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Neural anatomy

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https://www.readbyqxmd.com/read/28516212/anatomical-visualization-of-neural-course-and-distribution-of-anterior-ascending-aortic-plexus
#1
Tomokazu Kawashima, Fumi Sato
The aim of this study was to document the detailed anatomy of neural course and distribution on the anterior ascending aorta, to identify the high and low density areas of the anterior ascending aortic plexus for further understandings in cardiovascular surgery. The embalmed hearts of 42 elderly individuals were submacroscopically and microscopically examined, after excluding any that were macroscopically abnormal. With its origins in the anterior ascending aortic plexus, the right coronary plexus substantially innervated the right coronary artery, the right atrium and ventricle, and the sinus node...
May 17, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28505166/brain-activation-of-semantic-category-based-grouping-in-multiple-identity-tracking-task
#2
Liuqing Wei, Xuemin Zhang, Chuang Lyu, Siyuan Hu, Zhen Li
Using Multiple Identity Tracking task and the functional magnetic resonance imaging (fMRI) technology, the present study aimed to isolate and visualize the functional anatomy of neural systems involved in the semantic category-based grouping process. Three experiment conditions were selected and compared: the category-based targets grouping (TG) condition, the targets-distractors grouping (TDG) condition and the homogenous condition. In the TG condition, observers could utilize the categorical distinction between targets and distractors, to construct a uniform presentation of targets, that is, to form a group of the targets to facilitate tracking...
2017: PloS One
https://www.readbyqxmd.com/read/28504548/the-lumbar-neural-foramen-and-transforaminal-epidural-steroid-injections-an-anatomic-review-with-key-safety-considerations-in-planning-the-percutaneous-approach
#3
Jacob C Mandell, Gregory J Czuczman, Glenn C Gaviola, Varand Ghazikhanian, Charles H Cho
OBJECTIVE: The purpose of this article is to review the anatomy of the lumbar neural foramen and to describe techniques of transforaminal epidural steroid injections with emphasis on safety. Rare cases of paraplegia have been reported. CONCLUSION: Although no consensus currently exists about which approach is the safest, knowledge of the foraminal anatomy is a key consideration when choosing a needle approach for transforaminal epidural steroid injections.
May 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28503544/update-on-foregut-molecular-embryology-and-role-of-regenerative-medicine-therapies
#4
REVIEW
Silvia Perin, Conor J McCann, Osvaldo Borrelli, Paolo De Coppi, Nikhil Thapar
Esophageal atresia (OA) represents one of the commonest and most severe developmental disorders of the foregut, the most proximal segment of the gastrointestinal (GI) tract (esophagus and stomach) in embryological terms. Of intrigue is the common origin from this foregut of two very diverse functional entities, the digestive and respiratory systems. OA appears to result from incomplete separation of the ventral and dorsal parts of the foregut during development, resulting in disruption of esophageal anatomy and frequent association with tracheo-oesophageal fistula...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28477340/a-neural-network-approach-for-fast-automated-quantification-of-dir-performance
#5
John Neylon, Yugang Min, Daniel A Low, Anand Santhanam
PURPOSE: A critical step in adaptive radiotherapy (ART) workflow is deformably registering the simulation CT with the daily or weekly volumetric imaging. Quantifying the deformable image registration accuracy under these circumstances is a complex task due to the lack of known ground-truth landmark correspondences between the source data and target data. Generating landmarks manually (using experts) is time-consuming, and limited by image quality and observer variability. While image similarity metrics (ISM) may be used as an alternative approach to quantify the registration error, there is a need to characterize the ISM values by developing a non-linear cost function and translate them to physical distance measures in order to enable fast, quantitative comparison of registration performance...
May 5, 2017: Medical Physics
https://www.readbyqxmd.com/read/28459522/information-integration-research-on-cumulative-effect-of-siqi-wuwei-and-guijing-in-traditional-chinese-medicine
#6
Xuming Yang, Mingyuan Qi, Qian Li, Li Chen, Zhongyi Yu, Lin Yang
OBJECTIVE: To study the morphological basis of the role of Siqi (cold as winter, cool as autumn, warm as spring, hot as summer), Wuwei (five flavors: sweet, pungent, salty, sour, and bitter), and Guijing (meridian tropism) through the use of information integration. METHODS: A 14C-2-deoxy-glucose autoradiography method was adopted to determine the overall impact of treatment with 39 herbs on functions of various tissues and organs. Data was measured at 4 hs after a single dose and following the last treatment of repeated doses for a week...
August 2016: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
https://www.readbyqxmd.com/read/28453669/image-based-correction-of-continuous-and-discontinuous-non-planar-axial-distortion-in-serial-section-microscopy
#7
Philipp Hanslovsky, John A Bogovic, Stephan Saalfeld
Motivation: Serial section microscopy is an established method for detailed anatomy reconstruction of biological specimen. During the last decade, high resolution electron microscopy (EM) of serial sections has become the de-facto standard for reconstruction of neural connectivity at ever increasing scales (EM connectomics). In serial section microscopy, the axial dimension of the volume is sampled by physically removing thin sections from the embedded specimen and subsequently imaging either the block-face or the section series...
