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https://www.readbyqxmd.com/read/27917809/autonomic-cardiac-activity-in-patients-with-smoking-and-alcohol-addiction-by-heart-rate-variability-analysis
#1
Ramazan Yuksel, Rabia Nazik Yuksel, Tijen Sengezer, Senol Dane
PURPOSE: Smoking and alcohol addictions are common and worldwide. In the present study, we aimed to investigate the effects of these addictions on cardiac rhythm using heart rate variability (HRV) analysis. METHODS: Addicts (n=42 men: 22 cigarette; 20 cigarette and alcohol) and age-matched controls (n=34 men) were included in the study. All patients fulfill the criteria for dependence according to DSM-IV-TR. Electrocardiography (ECG) recordings were obtained for a total of 30 minutes...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917437/nicotine-plus-a-high-fat-diet-triggers-cardiomyocyte-apoptosis
#2
Indrani Sinha-Hikim, Theodore C Friedman, Mark Falz, Victor Chalfant, Mohammad Kamrul Hasan, Jorge Espinoza-Derout, Desean L Lee, Carl Sims, Peter Tran, Sushil K Mahata, Amiya P Sinha-Hikim
Cigarette smoking is an important risk factor for diabetes, cardiovascular disease and non-alcoholic fatty liver disease. The health risk associated with smoking can be aggravated by obesity. Smoking might also trigger cardiomyocyte (CM) apoptosis. Given that CM apoptosis has been implicated as a potential mechanism in the development of cardiomyopathy and heart failure, we characterize the key signaling pathways in nicotine plus high-fat diet (HFD)-induced CM apoptosis. Adult C57BL6 male mice were fed a normal diet (ND) or HFD and received twice-daily intraperitoneal (IP) injections of nicotine (0...
December 5, 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27905916/study-protocol-a-dose-escalating-phase-2-study-of-oral-lisdexamfetamine-in-adults-with-methamphetamine-dependence
#3
Nadine Ezard, Adrian Dunlop, Brendan Clifford, Raimondo Bruno, Andrew Carr, Alexandra Bissaker, Nicholas Lintzeris
BACKGROUND: The treatment of methamphetamine dependence is a continuing global health problem. Agonist type pharmacotherapies have been used successfully to treat opioid and nicotine dependence and are being studied for the treatment of methamphetamine dependence. One potential candidate is lisdexamfetamine, a pro-drug for dexamphetamine, which has a longer lasting therapeutic action with a lowered abuse potential. The purpose of this study is to determine the safety of lisdexamfetamine in this population at doses higher than those currently approved for attention deficit hyperactivity disorder or binge eating disorder...
December 1, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27904164/consequences-and-possible-predictors-of-health-damaging-behaviors-and-mental-health-problems-in-pregnancy-a-review
#4
REVIEW
F Ulrich, F Petermann
In recent decades, the understanding of the short and longer term effects of health-damaging behaviors and mental health problems in pregnant women and the underlying mechanisms of these behaviors and illnesses has significantly increased. In contrast, little is known about the factors affecting individual pregnant women which contribute to health-damaging behaviors and mental illness. The aim of this paper was therefore to summarize the current state of research into the consequences of nicotine and alcohol consumption, malnutrition, excessive weight gain or obesity, and impaired mental health (depression and anxiety) during pregnancy...
November 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27901240/prevalence-of-chronic-spinal-pain-and-identification-of-associated-factors-in-a-sample-of-the-population-of-s%C3%A3-o-paulo-brazil-cross-sectional-study
#5
Jidiene Dylese Presecatan Depintor, Eduardo Sawaya Botelho Bracher, Dayane Maia Costa Cabral, José Eluf-Neto
CONTEXT AND OBJECTIVE: Chronic spinal pain, especially low-back pain and neck pain, is a leading cause of years of life with disability. The aim of the present study was to estimate the prevalence of chronic spinal pain among individuals aged 15 years or older and to identify the factors associated with it. DESIGN AND SETTING: Cross-sectional epidemiological study on a sample of the population of the city of São Paulo. METHOD: Participants were selected using random probabilistic sampling and data were collected via face-to-face interviews...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27891376/smokeless-tobacco-and-stroke-a-clinico-epidemiological-follow-up-study-in-a-tertiary-care-hospital
#6
Subhransu Sekhar Jena, Shobhitendu Kabi, Baikuntha Nath Panda, B C Kameswari, Payal, Ishwar Chandra Behera, Subrat Kumar Tripathy, Seemanchana Mahanta
INTRODUCTION: Among the modifiable risk factors for stroke, tobacco smoking is well recognized. In some studies the use of Smokeless Tobacco (ST) has also been contributed as a risk factor for ischemic stroke. Use of ST is very common in South-East Asia. The form of ST varies according to the geographical and cultural variation. AIM: To study the various clinical symptoms and radiological findings of stroke due to different types of ST. MATERIALS AND METHODS: This was a prospective hospital based study carried out over a period of 2 years...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27878808/interventions-for-tobacco-use-cessation-in-people-in-treatment-for-or-recovery-from-substance-use-disorders
#7
REVIEW
Dorie Apollonio, Rose Philipps, Lisa Bero
BACKGROUND: Smoking rates in people with alcohol and other drug dependencies are two to four times those of the general population. Concurrent treatment of tobacco dependence has been limited due to concern that these interventions are not successful in this population or that recovery from other addictions could be compromised if tobacco cessation was combined with other drug dependency treatment. OBJECTIVES: To evaluate whether interventions for tobacco cessation are associated with tobacco abstinence for people in concurrent treatment for or in recovery from alcohol and other drug dependence...
