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https://www.readbyqxmd.com/read/28933756/a-disposable-amperometric-sensor-based-on-high-performance-pedot-pss-ionic-liquid-nanocomposite-thin-film-modified-screen-printed-electrode-for-the-analysis-of-catechol-in-natural-water-samples
#1
Francis D Krampa, Yaw Aniweh, Gordon A Awandare, Prosper Kanyong
A conducting polymer-based composite material of poly(3,4-ethylenedioxythiophene) (PEDOT): poly(4-styrenesulfonate) (PSS) doped with different percentages of a room temperature ionic liquid (IL), 1-ethyl-3-methylimidazolium tetrafluoroborate ([EMIM][BF₄]), was prepared and a very small amount of the composite (2.0 µL) was drop-coated on the working area of a screen-printed carbon electrode (SPCE). The SPCE, modified with PEDOT:PSS/IL composite thin-film, was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), profilometry and sessile contact angle measurements...
July 26, 2017: Sensors
https://www.readbyqxmd.com/read/28933712/volume-load-and-neuromuscular-fatigue-during-an-acute-bout-of-agonist-antagonist-paired-set-vs-traditional-set-training
#2
Gabriel A Paz, Daniel W Robbins, Carlos G de Oliveira, Martim Bottaro, Humberto Miranda
Paz, GA, Robbins, DW, de Oliveira, CG, Bottaro, M, and Miranda, H. Volume load and neuromuscular fatigue during an acute bout of agonist-antagonist paired-set vs. traditional-set training. J Strength Cond Res 31(10): 2777-2784, 2017-The purpose of this study was to investigate the acute effects of performing paired-set (PS) vs. traditional-set (TS) training over 3 consecutive sets, on volume load and electromyographic fatigue parameters of the latissimus dorsi, biceps brachii, pectoralis major, and triceps brachii muscles...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28933131/the-clinical-spectrum-of-primary-sj%C3%A3-gren-s-syndrome-beyond-exocrine-glands
#3
M C Leone, A Alunno, G Cafaro, V Valentini, E Marcucci, E Bartoloni, R Gerli
Although primary Sjögren's syndrome (pSS) is a mild indolent chronic disease mainly characterized by mucosal dryness in the majority of cases, a consistent subgroup of patients display extra-glandular manifestations. Virtually any organs and systems can be affected, leading to a more serious disease prognosis. Therefore, the prompt identification of patients at higher risk of extra-glandular manifestations is necessary to start a thorough follow up and an aggressive treatment. The aim of this review article is to provide an overview of epidemiological, clinical and serological features of extra-glandular manifestations in pSS as well as current knowledge about putative biomarkers useful in clinical practice...
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28931060/isolated-positive-anti-ss-b-autoantibodies-are-not-related-to-clinical-features-of-systemic-autoimmune-diseases-results-from-a-routine-population-survey
#4
Sabine Jardel, Nicole Fabien, Arnaud Hot, Sandra Vukusic, Jacques Tebib, Vincent Cottin, Pascal Sève, Maurice Laville, Alexandre Belot, Isabelle Durieu, Lorna Garnier, Frédéric Coutant, Quitterie Reynaud, Jean Christophe Lega
OBJECTIVE: To assess in clinical practice the frequency and diagnosis associated with the SS-B-positive/SS-A negative autoantibody profile. METHODS: We analyzed a one-year consecutive population of 624 patients referred by clinicians to the immunology laboratory to investigate anti-SS-A and/or anti-SS-B autoantibodies, who were detected using luminex technology. Data were analyzed for patients with isolated anti-SS-B autoantibodies. The clinical characteristics and diagnosis of connective tissue diseases (CTD) were retrieved according to the international criteria...
2017: PloS One
https://www.readbyqxmd.com/read/28930452/electrowetting-on-immersed-conducting-hydrogel
#5
Caroline Duc, Alexis Vlandas, George G Malliaras, Vincent Senez
Conducting polymers demonstrate an interesting ability to change their wettability at ultra-low voltage (<1V). While the conducting hydrogel poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) is increasingly used as an interface with biology partly thanks to its mechanical properties, little is known about the electrical control of its wettability. We rely on the captive bubble technique to study this hydrogel property in relevant conditions (fully immerged) We here report that the wettability variations of PEDOT:PSS are driven by an electrowetting phenomenon in contrast to other conducting polymers which are thought to undergo wettability changes due to oxido-reduction reactions...
