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papillomavirus and vaccine

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https://www.readbyqxmd.com/read/29141014/prevalence-and-risk-factors-of-anal-human-papillomavirus-infection-among-hiv-negative-men-who-have-sex-with-men-in-urumqi-city-of-xinjiang-uyghur-autonomous-region-china
#1
Tian Tian, Peierdun Mijiti, Huang Bingxue, Zhang Fadong, Abidan Ainiwaer, Sang Guoyao, Zhang Zhanlin, Yeledan Mahan, Tuo Xiaoqin, Gong Zheng, Dai Jianghong
BACKGROUND: Infection with human papillomavirus (HPV) is the most common sexually transmitted infection among men who have sex with men (MSM). Study on prevalence and risk factors of anal HPV infection among HIV-negative MSM in Northwestern China was rare. METHODS: We performed a cross-sectional study of HPV prevalence using anal swab specimens among HIV-negative MSM in Urumqi city of Xinjiang Uyghur Autonomous Region, China between April 1st and October 30th in 2016...
2017: PloS One
https://www.readbyqxmd.com/read/29140750/postlicensure-safety-surveillance-of-congenital-anomaly-and-miscarriage-among-pregnancies-exposed-to-quadrivalent-human-papillomavirus-vaccine
#2
Lina S Sy, Kristin I Meyer, Nicola P Klein, Chun Chao, Christine Velicer, T Craig Cheetham, Bradley K Ackerson, Jeff M Slezak, Harpreet S Takhar, John Hansen, Kamala Deosaransingh, Kai-Li Liaw, Steven J Jacobsen
Limited safety data are available on inadvertent exposure to quadrivalent human papillomavirus vaccine (4vHPV) during pregnancy. We conducted a descriptive observational postlicensure safety surveillance study in Kaiser Permanente Southern California and Northern California to assess congenital anomaly and miscarriage among pregnancies exposed to 4vHPV. Using electronic medical records, we identified women who received a dose of 4vHPV between August 2006 and March 2008 within 30 days preconception or any time during a possible pregnancy...
November 15, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29140439/bivalent-vaccine-effectiveness-against-type-specific-hpv-positivity-evidence-for-cross-protection-against-oncogenic-types-among-dutch-sti-clinic-visitors
#3
Petra J Woestenberg, Audrey J King, Birgit H B van Benthem, Robine Donken, Suzan Leussink, Fiona R M van der Klis, Hester E de Melker, Marianne A B van der Sande, Christian J P A Hoebe, Johannes A Bogaards
Background: Observational post-marketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human papillomavirus (HPV) vaccine against HPV positivity of vaccine and non-vaccine types in a high-risk population. Methods: We included all vaccine-eligible women from the PASSYON study, a biennial cross-sectional survey in Dutch sexually transmitted infection clinics. Vaginal swabs were analyzed using a PCR-based assay (SPF10-LiPA25) able to detect the 12 high-risk HPV (hrHPV) types 16/18/31/33/35/39/45/51/52/56/58/59...
November 11, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29136168/a-prospective-study-of-the-incidence-of-juvenile-onset-recurrent-respiratory-papillomatosis-after-implementation-of-a-national-hpv-vaccination-program
#4
Daniel Novakovic, Alan T L Cheng, Yvonne Zurynski, Robert Booy, Paul J Walker, Robert Berkowitz, Henley Harrison, Robert Black, Christopher Perry, Shyan Vijayasekaran, David Wabnitz, Hannah Burns, Sepehr N Tabrizi, Suzanne M Garland, Elizabeth Elliott, Julia M L Brotherton
Background: Recurrent respiratory papillomatosis is a rare but morbid disease caused by human papillomavirus (HPV) types 6 and 11. Infection is preventable through HPV vaccination. Following an extensive quadrivalent HPV vaccination program (females 12-26 years in 2007-2009) in Australia, we established a method to monitor incidence and demographics of juvenile-onset recurrent respiratory papillomatosis (JORRP) cases. Methods: The Australian Paediatric Surveillance Unit undertakes surveillance of rare pediatric diseases by contacting practitioners monthly...
