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https://www.readbyqxmd.com/read/28073522/antisynthetase-syndrome-analysis-of-11-cases
#1
Ester Zamarrón-de Lucas, Luis Gómez Carrera, Gema Bonilla, Dessiree Petit, Alberto Mangas, Rodolfo Álvarez-Sala
INTRODUCTION: Antisynthetase syndrome (ASS) is characterised by a series of clinical manifestations such as myositis, fever, mechanic's hands and diffuse interstitial lung disease (ILD), all associated with positivity to antisynthetase antibodies. The presence of ILD will be that, to a great extent it will mark the response to treatment and prognosis. PATIENTS AND METHODS: Eleven cases of patients with ASS and pulmonary involvement in monitoring at a Pulmonary monographic consult in a third level hospital consult are described...
January 7, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28068946/ct-characteristics-of-non-small-cell-lung-cancer-with-epidermal-growth-factor-receptor-mutation-a-systematic-review-and-meta-analysis
#2
Zenghui Cheng, Fei Shan, Yuesong Yang, Yuxin Shi, Zhiyong Zhang
BACKGROUND: To systematically investigate the relationship between CT morphological features and the presence of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC). METHODS: All studies about the CT morphological features of NSCLC with EGFR mutations published between January 1, 2000 and March 15, 2015 were searched in the PubMed and EMBASE databases. Qualified studies were selected according to inclusion criteria. The frequency of EGFR mutations and CT features of ground-glass opacity (GGO) content, tumor size, cavitation, air-bronchogram, lobulation, and spiculation were extracted...
January 10, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28066679/image-guided-techniques-for-localizing-pulmonary-nodules-in-thoracoscopic-surgery
#3
REVIEW
Mong-Wei Lin, Jin-Shing Chen
Low-dose computed tomography (LDCT) screening has increased the detection rate for small pulmonary nodules with ground-glass opacity (GGO) in the peripheral lung parenchyma. Minimally invasive thoracoscopic surgery for these lung nodules is challenging for thoracic surgeons, and image-guided preoperative localization is mandatory for their successful resection. Image-guided localization methods primarily include two imaging tools: computed tomography (CT) and bronchoscopy. These different methods may use different localized materials, including hookwires, dyes, microcoils, fiducial markers, contrast media, and radiotracers...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28058100/non-mucinous-lepidic-predominant-adenocarcinoma-presenting-with-extensive-aerogenous-spread
#4
Yusuke Takanashi, Shogo Tajima, Masaru Tsukui, Kazuya Shinmura, Takamitsu Hayakawa, Tsuyoshi Takahashi, Hiroshi Neyatani, Kazuhito Funai
An extremely rare case of non-mucinous lepidic-predominant invasive adenocarcinoma (LPA) showing extensive aerogenous spread with a pneumonic presentation is reported. A 73-year-old woman was referred to our hospital because of an infiltrative shadow on chest xray. Chest computed tomography revealed extensive ground glass opacities in the right lower lobe, which was accompanied by infiltrative shadow with a pneumonic presentation. Invasive mucinous adenocarcinoma was presumed, and a partial resection of the right lower lobe was done...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/28050475/role-of-hrct-chest-in-post-stem-cell-transplant-recipients-suspected-of-pulmonary-complications
#5
Abhishek Dwivedi, R Ravi Kumar, Ajay Sharma, S K Pannu
INTRODUCTION: Stem cell transplantation is today's procedure of choice for management of various hematopoietic malignant and severe immunogenic disorders. High Resolution Computed Tomography (HRCT) is a common technique for the diagnosis of pulmonary complications in stem cell transplant recipients. There are a large number of complications which can complicate the post-transplant period. AIM: To study the role of HRCT chest in stem cell transplant patients developing pulmonary complications, detect any evidence of infection, detect clinical signs of lung infections, Graft versus Host Disease (GvHD) or other regimen related toxicities outlined earlier, detect any evidence of GvHD and correlate these clinical signs with radiological changes in the lungs...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050004/interstitial-lung-disease-induced-by-pazopanib-treatment
#6
Shotaro Ide, Noriho Sakamoto, Shintaro Hara, Atsuko Hara, Tomoyuki Kakugawa, Yoichi Nakamura, Yoji Futsuki, Koichi Izumikawa, Yuji Ishimatsu, Katsunori Yanagihara, Hiroshi Mukae
Although pneumothorax has been reported to be a major pulmonary adverse event in patients treated with pazopanib, a multikinase inhibitor, drug-induced interstitial lung disease (DILD) has not been reported. A 74-year-old Japanese man who received pazopanib for the treatment of femoral leiomyosarcoma and lung metastasis presented with dyspnea and fatigue. He had mild interstitial pneumonia when pazopanib treatment was initiated. Chest computed tomography revealed progressive bilateral ground-glass opacity (GGO) and traction bronchiectasis...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28049240/characteristics-of-adenovirus-pneumonia-in-korean-military-personnel-2012-2016
