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https://www.readbyqxmd.com/read/29352827/political-terrorism-and-affective-polarization-in-black-and-red-terrorists-in-italy-during-the-years-1968-1988
#1
Matteo Pacini, Icro Maremmani
Psychiatric evaluations of violent political crime were mostly performed on a case-by-case basis in a forensic environment, which made them unduly dependent on categories of presumed dangerousness and legal responsibility, rather than on a clinical definition of their mental status. In referring to such "clinical" definitions, the disorder we have in mind is not limited to the major, agitated psychotic manias or mixed states. The presence of a dominant temperament, or protracted hypomania, is enough by itself to explain an individual's engagement in a wide range of activities, not necessarily sociopathic or violent...
January 21, 2018: CNS Spectrums
https://www.readbyqxmd.com/read/29352754/providing-ethical-healthcare-in-resource-poor-environments
#2
Kenneth V Iserson
The ethics of providing health care in resource-poor environments is a complex topic. It implies two related questions: What can we do with the resources on hand? Of all the things we can do, which ones should we do? "Resource-poor" (i.e., resource-challenged, resource-constrained) environments are situations in which clinicians, organizations, or healthcare systems have the knowledge and skills, but not the means, to carry out highly effective and beneficial interventions. Determinants of a population's health often rely less on disease and injury management than on recognizing and meeting their basic needs...
January 19, 2018: HEC Forum: An Interdisciplinary Journal on Hospitals' Ethical and Legal Issues
https://www.readbyqxmd.com/read/29352607/integrated-lung-tissue-mechanics-one-piece-at-a-time-computational-modeling-across-the-scales-of-biology
#3
REVIEW
Kelly S Burrowes, Amin Iravani, Wendy Kang
The lung is a delicately balanced and highly integrated mechanical system. Lung tissue is continuously exposed to the environment via the air we breathe, making it susceptible to damage. As a consequence, respiratory diseases present a huge burden on society and their prevalence continues to rise. Emergent function is produced not only by the sum of the function of its individual components but also by the complex feedback and interactions occurring across the biological scales - from genes to proteins, cells, tissue and whole organ - and back again...
January 12, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29351325/impact-of-educational-interventions-on-adolescent-attitudes-and-knowledge-regarding-vaccination-a-pilot-study
#4
Kate Carolan, Joanna Verran, Matthew Crossley, James Redfern, Nicola Whitton, Martyn Amos
BACKGROUND: Current immunisation levels in England currently fall slightly below the threshold recommended by the World Health Organization, and the three-year trend for vaccination uptake is downwards. Attitudes towards vaccination can affect future decisions on whether or not to vaccinate, and this can have significant public health implications. Interventions can impact future vaccination decisions, and these interventions can take several forms. Relatively little work has been reported on the use of vaccination interventions in young people, who form the next generation of individuals likely to make vaccination decisions...
2018: PloS One
https://www.readbyqxmd.com/read/29351303/automated-inverse-optimization-facilitates-lower-doses-to-normal-tissue-in-pancreatic-stereotactic-body-radiotherapy
#5
Ivaylo B Mihaylov, Eric A Mellon, Raphael Yechieli, Lorraine Portelance
PURPOSE: Inverse planning is trial-and-error iterative process. This work introduces a fully automated inverse optimization approach, where the treatment plan is closely tailored to the unique patient anatomy. The auto-optimization is applied to pancreatic stereotactic body radiotherapy (SBRT). MATERIALS AND METHODS: The automation is based on stepwise reduction of dose-volume histograms (DVHs). Five uniformly spaced points, from 1% to 70% of the organ at risk (OAR) volumes, are used...
2018: PloS One
https://www.readbyqxmd.com/read/29350514/hospitalized-patients-and-family-members-preferences-for-real-time-transparent-access-to-their-hospital-records
#6
Michael J Waxman, Kurt Lozier, Lana Vasiljevic, Kira Novakofski, James Desemone, John O'Kane, Elizabeth M Dufort, David Wood, Ashar Ata, Louis Filhour, Richard J Blinkhorn
OBJECTIVES: To better understand patient satisfaction and perceived engagement with traditional hospital-based communication and to elicit patient preferences for health information technologies that would lead to improved satisfaction and engagement. STUDY DESIGN: We performed a mixed-methods study involving qualitative interviews followed by a survey of hospitalized patients and their family members at a single large academic medical center. METHODS: We conducted semi-structured interviews with 41 patients and surveyed 267 patients or family members to elicit their perspectives on satisfaction with traditional hospital communication methods, information needed to more fully engage in the patients' medical care, and potential solutions for improved hospital-based communication...
January 1, 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/29350223/what-is-career-success-for-academic-hospitalists-a-qualitative-analysis-of-early-career-faculty-perspectives
#7
Ethan Cumbler, Essey Yirdaw, Patrick Kneeland, Read Pierce, Patrick Rendon, Carrie Herzke, Christine D Jones
BACKGROUND: Understanding the concept of career success is critical for hospital medicine groups seeking to create sustainably rewarding faculty positions. Conceptual models of career success describe both extrinsic (compensation and advancement) and intrinsic (career satisfaction and job satisfaction) domains. How hospitalists define career success for themselves is not well understood. In this study, we qualitatively explore perspectives on how early-career clinician-educators define career success...