November 9, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29136167/juvenile-onset-recurrent-respiratory-papillomatosis-the-benefits-of-quadrivalent-human-papillomavirus-vaccination-continue-to-accrue
#5
Basil Donovan, Denton Callander
No abstract text is available yet for this article.
November 9, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29135538/cervical-morbidity-in-alsace-france-results-from-a-regional-organized-cervical-cancer-screening-program
#6
Jean-Jacques Baldauf, Muriel Fender, Christine Bergeron, Emilie Marrer, Michel Velten, Pierre Pradat, Marc Arbyn
In 1994, a pilot program of cervical cancer screening was introduced in the Alsace region, France. Women aged 25-65 years were proposed to have one Pap smear every 3 years. The objective was to assess cervical morbidity in Alsace before the human papillomavirus vaccinated population reaches the age of screening. Data on cervical lesions and cancers were collected by EVE for the period September 2008 to August 2011 from existing medical services and cytopathology laboratories in Alsace. Cytological and histological data were completed with data from the two cancer registries covering the region (Bas-Rhin and Haut-Rhin)...
November 13, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29134823/does-self-efficacy-mediate-the-relationships-between-social-cognitive-factors-and-intentions-to-receive-hpv-vaccination-among-young-women
#7
Shannon M Christy, Joseph G Winger, Catherine E Mosher
Drawing upon health behavior change theories, the current study examined whether self-efficacy mediated relationships between social-cognitive factors (i.e., perceived risk, perceived benefits, perceived barriers, perceived severity, and cue to action) and human papillomavirus (HPV) vaccination intentions among college women. Unvaccinated women ( N = 115) aged 18 to 25 years attending a Midwestern university completed an anonymous web-based survey assessing study variables. Correlational analyses and mediation analyses were conducted...
November 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/29134256/-extragenital-disseminated-infection-with-human-papillomaviruses-therapeutic-response-through-vaccination-with-hpv
#8
L Wiskemann, B Durani, W Hartschuh
A 50-year-old man with widespread manifestation of warts and distinct pruritus for the last 5 years was diagnosed with a reactivated human papillomavirus (HPV) infection by three, genetically verified types (6, 16, 18), which are included in the vaccine Gardasil®. Conventional treatment was not successful, but a rapid and significant reduction of the skin manifestation was observed after vaccination with Gardasil®. To what extent therapy-resistant infections with HPV can be influenced through an active HPV vaccination should be investigated in future trials...
November 13, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29126806/modeling-the-consequences-of-regional-heterogeneity-in-human-papillomavirus-hpv-vaccination-uptake-on-transmission-in-switzerland
#9
Maurane Riesen, Victor Garcia, Nicola Low, Christian L Althaus
BACKGROUND: Completed human papillomavirus (HPV) vaccination by age 16 years among women in Switzerland ranges from 17 to 75% across 26 cantons. The consequences of regional heterogeneity in vaccination coverage on transmission and prevalence of HPV-16 are unclear. METHODS: We developed a deterministic, population-based model that describes HPV-16 transmission among young adults within and between the 26 cantons of Switzerland. We parameterized the model using sexual behavior data from Switzerland and data from the Swiss National Vaccination Coverage Survey...
November 7, 2017: Vaccine
https://www.readbyqxmd.com/read/29126591/parental-refusal-of-human-papillomavirus-vaccine-multisite-study
#10
Frances DiAnna Kinder
INTRODUCTION: The purpose of this study was to explore reasons why parents may refuse administration of the human papillomavirus vaccine to their children. The data from this multisite study will contribute to our understanding of why parents may refuse administration of the vaccine. METHODS: This mixed-methods study took place in several pediatric settings after a pilot study was completed. After a health visit in which the vaccine was refused, a survey was provided to the parent in a private room...
