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https://www.readbyqxmd.com/read/29649975/characterising-resuscitation-promoting-factor-fluorescent-fusions-in-mycobacteria
#1
Iria Uhía, Nitya Krishnan, Brian D Robertson
BACKGROUND: Resuscitation promoting factor proteins (Rpfs) are peptidoglycan glycosidases capable of resuscitating dormant mycobacteria, and have been found to play a role in the pathogenesis of tuberculosis. However, the specific roles and localisation of each of the 5 Rpfs in Mycobacterium tuberculosis remain mostly unknown. In this work our aim was to construct fluorescent fusions of M. tuberculosis Rpf proteins as tools to investigate their function. RESULTS: We found that Rpf-fusions to the fluorescent protein mCherry are functional and able to promote cell growth under different conditions...
April 12, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29605787/basic-life-support-and-external-defibrillation-competences-after-instruction-and-at-6-months-comparing-face-to-face-and-blended-training-randomised-trial
#2
Jordi Castillo, Aberto Gallart, Encarnación Rodríguez, Jorge Castillo, Carmen Gomar
AIM OF THE STUDY: The objective of this study was to compare the immediate and 6-month efficacy of basic life support (BLS) and automatic external defibrillation (AED) training using standard or blended methods. METHODS: First-year students of medicine and nursing (n = 129) were randomly assigned to a control group (face-to-face training based on the European Resuscitation Council [ERC] Guidelines) or to an experimental group that trained with a self-training video, a new website, a Moodle platform, an intelligent manikin, and 45 min of instructor presence...
March 24, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29588994/-saved-by-the-bell-near-sudep-during-intracranial-eeg-monitoring
#3
Duaa M Ba-Armah, Elizabeth J Donner, Ayako Ochi, Cristina Go, Bláthnaid McCoy, Carter Snead, James Drake, Kevin C Jones
SUDEP is the sudden unexpected death of a person with epilepsy, when no structural or toxicological cause of death can be found. The majority of witnessed cases are reported to be preceded by a convulsive seizure and postictal hypoventilation. Here, we report an 8-year-old girl with drug-resistant focal seizures secondary to a focal cortical dysplasia type IIb. While undergoing invasive intracranial monitoring with subdural and depth electrodes, she had a clinical apnea event recorded on video, followed by bradycardia, which required resuscitation...
March 2018: Epilepsia open
https://www.readbyqxmd.com/read/29577094/value-of-continuous-video-eeg-and-eeg-responses-to-thermesthesia-stimulation-in-prognosis-evaluation-of-comatose-patients-after-cardiopulmonary-resuscitation
#4
Qiu Jianmin, You Xueliang, Liu Liqin, Wu Yongsheng, He Licang, Huang Yuanxin
Objective: To investigate the clinical value of video-electroencephalography (VEEG) and thermal stimulus on evaluating the prognosis of comatose patients after cardiopulmonary resuscitation. Methods: Twenty eight comatose patients with cardiopulmonary resuscitation were included in the department of ICU of the First Teaching Hospital of Fujian Medical University from February 2013 to March 2016. Of the included 28 patients, 20 cases died (death group) and 8 cases survived (survival group) after cardiopulmonary resuscitation...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29560076/pay-it-forward-high-school-video-based-instruction-can-disseminate-cpr-knowledge-in-priority-neighborhoods
#5
Marina Del Rios, Josiah Han, Alejandra Cano, Victor Ramirez, Gabriel Morales, Teri L Campbell, Terry Vanden Hoek
Introduction: The implementation of creative new strategies to increase layperson cardiopulmonary resuscitation (CPR) and defibrillation may improve resuscitation in priority populations. As more communities implement laws requiring CPR training in high schools, there is potential for a multiplier effect and reach into priority communities with low bystander-CPR rates. Methods: We investigated the feasibility, knowledge acquisition, and dissemination of a high school-centered, CPR video self-instruction program with a "pay-it-forward" component in a low-income, urban, predominantly Black neighborhood in Chicago, Illinois with historically low bystander-CPR rates...
