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https://www.readbyqxmd.com/read/29458217/a-new-two-dimensional-shear-wave-elastography-for-noninvasive-assessment-of-liver-fibrosis-in-healthy-subjects-and-in-patients-with-chronic-liver-disease
#1
Carla Serra, Valentina Grasso, Fabio Conti, Cristina Felicani, Elena Mazzotta, Marco Lenzi, Gabriella Verucchi, Antonietta D'errico, Pietro Andreone
PURPOSE: To assess the performance of two-dimensional shear wave elastography (2D-SWE) on the GE LOGIQ E9 ultrasound system in a cohort of healthy subjects and to investigate its accuracy in the staging of liver fibrosis in patients with chronic liver disease (CLD) using liver biopsy as a reference standard. MATERIALS AND METHODS: From October 2014 to June 2016, 54 healthy subjects and 174 patients with CLD were consecutively enrolled. Liver fibrosis stage was assessed by the METAVIR scoring system...
February 19, 2018: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29458002/the-effect-of-time-of-day-testing-and-utility-of-30-and-60-minute-cortisol-values-in-the-250-mcg-acth-stimulation-test
#2
Vicki Munro, Manal Elnenaei, Steve Doucette, David B Clarke, Syed Ali Imran
BACKGROUND: Despite widespread use of the 250-mcg Cosyntropin test (ACTH test) for the diagnosis of adrenal insufficiency (AI), the effect of time of day and the utility of performing both 30- and 60-min serum cortisol values remains unclear. METHODS: We conducted a retrospective cohort study of all ACTH testing at the Halifax Neuropituitary Program, Nova Scotia, Canada between January 2006 and April 2016. Data were collected on age, gender, medication history, serum cortisol levels at 0, 30 and 60 min after ACTH administration, as well as time of and indication for testing...
February 16, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29457471/beck-depression-inventory-as-a-screening-tool-for-depression-in-chronic-haemodialysis-patients
#3
A Bautovich, I Katz, C K Loo, S B Harvey
OBJECTIVES: To evaluate the psychometric properties of the Beck Depression Inventory (BDI) and Cognitive Depression Index (CDI) as a potential screening tool for major depression in haemodialysis (HD) patients. METHODS: Forty-five HD patients completed both the BDI/CDI and diagnostic interview. The interview was conducted by two experienced clinicians and was based on DSM-IV criteria. The sensitivity, specificity and positive (PPV) and negative (NPV) predictive values were then calculated...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29457436/-clinical-application-of-tibial-composite-saphenous-nervetissue-flap-for-the-treatment-of-traumatic-bone-skin-defect-of-leg
#4
Zhi-Wei Zhao, Wen-Jing Liu, Zhu-Qing Zha, Yan-Feng Li, Hui-Jun Fan
OBJECTIVE: To investigate the effect of tibial composite saphenous nerve tissue flap in repairing traumatic bone-skin defect of leg. METHODS: From February 2009 to May 2015, 23 patients with focile skin defect caused by trauma were treated, including 18 males and 5 females, aged from 8 to 59 years old with an average age of 35.6 years old. Length of tibia bone cortex defect ranged from 4 to 12 cm, width ranged from 2 to 2.5cm, skin defect ranged from 8 cm× 3 cm to 18 cm× 11 cm, all the wound surfaces had purulent exudation...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457355/visceral-obesity-is-a-significant-risk-factor-for-incisional-hernia-after-laparoscopic-colorectal-surgery-a-single-center-review
#5
Masateru Yamamoto, Yuji Takakura, Satoshi Ikeda, Toshiyuki Itamoto, Takashi Urushihara, Hiroyuki Egi
INTRODUCTION: Although laparoscopic surgery uses relatively small incisions, incisional hernia after surgery is not uncommon. However, the incidence of incisional hernia and its risk factors are not well known. The purpose of our study was to investigate risk factors for incisional hernia after laparoscopic colorectal cancer surgery. METHODS: The study group consisted of 212 patients who underwent laparoscopic colorectal cancer surgery at Hiroshima Prefectural Hospital between November 2008 and October 2013...
