keyword
MENU ▼
Read by QxMD icon Read
search

Zoster vaccine

keyword
https://www.readbyqxmd.com/read/29316913/influence-of-demographic-changes-on-the-impact-of-vaccination-against-varicella-and-herpes-zoster-in-germany-a-mathematical-modelling-study
#1
Johannes Horn, Oliver Damm, Wolfgang Greiner, Hartmut Hengel, Mirjam E Kretzschmar, Anette Siedler, Bernhard Ultsch, Felix Weidemann, Ole Wichmann, André Karch, Rafael T Mikolajczyk
BACKGROUND: Epidemiological studies suggest that reduced exposure to varicella might lead to an increased risk for herpes zoster (HZ). Reduction of exposure to varicella is a consequence of varicella vaccination but also of demographic changes. We analyzed how the combination of vaccination programs and demographic dynamics will affect the epidemiology of varicella and HZ in Germany over the next 50 years. METHODS: We used a deterministic dynamic compartmental model to assess the impact of different varicella and HZ vaccination strategies on varicella and HZ epidemiology in three demographic scenarios, namely the projected population for Germany, the projected population additionally accounting for increased immigration as observed in 2015/2016, and a stationary population...
January 9, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29310348/healthcare-utilization-and-costs-among-patients-with-herpes-zoster-and-solid-tumor-malignancy-on-chemotherapy-a-retrospective-cohort-study
#2
Jianbin Mao, Jeffrey T McPheeters, Lyn Finelli
Immunosuppressed patients with solid tumor malignancies (STMs) are particularly vulnerable to herpes zoster (HZ). This study estimated the incidence of HZ and evaluated healthcare resource utilization and costs for persons with STM receiving chemotherapy with and without incident HZ.We conducted a retrospective claims study of adults with STM receiving chemotherapy between January 1, 2010 and June 30, 2014. Patients were followed from their first chemotherapy date through development of HZ, health plan disenrollment, the study end date, or 24 months...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29309905/overall-and-comparative-risk-of-herpes-zoster-with-pharmacotherapy-for-inflammatory-bowel-diseases-a-nationwide-cohort-study
#3
Nabeel Khan, Dhruvan Patel, Chinmay Trivedi, Yash Shah, Gary Lichtenstein, James Lewis, Yu-Xiao Yang
BACKGROUND & AIMS: Patients with inflammatory bowel disease (IBD) might be at increased risk for herpes zoster infection. We sought to quantify the risk of herpes zoster in patients with IBD and evaluate the effects of IBD and IBD medications on the risk of herpes zoster. METHODS: We conducted 2 retrospective studies of populations of Veterans, from January 2000 through June 2016. In study 1, we compared the incidence of herpes zoster among patients with IBD receiving 5-ASA alone vs matched patients without IBD...
January 5, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29309521/long-term-effectiveness-of-the-live-zoster-vaccine-in-preventing-shingles-a-cohort-study
#4
Roger Baxter, Joan Bartlett, Bruce Fireman, Morgan Marks, John Hansen, Edwin Lewis, Laurie Aukes, Yong Chen, Nicola P Klein, Patricia Saddier
A live attenuated zoster vaccine was licensed in the United States in 2006 for prevention of shingles in persons aged 60 years or older; the indication was extended in 2011 to cover those aged 50-59 years. We assessed vaccine effectiveness (VE) against shingles for 8 years after immunization at Kaiser Permanente Northern California. VE was estimated by Cox regression with a calendar timeline that was stratified by birth year. We adjusted for demographics and time-varying covariates, including comorbidities and immune compromise...
January 1, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29307566/post-varicella-arterial-ischemic-stroke-in-denmark-2010-to-2016
#5
Ida Glode Helmuth, Kåre Mølbak, Peter Vilhelm Uldall, Anja Poulsen
BACKGROUND: Varicella, most often a benign disease of childhood, is associated with an increased risk of arterial ischemic stroke in children. The aim of the present study was to estimate the incidence of post-varicella arterial ischemic stroke in the Danish child population and describe clinical characteristics of children admitted with post-varicella arterial ischemic stroke. METHODS: In the Danish National Patient Register, we identified inpatients 28 days to 16 years of age with a discharge diagnosis of stroke or cerebrovascular disease from 2010 to 2016...
