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https://www.readbyqxmd.com/read/28074465/effects-of-alpha-lipoic-acid-on-ischemia-reperfusion-injury-in-rat-hindlimb-ischemia-model
#1
Arif Aydın, Alpagan Mustafa Yıldırım
BACKGROUND: This study was performed to evaluate the effect of alpha lipoic acid (ALA) on prevention of ischemia-reperfusion (IR) injury in rat hindlimb ischemia model. METHODS: Forty male Sprague Dawley rats weighing between 250 and 300 g were divided into 4 groups of 10 rats. Hindlimb composite island flaps were raised in all rats. Clamps were applied to femoral vessels of all subjects, but immediately released without causing ischemia in Group 1. In Group 2, after 4 hours of ischemia, 24 hours of reperfusion was performed...
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28061517/supraclavicular-flap-reconstruction-of-cutaneous-defects-has-lower-complication-rate-than-mucosal-defects
#2
Sameep Kadakia, Jay Agarwal, Moustafa Mourad, Sara Ashai, Thomas Lee, Yadranko Ducic
Background The objective of this study was to determine whether there was a difference in complication rate between cutaneous and mucosal defects reconstructed with the supraclavicular artery flap. Methods Retrospective review of postoperative complications in 63 patients from 2008 to 2015 with cutaneous and mucosal head and neck defects following oncologic ablation reconstructed with the supraclavicular flap, with a minimum follow-up duration of 6 months. Of the 63 patients, 38 patients had cutaneous defects, whereas 25 had mucosal defects...
January 6, 2017: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/28060171/broader-practice-indications-for-mohs-surgical-defect-healing-by-secondary-intention-a-survey-study
#3
Chetan Vedvyas, Patricia L Cummings, Roy G Geronemus, Jeremy A Brauer
BACKGROUND: Recent reports have indicated secondary intention (SI) healing utilization for Mohs surgical defects beyond conventionally accepted indications. OBJECTIVE: To characterize potentially more expansive guidelines for when SI healing is indicated or appropriate in dermatologic surgery. METHODS: A survey study was e-mailed to the American College of Mohs Surgery in 2015. A group of 293 respondents addressed factors influencing decisions to heal surgical defects secondarily...
December 29, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28058777/platysma-sparing-vascularized-submental-lymph-node-flap-transfer-for-extremity-lymphedema
#4
Igor Poccia, Chia-Yu Lin, Ming-Huei Cheng
BACKGROUND AND OBJECTIVES: Due to its consistent vascular and lymphatic anatomy, the vascularized submental lymph node flap is a reliable option for lymphedema treatment. Despite these advantages, flap harvest requires resection of platysma, which may cause a marginal mandibular nerve pseudo-paralysis. The aim of this study was to investigate the donor site morbidity of an innovative platysma-sparing vascularized submental lymph node flap transfer for treating extremity lymphedema. METHODS: Ten patients undergoing platysma sparing submental lymph-node flap harvest were prospectively enrolled in the study and compared with a control group of 10 patients who underwent standard submental lymph-node flap harvest...
January 6, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28053377/feasibility-of-type-iii-venous-flap-in-coverage-of-hand-defects-following-trauma-and-burns
#5
Pawan Agarwal, Ambuj Kumar, Dhananjaya Sharma
INTRODUCTION: venous flaps are alternative reconstructive option for coverage of defects. They are nourished by venous blood flow or by arterial blood flowing through the venous network. This study was conducted to assess the feasibility of venous flap in coverage of extremities defects following trauma and burns. MATERIAL AND METHODS: Over a period of one year, 15 arterialized venous flaps were applied to skin defects of the hand. Postoperatively flap were monitored for survival and patients followed up for three months...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28052826/a-systematic-review-and-comparison-of-outcomes-following-simple-syndactyly-reconstruction-with-skin-grafts-or-a-dorsal-metacarpal-advancement-flap
#6
Matthew A Sullivan, Joshua M Adkinson
PURPOSE: Many techniques exist for simple syndactyly reconstruction. The most commonly used techniques involve either skin grafts or a dorsal metacarpal advancement flap. Our aim was to review and compare the outcomes of these 2 techniques systematically. METHODS: We reviewed articles from PubMed, MEDLINE, EMBASE, and Google Scholar published between January 1966 and January 2016. We identified studies that reported outcomes after reconstruction of simple syndactyly using skin grafts and those using only a dorsal metacarpal advancement flap...
January 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28052381/the-lateral-calcaneal-artery-as-an-alternative-recipient-vessel-option-for-heel-and-lateral-foot-reconstruction
#7
Kyong-Je Woo, Jin-Woo Park, Goo-Hyun Mun
BACKGROUND: Clinical outcomes of consecutive use of the lateral calcaneal artery (LCA) as a recipient vessel for microsurgical reconstruction have not been reported. This study aimed to evaluate the feasibility and safety of the LCA as a recipient vessel for microsurgical foot reconstruction based on anatomical study of CT angiography and clinical results of using this vessel as the recipient. METHODS: Anatomic study was performed using CT angiography of 61 lower extremities (31 patients)...
