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https://www.readbyqxmd.com/read/28729155/incidence-mortality-and-causes-of-death-in-physician-diagnosed-primary-sj%C3%A3-gren-s-syndrome-in-korea-a-nationwide-population-based-study
#1
Hyun Jung Kim, Kyoung Hoon Kim, Hoo Jae Hann, Seungjin Han, Yuri Kim, Sang Hyuk Lee, Dong Sook Kim, Hyeong Sik Ahn
OBJECTIVES: The objective of this study was to investigate the epidemiological features of primary Sjögren's syndrome (pSS) in Korea at a national level, including the incidence, mortality, and causes of death. METHODS: We used a national, population-based registry database called the Rare Intractable Disease Registration Program from the Health Insurance Review and Assessment Service to obtain pSS patient data for the period between 2010 and 2014. pSS was diagnosed by a physician based on uniform criteria...
March 8, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28726870/highly-efficient-photosensitizers-with-aggregation-induced-emission-characteristics-obtained-through-precise-molecular-design
#2
Shidang Xu, Wenbo Wu, Xiaolei Cai, Chong-Jing Zhang, Youyong Yuan, Jing Liang, Guangxue Feng, Purnima Manghnani, Bin Liu
We herein report a new strategy to obtain highly efficient photosensitizers (PSs) by reducing the singlet-triplet energy gap (ΔEST) and blocking the non-radiative decay pathways. Through precise molecular design, TP1-8 were synthesized to exhibit predictable properties including moderate to high photosensitizing efficacy, tunable absorption and emission wavelengths and aggregation-induced emission characteristics.
July 20, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28723074/paper-based-bimodal-sensor-for-electronic-skin-applications
#3
Minhyun Jung, Kyungkwan Kim, Bumjin Kim, Haena Cheong, Kwanwoo Shin, Oh-Sun Kwon, Jong-Jin Park, Sanghun Jeon
We present the development of a flexible bimodal sensor using a paper platform and ink-jet printing method, which are suited for low-cost fabrication processes and realization of flexible devices. In this study, we employed a vertically stacked bimodal device architecture in which a temperature sensor is stacked on top of a pressure sensor and operated on different principles, allowing the minimization of interference effects. For the temperature sensor placed in the top layer, we used the thermoelectric effect and formed a closed-loop thermocouple composed of two different printable inks: conductive PEDOT:PSS and silver nanoparticles on a flexible paper platform, and obtained temperature-sensing capability over a wide range (150 ℃)...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28722669/hydroxychloroquine-and-risk-of-cancer-in-patients-with-primary-sj%C3%A3-gren-syndrome-propensity-score-matched-landmark-analysis
#4
Yao-Fan Fang, Yen-Fu Chen, Ting-Ting Chung, Lai-Chu See, Kuang-Hui Yu, Shue-Fen Luo, Chang-Fu Kuo, Jenn-Haung Lai
Hydroxychloroquine inhibits systemic inflammation and autophagy and may thus have antineoplastic effects [1]. We investigated the effect of hydroxychloroquine on cancer risk in patients with primary Sjögren syndrome(pSS). We used the Taiwan National Health Insurance Database to compare cancer incidence between incident pSS patients with or without at least 6-month hydroxychloroquine use within a 1- or 3-year period. Propensity score matched landmark analysis was used. We included 4194 alive patients without cancer 1 year after pSS diagnosis from 2000 through 2005...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28722580/rapid-active-sampling-surveys-as-a-tool-to-evaluate-factors-associated-with-acute-gastroenteritis-and-norovirus-infection-among-children-in-rural-guatemala
#5
Daniel Olson, Molly M Lamb, Maria R Lopez, Maria A Paniagua-Avila, Alma Zacarias, Gabriela Samayoa-Reyes, Celia Cordon-Rosales, Edwin J Asturias
We examined burden and factors associated with norovirus (NoV) acute gastroenteritis (AGE) among children in rural Guatemala. Children age 6 weeks to 17 years were enrolled into three AGE surveillance groups, using two-stage cluster sampling: a prospective participatory syndromic surveillance (PSS) cohort and two cross-sectional rapid active sampling (RAS) surveys, conducted from April 2015 to February 2016. Epidemiologic and NoV testing data were used to identify factors associated with NoV infection, AGE, and NoV+ AGE...
