keyword
MENU ▼
Read by QxMD icon Read
search

psychosis evaluation

keyword
https://www.readbyqxmd.com/read/28922588/persistent-negative-symptoms-in-first-episode-psychosis-early-cognitive-and-social-functioning-correlates-and-differences-between-early-and-adult-onset
#1
Olga Puig, Immaculada Baeza, Elena de la Serna, Bibiana Cabrera, Gisela Mezquida, Miquel Bioque, Antonio Lobo, Ana González-Pinto, Mara Parellada, Iluminada Corripio, Eduard Vieta, Julio Bobes, Judith Usall, Fernando Contreras, Manuel J Cuesta, Miquel Bernardo, Josefina Castro-Fornieles, The PEPs Group
OBJECTIVE: To characterize the early cognitive and social functioning characteristics of a sample of first-episode psychosis patients with and without persistent negative symptoms (PNS) and to examine the prevalence and cognitive and functional correlates of PNS in patients with early-onset versus adult-onset first-episode psychosis. METHODS: Participants were 235 patients with first-episode psychosis (51 early-onset, 184 adult-onset) and 240 healthy controls from a multicenter longitudinal study (recruited between 2009 and 2011)...
September 12, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28911048/what-can-different-motor-circuits-tell-us-about-psychosis-an-rdoc-perspective
#2
Vijay A Mittal, Jessica A Bernard, Georg Northoff
Signs of motor dysfunction are evidenced across a range of psychiatric disorders including schizophrenia. Historically, these features have been neglected but emerging theoretical and methodological advancements have shed new light on the utility of considering movement abnormalities. Indeed, the National Institute of Mental Health Research Domain Criteria initiative has recently met to develop a Motor Systems Domain. This reflects a growing appreciation for the enhanced reliability and validity that can come along with evaluating disturbances relevant to psychiatric illnesses from multiple levels of analysis, and conceptualizing these domains with respect to the complexity of their role in a broader integrated system (ie, weighing contributions and interactions between the cognitive, affective, and motor domains)...
September 1, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28910597/predictors-of-change-in-social-networks-support-and-satisfaction-following-a-first-episode-psychosis-a-cohort-study
#3
Laoise Renwick, Liz Owens, John Lyne, Brian O'Donoghue, Eric Roche, Jonathan Drennan, Ann Sheridan, Mark Pilling, Eadbhard O'Callaghan, Mary Clarke
BACKGROUND: Diminished social networks are common in psychosis but few studies have measured these comprehensively and prospectively to determine how networks and support evolve during the early phase. There is little information regarding perceived support in the early phase of illness. The aim of this study was to describe social support, networks and perceived satisfaction, explore the clinical correlates of these outcomes and examine whether phases of untreated psychosis are linked with social network variables to determine potential opportunities for intervention...
August 30, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28901206/rural-urban-differences-in-accessing-mental-health-treatment-in-patients-with-psychosis
#4
Jagadisha Thirthalli, K Shanivaram Reddy, Manoranjitha Kare, Soumitra Das, B N Gangadhar
BACKGROUND: Delay in accessing psychiatric treatment has considerable influence on the outcome of psychoses. Systematic studies examining the source of the delay are lacking in India. In this article, we examine rural-urban differences regarding delay in accessing psychiatric care in patients with psychosis, an issue which was hitherto not studied. AIMS: To evaluate the rural-urban differences in treatment seeking among patients with psychosis. METHODS: Patients with psychotic disorders who presented to the outpatient department of an academic psychiatric institute for the first time ( n = 551) were interviewed using a semi-structured interview tool to assess the date of onset of illness...
September 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28900690/community-treatment-orders-and-social-outcomes-for-patients-with-psychosis-a-48-month-follow-up-study
#5
Francis Vergunst, Jorun Rugkåsa, Constantinos Koshiaris, Judit Simon, Tom Burns
PURPOSE: Community treatment orders (CTOs) are widely used internationally despite a lack of evidence supporting their effectiveness. Most effectiveness studies are relatively short (12-months or less) and focus on clinical symptoms and service data, while a little attention is given to patients' social outcomes and broader welfare. We tested the association between the duration of CTO intervention and patients' long-term social outcomes. METHODS: A sub-sample (n = 114) of community-based patients from the Oxford Community Treatment Order Evaluation Trial (OCTET) were interviewed 48 months after randomisation...
