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https://www.readbyqxmd.com/read/28921656/animal-models-for-studying-the-etiology-and-treatment-of-low-back-pain
#1
REVIEW
Changgui Shi, Sujun Qiu, Scott M Riester, Vaskar Das, Bingqian Zhu, Atiyayein A Wallace, Andre J van Wijnen, Fackson Mwale, James C Iatridis, Daisuke Sakai, Gina Votta-Velis, Wen Yuan, Hee-Jeong Im
Chronic low back pain is a major cause of disability and health care costs. Effective treatments are inadequate for many patients. Animal models are essential to further understanding of the pain mechanism and testing potential therapies. Currently, a number of preclinical models have been developed attempting to mimic aspects of clinical conditions that contribute to low back pain. This review focused on describing these animal models and the main behavioral tests for assessing pain in each model. Animal models of low back pain can be divided into the following five categories: discogenic low back pain, radicular back pain, facet joint osteoarthritis back pain, muscle-induced low back pain, and spontaneous occurring low back pain models...
September 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28919229/early-outcomes-of-endoscopic-contralateral-foraminal-and-lateral-recess-decompression-via-an-interlaminar-approach-in-patients-with-unilateral-radiculopathy-from-unilateral-foraminal-stenosis
#2
Hyeung Sung Kim, Ravish Patel, Byapak Paudel, Jee-Soo Jang, Il-Tae Jang, Seong-Hoon Oh, Jae Eun Park, Sol Lee
OBJECTIVE: Percutaneous endoscopic contralateral interlaminar lumbar foraminotomy (PECILF) for lumbar degenerative spinal stenosis is an established procedure. Better preservation of contralateral facet joint compared to that of the approach side has been demonstrated with uniportal bilateral decompression. The aim of this retrospective case series was to analyze the early clinical and radiological outcomes of standalone contralateral foraminotomy and lateral recess decompression using PECILF...
September 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28903535/modeling-the-multiple-facets-of-speciation-with-gene-flow-toward-inferring-the-divergence-history-of-lake-whitefish-species-pairs-coregonus-clupeaformis
#3
Clément Rougeux, Louis Bernatchez, Pierre-Alexandre Gagnaire
Parallel divergence across replicated species pairs occurring in similar environmental contrasts may arise through distinct evolutionary scenarios. Deciphering whether such parallelism actually reflects repeated parallel divergence driven by divergent selection or a single divergence event with subsequent gene flow needs to be ascertained. Reconstructing historical gene flow is therefore of fundamental interest to understand how demography and selection jointly shaped genomic divergence during speciation. Here, we use an extended modeling framework to explore the multiple facets of speciation-with-gene-flow with demo-genetic divergence models that capture both temporal and genomic variation in effective population size and migration rate...
August 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28899699/factors-associated-with-lumbar-disc-hernia-recurrence-after-microdiscectomy
#4
G Camino Willhuber, G Kido, M Mereles, J Bassani, M Petracchi, C Elizondo, M Gruenberg, C Sola
INTRODUCTION: Lumbar disc hernias are a common cause of spinal surgery. Hernia recurrence is a prevalent complication. OBJECTIVE: To analyse the risk factors associated with hernia recurrence in patients undergoing surgery in our institution. MATERIALS AND METHODS: Lumbar microdiscectomies between 2010 and 2014 were analysed, patients with previous surgeries, extraforaminales and foraminal hernias were excluded. Patients with recurrent hernia were the case group and those who showed no recurrence were the control group...