June 19, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719364/is-there-a-link-between-self-perceived-stress-and-physical-activity-levels-in-scottish-adolescents
#6
Joe Cowley, John Kiely, Dave Collins
Purpose Accumulating life stress is a driving factor underlying the most pervasive, incapacitating health conditions in 21st century, First World societies. The most widely supported strategy, for remediating the negative health consequences of elevated life stress, is physical activity (PA). Evidence also suggests accumulating life stress impedes PA uptake. Thus, ironically, persistently elevated life stress not only negatively impacts multiple dimensions of health, simultaneously it may also reduce likelihood of participation in the most effective remediating strategy, PA...
July 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28718618/graphene-oxide-by-uv-ozone-treatment-as-efficient-hole-extraction-layer-for-highly-efficient-and-stable-polymer-solar-cells
#7
Yingdong Xia, Yufeng Pan, Haijuan Zhang, Jian Qiu, Yiting Zheng, YongHua Chen, Wei Huang
Hole extraction layer has significant impact on achieving high-efficiency polymer solar cells (PSCs). Here, we report an efficient approach to by direct UV-Ozone treatment larger device performance enhancement employing grapheme oxide (GO). The dramatically performance enhancement of PSCs with P3HT:PCBM blend as an active layer was demonstrated by UV-Ozone treated GO for 30 min: best PCE of 4.18%, FF of 0.63, Jsc of 10.94 mA cm-2, and Voc of 0.61 V, which is significantly higher than the untreated GO (1.82%) and highly comparable PEDOT:PSS-based PSCs (3...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28716739/phototoxicity-in-a-laryngeal-cancer-cell-line-enhanced-by-a-targeting-amphiphilic-chlorin-photosensitizer
#8
Milene N O Moritz, Carlos Rossa, Kleber T de Oliveira, Marciana P Uliana, Janice R Perussi
BACKGROUND: Photodynamic therapy (PDT) has been established in several countries as an alternative therapy for the treatment of various malignancies. This therapy involves the incorporation of a photosensitizer (PS) that is activated by visible light and form reactive oxygen species leading to target cell death by apoptosis or necrosis. Previously, our group has demonstrated that CHL-T (semi-synthesized from chlorophyll a and containing a linked solubilizing group TRISMA(®)) presented a pronounced potential to induce death in HeLa cell line after PDT...
July 14, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28712475/effectiveness-of-acupuncture-therapy-on-stress-in-a-large-urban-college-population
#9
Stefanie Schroeder, James Burnis, Antony Denton, Aaron Krasnow, T S Raghu, Kimberly Mathis
This study is a randomized controlled clinical trial to study the effectiveness of acupuncture on the perception of stress in patients who study or work on a large, urban college campus. The hypothesis was that verum acupuncture would demonstrate a significant positive impact on perceived stress as compared to sham acupuncture. This study included 111 participants with high self-reported stress levels who either studied or worked at a large, urban public university in the southwestern United States. However, only 62 participants completed the study...
June 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28712350/defining-peer-roles-and-status-among-community-health-workers-and-peer-support-specialists-in-integrated-systems-of-care
#10
Allen S Daniels, Sue Bergeson, Keris Jän Myrick
Current strategies for integrating general medical and behavioral health services focus primarily on improving the coordination of care and expanding team-based services. Absent from most discussion has been a focus on the workforces that provide the bulk of community-based outreach, engagement, activation, motivational support, and self-management: community health workers (CHWs) and peer support specialists (PSSs). CHWs have primarily been deployed in general medical care and PSSs in behavioral health care...
July 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28710097/germinal-centres-in-diagnostic-labial-gland-biopsies-of-patients-with-primary-sj%C3%A3-gren-s-syndrome-are-not-predictive-for-parotid-malt-lymphoma-development
#11
Erlin A Haacke, Bert van der Vegt, Arjan Vissink, Fred K L Spijkervet, Hendrika Bootsma, Frans G M Kroese
OBJECTIVE: Patients with primary Sjögren's syndrome (pSS) have an increased risk of developing non-Hodgkin's lymphoma (NHL), particularly parotid gland mucosa-associated lymphoid tissue (MALT) lymphomas. Presence of germinal centres (GCs) in labial gland biopsies has been suggested as predictive factor for NHL. We assessed whether presence of GCs is increased in labial gland biopsies from patients with pSS who developed parotid MALT lymphoma, the dominant NHL-subtype in pSS, compared with patients with pSS who did not develop lymphoma...