January 19, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29350060/-so-they-are-not-alive-dementia-reality-disjunctions-and-conversational-strategies
#8
Lars-Christer Hydén, Christina Samuelsson
In some conversations involving persons with Alzheimer's disease, the participants may have to deal with the difficulty that they do not share a common ground in terms of not only who is alive or dead, but even more, who could possibly be alive. It is as if the participants face a reality disjunction. There are very few empirical studies of this difficulty in conversations involving persons with Alzheimer's disease or other kinds of dementia diagnoses. Often studies of confabulation have a focus on the behavior and experience of the healthy participants, but rarely on the interaction and the collaborative contributions made by the person with dementia...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29348075/benzalkonium-chloride-benzethonium-chloride-and-chloroxylenol-three-replacement-antimicrobials-are-more-toxic-than-triclosan-and-triclocarban-in-two-model-organisms
#9
Virinchipuram S Sreevidya, Kade A Lenz, Kurt R Svoboda, Hongbo Ma
With the recent ban of triclosan (TCS) and triclocarban (TCC) from some personal care products, many replacement antimicrobial compounds have been used. Yet the potential health risk and environmental impact of these replacement compounds are largely unknown. Here we investigated the toxicological effects of three commonly used replacement antimicrobials, benzalkonium chloride (BAC), benzethonium chloride (BEC), and chloroxylenol (CX) to two model organisms, the nematode C. elegans and zebrafish (Danio rerio), and compared them to the banned TCS and TCC...
January 15, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29347891/changing-character-a-narrative-review-of-personality-change-in-psychotherapies-for-personality-disorder
#10
John R Keefe, Robert J DeRubeis
OBJECTIVE: Personality disorder (PD) is a negative prognostic indicator for treatment, and absolute improvements in functioning among these patients are often modest. This may be because personality features that give rise to dysfunction in PD are not targeted optimally during most treatments. METHOD: Attachment, mentalization, core beliefs, and personality organization/defense use were identified as personality constructs that have been pursued in treatment studies and that are proposed to underlie PD...
January 19, 2018: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/29346703/pursuing-personal-passion-learner-centered-research-mentoring
#11
William R Phillips
New researchers often face difficulty finding and focusing research questions. I describe a new tool for research mentoring, the Pursuing Personal Passion (P3) interview, and a systematic approach to help learners organize their curiosity and develop researchable questions aligned with their personal and professional priorities. The learner-centered P3 research interview parallels the patient-centered clinical interview. This paper reviews experience with 27 research mentees over the years 2009 to 2016, using the P3 approach to identify their initial research topics, classify their underlying passions and track the evolution into their final research questions...
January 2018: Family Medicine
https://www.readbyqxmd.com/read/29346234/a-qualitative-study-of-multidisciplinary-providers-experiences-with-the-transfer-process-for-injured-children-and-ideas-for-improvement
#12
Marcie Gawel, Beth Emerson, John S Giuliano, Alana Rosenberg, Karl E Minges, Shelli Feder, Pina Violano, Patricia Morrell, Judy Petersen, Emily Christison-Lagay, Marc Auerbach
OBJECTIVE: Most injured children initially present to a community hospital, and many will require transfer to a regional pediatric trauma center. The purpose of this study was 1) to explore multidisciplinary providers' experiences with the process of transferring injured children and 2) to describe proposed ideas for process improvement. METHODS: This qualitative study involved 26 semistructured interviews. Subjects were recruited from 6 community hospital emergency departments and the trauma and transport teams of a level I pediatric trauma center in New Haven, Conn...
January 16, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29346118/mycobacterium-avium-complex-pulmonary-disease-new-epidemiology-and-management-concepts
#13
Leah Lande, Jason George, Theodore Plush
PURPOSE OF REVIEW: The prevalence of Mycobacterium avium complex (MAC)-related pulmonary disease has been increasing because of environmental factors, changes in organism virulence, and evolving host susceptibility. Treatment is often complicated by adverse effects, development of drug resistance, and refractory disease, with recurrence rates as high as 25-45%. RECENT FINDINGS: Aerosolization of water, soil, or dusts are the likely sources of MAC-related pulmonary disease in susceptible individuals...
January 15, 2018: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29345750/mobility-trajectories-at-the-end-of-life-comparing-clinical-condition-and-latent-class-approaches
#14
June R Lunney, Steven M Albert, Robert Boudreau, Diane Ives, Suzanne Satterfield, Anne B Newman, Tamara Harris
OBJECTIVES: To assess mobility disability trajectories before death in a large sample of very old adults using two analytical approaches to determine how well they corresponded. DESIGN: Decedent sample from the Health, Aging and Body Composition (Health ABC) Study. Data were collected between 1997 and 2015. SETTING: Pittsburgh, Pennsylvania, and Memphis, Tennessee. PARTICIPANTS: Individuals randomly selected from well-functioning white Medicare beneficiaries and all black community residents meeting age criteria (70-79) (N = 3,075)...
