keyword
MENU ▼
Read by QxMD icon Read
search

Running medicine

keyword
https://www.readbyqxmd.com/read/29149735/carbamazepine-lamotrigine-levetiracetam-and-valproic-acid-in-dried-blood-spots-with-liquid-chromatography-tandem-mass-spectrometry-method-development-and-validation
#1
Camilla Linder, Anna Hansson, Sara Sadek, Lars L Gustafsson, Anton Pohanka
Monitoring of antiepileptic drugs in children with epilepsy require multiple visits at a clinic for blood collection. Dried blood spot sampling is an alternative way of collection, performed at home by self-collection and can save time and costs for patients and family members. The aim was to develop and validate an LC-MS/MS dried blood spot method for carbamazepine, lamotrigine, levetiracetam and valproic acid with the requirements of using standard equipment and material in a routine laboratory setting. Whatman-903 filter paper was utilized, and discs were punched into a 96 well plate with an automated puncher and barcode reading...
November 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29143393/an-algorithm-to-detect-unexpected-increases-in-frequency-of-reports-of-adverse-events-in-eudravigilance
#2
Luis C Pinheiro, Gianmario Candore, Cosimo Zaccaria, Jim Slattery, Peter Arlett
PURPOSE: The European Medicines Agency developed an algorithm to detect unexpected increases in frequency of reports, to enhance the ability to detect adverse events that manifest as increases in frequency, in particular quality defects, medication errors, and cases of abuse or misuse. METHODS: An algorithm based on a negative binomial time-series regression model run on 6 sequential observations prior to the monitored period was developed to forecast monthly counts of reports...
November 16, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29138128/will-participatory-syndromic-surveillance-work-in-latin-america-piloting-a-mobile-approach-to-crowdsource-influenza-like-illness-data-in-guatemala
#3
José Tomás Prieto, Jorge H Jara, Juan Pablo Alvis, Luis R Furlan, Christian Travis Murray, Judith Garcia, Pierre-Jean Benghozi, Susan Cornelia Kaydos-Daniels
BACKGROUND: In many Latin American countries, official influenza reports are neither timely nor complete, and surveillance of influenza-like illness (ILI) remains thin in consistency and precision. Public participation with mobile technology may offer new ways of identifying nonmedically attended cases and reduce reporting delays, but no published studies to date have assessed the viability of ILI surveillance with mobile tools in Latin America. We implemented and assessed an ILI-tailored mobile health (mHealth) participatory reporting system...
November 14, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29121662/qualitative-and-quantitative-assessment-of-illumina-s-forensic-str-and-snp-kits-on-miseq-fgx%C3%A2
#4
Vishakha Sharma, Hoi Yan Chow, Donald Siegel, Elisa Wurmbach
Massively parallel sequencing (MPS) is a powerful tool transforming DNA analysis in multiple fields ranging from medicine, to environmental science, to evolutionary biology. In forensic applications, MPS offers the ability to significantly increase the discriminatory power of human identification as well as aid in mixture deconvolution. However, before the benefits of any new technology can be employed, a thorough evaluation of its quality, consistency, sensitivity, and specificity must be rigorously evaluated in order to gain a detailed understanding of the technique including sources of error, error rates, and other restrictions/limitations...
2017: PloS One
https://www.readbyqxmd.com/read/29121542/risk-factors-for-three-month-mortality-after-discharge-in-a-cohort-of-non-oncologic-hospitalized-elderly-patients-results-from-the-reposi-study
#5
Luca Pasina, Laura Cortesi, Mara Tiraboschi, Alessandro Nobili, Giovanna Lanzo, Mauro Tettamanti, Carlotta Franchi, Pier Mannuccio Mannucci, Silvia Ghidoni, Andrea Assolari, Antonio Brucato
BACKGROUND: Short-term prognosis, e.g. mortality at three months, has many important implications in planning the overall management of patients, particularly non-oncologic patients in order to avoid futile practices. The aims of this study were: i) to investigate the risk of three-month mortality after discharge from internal medicine and geriatric wards of non-oncologic patients with at least one of the following conditions: permanent bedridden status during the hospital stay; severely reduced kidney function; hypoalbuminemia; hospital admissions in the previous six months; severe dementia; ii) to establish the absolute risk difference of three-month mortality of bedridden compared to non-bedridden patients...
