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https://www.readbyqxmd.com/read/28206993/hemodynamic-effects-of-sodium-bicarbonate-administration
#1
A C Katheria, M K Brown, K Hassan, D M Poeltler, D A Patel, V K Brown, J B Sauberan
OBJECTIVE: To describe the hemodynamic changes that occur with sodium bicarbonate (NaHCO3) administration in premature neonates. STUDY DESIGN: This retrospective study included premature neonates 23 to 31+6 weeks of gestational age who underwent continuous cardiac and cerebral monitoring as participants in prospective trials at our institution, and who received NaHCO3 infused over 30 min in the first 24 h of life. Blood pressure (BP), heart rate, cardiac output (CO), SpO2 and cerebral oximetry (StO2) were captured every 2 s...
February 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28151429/the-influence-of-adipose-tissue-on-spatially-resolved-near-infrared-spectroscopy-derived-skeletal-muscle-oxygenation-the-extent-of-the-problem
#2
Victor M Niemeijer, Jasper Jansen, Thomas van Dijk, Ruud Spee, Eduard Meijer, Hareld Kemps, Pieter Wijn
OBJECTIVE: Near-infrared spectroscopy (NIRS) measurements of tissue oxygen saturation (StO2) are useful for the assessment of skeletal muscle perfusion and function during exercise, however, they are influenced by overlying skin and adipose tissue. This study explored the extent and nature of the influence of adipose tissue thickness (ATT) on StO2. APPROACH: NIR spatially resolved spectroscopy (SRS) derived oxygenation was measured on vastus lateralis in 56 patients with chronic heart failure (CHF) and 20 healthy control (HC) subjects during rest and moderate intensity exercise with simultaneous assessment of oxygen uptake kinetics (tauVO2onset)...
February 2, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28093233/changes-in-vascular-responsiveness-during-a-hyperglycemia-challenge-measured-by-near-infrared-spectroscopy-vascular-occlusion-test
#3
Rogério Nogueira Soares, Raylene A Reimer, Juan Manuel Murias
BACKGROUND: Postprandial hyperglycemia is associated with impaired vascular responsiveness. Recent studies have established the use of a near-infrared spectroscopy (NIRS)-derived approach, combined with a vascular occlusion test (VOT), to examine vascular responsiveness within the microvasculature in normoglycemia. The aim of this study was to examine whether this NIRS-VOT technique could detect differences in vascular responsiveness following a hyperglycemic challenge. METHODS AND RESULTS: Fourteen young healthy individuals participated in the study...
January 14, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28027790/the-impact-of-red-blood-cell-storage-duration-on-tissue-oxygenation-in-cardiac-surgery
#4
Christopher P Stowell, Glenn Whitman, Suzanne Granger, Hernando Gomez, Susan F Assmann, Michael J Massey, Nathan I Shapiro, Marie E Steiner, Elliott Bennett-Guerrero
OBJECTIVE: Although storage alters red blood cells, several recent, randomized trials found no differences in clinical outcomes between patients transfused with red blood cells stored for shorter versus longer periods of time. The objective of this study was to see whether storage impairs the in vivo ability of erythrocytes to traverse the microcirculation and deliver oxygen at the tissue level. METHODS: A subset of subjects from a clinical trial of cardiac surgery patients randomized to receive transfusions of red blood cells stored ≤10 days or ≥21 days were assessed for thenar eminence and cerebral tissue hemoglobin oxygen saturation (StO2) via the use of near-infrared spectroscopy and sublingual microvascular blood flow via side-stream darkfield videomicroscopy...
November 19, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28008565/broadband-near-infrared-spectroscopy-can-detect-cyanide-induced-cytochrome-aa3-inhibition-in-rats-a-proof-of-concept-study
#5
Robert H Thiele, Keita Ikeda, Yunzhen Wang, Raquel R Bartz, Zhiyi Zuo
PURPOSE: Clinically available near-infrared spectroscopy (NIRS) devices use two to five wavelengths of light to measure the relative amounts of oxyhemoglobin and deoxyhemoglobin in tissue to determine tissue hemoglobin oxygen saturation (StO2). In addition to StO2, broadband NIRS devices (using hundreds of wavelengths of light) may be able to measure the oxidation state of mitochondrial cytochrome aa3 (Cytox) which reflects the subcellular energetic state. We hypothesize that broadband NIRS devices can measure Cytox independent of changes in hemoglobin saturation...