September 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28930319/revealing-the-correlation-between-charge-carrier-recombination-and-extraction-in-an-organic-solar-cell-under-varying-illumination-intensity
#6
Abhishek Sharma, Mihirsinh Chauhan, Vishal Bharti, Manoj Kumar, Suresh Chand, Brijesh Tripathi, J P Tiwari
The design and fabrication of better excitonic solar cells are the need of the hour for futuristic energy solutions. This designing needs a better understanding of the charge transport properties of excitonic solar cells. One of the popular methods of understanding the charge transport properties is the analysis of the J-V characteristics of a device through theoretical simulation at varied illumination intensity. Herein, a J-V characteristic of a polymer:fullerene based bulk heterojunction (BHJ) organic solar cells (OSCs) of structure ITO/PEDOT:PSS (∼40 nm)/PTB7:PC71BM (∼100 nm)/Al (∼120 nm) is analyzed using one- and two-diode models at varied illumination intensity in the range of 0...
September 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28928382/functional-effects-of-proinflammatory-factors-present-in-sj%C3%A3-gren-s-syndrome-salivary-microenvironment-in-an-in-vitro-model-of-human-salivary-gland
#7
Mayte Arce-Franco, María Dominguez-Luis, Martina K Pec, Carlos Martínez-Gimeno, Pablo Miranda, Diego Alvarez de la Rosa, Teresa Giraldez, José María García-Verdugo, José David Machado, Federico Díaz-González
Primary Sjögren's syndrome (pSS) is an autoimmune exocrinopathy in which the role that the immune response plays in reducing exocrine gland function, including the glandular microenvironment of cytokines, has not been fully understood. Epithelial cells from biopsies of human parotid gland (HPG) were used to establish a model of human salivary gland in vitro. In this model, the functional consequences of several proinflammatory soluble factors present in the pSS glandular microenvironment were assessed. Stimulation with isoproterenol and calcium produced a significant increase in the basal activity of amylase in the HPG cell supernatants...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28923402/synergistic-chemo-photodynamic-therapy-by-big-small-combo-nanoparticles-sequential-release-system
#8
Li Fan, Saisai Zhao, Xin Jin, Yongsheng Zhang, Chaojun Song, Hong Wu
Chemo-photodynamic combination has been manifested great potential for synergistic cancer therapy. Moreover, the synergistic efficacy could be significantly enhanced by well designed sequential release manner of photosensitizers (PSs). Here we propose a "Big & small combo nanoparticles (NPbig&small)" system for double loading PSs methylene blue (MB) and single absorbing chemotherapeutics drug Gemcitabine hydrochloride (GM(.)HCl). The "grown-in" MB from NPbig&small show two-peak sequential release profile, significantly improve the absorbed chemo therapeutic efficacy of GM(...
September 15, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28923110/development-of-an-arabic-inpatient-satisfaction-survey-application-in-acute-medical-rehabilitation-setting-in-saudi-arabia
#9
Ahmed Aboabat, Hazem Qannam
BACKGROUND: In the management of chronic disease, evidence suggests that satisfied patients exhibit more loyalty to treatment providers and greater adherence to treatment regimens. This is particularly so in the rehabilitation setting. We aimed to develop a reliable and valid Arabic-language survey to objectively measure inpatient satisfaction in medical rehabilitation settings in Saudi Arabia. METHODS: The King Fahad Medical City Rehabilitation Hospital Patient Satisfaction Survey (RH PSS) is a self-administered survey that addresses four domains of rehabilitation care: access, structure, process, and outcomes...
September 18, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28919520/antibodies-against-citrullinated-alpha-enolase-peptides-in-primary-sjogren-s-syndrome
#10
Adrianos Nezos, Ilir Cinoku, Clio P Mavragani, Haralampos M Moutsopoulos
Citrullinated alpha enolase (CEP-1) has been designated as a major antigenic target of antibodies against citrullinated proteins (ACPA) in patients with rheumatoid arthritis (RA). Our aim is to determine the prevalence of anti-CEP-1 in a cohort of ACPA positive (ACPA+) primary Sjogren's syndrome (pSS) patients. Anti-CEP1 titers were determined by ELISA in sera from 15 ACPA+ and 45 ACPA- age/sex matched pSS; 12 ACPA+ RA patients and 30 healthy controls (HC). Increased anti-CEP-1 antibody titers were detected in nine out of the 15 (60%) ACPA+ pSS patients and 5 out of 12 (41...