November 6, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29115906/challenges-of-running-a-gmp-facility-for-regenerative-medicine-in-a-public-hospital
#6
Mariele Viganò, Rosaria Giordano, Lorenza Lazzari
Advanced therapy medicinal products represent a new generation of medicinal products for regenerative medicine. Since the implementation of the EU regulation for this innovative class of drugs, the academic and hospital institutions have played a central role in their development and manufacture. For these institutions that are not familiar with the industrial context, being in compliance with the pharmaceutical standards is extremely challenging. This report describes how we dealt with some specific issues during our hospital-based GMP experience...
November 8, 2017: Regenerative Medicine
https://www.readbyqxmd.com/read/29114552/introduction-to-clinical-pathology-a-brief-course-of-laboratory-medicine-in-the-field-for-medical-students
#7
Navid Omidifar, Ali Keshtkari, Mohammadreza Dehghani, Mansoureh Shokripour
OBJECTIVES: Teaching of clinical pathology to medical students has been ignored in many countries such as Iran. We aim to introduce a practical brief course and its proper timing. MATERIALS AND METHODS: Three groups of medical students from consecutive years of entrance passed a 1.5 working day practical course on the field. Their level of knowledge was assessed by pre- and post-tests. Their idea and satisfaction were gathered by questionnaires. RESULTS: Knowledge of students became significantly higher after the course...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29105237/scientism-conflicts-of-interest-and-the-marginalization-of-ethics-in-medical-education
#8
Christopher Mayes, Jane Williams, Ian Kerridge, Wendy Lipworth
AIM: This paper reports on the findings from 6 focus groups conducted with Australian medical students. The focus groups sought students' perspectives on how the influence of commercial interests on medical practice and education could be managed. METHOD: We conducted 6 focus groups with medical students in New South Wales, Australia. Participants were recruited via student-run medical society and faculty e-mail lists. Forty-nine students from 6 medical schools in New South Wales participated...
November 3, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29090483/a-1-minute-full-brain-mr-exam-using-a-multicontrast-epi-sequence
#9
Stefan Skare, Tim Sprenger, Ola Norbeck, Henric Rydén, Lars Blomberg, Enrico Avventi, Mathias Engström
PURPOSE: A new multicontrast echo-planar imaging (EPI)-based sequence is proposed for brain MRI, which can directly generate six MR contrasts (T1 -FLAIR, T2 -w, diffusion-weighted (DWI), apparent diffusion coefficient (ADC), T2*-w, T2 -FLAIR) in 1 min with full brain coverage. This could enable clinical MR clinical screening in similar time as a conventional CT exam but with more soft-tissue information. METHODS: Eleven sequence modules were created as dynamic building blocks for the sequence...
October 31, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29084328/effects-of-group-fitness-classes-on-stress-and-quality-of-life-of-medical-students
#10
Dayna M Yorks, Christopher A Frothingham, Mark D Schuenke
Context: Medical school can produce intense psychological distress in its students; however, there is a paucity of research exploring potential means of improving medical students' well-being. Objective: To investigate the relationship between physical exercise and stress and quality of life (QOL) in a medical student population. Methods: This nonrandomized, controlled, 12-week study used a survey research design. First- and second-year osteopathic medical students at the University of New England College of Osteopathic Medicine were recruited to participate in 1 of 3 groups: (1) students participating in 30-minute CXWORX (Les Mills International LTD) group fitness classes; (2) students exercising alone or with up to 2 additional partners regularly (eg, running, weight lifting), henceforth called the health-enhancement group; and (3) students in a control group who did not engage in regular exercise...
