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https://www.readbyqxmd.com/read/29043143/focal-segmental-glomerulosclerosis-associated-with-mitochondrial-disease
#1
Kenneth Lim, David Steele, Andrew Fenves, Ravi Thadhani, Eliot Heher, Amel Karaa
Primary mitochondrial diseases (MD) are complex, heterogeneous inherited diseases caused by mutations in either the mitochondrial or nuclear DNA. Glomerular diseases in MD have been reported with tRNA mutation m.3243A>G causing a syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). We describe here a case of focal segmental glomerulosclerosis (FSGS) associated with a new tRNA mutation site. A 34-year-old man with a history of living related kidney transplantation, diabetes, hearing loss, and developmental delay presented to the outpatient clinic with complaints of new behavioral difficulties, worsening symptoms, and brain involvement on imaging...
2017: Clin Nephrol Case Stud
https://www.readbyqxmd.com/read/29041823/therapists-cues-influence-lower-limb-muscle-activation-and-kinematics-during-gait-training-in-subacute-stroke
#2
Michelle Ploughman, Jennifer Shears, Susan Quinton, Cordell Flight, Michelle O'Brien, Phillip MacCallum, Megan C Kirkland, Jeannette M Byrne
PURPOSE: Symmetrical gait is a key goal of rehabilitation post-stroke. Therapists employ techniques such as verbal instruction and haptic cues to increase activation of paretic muscles. We examined whether verbal or tactile cueing altered spatiotemporal gait parameters, kinematics and electromyography (EMG) of lower limb muscles on the more-affected side within a training session. MATERIALS AND METHODS: Patients (n = 10) were recruited from rehabilitation services (<9 months post-stroke)...
October 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29040224/fes-assisted-cycling-improves-aerobic-capacity-and-locomotor-function-post-cva
#3
Stacey E Aaron, Catherine J VanDerwerker, Aaron E Embry, Jennifer H Newton, Samuel C K Lee, Chris M Gregory
PURPOSE: After a cerebrovascular accident (CVA) aerobic deconditioning contributes to diminished physical function. Functional Electrical Stimulation (FES)-assisted cycling is a promising exercise paradigm designed to target both aerobic capacity and locomotor function. This pilot study aimed to evaluate the effects of an FES-assisted cycling intervention on aerobic capacity and locomotor function in individuals post-CVA. METHODS: Eleven individuals with chronic (> 6 months) post-CVA hemiparesis completed an 8-week (3x/wk; 24 sessions) progressive FES-assisted cycling intervention...
October 16, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29037625/effects-of-proprioceptive-neuromuscular-facilitation-on-balance-strength-and-mobility-of-an-older-adult-with-chronic-stroke-a-case-report
#4
Christopher S Cayco, Edward James R Gorgon, Rolando T Lazaro
This study described the effects of a proprioceptive neuromuscular facilitation (PNF) program on balance, strength, and mobility in an older adult with chronic stroke. The patient was male, aged 69 years, with right hemiplegia for 17 years, and had diminished balance, balance confidence, lower extremity (LE) strength, and gait velocity. He received 1 h of PNF-based therapy thrice a week for six weeks. Outcome measures were: Mini-BESTest, limits of stability (LOS), Activities-Specific Balance Confidence Scale (ABC), Five Time Sit-to-Stand Test (FTSST), Upright Motor Control Test (UMCT), and 10 Meter Walk Test (10 MWT)...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29031023/whole-body-vibration-combined-with-treadmill-training-improves-walking-performance-in-post-stroke-patients-a-randomized-controlled-trial
#5
Wonjae Choi, Donghun Han, Junesun Kim, Seungwon Lee
BACKGROUND Stroke is characterized by an asymmetrical gait pattern that causes poor stability and reduces overall activity levels. The aim of this study was to investigate the effect of whole-body vibration combined with treadmill training (WBV-TT) on walking performance in patients with chronic stroke. MATERIAL AND METHODS Thirty ambulatory chronic stroke patients were randomly allocated to the WBV-TT group or the treadmill training (TT) group. The participants in the WBV-TT group performed 6 types of exercises on a vibrating platform for 4...
October 14, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29029646/paretic-versus-non-paretic-stepping-responses-following-pelvis-perturbations-in-walking-chronic-stage-stroke-survivors
#6
Juliet A M Haarman, Mark Vlutters, Richelle A C M Olde Keizer, Edwin H F van Asseldonk, Jaap H Buurke, Jasper Reenalda, Johan S Rietman, Herman van der Kooij
BACKGROUND: The effects of a stroke, such as hemiparesis, can severely hamper the ability to walk and to maintain balance during gait. Providing support to stroke survivors through a robotic exoskeleton, either to provide training or daily-life support, requires an understanding of the balance impairments that result from a stroke. Here, we investigate the differences between the paretic and non-paretic leg in making recovery steps to restore balance following a disturbance during walking...