December 22, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27986837/greater-v%C3%AB-o2peak-is-correlated-with-greater-skeletal-muscle-deoxygenation-amplitude-and-hemoglobin-concentration-within-individual-muscles-during-ramp-incremental-cycle-exercise
#6
Dai Okushima, David C Poole, Thomas J Barstow, Harry B Rossiter, Narihiko Kondo, T Scott Bowen, Tatsuro Amano, Shunsaku Koga
It is axiomatic that greater aerobic fitness (V˙O2peak) derives from enhanced perfusive and diffusive O2 conductances across active muscles. However, it remains unknown how these conductances might be reflected by regional differences in fractional O2 extraction (i.e., deoxy [Hb+Mb] and tissue O2 saturation [StO2]) and diffusive O2 potential (i.e., total[Hb+Mb]) among muscles spatially heterogeneous in blood flow, fiber type, and recruitment (vastus lateralis, VL; rectus femoris, RF). Using quantitative time-resolved near-infrared spectroscopy during ramp cycling in 24 young participants (V˙O2peak range: ~37...
December 2016: Physiological Reports
https://www.readbyqxmd.com/read/27983541/effect-of-increasing-mean-arterial-blood-pressure-on-microcirculation-in-patients-with-cardiogenic-shock-supported-by-extracorporeal-membrane-oxygenation
#7
Zhongtao Du, Zaishen Jia, Jinhong Wang, Zhichen Xing, Chunjing Jiang, Bo Xu, Xiaofang Yang, Feng Yang, Na Miao, Jialin Xing, Hong Wang, Ming Jia, Xiaotong Hou
BACKGROUND: Little is known about the effect of mean arterial blood pressure (MAP) augmentation on the microcirculation in cardiogenic-shock patients with peripheral veno-arterial extracorporeal membrane oxygenation (ECMO) support. We investigated the effect of increasing MAP on the microcirculation in cardiogenic-shock patients with ECMO support. METHODS: A single-center prospective observational study under taken in ICU patients undergoing ECMO support for post-cardiotomy cardiogenic shock was carried out...
December 14, 2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27932292/graduated-compression-stockings-does-not-decrease-walking-capacity-and-muscle-oxygen-saturation-during-six-minute-walk-test-in-intermittent-claudication-patients
#8
Bruno Remígio Cavalcante, Raphael Mendes Ritti-Dias, Antônio Henrique Germano Soares, Wagner Jorge Ribeiro Domingues, Glauco Fernandes Saes, Flávio Henrique Duarte, Aline de Paula da Cruz, Nelson Wolosker, Pedro Puech-Leão, Gabriel Grizzo Cucato, Antonio Eduardo Zerati
BACKGROUND: We analyze the effects of graduated compression stoking (GCS) on walking capacity and oxygen saturation in intermittent claudication (IC) patients. METHODS: Eighteen patients with IC performed the six-minute walking test in two conditions in random order: GCS or placebo sock. Onset claudication distance and total walking distance were obtained. The calf muscle oxygen saturation was continuously monitored before, during and after six-minute walk test...
December 5, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27904454/red-blood-cell-transfusion-and-skeletal-muscle-tissue-oxygenation-in-anaemic-haematologic-outpatients
#9
Matej Podbregar, Ana Ursula Gavric, Eva Podbregar, Hugon Mozina, Sebastian Stefanovic
BACKGROUND: Stored red blood cells (RBCs) accumulate biochemical and biophysical changes, known as storage lesion. The aim of this study was to re-challenge current data that anaemia in chronically anaemic haematology patients is not associated with low skeletal muscle tissue oxygen (StO2), and that RBC storage age does not influence the tissue response after ischaemic provocation, using near-infrared spectroscopy. PATIENTS AND METHODS: Twenty-four chronic anaemic haematology patients were included...
