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https://www.readbyqxmd.com/read/28445802/nmnat-it-s-an-nad-synthase%C3%A2-it-s-a-chaperone%C3%A2-it-s-a-neuroprotector
#1
REVIEW
Jennifer M Brazill, Chong Li, Yi Zhu, R Grace Zhai
Nicotinamide mononucleotide adenylyl transferases (NMNATs) are a family of highly conserved proteins indispensable for cellular homeostasis. NMNATs are classically known for their enzymatic function of catalyzing NAD(+) synthesis, but also have gained a reputation as essential neuronal maintenance factors. NMNAT deficiency has been associated with various human diseases with pronounced consequences on neural tissues, underscoring the importance of the neuronal maintenance and protective roles of these proteins...
April 23, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28445624/the-role-of-publicly-funded-family-planning-sites-in-health-insurance-enrollment
#2
Jennifer Yarger, Sara Daniel, M Antonia Biggs, Jan Malvin, Claire D Brindis
CONTEXT: Publicly funded family planning providers are well positioned to help uninsured individuals learn about health insurance coverage options and effectively navigate the enrollment process. Understanding how these providers are engaged in enrollment assistance and the challenges they face in providing assistance is important for maximizing their role in health insurance outreach and enrollment. METHODS: In 2014, some 684 sites participating in California's family planning program were surveyed about their involvement in helping clients enroll in health insurance...
April 26, 2017: Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28445591/screening-endoscopy-finds-high-prevalence-of-helicobacter-pylori-and-intestinal-metaplasia-in-korean-american-with-limited-access-to-health-care
#3
Yanghee Woo, Carolyn E Behrendt, Garrick Trapp, Jae Geun Hyun, Tamas Gonda, Yuman Fong, Timothy Wang
BACKGROUND: Gastric cancer (GC) is the leading cause of cancer death among Korean Americans. Prevention and early detection is improved by screening. METHODS: Between September 2013 and March 2015, ethnic Koreans age 40 or older without history or symptoms of GC and without upper endoscopy (UE) during previous 3 years were enrolled. Participants were offered screening with GC risk assessment followed by UE with biopsies. RESULTS: Risk assessment was provided to 146 participants (age 55...
April 26, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28445171/identification-of-depressive-signs-in-patients-and-their-family-members-during-ipad-based-audiovisual-sessions
#4
Carol E Smith, Marilyn Werkowitch, Donna Macan Yadrich, Noreen Thompson, Eve-Lynn Nelson
Home parenteral nutrition requires a daily life-sustaining intravenous infusion over 12 hours. The daily intravenous infusion home care procedures are stringent, time-consuming tasks for patients and family caregivers who often experience depression. The purposes of this study were (1) to assess home parenteral nutrition patients and caregivers for depression and (2) to assess whether depressive signs can be seen during audiovisual discussion sessions using an Apple iPad Mini. In a clinical trial (N = 126), a subsample of 21 participants (16...
April 25, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/28444957/epidemiology-of-endometriosis-a-large-population-based-database-study-in-a-2-million-member-health-care-provider
#5
Vered H Eisenberg, Clara Weil, Gabriel Chodick, Varda Shalev
OBJECTIVE: Endometriosis constitutes a significant burden on the quality of life of women, their families, and health systems. The objective of this study is to describe the real-world epidemiology of endometriosis in an unselected low-risk population in Israel. DESIGN: Retrospective population-based study. SETTING AND POPULATION: The computerized databases of Maccabi Healthcare Services (MHS), a 2-million-member healthcare provider representing a quarter of the Israeli population...
April 26, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28444902/trajectory-of-social-inequalities-in-the-treatment-of-dental-caries-among-preschool-children-in-japan
#6
Jun Aida, Yusuke Matsuyama, Takahiro Tabuchi, Yuko Komazaki, Toru Tsuboya, Tsuguhiko Kato, Ken Osaka, Takeo Fujiwara
OBJECTIVES: The longitudinal trend of dental health inequalities among preschool children has not been described. In this study, we aimed to measure the trajectory of both relative and absolute inequalities in caries treatment among preschool children in Japan. METHODS: We used data from the Longitudinal Survey of Babies in the 21st Century (LSB21), which is an ongoing national representative longitudinal study. The target population was families residing in Japan with newborn baby/babies born between 10 January and 17 January or 10 July and 17 July 2001...
April 26, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28444652/-establishment-of-specialized-pediatric-palliative-home-care-in-the-medical-valley-of-the-european-metropolitan-area-nuremberg
#7
Steven Hébert, Chara Gravou-Apostolatou, Wolfgang Rascher
Background As part of the 2007 health reform in Germany the structure of outpatient palliative care for children and adolescents was adopted for the first time and then implemented in Erlangen-Nuremberg in 2009. Methods The introduction of Pediatric Palliative Home Care (PPHC) at the Hospital for Children and Adolescents at the University of Erlangen-Nuremberg was retrospectively analyzed between the years 2009 to 2014. Referring medical records (paper-based and electronic) were evaluated systematically. Results Considering 69 patients within this study, 44 (63...
