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papillomavirus and vaccine

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https://www.readbyqxmd.com/read/29781877/human-papillomavirus-genotypes-in-invasive-cervical-carcinoma-in-hiv-seropositive-and-seronegative-women-in-zimbabwe
#1
Washington Mudini, Joel Michael Palefsky, Martin John Hale, Michael Zvavahera Chirenje, Rudo Tanyaradzwa Makunike-Mutasa, Fiona Mutisi, Alltalents Murahwa, Altini Mario
BACKGROUND: Invasive cervical carcinoma (ICC) accounts for 23% of all cancer-related deaths in Zimbabwean women. Trials for a national program of genotype-specific HPV vaccines are underway to prevent cervical carcinoma, but the distribution of HPV types among women with ICC according to HIV status is unknown. METHODS: To determine prevalence and distribution of high-risk HPV genotypes by HIV status in women with ICC, we performed a cross-sectional study on women referred for ICC testing at four urban referral hospitals in Zimbabwe from June 2014 - December 2015...
May 16, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29781465/hpv-literacy-the-role-of-english-proficiency-in-korean-american-immigrant-women
#2
Hee Yun Lee, Y Joon Choi, Young Ji Yoon, Jennifer Oh
BACKGROUND: Although Korean American women have one of the highest cervical cancer incidence and mortality rates among all Asian American and non-Hispanic White women, they are less likely to receive the human papillomavirus (HPV) vaccine to prevent cervical cancer. OBJECTIVES: This study aimed to examine Korean American women's HPV literacy and factors related to HPV literacy to identify targeted intervention strategies. METHODS: A quota sampling strategy was used to recruit 243 Korean American women aged 19-85 years in the Atlanta, Georgia, metropolitan area...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29781414/prevalence-of-human-papillomavirus-types-associated-with-cervical-lesions-in-sergipe-state-northeastern-brazil-high-frequency-of-a-possibly-carcinogenic-type
#3
I G S S Serra, E D Araujo, G S Barros, F L S G Santos, R Q Gurgel, M V A Batista
Persistent infection with high-risk human papillomavirus (HPV) is the main cause of cervical cancer and the prevalence of HPV types varies depending on the geographic region. Therefore, this study assessed the prevalence of HPV types in women with cervical lesions from Sergipe state, Northeastern Brazil. A cross-sectional study was conducted in women with cervical lesions from March to December 2014. These lesions were investigated by PCR and HPV types were identified by DNA sequencing. 432 patients were included, of which 337 patients tested positive for HPV...
May 21, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29780771/proposal-for-cervical-cancer-screening-in-the-era-of-hpv-vaccination
#4
REVIEW
Yung-Taek Ouh, Jae Kwan Lee
Eradication of cervical cancer involves the expansion of human papillomavirus (HPV) vaccine coverage and the development of efficient screening guidelines that take vaccination into account. In Korea, the HPV National Immunization Program was launched in 2016 and is expected to shift the prevalence of HPV genotypes in the country, among other effects. The experiences of another countries that implement national immunization programs should be applied to Korea. If HPV vaccines spread nationwide with broader coverage, after a few decades, cervical intraepithelial lesions or invasive cancer should become a rare disease, leading to a predictable decrease in the positive predictive value of cervical screening cytology...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29780768/lack-of-school-requirements-and-clinician-recommendations-for-human-papillomavirus-vaccination
#5
Linda M Niccolai, Anna L North, Alison Footman, Caitlin E Hansen
Background: A strong recommendation from a clinician is one of the best predictors of human papillomavirus (HPV) vaccination among adolescents, yet many clinicians do not provide effective recommendations. The objective of this study was to understand how the lack of school entry requirements for HPV vaccination influences clinicians' recommendations. Design and Methods: Semi-structured interviews with a purposive sample of 32 clinicians were conducted in 2015 in Connecticut USA...