November 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29082710/-how-to-adapt-to-the-requirements-of-clinical-value-oriented-drug-innovation-for-pharmaceutical-research-in-application-process-of-new-traditional-chinese-medicine
#11
Fang Jin
On August 9, 2015, the State Council promulgated the "Opinions of the State Council on the reform of drug and medical device review and approval system" (Guofa 2015 No. 44), and established the "clinical value-oriented drug innovation" model to encourage the research and development of new drugs. Following that, China Food and Drug Administration (CFDA) promulgated the "Notice on several policies for drug registration review and approval" (2015 No. 230 ) on November 11, 2015, clearly specifying that CFDA would "implement one-time approval for clinical trials application of the new drugs, and no longer take a phased declaration, review and approval system; for the new drugs that apply for clinical trials, mainly review the scientific natureof the clinical protocols and the risk control of the new drugs to guarantee the safety of subjects"...
May 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29073988/drug-policy-in-bulgaria
#12
Antoniya Dimova, Maria Rohova, Elka Atanasova, Paweł Kawalec, Katarzyna Czok
Bulgaria has a mixed public-private health care financing system. Health care is financed mainly from compulsory health insurance contributions and out-of-pocket payments. Out-of-pocket payments constitute a large share of the total health care expenditure (44.14% in 2014). The share of drugs expenditure for outpatient treatment was 42.3% of the total health care expenditure in 2014, covered mainly by private payments (78.6% of the total pharmaceutical expenditure). The drug policy is run by the Ministry of Health (MoH), the National Council on Prices and Reimbursement of Medicinal Products, and the Health Technology Assessment Commission...
September 2017: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29073318/bedside-assessment-of-the-necessity-of-daily-lab-testing-for-patients-nearing-discharge
#13
Surafel Tsega, Michelle O'Connor, Jashvant Poeran, Colin Iberti, Hyung J Cho
As part of the Choosing Wisely® campaign, the Society of Hospital Medicine recommends against performing "repetitive complete blood count chemistry testing in the face of clinical and lab stability." With this recommendation as a framework, we targeted 2 hospitalist-run inpatient medicine units that employed bedside, scripted, interdisciplinary rounds. Our multifaceted intervention included prompting the hospitalist to identify clinically stable patients for next-day discharge and to discontinue labs when appropriate...
October 18, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29073202/questionnaire-survey-of-the-pan-african-trade-in-lion-body-parts
#14
Vivienne L Williams, Andrew J Loveridge, David J Newton, David W Macdonald
The African lion is in decline across its range, and consumptive utilisation and trade of their body parts and skins has been postulated as a cause for concern. We undertook a pan-African questionnaire and literature survey to document informed opinion and evidence for the occurrence of domestic and international trade and consumption in African lion body parts across current and former range states. Sixty-five people from 18 countries participated in the online questionnaire survey (run from July 2014 to May 2015), with information provided for 28 countries (including 20 out of 24 countries believed to have extant populations)...
2017: PloS One
https://www.readbyqxmd.com/read/29071845/-review-on-advantages-and-evidence-of-treating-and-preventing-urinary-tract-infection-in-traditional-chinese-medicine
#15
Guo-Yong Yu, Zhe-Jing Tian, Yue Sun, Han-Wen Yang, Shuai-Jie Han, Run-Pei Miao, Xin-Wen Fu, Min Xiong, Yao-Xian Wang, Jun-Jian Tian
Urinary tract infection (UTI) in traditional Chinese medicine (TCM) belongs to the category of stranguria. This article describes the unsatisfactory situations in clinical practice such as antibiotics abuse, increasing of drug-resistant bacteria, high recurrence rate, etc. According to evidence-based medicine, literatures as evidence are collected for summarizing and analyzing and the result shows the advantages of TCM of relieving symptoms, reducing the dosage of antibiotics, less side effects, lower recurrence rate, etc...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29061472/quantification-of-steroid-hormones-in-human-serum-by-liquid-chromatography-high-resolution-tandem-mass-spectrometry
#16
Silke Matysik, Gerhard Liebisch
A limited specificity is inherent to immunoassays for steroid hormone analysis. To improve selectivity mass spectrometric analysis of steroid hormones by liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been introduced in the clinical laboratory over the past years usually with low mass resolution triple-quadrupole instruments or more recently by high resolution mass spectrometry (HR-MS). Here we introduce liquid chromatography-high resolution tandem mass spectrometry (LC-MS/HR-MS) to further increase selectivity of steroid hormone quantification...
