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https://www.readbyqxmd.com/read/29753630/comparison-of-two-training-methods-in-community-pharmacy-project-vaccinate
#1
James L Lin, Jennifer L Bacci, Marci J Reynolds, Yushi Li, Rachel G Firebaugh, Peggy S Odegard
OBJECTIVE: To compare the impact of a whole-staff training strategy to a train-the-trainer strategy on 1) the number of influenza, pneumococcal, herpes zoster, and pertussis vaccines administered by community pharmacists to adults; 2) staff confidence; and 3) fidelity to the intervention. SETTING: Eight Quality Food Centers (QFC) Pharmacies in Seattle, Washington. PRACTICE DESCRIPTION: QFC Pharmacy is a grocery store division of The Kroger Co...
May 9, 2018: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29743372/-breadth-and-functionality-of-varicella-zoster-virus-glycoprotein-specific-antibodies-identified-after-zostavax-vaccination-in-humans
#2
Nicole L Sullivan, Morgan A Reuter-Monslow, Janet Sei, Eberhard Durr, Carl W Davis, Cathy Chang, Megan McCausland, Andreas Wieland, David Krah, Nadine Rouphael, Aneesh K Mehta, Mark J Mulligan, Bali Pulendran, Rafi Ahmed, Kalpit A Vora
Herpes zoster (HZ/shingles) is the clinical manifestation of varicella zoster virus (VZV) reactivation. HZ typically develops as people age due to decreased cell-mediated immunity. However, the importance of antibodies for immunity against HZ prevention remains to be understood. The goal of this study was to examine the breadth and functionality of VZV-specific antibodies after vaccination with a live attenuated HZ vaccine (Zostavax). Direct enumeration of VZV-specific antibody secreting cells (ASC) via ELISPOT showed that Zostavax can induce both IgG and IgA ASCs seven days after vaccination, but not IgM ASCs...
May 9, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29742472/impact-of-postherpetic-neuralgia-a-six-year-population-based-analysis-on-people-aged-50-years-or-older-%C3%A2-%C3%A2-%C3%A2
#3
Cintia Muñoz-Quiles, Mónica López-Lacort, Alejandro Orrico-Sánchez, Javier Díez-Domingo
OBJECTIVES: To estimate the incidence and burden of postherpetic neuralgia (PHN) and to investigate risk factors for PHN in the Valencia Region of Spain. METHODS: Data were extracted from population and healthcare databases from the Valencia Region (2009-2014). Herpes zoster (HZ) and PHN were defined using ICD-9 codes and drug prescriptions in people aged ≥ 50 years. The risk of HZ patients for developing PHN and potential risk factors (diabetes mellitus, COPD and heart failure) were investigated...
May 6, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29742283/vaccination-practices-in-dialysis-patients-a-narrative-review
#4
REVIEW
Georges Kosmadakis, Julie Albaret, Enrique Da Costa Correia, Frederic Somda, Didier Aguilera
In a period of turmoil concerning vaccination practices, there is a serious conflict between scientifically reasonable, evidence-based guidelines and the far-fetched rumors or misconceptions concerning the vaccination practices in the general population. When a significant portion of the medical and paramedical personnel may be deliberately unvaccinated against common biological agents, achieving effective vaccination rates in the dialysis population may be complicated. Vaccination rates are unacceptably low in dialysis patients and seroconversion rates are even lower; further, serological follow-up is generally poor...
May 9, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29741721/update-from-the-advisory-committee-on-immunization-practices
#5
Sean T O'Leary, David W Kimberlin, Yvonne A Maldonado
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, each of whom is appointed to a 4-year term. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. The ACIP met on October 25 and 26, 2017, to discuss herpes zoster vaccine, the child/adolescent and adult vaccination schedules, Japanese encephalitis (JE) epidemiology and vaccines, pneumococcal vaccines, anthrax vaccines and disaster preparedness, hepatitis A outbreaks, influenza surveillance and vaccination coverage, vaccine safety, and considerations for a potential third dose of measles-mumps-rubella (MMR) vaccine to combat ongoing mumps outbreaks...
May 7, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29731177/administrative-data-to-explore-the-role-of-family-history-as-a-risk-factor-for-herpes-zoster
#6
Rafael Harpaz, Rebecca M Dahl
We used administrative data to study the impact of family history on the risk of herpes zoster (HZ). Our HZ cases and our HZ family history were both ascertained on the basis of medically attended diagnoses, without reliance on self-report or recall bias. Family history was associated with HZ risk among both siblings and parents. The strength of the association differed when the index child was latently infected with vaccine-strain vs wild-type varicella zoster virus.