September 12, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28899881/tet1-overexpression-leads-to-anxiety-like-behavior-and-enhanced-fear-memories-via-the-activation-of-calcium-dependent-cascade-through-egr1-expression-in-mice
#6
Wookbong Kwon, Hyeng-Soo Kim, Jain Jeong, Yonghun Sung, Minjee Choi, Song Park, Jinhee Lee, Soyoung Jang, Sung Hyun Kim, Sanggyu Lee, Myoung Ok Kim, Zae Young Ryoo
Ten-eleven translocation methylcytosine dioxygenase 1 (Tet1) initiates DNA demethylation by converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) at CpG-rich regions of genes, which have key roles in adult neurogenesis and memory. In addition, the overexpression of Tet1 with 5-hmC alteration in patients with psychosis has also been reported, for instance in schizophrenia and bipolar disorders. The mechanism underlying Tet1 overexpression in the brain; however, is still elusive. In the present study, we found that Tet1-transgenic (Tet1-TG) mice displayed abnormal behaviors involving elevated anxiety and enhanced fear memories...
September 12, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28892069/reduction-of-plasma-glutathione-in-psychosis-associated-with-schizophrenia-and-bipolar-disorder-in-translational-psychiatry
#7
L G Nucifora, T Tanaka, L N Hayes, M Kim, B J Lee, T Matsuda, F C Nucifora, T Sedlak, R Mojtabai, W Eaton, A Sawa
The establishment of mechanism-driven peripheral markers is important for translational psychiatry. Many groups, including ours, have addressed molecular alterations in peripheral tissues in association with symptomatic changes in major illnesses. Oxidative stress is implicated in the pathophysiology of schizophrenia (SZ) and bipolar disorder (BP) through studies of patient peripheral tissues and animal models. Although the relationship between peripheral changes and brain pathology remain elusive, oxidative stress may bridge such translational efforts...
August 22, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28890132/motor-abnormalities-in-first-episode-psychosis-patients-and-long-term-psychosocial-functioning
#8
Manuel J Cuesta, Elena García de Jalón, M Sol Campos, Lucía Moreno-Izco, Ruth Lorente-Omeñaca, Ana M Sánchez-Torres, Víctor Peralta
Motor abnormalities (MAs) are highly prevalent in patients with first-episode psychosis both before any exposure and after treatment with antipsychotic drugs. However, the extent to which these abnormalities have predictive value for long-term psychosocial functioning is unknown. One hundred antipsychotic-naive first-episode psychosis (FEP) patients underwent extensive motor evaluation including catatonic, parkinsonism, dyskinesia, akathisia and neurological soft signs. Patients were assessed at naïve state and 6months later...
September 7, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28888362/risk-factors-for-increased-duration-of-untreated-psychosis-results-from-the-face-sz-dataset
#9
G Fond, L Boyer, M Andrianarisoa, O Godin, L Brunel, E Bulzacka, N Coulon, P M Llorca, F Berna, B Aouizerate, D Capdevielle, T D'Amato, C Dubertret, J Dubreucq, C Faget, F Gabayet, J Mallet, D Misdrahi, R Rey, R Richieri, P Roux, C Passerieux, A Schandrin, A M Tronche, P Vidailhet, M Leboyer, F Schürhoff
OBJECTIVES: Reducing the duration of untreated psychosis (DUP) may improve the prognosis of schizophrenia. This study investigated the prevalence, and associated risk factors, of long DUP in a large, non-selected sample of community-dwelling schizophrenia patients (SZ). METHOD: 478 community-dwelling stable SZ participants (122 women and 356 men; mean age 32.37±9.86years) were recruited between 2010 and 2016. The mean retrospective DUP was evaluated from both patient and family reports, as well as hospital/psychiatrists records...
September 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28888358/prediction-of-self-stigma-in-early-psychosis-3-year-follow-up-of-the-randomized-controlled-trial-on-extended-early-intervention
#10
Ryan Wui Hang Ho, Wing Chung Chang, Vivian Wing Yan Kwong, Emily Sin Kei Lau, Gloria Hoi Kei Chan, Olivia Tsz Ting Jim, Christy Lai Ming Hui, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Eric Yu Hai Chen
BACKGROUND: Self-stigma represents a major barrier to recovery in people with psychotic disorders but is understudied in early illness stage. Longitudinal investigation of prediction for self-stigma is scarce and none is conducted in early psychosis. We aimed to prospectively examine baseline predictors of self-stigma in early psychosis patients in the context of a 3-year follow-up of a randomized-controlled trial (RCT) comparing 1-year extension of early intervention (EI) with step-down psychiatric care for first-episode psychosis (FEP)...