February 19, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29457156/effect-of-calcium-hydroxide-on-bonding-performance-of-an-experimental-self-etch-adhesive
#6
Marcelle Gonçalves Garcia, Laiza Tatiana Poskus, Viviane Hass, Cristiane Mariote Amaral, Jaime Dutra Noronha-Filho, Eduardo Moreira da Silva
PURPOSE: To investigate the effect of Ca(OH)2 concentration on pH neutralization, degree of conversion (DC%), and bonding performance of experimental self-etch adhesives (SEAs). MATERIALS AND METHODS: Four different concentrations of Ca(OH)2 (0 wt%, 1 wt%, 2 wt%, and 4 wt%) were added to the bond of an experimental two-step SEA consisting of primer (10-MDP [30 wt%], TEG-DMA [30 wt%], ethanol [35 wt%], water [5 wt%], camphorquinone [0.5 wt%], and tertiary amine [0...
February 16, 2018: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/29456950/cerebrospinal-fluid-leakage-during-temporal-bone-surgery-selecting-intra-operative-dural-closure-with-a-dumbbell-shaped-muscle-graft-as-a-surgical-approach
#7
Nasrin Yazdani, Mohammad Taghi Khorsandi-Ashtiani, Hamed Tashakorinia, Mahtab Rabbani Anari, Narges Mikaniki
Cerebrospinal fluid (CSF) leakages of the temporal bone may arise during mastoid surgery. The leakages can have multiple potential etiologies, for instance, using a cutting burr near the bony tegmen or monopolar electrocautery on the surface of the dura mater. In this paper, we introduced an effective and simple technique for the management of CSF leakages of the temporal bone. In a prospective case series, 36 patients (16 males and 20 females) who have had an experience of incidental or inevitable CSF otorrhea or otorhinorrhea during temporal bone surgery were selected...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456934/outcomes-of-transconjuctival-sutureless-27-gauge-vitrectomy-for-stage-4-retinopathy-of-prematurity
#8
Parag K Shah, Vishma Prabhu, Venkatapathy Narendran
AIM: To report our initial experience with lens-sparing vitrectomy for stage 4 retinopathy of prematurity using the 27-gauge (G) system. METHODS: This retrospective case series involved nine eyes of five babies with active stage 4 ROP, who underwent 27-G lens-sparing vitrectomy. Surgery was done using 27-G valved cannulas and sclerotomies were made 1.5 mm from the limbus. Bilateral sequential vitrectomy was done in eight eyes. RESULTS: At one-year follow-up, anatomical outcome was favourable in all nine (100%) eyes...
February 8, 2018: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/29456896/factors-associated-with-elevated-blood-pressure-or-hypertension-in-afro-caribbean-youth-a-cross-sectional-study
#9
Trevor S Ferguson, Novie O M Younger-Coleman, Marshall K Tulloch-Reid, Nadia R Bennett, Amanda E Rousseau, Jennifer M Knight-Madden, Maureen E Samms-Vaughan, Deanna E Ashley, Rainford J Wilks
Background: Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence the risk of high BP. In this study, we estimated the relative risk for elevated BP or hypertension (EBP/HTN), defined as BP ≥ 120/80 mmHg, among young adults with putative cardiovascular disease (CVD) risk factors in Jamaica and evaluated whether relative risks differed by sex...
