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psychosis evaluation

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https://www.readbyqxmd.com/read/28648915/long-term-course-of-negative-symptom-subdomains-and-relationship-with-outcome-in-patients-with-a-psychotic-disorder
#1
Annemarie P M Stiekema, Md Atiqul Islam, Edith J Liemburg, Stynke Castelein, Edwin R van den Heuvel, Jaap van Weeghel, André Aleman, Richard Bruggeman, Lisette van der Meer
BACKGROUND: The longitudinal course of the negative symptoms subdomains social amotivation (SA) and expressive deficits (ED) remains largely unknown. We investigated i) the longitudinal course of SA and ED subdomain scores, ii) whether subgroups based on the course of SA and ED subdomain scores could be identified, iii) whether baseline SA and ED subdomain scores were related to functioning and quality of life six years later and iv) the longitudinal relationship between subgroups and outcomes...
June 22, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28648914/psychometrics-of-social-cognitive-measures-for-psychosis-treatment-research
#2
Charlie A Davidson, Rebecca Lesser, Lori T Parente, Joanna M Fiszdon
Social cognition represents an important treatment target, closely linked to everyday social function. While a number of social cognitive interventions have recently been developed, measures used to evaluate these treatments are only beginning to receive psychometric scrutiny. Study goals were to replicate recently-published psychometrics for several social cognitive measures, and to provide information for additional social cognitive measures not included in recent reports. Forty-eight outpatients with psychotic-spectrum disorders completed measures of emotion perception, theory of mind, and attributional bias on two occasions, one month apart...
June 22, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28645887/perspectives-of-family-members-on-using-technology-in-youth-mental-health-care-a-qualitative-study
#3
Shalini Lal, Winnie Daniel, Lysanne Rivard
BACKGROUND: Information and communication technologies (ICTs) are increasingly recognized as having an important role in the delivery of mental health services for youth. Recent studies have evaluated young people's access and use of technology, as well as their perspectives on using technology to receive mental health information, services, and support; however, limited attention has been given to the perspectives of family members in this regard. OBJECTIVE: The aim of this study was to explore the perspectives of family members on the use of ICTs to deliver mental health services to youth within the context of specialized early intervention for a first-episode psychosis (FEP)...
June 23, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28636574/early-intervention-programme-for-patients-with-psychotic-disorders-in-sveti-ivan-psychiatric-hospital-ripepp-sociodemographic-and-baseline-characteristics-of-the-participants
#4
Branka Restek-Petrović, Ana Majdančić, Sven Molnar, Majda Grah, Ena Ivezić, Igor Filipčić, Anamarija Bogović, Vladimir Grošić, Nina Mayer, Slobodanka Kezić, Irena Pavlović
BACKGROUND: Psychiatric hospital "Sveti Ivan" in Zagreb, Croatia, offers an outpatient Early intervention programme for patients with psychotic disorders (RIPEPP), consisting of psychoeducational workshops and group psychodynamic psychotherapy. The aim of this study was to describe sociodemographic and baseline characteristics of the participants, in order to provide better understanding of this population, and to assist with the development of more effective therapeutic approaches. SUBJECTS AND METHODS: Since 2008, a total of 245 patients with first episodes of psychosis and their family members participated in the programme...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28636201/an-exploration-of-the-relationship-between-use-of-safety-seeking-behaviours-and-psychosis-a-systematic-review-and-meta-analysis
#5
Sarah Tully, Adrian Wells, Anthony P Morrison
Safety-seeking behaviours are responses employed to protect against perceived threat. In relation to anxiety disorders, safety-seeking behaviours have been implicated in both the formation and maintenance of distress. Several studies have highlighted similar findings in relation to psychosis; however, this literature has not yet been synthesized. This review is, therefore, being conducted in order to synthesize the literature on safety seeking in people with psychosis to increase the understanding of this relationship...
June 21, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28628791/recent-life-events-and-psychosis-the-role-of-childhood-adversities
#6
Giovanni Mansueto, Carlo Faravelli
Life events are commonly reported to be related to psychosis. However, less attention has been given to the role that recent events play on psychosis, in relation to exposure to childhood adversity. The current study aimed to evaluate the relationship between recent events and psychosis, taking into account the role of early adversities. 78 psychotic patients and 156 controls were enrolled. Childhood adversity was evaluated using a validated semi-structured interview and the Childhood Experience of Care and Abuse Questionnaire...
June 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28622570/the-role-of-premorbid-personality-and-social-cognition-in-suicidal-behaviour-in-first-episode-psychosis-a-one-year-follow-up-study
#7
Manuel Canal-Rivero, J D Lopez-Moriñigo, M L Barrigón, S Perona-Garcelán, C Jimenez-Casado, A S David, J E Obiols-Llandrich, M Ruiz-Veguilla
BACKGROUND: High suicide attempt (SA) rates have been reported in first-episode psychosis (FEP) patients, particularly during the first year after the illness onset. Despite previous studies establishing several risk factors for suicidal behaviour in FEP, premorbid personality and social cognition have not been sufficiently investigated to date. OBJECTIVE: To test whether personality traits and social cognition are associated with SAs in FEP over a 12-month follow-up...
