Kiera Ronda, Katelyn Downey, Amy Jenne, Monica Bastawrous, William W Wolff, Katrina Steiner, Daniel H Lysak, Peter M Costa, Myrna J Simpson, Karl J Jobst, Andre J Simpson
Environmental metabolomics provides insight into how anthropogenic activities have an impact on the health of an organism at the molecular level. Within this field, in vivo NMR stands out as a powerful tool for monitoring real-time changes in an organism's metabolome. Typically, these studies use 2D 13 C-1 H experiments on 13 C-enriched organisms. Daphnia are the most studied species, given their widespread use in toxicity testing. However, with COVID-19 and other geopolitical factors, the cost of isotope enrichment increased ~6-7 fold over the last two years, making 13 C-enriched cultures difficult to maintain...
June 20, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry