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https://www.readbyqxmd.com/read/28547877/comparative-study-of-osteogenic-activity-of-multilayers-made-of-synthetic-and-biogenic-polyelectrolytes
#1
Deepak Guduru, Marcus S Niepel, Cristina Gonzalez-Garcia, Manuel Salmeron-Sanchez, Thomas Groth
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the osteogenic activity of PEM with human osteosarcoma MG-63 cells in a comparative manner. Formation of PEM is achieved with biogenic PEL fibrinogen (FBG) and poly-l-lysine (PLL) as well as biotinylated chondroitin sulfate (BCS) and avidin (AVI), while poly(allylamine hydrochloride) (PAH) and polystyrene sulfonate (PSS) represent a fully synthetic PEM used as a reference system here...
May 26, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28547844/metal-organic-compound-branched-mos2-for-achieving-high-performance-perovskite-solar-cells
#2
Ruina Dai, Yangyang Wang, Jie Wang, Xianyu Deng
MoS2 as a graphene-like 2D material shows a large potential to replace even overcome graphene in various important applications due to its perfect properties of electrical, optical, frictional, and tunable band gap. However, low solubility in the most of common solvents makes it difficult to prepare via a simple solution process. Here we introduce a metalorganic compound to modify MoS2. Phenyl acetylene silver (PAS) functionalized MoS2 compound is easily dispersed in the solvent of DMF and water. A conductive polymer PEDOT: PSS blend with the MoS2 leads to a significant enhancement of the performance of planar heterojunction perovskite solar cells...
May 25, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28546741/sj%C3%A3-gren-s-syndrome-is-associated-with-negatively-variable-impacts-on-domains-of-health-related-quality-of-life-evidence-from-short-form-36-questionnaire-and-a-meta-analysis
#3
REVIEW
Qiuxiang Zhang, Xulin Wang, Haoyang Chen, Biyu Shen
PURPOSE: The purpose of this article was to systematically review the literature to identify the impact of primary Sjögren's syndrome (pSS) on specific health-related quality of life (HRQoL) domains. METHODS: A meta-analysis was performed, and the related articles were searched in Medline, Embase, Cochrane Library, China National Knowledge Infrastructure, China Biology Medicine, and Web of Science databases and in reference lists of articles and systematic reviews...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28540103/correlation-between-kind-of-delivery-and-posttraumatic-stress-disorder
#4
Z Mahmoodi, M Dolatian, Z Shaban, J Shams, H Alavi-Majd, A Mirabzadeh
BACKGROUND: Posttraumatic stress disorder (PTSD) is a very common mental condition and a unique anxiety disorder. AIM: The present study tried to examine the correlation between kind of delivery and PTSD. SUBJECTS AND METHODS: This prospective study evaluated 240 Iranian female residents of Tehran, Iran, during the third trimester of their pregnancy and 6-8 weeks after labor. Data were collected using the customized screening form, the Symptom Checklist-90, PTSD Symptom Scale (PSS), and Social Support Questionnaire...
November 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28535890/impacts-of-social-support-on-symptoms-in-brazilian-women-with-fibromyalgia
#5
Rodrigo Pegado de Abreu Freitas, Sandra Cristina de Andrade, Maria Helena Constantino Spyrides, Maria Thereza Albuquerque Barbosa Cabral Micussi, Maria Bernardete Cordeiro de Sousa
We aimed to assess the impact of social support on symptoms in Brazilian women with FM. An observational, descriptive study enrolling 66 women who met the 1990 American College of Rheumatology (ACR) criteria. Social support was measured by the Social Support Survey (MOS-SSS), functionality was evaluated using the Fibromyalgia Impact Questionnaire (FIQ), depression was assessed using the Beck Depression Inventory (BDI), anxiety was measured using the Hamilton Anxiety Scale (HAS), affectivity was measured by Positive and Negative Affect Schedule (PANAS), and algometry was carried out to record pressure pain threshold (PPth) and tolerance (PPTo) at 18 points recommended by the ACR...
