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penetrating keratoplasty

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https://www.readbyqxmd.com/read/27907157/human-bone-derived-collagen-for-the-development-of-an-artificial-corneal-endothelial-graft-in-vivo-results-in-a-rabbit-model
#1
Natalia Vázquez, Manuel Chacón, Carlos A Rodríguez-Barrientos, Jesús Merayo-Lloves, Miguel Naveiras, Begoña Baamonde, Jose F Alfonso, Iriana Zambrano-Andazol, Ana C Riestra, Álvaro Meana
Corneal keratoplasty (penetrating or lamellar) using cadaveric human tissue, is nowadays the main treatment for corneal endotelial dysfunctions. However, there is a worldwide shortage of donor corneas available for transplantation and about 53% of the world's population have no access to corneal transplantation. Generating a complete cornea by tissue engineering is still a tough goal, but an endothelial lamellar graft might be an easier task. In this study, we developed a tissue engineered corneal endothelium by culturing human corneal endothelial cells on a human purified type I collagen membrane...
2016: PloS One
https://www.readbyqxmd.com/read/27895364/a-10-year-review-of-indications-for-penetrating-keratoplasty-in-a-tertiary-care-setting-in-karachi-pakistan
#2
Tanveer Ajum Chaudhry, Salman Naveed Sadiq, Zubaida Sirang, Maheen Akhtar Syed, Mustafa Kamal, Khabir Ahmad
The retrospective study was conducted to determine the indications and outomes of penetrating keratoplasty(PKP) in a tertiary care setting in Pakistan. All eyes that had undergone PKP between January 2005 and December 2014 at the Aga Khan University Hospital, Karachi, were included.Data were collected on the indications of PKP, graft survival (graft clarity at final follow-up), andbest corrected visual acuity (BCVA).Kaplan-Meier\'s method was usedto analyse graft survival.Out of 437 eyes, 383(87%) were for visual purpose...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27891366/evaluation-of-the-central-corneal-thickness-with-anterior-segment-optical-coherence-tomogram-after-penetrating-keratoplasty
#3
Anuradha Raj, Renu Dhasmana, Harsh Bahadur, Ramesh Chander Nagpal
INTRODUCTION: Graft central thickness evaluates the graft quality which affects the outcome of Penetrating Keratoplasty (PK). It varies at different point of time after PK. Anterior Segment Optical Coherence Tomography (ASOCT) can measure graft's central thickness with quite high precision. AIM: The purpose of the study was to monitor the Central Corneal thickness (CCT) with ASOCT after PK and to evaluate its relationship with the pre-operative diagnosis. MATERIALS AND METHODS: This is an observational retrospective study where records of optical PK done in December 2012 and June 2015 were reviewed...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27885526/twelve-year-follow-up-of-penetrating-keratoplasty
#4
Takashi Ono, Sosuke Ishiyama, Takeshi Hayashidera, Yosai Mori, Ryohei Nejima, Kazunori Miyata, Shiro Amano
PURPOSE: To evaluate the long-term outcomes of penetrating keratoplasty (PKP) according to the corneal disease diagnosis and the number of PKP procedures performed. METHODS: Five-hundred-and-nine eyes from 403 patients who underwent PKP at Miyata Eye Hospital in Japan from 1998 through 2014, were included in this study. Medical charts were retrospectively examined to ascertain the corneal disease diagnosis and the period of graft survival. Graft survival rates were compared among various corneal disease diagnoses and among the number of PKP procedures performed...
November 24, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27882109/excisional-keratectomy-combined-with-focal-cryotherapy-and-amniotic-membrane-inlay-for-recalcitrant-filamentary-fungal-keratitis-a-retrospective-comparative-clinical-data-analysis
#5
Yingxin Chen, Minghong Gao, Joshua K Duncan, Di Ran, Denise J Roe, Michael W Belin, Mingwu Wang
The aim of the present study was to investigate the efficacy of a novel surgical intervention, excisional keratectomy combined with focal cryotherapy and amniotic membrane inlay (EKCAI), for the treatment of recalcitrant filamentary fungal keratitis. A retrospective analysis was performed of patients who underwent excisional keratectomy combined with conjunctival flap inlay (EKCFI), EKCAI or therapeutic penetrating keratoplasty (TPK) from January 2006 to January 2011. Recalcitrance was determined as being unresponsive to standard medical antifungal therapy for at ≥1 week...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27873061/-opacification-of-a-hydrophilic-acrylic-intraocular-lens-after-dmek-a-material-analysis
#6
C Milojcic, C Latz, T Tandogan, G U Auffarth, F G Holz, C Y Choi, R Khoramnia
OBJECTIVE: Calcification of a hydrophilic intraocular lens (IOL) is a rare complication. We report on the analysis of an opacified IOL, which was explanted 2 years after Descemet membrane endothelial keratoplasty (DMEK), using light and scanning electron microscopy, X‑ray spectroscopy and investigations on the optical bench. METHODS: In October 2012 a patient with pseudophakic keratopathy and Fuchs endothelial dystrophy underwent DMEK with double rebubbling. Due to primary graft failure the patient underwent penetrating keratoplasty in January 2013...