2018: PeerJ
https://www.readbyqxmd.com/read/29456696/infectious-mononucleosis-and-hepatic-function
#10
Li Zhang, Pingping Zhou, Zhaowei Meng, Chongjie Pang, Lu Gong, Qing Zhang, Qiyu Jia, Kun Song
Abnormal hepatic function is common in infectious mononucleosis (IM). However, it remains unknown why increased transferase levels are more common than bilirubin abnormalities in IM. The current study aimed to investigate these associations in the Chinese population. A total of 95 patients with IM (47 males and 48 females) were enrolled in the current study, as well as 95 healthy controls. Patients were sorted by sex. A receiver operating characteristic (ROC) curve was used to determine cut-off values for IM diagnosis and prediction...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456656/comparison-of-the-diagnostic-efficacy-between-ultrasound-elastography-and-magnetic-resonance-imaging-for-breast-masses
#11
Rong Cheng, Jing Li, Li Ji, Huining Liu, Limin Zhu
The present study compared the efficacy of ultrasound elastography (UE), magnetic resonance imaging (MRI) and the combination of the two methods (UE+MRI) in the differential diagnosis of benign and malignant breast tumors. In total, 86 patients with breast masses were recruited and evaluated by UE, MRI and UE+MRI. Strain ratios of UE were calculated for the breast mass and adjacent normal tissues. In addition, the receiver operating characteristic (ROC) curve was obtained, while the sensitivity and specificity were calculated to determine the optimal cut-off point for the differential diagnosis...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456578/sonographic-parameters-for-diagnosing-fetal-head-engagement-during-labour
#12
Yaw A Wiafe, Bill Whitehead, Heather Venables, Alexander T Odoi
The purpose of this study was to investigate the diagnostic performance of the head-perineum distance, angle of progression, and the head-symphysis distance as intrapartum ultrasound parameters in the determination of an engaged fetal head. Two hundred and one women in labour underwent both ultrasound and digital vaginal examination in the estimation of fetal head station. The transperineal ultrasound measured head-perineum distance, angle of progression, and head-symphysis distance for values correlating with digital vaginal examination head station...
February 2018: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29456445/concurrent-validation-of-a-pressure-pain-threshold-scale-for-individuals-with-myofascial-pain-syndrome-and-fibromyalgia
#13
Scott W Cheatham, Morey J Kolber, G Monique Mokha, William J Hanney
Background: Manual pressure palpation is an examination technique used in the classification of myofascial pain syndrome (MPS) and fibromyalgia (FM). Currently, there are no validated systems for classifying results. A valid and reliable pressure pain threshold scale (PPTS) may provide a means for clinicians to grade, document, and report findings. The purpose of this investigation was to validate a PPTS in individuals diagnosed with MPS and FM. Intra-rater reliability, concurrent validity, minimum cut-off value, and patient responses were evaluated...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29456412/performance-of-transient-elastography-in-assessing-liver-fibrosis-in-patients-with-autoimmune-hepatitis-primary-biliary-cholangitis-overlap-syndrome
#14
Hui-Min Wu, Li Sheng, Qi Wang, Han Bao, Qi Miao, Xiao Xiao, Can-Jie Guo, Hai Li, Xiong Ma, De-Kai Qiu, Jing Hua
AIM: To investigate the performance of transient elastography (TE) for diagnosis of fibrosis in patients with autoimmune hepatitis-primary biliary cholangitis (AIH-PBC) overlap syndrome. METHODS: A total of 70 patients with biopsy-proven AIH-PBC overlap syndrome were included. Spearman correlation test was used to analyze the correlation of liver stiffness measurement (LSM) and fibrosis stage. Independent samples Student's t -test or one-way analysis of variance was used to compare quantitative variables...
February 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29456411/clinical-utility-of-hepatitis-b-surface-antigen-kinetics-in-treatment-na%C3%A3-ve-chronic-hepatitis-b-patients-during-long-term-entecavir-therapy
#15
Tien-Ching Lin, Yen-Cheng Chiu, Hung-Chih Chiu, Wen-Chun Liu, Pin-Nan Cheng, Chiung-Yu Chen, Ting-Tsung Chang, I-Chin Wu
AIM: To investigate the utility of hepatitis B surface antigen (HBsAg) kinetics in chronic hepatitis B patients during long-term entecavir treatment. METHODS: This retrospective study included treatment-naïve chronic hepatitis B patients who received at least 2 years of consecutive entecavir treatment. Patients were followed up at three to six month intervals with liver biochemistry, hepatitis B virus DNA, and abdominal sonography. In hepatitis B e antigen (HBeAg)-positive patients, HBeAg levels were assessed every three to six month until results became negative...