February 5, 2018: Journal of Public Health Research
https://www.readbyqxmd.com/read/29778519/decline-of-hpv-infections-in-scandinavian-cervical-screening-populations-after-introduction-of-hpv-vaccination-programs
#6
Joakim Dillner, Mari Nygård, Christian Munk, Maria Hortlund, Bo T Hansen, Camilla Lagheden, Kai-Li Liaw, Susanne K Kjaer
OBJECTIVE: To monitor the changes in prevalence of human papillomavirus (HPV) infections in women <50 years of age, participating in cervical screening programs of Denmark, Norway, and Sweden, before and after introduction of quadrivalent HPV (qHPV) vaccination. METHODS: Liquid-based cytology samples were collected from 6538 women who attended cervical screening in Denmark, Norway, and Sweden in 2006-2008 and from 6332 similarly enrolled women in 2012-2013...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29778518/an-innovative-medical-school-curriculum-to-address-human-papillomavirus-vaccine-hesitancy
#7
Abigail M Schnaith, Erica M Evans, Caleb Vogt, Andrea M Tinsay, Thomas E Schmidt, Katelyn M Tessier, Britt K Erickson
BACKGROUND: Vaccination rates against Human Papillomavirus (HPV) in the US remain alarmingly low. Physicians can significantly influence a parent's decision to vaccinate their children. However, medical education often lacks training on specific strategies for communicating with vaccine hesitant parents. METHODS: We created an innovative curriculum designed to teach medical students how to address HPV vaccine hesitancy. The curriculum consisted of (1) a presentation on the epidemiology, biology, and disease morbidity associated with HPV, (2) a video that teaches specific communication strategies and (3) role-playing simulations...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29778516/facilitators-of-and-barriers-to-hpv-vaccination-among-sexual-and-gender-minority-patients-at-a-boston-community-health-center
#8
Kaan Z Apaydin, Holly B Fontenot, Derri Shtasel, Sannisha K Dale, Christina P C Borba, Christopher S Lathan, Lori Panther, Kenneth H Mayer, Alex S Keuroghlian
BACKGROUND: Young sexual minority individuals have lower human papillomavirus (HPV) vaccine completion rates than the general population, and little is known about how gender minority people perceive HPV vaccination. The aim of this study was to qualitatively identify patient-, provider-, and systems-level barriers and facilitators for HPV vaccination among sexual and gender minority (SGM) people. METHODS: Fifteen SGM-identified individuals, ages 23-26, were recruited at an urban community health center in Boston, MA, that specializes in care for SGM...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29778314/trends-in-high-grade-cervical-cancer-precursors-in-the-human-papillomavirus-vaccine-era
#9
Fredrick Oakley, Mohamed M Desouki, Manideepthi Pemmaraju, Julia M Gargano, Lauri E Markowitz, Martin Steinau, Elizabeth R Unger, Yuwei Zhu, Oluwole Fadare, Marie R Griffin
INTRODUCTION: The 2006 introduction of human papillomavirus vaccine targeted against genotypes 6, 11, 16, and 18 should result in decreased cervical dysplasia in vaccinated women. However, new cervical cancer guidelines to increase screening intervals complicate interpretation of trends. The hypothesis is that cervical dysplasia would decrease only in young vaccine-eligible women, and not older women. METHODS: The authors identified Davidson County, Tennessee, women aged 18-39 years with cervical intraepithelial neoplasia (CIN) grade 2 or greater and adenocarcinoma in situ, denoted as CIN2+, through pathology reports from laboratories serving this population...
May 16, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29773702/exploring-variation-in-human-papillomavirus-vaccination-uptake-in-switzerland-a-multilevel-spatial-analysis-of-a-national-vaccination-coverage-survey
#10
Maurane Riesen, Garyfallos Konstantinoudis, Phung Lang, Nicola Low, Christoph Hatz, Mirjam Maeusezahl, Anne Spaar, Marc Bühlmann, Ben D Spycher, Christian L Althaus
OBJECTIVE: Understanding the factors that influence human papillomavirus (HPV) vaccination uptake is critically important to the design of effective vaccination programmes. In Switzerland, HPV vaccination uptake (≥1 dose) by age 16 years among women ranges from 31% to 80% across 26 cantons (states). Our objective was to identify factors that are associated with the spatial variation in HPV vaccination uptake. METHODS: We used cross-sectional data from the Swiss National Vaccination Coverage Survey 2009-2016 on HPV vaccination status (≥1 dose) of 14-17-year-old girls, their municipality of residence and their nationality for 21 of 26 cantons (n=8965)...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29772848/increased-vaccination-coverage-among-adolescents-and-young-adults-in-the-district-of-palermo-as-a-result-of-a-public-health-strategy-to-counteract-an-epidemic-panic
#11
Claudio Costantino, Vincenzo Restivo, Gianmarco Ventura, Claudio D'Angelo, Maria Angela Randazzo, Nicolò Casuccio, Mario Palermo, Alessandra Casuccio, Francesco Vitale
During the summer of 2016 four cases of invasive meningococcal disease in rapid succession among young adults in the district of Palermo, Italy, resulting in one death, were widely reported by local and national mass media. The resultant 'epidemic panic' among the general population overloaded the vaccination units of the Palermo district over the following months. Strategies implemented by the Sicilian and local public health authorities to counteract 'meningitis fear' included the following: (a) extension of active and free-of-charge anti-meningococcal tetravalent vaccination from age class 12⁻18 to 12⁻30 years old; (b) implementation of vaccination units during normal clinic hours in rooms tailored for vaccine administration; (c) development of informative institutional tools and timely communication throughout local mass media to reassure the general population...
