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https://www.readbyqxmd.com/read/29046043/introduction-to-the-special-issue-on-adolescent-and-young-adult-health-why-we-care-how-far-we-have-come-and-where-we-are-going
#1
Katie A Devine, Maureen Monaghan, Lisa A Schwartz
This special issue on adolescent and young adult (AYA) health comprises 15 original articles. The special issue recognizes the importance of AYA-focused research, highlights unique issues across the AYA period, and showcases cutting-edge research focused on AYAs. We describe the rationale for focusing on the AYA population, themes of the special issue, and future directions.
October 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29046003/-ffr-guided-revascularisation-pros-and-cons
#2
Hannes Reuter, Stephan Baldus
An invasive measurement of the fractional flow reserve (FFR) allows the valuation of the individual risk for ischemic events in patients with coronary artery disease. Therefore, FFR has become a valuable tool to guide coronary revascularisations. The cut-off value ≤ 0.80 has been validated in many different subsets of patients. However, FFR values describe a risk continuum with an inverse correlation between FFR value and the risk of events. So FFR should always be interpreted regarding the patient's clinical context, especially in patients with a high risk for rapid disease progression...
October 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29045971/-technical-improvement-in-retroperitoneal-laparoscopic-living-donor-nephrectomy-report-of-193-cases
#3
L Zhao, L L Ma, H X Zhang, X F Hou, L Liu, Y Fu, Y G Kou, Y M Song
OBJECTIVE: To summarize our experience of retroperitoneal laparoscopic living donor nephrectomy, our continuous technical improvements and refinement of this skill and standardization of each procedure of this operation. METHODS: Having approved by hospital ethical committee and local government administration, a total of 193 living donors underwent retroperitoneal laparoscopic living donor nephrectomy from Dec.2003 to Feb. 2016 in our department. Under general anaesthesia, the operation was performed through 3 lumbar ports...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045957/-clinical-characteristics-of-neonatal-fungal-sepsis-in-neonatal-intensive-care-unit
#4
X Zhang, X F Ru, Y Wang, X Li, T Sang, Q Feng
OBJECTIVE: To study the characteristics of neonatal fungal sepsis and the difference between bacterial sepsis and fungal sepsis. To improve the understanding of neonatal fungal sepsis. METHODS: Clinical data of neonatal fungal sepsis in neonatal intensive care unit (NICU) were collected from 2011 to 2016 in Peking University first Hospital. The clinical characteristics were analyzed retrospectively. The difference between neonatal fungal sepsis and bacterial sepsis was also analyzed...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045916/suicide-deaths-among-patients-with-end-stage-renal-disease-receiving-dialysis-a-population-based-retrospective-cohort-study-of-64-000-patients-in-taiwan
#5
I-Ming Chen, Po-Hsien Lin, Vin-Cent Wu, Chi-Shin Wu, Jia-Chi Shan, Shu-Sen Chang, Shih-Cheng Liao
BACKGROUND: Patients with end-stage renal disease (ESRD) who receive dialysis may experience increased distress and risk of suicide. METHODS: This population-based retrospective cohort study linked Taiwan's national register of ESRD patients on dialysis and the cause-of-death mortality data file. A separate multiple-cause-of-death data file was used to investigate the detailed suicide methods used. Standardized mortality ratios (SMRs) were calculated for the overall patient group and by sex, age, year of initiating dialysis, method of suicide, and time since initiation of dialysis...