May 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28445740/right-brain-left-brain-in-depressive-disorders-clinical-and-theoretical-implications-of-behavioral-electrophysiological-and-neuroimaging-findings
#8
REVIEW
Gerard E Bruder, Jonathan W Stewart, Patrick J McGrath
The right and left side of the brain are asymmetric in anatomy and function. We review electrophysiological (EEG and event-related potential), behavioral (dichotic and visual perceptual asymmetry), and neuroimaging (PET, MRI, NIRS) evidence of right-left asymmetry in depressive disorders. Recent electrophysiological and fMRI studies of emotional processing have provided new evidence of altered laterality in depressive disorders. EEG alpha asymmetry and neuroimaging findings at rest and during cognitive or emotional tasks are consistent with reduced left prefrontal activity in depressed patients, which may impair downregulation of amygdala response to negative emotional information...
April 23, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28441114/neural-circuitry-of-reward-prediction-error
#9
Mitsuko Watabe-Uchida, Neir Eshel, Naoshige Uchida
Dopamine neurons facilitate learning by calculating reward prediction error, or the difference between expected and actual reward. Despite two decades of research, it remains unclear how dopamine neurons make this calculation. Here we review studies that tackle this problem from a diverse set of approaches, from anatomy to electrophysiology to computational modeling and behavior. Several patterns emerge from this synthesis: that dopamine neurons themselves calculate reward prediction error, rather than inherit it passively from upstream regions; that they combine multiple separate and redundant inputs, which are themselves interconnected in a dense recurrent network; and that despite the complexity of inputs, the output from dopamine neurons is remarkably homogeneous and robust...
April 24, 2017: Annual Review of Neuroscience
https://www.readbyqxmd.com/read/28439772/neuromonitoring-in-endoscopic-and-robotic-thyroidectomy
#10
REVIEW
Gianlorenzo Dionigi, Hoon Yub Kim, Che-Wei Wu, Matteo Lavazza, Gabriele Materazzi, Celestino Pio Lombardi, Angkoon Anuwong, Ralph P Tufano
Intraoperative neuromonitoring (IONM) has proven effective for intraoperative verification of RLN function in the conventional thyroid surgery. However, no studies have performed a systematic evidence-based assessment of this novel health technology in endoscopic and robotic thyroidectomy. Evidence-based criteria were used in a systematic review of relevant literature for years 2000-2015. Four electronic databases (CENTRAL, MEDLINE, Cochrane and EMBASE) were used to retrieve relevant reports published from January 1, 2000 to September 1, 2016...
April 24, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28416459/the-error-of-broca-from-the-traditional-localizationist-concept-to-a-connectomal-anatomy-of-human-brain
#11
REVIEW
Hugues Duffau
Neurology, especially aphasiology, was mainly built on behavioral-structural correlations ("lesion method"). In this setting, Broca's area has been considered as the "speech area"; moreover, this observation led to localizationism. However, advances in brain mapping techniques, as functional neuroimaging and direct electrical stimulation in patients undergoing awake surgery for gliomas, has resulted in a paradigmatic shift regarding models of neural architecture. In fact, the brain is organized in distributed complex networks underpinning sensorimotor, visuospatial, language, cognitive and emotional functions...
April 14, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28413736/targeted-intraspinal-radiofrequency-ablation-for-lumbar-spinal-stenosis
#12
Robert E Jacobson, Michelle Granville, Jesse Hatgis DO
INTRODUCTION: By using a combination of magnetic resonance imaging (MRI) and computed tomography (CT) of the lumbar spine, it is possible to distinguish between spinal stenosis caused by bone compression and specific soft tissue epidural intraspinal lesions that cause localized spinal canal stenosis and neural compression. Examples include facet cysts and yellow ligament hypertrophy. Many of these patients are elderly with medical comorbidities that make open surgery problematic. MATERIALS & METHODS: This is a study of patients with predominantly soft tissue stenosis being treated with targeted intraspinal radiofrequency (RF) heat ablation...
March 10, 2017: Curēus
https://www.readbyqxmd.com/read/28408248/extraforaminal-compression-of-the-l5-nerve-an-anatomical-study-with-application-to-failed-posterior-decompressive-procedures
#13
R Shane Tubbs, Joe Iwanaga, Islam Aly, Marc D Moisi, David R Hanscom, Jens R Chapman, Marios Loukas, Rod J Oskouian
This anatomical study was performed to elucidate the pertinent foraminal and lateral L5 nerve anatomy to enhance our understanding of possible neurologic causes of failed decompression surgery. Persistent extraforaminal L5 nerve compression is a possible cause of persistent symptoms following lumbosacral surgery. The amount of extraforaminal space for the L5 ventral ramus was examined in fifty adult human skeletons (100 sides). Based on morphology, the specimens were then categorized (types I-IV) on the basis of the bony space available for the nerve at this location...