January 4, 2017: Microsurgery
https://www.readbyqxmd.com/read/28050062/reliability-of-the-pectoralis-major-myocutaneous-flap-in-reconstructive-oral-cancer-surgery-in-developing-countries-our-experience
#8
Atanu Bhanja, D S J D'Souza, Collin Roy, R N Poddar
BACKGROUND: Although free flaps are nowadays considered 'Gold standard' of head and neck reconstruction, pectoralis major myocutaneous (PMMC) flap is still popular among many reconstructive cancer surgeons in developing countries for its many advantages and also due to lack of resources for free flaps in most of the centers, large number of cancer patients with poor nutritional status and economic condition. However, many studies have reported high complication rate in PMMC flap. So, the purpose of our study was to evaluate the reliability of PMMC flap...
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28045815/reconstruction-of-skin-defects-on-the-mid-and-lower-face-using-expanded-flap-in-the-neck
#9
Xiaogen Hu, Gao Zeng, Yang Zhou, Cheng Sun
BACKGROUND: The reconstruction of major burn and other deformities resulting from significant soft tissue deficits of the face is a continuing challenge for surgeons. In the study, the authors introduce our 5-year experiences using expanded flap in the neck for reconstruction on the mid and lower face. METHODS: From 2008 and 2013, 12 tissue expanders were used in 12 patients for face resurfacing. The operation consisted of 2 steps. In the first step, the expander was placed subcutaneously under the skin of the neck and they were expanded timely to create adequate superfluous skin and soft tissue...
December 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28042321/pre-vascularization-enhances-therapeutic-effects-of-human-mesenchymal-stem-cell-sheets-in-full-thickness-skin-wound-repair
#10
Lei Chen, Qi Xing, Qiyi Zhai, Mitchell Tahtinen, Fei Zhou, Lili Chen, Yingbin Xu, Shaohai Qi, Feng Zhao
Split thickness skin graft (STSG) implantation is one of the standard therapies for full thickness wound repair when full thickness autologous skin grafts (FTG) or skin flap transplants are inapplicable. Combined transplantation of STSG with dermal substitute could enhance its therapeutic effects but the results remain unsatisfactory due to insufficient blood supply at early stages, which causes graft necrosis and fibrosis. Human mesenchymal stem cell (hMSC) sheets are capable of accelerating the wound healing process...
2017: Theranostics
https://www.readbyqxmd.com/read/28041753/modified-reversed-superficial-peroneal-artery-flap-in-the-reconstruction-of-ankle-and-foot-defects-following-severe-burns-or-trauma
#11
Shi-Ji Li, Hao Cheng, Xu Fang, Jian-Yang Xu, Fei Wang, Sheng Liu, Xu-Lin Chen, Xiong-Wen Lv
OBJECTIVE: Challenges persist in the reconstruction of the ankle and the foot with exposed tendons, joints, and bones as a result of severe burns and trauma. In flap elevation involving the sensitive superficial nerve, the local nerve was always sacrificed to obtain an anesthetic donor site; however, such a procedure introduced the possibility of painful neuromas. In this study, we present a desired clinical application of a modified reversed superficial peroneal artery flap, in which the superficial peroneal nerve is preserved...
December 29, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28040452/delay-techniques-for-nipple-sparing-mastectomy-a-systematic-review
#12
REVIEW
Laurel S Karian, Paul J Therattil, Philip D Wey, Kevin T Nini
BACKGROUND: Rare but serious complications of nipple-sparing mastectomy (NSM) include necrosis of the nipple-areolar complex (NAC) and mastectomy skin flaps. NAC and mastectomy flap delay procedures are novel techniques designed to avoid these complications and may be combined with retroareolar biopsy as a first-stage procedure. We performed a systematic review of the literature to evaluate various techniques for NAC and mastectomy flap delay. METHODS: PubMed and Cochrane databases were searched from January 1975 through April 15, 2016...
November 29, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28040322/mucosectomy-impairs-ileal-microcirculation-and-results-in-flap-contraction-after-experimental-ileocystoplasty
#13
Raimondo M Cervellione, Daniel Hajnal, Gabreilla Varga, George Rakoczy, Jozsef Kaszaki, David Keene, Anju Goyal, Alan Dickson, Tamas Cserni
INTRODUCTION: Bladder augmentation with demucosalized ileal flap is a promising alternative approach for mucus free bladder augmentation; however, the contraction of the flap is still a major concern. It has been hypothesized that mucosectomy causes ischemic damage, but no direct histological evidence has been found and attention is now focused on the urothelium cover to prevent the exposure of the denuded surface to urine or the use of balloons to keep the flaps distended. OBJECTIVE: Our aim was to study the effect of mucosectomy on the microcirculation of ileal flaps during reverse clam ileocystoplasty using direct intraoperative imaging of the ileum...
