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Achilles tendon repair

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https://www.readbyqxmd.com/read/28891441/tissue-engineering-in-achilles-tendon-reconstruction-a-systematic-review-of-preclincal-studies
#1
Saqib Mir, Reza Mafi, Pouya Mafi, Wasim Khan
Background Tissue engineering is now being used in Achilles tendon (AT) repair in animal models. There are many preclinical studies that have used different types of stem cells for AT repair. However, there are no systematic reviews that evaluate all these studies to see which type of stem cell provides the most improvement for AT repair in animal models. Sahni V et al.,(1) divided the multiple stem cell types into three broad categories; Tendon derived stem cells (TDSCs), mesenchymal stem cells (MSCs) and embryonic stem cells (ESCs)...
September 6, 2017: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28891314/correlation-between-recovery-of-triceps-surae-muscle-strength-and-level-of-activity-after-open-repair-of-acute-achilles-tendon-rupture
#2
Seikai Toyooka, Hideki Takeda, Kohei Nakajima, Atsushi Masujima, Wataru Miyamoto, Gherardo Pagliazzi, Takumi Nakagawa, Hirotaka Kawano
BACKGROUND: This study aimed to determine whether physical findings reflecting triceps surae strength recovery could predict return to activities such as jogging and sports and whether patients' age and sex would influence recovery of triceps surae strength postoperatively. METHODS: Between 2009 and 2013, 96 consecutive cases of postoperative acute Achilles tendon rupture were reviewed. The postoperative triceps surae strength recovery rate was investigated in all patients by using half body weight 1-time heel rise, full body weight (FBW) 1-time heel rise, FBW 20-time heel rise, jogging, and full return to sports activities...
September 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28865587/surgical-repair-of-symptomatic-chronic-achilles-tendon-rupture-using-synthetic-graft-augmentation
#3
Ahmed Shoaib, Viren Mishra
BACKGROUND: Surgical repair of symptomatic chronic Achilles tendon (TA) rupture is a challenging problem due to the presence of a large defect between tendon edges. We report the results of surgical repair of symptomatic chronic TA rupture by synthetic graft augmentation. METHODS: Seven consecutive patients with a symptomatic chronic TA rupture underwent surgical repair by VY plasty and augmentation with bio-absorbable synthetic graft (Artelon(®)). In all patients, the intraoperative tendon gap after debridement was more than 5cm (Myerson Grade 3)...
September 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28857901/two-unique-cases-of-ciprofloxacin-associated-avulsion-of-ligament-and-tendon
#4
Jeffrey David Smith, Robert W Irwin, Erin T Wolff
Ciprofloxacin is recognized to have a deleterious relationship with tendons, particularly Achilles tendinopathy, which makes up most case reports. Tendinopathy seems to occur because of induction of collagen-degrading enzymes causing damage and ischemia of the poorly vascularized regions preventing repair. The focus on the relationship of ciprofloxacin and the Achilles tendon leaves patients on fluoroquinolones with non-Achilles tendinopathy symptoms at risk of misdiagnosis. There have not been any documented instances of ligament damage with ciprofloxacin administration in the literature, although ligament and tendon compositions are similar and should have similar susceptibility...