July 14, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28707513/cross-cultural-adaptation-and-validation-of-the-danish-10-item-connor-davidson-resilience-scale-among-hospital-staff
#12
Line Skjødt Lauridsen, Morten Vejs Willert, Anita Eskildsen, David Høyrup Christiansen
OBJECTIVES: The 10-item Connor-Davidson Resilience Scale (CD-RISC 10) is a brief instrument measuring resilience in adults. The scale has shown sound psychometric properties in different populations and cultures. Our objectives were to cross-culturally adapt the CD-RISC 10 into Danish and to establish the psychometric properties of the Danish version in terms of internal consistency, construct validity and longitudinal validity. METHODS: The CD-RISC 10 was translated using established guidelines...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28707007/wrinkle-and-crack-dependent-charge-transport-in-a-uniaxially-strained-conducting-polymer-film-on-a-flexible-substrate
#13
Biporjoy Sarkar, Dillip K Satapathy, Manu Jaiswal
We investigate charge transport in poly(3,4-ethylene dioxythiophene) polystyrene sulfonate (PEDOT:PSS) films on functionalized polydimethylsiloxane (PDMS) substrates under varying uniaxial strain up to 16%. Strong anisotropy in transport is observed at a large applied strain (ε > 4%), which is understood in terms of an extrinsic process, involving a change in density of cracks from a few cracks per mm at ε = 4% to >100 cracks per mm at ε = 16%. The quasi-periodic cracks are aligned perpendicular to the stretching direction...
July 14, 2017: Soft Matter
https://www.readbyqxmd.com/read/28704999/multilayer-poly-3-4-ethylenedioxythiophene-dexamethasone-and-poly-3-4-ethylenedioxythiophene-polystyrene-sulfonate-carbon-nanotubes-coatings-on-glassy-carbon-microelectrode-arrays-for-controlled-drug-release
#14
Elisa Castagnola, Stefano Carli, Maria Vomero, Alice Scarpellini, Mirko Prato, Noah Goshi, Luciano Fadiga, Sam Kassegne, Davide Ricci
The authors present an electrochemically controlled, drug releasing neural interface composed of a glassy carbon (GC) microelectrode array combined with a multilayer poly(3,4-ethylenedioxythiophene) (PEDOT) coating. The system integrates the high stability of the GC electrode substrate, ideal for electrical stimulation and electrochemical detection of neurotransmitters, with the on-demand drug-releasing capabilities of PEDOT-dexamethasone compound, through a mechanically stable interlayer of PEDOT-polystyrene sulfonate (PSS)-carbon nanotubes (CNT)...
July 13, 2017: Biointerphases
https://www.readbyqxmd.com/read/28701678/paget-schroetter-syndrome-in-a-baseball-pitcher
#15
Shusuke Yagi, Minoru Mitsugi, Teruaki Sangawa, Masashi Akaike, Masataka Sata
Paget-Schroetter syndrome (PSS) is thrombosis of the deep veins draining the upper extremity due to anatomic abnormalities of the thoracic outlet that cause subclavian compression and subsequent thrombosis, leading to thrombus formation in the subclavian vein. Vigorous arm activity in sports is a known risk factor. Here, we report a case of Paget-Schroetter syndrome in a 31-year-old male non-professional baseball pitcher.