May 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28535365/leukocyte-telomere-length-in-postmenopausal-women
#6
Holly J Jones, Susan L Janson, Kathryn A Lee
OBJECTIVE: To compare leukocyte telomere length (LTL) by race and describe demographic, health, and psychosocial factors associated with LTL in postmenopausal women. DESIGN: Descriptive study with comparative analyses and correlations. SETTING: Data were collected at the University of California-San Francisco, San Francisco Clinical and Translational Science Institute. PARTICIPANTS: Thirty-nine African American and White postmenopausal women between 58 and 65 years of age (mean age = 61...
May 20, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28532233/updates-on-sj%C3%A3-gren-s-syndrome-from-proteomics-to-protein-biomarkers
#7
Chiara Baldini, Antonella Cecchettini, Alessia Gallo, Stefano Bombardieri
Primary Sjögren's syndrome (pSS) is a complex heterogeneous autoimmune disorder, typically affecting exocrine glands. Recently, a great interest has arisen in searching for novel biomarkers able to improve the diagnostic work-up of the disease as well as the general assessment and the prognostic stratification of pSS patients. From this perspective, salivary proteomics has appeared as a promising tool considering that salivary proteins may closely reflect the underlying disease processes in the salivary glands...
May 26, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/28532196/fetal-and-neonatal-involvement-in-maternal-rheumatologic-disease
#8
Shigeo Iijima
A pregnancy complicated with rheumatologic diseases can have various influences on the fetus and/or neonate. Maternal systemic lupus erythematosus (SLE) may cause preterm and/or small for gestational age (SGA) delivery and neonatal lupus (NL). Some neonates with NL have congenital heart block (CHB) with increased morbidity and mortality, even requiring pacemakers. Antiphospholipid syndrome may occur with SLE and affect fetal and/or neonatal outcomes. Pregnancy involving primary Sjögren syndrome (pSS) tends to result in preterm delivery and low birthweight infants...
May 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28531350/embedded-metal-electrode-for-organic-inorganic-hybrid-nanowire-solar-cells
#9
Han-Don Um, Deokjae Choi, Ahreum Choi, Ji Hoon Seo, Kwanyong Seo
We demonstrate here an embedded metal electrode for highly efficient organic-inorganic hybrid nanowire solar cells. The electrode proposed here is an effective alternative to the conventional bus and finger electrode which leads to a localized short circuit at a direct Si/metal contact and has a poor collection efficiency due to a nonoptimized electrode design. In our design, an Ag/SiO2 electrode is embedded into a Si substrate while being positioned between Si nanowire (SiNW) arrays underneath poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), facilitating suppressed recombination at the Si/Ag interface and notable improvements in the fabrication reproducibility...
May 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28528162/intervendor-differences-in-the-accuracy%C3%A2-of%C3%A2-detecting-regional-functional%C3%A2-abnormalities-a-report-from-the-eacvi-ase-strain-standardization-task%C3%A2-force
#10
Oana Mirea, Efstathios D Pagourelias, Jurgen Duchenne, Jan Bogaert, James D Thomas, Luigi P Badano, Jens-Uwe Voigt
OBJECTIVES: The purpose of this study was to compare the accuracy of vendor-specific and independent strain analysis tools to detect regional myocardial function abnormality in a clinical setting. BACKGROUND: Speckle tracking echocardiography has been considered a promising tool for the quantitative assessment of regional myocardial function. However, the potential differences among speckle tracking software with regard to their accuracy in identifying regional abnormality has not been studied extensively...
May 11, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528128/comparison-of-the-diagnostic-value-of-four-scoring-systems-in-primary-sj%C3%A3-gren-s-syndrome-patients
#11
Xuan Qi, Chao Sun, Yu Tian, Yuxiang Han, Chenxing Peng, Hongtao Jin, Lixia Gao
PURPOSE: We attempted to evaluate the diagnostic value of different salivary gland ultrasonography (SGUS) scoring systems for primary sjögren's syndrome (pSS). METHODS: Total 134 patients with pSS and 109 non-SS sicca controls were included in our study. All the cases were evaluated by four scoring systems (such as 0-16 SGUS, 0-3 SGUS, Parotid glands and Submandibular salivary glands scoring system). The receiver operating characteristic (ROC) analysis was performed for the four scoring systems...