November 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27861311/effect-of-trabeculotomy-on-corneal-endothelial-cell-loss-in-cases-of-postpenetrating-keratoplasty-glaucoma
#7
Ayaka Kusakabe, Naoki Okumura, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Noriko Koizumi, Chie Sotozono, Shigeru Kinoshita, Kazuhiko Mori
PURPOSE: The aim of this study was to evaluate the effect of trabeculotomy (TLO) on glaucoma and endothelial cell loss after penetrating keratoplasty (PK). METHODS: A retrospective study was conducted on consecutive patients who underwent PK and in whom more than 24 months of follow-up was available. Patients were categorized into the PK+TLO group [ie, TLO for post-PK glaucoma (n = 10)] and the PK group [PK alone (n = 73)]. Intraocular pressure (IOP) was evaluated during each follow-up examination...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27861304/trends-in-corneal-transplantation-in-keratoconus
#8
Daniel Sarezky, Stephen E Orlin, Wei Pan, Brian L VanderBeek
PURPOSE: To determine recent trends in and sociodemographic/comorbid conditions associated with penetrating keratoplasty (PK) and lamellar keratoplasty (LK) for keratoconus (KCN). METHODS: Patients with KCN and subsequent PK and LK procedures were identified using International Classification of Diseases, 9th revision (ICD-9) and Current Procedural Terminology (CPT) billing codes. The change in surgical rates was calculated over a decade, and multivariate analysis demonstrated factors associated with undergoing surgery...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27849319/traumatic-wound-dehiscence-after-penetrating-keratoplasty
#9
Özlem Barut Selver, Melis Palamar, Sait Eğrilmez, Ayşe Yağcı
BACKGROUND: The aim of this study was to evaluate risks and consequences of traumatic wound dehiscence after penetrating keratoplasty (PK). METHODS: Data regarding 34 eyes of 34 patients who were treated for traumatic wound dehiscence after PK between 1995 and 2014 were studied. Patient records were reviewed for type and time of insult, corrected distance visual acuity (CDVA), clinical presentation signs, operative method, and outcome. RESULTS: The interval between PK and trauma ranged from 1 month to 100 months, with median of 14 months...
September 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/27843433/successful-treatment-of-lasiodiplodia-theobromae-keratitis-assessing-the-role-of-voriconazole
#10
Stephen Tak-Lun Li, Evan Po-Fat Yiu, Angela Hiu-Yan Wong, John Chun-Ting Yeung, Lester Wang-Hon Yu
PURPOSE: The aim of this paper is to report the successful management of the first case of Lasiodiplodia theobromae keratitis in Hong Kong. METHODS: We conducted a case report. RESULTS: A 43-year-old Chinese male with a history of diabetes developed left eye keratitis after a trauma during tree felling. Fungal keratitis was diagnosed using a confocal microscope on day 1, and L. theobromae was confirmed from the culture. He was given oral voriconazole, topical natamycin, and topical and intracameral amphotericin B...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27843086/measurement-of-visual-function-among-patients-undergoing-corneal-transplantation-using-the-vf-14-index-in-morocco
#11
S Belghmaidi, L Adarmouch, M Baali, M Sebbani, I Hajji, M Amine, A Moutaouakil
OBJECTIVE: To validate the Moroccan version of the VF-14 in candidates for keratoplasty and to assess their quality of life using this tool before and after transplantation. METHODS: This is a longitudinal prospective study that assessed 57 patients who underwent penetrating keratoplasty, recruited in the ophthalmology service in Marrakech over 5 years. The original VF-14 questionnaire was adapted into Moroccan dialect. The questionnaire was administered before and 2 years after transplantation...
November 11, 2016: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/27821104/publication-trends-in-corneal-transplantation-a-bibliometric-analysis
#12
Evre Pekel, Gökhan Pekel
BACKGROUND: Our aim was to demonstrate the publication trends of corneal transplantation in the last decade. METHODS: All of the keratoplasty research articles, letters, case reports, reviews and meeting abstracts published between January 2006 and December 2015 indexed on the Thomson Reuters Web of Knowledge were evaluated. A bibliometric filter was used to capture keratoplasty related publications by using the key words 'keratoplasty', 'corneal transplantation' or 'keratoprosthesis' in the 'title' selection mode...
November 8, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27820748/triple-procedure-cataract-extraction-intraocular-lens-implantation-and-corneal-graft
#13
Yoshinori Oie, Kohji Nishida
PURPOSE OF REVIEW: Corneal triple procedures consist of combined keratoplasty surgery and cataract surgery. Currently, anterior lamellar keratoplasty, endothelial keratoplasty, and conventional penetrating keratoplasty, are very often simultaneously performed with cataract surgery. The present article reviews the recent advances and current developments in corneal triple procedures. RECENT FINDINGS: Many new findings have been reported. Core vitrectomy before host trephination and retroillumination during continuous curvilinear capsulorhexis has enabled us to perform penetrating keratoplasty triple procedures more safely...