March 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29553951/monitoring-peripheral-perfusion-and-microcirculation
#6
Arnaldo Dubin, Elizabeth Henriquez, Glenn Hernández
PURPOSE OF REVIEW: Microcirculatory alterations play a major role in the pathogenesis of shock. Monitoring tissue perfusion might be a relevant goal for shock resuscitation. The goal of this review was to revise the evidence supporting the monitoring of peripheral perfusion and microcirculation as goals of resuscitation. For this purpose, we mainly focused on skin perfusion and sublingual microcirculation. RECENT FINDINGS: Although there are controversies about the reproducibility of capillary refill time in monitoring peripheral perfusion, it is a sound physiological variable and suitable for the ICU settings...
March 15, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29504951/videographic-assessment-of-pediatric-tracheal-intubation-technique-during-emergency-airway-management
#7
Yuko Shiima, Ting-Chang Hsieh, Andrew Long, Aaron Donoghue
OBJECTIVES: To examine technical aspects of pediatric tracheal intubation using video recording and to determine the association between tracheal intubation technique and procedural outcomes. DESIGN: Prospective observational study. SETTING: Emergency department resuscitation bay in single tertiary pediatric center. PATIENTS: Children undergoing emergent tracheal intubation under videorecorded conditions. INTERVENTIONS: None...
March 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29491715/a-video-depicting-resuscitation-did-not-impact-upon-patients-decision-making
#8
Caitlin Richardson-Royer, Imran Naqvi, Christopher Riffel, Lawrence Harvey, Domonique Smith, Dagmawe Ayalew, Nasim Motayar, Yaw Amoateng-Adjepong, Constantine A Manthous
Background: Previous studies have demonstrated that video of and scripted information about cardiopulmonary resuscitation (CPR) can be deployed during clinician-patient end-of-life discussions. Few studies, however, examine whether video adds to verbal information-sharing. We hypothesized that video augments script-only decision-making. Methods: Patients aged >65 years admitted to hospital wards were randomized to receive evidence-based information ("script") vs...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29472255/comparison-of-a-newly-established-emotional-stimulus-approach-to-a-classical-assessment-driven-approach-in-bls-training-a-randomised-controlled-trial
#9
Karl Kuckuck, Hanna Schröder, Rolf Rossaint, Lina Stieger, Stefan K Beckers, Sasa Sopka
OBJECTIVE: The study objective was to implement two strategies (short emotional stimulus vs announced practical assessment) in the teaching of resuscitation skills in order to evaluate whether one led to superior outcomes. SETTING: This study is an educational intervention provided in one German academic university hospital. PARTICIPANTS: First-yearmedical students (n=271) during the first3 weeks of their studies. INTERVENTIONS: Participants were randomly assigned to one of two groups following a sequence of random numbers: the emotional stimulus group (EG) and the assessment group (AG)...
February 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29465279/a-continuous-quality-improvement-airway-program-results-in-sustained-increases-in-intubation-success
#10
David J Olvera, David F E Stuhlmiller, Allen Wolfe, Charles F Swearingen, Troy Pennington, Daniel P Davis
INTRODUCTION: Airway management is a critical skill for air medical providers, including the use of rapid sequence intubation (RSI) medications. Mediocre success rates and a high incidence of complications has challenged air medical providers to improve training and performance improvement efforts to improve clinical performance. OBJECTIVES: The aim of this research was to describe the experience with a novel, integrated advanced airway management program across a large air medical company and explore the impact of the program on improvement in RSI success...
February 21, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29451862/neonatal-resuscitation-experience-curves-simulation-based-mastery-learning-booster-sessions-and-skill-decay-patterns-among-pediatric-residents
#11
Heideh H Matterson, Demian Szyld, Brad R Green, Heather B Howell, Martin V Pusic, Pradeep V Mally, Sean M Bailey
BACKGROUND: Following neonatal resuscitation program (NRP) training, decay in clinical skills can occur. Simulation-based deliberate practice (SBDP) has been shown to maintain NRP skills to a variable extent. Our study objectives were (a) to determine whether a single 30 min simulation-based intervention that incorporates SBDP and mastery learning (ML) can effectively restore skills and prevent skill decay and (b) to compare different timing options. METHODS: Following NRP certification, pediatric residents were randomly assigned to receive a video-recorded baseline assessment plus SBDP-ML refresher education at between 6 and 9 months (early) or between 9 and 12 months (late)...