December 1, 2016: Radiology and Oncology
https://www.readbyqxmd.com/read/27895999/quantifying-the-effect-of-adipose-tissue-in-muscle-oximetry-by-near-infrared-spectroscopy
#10
Nassim Nasseri, Stefan Kleiser, Daniel Ostojic, Tanja Karen, Martin Wolf
Change of muscle tissue oxygen saturation (StO2), due to exercise, measured by near infrared spectroscopy (NIRS) is known to be lower for subjects with higher adipose tissue thickness. This is most likely not physiological but caused by the superficial fat and adipose tissue. In this paper we assessed, in vitro, the influence of adipose tissue thickness on muscle StO2, measured by NIRS oximeters. We measured StO2 of a liquid phantom by 3 continuous wave (CW) oximeters (Sensmart Model X-100 Universal Oximetry System, INVOS 5100C, and OxyPrem v1...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27878503/evaluation-of-different-near-infrared-spectroscopy-technologies-for-assessment-of-tissue-oxygen-saturation-during-a-vascular-occlusion-test
#11
Kevin Steenhaut, Koen Lapage, Thierry Bové, Stefan De Hert, Annelies Moerman
An increasing number of NIRS devices are used to provide measurements of peripheral tissue oxygen saturation (StO2). The aim of the present study is to test the hypothesis that despite technological differences between devices, similar trend values will be obtained during a vascular occlusion test. The devices compared are NIRO-200NX, which measures StO2 and oxyhemoglobin by spatially resolved spectroscopy and the Beer-Lambert law, respectively, and INVOS 5100C and Foresight Elite, which both measure StO2 with the Beer-Lambert law, enhanced with the spatial resolution technique...
November 22, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27862468/response-to-letter-from-tremblay-king-near-infrared-spectroscopy-can-it-measure-conduit-artery-endothelial-function
#12
LETTER
Kaitlin M McLay, Federico Y Fontana, Josh P Nederveen, Donald H Paterson, Silvia Pogliaghi, Juan M Murias
No abstract text is available yet for this article.
January 1, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/27826654/physiological-responses-to-interval-endurance-exercise-at-different-levels-of-blood-flow-restriction
#13
Rogério B Corvino, Harry B Rossiter, Thiago Loch, Jéssica C Martins, Fabrizio Caputo
PURPOSE: We aimed to identify a blood flow restriction (BFR) endurance exercise protocol that would both maximize cardiopulmonary and metabolic strain, and minimize the perception of effort. METHODS: Twelve healthy males (23 ± 2 years, 75 ± 7 kg) performed five different exercise protocols in randomized order: HI, high-intensity exercise starting at 105% of the incremental peak power (P peak); I-BFR30, intermittent BFR at 30% P peak; C-BFR30, continuous BFR at 30% P peak; CON30, control exercise without BFR at 30% P peak; I-BFR0, intermittent BFR during unloaded exercise...
November 8, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27743403/blood-oxygenation-of-masseter-muscle-during-sustained-elevated-muscle-activity-in-healthy-participants
#14
S Suzuki, E E Castrillon, T Arima, Y Kitagawa, P Svensson
Myofascial pain associated with temporomandibular disorders has often been linked to pathological muscle hyperactivity. As a result, localised disturbances of intramuscular blood flow could lead to a lower level of oxygen distribution, hypoxia and microcirculatory changes. To assess haemodynamic changes in the masseter muscle during sustained elevated muscle activity (SEMA). Sixteen healthy participants performed thirty 1-min bouts of SEMA with intervals of 1-min 'rest' periods between the bouts on a bite force transducer device...
December 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27716370/near-infrared-spectroscopy-for-assessing-tissue-oxygenation-and-microvascular-reactivity-in-critically-ill-patients-a-prospective-observational-study
#15
Abele Donati, Elisa Damiani, Roberta Domizi, Claudia Scorcella, Andrea Carsetti, Stefania Tondi, Valentina Monaldi, Erica Adrario, Rocco Romano, Paolo Pelaia, Mervyn Singer
BACKGROUND: Impaired microcirculatory perfusion and tissue oxygenation during critical illness are associated with adverse outcome. The aim of this study was to detect alterations in tissue oxygenation or microvascular reactivity and their ability to predict outcome in critically ill patients using thenar near-infrared spectroscopy (NIRS) with a vascular occlusion test (VOT). METHODS: Prospective observational study in critically ill adults admitted to a 12-bed intensive care unit (ICU) of a University Hospital...