September 14, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/28916716/deregulation-of-microrna-expression-in-purified-t-and-b-lymphocytes-from-patients-with-primary-sj%C3%A3-gren-s-syndrome
#11
Shu-Fang Wang-Renault, Saida Boudaoud, Gaétane Nocturne, Elodie Roche, Nelly Sigrist, Christian Daviaud, Andreas Bugge Tinggaard, Victor Renault, Jean-François Deleuze, Xavier Mariette, Jörg Tost
OBJECTIVE: MicroRNAs (miRNAs) play an important role in the pathogenesis of autoimmune diseases such as primary Sjögren's syndrome (pSS). This study is the first to investigate miRNA expression patterns in purified T and B lymphocytes from patients with pSS using a high-throughput quantitative PCR (qPCR) approach. METHODS: Two independent cohorts of both patients with pSS and controls, one for discovery and one for replication, were included in this study. CD4+ T cells and CD19+ B cells were isolated from peripheral blood mononuclear cells by magnetic microbeads and expression of miRNAs was profiled using the Exiqon Human miRNome panel I analysing 372 miRNAs...
September 15, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28916184/role-of-the-il-12-il-35-balance-in-sj%C3%A3-gren-s-syndrome
#12
Olivier Fogel, Elodie Rivière, Raphaèle Seror, Gaetane Nocturne, Saida Boudaoud, Bineta Ly, Jacques-Eric Gottenberg, Véronique Le Guern, Jean-Jacques Dubost, Joanne Nititham, Kimberly E Taylor, Philippe Chanson, Philippe Dieudé, Lindsey A Criswell, Bernd Jagla, Alice Thai, Michael Mingueneau, Xavier Mariette, Corinne Miceli-Richard
BACKGROUND: An interferon (IFN) signature is involved in the pathogenesis of primary Sjögren's syndrome (pSS), but whether the signature is type 1 or 2 remains controversial. Mouse models and genetic studies suggested the involvement of T helper 1 and type 2 IFN pathways. Likewise, polymorphisms of interleukin 12A gene (IL-12A), which encodes for IL-12p35, have been associated with pSS. IL-12p35 subunit is shared by 2 heterodimers, IL-12 and IL-35. OBJECTIVE: To confirm the genetic association of IL-12A polymorphism and pSS and elucidate the involvement of the IL-12/IL-35 balance in pSS by functional studies...
September 12, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28914543/modified-conducting-polymer-hole-injection-layer-for-high-efficiency-perovskite-light-emitting-devices-enhanced-hole-injection-and-reduced-luminescence-quenching
#13
Xue-Feng Peng, Xiao-Yan Wu, Xia-Xia Ji, Jie Ren, Qi Wang, Guo-Qing Li, Xiao-Hui Yang
Modification of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) with sodium-poly(styrenesulfonate) leads to a ca. 0.3 eV increase in the work function and 15 times enhancement in the photoluminescence intensity of the overlying perovskite layer, which is closely correlated with the formation of a highly PSS-enriched top layer. As a direct result, the hybrid halide perovskite light-emitting devices with a modified PEDOT:PSS layer show the maximum external quantum efficiency of 7.2% and power efficiency of 19...
September 15, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28914367/no-association-of-single-nucleotide-polymorphisms-within-h19-and-hox-transcript-antisense-rna-hotair-with-genetic-susceptibility-to-systemic-lupus-erythematosus-rheumatoid-arthritis-and-primary-sj%C3%A3-gren-s-syndrome-in-a-chinese-han-population
#14
An-Fang Huang, Lin-Chong Su, Hong Jia, Yi Liu, Wang-Dong Xu
The H19 (rs2839698, rs3741219) and HOTAIR (rs920778) polymorphisms were related to many kinds of cancers. However, these polymorphisms have been scarcely explored in different autoimmune diseases. Here, we aimed to examine the association of the polymorphisms with susceptibility to or protection against systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and primary Sjögren's syndrome (pSS) among Chinese Han patients. We conducted a case-control study including 800 patients (300 with SLE, 350 with RA, and 150 with pSS) and 350 healthy control individuals...
September 15, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28914228/an-integrated-case-management-model-to-assist-pacific-youth-offenders-and-their-families-in-australia
#15
Jioji Ravulo
Pasifika Support Services (PSS) was a program managed by a nongovernment organization, Mission Australia, and funded by the New South Wales Premiers Office to meet the needs of young offenders from a Pacific background. PSS ran from June 2005 to June 2009 and implemented a cost-effective integrated case management model with the New South Wales Police Force adapted to address social risk factors specific to Pacific youth offenders and family support networks. Sixty young people were reviewed regarding the outcomes achieved through their participation, further supported by an evaluation carried out by an external evaluator who found that 65% of participants did not reoffend after 18 months of completing the program...