October 9, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29045709/joint-effect-of-physical-activity-and-sedentary-behaviour-on-cardiovascular-risk-factors-in-chilean-adults
#6
Carlos Cristi-Montero, Lewis Steell, Fanny Petermann, Alex Garrido-Méndez, Ximena Díaz-Martínez, Carlos Salas-Bravo, Rodrigo Ramirez-Campillo, Cristian Alvarez, Fernando Rodriguez, Nicolas Aguilar-Farias, Maria A Martinez, Ana M Leiva, Felipe Poblete-Valderrama, Naomi D Willis, Carlos A Celis-Morales
Background: To investigate the associations between combined categories of moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) with markers of adiposity and cardiovascular risk in adults. Methods: Overall, 5040 participants (mean age 46.4 years and 59.3% women) from the cross-sectional Chilean National Health Survey 2009-2010 were included in this study. MVPA and SB were measured using the Global Physical Activity questionnaire. Four categories were computed using MVPA- and SB-specific cut-offs ('High-SB & Active', 'Low-SB & Active', 'High-SB & Inactive' and 'Low-SB & Inactive')...
October 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29045598/prognostic-value-of-pulmonary-blood-volume-by-first-pass-contrast-enhanced-cmr-in-heart-failure-outpatients-the-prove-hf-study
#7
F Ricci, A Barison, G Todiere, C Mantini, A R Cotroneo, M Emdin, R De Caterina, S Galllina, G D Aquaro
Aims: Pulmonary blood volume (PBV) is a novel clinical application of cardiovascular magnetic resonance (CMR) imaging for the quantitative grading of haemodynamic congestion. In this study, we aimed to assess the prognostic value of PBV in a cohort of outpatients with chronic heart failure (HF). Methods and results: One hundred and twelve consecutive patients (91 men, 67 ± 12 years) and 53 age- and sex-matched healthy controls underwent echocardiography and contrast-enhanced CMR...
October 17, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29044983/horseradish-peroxidase-catalyzed-hydrogelation-for-biomedical-biopharmaceutical-and-biofabrication-applications
#8
Shinji Sakai, Masaki Nakahata
Horseradish peroxidase (HRP)-catalyzed hydrogelation has attracted much attention due to the ease of handling, high biocompatibility, and processability. This review summarizes recent developments including cutting-edge research using HRP-mediated hydrogelation toward biomedical, biopharmaceutical, and biofabrication applications. From the viewpoint of polymer chemistry, the basic chemistry behind hydrogelation, the structure-property relationship, and hybridization of multiple materials using HRP-catalyzed hydrogelation are summarized...
October 18, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29044603/comorbid-masticatory-impairment-delays-recovery-from-acute-cerebral-ischemia-and-locomotor-hypoactivity-after-subarachnoid-hemorrhage-in-mice
#9
Ikuho Kojima, Tatsushi Mutoh, Kazumasu Sasaki, Yasuko Tatewaki, Yasuyuki Taki, Tatsuya Ishikawa
Tooth loss and related changes in the functionality may lead to worse outcome of stroke patients, but the link involved in this pathway remains unclear. This study aimed to determine the effect of comorbid masticatory impairment on acute cerebral ischemia and neurobehavioral outcome after experimental subarachnoid hemorrhage (SAH). Thirty C57BL/6 mice with (molar-less) or without (control) prior treatment of cutting off the upper molars (separated by at least one week), were subjected to SAH by endovascular perforation...
October 17, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29044327/generation-of-a-triple-fluorescent-mouse-strain-allows-a-dynamic-and-spatial-visualization-of-different-liver-phagocytes-in-vivo
#10
Brenda N Nakagaki, Maria A Freitas-Lopes, Érika Carvalho, Raquel Carvalho-Gontijo, Hortência M Castro-Oliveira, Rafael M Rezende, Denise C Cara, Mônica M Santos, Rodrigo Pestana Lopes, Bruna A David, Gustavo B Menezes
Resident and circulating immune cells have been extensively studied due to their almost ubiquitous role in cell biology. Despite their classification under the "immune cell department", it is becoming increasingly clear that these cells are involved in many different non-immune related phenomena, including fetus development, vascular formation, memory, social behavior and many other phenotypes. There is a huge potential in combining high-throughput assays - including flow cytometry and gene analysis - with in vivo imaging...