July 13, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28697597/core-assisted-formation-of-porphyrin-j-aggregates-in-ph-sensitive-polyelectrolyte-microcapsules-followed-by-fluorescence-lifetime-imaging-microscopy
#16
Vanda Vaz Serra, Nuno G B Neto, Suzana M Andrade, Silvia M B Costa
A strategy assisted by an inorganic template was developed to promote the organized self-assembly of meso-(tetrakis)-(p-sulfonatophenyl)porphyrin (TSPP) on pH sensitive core-shell polyelectrolyte microcapsules (PECs) of poly(styrene sulfonate) (PSS) and poly(allylamine hydrochloride) (PAH). A key feature of this strategy is the use of template CaCO3 microparticles as a nucleation site endorsing inside-outside directional growth of porphyrin aggregates. Using this approach, TSPP self-assembly in positively charged PECs with CaCO3 (PAH/PSS)2PAH as a sequence of layers was successfully achieved using pH mild conditions (pH 3)...
July 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28695726/water-soluble-2d-transition-metal-dichalcogenides-as-the-hole-transport-layer-for-highly-efficient-and-stable-p-i-n-perovskite-solar-cells
#17
Peng Huang, Zhaowei Wang, Yanfeng Liu, Kaicheng Zhang, Ligang Yuan, Yi Zhou, Bo Song, Yongfang Li
As a hole-transport layer (HTL) material, poly(3,4-ethylenedioxythiophene):polystyrene-sulfonate (PEDOT:PSS) was often criticized for its intrinsic acidity and hygroscopic effect that would in the long run affect the stability of perovskite solar cells (Pero-SCs). As alternatives, herein water-soluble two-dimensional (2D) transition metal dichalcogenides (TMDs), such as MoS2 and WS2 were used as HTLs in p-i-n Pero-SCs. It was found that the content of 1T phase in 2D TMDs HTLs is centrally important to the power conversion efficiencies (PCEs) of Pero-SCs, and the 1T-rich TMDs (as achieved from exfoliation and without postheating) lead to much higher PCEs...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28695197/ferroelectric-polarization-induces-electronic-nonlinearity-in-ion-doped-conducting-polymers
#18
Simone Fabiano, Negar Sani, Jun Kawahara, Loïg Kergoat, Josefin Nissa, Isak Engquist, Xavier Crispin, Magnus Berggren
Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is an organic mixed ion-electron conducting polymer. The PEDOT phase transports holes and is redox-active, whereas the PSS phase transports ions. When PEDOT is redox-switched between its semiconducting and conducting state, the electronic and optical properties of its bulk are controlled. Therefore, it is appealing to use this transition in electrochemical devices and to integrate those into large-scale circuits, such as display or memory matrices...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28694836/metastatic-prostatic-stromal-sarcoma-a-challenging-diagnosis-on-fine-needle-aspiration-with-broad-differential-diagnosis
#19
Muhammad Siddique Khurram, Ghassan Tranesh, Ramen Sakhi, Ameer Hamza, Warda Ibrar, Roohi Bano
Prostatic stromal sarcomas (PSS) are rare solid organ mesenchymal sarcomas. PSS may pose difficult diagnostic challenges on fine needle aspiration biopsy. We report a 48-year-old man diagnosed with metastatic high grade prostatic stromal sarcoma by a CT-scan guided fine needle aspiration (FNA) biopsy of a right lower lung lobe nodule. We reviewed the literature on the epidemiologic, cyto-histological, and immunophenotypic findings and discussed the differential diagnosis for this rare entity.
2017: CytoJournal
https://www.readbyqxmd.com/read/28692354/potential-protective-effects-of-polysaccharide-extracted-from-ulva-lactuca-against-male-reprotoxicity-induced-by-thiacloprid
#20
Intissar Kammoun, Intidhar Bkhairia, Fatma Ben Abdallah, Imen Jaballi, Naourez Ktari, Ons Boudawara, Moncef Nasri, Neji Gharsallah, Ahmed Hakim, Ibtissem Ben Amara
CONTEXT: Polysaccharides (PSs) from seaweeds have been reported to possess biological activity of potential medicinal values. OBJECTIVE: The current study was conducted to establish the protective effects of PS extracted from Ulva lactuca against oxidative stress induced by Thiacloprid (THC) in the rat reproductive system. MATERIALS AND METHODS: Rats were exposed either to THC, THC + PS (100 mg/kg), or THC + PS (200 mg/kg). RESULTS: Our study showed that THC induced severe disorders in the functional sperm parameters...
July 10, 2017: Archives of Physiology and Biochemistry
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