September 9, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28898815/biomechanical-evaluation-of-different-surgical-procedures-in-single-level-transforaminal-lumbar-interbody-fusion-in-vitro
#5
Yuanwu Cao, Fubing Liu, Shengcheng Wan, Yun Liang, Chun Jiang, Zhenzhou Feng, Xiaoxing Jiang, Zixian Chen
BACKGROUNDS: A variety of improved surgical methods were adopted in the transforaminal lumbar interbody fusion. A mechanical stability provides an ideal environment for the formation of a fusion mass and is the basis of their good outcomes. The object of this study is to evaluate the initial similarities and differences of four commonly-used posterior surgical procedures biomechanically. METHODS: Biomechanical testing was performed at L3-4 motion segment in 6 fresh-frozen human cadaveric lumbar spines (L2-L5), including the following sequentially tested configurations: 1) intact motion segment; 2) bilateral pedicle screw fixation; 3) unilateral pedicle screw fixation; 4) unilateral pedicle screw plus contralateral translaminar facet joint screw fixation according to the Magerl technique; and 5) bilateral pedicle screw fixation with bilateral facetectomies...
September 5, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28888523/mechanical-alignment-technique-for-tka-are-there-intrinsic-technical-limitations
#6
Charles Rivière, FarhadIranpour, Edouard Auvinet, ArashAframian, Kirsty Asare, Simon Harris, Justin Cobb, Sébastien Parratte
BACKGROUND: Mechanically aligned (MA) total knee arthroplasty (TKA) is affected by disappointing functional outcomes in spite of the recent improvements in surgical precision and implant designs. This might suggest the existence of intrinsic technical limitations. Our study aims to compare the prosthetic and native trochlear articular surfaces and to estimate the extent of collateral ligament imbalance which is technically un-correctable by collateral ligament release when TKA implants are mechanically aligned...
September 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28888405/anatomic-locking-plate-for-displaced-intraarticular-calcaneal-fracture-design-and-application
#7
Chia-Hung Chu, Yan-Yu Chen, Kang-Ping Lin, Wen-Chuan Chen, Pei-Yuan Lee
Calcaneal fracture can lead to long-term disability and have a considerable economic effect. Most calcaneal fractures are intraarticular fractures involving the posterior facet of the subtalar joint. Treating displaced intraarticular calcaneal fractures is complicated because of the lack of an optimal treatment option. Internal fixation typically involves screw-and-plate implants, which can be unfavorable owing to the lack of an anatomic design and the intraoperative bending required for the plate to contour to the irregular surface of the calcaneus...
September 6, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28887021/improving-value-in-total-joint-arthroplasty-a-comprehensive-patient-education-and-management-program-decreases-discharge-to-post-acute-care-facilities-and-post-operative-complications
#8
Christopher E Pelt, Jeremy M Gililland, Jill A Erickson, Dory E Trimble, Mike B Anderson, Christopher L Peters
BACKGROUND: A step-by-step approach to creating a comprehensive patient education, expectation, and management program is described with the aim of reducing discharges to post-acute care centers (PACs) following total joint arthroplasty (TJA). We hypothesized that by lowering discharges to PACs, readmissions and reoperations would also decrease. METHODS: Following the implementation of a multi-faceted patient education and management program, we retrospectively reviewed 927 TJAs who underwent surgery 12 months before (n = 465) and after (n = 462) the program was implemented...
August 19, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28885649/l5-radiculopathy-secondary-to-migration-of-a-revision-stemmed-acetabular-cup
#9
Jesús Moreta, Oscar L Casado-Verdugo, Fernando Labayru
INTRODUCTION: Stemmed acetabular components are used in patients undergoing revision total hip arthroplasty in cases with major acetabular defects or pelvic discontinuity. Conflicting results relating to the survival of the component, and complication rates are reported in the literature. We present a case of L5 radiculopathy secondary to proximal migration of this device. CASE DESCRIPTION: A 79-year-old man was admitted to our department in 2012 with increasing pain and paresthesias, initially diagnosed as left L5 radiculopathy...
September 2, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28884103/lateral-patellar-retinacular-release-changes-over-the-last-ten-years
#10
REVIEW
Leonardo Pini Rosalem Marciano da Fonseca, Ednei Haruo Kawatake, Alberto de Castro Pochini
Lateral retinacular release is a useful resource in knee surgery that can be used for disorders of the extensor mechanism. For many years, it was indiscriminately used in the treatment of the various patellofemoral joint alterations, with conflicting functional results. This study aimed to analyze the changes that have occurred in the indications and clinical effectiveness of lateral retinacular release by reviewing the relevant literature of the past ten years, comparing it to the classic literature on the subject...
