Melchior Linea, Hirschmann Astrid, Hofman Paul, Bontoux Christophe, Concha Angel, Mrabet-Dahbi Salima, Vannuffel Pascal, Watkin Emmanuel, Putzová Martina, Scarpino Stefania, Cayre Anne, Martin Paloma, Stoehr Robert, Hartmann Arndt
The current study assessed the performance of the fully automated RT-PCR-based Idylla™ GeneFusion Assay, which simultaneously covers the advanced non-small cell lung carcinoma (aNSCLC) actionable ALK, ROS1, RET, and MET exon 14 rearrangements, in a routine clinical setting involving 12 European clinical centers. The Idylla™ GeneFusion Assay detects fusions using fusion-specific as well as expression imbalance detection, the latter enabling detection of uncommon fusions not covered by fusion-specific assays...
March 16, 2024: Virchows Archiv: An International Journal of Pathology