November 29, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28039502/nipple-reconstruction-with-dorsal-skin-provides-better-projection-than-reconstruction-with-abdominal-or-breast-skin-with-cartilage-grafting
#14
Runa Mihara, Hiroki Mori, Mutsumi Okazaki
Nipple projection of a modified C-V flap with or without costal cartilage was compared on abdominal, breast, and dorsal skin. A total of 81 patients and 85 sites were studied. The nipple was reconstructed secondarily using a modified C-V flap. Patients were classified by breast mound skin into five groups: dorsal skin without cartilage (group A, n = 18); abdominal skin without cartilage (group B, n = 6); abdominal skin with cartilage (group C, n = 26); breast skin without cartilage (group D, n = 20); and breast skin with cartilage (group E, n = 15)...
December 30, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28039499/omega-%C3%AE-advancement-flap-a-circular-flap-design-for-the-aesthetic-closure-of-circular-skin-defect
#15
Enver Arpaci, Serdar Altun, Nilgün Markal Ertas, Ahmet Cagri Uysal, Emre Inozu
BACKGROUND: Most skin defects that require reconstruction with a local skin flap have a circular- or oval-shaped pattern. The majority of the skin flaps are planned in an angled shape. Therefore, it may be necessary to modify the shape of the defect or the distal flap border to minimize tissue distortion. We have designed a circular-shaped advancement flap to be compatible with the circular defect. METHODS: Eighteen cases of reconstruction of skin defects in the face, chest wall, hand and buttock area were performed using the omega advancement flap between 2010 and 2014...
December 30, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032573/a-new-lateral-thoracic-artery-perforator-flap-design-with-multiple-vascular-territories-in-rats
#16
Seçkin Aydın Savaş, Tahsin Gorgulu, Cumhur İbrahim Başsorgun, Arzu Akcal
BACKGROUND: To describe a new design for an extended lateral thoracic artery (LTA) perforator flap and investigate its anatomical, dynamic, and potential territories. MATERIALS AND METHODS: To assess vascular territories, rats were randomized according to LTA perforator flap type into the surgical groups A, hemidorsal island flap; B, entire dorsal island flap; and C, reduced-size dorsal island flap. RESULTS: On postsurgical day 7, the surviving flap areas were 95%, 92%, and 89% in groups A, B, and C, respectively...
August 26, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032165/an-alternative-posterosuperior-auricular-fascia-flap-for-ear-elevation-during-microtia-reconstruction
#17
Yiyuan Li, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li
BACKGROUND: Advances in staged total auricular reconstruction have resulted in improved anterior auricular appearance; however, satisfactory postreconstruction esthetics of the retroauricular fold remain challenging. The postauricular appearance of the reconstructed ear depends largely upon optimizing the covering material. When used as the covering soft tissue for ear elevation, a flap containing primarily the upper portion of the retroauricular fascia has potential advantages over the conventional book cover-type retroauricular fascia flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027237/experimental-rat-skin-flap-model-that-distinguishes-between-venous-congestion-and-arterial-ischemia-the-reverse-u-shaped-bipedicled-superficial-inferior-epigastric-artery-and-venous-system-flap
#18
Noriko M Matsumoto, Masayo Aoki, Junichi Nakao, Wei-Xia Peng, Yoshihiro Takami, Hiroki Umezawa, Satoshi Akaishi, Ryuji Ohashi, Zenya Naito, Rei Ogawa
BACKGROUND: The commonly used flap models have drawbacks that limit their usefulness. In the random skin flap model, flap necrosis is caused by both arterial and venous insufficiency. In the axial skin flap model, flap viability is easily affected by the pedicle blood flow and can result in complete necrosis. This study aimed to establish a new rat skin flap model that has a consistent flap survival rate and in which venous congestion and arterial ischemia can be readily distinguished macroscopically...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28027233/microporous-polysaccharide-hemospheres-potentiate-ischemia-induced-skin-flap-necrosis-in-a-murine-model
#19
Anaeze C Offodile, Bin Chen, Andrew S Aherrera, Lifei Guo
BACKGROUND: Microporous polysaccharide hemospheres are an increasingly used adjunctive measure for obtaining operative field hemostasis. However, the impact of these agents on survival of vascularly challenged tissues is unknown. The aim of this study was to investigate the effect, if any, of microporous hemospheres on tissue survival in a murine model. METHODS: Eighteen Sprague-Dawley rats underwent creation of two flanking dorsal, modified McFarlane-style flaps using a length-to-width ratio of 4:1...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28005787/nasopalatine-island-advancement-flap
#20
Amin Rahpeyma, Saeedeh Khajehahmadi
BACKGROUND: Anterior maxilla is a high esthetic region of the mouth. Some flaps are introduced for bone graft coverage, mainly based on secondary epithelization of connective tissue-periosteal tissues. This article evaluates the versatility of a new mucoperiosteal flap for reproducible coverage in anterior maxilla. METHODS: In 5 mongrel dogs a 5 mm width mucosal defect in labial mucosa was created after extraction of upper jaw incisors. Nasopalatine island advancement flap was used for mucosal replacement...
November 2016: Journal of Craniofacial Surgery
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