February 16, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29447297/development-of-a-decision-aid-for-cardiopulmonary-resuscitation-and-invasive-mechanical-ventilation-in-the-intensive-care-unit-employing-user-centered-design-and-a-wiki-platform-for-rapid-prototyping
#12
Ariane Plaisance, Holly O Witteman, Annie LeBlanc, Jennifer Kryworuchko, Daren Keith Heyland, Mark H Ebell, Louisa Blair, Diane Tapp, Audrey Dupuis, Carole-Anne Lavoie-Bérard, Carrie Anna McGinn, France Légaré, Patrick Michel Archambault
BACKGROUND: Upon admission to an intensive care unit (ICU), all patients should discuss their goals of care and express their wishes concerning life-sustaining interventions (e.g., cardiopulmonary resuscitation (CPR)). Without such discussions, interventions that prolong life at the cost of decreasing its quality may be used without appropriate guidance from patients. OBJECTIVES: To adapt an existing decision aid about CPR to create a wiki-based decision aid individually adapted to each patient's risk factors; and to document the use of a wiki platform for this purpose...
2018: PloS One
https://www.readbyqxmd.com/read/29437307/learning-cardiopulmonary-resuscitation-theory-with-face-to-face-versus-audiovisual-instruction-for-secondary-school-students-a-randomized-controlled-trial
#13
Cristina Cerezo Espinosa, Sergio Nieto Caballero, Laura Juguera Rodríguez, José Francisco Castejón-Mochón, Francisca Segura Melgarejo, Carmen María Sánchez Martínez, Carmen Amalia López López, Manuel Pardo Ríos
OBJECTIVES: To compare secondary students' learning of basic life support (BLS) theory and the use of an automatic external defibrillator (AED) through face-to-face classroom instruction versus educational video instruction. MATERIAL AND METHODS: A total of 2225 secondary students from 15 schools were randomly assigned to one of the following 5 instructional groups: 1) face-to-face instruction with no audiovisual support, 2) face-to-face instruction with audiovisual support, 3) audiovisual instruction without face-to-face instruction, 4) audiovisual instruction with face-to-face instruction, and 5) a control group that received no instruction...
February 2018: Emergencias: Revista de la Sociedad Española de Medicina de Emergencias
https://www.readbyqxmd.com/read/29432404/duration-to-establish-an-emergency-vascular-access-and-how-to-accelerate-it-a-simulation-based-study-performed-in-real-life-neonatal-resuscitation-rooms
#14
Eva M Schwindt, Florian Hoffmann, Philipp Deindl, Thomas J Waldhoer, Jens C Schwindt
OBJECTIVES: To compare the duration to establish an umbilical venous catheter and an intraosseous access in real hospital delivery rooms and as a secondary aim to assess delaying factors during establishment and to provide recommendations to accelerate vascular access in neonatal resuscitation. DESIGN: Retrospective analysis of audio-video recorded neonatal simulation training. SETTINGS: Simulation training events in exact replications of actual delivery/resuscitation rooms of 16 hospitals with different levels of care (Austria and Germany)...
February 9, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29401183/cognitive-aids-do-not-prompt-initiation-of-cardiopulmonary-resuscitation-in-simulated-pediatric-cardiopulmonary-arrests
#15
Kristen Nelson McMillan, Michael A Rosen, Nicole A Shilkofski, Jamie Haggerty Bradshaw, Mary Saliski, Elizabeth A Hunt
INTRODUCTION: Although American Heart Association guidelines exist for proper management of cardiopulmonary arrest (CPA), in-hospital cardiopulmonary resuscitation (CPR) may be of poor quality and is not performed in all indicated situations. Cognitive aids have been created to assist in rapid, accurate recall of guidelines for pediatric CPA management. METHODS: Pediatric residents participated in individual mock codes for two years. Using a high-fidelity simulator, each resident participated in a standardized scenario that required management of both pulseless ventricular tachycardia and pulseless electrical activity...