June 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28882525/multi-level-posterior-foraminotomy-with-laminoplasty-versus-laminoplasty-alone-for-cervical-spondylotic-myelopathy-with-radiculopathy-a-comparative-study
#11
Dong-Ho Lee, Jae Hwan Cho, Chang Ju Hwang, Choon Sung Lee, Chunghwan Kim, Jung-Ki Ha
BACKGROUND CONTEXT: Conventional laminoplasty is useful for expanding a stenotic spinal canal. However, it has limited use for the decompression of accompanying neural foraminal stenosis. As such, an additional posterior foraminotomy could be simultaneously applied, although this procedure carries a risk of segmental kyphosis and instability. PURPOSE: The aim was to elucidate the long-term surgical outcomes of additional posterior foraminotomy with a laminoplasty for cervical spondylotic myelopathy (CSM) with radiculopathy...
September 4, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28879900/simultaneous-odontoid-excision-with-bilateral-posterior-c1-2-distraction-and-stabilization-utilizing-bilateral-posterolateral-corridors-and-a-single-posterior-midline-incision
#12
Arun K Srivastava, Sanjay Behari, Jayesh Sardhara, Kuntal Kanti Das
A simultaneous odontoid decompression and bilateral posterior atlanto-axial facetal distraction, C1-2 joint spacer/bone graft placement and stabilization may be performed utilizing the 'posterior-only' approach. This procedure may be performed utilizing a single posterior midline incision, a bilateral posterior approach to the C1-2 facet joints and a bilateral posterolateral approach to the odontoid process and C2 body. It may be carried out in situations where a C1-2 non-reduction/partial reduction using a 'posterior alone' procedure is anticipated due to the complex bony/soft tissue configuration anterior at the thecal sac existing at the cervicomedullary junction...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28879370/radiofrequency-facet-joint-denervation-in-the-lumbar-spine
#13
Doina Thomas, Klaus J Schnake
No abstract text is available yet for this article.
September 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28875092/thoracolumbar-cortical-screw-placement-with-interbody-fusion-technique-and-considerations
#14
Michael Karsy, Michael R Jensen, Kyril Cole, Jian Guan, Andrea Brock, Chad Cole
A surge in interest in cortical bone trajectory (CBT), first described by Santoni in 2009, may be a result of its numerous advantages, including reduced surgical incision length and lateral dissection, limited disruption of the facet joints, and decreased blood loss. In addition, CBT offers improved screw pullout strength and the ability to perform hybrid constructs with pedicle screws using minimally invasive approaches. However, one of the main limitations of the technique involves the small screw size, which limits the potential for long-segment constructs...
July 2, 2017: Curēus
https://www.readbyqxmd.com/read/28860213/-18-f-sodium-fluoride-pet-mr-based-localization-and-quantification-of-bone-turnover-as-a-biomarker-for-facet-joint-induced-disability
#15
N W Jenkins, J F Talbott, V Shah, P Pandit, Y Seo, W P Dillon, S Majumdar
Our aim was to prospectively evaluate the relationship between low back pain-related disability and quantitative measures from [(18)F]-sodium fluoride ([(18)F]-NaF) MR imaging. Six patients with facetogenic low back pain underwent dynamic [(18)F]-NaF PET/MR imaging. PET metrics were correlated with clinical measures and MR imaging grading of lumbar facet arthropathy. A significant positive correlation was observed between maximum facet joint uptake rate and clinical disability (P < .05). These data suggest that dynamic [(18)F]-NaF PET may serve as a useful biomarker for facetogenic disability...
