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Pelvic prolapse

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https://www.readbyqxmd.com/read/27922684/excess-mechanical-stress-and-hydrogen-peroxide-remodel-extracellular-matrix-of-cultured-human-uterosacral-ligament-fibroblasts-by-disturbing-the-balance-of-mmps-timps-via-the-regulation-of-tgf%C3%A2-%C3%AE-1-signaling-pathway
#1
Qifan Zhang, Cheng Liu, Shasha Hong, Jie Min, Qing Yang, Ming Hu, Yang Zhao, Li Hong
The regulation of the extracellular matrix (ECM) by mechanical stress is of interest as the ECM is essential in the development of pelvic organ prolapse. In the present study, the effect of overexposure to mechanical stress on the ECM, and the probable underlying mechanisms in cultured human uterosacral ligament fibroblasts (hUSLFs), was explored. Mechanical stress has an effect on oxidation‑antioxidation products in parametrial ligament fibroblasts. Thus, hUSLFs were incubated with different concentrations of hydrogen peroxide to elucidate any potential interactions...
December 6, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27919731/nerve-sparing-laparoscopic-colposacropexy-using-a-percutaneous-surgical-system-a-case-report
#2
Federico Romano, Francesco Legge, Giovanni Scambia, Maurizio Guido
STUDY OBJECTIVE: To evaluate the feasibility, efficacy and safeness of nerve-sparing laparoscopic colposacropexy performed with a minimally invasive approach by using 2,9 mm Percuvance(TM) Percutaneous Surgical System (PSS) (The Percuvance(TM) System, Teleflex Inc., USA). DESIGN: Step-by-step video demonstration of the surgical technique. The Internal Department Committee approved this study. The patient was adequately informed about the possible risks and benefits of this experimental technique and a written consent agreeing to undergo the described procedure was signed...
December 2, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27919131/-an-intravesical-foreign-body-after-caesarean-section-and-tissue-fixing-system-tfs-operation-two-case-reports
#3
Kohei Mori, Masahiro Yanagisawa, Kotaro Hirai
Foreign body in the bladder is a relatively rare case. We encountered two cases of foreign bodies in the bladder after gynecological surgery. Case 1 was a 72-year-old woman. When she was 70 years old,an operation for her pelvic organ prolapse was performed. She visited our hospital because of discomfort in urination. We performed a transurethral lithotripsy of the bladder stone and detected a foreign body,and it was an anchor used for the Tissue Fixation System(TFS)operation (a pelvic organ prolapse operation)...
October 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27918338/female-pelvic-medicine-and-reconstructive-surgery-in-canada-a-survey-of-obstetrician-gynecologists-and-urologists
#4
Marie K Christakis, Eliane M Shore, Ariel Pulver, Colleen D McDermott
OBJECTIVE: The aim of this study was to assess the current status of female pelvic medicine and reconstructive surgery (FPMRS) in Canada, including level of training, practice patterns, barriers to practice and opinions among obstetrician-gynecologists (OB/GYNs) and urologists. METHODS: Electronic surveys were distributed to 737 OB/GYNs through the Society of Obstetricians and Gynaecologists of Canada and to 489 urologists through the Canadian Urological Association...
December 1, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27902953/rectal-free-perforation-after-stapled-hemorrhoidopexy-a-case-report-of-laparoscopic-peritoneal-lavage-and-repair-without-stoma
#5
Seokyong Ryu, Byung-Noe Bae
INTRODUCTION: Stapled hemorrhoidopexy is widely performed for treatment of prolapsed hemorrhoids because of advantages, including shorter hospital stay and less discomfort, compared with conventional hemorrhoidectomy. However, it can have severe adverse effects, such as rectal bleeding, perforation, and sepsis. PRESENTATION OF CASE: We report the case of a healthy 28-year-old man who presented to the emergency department with sudden-onset diffuse abdominal pain and hematochezia...
November 21, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27902825/association-between-the-amount-of-vaginal-mesh-used-with-mesh-erosions-and-repeated-surgery-after-repairing-pelvic-organ-prolapse-and-stress-urinary-incontinence
#6
Bilal Chughtai, Matthew D Barber, Jialin Mao, James C Forde, Sharon-Lise T Normand, Art Sedrakyan
Importance: Mesh, a synthetic graft, has been used in pelvic organ prolapse (POP) repair and stress urinary incontinence (SUI) to augment and strengthen weakened tissue. Polypropylene mesh has come under scrutiny by the US Food and Drug Administration. Objective: To examine the rates of mesh complications and invasive reintervention after the placement of vaginal mesh for POP repair or SUI surgery. Design, Setting, and Participants: This investigation was an observational cohort study at inpatient and ambulatory surgery settings in New York State...
November 30, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27900993/corrigendum-porcine-small-intestinal-submucosa-mesh-for-treatment-of-pelvic-organ-prolapsed
#7
(no author information available yet)
[This corrects the article DOI: 10.4103/0366-6999.192784.].