November 7, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29125554/antibody-competition-reveals-surface-location-of-hpv-l2-minor-capsid-protein-residues-17-36
#11
Stephanie M Bywaters, Sarah A Brendle, Kerstin P Tossi, Jennifer Biryukov, Craig Meyers, Neil D Christensen
The currently available nonavalent human papillomavirus (HPV) vaccine exploits the highly antigenic L1 major capsid protein to promote high-titer neutralizing antibodies, but is limited to the HPV types included in the vaccine since the responses are highly type-specific. The limited cross-protection offered by the L1 virus-like particle (VLP) vaccine warrants further investigation into cross-protective L2 epitopes. The L2 proteins are yet to be fully characterized as to their precise placement in the virion...
November 10, 2017: Viruses
https://www.readbyqxmd.com/read/29121792/are-you-covered-associations-between-patient-protection-and-affordable-care-act-knowledge-and-preventive-reproductive-service-use
#12
Ashlee N Sawyer, Melissa A Kwitowski, Eric G Benotsch
PURPOSE: Sexual and reproductive health conditions (eg, infections, cancers) represent public health concerns for American women. The present study examined how knowledge of the Patient Protection and Affordable Care Act (PPACA) relates to receipt of preventive reproductive health services among women. DESIGN: Cross-sectional online survey. SETTING: Online questionnaires were completed via Amazon Mechanical Turk, a crowdsourcing website where individuals complete web-based tasks for compensation...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29118082/health-literacy-approaches-to-improving-communication-between-dental-hygienists-and-patients-for-hpv-related-oral-cancer-prevention
#13
Erika L Thompson, Ellen M Daley, Cheryl A Vamos, Alice M Horowitz, Frank A Catalanotto, Rita D DeBate, Laura K Merrell, Stacey B Griner, Coralia Vazquez-Otero, Nolan S Kline
Purpose: Human Papillomavirus (HPV) has been identified as a causal agent for oropharyngeal cancers, suggesting a new role for dental hygienists in HPV-related cancer prevention strategies. Health literacy assessment is an approach that can be used to understand providers' informational assets and needs for educating and discussing HPV prevention with patients. This study aimed to understand dental hygienists' level of health literacy regarding HPV-related oropharyngeal cancers.Methods: Four focus group sessions with dental hygienists (n=48) were conducted at a national conference...
August 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29115958/to-vaccinate-or-not-to-vaccinate-perspectives-on-hpv-vaccination-among-girls-boys-and-parents-in-the-netherlands-a-q-methodological-study
#14
Nathalie J S Patty, Hanna Maria van Dijk, Iris Wallenburg, Roland Bal, Theo J M Helmerhorst, Job van Exel, Jane Murray Cramm
BACKGROUND: Despite the introduction of Human papillomavirus (HPV) vaccination in national immunization programs (NIPs), vaccination rates in most countries remain relatively low. An understanding of the reasons underlying decisions about whether to vaccinate is essential in order to promote wider spread of HPV vaccination. This is particularly important in relation to policies seeking to address shortfalls in current HPV campaigns. The aim of this study was to explore prevailing perspectives concerning HPV vaccination among girls, boys, and parents, and so to identify potential determinants of HPV vaccination decisions in these groups...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29115562/fungal-mannosylation-enhances-human-papillomavirus-16-e7-therapeutic-immunity-against-tc-1-tumors
#15
Zonglin Wang, Cuihua Wei, Yanjun Zhang, Wei Wang, Zheng Zhou, Gengfu Xiao
Cervical cancer, resulting from infection with human papillomavirus (HPV)16, remains the fourth most common cancer in women worldwide. Recently, three prophylactic HPV vaccines targeting high-risk HPVs (particularly HPV16 and HPV18) have been implemented to protect younger women. However, individuals with pre-existing infections have no benefit from prophylactic vaccines. Thus, there is an urgent need to develop therapeutic vaccines. HPV16 E7 has been widely utilized as a target for immune therapy of HPV16-associated lesions or cancers, reflecting the sustained existence of this virus in cancerous cells...
