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penetrating keratoplasty

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https://www.readbyqxmd.com/read/29649920/corneal-transplantation-trends-in-france-from-2004-to-2015-a-12-year-review
#1
Guillaume Bigan, Marc Puyraveau, Maher Saleh, Philippe Gain, Isabelle Martinache, Bernard Delbosc, Anne-Sophie Gauthier
PURPOSE: The aim of this study was to report the 12-year longitudinal trends in indication and corneal transplantation techniques in France from 2004 to 2015. RESULTS: The records of all corneal transplantations performed from 2004 to 2015 in France were retrospectively reviewed. The patient indications and types of transplant performed were analyzed. A total of 46,658 corneal transplantations were performed between 2004 and 2015, with 34,187 (73.3%) penetrating keratoplasty and 10,452 (22...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29643713/modified-conjunctival-flap-as-a-primary-procedure-for-nontraumatic-acute-corneal-perforation
#2
Yi-Chen Sun, Jason P Kam, Tueng T Shen
Objective: Appropriate management of nontraumatic acute corneal perforation is always a challenge even with the many advances in surgical materials and techniques. We reported the outcomes of a case series of acute corneal perforation repair using a newly modified conjunctival flap with amniotic membrane transplant (AMT), fibrin glue, and a bandage soft contact lens (BCL). Materials and Methods: A total of 13 consecutive referral cases with nontraumatic acute corneal perforation at the University of Washington were reviewed...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29615834/corneal-clarity-measurements-in-patients-with-keratoconus-undergoing-either-penetrating-or-deep-anterior-lamellar-keratoplasty
#3
Khaled Alzahrani, Syarifah-Faiza Dardin, Fiona Carley, Arun Brahma, Debbie Morley, M Chantal Hillarby
Purpose: To compare the corneal clarity measurement between penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) in patients with keratoconus, using densitometry software for the Oculus Pentacam. Methods: A retrospective comparative study was carried out at Manchester Royal Eye Hospital. Data were collected 12-18 months after corneal transplantation for keratoconus, including postoperative corneal densitometry, best corrected visual acuity (BCVA), central corneal thickness (CCT), and other relevant clinical details...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29607781/effect-of-donor-cornea-on-the-surgical-outcomes-of-penetrating-keratoplasty-imported-cornea-versus-domestic-cornea
#4
Evin Singar-Ozdemir, Ayse Burcu, Baris Oral, Zuleyha Yalniz-Akkaya, Selma Uzman, Sema Tamer Kaderli, Firdevs Ornek
OBJECTIVES: In this study, we compared the surgical outcomes of penetrating keratoplasty using domestic and imported donor corneas. MATERIALS AND METHODS: We retrospectively evaluated 200 eyes and 200 consecutive patients who underwent penetrating keratoplasty by using domestic and imported donor corneas between January 2013 and December 2013. The donor characteristics, preoperative clinical features, and clinical outcomes at 6, 12, 24, and 36 months were assessed...
April 2, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29604391/macular-corneal-dystrophy-a-review
#5
REVIEW
Shruti Aggarwal, Travis Peck, Jeffrey Golen, Zeynel A Karcioglu
Macular corneal dystrophy (MCD) is a corneal stromal dystrophy which leads to progressive vision loss. MCD is an autosomal recessive condition in which there is abnormality of proteoglycan synthesis. Mutations in the carbohydrate sulphotransferase gene (CHST6) prevent normal sulfation of corneal keratan. Different immunophenotypes have been described depending on the presence of keratan sulfate in cornea and or serum. The deposition of abnormal proteoglycans leads to loss of corneal transparency and decreased vision...