May 17, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29771616/predictors-of-human-papillomavirus-vaccine-follow-through-among-privately-insured-us-patients
#12
Jennifer C Spencer, Noel T Brewer, Justin G Trogdon, Stephanie B Wheeler, Stacie B Dusetzina
OBJECTIVES: To assess predictors of timely human papillomavirus (HPV) vaccine follow-through among privately insured individuals initiating the 3-dose series. METHODS: Using MarketScan Commercial claims data, we identified 1 332 217 privately insured US individuals aged 9 to 26 years who initiated the bivalent or quadrivalent HPV vaccine series from 2006 to 2014, with follow-up data extending through 2015. The study outcome was receipt of third HPV dose within 12 months of the first, compared by year of initiation...
May 17, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29770129/cutaneous-papillomaviruses-and-non-melanoma-skin-cancer-causal-agents-or-innocent-bystanders
#13
REVIEW
Daniel Hasche, Sabrina E Vinzón, Frank Rösl
There is still controversy in the scientific field about whether certain types of cutaneous human papillomaviruses (HPVs) are causally involved in the development of non-melanoma skin cancer (NMSC). Deciphering the etiological role of cutaneous HPVs requires - besides tissue culture systems - appropriate preclinical models to match the obtained results with clinical data from affected patients. Clear scientific evidence about the etiology and underlying mechanisms involved in NMSC development is fundamental to provide reasonable arguments for public health institutions to classify at least certain cutaneous HPVs as group 1 carcinogens...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29770079/summary-of-the-naci-update-on-the-recommended-use-of-human-papillomavirus-hpv-vaccine-nine-valent-hpv-vaccine-two-dose-immunization-schedule-and-the-use-of-hpv-vaccines-in-immunocompromised-populations
#14
S L Deeks, M C Tunis, S Ismail
Background: Human papillomavirus (HPV) infections are the most common sexually transmitted infections. In the absence of vaccination, it is estimated that 75% of sexually active Canadians will have an HPV infection at some point in their lives. HPV vaccine programs were first recommended by Canada's National Advisory Committee on Immunization (NACI) in 2007. In addition to the existing HPV vaccine options in Canada, NACI recently recommended the use of a newly authorized nine-valent HPV (HPV9) vaccine according to a 3-dose immunization schedule for the prevention of HPV types 6-, 11-, 16-, 18-, 31-, 33-, 45-, 52- and 58-related cancers and anogenital warts in females aged 9 to 45 years and males aged 9 to 26 years...
June 1, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29767739/efficacy-immunogenicity-and-safety-of-a-9-valent-human-papillomavirus-vaccine-subgroup-analysis-of-participants-from-asian-countries
#15
S M Garland, P Pitisuttithum, H Y S Ngan, C-H Cho, C-Y Lee, C-A Chen, Y C Yang, T-Y Chu, N-F Twu, R Samakoses, Y Takeuchi, T H Cheung, S C Kim, L-M Huang, B-G Kim, Y-T Kim, K-H Kim, Y-S Song, S Lalwani, J-H Kang, M Sakamoto, H-S Ryu, N Bhatla, H Yoshikawa, M C Ellison, S R Han, E Moeller, S Murata, M Ritter, M Sawata, C Shields, A Walia, G Perez, A Luxembourg
Background: A 9-valent human papillomavirus-6/11/16/18/31/33/45/52/58 (9vHPV) vaccine extends coverage to 5 next most common oncogenic types (31/33/45/52/58) in cervical cancer versus quadrivalent HPV (qHPV) vaccine. We describe efficacy, immunogenicity, and safety in Asian participants (India, Hong Kong, South Korea, Japan, Taiwan, and Thailand) from 2 international studies: a randomized, double-blinded, qHPV vaccine-controlled efficacy study (young women aged 16-26 years; NCT00543543; Study 001); and an immunogenicity study (girls and boys aged 9-15 years; NCT00943722; Study 002)...
