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https://www.readbyqxmd.com/read/29746144/effects-of-allogenic-dermal-fibroblasts-on-rotator-cuff-healing-in-a-rabbit-model-of-chronic-tear
#1
Jieun Kwon, Yun Hee Kim, Sung-Min Rhee, Tae In Kim, Jimin Lee, Saewha Jeon, Joo Han Oh
BACKGROUND: The failure of rotator cuffs to heal after repair is an unresolved surgical issue. There have been substantial efforts, including the use of biological supplements, to enhance tendon healing. Dermal fibroblasts are a good candidate for tendon tissue engineering because they are similar to the tenocytes used for collagen synthesis. In addition, they are easily accessible because autologous dermal fibroblasts can be obtained from individual skin without major skin defects and allogenic dermal fibroblasts (ADFs) have already been commercialized in the field of skin engineering...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29727650/mechanical-structural-and-physical-aspects-of-chitosan-based-films-as-antimicrobial-dressings
#2
Ana A Escárcega-Galaz, Dalia I Sánchez-Machado, Jaime López-Cervantes, Ana Sanches-Silva, Tomás J Madera-Santana, Perfecto Paseiro-Losada
Chitosan is a biodegradable, non-toxic, and antimicrobial polymer. Chitosan films can be used as a dressing because they promote the healing of cutaneous ulcers. In this study, the mechanical, physical, and microbiological properties films of pure chitosan and films formulated with a glycerol-honey mixture were characterized. The films were smooth, homogenous, transparent, and porous, with no fractures or cracks. Additionally, it was found that all were resistant to breaking, that the tearing force was directly related to the chitosan concentration, and that the addition of honey and glycerol improved the elongation percentage...
May 1, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29726315/the-risk-of-skin-tear-in-dupuytren-s-disease-when-treated-with-collagenase
#3
Christian Fagernæs, Susanne Mallet
INTRODUCTION: The purpose of this study was to explore if there was a correlation between joint level and degree of contracture on the one hand and the risk of skin tear in Dupuytren's disease (DD) on the other, when treated with collagenase from Clostridium histolyticum. No trial or study has explored the risk of skin tear as primary outcome in a population that has not been treated for DD before. METHODS: A retrospective study of prospectively collected data was performed on patients with DD treated with collagenase from 1 August 2012 to 1 April 2014...
May 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29718815/prevalence-of-skin-tears-in-elderly-patients-a-retrospective-chart-review-of-incidence-reports-in-6-long-term-care-facilities
#4
Joyce Hawk, Mary Shannon
The incidence and prevalence of skin tears in long-term care (LTC) facilities has not been well established. To ascertain the point prevalence of reported skin tears, a retrospective review of incident reports was performed in 6 LTC facilities in western Pennsylvania from November 1, 2016 through December 31, 2016. Report data, including resident age; gender; mobility limitations; skin tear location, number, and cause (if known); occurrence time (7 am to 3 pm, 3 pm to 11 pm, or 11 pm to 7 am nursing shift); and history of previous skin tears, were abstracted...
April 2018: Ostomy/wound Management
https://www.readbyqxmd.com/read/29688838/intense-pulsed-light-applied-directly-on-eyelids-combined-with-meibomian-gland-expression-to-treat-meibomian-gland-dysfunction
#5
Bei Rong, Yun Tang, Ping Tu, Ruixing Liu, Jing Qiao, Wenjing Song, Rolando Toyos, Xiaoming Yan
OBJECTIVE: To determine the efficacy and safety of intense pulsed light (IPL) applied directly on the eyelids and meibomian gland expression (MGX) in treating meibomian gland dysfunction (MGD). BACKGROUND: IPL application on the periocular skin effectively improves meibomian gland secretion and tear film break-up time (TBUT) in patients with MGD/dry eye. METHODS: This prospective, randomized, double-masked, controlled study involved 44 patients...
April 24, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29649416/improving-mechanical-properties-of-molded-silicone-rubber-for-soft-robotics-through-fabric-compositing
#6
Yue Wang, Cherry Gregory, Mark A Minor
Molded silicone rubbers are common in manufacturing of soft robotic parts, but they are often prone to tears, punctures, and tensile failures when strained. In this article, we present a fabric compositing method for improving the mechanical properties of soft robotic parts by creating a fabric/rubber composite that increases the strength and durability of the molded rubber. Comprehensive ASTM material tests evaluating the strength, tear resistance, and puncture resistance are conducted on multiple composites embedded with different fabrics, including polyester, nylon, silk, cotton, rayon, and several blended fabrics...
March 19, 2018: Soft Robotics
https://www.readbyqxmd.com/read/29621374/novel-use-of-a-volumizing-hyaluronic-acid-filler-for-treatment-of-infraorbital-hollows
#7
Michael B Hall, Sudeep Roy, Edward D Buckingham
Importance: Hyaluronic acid filler can be safely used as a soft-tissue filler for correction of infraorbital hollowing. It has a high overall patient satisfaction profile among patients. Objective: To report safety and patient satisfaction outcomes of Juvéderm Voluma XC for correction of infraorbital hollows. Design, Setting, and Patients: This was a retrospective observational study performed at a private ambulatory facial plastic and reconstructive surgery practice...