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27900401/vaginal-wall-weakness-in-parous-ewes-a-potential-preclinical-model-of-pelvic-organ-prolapse
#8
Natharnia Young, Anna Rosamilia, John Arkwright, Joseph Lee, Miranda Davies-Tuck, Joan Melendez, Jerome Werkmeister, Caroline E Gargett
INTRODUCTION AND HYPOTHESIS: Ewes develop pelvic organ prolapse (POP) and may be a suitable model for preclinical studies evaluating cell-based therapies for POP. The aim of this study was to establish a clinical score of vaginal weakness and to compare POP Quantification System (POP-Q) values in conscious nulliparous and parous ewes and determine whether ewes are a suitable POP model. METHODS: Ewes (n = 114) were examined while conscious, without sedation, and standing in a V conveyer by adapting the human POP-Q measurement...
November 29, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27898453/resolution-of-rectal-prolapse-by-vaginal-reconstruction
#9
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: Rectal prolapse is a disorder of the pelvic floor in which the layers of the rectal mucosa protrude outward through the anus. Surgical repair is the mainstay of treatment. Options include intra-abdominal procedures such as rectopexy and perineal procedures such as the Delorme and Altemeier perineal rectosigmoidectomy. Rectal and vaginal prolapse can often coexist. However, to our knowledge, there are no reported cases of rectal prolapse resolved by the repair of a compressive enterocele abutting the anterior rectal wall through a vaginal approach alone...
November 28, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27896472/safety-and-perioperative-morbidity-of-laparoscopic-sacropexy-a-systematic-analysis-and-a-comparison-with-laparoscopic-hysterectomy
#10
R Joukhadar, S Baum, J Radosa, C Gerlinger, A Hamza, I Juhasz-Böss, E-F Solomayer
PURPOSE: The high prevalence of Pelvic Organ Prolapse (POP) along with the demographic trend of the ageing population raises the value of sacropexy in the treatment of POP. Thus, efforts to decrease risks associated with this procedure have the potential for public health impact. We examined the perioperative morbidity of laparoscopic sacropexy regarding the surgical access and compared it with the morbidity of one of the most common gynecological procedure, the laparoscopic hysterectomy...
November 28, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27894034/quality-of-life-after-uphold%C3%A2-vaginal-support-system-surgery-for-apical-pelvic-organ-prolapse-a-prospective-multicenter-study
#11
Päivi Rahkola-Soisalo, Daniel Altman, Christian Falconer, Edward Morcos, Martin Rudnicki, Tomi S Mikkola
OBJECTIVE: To study the effects on quality of life in women operated for apical pelvic organ prolapse using the Vaginal Uphold™ System. STUDY DESIGN: In this prospective cohort study, women (n=207) with symptomatic apical prolapse, with or without cystocele, were operated using the Uphold™ Vaginal Support System. Follow-up for quality of life was performed at 12 months after surgery, and assessed by the PFDI-20, and PFIQ-7, and sexual function by the PISQ-12...
November 14, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27886523/two-years-follow-up-of-270-patients-treated-by-transvaginal-mesh-for-anterior-and-or-apical-prolapse
#12
Florence Hugele, Laure Panel, Camille Farache, Amgad Kashef, Arnaud Cornille, Christophe Courtieu
OBJECTIVE: The aim of this study was to assess the 1 and 2 years outcomes of transvaginal single incision mesh surgery (SIMS) for anterior pelvic organ prolapse (POP). MATERIAL AND METHODS: This was a prospective study including all patients from November 2008 to December 2012 who underwent SIMS for symptomatic anterior prolapse stage≥2, according to the POP Quantification (POP-Q). Symptoms and quality of life were assessed using validated questionnaires: Pelvic Floor Distress Inventory (PFDI-20), Pelvic Floor Impact questionnaire (PFIQ-7), and Prolapse/Incontinence Sexual Questionnaire (PISQ-12)...
November 11, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27882016/sacrohysteropexy-performed-as-uterus-conserving-surgery-for-pelvic-organ-prolapse-review-of-case-files
#13
Ayesha Khan, Riffat Jaleel, Farah Deeba Nasrullah
OBJECTIVE: To assess the outcome and safety of sacrohysteropexy as uterus conserving surgery for pelvic organ prolapse in young women and to assess patients' satisfaction with the procedure. METHODS: This is a case series of patients operated at Sind Government Lyari General Hospital and Civil Hospital Karachi, between January, 2007 to October, 2015. Data of the patients who had sacrohysteropexy were reviewed. Complications during surgery and post-operative period including haemorrhage, visceral injury, paralytic ileus and peritonitis were studied...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27872979/evaluation-of-isolated-urinary-stress-incontinence-according-to-the-type-of-levator-ani-muscle-lesion-using-3-4d-transperineal-ultrasound-36%C3%A2-months-post-partum
#14
José Antonio García Mejido, Pamela Valdivieso Mejias, Ana Fernández Palacín, María José Bonomi Barby, Paloma De la Fuente Vaquero, José Antonio Sainz Bueno
INTRODUCTION: Vaginal delivery can lead to pelvic floor disorders. Many authors have described pelvic floor injuries that can predict future defects such as urinary incontinence and pelvic organ prolapse. We propose the assessment of urinary stress incontinence and its association with levator ani muscle (LAM) microtrauma (>20% in the levator hiatus area during Valsalva) and macrotraumas (avulsion) identified by 3/4D transperineal ultrasound (3D-TpUS) 36 months post-partum. MATERIALS AND METHODS: This was a prospective observational study including 168 nulliparous women...
