keyword
MENU ▼
Read by QxMD icon Read
search

penetrating keratoplasty

keyword
https://www.readbyqxmd.com/read/29931227/differential-survival-of-penetrating-and-lamellar-transplants-in-management-of-failed-corneal-grafts
#1
Jonathan Aboshiha, Mark N A Jones, Cathy L Hopkinson, Daniel F P Larkin
Importance: An increasing proportion of corneal transplant procedures are undertaken for replacement of a failed previous graft. The proportion of lamellar transplant procedures has significantly increased. There are limited large-scale reports on regraft procedures that may help guide surgeons and patients in their choice of surgery. Objective: To examine the corneal transplant replacement survival rates for the 3 main indications and types of regraft surgery. Design, Setting, and Participants: This national transplant registry study examined surgery and follow-up data on all corneal transplants performed in the United Kingdom from April 1, 1999, through March 31, 2016...
June 21, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29921952/descemet-s-membrane-endothelial-keratoplasty-surgical-outcomes-and-endothelial-cell-count-modelling-from-a-uk-centre
#2
Mark A P Fajgenbaum, Nick Kopsachilis, Emma J Hollick
PURPOSE: To report surgical outcomes and endothelial cell density (ECD) trends up to 2 years post-operatively in the first cohort of eyes undergoing Descemet's membrane endothelial keratoplasty (DMEK) for low-to-moderate risk indications at our UK centre. Tight corneal sutures were used to ensure high intraoperative pressure from intracameral air for 10-min and to maintain a good post-operative air fill. Outcomes were compared to a prior series at our unit of similar eyes having Descemet's stripping endothelial keratoplasty (DSEK)...
June 19, 2018: Eye
https://www.readbyqxmd.com/read/29916124/ocular-changes-in-nephropathic-cystinosis-the-course-of-the-gold-dust
#3
Elias Flockerzi, Loay Daas, Ursula Schlötzer-Schrehardt, Annette Zimpfer, Rainer Bohle, Berthold Seitz
PURPOSE: Cystinosis is an autosomal recessive inherited lysosomal storage disease with an incidence of 1:100.000 up to 1:200.000 caused by a gene mutation of a lysosomal transport protein resulting in deposition of cystine in lysosomes in all cells and tissues. In the cornea, crystalline, gold-dust deposition of cystine leads to visual impairment, recurrent erosions, photophobia, epiphora and blepharospasmus. Standard therapy is topical and systemic application of cysteamine which may resolve the accumulated cystine crystals...
June 18, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29912039/etiology-of-global-corneal-blindness-and-current-practices-of-corneal-transplantation-a-focused-review
#4
Priya M Mathews, Kristina Lindsley, Anthony J Aldave, Esen K Akpek
PURPOSE: The purpose of this focused review was to explore the etiologies of corneal blindness worldwide and compare them with the indications and type of keratoplasties (eg, full-thickness penetrating keratoplasty, anterior lamellar keratoplasty, or endothelial keratoplasty) performed. METHODS: A literature search of the articles published in the top 10 journals (based on the Altmetrics score) relevant to corneal transplantation within the past 20 years was performed to determine how the focus within corneal transplantation has changed over time...
June 14, 2018: Cornea
https://www.readbyqxmd.com/read/29895084/-intraoperative-optical-coherence-tomography-mi-oct-for-the-treatment-of-corneal-dystrophies
#5
Sebastian Siebelmann, Mario Matthaei, Ludwig M Heindl, Björn O Bachmann, Claus Cursiefen
BACKGROUND: The surgical treatment of corneal dystrophies develops rapidly as the use of lamellar corneal grafting techniques continue. While penetrating keratoplasty was the gold standard for treating a variety of dystrophies a few years ago, the affected layers of the cornea can, nowadays, be selectively replaced or ablated using laser technology. Of particular importance for these methods is optical coherence tomography, which has recently been integrated into surgical microscopes (MI-OCT)...