February 2018: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/29397897/tele-mentored-damage-control-and-emergency-trauma-surgery-a-feasibility-study-using-live-tissue-models
#16
Philip Dawe, Andrew Kirkpatrick, Max Talbot, Andrew Beckett, Naisan Garraway, Heather Wong, Syed Morad Hameed
BACKGROUND: Damage-control and emergency surgical procedures in trauma have the potential to save lives. They may occasionally not be performed due to clinician inexperience or lack of comfort and knowledge. METHODS: Canadian Armed Forces (CAF) non-surgeon Medical Officers (MOs) participated in a live tissue training exercise. They received tele-mentoring assistance using a secure video-conferencing application on a smartphone/tablet platform. Feasibility of tele-mentored surgery was studied by measuring their effectiveness at completing a set series of tasks in this pilot study...
February 2, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29391379/training-approaches-for-the-deployment-of-a-mechanical-chest-compression-device-a-randomised-controlled-manikin-study
#17
Keith Couper, Rochelle M Velho, Tom Quinn, Anne Devrell, Ranjit Lall, Barry Orriss, Joyce Yeung, Gavin D Perkins
OBJECTIVES: To evaluate the effect of training strategy on team deployment of a mechanical chest compression device. DESIGN: Randomised controlled manikin trial. SETTING: Large teaching hospital in the UK. PARTICIPANTS: Twenty teams, each comprising three clinicians. Participating individuals were health professionals with intermediate or advanced resuscitation training. INTERVENTIONS: Teams were randomised in a 1:1 ratio to receive either standard mechanical chest compression device training or pit-crew device training...
February 1, 2018: BMJ Open
https://www.readbyqxmd.com/read/29382690/man-in-his-50s-with-chest-pain-and-dyspnoea
#18
Yuki Obayashi, Chisato Izumi, Yoshihisa Nakagawa
CLINICAL INTRODUCTION: A man in his 50s with sudden-onset chest pain and dyspnoea was transferred to the emergency room. He had a history of aortic valve replacement due to aortic regurgitation with a mechanical valve 6 years previously. Heart rate was 90 bpm, and blood pressure was too low to measure. In the emergency room, he presented with severe dyspnoea and a chest X-ray showed severe lung congestion (figure 1A). ECG showed complete left bundle branch block. His respiratory status rapidly worsened, and he went into cardiopulmonary arrest...
January 30, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29366654/design-and-validation-of-a-tool-for-the-evaluation-of-the-quality-of-cardiopulmonary-resuscitation-sievca-cpr-2-0%C3%A2
#19
Segura Melgarejo Francisca, Pardo Ríos Manuel, Vera Catalán Tomás, Juguera Rodríguez Laura, Pérez Alonso Nuria, Leal Costa César, Martínez Riquelme Carolina, López Ayuso Belén
INTRODUCTION: Currently, no system completely evaluates the quality of cardio pulmonary resusciation. METHODS: A cross-sectional, prospective, longitudinal study using Delphi methodology was performed in three phases: preparatory, consultation and consensus. The validation was made by a prospective longitudinal study using the tool in the evaluation of 11 videos to determine the intra-class correlation coefficient (ICC) and the intra-subject (ICC-Initial), the latter repeated at four weeks (ICC-Final)...
January 20, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29364540/tactile-stimulation-during-neonatal-transition-and-its-effect-on-vital-parameters-in-neonates-during-neonatal-transition
#20
Nariae Baik-Schneditz, Berndt Urlesberger, Bernhard Schwaberger, Lukas Mileder, Georg Schmölzer, Alexander Avian, Gerhard Pichler
AIM: This study analysed tactile stimulation during neonatal transition and resuscitation in preterm and term neonates born by Caesarean delivery. It examined the frequency, location and body region, duration and possible effects of stimulation on heart rate and arterial oxygen saturation (SpO2 ). METHODS: Two independent investigators analysed video recordings of tactile stimulation on term and preterm neonates during neonatal transition from January 2012 to December 2014...
January 24, 2018: Acta Paediatrica
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