November 8, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29114884/dental-provider-practices-and-perceptions-regarding-adolescent-vaccination
#16
Allison L Naleway, Michelle L Henninger, Lisa A Waiwaiole, David M Mosen, Michael C Leo, Daniel J Pihlstrom
OBJECTIVE: To assess dental providers' clinical practices and perceptions regarding adolescent vaccinations. METHODS: We surveyed 234 dental providers in an integrated health care setting in Portland, Oregon, in March-April 2015. We assessed participants' knowledge of adolescent vaccines, barriers to recommending vaccines, and their perceived role in the promotion of vaccination and preventive medical care. RESULTS: Over 80 percent of respondents correctly identified influenza, tetanus-diphtheria-acellular pertussis, and human papillomavirus as vaccinations recommended for adolescents; 60 percent correctly identified meningococcal conjugate...
November 8, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/29110680/fraction-of-high-grade-cervical-intraepithelial-lesions-attributable-to-genotypes-targeted-by-a-nonavalent-hpv-vaccine-in-galicia-spain
#17
S Perez, A Iñarrea, R Pérez-Tanoira, M Gil, E López-Díez, O Valenzuela, M Porto, L Alberte-Lista, M A Peteiro-Cancelo, A Treinta, R Carballo, M C Reboredo, M E Alvarez-Argüelles, M J Purriños
BACKGROUND: Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The objective was to describe the fraction of squamous non-invasive high-grade cervical intraepithelial lesions attributable to genotypes targeted by bi-quadrivalent vaccines and by nonavalent vaccine according to age and diagnosis in women living in the city of Vigo (Galicia, Spain)...
November 6, 2017: Virology Journal
https://www.readbyqxmd.com/read/29110027/human-papillomavirus-vaccine-uptake-in-adolescence-and-adherence-to-cervical-cancer-screening-in-switzerland-a-national-cross-sectional-survey
#18
Monica N Wymann, Anne Spaar Zographos, Ekkehardt Altpeter, Virginie Masserey Spicher, Nicola Low, Mirjam Mäusezahl-Feuz
OBJECTIVES: The objectives were to measure uptake of and factors associated with human papillomavirus (HPV) vaccination initiation and to determine whether HPV vaccination reduced the uptake of cervical cancer screening. METHODS: We conducted a cross-sectional survey in a random sample of Swiss women aged 18-49 years in 2014 (N = 3588). RESULTS: Vaccination initiation was 69.3% and full coverage (three doses) 54.1% for 18-20-year olds, respectively, 42...
November 6, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/29108943/therapeutic-hpv-vaccines
#19
REVIEW
Gemma Hancock, Karin Hellner, Lucy Dorrell
High-risk human papillomavirus (HPV) infection is known to be a necessary factor for cervical and anogenital malignancies. Cervical cancers account for over a quarter of a million deaths annually. Despite the availability of prophylactic vaccines, HPV infections remain extremely common worldwide. Furthermore, these vaccines are ineffective at clearing pre-existing infections and associated preinvasive lesions. As cervical dysplasia can regress spontaneously, a therapeutic HPV vaccine that boosts host immunity could have a significant impact on the morbidity and mortality associated with HPV...
September 28, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29105738/five-year-relative-survival-for-human-papillomavirus-associated-cancer-sites
#20
Hilda Razzaghi, Mona Saraiya, Trevor D Thompson, S Jane Henley, Laura Viens, Reda Wilson
BACKGROUND: Human papillomavirus (HPV) vaccines can potentially prevent greater than 90% of cervical and anal cancers as well as a substantial proportion of vulvar, vaginal, penile, and oropharyngeal cancers caused by certain HPV types. Because more than 38,000 HPV-associated cancers are diagnosed annually in the United States, current studies are needed to understand how relative survival varies for each of these cancers by certain demographic characteristics, such as race and age. METHODS: The authors examined high-quality data from 27 population-based cancer registries covering approximately 59% of the US population...
November 6, 2017: Cancer
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