September 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28882907/protocol-for-a-systematic-review-of-psychological-treatment-for-methamphetamine-use-an-analysis-of-methamphetamine-use-and-mental-health-symptom-outcomes
#11
Alexandra Stuart, Amanda L Baker, Jenny Bowman, Kristen McCarter, Alexandra Mary Janice Denham, Nicole Lee, Kim Colyvas, Adrian Dunlop
INTRODUCTION: People who use methamphetamine (MA) regularly, often experience symptoms of mental ill health associated with the use of the drug. These include symptoms of psychosis, depression, anxiety and also cognitive deficits. Accordingly, psychological treatments aim to reduce MA use and related problems, including symptoms of mental ill health. Although there has been a substantial body of research reporting on the evidence of effectiveness of psychological treatments for MA use, there is a paucity of research addressing the effectiveness of these treatments for coexisting symptoms of mental ill health...
September 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28875990/clinical-and-pre-clinical-evidence-for-functional-interactions-of-cannabidiol-and-%C3%AE-9-tetrahydrocannabinol
#12
Douglas L Boggs, Jacques D Nguyen, Daralyn Morgenson, Michael A Taffe, Mohini Ranganathan
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its psychotropic and mind-altering side effects for millennia. There has been growing attention in recent years on its potential therapeutic efficacy as municipalities and legislative bodies in the United States, Canada, and other countries grapple with enacting policy to facilitate the use of cannabis or its constituents for medical purposes. There are over 550 chemical compounds and over 100 phytocannabinoids isolated from cannabis, including Δ(9)-tetrahydrocannabinol (THC) and Cannabidiol (CBD)...
September 6, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28866713/elevated-hydroxylactam-of-hemopyrrole-level-in-urine-in-perpetrators-of-extremely-violent-acts-diagnosed-with-psychosis
#13
Janusz Heitzman, Paweł Gosek, Wojciech Lechowicz, Ryszard Wardeński, Tomasz Stępień
OBJECTIVES: Hydroxylactam of hemopyrrole (HPL) is an abnormal side product of porphyrin biosynthetic pathway, which may have a devastating impact on the behavior. The link between an aggressive behavior and an increased HPL level was postulated in the 1960s. Further researches concerning HPL brought contrary results and did not clarify its function and possible role in the pathogenesis of aggression. In our research we hypothesize that a heightened level of HPL may correspond to an extreme aggressive behavior in subjects diagnosed with psychosis...
June 18, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28857488/preliminary-study-of-higher-order-language-and-extralinguistic-impairments-in-individuals-with-high-clinical-risk-of-psychosis-and-first-episode-of-schizophrenia
#14
Agnieszka Pawełczyk, Magdalena Kotlicka-Antczak, Emila Łojek, Tomasz Pawełczyk
AIM: Higher-order language functions are associated with understanding indirect speech acts, lexical-semantic processes, the understanding and production of prosody, discourse production and comprehension. Only a few studies imply that language abnormalities may be present in individuals at ultra-high risk for psychosis (UHR) and first-episode of schizophrenia (FE). The purpose of this study was to test the presence of higher-order language dysfunctions in UHR and FE subjects using a standardized comprehensive test battery...
August 31, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28853004/sex-specific-issues-in-eating-disorders-a-clinical-and-psychopathological-investigation
#15
Stefano Valente, Giulia Di Girolamo, Martina Forlani, Anna Biondini, Paolo Scudellari, Diana De Ronchi, Anna Rita Atti
OBJECTIVE: To highlight the characteristics of eating disorders (ED) in males, with particular attention to sex-related clinical features and psychiatric co-morbidities. METHOD: Out of 280 persons, referred to our outpatients ED clinic between January 2011 and June 2014, 267 with complete information were included in this retrospective observational study. RESULTS: The men/women ratio was one to five (male 16.5% vs female 83.5%) with an increasing proportion of male patients over the years...