March 28, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29601364/corneal-cross-linking-for-pediatric-keratcoconus-review
#6
Claudia Perez-Straziota, Ronald N Gaster, Yaron S Rabinowitz
PURPOSE: To comprehensively review the available published literature for cross-linking in the pediatric population. METHODS: Review of the literature published in English in PubMed. RESULTS: Two hundred ten publications were considered. One hundred fifteen were considered relevant to this review. CONCLUSIONS: Studies of cross-linking in pediatric patients are sparse, with relatively short follow-up times, and mostly on small groups of patients...
March 28, 2018: Cornea
https://www.readbyqxmd.com/read/29601363/outcomes-of-trabeculectomy-and-glaucoma-drainage-devices-for-elevated-intraocular-pressure-after-penetrating-keratoplasty
#7
Mehmet Yakin, Umit Eksioglu, Zuleyha Yalniz-Akkaya, Selma Uzman, Evin Singar-Ozdemir, Kemal Gultekin, Gulizar Demirok, Ilgaz Yalvac, Firdevs Ornek, Ayse Burcu
PURPOSE: To assess and compare the outcomes of trabeculectomy with and without antimetabolites (AMs) and glaucoma drainage devices (GDDs) in the management of elevated intraocular pressure (IOP) after penetrating keratoplasty (PK). METHODS: Data of 84 eyes of 81 patients who underwent trabeculectomy (12 eyes without an AM and 42 eyes with an AM) or GDD implantation (30 eyes) after PK were reviewed retrospectively. The main outcome measures were IOP control, corneal graft survival, and postoperative ocular complications...
March 28, 2018: Cornea
https://www.readbyqxmd.com/read/29595762/transplantation-blues-inadvertent-staining-of-amyloid-deposits-with-trypan-blue
#8
Agathe Marcon, Nicolas Périllat, Thibaud Garcin, Rémy Jullienne, Zhiguo He, Fabien Forest, Anne Sophie Gauthier, Philippe Gain, Gilles Thuret
PURPOSE: To describe inadvertent persistent staining of stromal amyloid deposits by trypan blue (TB) after penetrating keratoplasty (PK) and Descemet membrane endothelial keratoplasty (DMEK) performed in patients with corneal amyloidosis. METHODS: Case series of patients with corneal amyloidosis in whom intraoperative TB was used. RESULTS: One patient, hospitalized for acute rejection 6 weeks after DMEK, presented with an intense blue staining of small, spindle-shaped structures in the anterior half of the cornea...
March 27, 2018: Cornea
https://www.readbyqxmd.com/read/29588822/candida-albicans-endophthalmitis-following-penetrating-keratoplasty-a-case-report
#9
Shahram Bamdad, Aidin Meshksar, Mohammad Mostafa Safarpour
Endophthalmitis is one of the most serious complications of intraocular surgeries, and Candida albicans constitutes the majority of cases of post penetrating keratoplasty (PK) endophthalmitis. The presenting case is a 21-year-old woman with known case of advanced keratoconus and vernal keratoconjunctivitis who underwent PK, and developed recalcitrant anterior uveitis and subsequent whitish lesion on the superonasal of the lens. She was on topical steroids with possible impression of Uretts Zavalia syndrome versus phacoantigenic uveitis following traumatic cataract up to the 50th day of post operation that manifested symptoms of frank endophthalmitis; and underwent deep vitrectomy, lensectomy, localized iridectomy and irrigation with diluted Imipenem and Amphotericin-B...
January 2018: Electronic Physician
https://www.readbyqxmd.com/read/29573998/painless-bilateral-bullous-keratopathy
#10
Stephen J Vincent
Bullous keratopathy is a pathological corneal condition that arises due to irreversible oedema associated with endothelial cell loss or dysfunction. Symptoms may vary from mild (transient blurred vision and increased glare from epithelial oedema) to severe (an acute and significant loss of vision associated with frank endothelial decompensation, and pain due to ruptured epithelial bullae). Possible treatments to restore vision and minimise pain include topical hypertonic agents, bandage contact lenses, superficial anterior corneal surgical procedures or penetrating full thickness or endothelial keratoplasty...