January 18, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29342267/safety-of-single-dose-primaquine-in-g6pd-deficient-and-g6pd-normal-males-in-mali-without-malaria-an-open-label-phase-1-dose-adjustment-trial
#15
Ingrid Chen, Halimatou Diawara, Almahamoudou Mahamar, Koualy Sanogo, Sekouba Keita, Daouda Kone, Kalifa Diarra, Moussa Djimde, Mohamed Keita, Joelle Brown, Michelle E Roh, Jimee Hwang, Helmi Pett, Maxwell Murphy, Mikko Niemi, Bryan Greenhouse, Teun Bousema, Roly Gosling, Alassane Dicko
Background: The World Health Organization recommendation on the use of single low-dose primaquine (SLD-PQ) to reduce Plasmodium falciparum malaria transmission requires more safety data. Methods: We conducted an open-label, non-randomized, dose-adjustment trial of the safety of three single doses of primaquine in glucose-6-phosphate dehydrogenase (G6PD)-deficient adult males in Mali, followed by an assessment of safety in G6PD-deficient boys ages 11-17 years, and 5-10 years, including G6PD-normal control groups...
January 12, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29342172/driving-factors-of-retention-in-care-among-hiv-positive-msm-and-transwomen-in-indonesia-a-cross-sectional-study
#16
Adi Nugroho, Vicki Erasmus, Robert W S Coulter, Sushil Koirala, Oranuch Nampaisan, Wirastra Pamungkas, Jan Hendrik Richardus
Little is known about the prevalence of and factors that influence retention in HIV-related care among Indonesian men who have sex with men (MSM) and transgender women (transwomen, or waria in Indonesian term). Therefore, we explored the driving factors of retention in care among HIV-positive MSM and waria in Indonesia. This cross-sectional study involved 298 self-reported HIV-positive MSM (n = 165) and waria (n = 133). Participants were recruited using targeted sampling and interviewed using a structured questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29341859/an-indoor-air-quality-evaluation-in-a-residential-retrofit-project-using-spray-polyurethane-foam
#17
Shen Tian, Scott Ecoff, John Sebroski, Jason Miller, Harold Rickenbacker, Melissa Bilec
Understanding of indoor air quality (IAQ) during and after spray polyurethane foam (SPF) application is essential to protect the health of both workers and building occupants. Previous efforts such as field monitoring, micro-chamber/spray booth emission studies and fate/transport modeling have been conducted to understand the chemical exposure of SPF and guide risk mitigation strategies. However, each type of research has its limitation and can only reveal partial information on the relationship between SPF and IAQ...
January 17, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29341289/medically-unexplained-dermatologic-symptoms-muds-hiding-in-plain-sight
#18
David J Elpern
Illness is not the same as disease. Illness refers to "the innately human experience of symptoms and suffering." 1 Disease "is what the practitioner creates in recasting illness in terms of theories of disorder." 1 A person's subjective experience of how she feels may not assume an underlying pathology. Illness can be organic, psychological or spiritual. A person can feel ill, but not have a disease. This article is protected by copyright. All rights reserved.
January 17, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29340619/recurrent-serious-infections-in-patients-with-rheumatoid-arthritis-results-from-the-british-society-for-rheumatology-biologics-register
#19
Sujith Subesinghe, Andrew Ian Rutherford, Rachel Byng-Maddick, Kimme Leanne Hyrich, James Benjamin Galloway
Objectives: To establish the rate of recurrent infection in RA patients recruited to the British Society for Rheumatology Biologics Register - Rheumatoid Arthritis. Secondary objectives were to establish whether the organ class of index infection predicted future serious infection (SI). Methods: Using data from the British Society for Rheumatology Biologics Register - Rheumatoid Arthritis, a prospective observational cohort, we identified patients with at least one episode of SI...
January 10, 2018: Rheumatology
https://www.readbyqxmd.com/read/29340148/reducing-unnecessary-culturing-a-systems-approach-to-evaluating-urine-culture-ordering-and-collection-practices-among-nurses-in-two-acute-care-settings
#20
Robert Redwood, Mary Jo Knobloch, Daniela C Pellegrini, Matthew J Ziegler, Michael Pulia, Nasia Safdar
Background: Inappropriate ordering and acquisition of urine cultures leads to unnecessary treatment of asymptomatic bacteriuria (ASB). Treatment of ASB contributes to antimicrobial resistance particularly among hospital-acquired organisms. Our objective was to investigate urine culture ordering and collection practices among nurses to identify key system-level and human factor barriers and facilitators that affect optimal ordering and collection practices. Methods: We conducted two focus groups, one with ED nurses and the other with ICU nurses...
2018: Antimicrobial Resistance and Infection Control
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