October 1, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27702880/imaging-of-brain-oxygenation-with-magnetic-resonance-imaging-a-validation-with-positron-emission-tomography-in-the-healthy-and-tumoural-brain
#16
Samuel Valable, Aurélien Corroyer-Dulmont, Ararat Chakhoyan, Lucile Durand, Jérôme Toutain, Didier Divoux, Louisa Barré, Eric T MacKenzie, Edwige Petit, Myriam Bernaudin, Omar Touzani, Emmanuel L Barbier
The partial pressure in oxygen remains challenging to map in the brain. Two main strategies exist to obtain surrogate measures of tissue oxygenation: the tissue saturation studied by magnetic resonance imaging (StO2-MRI) and the identification of hypoxia by a positron emission tomography (PET) biomarker with 3-[(18)F]fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([(18)F]-FMISO) as the leading radiopharmaceutical. Nonetheless, a formal validation of StO2-MRI against FMISO-PET has not been performed. The objective of our studies was to compare the two approaches in (a) the normal rat brain when the rats were submitted to hypoxemia; (b) animals implanted with four tumour types differentiated by their oxygenation...
October 4, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27663858/can-transcutaneous-near-infrared-spectroscopy-detect-severe-hepatic-ischemia-a-juvenile-porcine-model
#17
Justin J Skowno, Jonathan S Karpelowsky, Nicola R Watts, David G Little
BACKGROUND: Vascular complications following pediatric liver transplantation occur in 8-10% of cases, and no continuous, non-invasive monitoring for this problem exists. Near infrared spectroscopy (NIRS) allows non-invasive, continuous, transcutaneous assessment of hemoglobin oxygenation (StO2 ) 1-4 cm below the skin surface. AIMS: We hypothesized that transcutaneous NIRS would be able to detect severe hepatic ischemia, and tested this in an animal model using 15-20 kg and 5-7 kg juvenile pigs...
December 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27644435/intraoperative-patterns-of-gastric-microperfusion-during-laparoscopic-sleeve-gastrectomy
#18
Tarik Delko, Henry Hoffmann, Marko Kraljevic, Raoul A Droeser, Lincoln Rothwell, Daniel Oertli, Urs Zingg
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has become a very popular surgical treatment for the treatment of morbidly obese patients. Staple line leaks are the major cause of severe morbidity. Reasons for leaks might be hyperpressure (mechanical theory) or hypoperfusion (vascular theory) of the narrow gastric tube. This study assessed microperfusion patterns of the stomach during LSG using visible light spectroscopy (VLS), a method to measure tissue oxygenation (saturated O2 (StO2))...
September 19, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27614555/monitoring-of-foot-oxygenation-with-near-infrared-spectroscopy-in-patients-with-critical-limb-ischemia-undergoing-percutaneous-transluminal-angioplasty-a-pilot-study
#19
R P E Boezeman, B P Becx, D A F van den Heuvel, Ç Ünlü, J A Vos, J P P M de Vries
OBJECTIVE: Near-infrared spectroscopy (NIRS) non-invasively determines tissue oxygen saturation (Sto2) in muscle tissue. Its application to monitor real time hemodynamic changes during percutaneous transluminal angioplasty (PTA) and Sto2 changes in feet 4 weeks after PTA was evaluated. METHODS: This study included 14 patients with critical limb ischemia (CLI, six patients Rutherford classification Stage IV, two patients Stage V, and six patients Stage VI). In patients with arterial ulcers, NIRS optodes were placed near the ulcer of the diseased foot (Optode 1), and at the same spot at the contralateral foot (Optode 2)...
November 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27542109/tissue-monitoring-with-three-wavelength-light-emitting-diode-based-near-infrared-spectroscopy
#20
Jonathon Bryce Olenczak, Daniel Murariu, Keita Ikeda, Robert H Thiele, Chris A Campbell
Background Flap monitoring with near-infrared spectroscopy (NIRS) facilitates early detection of vascular compromise. However, standard NIRS devices that employ two wavelengths of light to assess tissue oxygenation (StO2) are susceptible to artifact from background noise and demonstrate significant variability in the clinical setting. As the number of wavelengths detected by a NIRS device is increased, the precision of StO2 measurements can be improved and additional chromophores other than oxyhemoglobin and deoxyhemoglobin can be measured...
November 2016: Journal of Reconstructive Microsurgery
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