March 21, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29572164/surgical-management-of-severe-ocular-surface-injury-due-to-roman-candle-explosion-accidents
#11
Albert Y Cheung, Brad M Genereux, Brittney Dautremont, Amit Govil, Edward J Holland
PURPOSE: To report the clinical features, management, and outcomes of patients with ocular surface damage secondary to Roman candle explosion accidents. METHODS: Retrospective, noncomparative, interventional case series of 11 patients with Roman candle explosion-related ocular surface injuries referred to the Cincinnati Eye Institute between 2007 and 2016. RESULTS: Eleven patients (10 male, 1 female, mean age 22.4 years) sustained unilateral ocular surface injuries with presenting visual acuity ranging from count fingers to light perception...
March 20, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29565715/dacryoadenitis-due-to-gonococcal-conjunctivitis-complicated-by-corneal-perforation
#12
Thomas L Jenkins, Matthew M Zhang, Neal S Patel, Alison B Huggins, Jacqueline R Carrasco
Adnexal and periocular involvement in Neisseria gonorrhoeae (NG) infection is rare. This report describes the case of a patient with a delayed diagnosis of gonococcal dacryoadenitis with contiguous conjunctivitis and corneal involvement. She underwent extensive inpatient laboratory and infectious workup but rapidly progressed to corneal perforation requiring emergent penetrating keratoplasty prior to a positive culture confirming the diagnosis. To date, this is the first reported case of ophthalmologic NG infection with associated conjunctivitis, dacryoadenitis, and corneal perforation...
March 22, 2018: Orbit
https://www.readbyqxmd.com/read/29564359/femtosecond-laser-assisted-astigmatic-keratotomy-a-review
#13
REVIEW
John S M Chang
Background: Astigmatic keratotomy (AK) remains an accessible means to correct surgically induced or naturally occurring astigmatism. The advantages of femtosecond laser-assisted astigmatic keratotomy (FSAK) over conventional methods have been recognized recently. Main text: This review evaluates the efficacy, complications, and different methods of FSAK for correction of astigmatism in native eyes and those that underwent previous penetrating keratoplasty (PKP)...
2018: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/29555247/post-keratoplasty-endophthalmitis-by-multidrug-resistant-pseudomonas-aeruginosa-with-positive-culture-of-the-contralateral-donor-cornea-a-case-report
#14
J C Serna-Ojeda, L Pedro-Aguilar, C Rodriguez-Quintanilla, H Mejía-López, D G Ponce-Angulo, A Navas, V M Bautista-de Lucio, E O Graue-Hernandez
PURPOSE: The aim of this paper is to present the case report of a patient developing endophthalmitis after penetrating keratoplasty caused by a multidrug-resistant Pseudomonas aeruginosa, detected only in the contralateral donor tissue. CASE REPORT: A 77-year-old man underwent an uneventful penetrating keratoplasty with a preoperative culture-negative donor cornea; however, the fellow cornea grew multidrug-resistant Pseudomonas aeruginosa. The patient developed and was treated for endophthalmitis after penetrating keratoplasty, and aqueous and vitreous taps grew P...
March 16, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29553466/effect-of-intracameral-ophthalmic-cefuroxime-solution-aprokam-%C3%A2-in-the-prophylaxis-of-cataract-surgery-in-patients-with-keratoplasty
#15
Mustafa Erdoğan Cicik, Cezmi Doğan, Osman Şevki Arslan
BACKGROUND: Development of endophthalmitis during cataract surgery is one of the most severe complications and it may also result in blindness and globe loss. AIMS: To evaluate the effect of an ophthalmic cefuroxime solution (Aprokam® ) that is prophylactically used in phacoemulsification surgery performed due to cataract that eventually occurs in patients with or without penetrating keratoplasty. STUDY DESIGN: Case-control study. METHODS: In this retrospective study, patients who had undergone penetrating keratoplasty and for whom phacoemulsification surgery was performed due to cataract and an intracameral ophthalmic cefuroxime solution (Aprokam® ) was administered for prophylaxis were evaluated in comparison with patients with cataract without keratoplasty...