June 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29892141/delayed-complications-and-long-term-management-of-sulfur-mustard-poisoning-a-narrative-review-of-recent-advances-by-iranian-researchers-part-%C3%B0-%C3%B0-clinical-management-and-therapy
#6
REVIEW
Leila Etemad, Mohammad Moshiri, Mahdi Balali-Mood
The present study aimed to review and discuss the recommended and recently suggested protocols by Iranian researchers for a long-term treatment of delayed complications of sulfur mustard (DCSM) in veterans. As indicated clinically, patients who suffer from delayed ocular complications of sulfur mustard (DOCS) benefit from treatments for dry eyes, therapeutic contact lenses, amniotic membrane transplantation; blepharorrhaphy, tarsorrhaphy, limbal stem cell transplantation; corneal transplantation, topical steroids, and immunosuppressive...
May 2018: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29889891/aniridia-related-keratopathy-structural-changes-in-na%C3%A3-ve-and-transplanted-corneal-buttons
#7
André Vicente, Berit Byström, Mona Lindström, Ulf Stenevi, Fátima Pedrosa Domellöf
BACKGROUND: To study structural changes in naïve and surgically treated corneas of aniridia patients with advanced aniridia-related keratopathy (ARK). METHODS AND FINDINGS: Two naïve corneal buttons from patients with advanced ARK submitted to penetrating keratoplasty for the first time, one corneal button from an ARK patient that had undergone a keratolimbal allograft (KLAL), two corneal buttons from ARK patients who had previously undergone centered or decentered transplantation and were now retransplanted and two adult healthy donor control corneas were processed for immunohistochemistry...
2018: PloS One
https://www.readbyqxmd.com/read/29885816/a-report-of-10-patients-with-acanthamoeba-keratitis
#8
E A Alfonso-Muñoz, M J Roig-Revert, E Fernández-López, M Hernández-Díaz, R Araujo-Miranda, C Peris-Martínez
CLINICAL CASES: Cases are presented of 10 patients with Acanthamoeba keratitis treated between 2008 and 2017. All were contact lens wearers. All of them received treatment with a biguanide combined with a diamidine. In 3 cases the infestation did not exceed the superficial stroma, responding to topical treatment. In 7, the infection reached the deep stroma, with 6 of these cases requiring penetrating keratoplasty (PKP), 3 of them therapeutic PKP because of perforation risk or ocular spreading...
June 6, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29884145/visual-outcomes-and-prognostic-factors-in-open-globe-injuries
#9
Azusa Fujikawa, Yasser Helmy Mohamed, Hirofumi Kinoshita, Makiko Matsumoto, Masafumi Uematsu, Eiko Tsuiki, Kiyoshi Suzuma, Takashi Kitaoka
BACKGROUND: Ocular trauma is an important cause of visual loss worldwide. Improvements in our knowledge of the pathophysiology and management of ocular trauma during the past 30 years, in conjunction with advances in the instrumentation and techniques of ocular surgery, have improved the efficacy of vitreoretinal surgery in injured eyes. The aim of the current study was to determine the visual outcomes and prognostic factors of open-globe injuries in the Japanese population. METHODS: Retrospective study of 59 eyes of 59 patients presented with open globe injuries between September 2008 and March 2014 at Nagasaki University Hospital was conducted...
June 8, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29850220/total-penetrating-keratoplasty-indications-therapeutic-approach-and-long-term-follow-up
#10
Katarzyna Krysik, Ewa Wroblewska-Czajka, Anita Lyssek-Boron, Edward A Wylegala, Dariusz Dobrowolski
Purpose: Evaluation of the indications, anatomical and functional results, and complications of total penetrating keratoplasty (TPK) in disorders involving whole cornea. Materials and Methods: We analyzed outcomes of the surgical treatment of 47 eyes of 46 patients that underwent TPK. Indications were infectious keratitis, autoimmune disease, injury of the eyeball (mainly chemical burns), and other combined disorders. The surgical technique involved dissection of affected tissues with a margin of 1...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29804935/corneal-oedema-in-a-unilateral-corneal-graft-patient-induced-by-high-dk-mini-scleral-contact-lens
#11
Natalie C Guillon, Andrew Godfrey, David S Hammond
INTRODUCTION: Scleral contact lenses are increasingly becoming accepted as the method of choice for visual correction of the irregular cornea. As such, cases have surfaced which demonstrate complications arising from mini-scleral lenses. Identification of these issues and adjusting fitting techniques accordingly is necessary for reducing the risks associated with mini-scleral lens wear. CASE REPORT: A 58 year old Caucasian female was referred for rigid gas permeable contact lens fitting for correction of right irregular astigmatism post penetrating keratoplasty...