#7
Hee Yoon, Byung Woo Jhun, Hojoong Kim, Hongseok Yoo, Sung Bum Park
Adenovirus (AdV) can cause severe pneumonia in non-immunocompromised host, but limited data exist on the distinctive characteristics of AdV pneumonia in non-immunocompromised patients. We evaluated distinctive clinico-laboratory and radiological characteristics and outcomes of AdV pneumonia (n = 179), compared with non-AdV pneumonia (n = 188) in Korean military personnel between 2012 and 2016. AdV pneumonia patients had a higher rate of consolidation with ground-glass opacity (101/152) in lobar distribution (89/152) on computed tomography (CT) (P < 0...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28048515/th-ab-207a-09-tailoring-tcm-schemes-to-a-task-evaluating-the-impact-of-customized-tcm-profiles-on-detection-of-lung-nodules-in-simulated-ct-lung-cancer-screening
#8
J Hoffman, F Noo, S Young, M McNitt-Gray
PURPOSE: Recent work has shown that current TCM profile designs boost detection of low-contrast lung lesions in the lung apices, but yield reduced detection performance in the mid and lower lung regions relative to fixed tube current cases. This observed imbalance suggests that the TCM scheme might be tailored in new ways to maximize nodule detection throughout the entire lung. In this work, we begin a preliminary investigation into custom TCM profiles in an attempt to achieve uniform lesion detection throughout the extent of the lung...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046577/tu-h-campus-jep2-03-machine-learning-based-delineation-framework-of-gtv-regions-of-solid-and-ground-glass-opacity-lung-tumors-at-datasets-of-planning-ct-and-pet-ct-images
#9
K Ikushima, H Arimura, Z Jin, H Yabuuchi, J Kuwazuru, Y Shioyama, T Sasaki, H Honda, M Sasaki
PURPOSE: In radiation treatment planning, delineation of gross tumor volume (GTV) is very important, because the GTVs affect the accuracies of radiation therapy procedure. To assist radiation oncologists in the delineation of GTV regions while treatment planning for lung cancer, we have proposed a machine-learning-based delineation framework of GTV regions of solid and ground glass opacity (GGO) lung tumors following by optimum contour selection (OCS) method. METHODS: Our basic idea was to feed voxel-based image features around GTV contours determined by radiation oncologists into a machine learning classifier in the training step, after which the classifier produced the degree of GTV for each voxel in the testing step...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28035877/a-woman-with-asthma-and-ground-glass-opacities
#10
Inderjit Singh, Robert Kaner
No abstract text is available yet for this article.
January 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28031833/respiratory-bronchiolitis-associated-interstitial-lung-disease-with-obvious-paraseptal-emphysema
#11
Yun Zhou, Zhiyi He, Jing Bai, Xiaoning Zhong
Respiratory bronchiolitis-associated interstitial lung disease (RBILD) is a distinct clinical-pathological disease described almost exclusively among cigarette smokers. Normally, the most common manifestations in computed tomography findings of RBILD are central and peripheral bronchial wall thickening, centrilobular nodules, ground glass opacity, and mild centrilobular emphysema in the upper lobes. In this study, we report a current smoker presenting with diffuse ground glass opacity in the entire lungs along with paraseptal emphysema...
November 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28031830/development-of-diffuse-alveolar-damage-after-initiation-of-nijutsuto
#12
Motoyasu Kato, Shinichi Sasaki, Hiroshi Izumi, Toshimasa Uekusa, Shigeru Tominaga, Kazuhisa Takahashi
Chinese traditional medicine, Nijutsuto, is used to treat patients with frozen shoulder and osteoarthritis. Herbal medicine is often linked to the development of interstitial lung disease. An 83-year-old Japanese man with osteoarthritis who was on Nijutsuto was admitted to our hospital with dyspnoea and severe cough after 2 weeks from initiation of Nijutsuto. A chest computed tomography scan on admission showed diffuse ground glass opacity with traction bronchiectasis. Thus, he was diagnosed with Nijutsuto-induced interstitial lung disease, and was treated with a high dose of methylprednisolone and cyclophosphamide...
November 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28031829/summer-type-hypersensitivity-pneumonitis-in-a-patient-with-rheumatoid-arthritis-on-methotrexate-and-tacrolimus
#13
Hirotsugu Ohkubo, Minami Okayama, Kensuke Fukumitsu, Akio Niimi
A 59-year-old woman receiving methotrexate and tacrolimus for rheumatoid arthritis (RA) was referred to our hospital following bilateral ground-glass opacity observed in her chest X-ray and elevated serum KL-6. After methotrexate and tacrolimus cessation, shortness of breath developed and ground-glass opacity observed in the chest computed tomography rapidly worsened. Bronchoalveolar lavage showed increased lymphocytes, and trans-bronchial lung biopsy confirmed lymphocytic alveolitis. In addition, the patient had serum antibodies against Trichosporon asahii, a fungal pathogen...