May 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28614301/microglia-dependent-synapse-loss-in-type-i-interferon-mediated-lupus
#8
Allison R Bialas, Jessy Presumey, Abhishek Das, Cees E van der Poel, Peter H Lapchak, Luka Mesin, Gabriel Victora, George C Tsokos, Christian Mawrin, Ronald Herbst, Michael C Carroll
Systemic lupus erythematosus (SLE) is an incurable autoimmune disease characterized by autoantibody deposition in tissues such as kidney, skin and lungs. Notably, up to 75% of patients with SLE experience neuropsychiatric symptoms that range from anxiety, depression and cognitive impairment to seizures and, in rare cases, psychosis-collectively this is referred to as central nervous system (CNS) lupus. In some cases, certain autoantibodies, such as anti-NMDAR or anti-phospholipid antibodies, promote CNS lupus...
June 14, 2017: Nature
https://www.readbyqxmd.com/read/28613973/the-association-of-cannabis-use-on-inpatient-psychiatric-hospital-outcomes
#9
Melanie Rylander, Helena R Winston, Haley Medlin, Madelyne Hull, Abraham Nussbaum
BACKGROUND: The associations between cannabis use and psychosis are well documented in numerous studies. There is a need to evaluate the impact of cannabis use on inpatient psychiatric utilization and outcomes. OBJECTIVES: To evaluate the impact of cannabis use on psychiatric hospital outcomes. METHODS: This study was conducted between April 20, 2015 and October 20, 2015. All patients (n = 120) admitted to Denver Health with psychotic symptoms were administered a urine toxicology screening testing for the presence of 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol (THC-COOH, the active metabolite of cannabis)...
June 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28612111/probable-mechanisms-involved-in-the-antipsychotic-like-activity-of-methyl-jasmonate-in-mice
#10
Olajide S Annafi, Oritoke M Aluko, Anthony T Eduviere, Osarume Omorogbe, Solomon Umukoro
Psychosis is a chronic neuropsychiatric disorder that affects millions of individuals worldwide and impairs the quality of life and productivity of the patients. The clinical efficacy of antipsychotic drugs has been compromised by adverse effects, relapse, and therapeutic failures, thus necessitating search for alternative agents. Methyl jasmonate (MJ) is a bioactive compound reported to have beneficial effects in various neurological disorders. This study was undertaken to investigate the antipsychotic-like effects of MJ in mice...
June 13, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28608852/risk-of-psychosis-in-refugees-a-literature-review
#11
REVIEW
J Dapunt, U Kluge, A Heinz
Conflicts and precarious living conditions resulted in the arrival of large numbers of refugees in Europe and especially in Germany. Evidence suggests that immigrant populations are at elevated risk of psychotic disorders. Considering the traumatic pre- and post-migratory adversities refugees may have encountered, people granted refugee status may even be more susceptible to psychosis than non-refugee migrants. The aim of this literature review is to summarise and interpret recent research on the incidence or prevalence of psychotic disorders in refugees, additionally focusing on the aspects of gender and Middle Eastern provenance...
June 13, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28602144/antipsychotic-treatment-experiences-of-fully-recovered-service-users
#12
Jone Bjornestad, Larry Davidson, Inge Joa, Tor Ketil Larsen, Wenche Ten Velden Hegelstad, Johannes Langeveld, Marius Veseth, Ingrid Melle, Jan Olav Johannessen, Kolbjorn Bronnick
BACKGROUND: There is lack of long-term controlled studies evaluating treatment effects of antipsychotic medication. A complete investigation should include the service user perspective. AIMS: To investigate experiences of clinically recovered service users of antipsychotic medications during and after a first episode of psychosis. METHOD: We used a thematic analytic approach within an interpretative-phenomenological framework. 20 clinically recovered service users were interviewed...
June 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28598957/childhood-adversity-cortisol-levels-and-psychosis-a-retrospective-investigation
#13
Carlo Faravelli, Giovanni Mansueto, Sara Palmieri, Carolina Lo Sauro, Francesco Rotella, Francesco Pietrini, Giulia Fioravanti
Although it has been proposed that the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis may act as a possible pathway linking early life stress to psychosis, this relationship has not yet been fully confirmed. This study aimed to investigate the relationship between childhood adversity (CA), cortisol levels, and psychosis. Eighty-five patients with psychosis and 170 control subjects were enrolled in the study. CA was evaluated using the Florence Psychiatric Interview, and Childhood Experience of Care and Abuse Questionnaire...
June 8, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28596909/developing-a-scalable-training-model-in-global-mental-health-pilot-study-of-a-video-assisted-training-program-for-generalist-clinicians-in-rural-nepal
#14
B Acharya, J Tenpa, M Basnet, S Hirachan, P Rimal, N Choudhury, P Thapa, D Citrin, S Halliday, S B Swar, C van Dyke, B Gauchan, B Sharma, E Hung, M Ekstrand
BACKGROUND: In low- and middle-income countries, mental health training often includes sending few generalist clinicians to specialist-led programs for several weeks. Our objective is to develop and test a video-assisted training model addressing the shortcomings of traditional programs that affect scalability: failing to train all clinicians, disrupting clinical services, and depending on specialists. METHODS: We implemented the program -video lectures and on-site skills training- for all clinicians at a rural Nepali hospital...