October 16, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29044295/clinical-decision-rules-for-pulmonary-embolism-in-hospitalized-patients-a-systematic-literature-review-and-meta-analysis
#11
Anne R Bass, Kara G Fields, Rie Goto, Gregory Turissini, Shirin Dey, Linda A Russell
Background Clinical decision rules (CDRs) for pulmonary embolism (PE) have been validated in outpatients, but their performance in hospitalized patients is not well characterized. Objectives The goal of this systematic literature review was to assess the performance of CDRs for PE in hospitalized patients. Methods We performed a structured literature search using Medline, EMBASE and the Cochrane library for articles published on or before January 18, 2017. Two authors reviewed all titles, abstracts and full texts...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29044193/effect-of-surface-and-internal-defects-on-the-mechanical-properties-of-metallic-glasses
#12
Sunghwan Kim, Seunghwa Ryu
Despite the significance of surface effects on the deformation behaviours of small-scale metallic glasses, systematic investigations on surface states are lacking. In this work, by employing atomistic simulations, we characterise the distributions of local inhomogeneity near surfaces created by casting and cutting, along with internal distributions in pristine and irradiated bulk specimens, and investigate the effects of inhomogeneity on the mechanical properties. The cast surface shows enhanced yield strength and degrees of shear localisation, while the cut surface shows the opposite effects, although the fraction of vibrational soft spots, known to indicate low-energy barriers for local rearrangement, is high near both surfaces...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29044163/materials-analysis-and-focused-ion-beam-nanofabrication-of-topological-insulator-bi2se3
#13
Sarah Friedensen, Jerome T Mlack, Marija Drndić
Focused ion beam milling allows manipulation of the shape and size of nanostructures to create geometries potentially useful for opto-electronics, thermoelectrics, and quantum computing. We focus on using the ion beam to control the thickness of Bi2Se3 and to create nanowires from larger structures. Changes in the material structure of Bi2Se3 nanomaterials that have been milled using a focused ion beam are presented. In order to characterize the effects of ion beam processing on the samples, we use a variety of techniques including analytical transmission electron microscopy and atomic force microscopy...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29044050/on-atomic-mechanisms-governing-the-oxidation-of-bi-sub-2-sub-te-sub-3-sub
#14
Denis Music, Keke Chang, Paul Schmidt, Felix N Braun, Martin Heller, Steffen Hermsen, Peter J Pöllmann, Till Schulzendorff, Cedric Wagner
Oxidation of Bi2Te3 (space group R-3m) has been investigated using experimental and theoretical means. Based on calorimetry, x-ray photoelectron spectroscopy and thermodynamic modelling, Bi2Te3 is at equilibrium with Bi2O3 and TeO2, whereby the most stable compound is Bi2Te3, followed by Bi2O3. Hence, the reactivity of Bi towards oxygen is expected to be higher than that of Te. This notion is supported by density functional theory. The strongest bond is formed between Bi and Te, followed by Bi - O. This gives rise to unanticipated atomic processes...
October 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29043967/dual-head-screw-hip-nailing-for-trochanteric-fractures
#15
Andreas F Mavrogenis, Vasilios G Igoumenou, Panayiotis D Megaloikonomos, George N Panagopoulos, Ioannis P Galanopoulos, Christos Th Vottis, Eirinaios Karamanis, Panayiotis Koulouvaris, Panayiotis J Papagelopoulos
INTRODUCTION: There are limited information and inconclusive results for dual head screw intramedullary hip nails for trochanteric fractures. Therefore, we performed a prospective study to evaluate the healing of fractures, and survival, function, and complications of patients operated with this implant. METHODS: We prospectively studied 79 patients (61 women and 18 men; mean age: 84.7 years; range: 65-96 years) with a low-energy trochanteric fracture, treated with a dual head screw intramedullary hip nail from 2013 to 2016...