October 13, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28994143/correlates-of-physical-activity-among-depressed-older-people-in-six-low-income-and-middle-income-countries-a-community-based-cross-sectional-study
#7
Davy Vancampfort, Brendon Stubbs, Nicola Veronese, James Mugisha, Nathalie Swinnen, Ai Koyanagi
OBJECTIVE: Despite the benefits of physical activity (PA) in older people with depression, many do not comply with the International PA guidelines. Thus, we investigated what factors influence PA participation among 915 community-dwelling older adults (aged ≥65 years) with depression in 6 low-income and middle-income countries (LMICs). METHODS: Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. The sample was restricted to those with DSM-IV depression or receiving depression treatment in the last 12 months...
October 10, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28988025/towards-an-objective-assessment-of-motor-function-in-sub-acute-stroke-patients-relationship-between-clinical-rating-scales-and-instrumental-gait-stability-indexes
#8
P Tamburini, D Mazzoli, R Stagni
The assessment of walking function alterations is a key issue to design effective rehabilitative interventions in sub-acute stroke patients. Nevertheless, the objective quantification of these alterations remains a challenge. Clinical rating scales are commonly used in clinical practice, but have been proven prone to errors associated to the evaluator subjective perception. On the other hand, instrumental measurement of trunk acceleration can be exploited for an objective quantitative characterization of gait function, but it is not applied in routine clinical practice, because the resulting quantitative indexes have not been related to the clinically information, conventionally provided by the rating scales...
September 27, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28987900/cardiorespiratory-responses-to-pool-floor-walking-in-people-post-stroke
#9
Brenda Jeng, Takuto Fujii, Hyosok Lim, Konstantinos Vrongistinos, Taeyou Jung
OBJECTIVE: To compare energy expenditure between pool floor walking (PFW) and overground walking (OW) in people post-stroke. DESIGN: Cross-sectional study. SETTING: University-based therapeutic exercise facility. PARTICIPANTS: 14 community-dwelling individuals post-stroke (5.57±3.57 years post-stroke) and 14 healthy adults, age- and gender-matched (aged 58.00±15.51, men to women ratio of 9:5) participated in the study...
October 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28987764/comparing-the-effects-of-adapting-to-a-weight-on-one-leg-during-treadmill-and-overground-walking-a-pilot-study
#10
Gabriela Lopes Gama, Douglas N Savin, Taylor Keenan, Sandy McCombe Waller, Jill Whitall
BACKGROUND: Locomotor adaptation has been suggested as a way to improve gait symmetry in individuals post-stroke. Most perturbation methods utilize costly, specialized equipment. The use of a unilateral leg weight may provide a low cost, clinically translatable alternative. Furthermore, previous studies have suggested that adaptation context may affect movement outcomes. The purpose of this study was to assess the ability of a unilaterally applied ankle weight to drive locomotor adaptation and determine the effect of context (treadmill versus overground) in young, non-disabled participants...
September 23, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28986199/vascular-parkinsonism-in-a-tertiary-care-stroke-prevention-clinic-and-the-development-of-a-new-screening-strategy
#11
Herbert A Manosalva, Fabricio Pio, Thomas Jeerakathil, Maher Saqqur, Richard Camicioli, Oksana Suchowersky
OBJECTIVES: To determine the prevalence of vascular parkinsonism (VasP) in a stroke prevention clinic (SPC). BACKGROUND: VasP can be defined by an onset of parkinsonism with prominent gait problems occurring within 1 year of stroke. METHODS: We created a screening strategy based on the Tanner Questionnaire (TQ), a validated scale for parkinsonism, and the creation of a 4-point Five-Minute Assessment Scale (FMAS) operationalizing Zijlmans' criteria for the diagnosis of VasP...
October 3, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28980355/cortical-disconnection-of-the-ipsilesional-primary-motor-cortex-is-associated-with-gait-speed-and-upper-extremity-motor-impairment-in-chronic-left-hemispheric-stroke
#12
Denise M Peters, Julius Fridriksson, Jill C Stewart, Jessica D Richardson, Chris Rorden, Leonardo Bonilha, Addie Middleton, Ezequiel Gleichgerrcht, Stacy L Fritz
Advances in neuroimaging have enabled the mapping of white matter connections across the entire brain, allowing for a more thorough examination of the extent of white matter disconnection after stroke. To assess how cortical disconnection contributes to motor impairments, we examined the relationship between structural brain connectivity and upper and lower extremity motor function in individuals with chronic stroke. Forty-three participants [mean age: 59.7 (±11.2) years; time poststroke: 64.4 (±58.8) months] underwent clinical motor assessments and MRI scanning...
October 5, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28978746/flagellar-swimming-in-viscoelastic-fluids-role-of-fluid-elastic-stress-revealed-by-simulations-based-on-experimental-data
#13
Chuanbin Li, Boyang Qin, Arvind Gopinath, Paulo E Arratia, Becca Thomases, Robert D Guy
Many important biological functions depend on microorganisms' ability to move in viscoelastic fluids such as mucus and wet soil. The effects of fluid elasticity on motility remain poorly understood, partly because the swimmer strokes depend on the properties of the fluid medium, which obfuscates the mechanisms responsible for observed behavioural changes. In this study, we use experimental data on the gaits of Chlamydomonas reinhardtii swimming in Newtonian and viscoelastic fluids as inputs to numerical simulations that decouple the swimmer gait and fluid type in order to isolate the effect of fluid elasticity on swimming...
