
January 11, 2017: Cornea
https://www.readbyqxmd.com/read/28079685/asymmetric-deep-stromal-keratopathy-in-a-patient-with-multiple-myeloma
#15
Laurel T Tainsh, Patrick A Coady, John H Sinard, Natalia Neparidze, Seth W Meskin, Ron A Adelman, Jessica Chow
PURPOSE: To report a case of asymmetric deep stromal keratopathy in a patient with multiple myeloma. METHODS: Case report and literature review. RESULTS: An 85-year-old woman was found to have progressive visually significant left-sided deep stromal opacity in the setting of monoclonal gammopathy. Hematologic workup resulted in a diagnosis of IgG kappa multiple myeloma. Histopathology was significant for semicrystalline deposits in the posterior stroma...
March 2017: Cornea
https://www.readbyqxmd.com/read/28079683/factors-associated-with-graft-detachment-after-primary-descemet-stripping-automated-endothelial-keratoplasty
#16
Yoav Nahum, Pia Leon, Michael Mimouni, Massimo Busin
PURPOSE: To identify risk factors associated with postoperative graft detachment after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: In this retrospective institutional cohort study, the study group included all consecutive eyes that underwent primary DSAEK between January 2005 and October 2015 at Villa Serena-Villa Igea private hospitals (Forlì, Italy) and developed postoperative graft detachment (n = 45). The control group included all eyes that underwent primary DSAEK during the same period and did not develop graft detachment (n = 1167)...
March 2017: Cornea
https://www.readbyqxmd.com/read/28076564/atopic-keratoconjunctivitis-long-term-results-of-medical-treatment-and-penetrating-keratoplasty
#17
Yusuf Koçluk, Zuleyha Yalniz-Akkaya, Ayşe Burcu, Firdevs Örnek
Purpose: To evaluate the long-term outcomes of medically or surgically treated patients with atopic keratoconjunctivitis (AKC). Methods: Charts of 16 patients with AKC (32 eyes) observed between 1996 and 2013 were reviewed retrospectively. Outcome measures included demographic features, follow-up duration, and biomicroscopic findings at the first and most recent visits. The corrected distance visual acuity (CDVA; in decimal units) was evaluated at the initial visit and the 1-, 6-, and 12-month follow-up visits...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28076561/visual-outcomes-after-deep-anterior-lamellar-keratoplasty-using-donor-corneas-without-removal-of-descemet-membrane-and-endothelium
#18
Tatiana Moura Bastos Prazeres, Rodrigo Muller, Tatiana Rayes, Flavio Eduardo Hirai, Luciene Barbosa de Sousa
Purpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28060143/comparison-of-hospital-cornea-retrieval-and-voluntary-eye-donation-program-in-eye-banking
#19
Namrata Sharma, Nikhil Agrawal, Prafulla K Maharana, Tushar Agarwal, Murugesan Vanathi, Rasik B Vajpayee
OBJECTIVES: Comparison of demographic, clinical, microbiological, and utility profile of the corneas obtained through hospital corneal retrieval program (HCRP) and voluntary eye donation (VED) program. METHODS: Donor corneas retrieved during a 14 months period at National eye bank, India were included in the study. The donor cornea grading was done according to the cornea donor study. The corneal swabs were taken from the donor eyes and were sent for microbiological evaluation...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28060057/trends-in-corneal-transplantation-in-keratoconus
#20
Daniel Sarezky, Stephen E Orlin, Wei Pan, Brian L VanderBeek
PURPOSE: To determine recent trends in and sociodemographic/comorbid conditions associated with penetrating keratoplasty (PK) and lamellar keratoplasty (LK) for keratoconus (KCN). METHODS: Patients with KCN and subsequent PK and LK procedures were identified using International Classification of Diseases, 9th revision (ICD-9) and Current Procedural Terminology (CPT) billing codes. The change in surgical rates was calculated over a decade, and multivariate analysis demonstrated factors associated with undergoing surgery...
2017: Cornea
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