2017: SICOT-J
https://www.readbyqxmd.com/read/29043879/use-of-an-objective-structured-clinical-exam-osce-for-early-identification-of-communication-skills-deficits-in-interns
#16
Mary Ellen J Goldhamer, Amy Cohen, Michelle Brooks, Eric A Macklin, John Patrick T Co, Debra Weinstein
INTRODUCTION: There is limited information about whether OSCE during GME orientation can identify trainee communication deficits before these become evident via clinical performance evaluations. METHODS: Ninety-seven interns matriculating to eight residency programs in six specialties at four hospitals participated in a nine-station communication skills OSCE. Ratings were based on the "Kalamazoo, adapted" communication skills checklist. Possible association with intern performance evaluations was assessed by repeated-measures logistic regression and ROC curves were generated...
October 18, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29043850/age-adjusted-d-dimer-cut-off-in-the-diagnostic-strategy-for-deep-vein-thrombosis-a-systematic-review
#17
Mads Nybo, Anne-Mette Hvas
BACKGROUND: Studies have indicated that use of an age-adjusted D-dimer cut-off value for patients above 50 years increases utility of the diagnostic strategy for pulmonary embolism. Evidence for the same approach regarding diagnosis of deep vein thrombosis (DVT) is, however, unclear. MATERIALS AND METHODS: A systematic literature review was conducted following the PRISMA Statement guideline to gather the existing knowledge on the use of an age-adjusted D-dimer cut-off in the diagnostic strategy for DVT...
October 18, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29043522/cryovial-monolayer-vitrification-for-ovarian-tissue-cryopreservation
#18
Hongxia Li, Haixia Cao, Xingping Guo, Huaixiu Wang
The cryopreservation of ovarian tissue has been proved to be effective for fertility preservation. To find a better cryopreservation method, we tested the efficacy of cryovial monolayer vitrification method in comparison with that of needle immersed vitrification (NIV). Ovaries from 10 female kunming mice aged 6-8 weeks were cut into pieces and allocated into group A (cryovial monolayer vitrification method), group B (NIV method) and group C (fresh control). In group A, pieces of ovarian tissue were layered around the inner wall of cryovial as a monolayer; and in group B, pieces of ovarian tissue were pierced with a needle...
October 17, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/29043400/static-and-dynamic-18-f-fet-pet-for-the-characterization-of-gliomas-defined-by-idh-and-1p-19q-status
#19
Antoine Verger, Gabriele Stoffels, Elena K Bauer, Philipp Lohmann, Tobias Blau, Gereon R Fink, Bernd Neumaier, Nadim J Shah, Karl-Josef Langen, Norbert Galldiks
PURPOSE: The molecular features isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion have gained major importance for both glioma typing and prognosis and have, therefore, been integrated in the World Health Organization (WHO) classification in 2016. The aim of this study was to characterize static and dynamic O-(2-(18)F-fluoroethyl)-L-tyrosine ((18)F-FET) PET parameters in gliomas with or without IDH mutation or 1p/19q co-deletion. METHODS: Ninety patients with newly diagnosed and untreated gliomas with a static and dynamic (18)F-FET PET scan prior to evaluation of tumor tissue according to the 2016 WHO classification were identified retrospectively...
October 17, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29043329/scmo-bo3-m-ca-and-cd-new-sc-based-oxyborates-featuring-interesting-edge-sharing-sandwich-like-chains-and-uv-cut-off-edges
#20
Ruru Ma, Dongdong Xu, Yun Yang, Xin Su, Binghua Lei, Zhihua Yang, Shilie Pan
Two new isostructural rare-earth oxyborates ScMO(BO3) (M = Ca and Cd) with a three-dimensional (3D) cationic framework and parallel arranged [BO3] triangles have been synthesized by the flux method. In the 3D cationic framework, an interesting sandwich-like basic building unit (BBU) is constructed by two [Ca(1)O4](6-) chains and two [Sc(1)O4](5-) chains. ScMO(BO3) melt incongruently, which shows that title compounds can be grown by the flux method. The UV cut-off edges for ScCaO(BO3) and ScCdO(BO3) are 230 and 249 nm, respectively...
October 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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