August 29, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28844436/psychosis-subgroups-differ-in-intrinsic-neural-activity-but-not-task-specific-processing
#16
Matthew E Hudgens-Haney, Lauren E Ethridge, Jennifer E McDowell, Sarah K Keedy, Godfrey D Pearlson, Carol A Tamminga, Matcheri S Keshavan, John A Sweeney, Brett A Clementz
Individuals with psychosis often show high levels of intrinsic, or nonspecific, neural activity, but attenuated stimulus-specific activity. Clementz et al. (2016) proposed that one subgroup of psychosis cases has accentuated intrinsic activity (Biotype-2's) and a different subgroup (Biotype-1's) has diminished intrinsic activity, with both groups exhibiting varying degrees of cognitive deficits. This model was studied by assessing neural activity in psychosis probands (N=105) during baseline and a 5second period in preparation for a pro-/anti-saccade task...
August 24, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28844432/do-trauma-focussed-psychological-interventions-have-an-effect-on-psychotic-symptoms-a-systematic-review-and-meta-analysis
#17
REVIEW
Rachel M Brand, Carla McEnery, Susan Rossell, Sarah Bendall, Neil Thomas
There is growing recognition of the relationship between trauma, posttraumatic stress disorder (PTSD) and psychosis. There may be overlaps in casual mechanisms involved in the development of PTSD and psychosis following traumatic or adverse events. Trauma-focussed treatments found to be effective in treating PTSD may therefore represent a new direction in the psychological treatment of psychosis. This systematic review examined the literature on trauma-focussed treatments conducted with people with schizophrenia spectrum or psychotic disorders to determine effects on psychotic symptoms...
August 24, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28844431/accounting-for-group-differences-in-study-retention-in-a-randomized-trial-of-specialized-treatment-for-first-episode-psychosis
#18
Kyaw Sint, Robert Rosenheck, Delbert G Robinson, Nina R Schooler, Patricia Marcy, John M Kane, Kim T Mueser, Haiqun Lin
BACKGROUND: Schizophrenia is a chronic disabling disorder for which current treatments are only partially effective. While the evaluation of novel interventions is a high priority, loss to follow-up is a major threat to validity. METHODS: Pattern mixture modeling is a statistical technique that incorporates information on patterns of retention that may bias comparisons between randomized treatment groups. This study used pattern mixture mixed model (PMMM) in the analysis of outcomes of a two-year cluster-randomized trial, the Recovery after an Initial Schizophrenia Episode-Early Treatment Program, which compared a coordinated specialty care intervention called NAVIGATE to usual community care (CC)...
August 24, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28841756/gastroschisis-in-europe-a-case-malformed-control-study-of-medication-and-maternal-illness-during-pregnancy-as-risk-factors
#19
Joanne E Given, Maria Loane, Ester Garne, Vera Nelen, Ingeborg Barisic, Hanitra Randrianaivo, Babak Khoshnood, Awi Wiesel, Anke Rissmann, Catherine Lynch, Amanda J Neville, Anna Pierini, Marian Bakker, Kari Klungsoyr, Anna Latos Bielenska, Clara Cavero-Carbonell, Marie-Claude Addor, Natalya Zymak-Zakutnya, David Tucker, Helen Dolk
BACKGROUND: Gastroschisis, a congenital anomaly of the abdomen, is associated with young maternal age and has increased in prevalence in many countries. Maternal illness and medication exposure are among environmental risk factors implicated in its aetiology. METHODS: A population-based case-malformed control study was conducted using data from 18 European congenital anomaly registries, with information on first trimester medication use, covering 8 million births 1995-2012...
August 25, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28827860/psychiatric-morbidity-in-the-community-a-population-based-study-from-kerala
#20
K S Shaji, D Raju, V Sathesh, P Krishnakumar, Varghese P Punnoose, P S Kiran, B S Mini, Shibu Kumar, P K Anish, Ganga G Kaimal, Lekshmy Gupthan, T P Sumesh, U G Nikhil, Nisha Cyriac, M D Vinod, R Prasad Kumar, Ramesh Chandran, P P Rejani, R Amrutha, Mahesh, T N Anand
BACKGROUND: Estimates of psychiatric morbidity in the community will help service development. Participation of trained nonspecialist health-care providers will facilitate scaling up of services in resource-limited settings. AIMS: This study aimed to estimate the prevalence of priority mental health problems in populations served by the District Mental Health Program (DMHP). SETTINGS AND DESIGN: This is a population-based cross-sectional survey...
April 2017: Indian Journal of Psychiatry
keyword
keyword
32259
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"