2017: Global Mental Health
https://www.readbyqxmd.com/read/28595088/the-relationship-between-cannabis-use-and-cortisol-levels-in-youth-at-ultra-high-risk-for-psychosis
#15
Emily E Carol, Robert L Spencer, Vijay A Mittal
Recent studies have posited a relationship between cannabis use and the biological stress system, but this critical relationship has not been evaluated during the ultra high-risk (UHR) period immediately preceding the onset of psychotic disorders. Salivary cortisol samples were collected on 46 UHR and 29 control adolescents; these individuals were assessed for current cannabis use with a urine panel and self-report. UHR participants where separated into two groups: Current Cannabis Use (UHR-CU) and No Current Cannabis Use (UHR-NC)...
May 30, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28594303/self-inflicted-enucleations-clinical-features-of-seven-cases
#16
Mamta Shah, Lucy Sun, Solly Elmann, Ivan Vrcek, Ronald Mancini, Hee Joon Kim, Jacqueline Carrasco, Roman Shinder
We report the clinical presentation, radiography, and management outcomes of autoenucleations (AE). Charts of 7 patients evaluated at 4 institutions with AE were reviewed. Four males and three females had a mean age of 50 years (range 26-72 years). The etiologies were psychosis secondary to underlying mental illness (6, 88%) and substance use (1, 12%), and the mechanism was largely blunt digital injury (6, 88%). Three (43%) AE patients suffered bilateral enucleations. Common concomitant injuries included eyelid lacerations (5, 71%) and optic nerve avulsion (3, 43%)...
June 2017: Orbit
https://www.readbyqxmd.com/read/28589494/the-accuracy-of-the-ados-2-in-identifying-autism-among-adults-with-complex-psychiatric-conditions
#17
Brenna B Maddox, Edward S Brodkin, Monica E Calkins, Kathleen Shea, Katherine Mullan, Jack Hostager, David S Mandell, Judith S Miller
The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Module 4 is considered a "gold-standard" instrument for diagnosing autism spectrum disorder (ASD) in adults. Although the ADOS-2 shows good sensitivity and specificity in lab-based settings, it is unknown whether these results hold in community clinics that serve a more psychiatrically impaired population. This study is the first to evaluate the diagnostic accuracy of the ADOS-2 among adults in community mental health centers (n = 75)...
June 6, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28584649/adherence-to-nice-guidance-on-lifestyle-advice-for-people-with-schizophrenia-a-survey
#18
Lizzie Swaby, Daniel Hind, Rebecca Gossage-Worrall, David Shiers, Jonathan Mitchell, Richard I G Holt
Aims and method The STEPWISE trial (STructured lifestyle Education for People WIth SchizophrEnia, schizoaffective disorder and first episode psychosis) is currently evaluating a lifestyle education programme in addition to usual care. However, it is difficult to define what constitutes 'usual care'. We aimed to define 'usual care' for lifestyle management in people with schizophrenia, schizoaffective disorder and first-episode psychosis in STEPWISE study sites. Ten National Health Service (NHS) mental health trusts participated in a bespoke survey based on the National Institute for Health and Care Excellence (NICE) guidance...
June 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28583103/in-patient-costs-of-agitation-and-containment-in-a-mental-health-catchment-area
#19
Antoni Serrano-Blanco, Maria Rubio-Valera, Ignacio Aznar-Lou, Luisa Baladón Higuera, Karina Gibert, Alfredo Gracia Canales, Lisette Kaskens, José Miguel Ortiz, Luis Salvador-Carulla
BACKGROUND: There is a scarce number of studies on the cost of agitation and containment interventions and their results are still inconclusive. We aimed to calculate the economic consequences of agitation events in an in-patient psychiatric facility providing care for an urban catchment area. METHODS: A mixed approach combining secondary analysis of clinical databases, surveys and expert knowledge was used to model the 2013 direct costs of agitation and containment events for adult inpatients with mental disorders in an area of 640,572 adult inhabitants in South Barcelona (Spain)...
June 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28572021/death-certificates-data-and-causes-of-death-in-patients-with-parkinsonism
#20
Mariana Moscovich, Gabriela Boschetti, Adriana Moro, Helio A G Teive, Anhar Hassan, Renato P Munhoz
INTRODUCTION: Assessment of variables related to mortality in Parkinson disease (PD) and other parkinsonian syndromes relies, among other sources, on accurate death certificate (DC) documentation. We assessed the documentation of the degenerative disorder on DCs and evaluated comorbidities and causes of death among parkinsonian patients. METHODS: Demographic and clinical data were systematically and prospectively collected on deceased patients followed at a tertiary movement disorder clinic...
May 26, 2017: Parkinsonism & related Disorders
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