May 17, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28526863/potential-of-pedot-pss-as-a-hole-selective-front-contact-for-silicon-heterojunction-solar-cells
#12
Sara Jäckle, Martin Liebhaber, Clemens Gersmann, Mathias Mews, Klaus Jäger, Silke Christiansen, Klaus Lips
We show that the highly conductive polymer poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) can successfully be applied as a hole selective front contact in silicon heterojunction (SHJ) solar cells. In combination with a superior electron selective heterojunction back contact based on amorphous silicon (a-Si), mono-crystalline n-type silicon (c-Si) solar cells reach power conversion efficiencies up to 14.8% and high open-circuit voltages exceeding 660 mV. Since in the PEDOT:PSS/c-Si/a-Si solar cell the inferior hybrid junction is determining the electrical device performance we are capable of assessing the recombination velocity (v I ) at the PEDOT:PSS/c-Si interface...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526615/lung-inflammation-after-bleomycin-treatment-in-mice-selection-of-an-accurate-normalization-strategy-for-gene-expression-analysis-in-an-ex-vivo-and-in-vitro-model
#13
Veronica Della Latta, Manuela Cabiati, Silvia Burchielli, Giada Frenzilli, Margherita Bernardeschi, Antonella Cecchettini, Federica Viglione, Maria-Aurora Morales, Silvia Del Ry
Pulmonary fibrosis (PF) is the most common and aggressive interstitial lung disease, characterized by a patchy development of fibrosis leading to progressive destruction of the normal lung architecture which is preceded by an inflammatory process. Gene expression studies are important to understand the development of PF but the accuracy and reproducibility of Real-Time PCR depend on appropriate normalization strategies. This study aimed to analyze the expression variability of eight commonly used reference genes during the initial inflammatory phase of bleomycin-induced PF in a mouse model and to verify whether the selected reference genes could be applied to an in-vitro model of BLM-treated primary murine lung fibroblasts...
May 16, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28526333/systemic-manifestations-of-primary-sj%C3%A3-gren-s-syndrome-in-the-nod-b10sn-h2-b-j-mouse-model
#14
Jeremy Kiripolsky, Long Shen, Yichen Liang, Alisa Li, Lakshmanan Suresh, Yun Lian, Quan-Zhen Li, Daniel P Gaile, Jill M Kramer
Animal models that recapitulate human disease are crucial for the study of Sjögren's Syndrome (SS). While several SS mouse models exist, there are few primary SS (pSS) models that mimic systemic disease manifestations seen in humans. Similar to pSS patients, NOD.B10Sn-H2(b)/J (NOD.B10) mice develop exocrine gland disease and anti-nuclear autoantibodies. However, the disease kinetics and spectrum of extra-glandular disease remain poorly characterized in this model. Our objective was to characterize local and systemic SS manifestations in depth in NOD...
May 16, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/28523914/polymerizable-supramolecular-approach-to-highly-conductive-pedot-pss-patterns
#15
Taegeun Kim, Suryong Ha, Hyosung Choi, Kyungchan Uh, Umesha Kundapur, Sumin Park, Chan Woo Lee, Sang-Hwa Lee, Jaeyong Kim, Jong-Man Kim
Owing to its high conductivity, solution processability, mechanical flexibility and transparency, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) has been extensively explored for use in functional devices including solar cells, sensors, light emitting diodes and supercapacitors. The ability to fabricate patterned PEDOT:PSS on a solid substrate is of significant importance in order to develop practical applications of this conducting polymer. Herein we describe a new approach to obtain PEDOT:PSS patterns that is based on a polymerizable supramolecular concept...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28520199/economic-evaluation-of-strategies-for-restarting-anticoagulation-therapy-after-a-first-event-of-unprovoked-venous-thromboembolism
#16
M Monahan, J Ensor, D Moore, D Fitzmaurice, S Jowett
BACKGROUND: Following at least three months of anticoagulation therapy after a first unprovoked Venous Thromboembolism (VTE), there is uncertainty about the duration of therapy. Further anticoagulation therapy reduces the risk of having a potentially fatal recurrent VTE but at the expense of a higher risk of bleeding which can also be fatal. OBJECTIVE: An economic evaluation sought to estimate the long-term cost-effectiveness of using a decision rule for restarting anticoagulation therapy versus no extension of therapy in patients based on their risk of a further unprovoked VTE...