December 1, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29302565/candidate-for-a-live-vaccine
#6
Justin Ralph Abbatemarco, Alan Taege
Immune dysfunction is a well-known phenomenon in end-stage liver disease (ESLD). The pretransplant period offers a unique window for primary care physicians to optimize the transplant's vaccine protection before antirejection medications are initiated. Live vaccinations are selected cautiously but the varicella-zoster virus (VZV) vaccine, Zostavax, is recommended for pretransplant candidates. This case highlights an ESLD patient who developed disseminated cutaneous VZV within 30 days of vaccination.
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29297049/cost-effectiveness-of-the-adjuvanted-herpes-zoster-subunit-vaccine-in-older-adults
#7
Phuc Le, Michael B Rothberg
Importance: The live attenuated herpes zoster vaccine (ZVL) is recommended for immunocompetent adults 60 years or older, but the efficacy wanes with age and over time. A new adjuvanted herpes zoster subunit vaccine (HZ/su) has higher efficacy but might be more expensive. The choice of vaccines depends on their relative values. Objective: To assess the cost-effectiveness of HZ/su. Design, Setting, and Participants: Markov decision model with transition probabilities based on the US medical literature...
January 2, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29297047/evolution-of-herpes-zoster-vaccines-and-their-economic-value
#8
Mehdi Najafzadeh
No abstract text is available yet for this article.
January 2, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29285399/fighting-against-a-protean-enemy-immunosenescence-vaccines-and-healthy-aging
#9
Giuseppe Del Giudice, Jörg J Goronzy, Beatrix Grubeck-Loebenstein, Paul-Henri Lambert, Tomas Mrkvan, Jeffrey J Stoddard, T Mark Doherty
The progressive increase of the aged population worldwide mandates new strategies to ensure sustained health and well-being with age. The development of better and/or new vaccines against pathogens that affect older adults is one pivotal intervention in approaching this goal. However, the functional decline of various physiological systems, including the immune system, requires novel approaches to counteract immunosenescence. Although important progress has been made in understanding the mechanisms underlying the age-related decline of the immune response to infections and vaccinations, knowledge gaps remain, both in the areas of basic and translational research...
2018: NPJ Aging and Mechanisms of Disease
https://www.readbyqxmd.com/read/29276161/impact-of-vaccination-history-on-serological-testing-in-pregnant-women
#10
Michaël Desjardins, Isabelle Boucoiran, Caroline Paquet, Céline Laferrière, Anne Gosselin-Brisson, Annie-Claude Labbé, Valérie Martel-Laferrière
OBJECTIVE: Serological testing guidelines for vaccine-preventable infectious diseases in pregnant women are heterogeneous. It is unclear how vaccination history influences health care workers' (HCWs) attitudes about testing. The aim of this study was to describe current practices in screening for rubella, hepatitis B, and varicella-zoster virus (VZV) in pregnant women in the province of Québec. METHODS: In 2015, an electronic survey was distributed to HCWs who followed the case of at least one pregnant woman in the previous year and who could be contacted by email by their professional association...
December 21, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29276017/evaluation-of-the-effect-of-the-herpes-zoster-vaccination-programme-3-years-after-its-introduction-in-england-a-population-based-study
#11
Gayatri Amirthalingam, Nick Andrews, Philip Keel, David Mullett, Ana Correa, Simon de Lusignan, Mary Ramsay
BACKGROUND: In 2013, a herpes zoster vaccination programme was introduced in England for adults aged 70 years with a phased catch-up programme for those aged 71-79 years. We aimed to evaluate the effect of the first 3 years of the vaccination programme on incidence of herpes zoster and postherpetic neuralgia in this population. METHODS: In this population-based study, we extracted data from the Royal College of General Practitioners sentinel primary care network on consultations with patients aged 60-89 years for herpes zoster and postherpetic neuralgia occurring between Oct 1, 2005, and Sept 30, 2016, obtaining data from 164 practices...