April 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28392009/genitourinary-and-gastrointestinal-co-morbidities-in-children-the-role-of-neural-circuits-in-regulation-of-visceral-function
#14
REVIEW
A P Malykhina, K E Brodie, D T Wilcox
OBJECTIVE: Pediatric lower urinary tract dysfunction (LUTD) is a common problem in childhood. Lower urinary tract symptoms in children include overactive bladder, voiding postponement, stress incontinence, giggle incontinence, and dysfunctional voiding. Gastrointestinal co-morbidities, including constipation or fecal incontinence, are commonly associated with lower urinary tract (LUT) symptoms in children, often reaching 22-34%. This review summarized the potential mechanisms underlying functional lower urinary and gastrointestinal co-morbidities in children...
June 15, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28391191/automatic-quality-assessment-of-echocardiograms-using-convolutional-neural-networks-feasibility-on-the-apical-four-chamber-view
#15
Amir Abdi, Christina Luong, Teresa Tsang, John Jue, Dale Hawley, Sarah Fleming, Kenneth Gin, Jody Swift, Robert Rohling, Purang Abolmaesumi
Echocardiography (echo) is a skilled technical procedure that depends on the experience of the operator. The aim of this work is to reduce user variability in data acquisition by automatically computing a score of echo quality for operator feedback. To do this, a deep convolutional neural network model, trained on a large set of samples, was developed for scoring apical four-chamber (A4C) echo. In this research, 6,916 end-systolic echo images were manually studied by an expert cardiologist and were assigned a score between 0 (not acceptable) and 5 (excellent)...
April 4, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28371793/ultrasound-standard-plane-detection-using-a-composite-neural-network-framework
#16
Hao Chen, Lingyun Wu, Qi Dou, Jing Qin, Shengli Li, Jie-Zhi Cheng, Dong Ni, Pheng-Ann Heng
Ultrasound (US) imaging is a widely used screening tool for obstetric examination and diagnosis. Accurate acquisition of fetal standard planes with key anatomical structures is very crucial for substantial biometric measurement and diagnosis. However, the standard plane acquisition is a labor-intensive task and requires operator equipped with a thorough knowledge of fetal anatomy. Therefore, automatic approaches are highly demanded in clinical practice to alleviate the workload and boost the examination efficiency...
March 30, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28355680/function-of-the-anterior-intermeniscal-ligament
#17
Trent M Guess, Swithin S Razu, Keiichi Kuroki, James L Cook
The function and importance of the anterior intermeniscal ligament (AIML) of the knee are not fully known. The purpose of this study was to evaluate the biomechanical and sensorimotor function of the AIML. Computational analysis was used to assess AIML and tibiomeniscofemoral biomechanics under combined translational and rotational loading applied during dynamic knee flexion-extension. Histologic and immunohistochemical examination was used to identify and characterize neural elements in the tissue. The computational models were created from anatomy and passive motion of two female subjects and histologic examinations were conducted on AIMLs retrieved from 10 fresh-frozen cadaveric knees...
March 29, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28350944/navigation-and-robotics-in-spinal-surgery-where-are-we-now
#18
Samuel C Overley, Samuel K Cho, Ankit I Mehta, Paul M Arnold
Spine surgery has experienced much technological innovation over the past several decades. The field has seen advancements in operative techniques, implants and biologics, and equipment such as computer-assisted navigation and surgical robotics. With the arrival of real-time image guidance and navigation capabilities along with the computing ability to process and reconstruct these data into an interactive three-dimensional spinal "map", so too have the applications of surgical robotic technology. While spinal robotics and navigation represent promising potential for improving modern spinal surgery, it remains paramount to demonstrate its superiority as compared to traditional techniques prior to assimilation of its use amongst surgeons...
March 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28350559/interventional-spine-considerations-for-dural-ectasia-in-a-patient-with-marfan-syndrome
#19
David J Kohns
For patients with Marfan syndrome who present with radicular low back pain, interventional spine providers should be familiar with dural ectasia with variable diffuse thinning of the posterior wall of the lumbar spine and sacrum. Providers should carefully weigh the risks and benefits of offering elective procedures because altered anatomy may put these patients at higher risk of dural puncture. Patient selection is essential because hydrostatic pressures and/or neural tension should also be considered as potential pain generators that may not be relieved by steroid injections...
March 27, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28346140/em-connectomics-reveals-axonal-target-variation-in-a-sequence-generating-network
#20
Jörgen Kornfeld, Sam E Benezra, Rajeevan T Narayanan, Fabian Svara, Robert Egger, Marcel Oberlaender, Winfried Denk, Michael A Long
The sequential activation of neurons has been observed in various areas of the brain, but in no case is the underlying network structure well understood. Here we examined the circuit anatomy of zebra finch HVC, a cortical region that generates sequences underlying the temporal progression of the song. We combined serial block-face electron microscopy with light microscopy to determine the cell types targeted by HVC(RA) neurons, which control song timing. Close to their soma, axons almost exclusively targeted inhibitory interneurons, consistent with what had been found with electrical recordings from pairs of cells...
March 27, 2017: ELife
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