May 3, 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29730833/assessing-and-improving-zoster-vaccine-uptake-in-a-homeless-population
#7
Laura Kaplan-Weisman, Eve Waltermaurer, Casey Crump
The herpes zoster (shingles) vaccine is recommended for all adults aged ≥ 60 years without contraindications to prevent shingles and post-herpetic neuralgia. There are no published studies on zoster vaccination rates, barriers, or workflows in adults who have experienced homelessness. Due to barriers specific to this vaccine, including difficulty determining insurance coverage, high upfront costs, need for storage in a freezer, and under-prescription by physicians, uptake is lower compared to other recommended vaccines for older adults...
May 5, 2018: Journal of Community Health
https://www.readbyqxmd.com/read/29721782/herpes-zoster-in-frail-elderly-patients-prevalence-impact-management-and-preventive-strategies
#8
REVIEW
Ermanno Zorzoli, Francesca Pica, Giulia Masetti, Elisabetta Franco, Antonio Volpi, Giovanni Gabutti
Population aging is a worldwide phenomenon with significant and manifold impacts on society. Advanced age correlates with the onset of frailty. In this vulnerable state, the immune response is weakened and a higher susceptibility to infectious diseases is observed. The present narrative review aims to cover the topic of herpes zoster (HZ) and its complications in frail populations. The lifetime risk of developing HZ is estimated at about 20-30%, and the risk increases with age. In older people, HZ can lead to the inability to recover the lifestyle, the interests, and the level of activity that existed before its development...
May 2, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29720364/monitoring-interest-in-herpes-zoster-vaccination-analysis-of-google-search-data
#9
Elyse J Berlinberg, Michael S Deiner, Travis C Porco, Nisha R Acharya
BACKGROUND: A new recombinant subunit vaccine for herpes zoster (HZ or shingles) was approved by the United States Food and Drug Administration on October 20, 2017 and is expected to replace the previous live attenuated vaccine. There have been low coverage rates with the live attenuated vaccine (Zostavax), ranging from 12-32% of eligible patients receiving the HZ vaccine. OBJECTIVE: This study aimed to provide insight into trends and potential reasons for interest in HZ vaccination...
May 2, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29720076/paediatric-active-enhanced-disease-surveillance-paeds-annual-report-2015-prospective-hospital-based-surveillance-for-serious-paediatric-conditions
#10
Jocelynne E McRae, Helen E Quinn, Kristine Macartney
Introduction: The Paediatric Active Enhanced Disease Surveillance (PAEDS) network is a hospital-based active surveillance system employing prospective case ascertainment for selected serious childhood conditions, particularly vaccine preventable diseases and potential adverse events following immunisation (AEFI). PAEDS data is used to better understand these conditions, inform policy and practice under the National Immunisation Program, and enable rapid public health responses for certain conditions of public health importance...
September 1, 2017: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/29708930/management-of-chronic-complications-associated-with-herpes-zoster-ophthalmicus
#11
Saujanya Vadoothker, Bennie H Jeng
PURPOSE OF REVIEW: Herpes zoster ophthalmicus (HZO) has the potential to cause significant visual morbidity and functional disability in patients with recalcitrant disease, keratitis, and postherpetic neuralgia. This article will review the current methods of prevention and treatment of anterior segment-related chronic complications of HZO. RECENT FINDINGS: HZO-related anterior segment ocular complications can range to include conjunctivitis, keratitis, and uveitis that can all be difficult to manage...
April 27, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29706010/long-term-study-showed-that-vaccination-protected-paediatric-renal-transplant-recipients-from-life-threatening-varicella-zoster-virus
#12
Jenny K Lindahl, Vanda Friman, Susanne Westphal Ladfors, Sverker Hansson, Rune Andersson, Marianne Jertborn, Susanne Woxenius
AIM: Renal transplant patients are particularly susceptible to highly contagious diseases due to their reduced immunity. We studied transplant recipients to gauge their varicella zoster virus (VZV) serology status over time and the outcome of any VZV infections. METHOD: This retrospective study comprised 85 children who underwent renal transplants in Gothenburg, Sweden, from1986-2014, at a mean age of eight (1-18) years. The children's medical records were reviewed and 47 had the VZV infection pre-transplant and 38 had been vaccinated pre-transplant...
April 29, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29702494/current-vaccines-for-the-prevention-of-herpes-zoster
#13
Allister Gibbons, Anat Galor
PURPOSE OF REVIEW: To summarize the recent advances in the prevention of herpes zoster. The recent Food and Drug Administration (FDA) approval of an adjuvanted subunit vaccine may have a significant impact on the prevention of herpes zoster ophthalmicus. RECENT FINDINGS: There are currently two commercially available vaccines for the prevention of herpes zoster: a live-attenuated vaccine and a new recombinant subunit vaccine. The latter has been shown to be more effective, have fewer contraindications, but requires two separate inoculations, has higher reactogenicity, and has only short-term postmarketing surveillance...