March 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29552670/endophthalmitis-caused-by-gram-positive-bacteria-resistant-to-vancomycin-clinical-settings-causative-organisms-antimicrobial-susceptibilities-and-treatment-outcomes
#16
Hegde Sharat Shivaramaiah, Nidhi Relhan, Avinash Pathengay, Nitin Mohan, Harry W Flynn
Purpose: To report the clinical settings, causative organisms, antimicrobial susceptibilities, and treatment outcomes of patients with endophthalmitis caused by gram-positive bacteria resistant to vancomycin. Methods: Retrospective case series of all patients with culture-proven endophthalmitis caused by gram-positive bacteria resistant to vancomycin between January 2010 and December 2016 in LV Prasad Eye Institute, Visakhapatnam, India. Results: The current study included 14 patients...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29550189/long-term-functional-and-anatomical-outcomes-of-repeat-graft-after-optically-failed-therapeutic-keratoplasty
#17
Dubbaka Srujana, Manpreet Kaur, Jayanand Urkude, Anubha Rathi, Namrata Sharma, Jeewan S Titiyal
PURPOSE: To evaluate the functional and anatomical outcomes of repeat penetrating keratoplasty (PK) in optically failed therapeutic grafts. DESIGN: Prospective interventional case series METHODS: All cases admitted at the apex tertiary care centre for repeat keratoplasty following optically failed therapeutic PK were enrolled over a period of one year. Repeat optical PK was performed in all eyes. Primary outcome measures were postoperative graft clarity and visual acuity...
March 14, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29545414/leap-forward-in-the-treatment-of-pythium-insidiosum-keratitis
#18
Bhupesh Bagga, Savitri Sharma, Sai Jeevan Madhuri Guda, Ritu Nagpal, Joveeta Joseph, Kodiganti Manjulatha, Ashik Mohamed, Prashant Garg
BACKGROUND: Pythium insidiosum is a parafungus that causes keratitis resembling fungal keratitis. This study compares outcome in a large cohort of patients with P insidiosum keratitis treated with antifungal drugs, to a pilot group treated with antibacterial antibiotics. METHODS: Between January 2014 and December 2016, 114 patients with culture positive P insidiosum keratitis were included in the study. A subset of culture isolates was tested in vitro for response to nine antibacterial antibiotics by disc diffusion and E test...
March 15, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29528002/descemet-membrane-endothelial-keratoplasty-outcomes-in-the-first-year-of-experience
#19
Dilek D Altınörs, Leyla Asena
OBJECTIVES: We aimed to report the clinical outcomes of Descemet membrane endothelial keratoplasty in our first year of experience. MATERIALS AND METHODS: Patients who underwent Descemet membrane endothelial keratoplasty at the Baskent University Faculty of Medicine, Department of Ophthalmology, between 2015 and 2016 were included in the study. Patient demographics, cause of endothelial dysfunction, best-corrected visual acuity, central corneal thickness, graft survival, follow-up duration, and intraoperative and postoperative complications were recorded...
March 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29519218/recent-advances-and-anaesthetic-considerations-in-corneal-transplantation
#20
Awy Chua, M J Chua, Pca Kam
Significant surgical advances have been made recently in corneal transplantation. Penetrating keratoplasty was the dominant method from 1905, until selective lamellar keratoplasty emerged as the preferred technique over the last 20 years. Advanced techniques such as corneal limbal stem cell transplant and keratoprosthesis are also available. The major surgical complications of corneal transplantation are extrusion of ocular content and expulsive choroidal haemorrhage. It is essential for an ophthalmic anaesthetist to have a good understanding of these new surgical procedures so as to provide optimal surgical conditions...
March 2018: Anaesthesia and Intensive Care
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