February 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29456398/urinary-cotinine-level-in-indonesian-children-exposed-to-domestic-cigarette-smoke
#16
Agus Dwi Susanto, Priska Duana Putri, Achmad Hudoyo, Feni Fitriani Taufik, Fariz Nurwidya, Sita Andarini
Background: Cotinine is a major metabolite of nicotine, and its urinary level is an indicator of exposure to cigarette smoke. The present study was aimed at identifying the urinary cotinine level in Indonesian children who were exposed and not exposed to domestic cigarette smoke. Methods: The study was a cross-sectional study in elementary school-aged children who had not smoked. The subjects were categorized into an exposed group and unexposed group based on their exposure status...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29455687/distinct-risk-factors-for-obsessive-and-compulsive-symptoms-in-chronic-schizophrenia
#17
Emilio Fernandez-Egea, Yulia Worbe, Miguel Bernardo, Trevor W Robbins
BACKGROUND: Obsessive-compulsive disorder (OCD) is common in clozapine-treated patients although the actual prevalence, phenomenology and risk factors remain unclear. The aim of the present study was to address the three aforementioned questions. METHODS: The electronic records of a large cohort of clozapine-medicated schizophrenia patients routinely screened for OCD were used. The Obsessive Compulsive Inventory Revised version (OCI-R) was available from 118 cases and a 21 points cut-off threshold for OCD was defined...
February 19, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29455320/elevated-serum-krebs-von-den-lungen-6-in-systemic-sclerosis-a-marker-of-lung-fibrosis-and-severity-of-the-disease
#18
Audrey Benyamine, Xavier Heim, Noémie Resseguier, Daniel Bertin, Carine Gomez, Mikaël Ebbo, Jean-Robert Harlé, Gilles Kaplanski, Pascal Rossi, Nathalie Bardin, Brigitte Granel
OBJECTIVES: We aimed to assess the clinical significance of Krebs von den Lungen-6 (KL-6) in the diagnosis and severity of interstitial lung disease (ILD) in a French cohort of patients with systemic sclerosis (SSc). METHODS: Serum KL-6 concentrations were measured with chemiluminescent enzyme immunoassay (CLEIA) in 75 SSc patients. Patients were divided into two groups according to the presence of interstitial lung disease (SSc-ILD versus SSc-without ILD) on chest High-Resolution Computed Tomography...
February 17, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29455244/rotation-of-intramedullary-alignment-rods-affects-distal-femoral-cutting-plane-in-total-knee-arthroplasty
#19
Günther Maderbacher, Jan Matussek, Armin Keshmiri, Felix Greimel, Clemens Baier, Joachim Grifka, Hermann Maderbacher
PURPOSE: Intramedullary rods are widely used to align the distal femoral cut in total knee arthroplasty. We hypothesised that both coronal (varus/valgus) and sagittal (extension/flexion) cutting plane are affected by rotational changes of intramedullary femoral alignment guides. METHODS: Distal femoral cuts using intramedullary alignment rods were simulated by means of a computer-aided engineering software in 4°, 6°, 8°, 10°, and 12° of valgus in relation to the femoral anatomical axis and 4° extension, neutral, as well as 4°, 8°, and 12° of flexion in relation to the femoral mechanical axis...
February 17, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29455048/a-clinical-prediction-score-to-determine-surgical-drainage-of-deep-neck-infection-a-retrospective-case-control-study
#20
Myung Jin Ban, Jae Yeup Jung, Jae Wook Kim, Ki Nam Park, Seung Won Lee, Yoon Woo Koh, Jae Hong Park
BACKGROUND: The objective of this retrospective study was to identify predictors of an abscess guaranteed to be surgically drained successfully in patients with deep neck infection (DNI). MATERIALS AND METHODS: We divided 97 consecutive patients with DNI into a drained group and a non-drained group. We then developed a clinical prediction score and validated it in 32 further patients. RESULTS: Significant predictors of successful surgical drainage (i...
February 15, 2018: International Journal of Surgery
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