November 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28029320/pulmonary-infiltrates-in-a-patient-with-advanced-melanoma
#14
Charles A Powell
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
December 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28003110/eosinophilic-pneumonia-caused-by-daptomycin-six-cases-from-two-institutions-and-a-review-of-the-literature
#15
Jun Hirai, Mao Hagihara, Shusaku Haranaga, Takeshi Kinjo, Hiroe Hashioka, Hideo Kato, Daisuke Sakanashi, Yuka Yamagishi, Hiroshige Mikamo, Jiro Fujita
Here we report six cases of daptomycin (DAP)-induced eosinophilic pneumonia (DIEP) encountered at two medical centers and present a review of 43 DIEP patients from 26 studies to compare the clinical characteristics and radiographic findings of acute and chronic eosinophilic pneumonia (AEP; CEP). Four of the six patients did not exhibit respiratory symptoms, and one patient with only fever was misdiagnosed with DAP-induced fever. According to our literature review and the present findings, male sex and old age were dominant risk factors for DIEP...
December 18, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/27995057/rapidly-progressive-interstitial-lung-disease-due-to-anti-mda-5-antibody-positive-clinically-amyopathic-dermatomyositis-complicated-with-cervical-cancer-successful-treatment-with-direct-hemoperfusion-using-polymyxin-b-immobilized-fiber-column-therapy
#16
Hidenori Ichiyasu, Yasumiko Sakamoto, Chieko Yoshida, Kazuhiko Sakamoto, Ryosuke Fujita, Go Nakayama, Hiroko Okabayashi, Sho Saeki, Shinichiro Okamoto, Hirotsugu Kohrogi
The anti-melanoma differentiation-associated gene 5 (MDA-5) antibody is a marker of clinically amyopathic dermatomyositis (CADM) and rapidly progressive interstitial lung disease (ILD) with acute respiratory failure. A 35-year-old woman with cervical cancer showed Gottron's papules, severe hypoxemia, and diffuse ground-glass opacities on chest computed tomography. She was diagnosed with rapidly progressive ILD associated with CADM. Her serum was positive for the anti-MDA-5 antibody. Combination therapy with corticosteroids, immunosuppressants, and direct hemoperfusion using polymyxin B-immobilized fiber column (PMX-DHP) improved her respiratory dysfunction...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27994925/acute-eosinophilic-pneumonia-with-respiratory-failure-induced-by-synthetic-cannabinoid-inhalation
#17
Nesrin Öcal, Deniz Doğan, Ali Fuat Çiçek, Orhan Yücel, Ergun Tozkoparan
BACKGROUND: In recent days, synthetic cannabinoid derivatives have become life threatening for young people. Here, we want to share a case of acute eosinophilic pneumonia triggered by inhalation of synthetic cannabinoid, new side effects of which are being detected day by day. CASE REPORT: A 21-year-old male, who had no history of pulmonary diseases, was admitted to the clinic with shortness of breath. His oxygen saturation was measured as 85-86% in room air. Common irregular ground-glass opacities were observed in thorax radiology...
November 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27974986/primary-pulmonary-meningioma-simulating-a-pulmonary-metastasis
#18
Chun-Mao Juan, Mei-Ling Chen, Shang-Yun Ho, Yuan-Chun Huang
Primary pulmonary meningiomas represent a rare tumor entity. Few cases have been reported in the English medical literature, and they have almost all been solitary and benign in nature, with the exception of several extremely rare cases. We report herein a case of PPM that raised suspicion of a pulmonary metastatic tumor initially, as it was depicted as a single, round, small, ground-glass opacity pulmonary nodule on a chest computed tomography scan, in a 55-year-old man with a history of buccal cancer. Increased awareness of the clinical and radiologic characteristics of this rare category can assist a multidisciplinary team to perform adequate management...
2016: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/27966426/-lamotrigine-induced-pneumonitis
#19
Helle Dall Madsen, Jesper Rømhild Davidsen
A 28-year-old woman diagnosed with schizophrenia was admitted to hospital due to progressing dyspnoea for months. At admission, she was oxygen-dependent, and a high-resolution computed tomography revealed ground glass opacities. She had no obvious exposures besides having been treated with lamotrigine for several years. A psychiatrist doubted the diagnosis, and the lamotrigine treatment was tapered. After some months, she became clinically stable without further need of oxygen. Lamotrigine can cause pneumonitis, and this side effect should be suspected in patients who are being treated with lamotrigine and presenting with progressive dyspnoea...
December 12, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27959840/-clinical-manifestations-of-organizing-pneumonia
#20
Martín Hunter, Ana Ludueña, Irene Telias, Patricia Aruj, Silvia Rausch, Juan Pablo Suárez
Organizing pneumonia is a clinical entity asociated with nonspecific symptoms and radiological findings and abnormalities in pulmonary function tests. It is defined by the characteristic histopathological pattern: filling of alveoli and respiratory bronchioles by plugs of granulation tissue. It can be idiopathic (COP) or secondary to other causes (SOP). It is an unusual finding and the clinical and radiographic findings are nonspecific. For specific diagnosis an invasive procedure has to be done, but often empirical treatment is started when there's a clinical suspicion...
2016: Medicina
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