April 26, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29680914/the-potential-public-health-impact-of-herpes-zoster-vaccination-of-people-aged-%C3%A2-50-years-in-japan-results-of-a-markov-model-analysis
#14
Daisuke Watanabe, Akiko Mizukami, Katsiaryna Holl, Desmond Curran, Desirée Van Oorschot, Lijoy Varghese, Makoto Shiragami
INTRODUCTION: The aim of this study was to compare the public health impact of introducing two herpes zoster (HZ) vaccines into the vaccination programs for the Japanese population aged ≥ 50 years: a single-dose Varicella Vaccine Live (VVL) or a two-dose adjuvanted Recombinant Zoster Vaccine (RZV). METHODS: A multi-cohort static Markov model was developed to follow age cohorts (50-59, 60-69, 70-79 and ≥ 80 years) over their remaining lifetime. Japan-specific data inputs for the model were obtained from Japanese data sources...
April 21, 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29677646/adjuvant-strategies-to-improve-vaccination-of-the-elderly-population
#15
REVIEW
Birgit Weinberger
Immunosenescence contributes to increased incidence and severity of many infections in old age and is responsible for impaired immunogenicity and efficacy of vaccines. Adjuvants are one strategy to enhance immunogenicity of vaccines. The oil-in-water emulsions MF59TM and AS03, as well as a virosomal vaccine have been licensed in seasonal or pandemic influenza vaccines and are/were used successfully in the elderly. AS01, a liposome-based adjuvant comprising two immunostimulants has recently been approved in a recombinant protein vaccine for older adults, which showed very high efficacy against herpes zoster in clinical trials...
April 17, 2018: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29661022/low-rates-of-vaccination-for-herpes-zoster-in-older-people-living-with-hiv
#16
Kristine M Erlandson, Amber Streifel, Alexander Novin, Kellie Hawkins, Clayton Foster, Jacob Langness, Mary Bessesen, Julian Falutz, Abeer Moanna, David Looney, Scott Johns, Joseph Nguyen, Michael Oxman, Myron Levin
BACKGROUND: Herpes zoster (HZ) occurs at a higher age-specific rate in people living with HIV (PLWH) than in the general population. We implemented a quality improvement study to assess herpes zoster vaccine (HZV) usage among PLWH, assess HZV usage after additional reminders/prompts, and identify barriers to HZV among older PLWH. METHODS: HZV rates in PLWH were determined in six institutions with varying payment structures. For the intervention, Part 1, PLWH eligible for HZV at the University of Colorado were identified, and providers were notified of patient eligibility...
April 17, 2018: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/29659663/real-world-evidence-for-regulatory-decisions-concomitant-administration-of-zoster-vaccine-live-and-pneumococcal-polysaccharide-vaccine
#17
Katia Bruxvoort, Lina S Sy, Yi Luo, Hung Fu Tseng
The US Food and Drug Administration is charged with expanding the use of real world evidence (RWE) for regulatory decisions. As a test case for RWE to support regulatory decisions, we present the scenario of concomitant vaccination with zoster vaccine live (ZVL) and 23-valent pneumococcal polysaccharide vaccine (PPSV23). The prescribing information states that these vaccines should not be given concurrently, based on a small trial using varicella zoster virus antibody levels as a correlate of ZVL efficacy, even though ZVL protects against herpes zoster via cell-mediated immunity...
April 11, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29653205/varicella-zoster-virus-reactivation-in-adult-survivors-of-hematopoietic-cell-transplantation-how-do-we-best-protect-our-patients
#18
REVIEW
Catherine J Lee, Bipin N Savani, Per Ljungman
Reactivation of varicella zoster virus (VZV) remains a significant public health burden for long-term survivors of hematopoietic cell transplantation. Delayed immune reconstitution after transplantation due to immunosuppression, posttransplant therapies, poor engraftment, and graft-versus-host disease leave a large number of patients at risk for herpes zoster (shingles) and its highly morbid complications. Although prophylaxis with acyclovir or valacyclovir has reduced the incidence of VZV reactivation as long as prophylaxis is continued, the incidence of disease in the late posttransplant period or after stopping prophylaxis is greater in the HCT population than the general public...
April 10, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29650086/influenza-pneumococcal-hepatitis-b-and-herpes-zoster-vaccinations
#19
Nadira Husein, Ashen Chetty
No abstract text is available yet for this article.
April 2018: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29621623/maritime-varicella-illness-and-death-reporting-u-s-2010-2015
#20
Marion E Rice, Millicent Bannerman, Mona Marin, Adriana Lopez, Melissa M Lewis, Caroline Stamatakis, Joanna Regan
BACKGROUND: Ships destined for, or departing from, U.S. ports of entry must report certain signs and symptoms of potentially communicable diseases of public health interest among travelers to the Division of Global Migration and Quarantine (DGMQ) at the Centers for Disease Control and Prevention. METHODS: We reviewed ships' varicella case and outbreak reports from January 2010 through December 2015. RESULTS: DGMQ received 967 reports of varicella and 13 reports of herpes zoster...
April 2, 2018: Travel Medicine and Infectious Disease
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