October 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28976249/walking-and-balance-ability-gain-from-two-types-of-gait-intervention-in-adult-patients-with-chronic-hemiplegic-stroke-a-pilot-study
#14
Yoon-Hee Choi, Jung-Doo Kim, Jun-Ho Lee, Yong-Jun Cha
This study examined whether the walking and balance ability of adult patients with chronic hemiplegic stroke are associated differentially with the degree of gain after 2 types of gait intervention. Twenty-four subjects with hemiplegic stroke were enrolled in this randomized study. Each subject participated in one of two gait intervention strategies: gait training with auditory feedback caused by active weight bearing on the paralyzed side (experimental group; EG) or general gait intervention over the ground (control group; CG)...
October 4, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28963980/virtual-obstacle-crossing-reliability-and-differences-in-stroke-survivors-who-prospectively-experienced-falls-or-no-falls
#15
Michiel Punt, Sjoerd M Bruijn, Harriet Wittink, Ingrid G van de Port, Gijs Wubbels, Jaap H van Dieën
INTRODUCTION: Stroke survivors often fall during walking. To reduce fall risk, gait testing and training with avoidance of virtual obstacles is gaining popularity. However, it is unknown whether and how virtual obstacle crossing is associated with fall risk. AIM: The present study assessed whether obstacle crossing characteristics are reliable and assessed differences in stroke survivors who prospectively experienced falls or no falls. METHOD: We recruited twenty-nine community dwelling chronic stroke survivors...
September 15, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28958663/improving-real-world-walking-habits-after-stroke-requires-behavioural-change-techniques-not-just-exercise-and-gait-training-synopsis
#16
Prudence Plummer
No abstract text is available yet for this article.
October 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28950803/changes-in-gait-and-plantar-foot-loading-upon-using-vibrotactile-wearable-biofeedback-system-in-patients-with-stroke
#17
Christina Zong-Hao Ma, Yong-Ping Zheng, Winson Chiu-Chun Lee
BACKGROUND: Patients with stroke walk with excessive foot inversion at the affected side, which may disturb their balance and gait. OBJECTIVES: This study aimed to investigate the effects of instant biofeedback of plantar force at the medial and lateral forefoot regions on gait and plantar foot loading in patients with stroke. METHODS: A total of eight patients with hemiplegic stroke, who had flexible rearfoot varus deformity at the affected side, participated in this study...
September 27, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28949369/determining-the-cut-off-value-for-knee-extensor-strength-for-identifying-independence-in-gait-in-chronic-stroke-survivors
#18
Naoki Akazawa, Naomi Okawa, Kimiyuki Tamura, Hideki Moriyama
OBJECTIVE: To determine the cut-off values for knee extensor strength on the paretic and non-paretic sides and both sides combined for identifying independence in gait in chronic stroke survivors. DESIGN: Cross-sectional study. PATIENTS: Sixty chronic stroke survivors. METHODS: Functional Independence Measure (FIM) gait scores were measured, and the participants were allocated to the independent group (FIM gait score 6 or 7) or the dependent group (FIM gait score 1-5)...
September 26, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28949281/effect-of-activity-based-mirror-therapy-on-lower-limb-motor-recovery-and-gait-in-stroke-a-randomised-controlled-trial
#19
Kamal Narayan Arya, Shanta Pandian, Vikas Kumar
OBJECTIVE: To determine the effect of activity-based mirror therapy (MT) on motor recovery and gait in chronic poststroke hemiparetic subjects. DESIGN: A randomised, controlled, assessor-blinded trial. SETTING: Rehabilitation institute. PARTICIPANTS: Thirty-six chronic poststroke (15.89 ± 9.01 months) hemiparetic subjects (age: 46.44 ± 7.89 years, 30 men and functional ambulation classification of median level 3)...
September 26, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28949120/autonomous-rehabilitation-at-stroke-patients-home-for-balance-and-gait-safety-usability-and-compliance-of-a-virtual-reality-system
#20
Jeremia P Held, Begoña Ferrer, Renato Mainetti, Alexander Steblin, Benjamin Hertler, Alberto Moreno-Conde, Alvaro Dueñas, Marta Pajaro, Carlos L-Parra-Calderón, Eloisa Vargiu, Maria J Zarco, Maria Barrera, Carmen Echevarria, Francisco Jódar-Sánchez, Andreas R Luft, Nunzio A Borghese
BACKGROUND: New technologies, such as telerehabilitation and gaming devices offer the possibility for patients to train at home. This opens the challenge of safety for the patient as he is called to exercise neither with a therapist on the patients' side nor with a therapist linked remotely to supervise the sessions. AIM: To study the safety, usability and patient acceptance of an autonomous telerehabilitation system for balance and gait (the REWIRE platform) in the patients home...
September 25, 2017: European Journal of Physical and Rehabilitation Medicine
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