May 15, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29765009/parent-provider-communication-of-hpv-vaccine-hesitancy
#16
Laura A Shay, Austin S Baldwin, Andrea C Betts, Emily G Marks, Robin T Higashi, Richard L Street, Donna Persaud, Jasmin A Tiro
: media-1vid110.1542/5754332185001PEDS-VA_2017-2312 Video Abstract OBJECTIVES: To prevent human papillomavirus (HPV)-related cancers, providers must effectively communicate with HPV vaccine-hesitant parents. Here, we developed a typology characterizing parent-provider communication around HPV vaccine hesitancy. METHODS: We audio-recorded 43 visits with unvaccinated adolescents at 6 pediatric clinics in Dallas, Texas in which parents were undecided about HPV vaccination. We qualitatively coded how parents verbally expressed hesitancy (assertive response, asking a question, or expressing concern) and whether providers responded with acquiescence (agree to defer vaccination) and/or persistence (continue discussion)...
May 15, 2018: Pediatrics
https://www.readbyqxmd.com/read/29762430/the-impact-of-varying-numbers-of-quadrivalent-human-papillomavirus-vaccine-doses-on-anogenital-warts-in-the-united-states-a-database-study
#17
Burak Zeybek, Yu-Li Lin, Yong-Fang Kuo, Ana M Rodriguez
OBJECTIVE: The aim of the study was to investigate the effects of 3 or less quadrivalent human papillomavirus (HPV) vaccine doses on anogenital warts in both males and females in the United States. MATERIALS AND METHODS: We conducted a retrospective database study that included males and females aged 9 to 26 years who received varying numbers of vaccine doses between 2006 and 2015. The primary outcome was the incidence of anogenital warts starting 3 months after the last dose of the HPV vaccine...
May 8, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29761782/-vulvar-intraepithelial-neoplasia
#18
Signe Østergård, Christina Steen Vorbeck, Mette Meinert
Vulvar intraepithelial neoplasia (VIN) is a rare but premalig-nant condition. VIN has two aetiological pathways: a human papillomavirus (HPV)-dependent pathway, which is a vulvar high-grade squamous intraepithelial lesion (HSIL), and an HPV-independent pathway, called differentiated VIN (d-VIN), associated with lichen sclerosus. d-VIN is more aggressive than vulvar HSIL. In case of symptoms, a biopsy should be performed. The recurrence risk is high: 25-50% regardless of treatment type. We recommend treatment with imiquimod as first choice to avoid mutilating surgery...
May 14, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29761723/knowledge-and-attitudes-regarding-hpv-and-vaccination-among-chinese-women-aged-20-to-35-years-in-fujian-province-a-cross-sectional-study
#19
Lihua Chen, Yiyi Song, Guanyu Ruan, Qiaoyu Zhang, Fen Lin, Jun Zhang, Ting Wu, Jian An, Binhua Dong, Pengming Sun
The use of the human papillomavirus (HPV) vaccine was recently approved in Mainland China. This study determined the knowledge and attitudes of young women aged 20 to 35 years in Fujian Province, China, with regard to HPV and vaccination and explored the potential factors influencing their attitudes toward HPV vaccination. This was a cross-sectional study that collected data regarding the knowledge on and attitudes toward HPV and vaccination using questionnaires. Furthermore, the prevalence of HPV was determined from the sampled participants...
January 2018: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/29759001/betwixt-and-between-well-and-sick-in-cervical-precancer-canadian-women-s-experiences-of-recurring-hpv-infections-and-hpv-vaccination
#20
Michelle Wyndham-West, Nancy Durand, Aimee Santoro
Background This research fuses the experiences of a precancer diagnosis with the decision-making surrounding a vaccine that can protect against human papillomavirus strains that women may not have been exposed to. The interviewee cohort is of note as half the women were in their 30s and 40s and 75% were over the age of 26. These groupings are often overlooked in media discourses and narrative research surrounding human papillomavirus and the human papillomavirus vaccine. Purpose Womens' diagnoses and treatment experiences, including colposcopies, biopsies, and Loop Electrosurgical Excision Procedures, are chronicled to highlight a liminal, precancerous state-one in which they are not deemed healthy, but nor have they been diagnosed with cancer...
January 1, 2018: Canadian Journal of Nursing Research, Revue Canadienne de Recherche en Sciences Infirmières
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