May 24, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29785085/-wet-transepithelial-phototherapeutic-keratectomy-in-the-management-of-persistent-epithelial-defects-in-the-graft
#12
Sergei V Churashov, Elena V Kudryashova, Alexei N Kulikov, Ernest V Boiko, Valerii F Chernysh, Dmitrii S Maltsev
Purpose: This study aimed to evaluate the efficacy of "wet" transepithelial phototherapeutic keratectomy (TE-PTK) for treating persistent epithelial defects (PEDs) in the corneal graft following penetrating keratoplasty (PKP). Methods: This study describes a noncomparative, prospective interventional case series. Patients with post-PKP graft epithelial defects lasting >3 months despite previous treatments with extensive wear soft contact lenses, amniotic membrane transplantation, and tarsorrhaphy were treated with wet TE-PTK...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29781928/interface-fungal-keratitis-after-descemet-stripping-automated-endothelial-keratoplasty-a-review-of-the-literature-with-a-focus-on-outcomes
#13
Elizabeth McElnea, Billy Power, Conor Murphy
PURPOSE: To examine the management and associated outcomes of reported cases of interface fungal infection after Descemet stripping automated endothelial keratoplasty (EK). METHODS: A literature review identified reports of interface fungal infection after Descemet stripping automated EK. Data retrieved from the same included patient demographics, surgical procedure undertaken, donor rim culture result, clinical course, and outcome. A review of the relevant literature was also conducted...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29766356/endothelial-cell-loss-and-graft-survival-after-penetrating-keratoplasty-for-laser-iridotomy-induced-bullous-keratopathy
#14
Naoki Okumura, Ayaka Kusakabe, Noriko Koizumi, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
PURPOSE: To assess corneal endothelial cell loss after penetrating keratoplasty (PK) treatment for laser iridotomy (LI)-induced bullous keratopathy (BK). METHODS: A retrospective study conducted on consecutive patients who underwent PK between March 2000 and December 2011. Patients who had undergone more than 24 months of follow-up were included. Patients who underwent PK were subcategorized into two groups based on their diagnosis of BK prior to PK; PK was performed to treat either LI-BK or non LI-BK...
May 15, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29763611/risk-of-glaucoma-surgery-after-corneal-transplant-surgery-in-medicare-patients
#15
Chengjie Zheng, Fei Yu, Victoria L Tseng, Flora Lum, Anne L Coleman
PURPOSE: Glaucoma is a well-documented complication of corneal transplants, contributing significantly to ultimate visual loss. Reported incidence of glaucoma following corneal transplants is highly variable, and definitions of post-transplant glaucoma are inconsistent. Here we use glaucoma surgery as a more rigid and specific endpoint to compare rates following different corneal transplant surgeries. DESIGN: Retrospective cohort study METHODS: A 5% random sample of Medicare beneficiaries from 2010-2013 was obtained and patients were identified with Current Procedural Terminology (CPT) codes for penetrating keratoplasty (PK), endothelial keratoplasty (EK), anterior lamellar keratoplasty (ALK), and keratoprosthesis (KPro)...