November 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27864080/alterations-of-resting-state-functional-network-connectivity-in-the-brain-of-nicotine-and-alcohol-users
#8
Victor M Vergara, Jingyu Liu, Eric D Claus, Kent Hutchison, Vince Calhoun
Alcohol and nicotine intake result in neurological alterations at the circuit level. Resting state functional connectivity has shown great potential in identifying these alterations. However, current studies focus on specific seeds and leave out many brain regions where effects might exist. The present study uses a data driven technique for brain segmentation covering the whole brain. Functional magnetic-resonance-imaging (fMRI) data were collected from 188 subjects:51 non-substance consumption controls (CTR), 36 smoking-and-drinking subjects (SAD), 28 drinkers (DRN), and 73 smokers (SMK)...
November 15, 2016: NeuroImage
https://www.readbyqxmd.com/read/27856998/tobacco-industry-use-of-flavourings-to-promote-smokeless-tobacco-products
#9
Ganna Kostygina, Pamela M Ling
BACKGROUND: While fruit, candy and alcohol characterising flavours are not allowed in cigarettes in the USA, other flavoured tobacco products such as smokeless tobacco (ST) continue to be sold. We investigated tobacco manufacturers' use of flavoured additives in ST products, the target audience(s) for flavoured products, and marketing strategies promoting products by emphasising their flavour. METHODS: Qualitative analysis of internal tobacco industry documents triangulated with data from national newspaper articles, trade press and internet...
November 2016: Tobacco Control
https://www.readbyqxmd.com/read/27848217/pregabalin-for-the-treatment-of-drug-and-alcohol-withdrawal-symptoms-a-comprehensive-review
#10
REVIEW
Rainer Freynhagen, Miroslav Backonja, Stephan Schug, Gavin Lyndon, Bruce Parsons, Stephen Watt, Regina Behar
Treatments for physical dependence and associated withdrawal symptoms following the abrupt discontinuation of prescription drugs (such as opioids and benzodiazepines), nicotine, alcohol, and cannabinoids are available, but there is still a need for new and more effective therapies. This review examines evidence supporting the potential use of pregabalin, an α2δ voltage-gated calcium channel subunit ligand, for the treatment of physical dependence and associated withdrawal symptoms. A literature search of the MEDLINE and Cochrane Library databases up to and including 11 December 2015 was conducted...
November 16, 2016: CNS Drugs
https://www.readbyqxmd.com/read/27844059/developmental-ethanol-exposure-leads-to-long-term-deficits-in-attention-and-its-underlying-prefrontal-circuitry
#11
Emma L Louth, Warren Bignell, Christine L Taylor, Craig D C Bailey
Chronic prenatal exposure to ethanol can lead to a spectrum of teratogenic outcomes that are classified in humans as fetal alcohol spectrum disorders (FASD). One of the most prevalent and persistent neurocognitive components of FASD is attention deficits, and it is now thought that these attention deficits differ from traditional attention deficit hyperactivity disorder (ADHD) in their quality and response to medication. However, the neuronal mechanisms underlying attention deficits in FASD are not well understood...
September 2016: ENeuro
https://www.readbyqxmd.com/read/27834390/varenicline-reduces-context-induced-relapse-to-alcohol-seeking-through-actions-in-the-nucleus-accumbens
#12
F Lacroix, A Pettorelli, J-Mn Maddux, A Heidari-Jam, N Chaudhri
Varenicline, a pharmacotherapy for tobacco addiction, reduces alcohol consumption in humans and rodents. The therapeutic potential of varenicline would escalate if it also diminished conditioned responses elicited by alcohol-predictive cues, which can precipitate relapse in abstinent individuals. We investigated this application, along with the underlying neural substrates, using a robust preclinical assay in which relapse to alcohol-seeking was triggered by re-exposure to an alcohol-associated environmental context...
November 11, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27833223/psychiatric-comorbidity-and-physical-correlates-in-alcohol-dependent-patients
#13
Deepak Gauba, Pramod Thomas, Yatan P S Balhara, Smita N Deshpande
AIM: To examine the prevalence and pattern of comorbidity in alcohol dependence and its relationship with physical and laboratory findings. MATERIALS AND METHODS: Eighty males with alcohol dependence were examined using the Hindi version of Diagnostic Interview for Genetic Studies, the International Classification of Disease-10(th) Edition Personality Disorder Examination, Alcohol Use Disorder Identification Test for alcohol use, global assessment of functioning, blood sampling electrocardiogram, and ultrasonogram...