January 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27819784/-prognostic-category-of-corneal-transplantation-in-a-referal-center
#14
Karla Verdiguel-Sotelo, Arturo Carrasco-Quiroz, Josué Rangel-Servín
BACKGROUND: Penetrating keratoplasty is considered the most frequent and successfully performed organ transplantation. Indications of corneal transplantation have changed over time and they vary according to the country. Some risk factors for graft rejection, as age, corneal vascularization or ocular surgery, among others, have been identified. The aim was to identify the prognostic category, group and associated risk factors of patients registered in the database of corneal transplantation in the Centro Médico Nacional La Raza between 2011 and 2013...
November 2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27811569/outcomes-of-penetrating-keratoplasty-with-imported-corneas-compared-with-local-corneas
#15
Parul Chawla Gupta, Jagat Ram
No abstract text is available yet for this article.
January 2017: Cornea
https://www.readbyqxmd.com/read/27811566/femtosecond-laser-assisted-anterior-lamellar-keratoplasty-for-recurrence-of-granular-corneal-dystrophy-in-postkeratoplasty-eyes
#16
Mukesh Taneja, Varsha M Rathi, Somasheila I Murthy, Bhupesh Bagga, Pravin Krishna Vaddavalli
PURPOSE: To report the clinical and visual outcome of sutureless femtosecond laser-assisted anterior lamellar keratoplasty (FALK) for recurrent granular corneal dystrophy (GCD) in patients who had previously undergone penetrating keratoplasty and phototherapeutic keratectomy (PTK) performed for recurrent dystrophy in the grafted eyes. METHODS: Four eyes of 4 patients who underwent FALK for recurrence of GCD in previously grafted eyes and underwent PTK performed for initial recurrence in the grafts were included...
November 2, 2016: Cornea
https://www.readbyqxmd.com/read/27805532/visual-rehabilitation-after-penetrating-keratoplasty
#17
Leyla Asena, Dilek D Altınörs
OBJECTIVES: Here, our aim was to report our treatment strategies and their results performed for visual rehabilitation after penetrating keratoplasty. MATERIALS AND METHODS: The medical records of 98 patients (54 male/44 female), with results from 104 eyes, who underwent penetrating keratoplasty between January 2013 and January 2015 at the Baskent University Faculty of Medicine, Department of Ophthalmology were reviewed. Patient age, indication for penetrating keratoplasty, interventions performed for visual rehabilitation, follow-up duration, topographic and refractive astigmatism at the end of follow-up, and final best corrected visual acuity results were recorded...
November 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27802912/systematic-review-comparing-penetrating-keratoplasty-and-deep-anterior-lamellar-keratoplasty-for-management-of-keratoconus
#18
REVIEW
Christin Henein, Mayank A Nanavaty
AIM: Perception of reduced incidence of graft rejection after deep anterior lamellar keratoplasty (DALK) has attracted many surgeons towards this technique in keratoconus. This review aims to compare the visual, refractive and graft outcomes after penetrating keratoplasty (PK) and DALK for keratoconus. METHODS: Electronic searches of PubMed, MEDLINE, EMBASE, Latin American and Caribbean Health Sciences Literature database (LILACS), metaRegister of Controlled Trials (mRCT), ClinicalTrial...
October 29, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27793603/corneal-toxicity-associated-with-aquarium-coral-palytoxin
#19
Asim V Farooq, Allister G Gibbons, Matthew D Council, George J Harocopos, Simon Holland, Jeffrey Judelson, Bradley L Shoss, Eric J Schmidt, Umi Kalthum Md Noh, Alexander D'Angelo, Rao V Chundury, Richard Judelson, Victor L Perez, Andrew J W Huang
PURPOSE: To report a series of patients who developed corneal toxicity after exposure to aquarium coral palytoxin. DESIGN: Multi-center retrospective case series. METHODS: Retrospective review. RESULTS: Seven patients presented with corneal findings ranging from superficial punctate epitheliopathy to bilateral corneal melt with subsequent perforation. Among those with mild corneal findings, resolution was achieved with topical steroids and lubrication, whereas some patients who developed progressive corneal melt required therapeutic penetrating keratoplasty...
October 25, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27787540/effect-of-oral-voriconazole-on-fungal-keratitis-in-the-mycotic-ulcer-treatment-trial-ii-mutt-ii-a-randomized-clinical-trial
#20
N Venkatesh Prajna, Tiruvengada Krishnan, Revathi Rajaraman, Sushila Patel, Muthiah Srinivasan, Manoranjan Das, Kathryn J Ray, Kieran S O'Brien, Catherine E Oldenburg, Stephen D McLeod, Michael E Zegans, Travis C Porco, Nisha R Acharya, Thomas M Lietman, Jennifer Rose-Nussbaumer
Objective: To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. Design, Setting, and Participants: The Mycotic Ulcer Treatment Trial II (MUTT II), a multicenter, double-masked, placebo-controlled, randomized clinical trial, was conducted in India and Nepal, with 2133 individuals screened for inclusion. Patients with smear-positive filamentous fungal ulcers and visual acuity of 20/400 (logMAR 1...
October 27, 2016: JAMA Ophthalmology
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