August 25, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28856168/functional-outcomes-of-achilles-tendon-minimally-invasive-repair-using-4-and-6-strand-nonabsorbable-suture-a-cohort-comparison-study
#5
Michael R Carmont, Jennifer A Zellers, Annelie Brorsson, Nicklas Olsson, Katarina Nilsson-Helander, Jon Karlsson, Karin Grävare Silbernagel
BACKGROUND: The aim of management of Achilles tendon rupture is to reduce tendon lengthening and maximize function while reducing the rerupture rate and minimizing other complications. PURPOSE: To determine changes in Achilles tendon resting angle (ATRA), heel-rise height, patient-reported outcomes, return to play, and occurrence of complications after minimally invasive repair of Achilles tendon ruptures using nonabsorbable sutures. STUDY DESIGN: Cohort study; Level of evidence, 3...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28842104/assessment-of-the-resistance-of-several-suture-techniques-in-human-cadaver-achilles-tendons
#6
Andrea Manent, Laia Lopez, Joan Vilanova, Tiago Mota, Jordi Alvarez, Alejandro Santamaría, Xavier Martí Oliva
Many treatments are available for acute Achilles tendon ruptures, conservative and surgical, with none superior to another. For surgical treatment, one can use various techniques. Recent studies have shown that double stitches are superior to simple sutures. Therefore, in the present study, we sought to determine the suture technique that is the most resistant to rupture. We performed an experimental anatomic study with 27 fresh-frozen human cadaveric Achilles tendons obtained through the body donation program of the University of Barcelona, testing the maximum strength...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28837456/temporal-healing-of-achilles-tendons-after-injury-in-rodents-depends-on-surgical-treatment-and-activity
#7
Benjamin R Freedman, Nabeel S Salka, Tyler R Morris, Pankti R Bhatt, Adam M Pardes, Joshua A Gordon, Courtney A Nuss, Corinne N Riggin, George W Fryhofer, Daniel C Farber, Louis Soslowsky
INTRODUCTION: Achilles tendon ruptures affect 15 of 100,000 women and 55 of 100,000 men each year. Controversy continues to exist regarding optimal treatment and rehabilitation protocols. The objective of this study was to investigate the temporal effects of surgical repair and immobilization or activity on Achilles tendon healing and limb function after complete transection in rodents. METHODS: Injured tendons were repaired (n = 64) or left nonrepaired (n = 64)...
September 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28806294/the-tissue-engineered-tendon-bone-interface-in-vitro-and-in-vivo-synergistic-effects-of-adipo-derived-stem-cells-platelet-rich-plasma-and-extracellular-matrix-hydrogel
#8
Rory McGoldrick, Arhana Chattopadhyay, Christopher Crowe, Grace Chiou, Kenneth Hui, Simon Farnebo, Christopher Davis, Anais Le Grand, Molly Jacobs, Hung Pham, James Chang
INTRODUCTION: Suboptimal healing of the tendon bone interface (TBI) remains an unsolved problem. One solution is a biocompatible tissue engineered construct that promotes augmented healing. We hypothesisze that 1.) the presence of Platelet Rich Plasma (PRP) and prolonged in vitro incubation produces tissue engineered tendon bone interface scaffolds with greater reseeding of viable Adipo-derived Stem Cells (ADSC) and 2.) when implanted with extracellular matrix hydrogel, constructs will display superior in vivo strength repair and biocompatibility...
August 3, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28800110/response-of-dermal-fibroblasts-to-biochemical-and-physical-cues-in-aligned-polycaprolactone-silk-fibroin-nanofiber-scaffolds-for-application-in-tendon-tissue-engineering
#9
Chih-Hao Chen, Shih-Hsien Chen, Chang-Yi Kuo, Meng-Lun Li, Jyh-Ping Chen
Silk fibroin (SF) and fiber alignment were introduced into polycaprolactone (PCL)-based electrospun nanofibers as chemical and physical cues for tendon tissue engineering applications. The physicochemical properties of random PCL (RP) nanofibers, random PCL/SF (RPSF) nanofibers and aligned PCL/SF (APSF) nanofibers were characterized for fiber orientation and SF blending effects. An in vitro cell culture with rabbit dermal fibroblasts (RDFBs) on nanofibers indicated that SF promotes cell proliferation to a higher extent than fiber alignment...