March 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28444629/stress-measured-by-allostatic-load-score-varies-by-reason-for-immigration-the-africans-in-america-study
#8
Jean N Utumatwishima, Rafeal L Baker, Brianna A Bingham, Stephanie T Chung, David Berrigan, Anne E Sumner
OBJECTIVE: Reason for immigration as a biological stress has not been studied in Africans. Our goal was to determine in African immigrants, if biological stress measured by allostatic load score (ALS) varies by reason for immigration. METHODS: Using an ALS which had been previously developed with the National Health and Nutrition Examination Survey (NHANES) data to assess stress due to racism and nativity, ALS was calculated in 85 African immigrants (67% male, age 42 ± 10 years)...
April 25, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28444574/a-randomized-controlled-trial-of-the-effectiveness-of-a-psychoeducational-intervention-on-family-caregivers-of-patients-with-mental-disorders
#9
Viviane Tabeleão, Elaine Tomasi, Luciana de Avila Quevedo
The present study aimed to investigate the effectiveness of a psychoeducational intervention on caregivers of patients assisted by the Center for Psychosocial Health Care (CPHC) focusing on the patient's psychopathology. This was a randomized clinical trial with 130 caregivers with higher mean burden scores assessed using the Zarit Burden Interview Scale (ZBI) (66 caregivers in the intervention group and 64 in the control group). The intervention included six home visits of psychoeducational interventions according to each mental disorder identified in the CPHC records...
April 25, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28444518/video-based-approach-to-engaging-parents-into-a-preventive-parenting-intervention-for-divorcing-families-results-of-a-randomized-controlled-trial
#10
Emily B Winslow, Sanford Braver, Robert Cialdini, Irwin Sandler, Jennifer Betkowski, Jenn-Yun Tein, Liza Hita, Mona Bapat, Lorey Wheeler, Monique Lopez
The public health impact of evidence-based, preventive parenting interventions has been severely constrained by low rates of participation when interventions are delivered under natural conditions. It is critical that prevention scientists develop effective and feasible parent engagement methods. This study tested video-based methods for engaging parents into an evidence-based program for divorcing parents. Three alternative versions of a video were created to test the incremental effectiveness of different theory-based engagement strategies based on social influence and health behavior models...
April 25, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28444349/adult-children-s-education-and-physiological-dysregulation-among-older-parents
#11
Chioun Lee
Objectives: Despite growing awareness that children's education benefits the health of older parents, the underlying mechanisms of this relationship are not well-understood. We investigated (a) the associations between children's education and biological functioning of parents, (b) psychosocial and behavioral factors that explain the associations, and (c) gendered patterns in the associations. Methods: Using longitudinal data from a nationally representative sample of older Taiwanese, we performed mediation analysis of the association between adult children's education and physiological dysregulation of their parents...
April 21, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28444187/modelling-the-cost-effectiveness-pcsk9-inhibitors-vs-ezetimibe-through-ldl-c-reductions-in-a-norwegian-setting
#12
Max Korman, Torbjørn Wisløff
Aims: Despite the success of statins, there remains unmet clinical need in cardiovascular disease (CVD) prevention. New proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors reduce low-density lipoprotein cholesterol (LDL-C) by 55-65%. Two PCSK9 inhibitors, evolocumab and alirocumab, were approved for use in Norway but not yet for reimbursement through public national insurance. We aim to explore the cost-effectiveness of these compared to available treatments in a Norwegian setting...
April 21, 2017: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/28444050/ambulatory-municipal-regulation-of-the-unified-health-system-services-in-rio-de-janeiro-advances-limitations-and-challenges
#13
Luiz Felipe Pinto, Daniel Soranz, Mariana Tomasi Scardua, Iandara de Moura Silva
Federalism is basis of the Republic of Brazil which is made up of the union of states, municipalities and the Federal District, with the basic principle of political and administrative decentralization in all political, economic and social relations. In the health sector, the primary health care provider should be able to integrate all care that the patient receives through the coordination of health services. This article aims to evaluate the results of referrals for consultations and outpatient examinations in primary health care in the municipality of Rio de Janeiro, highlighting the advances, limitations and challenges for management at the local level...