December 21, 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/29276016/uk-experience-of-herpes-zoster-vaccination-can-inform-varicella-zoster-virus-policies
#12
Benson Ogunjimi, Philippe Beutels
No abstract text is available yet for this article.
December 21, 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/29273977/negative-igg-varicella-zoster-virus-antibody-status-immune-responses-pre-and-post-re-immunization
#13
Tamar A Smith-Norowitz, Tehila A Saadia, Kevin B Norowitz, Rauno Joks, Helen G Durkin, Stephan Kohlhoff
INTRODUCTION: Varicella zoster virus (VZV) causes chicken pox and herpes zoster and is a self-limiting disease in healthy children. Vaccination is recommended for children, adolescents, and adults. This study discusses a healthy pediatric patient with negative immunoglobulin (Ig) G VZV antibody (Ab) status after two doses of varicella vaccine and then subsequently re-immunized. Since measurement of serum IgG titers alone may not reflect vaccine protection, we further evaluated cell-mediated and humoral immune responses before and after re-immunization...
December 22, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29242077/vaccine-type-mutations-identified-in-varicella-zoster-virus-passaged-in-cell-culture
#14
Seok Cheon Kim, Youn Hee Won, Ji Seon Park, Jeong Seon Jeon, Jin Hyun Ahn, Moon Jung Song, Ok Sarah Shin, Chan Hee Lee
Varicella-zoster virus (VZV) is a causative agent for chickenpox and shingles. Comparative genomic sequence analysis of clinical and vaccine strains suggested potential sites responsible for attenuation. In this study, low and high passages of two VZV clinical strains cultured in human fibroblast cells were compared for genomic DNA sequences and growth characteristics. Mutations were detected at 187 and 162 sites in the strain YC01 and YC02, respectively. More than 86% of mutations were found in open reading frames, and ORF62 exhibited highest frequency of mutations...
December 11, 2017: Virus Research
https://www.readbyqxmd.com/read/29232664/vaccination-practices-in-pediatric-dialysis-patients-across-europe-a-european-pediatric-dialysis-working-group-and-european-society-for-pediatric-nephrology-dialysis-working-group-study
#15
Sevcan A Bakkaloğlu, Yesim Özdemir Atikel, Fabio Paglialonga, Constantinos J Stefanidis, Varvara Askiti, Enrico Vidal, Gema Ariceta, Engin Melek, Enrico Verrina, Nikoleta Printza, Karel Vondrak, Aleksandra Zurowska, Ilona Zagozdzon, Mesiha Ekim, Elif Nursel Özmert, Stephanie Dufek, Augustina Jankauskiene, Claus Peter Schmitt, Eszter Lévai, Johan Vande Walle, Nur Canpolat, Tuula Holtta, Michel Fischbach, Guenter Klaus, Christoph Aufricht, Rukshana Shroff, Alberto Edefonti
BACKGROUND: Data on the immunization practices in pediatric chronic kidney disease (CKD) patients are scarce. The purpose of this study was to evaluate current vaccination practices for children on dialysis across European pediatric nephrology centers. METHODS: A total of 18 tertiary pediatric nephrology centers from 12 European countries were included in the study. The data on universal national immunization programs and immunization practices for children with chronic disease or risk were recorded from European Center for Disease Prevention and Control and the World Health Organization...
December 12, 2017: Nephron
https://www.readbyqxmd.com/read/29232420/atypical-herpes-zoster-presentation-in-a-healthy-vaccinated-pediatric-patient
#16
Alicia T Dagrosa, Lindsey K Collins, M Shane Chapman
We report the case of a 6-year-old girl with no notable medical history who presented to the dermatology clinic for evaluation of left leg pain with an overlying erythematous rash of 4 days' duration. Clinical examination revealed pink patches and plaques in a unilateral L5 distribution with an isolated pinpoint vesicle. Direct fluorescent antibody testing confirmed varicella-zoster virus (VZV) infection, establishing a diagnosis of herpes zoster (HZ). The patient previously had received the VZV vaccine in the left leg and arm and had no history of primary VZV infection...