August 11, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28759732/therapeutic-effects-of-doxycycline-on-the-quality-of-repaired-and-unrepaired-achilles-tendons
#10
Quynhhoa T Nguyen, Jolanta B Norelli, Adam Graver, Charles Ekstein, Johnathan Schwartz, Farzana Chowdhury, Mark C Drakos, Daniel A Grande, Nadeen O Chahine
BACKGROUND: Achilles tendon tears are devastating injuries, especially to athletes. Elevated matrix metalloproteinase (MMP) activity after a tendon injury has been associated with deterioration of the collagen network and can be inhibited with doxycycline (Doxy). HYPOTHESIS: Daily oral administration of Doxy will enhance the histological, molecular, and biomechanical quality of transected Achilles tendons. Additionally, suture repair will further enhance the quality of repaired tendons...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28750046/wnt-%C3%AE-catenin-signaling-suppresses-expressions-of-scx-mkx-and-tnmd-in-tendon-derived-cells
#11
Yasuzumi Kishimoto, Bisei Ohkawara, Tadahiro Sakai, Mikako Ito, Akio Masuda, Naoki Ishiguro, Chisa Shukunami, Denitsa Docheva, Kinji Ohno
After tendon injuries, biomechanical properties of the injured tendon are not fully recovered in most cases. Modulation of signaling pathways, which are involved in tendon development and tendon repair, is one of attractive modalities to facilitate proper regeneration of the injured tendon. The roles of TGF-β signaling in tendon homeostasis and tendon development have been elucidated. In contrast, the roles of Wnt/β-catenin signaling in tendon remain mostly elusive. We found that the number of β-catenin-positive cells was increased at the injured site, suggesting involvement of Wnt/β-catenin signaling in tendon healing...
2017: PloS One
https://www.readbyqxmd.com/read/28742993/performance-and-return-to-sport-after-achilles-tendon-repair-in-national-football-league-players
#12
Robert A Jack, Kyle R Sochacki, Stephanie S Gardner, Patrick C McCulloch, David M Lintner, Pedro E Cosculluela, Kevin E Varner, Joshua D Harris
BACKGROUND: Achilles tendon injuries are common in sports, including football. The purpose of this study was to determine (1) return-to-sport rate in National Football League (NFL) players following Achilles tendon repair, (2) postoperative career length and games per season, (3) pre- and postoperative performance, and (4) postoperative performance compared with control players matched by position, age, years of experience, and performance. METHODS: Publicly available records were used to identify NFL players who underwent Achilles tendon repair and matched controls were identified...
July 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28737307/absorbable-polydioxanone-pds-suture-provides-fewer-wound-complications-than-polyester-ethibond-suture-in-acute-tendo-achilles-rupture-repair
#13
M N Baig, I Yousaf, J G Galbraith, R Din
We prospectively studied acute Achilles tendon rupture in patients over a two 2-year period and reviewed the causes, outcome and complications. There were 53 patients included with acute Achilles rupture with minimum follow up period of 6 months. We compared the outcomes including infection rate and Boyden score between the two groups repaired by Polydioxanone and Polyester respectively. All infected cases had a suture repair using the polyester suture. The difference in the infection rate was highly significant between the 2 groups (p=0...
May 10, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/28733950/tendon-end-separation-with-loading-in-an-achilles-tendon-repair-model-comparison-of-non-absorbable-vs-absorbable-sutures
#14
Michael R Carmont, Jan Herman Kuiper, Karin Grävare Silbernagel, Jón Karlsson, Katarina Nilsson-Helander
BACKGROUND: Rupture of the Achilles tendon often leads to long-term morbidity, particularly calf weakness associated with tendon elongation. Operative repair of Achilles tendon ruptures leads to reduced tendon elongation. Tendon lengthening is a key problem in the restoration of function following Achilles tendon rupture. A study was performed to determine differences in initial separation, strength and failure characteristics of differing sutures and numbers of core strands in a percutaneous Achilles tendon repair model in response to initial loading...