December 1, 2016: Care Management Journals: Journal of Case Management ; the Journal of Long Term Home Health Care
https://www.readbyqxmd.com/read/28913747/primary-sj%C3%A3-gren-s-syndrome-extraglandular-manifestations-and-hydroxychloroquine-therapy
#16
J Demarchi, S Papasidero, M A Medina, D Klajn, R Chaparro Del Moral, O Rillo, V Martiré, G Crespo, A Secco, A Catalan Pellet, C Amitrano, C Crow, C Asnal, P Pucci, F Caeiro, N Benzanquen, J P Pirola, M Mayer, F Zazzetti, S Velez, J Barreira, N Tamborenea, L Santiago, L Raiti
The use of hydroxychloroquine (HCQ) in Primary Sjögren's Syndrome (pSS) has been assessed in different studies over the last years, with conflicting results regarding its efficacy in sicca syndrome and extraglandular manifestations (EGM). The goal of this study was to compare the incidence rate of EGM in pSS patients with and without HCQ therapy.We performed a multicenter retrospective study, including patients with pSS (European classification criteria) with at least 1 year of follow-up. Subjects with concomitant fibromyalgia, autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis were excluded...
September 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28910075/mechanochemical-synthesis-of-pedot-pss-hydrogels-for-aqueous-formulation-of-li-ion-battery-electrodes
#17
Georgiana Sandu, Bruno Ernould, Julien Rolland, Nathalie Cheminet, Jeremy Brassinne, Pratik Das, Yaroslav Filinchuk, Luhua Cheng, Lidiya Komsiyska, Philippe Dubois, Sorin Melinte, Jean-François Gohy, Roberto Lazzaroni, Alexandru Vlad
Water-soluble binders can enable greener and cost effective Li-ion battery manufacturing by eliminating the standard fluorine-based formulations and associated organic solvents. The issue with water-based dispersions, however, remains the difficulty to stabilize them, requiring additional processing complexity. Herein, we show that mechanochemical conversion of a regular poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) water-based dispersion produces a hydrogel that meets all the requirements as binder for lithium-ion battery electrode manufacture...
September 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28910071/a-simple-incl3-doped-pedot-pss-and-uv-ozone-treatment-strategy-external-quantum-efficiency-up-to-21-for-solution-processed-organic-light-emitting-devices-with-a-thermally-activated-delayed-fluorescence-emitter
#18
Tao Zhou, Guohua Xie, Shaolong Gong, Manli Huang, Jiajia Luo, Chuluo Yang
A low-cost and easy-processed scheme for solution processed organic light-emitting devices (OLEDs) was provided to overcome the flaws of poly(styrene sulfonic acid)-doped poly(3,4-ethylenedioxythiphene) (PEDOT:PSS) together with the indium tin oxide (ITO) anode. The modified PEDOT:PSS with higher work function (5.66 eV), higher conductivity and more efficient hole injecting ability was obtained by simply mixing the aqueous PEDOT:PSS with InCl3 and then consecutive ultraviolet-ozone treatment. The simply structured and solution-processed OLEDs with our modified PEDOT:PSS achieved very high external quantum efficiency of 21...
September 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28906515/study-of-the-presence-of-spherical-deformations-on-the-al-top-electrode-due-to-electroforming-in-rewritable-organic-resistive-memories
#19
J A Ávila-Niño, M Reyes-Reyes, R López-Sandoval
Physical deformations are observed at the top electrodes during the electroforming process in Al/PEDOT:PSS + nitrogen doped multiwalled carbon nanotube (N-MWCNTs)/Al rewritable resistive memory devices. These physical deformations arise from electrochemical reactions, i.e., a reduction reaction in the native Al oxide layer, which are similar to those reported in TiO2-based resistive memory devices. These memory devices are electroformed at the ON state using an ∼-2 V pulse or at the OFF state using an ∼3 V pulse...
September 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28905360/distress-levels-in-pregnant-and-matched-non-pregnant-women
#20
Carol Cornsweet Barber, Jessica Steadman
This study examined self-rated symptoms of distress (Depression Anxiety and Stress Scale-DASS-21 and Perceived Stress Scale-PSS-4) among 93 pregnant women and a comparison group of 93 non-pregnant women matched on age and educational attainment. There were no significant differences between the groups, either on mean levels of distress or on proportions above a clinical cut-off point. Overall, 22%, 31% and 16% of pregnant women reported experiencing at least moderate levels of depression, anxiety and stress, respectively...
September 14, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
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