August 31, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28843706/variation-of-facet-joint-orientation-and-tropism-in-lumbar-degenerative-spondylolisthesis-and-disc-herniation-at-l4-l5-a-systematic-review-and-meta-analysis
#16
REVIEW
Ziyang Liu, Yuchen Duan, Xin Rong, Beiyu Wang, Hua Chen, Hao Liu
Although degenerative spondylolisthesis (DS) and lumber disc herniation (LDH) are common causes of back pain, the associations between the lumbar facet joint angle orientation and tropism in these conditions are still contentious. The objective of the meta-analysis was to identify the role of facet joint orientation and tropism on the development of lumbar degenerative disease, including DS and LDH. Electronic searches of PubMed and Embase were conducted up to April 2017. P value<0.05 was regarded as significant...
October 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28832200/use-of-particulated-juvenile-articular-cartilage-allograft-for-osteochondral-lesions-of-the-wrist
#17
Daniel E Hess, Brian C Werner, D Nicole Deal
BACKGROUND: Articular cartilage injuries are a common injury among young, active patients, and the most appropriate treatment for these injuries remains controversial. A promising new technology in the treatment of high-grade cartilage injuries is particulated juvenile articular cartilage (PJAC) allograft (DeNovo NT, Zimmer, Warsaw, Indiana). This has been shown to be successful in multiple joints including the knee, talus, and elbow. No studies or case reports exist in supporting or discouraging its use in injuries of the wrist, in specific, the scaphoid...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28831392/pathoanatomic-risk-factors-for-instability-and-adjacent-segment-disease-in-lumbar-spine-how-to-use-topping-off
#18
REVIEW
J Bredow, L Löhrer, J Oppermann, M J Scheyerer, R Sobottke, P Eysel, J Siewe
PURPOSE: The goal of this review is to identify criteria indicating implantation of hybrid system into lumbar spine and to evaluate general benefits of use. METHODS: A systematic review of literature was performed using current randomized clinical trials, reviews, and meta-analyses. Data sources included relevant literature of human studies identified through searches of Medline Library until May 2015. RESULTS: Predisposing factors for Adjacent Segment Disease (ASDi) are discussed in literature: laminar horizontalization, insufficiency of fascia thoracolumbalis, facet tropism, and facet sagittalization...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28826710/biomechanical-analysis-of-bilateral-facet-joint-stabilization-using-bio-derived-tendon-for-posterior-cervical-spine-motion-reservation-in-goats
#19
Bei-Yu Wang, Ting-Kui Wu, Hao Liu, Wei-Guang Hou, Li-Tai Ma, Yu-Xiao Deng, Chen Ding, Ying Hong, Hui-Qi Xie
OBJECTIVES: To investigate the biomechanical properties of a novel stabilization method for posterior cervical motion preservation using bio-derived freeze-dried tendon. METHODS: Experiments were conducted both in vitro and in vivo. For the in vitro group, fifteen fresh-frozen goat spines (C1-C7) were randomly divided into three subgroups: intact (INT-vitro, n=5), injury model (IM-vitro, n=5) and bilateral facet joint stabilization (BFJS-vitro, n=5) subgroups. For the in vivo group, fifteen adult goats were randomly divided into three experimental subgroups: INT-vivo subgroup (n=5); IM-vivo subgroup (n=5); BFJS-vivo subgroup (n=5)...
August 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28822473/influence-of-spinal-manipulative-therapy-force-magnitude-and-application-site-on-spinal-tissue-loading-a-biomechanical-robotic-serial-dissection-study-in-porcine-motion-segments
#20
Martha Funabashi, François Nougarou, Martin Descarreaux, Narasimha Prasad, Greg Kawchuk
OBJECTIVE: In order to define the relation between spinal manipulative therapy (SMT) input parameters and the distribution of load within spinal tissues, the aim of this study was to determine the influence of force magnitude and application site when SMT is applied to cadaveric spines. METHODS: In 10 porcine cadavers, a servo-controlled linear actuator motor provided a standardized SMT simulation using 3 different force magnitudes (100N, 300N, and 500N) to 2 different cutaneous locations: L3/L4 facet joint (FJ), and L4 transverse processes (TVP)...
July 2017: Journal of Manipulative and Physiological Therapeutics
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