November 21, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27871954/surgical-management-for-pelvic-organ-prolapse-and-its-impact-on-sexual-function
#15
REVIEW
Jennifer C Thompson, Rebecca G Rogers
INTRODUCTION: Female sexual function is complex, incorporating physical, emotional, and psychological factors. Pelvic organ prolapse, descent of the pelvic organs to or through the vaginal opening, is a common condition that affects quality of life, including sexual function. Symptomatic prolapse is most commonly treated with reconstructive surgery. AIM: To address the surgical management of pelvic organ prolapse and its impact on sexual function and include recommendations for evaluating sexual function, use of validated questionnaires to assess function, preoperative counseling, and postoperative follow-up...
July 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27870169/comparison-of-dynamic-magnetic-resonance-defecography-with-rectal-contrast-and-conventional-defecography-for-posterior-pelvic-floor-compartment-prolapse
#16
Jan J van Iersel, Hendrik A Formijne Jonkers, Paul M Verheijen, Ivo A M J Broeders, Ben G F Heggelman, Vicknesh Sreetharan, Jurgen J Fütterer, Inne Somers, Marloes van der Leest, Esther C J Consten
AIM: The study compared the diagnostic capabilities of dynamic magnetic resonance defecography (D-MRI) with conventional defecography (CD, reference standard) in patients with symptoms of prolapse of the posterior compartment of the pelvic floor. METHOD: Forty-five consecutive patients underwent CD and D-MRI. Outcome measures were the presence or absence of rectocele, enterocele, intussusception, rectal prolapse and the descent of the anorectal junction on straining measured in millimetres...
November 21, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27866958/use-of-concomitant-stress-incontinence-surgery-at-time-of-pelvic-organ-prolapse-surgery-since-release-of-the-2011-fda-health-notification-on-serious-complications-associated-with-transvaginal-mesh
#17
Alice Drain, Aqsa Khan, Erin L Ohmann, Benjamin M Brucker, Scott Smilen, Nirit Rosenblum, Victor W Nitti
PURPOSE: There is controversy regarding performing concomitant anti-incontinence procedures at the time of pelvic organ prolapse (POP) repair. Data supports improvement in stress urinary incontinence (SUI) with concomitant sling, but increased adverse events. We assessed trends in preoperative SUI evaluation, concomitant anti-incontinence procedure at POP surgery, and post-operative anti-incontinence procedures at our institution before and after the 2011 FDA Public Health Notification pertaining to vaginal mesh...
November 17, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27865942/outcomes-of-laparoscopic-sacropexy-in-women-over-70-a-comparative-study
#18
Anne Sophie Boudy, Thibault Thubert, Marie Vinchant, Jean François Hermieu, Vincent Villefranque, Xavier Deffieux
OBJECTIVE: Precise data are lacking concerning laparoscopic sacropexy in the elderly population. The purpose of this study was to compare the outcomes and complications associated with laparoscopic sacropexy (colpopexy or hysteropexy) in women aged under 70 and 70 or over. STUDY DESIGN: Retrospective review of data on patients who underwent laparoscopic sacropexy in two tertiary centers. Peri- and postoperative complications were recorded and described using the IUGA classification...
November 11, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27865742/internal-rectal-prolapse-definition-assessment-and-management-in-2016
#19
L Cariou de Vergie, A Venara, E Duchalais, E Frampas, P A Lehur
Internal rectal prolapse (IRP) is a well-recognized pelvic floor disorder mainly seen during defecatory straining. The symptomatic expression of IRP is complex, encompassing fecal continence (56%) and/or evacuation disorders (85%). IRP cannot be characterized easily by clinical examination alone and the emergence of dynamic defecography (especially MRI) has allowed a better comprehension of its pathophysiology and led to the proposition of a severity score (Oxford score) that can guide management. Decision for surgical management should be multidisciplinary, discussed after a complete work-up, and only after medical treatment has failed...
November 16, 2016: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/27858132/ligament-shortening-compared-to-vaginal-colpopexy-at-the-time-of-hysterectomy-for-pelvic-organ-prolapse
#20
Pamela S Fairchild, Neil S Kamdar, Emily R Rosen, Carolyn W Swenson, Dee E Fenner, John O DeLancey, Daniel M Morgan
INTRODUCTION AND HYPOTHESIS: The performance of a colpopexy at the time of hysterectomy for pelvic organ prolapse is a potential indicator of surgical quality. However, vaginal colpopexy has not been directly compared with the classic technique of ligament shortening and reattachment. We sought to test the null hypothesis that there is no difference in prolapse recurrence between the techniques. METHODS: We performed a retrospective chart review of 330 vaginal hysterectomies performed for prolapse, comparing symptomatic and/or anatomic recurrence rates between patients having a vaginal colpopexy (uterosacral ligament suspension or sacrospinous ligament suspension) and those having ligament shortening and reattachment...
November 17, 2016: International Urogynecology Journal
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