April 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28444002/-analysis-of-proximate-determinants-and-impact-of-type-of-employment-on-fertility-in-peruvian-women
#14
Yordanis Enríquez-Canto, Katherine Ortiz-Romaní, Yonathan Ortiz-Montalvo
Objective: To estimate the predictive capacity of proximate determinants and type of employment with respect to reduced fertility in Peruvian women of childbearing age. Methods: Secondary analysis of Peru's Demographic and Family Health Survey (ENDES) for 2014. The sample consisted of 20 396 women aged 15 to 49 years who had been sexually active during the four-week period immediately before the interview. The dependent variable was the total number of live births, and the main independent variables were type of employment, ideal number of offspring, highest educational level attained, and wealth quintile...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28443995/quality-of-life-of-people-living-with-hiv-aids-temporal-socio-demographic-and-perceived-health-relationship
#15
Rodrigo Leite Hipolito, Denize Cristina de Oliveira, Tadeu Lessa da Costa, Sergio Corrêa Marques, Eliane Ramos Pereira, Antonio Marcos Tosoli Gomes
OBJECTIVE: to analyze the quality of life of people living with HIV/AIDS and its relationship with sociodemographic variables, health satisfaction and time since diagnosis. METHOD: quantitative, cross-sectional study with a sample of 100 HIV positive people monitored in a specialized service in southeastern Brazil. Sociodemographic and health forms were applied, followed by the WHOQOL-HIV BREF, a short form instrument validated to evaluate the quality of life. Descriptive and inferential statistical analysis was performed...
April 20, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28443993/work-accidents-and-self-esteem-of-nursing-professional-in-hospital-settings
#16
Sérgio Valverde Marques Dos Santos, Flávia Ribeiro Martins Macedo, Luiz Almeida da Silva, Zelia Marilda Rodrigues Resck, Denismar Alves Nogueira, Fábio de Souza Terra
OBJECTIVE: to analyze the occurrence of work accidents and the self-esteem of nurses in hospitals of a municipality of Minas Gerais. METHOD: descriptive-analytical and cross-sectional study developed with 393 nursing professionals from three hospitals of a municipality in southern Minas Gerais. The Rosenberg Self-Esteem Scale and a questionnaire to characterize the population and work accidents were used for data collection. Data analysis was performed using Person's chi-squared test, Fisher's exact test, Cronbach's alpha, odds ratio and logistic regression...
April 20, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28443972/online-information-as-support-to-the-families-of-children-and-adolescents-with-chronic-disease
#17
Verônica de Azevedo Mazza, Vanessa Ferreira de Lima, Ana Karoline da Silva Carvalho, Gisele Weissheimer, Larissa Gramazio Soares
Objective: To describe the use of online information as support to families of children and adolescents with chronic disease. Methods: This is an integrative review conducted in August 2015, with an online search in the following databases: PubMed, Biblioteca Virtual em Saúde, Cumulative Index to Nursing & Allied Health Literature, and Science Direct. Results: Twelve studies were selected from the 293 studies found in the databases. After analysis, the following two categories emerged: Potentialities of the use of online information by families of children and adolescents with chronic disease, and Weaknesses of the use of online information by families of children and adolescents with chronic disease...
April 20, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28443699/the-experiences-of-parents-of-pediatric-patients-with-acute-lymphoblastic-leukemia-2-months-after-completion-of-treatment
#18
Barbara Muskat, Heather Jones, Sonia Lucchetta, Wendy Shama, Sue Zupanec, Andrea Greenblatt
Diagnosis and treatment of childhood acute lymphoblastic leukemia (ALL) can be a highly stressful time for the entire family. While completion of treatment may bring relief to some families, it may also bring about additional anxieties and fear. The primary objective of this article is to present an analysis of the experiences, emotional states, and support needs of parents of pediatric cancer patients 2 months after treatment completion for ALL. Using a qualitative interpretive description approach, transcripts from interviews with 17 parents from the leukemia/lymphoma program of a large urban pediatric cancer center were analyzed using N-Vivo 10 data analysis software...
April 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28443574/parents-attitudes-and-adherence-to-unintentional-injury-prevention-measures-in-ankara-turkey
#19
Tolga İnce, Songül Yalçın, Kadriye Yurdakök
BACKGROUND: Childhood unintentional injuries are being perceived as a leading public health issue since they are one of the preventable causes of pediatric mortality and morbidity. Whether and how parental factors related to childhood injury are searched insufficiently. So, understanding what parents do to prevent injuries, how well these prevention strategies work, and what encourages these actions is essential to decrease unintentional injury risk and to develop effective injury prevention strategies...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28443367/preventing-risky-behaviours-among-young-adolescents-in-eastern-democratic-republic-of-congo-a-qualitative-study
#20
Anjalee Kohli, Mitima Mpanano Remy, Arsene Kajabika Binkurhorhwa, Clovis Murhula Mitima, Alfred Bacikenge Mirindi, Nadine Bufole Mwinja, Jean Heri Banyewesize, Gisele Mushengezi Ntakwinja, Nancy A Perrin, Nancy Glass
This qualitative study explores and describes adolescent risk behaviours, specifically consumption of alcohol and use of violence; the perceived consequences of these behaviours on future well-being and relationships; and collaboratively identifies the essential components of a prevention intervention for risk behaviours (alcohol use, violence) among young adolescents while strengthening the protective individual and relationship factors in post-conflict Democratic Republic of Congo. One-on-one in-depth interviews were conducted with 28 male and female youth, 20 parents/guardians and 20 stakeholders in three rural villages of South Kivu Province...
April 26, 2017: Global Public Health
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