December 1, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29060430/concussion-management-application-for-amateur-sports
#17
J D Fischer, G H Smith, R S Rodrigues, M R Afzal, D J van den Heever, P L Viviers, J T Viljoen
Concussion management has become one of the most popular topics in sports medicine. Significant resources are being invested in developing protocols for professional sport associations such as the NFL and FIFA. These protocols are often expensive and require substantial resources to implement. The problem, however, runs much deeper than just professional sports. Currently there exists little infrastructure to effectively manage concussion in amateur settings such as high school, club and university sport. A more holistic approach is required to ensure that the same standard of concussion management is being implemented across the board, regardless of the available medical and financial resources...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059802/problem-based-learning-for-engineering
#18
Dinesh Kumar, Pj Radcliffe
the role of Problem Based Learning (PBL) is relative clear in domains such as medicine but its efficacy in engineering is as yet less certain. To clarify the role of PBL in engineering, a 3 day workshop was conducted for senior Brazilian engineering academics where they were given the theory and then an immersive PBL experience. One major purpose for running this workshop was for them to identify suitable courses where PBL could be considered. During this workshop, they were split in teams and given a diverse range of problems...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29045617/purification-of-four-flavonoid-glycosides-from-lotus-nelumbo-nucifera-gaertn-plumule-by-macroporous-resin-combined-with-hsccc
#19
Lei Wu, Wei Xiong, Ju-Wu Hu, Zhen Gu, Jian-Guo Xu, Chuan-Ling Si, Young-Soo Bae, Gang Xu
High-speed counter-current chromatography (HSCCC) combined with macroporous resin (MR) column was successfully applied to the isolation and purification of four flavonoid glycosides from the medicinal herb Lotus plumule (LP). A polar two-phase solvent system composed of ethyl acetate-n-butanol-water (1:2:3, v/v/v) was selected by high-performance liquid chromatography (HPLC) and run on a preparative scale where the lower aqueous phase was used as the mobile phase with a head-to-tail elution mode. Quercetin-3-O-β-D-glucopyranoside (15 mg), isorhamnetin-3-O-β-D-glucopyranoside (13 mg), apigenin 6-C-β-D-glucopyranosyl-8-C-α-L-arabinopyranoside (18 mg) and apigenin 6,8-di-C-β-D-glucopyranoside (48 mg) were obtained in a one-step HSCCC separation from 240 mg of the sample...
October 17, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29041796/prevalence-of-eye-pathology-in-a-group-of-diabetic-patients-at-national-district-hospital-outpatient-department-in-bloemfontein-south-africa
#20
Joleen P Cairncross, Wilhelm J Steinberg, Mathys J Labuschagne
BACKGROUND: Diabetic retinopathy is the third most common cause of blindness after cataracts and glaucoma in South Africa. Primary healthcare interventions providing eye care services play an important role in preventing complications. AIM: To determine the prevalence of eye pathology in a group of diabetic patients at National District Hospital by screening for diabetes-associated ocular pathology. SETTING: Outpatients Department run by Department of Family Medicine at National District Hospital in Bloemfontein from June to July 2014...
September 27, 2017: African Journal of Primary Health Care & Family Medicine
keyword
keyword
32295
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"