September 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/27828712/effects-of-t-ai-chi-on-serotonin-nicotine-dependency-depression-and-anger-in-hospitalized-alcohol-dependent-patients
#14
Chung-Uk Oh, Nam-Cho Kim
OBJECTIVES: The aim of this study was to investigate the effects of t'ai chi on blood serotonin levels, nicotine dependence, depression, and anger in hospitalized alcohol-dependent patients. METHOD: This study followed an experimental and nonequivalent control group in a non-synchronized design. It was performed in a hospital located in Young Ju city, Korea, from April to August 2013. Thirty-eight patients who were hospitalized with alcohol dependence were included...
November 9, 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27826631/determination-of-volatile-organic-compounds-including-alcohols-in-refill-fluids-and-cartridges-of-electronic-cigarettes-by-headspace-solid-phase-micro-extraction-and-gas-chromatography-mass-spectrometry
#15
Hyun-Hee Lim, Ho-Sang Shin
An analytical method for the detection of 14 volatile organic compounds (VOCs) was developed to investigate VOCs in refill fluids and cartridges of electronic cigarettes (EC) using headspace solid-phase micro extraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). In total, 14 VOCs were identified and quantified in 283 flavored liquids, 21 nicotine liquids, and 12 disposable cartridges. The detected concentration ranges of the VOCs are as follows: benzene (0.008-2.28 mg L(-1)), toluene (0...
November 9, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27816041/nicotine-dependence-and-sleep-quality-in-young-adults
#16
E N Dugas, M P Sylvestre, E K O'Loughlin, J Brunet, L Kakinami, E Constantin, J O'Loughlin
INTRODUCTION: More cigarette smokers report poor sleep quality than non-smokers, but the association between nicotine dependence (ND) and sleep quality has not been well-characterized. The objective of this study was to describe the associations among frequency and intensity of cigarette smoking, ND symptoms, and sleep quality in young adults. METHODS: Data on past-year smoking frequency, number of cigarettes smoked in the past month, five ND indicators (i.e., withdrawal, craving, self-medication symptoms, mFTQ, ICD-10 criteria for tobacco dependence), and sleep quality (measured with the Pittsburgh Sleep Quality Index (PSQI)) were collected in 2011-12 in self-report questionnaires completed by 405 young adult smokers (mean age 24 (0...
February 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/27809671/a-systematic-review-of-the-relationship-between-psychological-disorders-or-substance-use-and-self-reported-cognitive-failures
#17
Nicole Carrigan, Emma Barkus
INTRODUCTION: Cognitive failures are errors in normal everyday functioning. Individuals with psychological disorders may possess heightened vulnerability. We sought to review the literature on cognitive failures in psychological disorders to determine the nature of this association, and whether failures relate to neuropsychological performance. We also examine the relationship between cognitive failures and substance use since it is relevant to everyday cognition and co-occurs in many psychological disorders...
November 3, 2016: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/27801793/identification-of-vape-shops-in-two-north-carolina-counties-an-approach-for-states-without-retailer-licensing
#18
Joseph G L Lee, Heather D'Angelo, Jaleel D Kuteh, Ryan J Martin
Stores that sell electronic nicotine delivery systems (ENDS) as their primary product are a new phenomenon and often termed "vape shops". While vape shops are now regulated by state and federal agencies, not all states maintain lists of vape shops in operation. Standard ways of identifying tobacco retailers through off-premise alcohol permits and business listing services may not identify vape shops. We used four online business listing services (i.e., Google Maps, ReferenceUSA, YellowPages.com, Yelp) to identify vape shops in two counties in North Carolina (NC)...
October 27, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27801766/cessation-of-smoking-and-alcohol-addiction-following-thalamic-hemorrhage
#19
Fatima Najeeb, Brian Silver, Muhib Khan
INTRODUCTION: We describe a case of thalamic intracerebral hemorrhage leading to cessation of smoking. CASE REPORT: A 53-year-old female presented to the emergency department with right-sided weakness and dysarthria. Initial systolic blood pressure was 220 mm Hg. Computed tomography scan showed a left thalamic hemorrhage with associated edema and hemorrhage extending into the left lateral and third ventricle. She recovered uneventfully and was discharged to inpatient rehabilitation and eventually transitioned home...
November 2016: Neurologist
https://www.readbyqxmd.com/read/27796078/withdrawal-from-chronic-nicotine-exposure-produces-region-specific-tolerance-to-alcohol-stimulated-glua1-phosphorylation
#20
M Adrienne McGinn, Rod I Paulsen, Christy A Itoga, Muhammad A Farooq, Jonathan E Reppel, Kimberly N Edwards, Annie M Whitaker, Nicholas W Gilpin, Scott Edwards
BACKGROUND: Nicotine use increases alcohol drinking, suggesting that the combination of these drugs may produce synergistic effects in activating reward circuitry. Alternatively, use of either of these drugs may facilitate the development of cross-tolerance to the other to promote intake escalation. METHODS: In this study, adult male Wistar rats were chronically exposed to room air or chronic, intermittent nicotine vapor, which has been shown to produce symptoms of nicotine dependence as evidenced by elevated nicotine self-administration and a host of somatic and motivational withdrawal symptoms...
December 2016: Alcoholism, Clinical and Experimental Research
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