May 18, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28513994/ultrahigh-conductivity-polymer-hydrogels-with-arbitrary-structures
#17
Bowen Yao, Haiyan Wang, Qinqin Zhou, Mingmao Wu, Miao Zhang, Chun Li, Gaoquan Shi
A poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) hydrogel is prepared by thermal treatment of a commercial PEDOT:PSS (PH1000) suspension in 0.1 mol L(-1) sulfuric acid followed by partially removing its PSS component with concentrated sulfuric acid. This hydrogel has a low solid content of 4% (by weight) and an extremely high conductivity of 880 S m(-1) . It can be fabricated into different shapes such as films, fibers, and columns with arbitrary sizes for practical applications. A highly conductive and mechanically strong porous fiber is prepared by drying PEDOT:PSS hydrogel fiber to fabricate a current-collector-free solid-state flexible supercapacitor...
May 17, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28511858/reduced-myocardial-reserve-in-young-x-linked-muscular-dystrophy-mice-diagnosed-by-two-dimensional-strain-analysis-combined-with%C3%A2-stress-echocardiography
#18
Zhenzhou Li, Ying Li, Li Zhang, Xiaoying Zhang, Rebecca Sullivan, Xiaojie Ai, Christopher Szeto, Angela Cai, Longjian Liu, Weidong Xiao, Quanshui Li, Shuping Ge, Xiongwen Chen
BACKGROUND: Early, sensitive, and reproducible evaluation of left ventricular function is imperative for the diagnosis of cardiac dysfunction in patients with Duchene muscular dystrophy. The aim of this study was to test the hypothesis that combining two-dimensional strain analysis with catecholamine stress could be a sensitive method for detecting early cardiac dysfunction. METHODS: Mdx (C57BL/10ScSn-Dmdmdx/J, a mouse model of DMD) and control (C57BL/10ScSn) mice were studied with conventional M-mode and high-frequency ultrasound-based two-dimensional speckle-tracking echocardiography using long- and short-axis images of the left ventricle at baseline and after intraperitoneal isoprenaline (ISO) administration (2 μg/g body weight)...
May 13, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28511420/effect-of-intraperitoneal-injection-of-saffron-on-the-treatment-of-experimental-endotoxin-induced-uveitis-in-the-rabbit
#19
Mohammad Reza Talebnejad, Kazem Soltanzadeh, Eghtedari Masoomeh, Masoud Yasemi, Mohammad Reza Khalili, Sherafat Maryam
INTRODUCTION: Saffron with scientific name of "Crocus sativus" from the family "Iridaceae" is a plant without stem and root. Antioxidative and immunomodulatory effects of saffron has been demonstrated in different studies. AIM: To assess the effects of saffron in the treatment on Lipopolysaccharide (LPS) induced uveitis in the rabbit. MATERIALS AND METHODS: Thirty healthy female New Zealand white rabbits were prepared. LPS induced uveitis was confirmed via slit lamp examination 24 hours after intravitreal injection of Salmonella typhimurium LPS endotoxin in the right eye of all rabbits...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511386/assessment-of-disease-severity-and-role-of-cytomegalo-virus-infection-in-patients-with-ulcerative-colitis
#20
Nobin Babu Kalappurayil, Jino Thomas, Baburajan Mankuni, Varghese Thomas
INTRODUCTION: Course of Ulcerative Colitis is characterized by intermittent flares interposed between variable periods of remission. Identification of exacerbating factors and appropriate assessment of disease activity are crucial in deciding the choice of treatment. AIM: To evaluate various clinical, endoscopic and histological parameters in assessing disease activity and to find out various risk factors involved in the exacerbation of ulcerative colitis especially the role of Cytomegalo Virus (CMV) infection...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
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