December 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28717614/activity-level-recovery-after-acute-achilles-tendon-rupture-surgically-repaired-a-series-of-29-patients-with-a-mean-follow-up-of-46-months
#15
Richard Zayni, Raphaël Coursier, Moudasser Zakaria, Jean-François Desrousseaux, Denis Cordonnier, Gilles Polveche
BACKGROUND: Achilles tendon rupture is a common injury but its optimal management is still controversial. When decided, surgical repair can be performed by open or percutaneous techniques. Till now, there is no agreement on the ideal type of surgical management. PURPOSE: To compare the outcomes of the percutaneous and open surgical treatment for acute Achilles tendon rupture and to assess the postoperative activity level recovery. METHODS: Between 2008 and 2013, 29 patients were surgically treated for acute Achilles tendon rupture in our institution...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717611/conservative-minimally-invasive-and-open-surgical-repair-for-management-of-acute-ruptures-of-the-achilles-tendon-a-clinical-and-functional-retrospective-study
#16
Gayle Maffulli, Angelo Del Buono, Paula Richards, Francesco Oliva, Nicola Maffulli
BACKGROUND: At present, it is unclear which is the best management for Achilles tendon rupture. PURPOSE: We assess the clinical, functional and imaging outcomes of active patients undergoing 3 different types of management for acute subcutaneous rupture of the Achilles tendon, including conservative cast immobilization, traditional open surgery and percutaneous repair. METHODS: 26 active patients were managed for a rupture of the Achilles Tendon from January 2007 to March 2008...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28690460/analysis-of-player-statistics-in-major-league-baseball-players-before-and-after-achilles-tendon-repair
#17
Bryan M Saltzman, Matthew W Tetreault, Daniel D Bohl, Danielle Tetreault, Simon Lee, Bernard R Bach
BACKGROUND: No currently available literature evaluates the effect of Achilles tendon repair on professional baseball players in the Major League Baseball (MLB). QUESTIONS/PURPOSES: The purpose of this study was to determine the impact of Achilles tendon rupture and repair on MLB players in terms of return to play and batting/fielding performance metrics. METHODS: Achilles tendon rupture data were retrospectively collected using information from the MLB disabled list, injury reports, MLB game summaries, player profiles, and publicly available news articles...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28668970/achilles-tendon-rupture-healing-is-enhanced-by-intermittent-pneumatic-compression-upregulating-collagen-type-i-synthesis
#18
Md Abdul Alim, Erica Domeij-Arverud, Gunnar Nilsson, Gunnar Edman, Paul W Ackermann
PURPOSE AND HYPOTHESIS: Adjuvant intermittent pneumatic compression (IPC) during leg immobilization following Achilles tendon rupture (ATR) has been shown to reduce the risk of deep venous thrombosis. The purpose of this study was to investigate whether IPC can also promote tendon healing. METHODS: One hundred and fifty patients with surgical repair of acute ATR were post-operatively leg immobilized and prospectively randomized. Patients were allocated for 2 weeks of either adjuvant IPC treatment (n = 74) or treatment-as-usual (n = 74) in a plaster cast without IPC...
July 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28660438/lower-material-stiffness-in-rupture-repaired-achilles-tendon-during-walking-transmission-mode-ultrasound-for-post-surgical-tendon-evaluation
#19
Mathias Wulf, Mihir Shanker, Michael Schuetz, Michael Lutz, Christian M Langton, Sue L Hooper, James E Smeathers, Torsten Brauner, Scott C Wearing
PURPOSE: This cross-sectional study used transmission-mode ultrasound to evaluate dynamic tendon properties during walking in surgically repaired and contralateral Achilles tendon (AT), with a median (range) post-operative period of 22 (4-58) months. It was hypothesised that the axial transmission speed of ultrasound (TSOU) during walking would be slower, indicating lower material stiffness in repaired compared with contralateral AT. METHODS: Ten patients [median (range) age 47 (37-69) years; height 180 (170-189) cm; weight 93 (62-119) kg], who had undergone open surgical repair of the AT and were clinically recovered according to their treating clinicians, walked barefoot on a treadmill at self-selected speed (1...
June 28, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28655680/open-wounds-of-the-achilles-tendon-in-tropical-settings-36%C3%A2-cases-at-the-donka-university-hospital-in-guinea-conakry
#20
L Lamah, M Diallo, J B D Tékpa, M L Bah, K Keita, S Sidime, M T Soumah, I Diallo
The aim of this study was to analyze the epidemiologic, etiologic, and therapeutic aspects of open wounds of the Achilles tendon managed in the Donka University Hospital. This 3-year prospective included all patients admitted for an Achilles tendon injury. Closed injuries, suppurating wounds, and those that occurred more than 24 hours before admission were excluded. Surgical treatment consisted in debridement and tendon repair, with plaster cast protection for 6 weeks. The study included 36 patients with a mean age of 23...
June 1, 2017: Médecine et Santé Tropicales
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