November 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29231748/relationship-between-patient-copayments-in-medicare-part-d-and-vaccination-claim-status-for-herpes-zoster-and-tetanus-diphtheria-acellular-pertussis
#17
Songkai Yan, Maral DerSarkissian, Rachel H Bhak, Patrick Lefebvre, Mei Sheng Duh, Girishanthy Krishnarajah
OBJECTIVE: To assess the relationship between copay amount and vaccination claim submission status for tetanus-diphtheria-acellular pertussis (Tdap) and herpes zoster (GSK study identifier: HO-14-14319). METHODS: Retrospective analyses were performed using vaccination administrative claims data in patients aged ≥65 years with ≥1 claim for Tdap or zoster vaccines between 2012-2014. To avoid confounding by other financial responsibility, analyses were conducted among patients in the copayment phase of insurance...
December 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29230484/-vaccination-in-advanced-age
#18
REVIEW
H J Heppner, A Leischker, P Wutzler, A Kwetkat
Infectious diseases are responsible for up to 5% of fatalities even in developed countries. In addition, there is an increasing susceptibility for infections in elderly people due to physiological aging of the immune system. The principles of vaccination are based on a targeted activation of the human immune system. Principally, a distinction is made between passive immunization, i.e. the application of specific antibodies against a pathogen and active immunization. In active immunization, i.e. vaccination, weakened (attenuated) or dead pathogens or components of pathogens (antigens) are administered...
December 11, 2017: Der Internist
https://www.readbyqxmd.com/read/29224964/one-or-two-doses-of-live-varicella-virus-containing-vaccines-efficacy-persistence-of-immune-responses-and-safety-six-years-after-administration-in-healthy-children-during-their-second-year-of-life
#19
Ouzama Henry, Jerzy Brzostek, Hanna Czajka, Giedra Leviniene, Olga Reshetko, Roberto Gasparini, Petr Pazdiora, Doina Plesca, Maria Giuseppina Desole, Rimantas Kevalas, Giovanni Gabutti, Michael Povey, Bruce Innis
BACKGROUND: This phase III B follow-up of an initial multicenter study (NCT00226499) will evaluate the ten-year efficacy of two doses of the combined measles-mumps-rubella-varicella vaccine (MMRV) and one dose of the live attenuated varicella vaccine (V) versus a measles-mumps-rubella control group (MMR) for the prevention of clinical varicella disease. Here we present efficacy results for six years post-vaccination. METHODS: In phase A of the study, healthy children aged 12-22 months from ten European countries were randomized (3:3:1) and received either two doses of MMRV, or one dose of combined MMR and one dose of monovalent varicella vaccine (MMR+V), or two doses of the MMR vaccine (control), 42 days apart...
December 7, 2017: Vaccine
https://www.readbyqxmd.com/read/29216315/the-pul37-tegument-protein-guides-alpha-herpesvirus-retrograde-axonal-transport-to-promote-neuroinvasion
#20
Alexsia L Richards, Patricia J Sollars, Jared D Pitts, Austin M Stults, Ekaterina E Heldwein, Gary E Pickard, Gregory A Smith
A hallmark property of the neurotropic alpha-herpesvirinae is the dissemination of infection to sensory and autonomic ganglia of the peripheral nervous system following an initial exposure at mucosal surfaces. The peripheral ganglia serve as the latent virus reservoir and the source of recurrent infections such as cold sores (herpes simplex virus type I) and shingles (varicella zoster virus). However, the means by which these viruses routinely invade the nervous system is not fully understood. We report that an internal virion component, the pUL37 tegument protein, has a surface region that is an essential neuroinvasion effector...
December 7, 2017: PLoS Pathogens
keyword
keyword
32230
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"