May 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29758184/therapeutic-penetrating-keratoplasty-button-cultures-in-the-mycotic-ulcer-treatment-trial-ii-a-randomized-trial-comparing-oral-voriconazole-vs-placebo
#16
Julie Cho, N Venkatesh Prajna, Prajna Lalitha, Revathi Rajaraman, Tiruvengada Krishnan, Yijie Brittany Lin, Kathryn J Ray, Thomas M Lietman, Jennifer Rose-Nussbaumer
OBJECTIVE: To compare oral voriconazole versus placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. DESIGN: Non-prespecified, secondary case-control analysis from a multicenter, double-masked, randomized placebo-controlled clinical trial STUDY PARTICIPANTS: Patients with smear-positive filamentous fungal ulcers and visual acuity of 20/400 or worse who eventuated to therapeutic penetrating keratoplasty (TPK). INTERVENTION: Study participants were randomized to oral voriconazole versus oral placebo; all received topical antifungal drops...
May 11, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29757853/multiplex-polymerase-chain-reaction-assay-for-screening-of-mycotoxin-genes-from-ocular-isolates-of-fusarium-species
#17
Orapin Anutarapongpan, Jorge Maestre-Mesa, Eduardo C Alfonso, Terrence P OʼBrien, Darlene Miller
PURPOSE: To identify mycotoxin genes among clinical ocular isolates of Fusarium species and to correlate these with clinical outcomes of Fusarium keratitis. METHODS: Fifty-four clinical isolates of Fusarium were retrieved from the Bascom Palmer Eye Institute Ocular Microbiology Laboratory data bank. Multiplex polymerase chain reactions were run to confirm the identification of Fusarium species [internal transcribed spacer sequence, translation elongation factor 1-α (TEF) and β-tubulin] and to detect the presence of genes encoding production of fumonisin B mycotoxins (FUM1 and FUM8) and trichothecene mycotoxins (deoxynivalenol and nivalenol)...
May 1, 2018: Cornea
https://www.readbyqxmd.com/read/29746329/descemet-membrane-endothelial-keratoplasty-after-penetrating-keratoplasty-features-for-success
#18
Adi Einan-Lifshitz, Avner Belkin, Nir Sorkin, Zale Mednick, Tanguy Boutin, Ishrat Gill, Mohammad Karimi, Clara C Chan, David S Rootman
PURPOSE: To evaluate Descemet membrane endothelial keratoplasty (DMEK) in the setting of failed penetrating keratoplasty (PKP) and to identify factors associated with DMEK success and failure after PKP. METHODS: A retrospective chart review of patients who underwent DMEK for failed PKP at Toronto Western Hospital, Canada, between 2014 and 2017 was performed. Demographic characteristics, number of previous transplants, intraoperative and postoperative complications, best spectacle-corrected visual acuity (BSCVA), and endothelial cell density were analyzed...
May 8, 2018: Cornea
https://www.readbyqxmd.com/read/29746327/pediatric-corneal-transplants-review-of-current-practice-patterns
#19
Angela Y Zhu, Maria Carolina Marquezan, Courtney L Kraus, Christina R Prescott
PURPOSE: To facilitate development of standardized guidelines for management of pediatric patients undergoing keratoplasty, particularly the youngest cohort, through a comprehensive survey assessing recent trends in practice patterns of corneal specialists and pediatric ophthalmologists. METHODS: A cross-sectional, observational study of current practices pertaining to pediatric keratoplasty was performed by designing a 20-question survey focused on preoperative indications, surgical techniques, and postoperative management...
May 8, 2018: Cornea
https://www.readbyqxmd.com/read/29734357/cyclosporine-a-drug-delivery-system-for-high-risk-penetrating-keratoplasty-stabilizing-the-intraocular-immune-microenvironment
#20
Ting Zhang, Zhiyuan Li, Ting Liu, Suxia Li, Hua Gao, Chao Wei, Weiyun Shi
Cyclosporine A (CsA) is an essential medication used to prevent corneal allograft rejection. Our preliminary studies revealed that CsA drug-delivery system (DDS) was more effective in preventing high-risk corneal allograft rejection than topical CsA application. However, the impacts of CsA DDS on the intraocular immune microenvironment were not fully elucidated. In the present study, we investigated the effect of CsA DDS on the cornea allograft, aqueous humor, and iris-ciliary body using a rabbit model of high-risk penetrating keratoplasty...
2018: PloS One
keyword
keyword
32324
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"