April 5, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29608475/percutaneous-autologous-fat-injection-following-2-layer-flap-lower-blepharoplasty-for-the-correction-of-tear-trough-deformity
#8
Jeenam Kim, Hyojeong Shin, Myungchul Lee, Donghyeok Shin, Soonheum Kim, Dongin Jo, Cheolkeun Kim, Heonjoon Kim, Hyungon Choi
Tear trough deformity has been an area that has received much attention in terms of esthetic improvements. Fat transposition has been commonly used for the treatment of tear trough deformity. As some patients have had minimal improvement by that method, we propose the use of fat grafting combined with open blepharoplasty to complement the sunken area, including some of anterior maxilla region, and evaluate and precisely remove the excessive tissue.Lower blepharoplasty was performed by separating the skin and muscle flap...
March 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29578686/silicones-for-stretchable-and-durable-soft-devices-beyond-sylgard-184
#9
Sungjune Park, Kunal Mondal, Robert M Treadway, Vikash Kumar, Siyuan Ma, James D Holbery, Michael D Dickey
This paper identifies and characterizes silicone elastomers that are well-suited for fabricating highly stretchable and tear-resistant devices that require interfacial bonding by plasma or UV ozone treatment. The ability to bond two or more pieces of molded silicone is important for creating microfluidic channels, chambers for pneumatically driven soft robotics, and other soft and stretchable devices. Sylgard-184 is a popular silicone, particularly for microfluidic applications. However, its low elongation at break (∼100% strain) and moderate tear strength (∼3 N/mm) make it unsuitable for emerging, mechanically demanding applications of silicone...
March 26, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29569862/recognising-and-managing-age-related-dermatoporosis-and-skin-tears
#10
Valentina Vanzi, Elena Toma
Dermatoporosis is a chronic skin fragility syndrome, caused by age and environmental factors. People with dermatoporosis have skin whose protective mechanical function is reduced and which has a decreased tolerance for friction and shearing forces. Skin tears are another clinical consequence of age-associated skin vulnerability and people with dermatoporosis are at increased risk of skin tears. Dermatoporosis may also delay the healing of skin tears, making it vital that healthcare professionals are aware of this condition...
March 23, 2018: Nursing Older People
https://www.readbyqxmd.com/read/29560057/baby-shampoo-to-relieve-the-discomfort-of-tear-gas-and-pepper-spray-exposure-a-randomized-controlled-trial
#11
Jason P Stopyra, James E Winslow, James C Johnson, Keith D Hill, William P Bozeman
Introduction: Oleoresin capsicum (OC) or pepper spray, and tear gas (CS) are used by police and the military and produce severe discomfort. Some have proposed that washing with baby shampoo helps reduce this discomfort. Methods: We conducted a prospective, randomized, controlled study to determine if baby shampoo is effective in reducing the severity and duration of these effects. Study subjects included volunteers undergoing OC or CS exposure as part of their police or military training...
March 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29556679/-infections-after-reconstructive-spinal-interventions-how-do-i-deal-with-them
#12
REVIEW
Burkhard Lehner, Michael Akbar, Nicholas A Beckmann
BASICS: Postoperative surgical site infections of the spine have been described in up to 20% of patients and can result in serious consequences for the patient and substantial treatment costs. Typical bacteria often arise from skin or fecal flora. Various risk factors for infection have been described, including obesity, diabetes, high ASA scores, as well as intraoperative factors such as heavy blood loss, dural tears, or several revision procedures. Consequently, the prophylaxis with pre- and postoperative risk minimization is of particular importance...
March 20, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29528586/validity-of-specific-immunoglobulin-e-assay-in-tear-film-for-detection-of-allergens-inducing-different-types-of-allergic-conjunctivitis
#13
Randa S Abdel-Latif, Nissreen E ELBadawy, Basem M Ibrahim
This is a prospective interventional comparative study which aimed to investigate correlation between tear film allergen specific IgE levels and the skin prick test in diagnosing different types of allergic conjunctivitis. One hundred twenty patients with allergic conjunctivitis were included in this study and were classified into 4 groups based on the type of allergic conjunctivitis. Patients were subjected to skin prick test (SPT). Micro capillary method was used to collect tear samples for the quantitative assessment of specific IgE by Immune blot assay...
June 2017: Egyptian Journal of Immunology
https://www.readbyqxmd.com/read/29464916/prevalence-of-skin-tears-in-the-extremities-in-inpatients-at-a-hospital-in-denmark
#14
Susan Bermark, Britt Wahlers, Anne Liv Gerber, Peter Alshede Philipsen, Jette Skiveren
The aims of the study were to determine the prevalence of skin tears in the extremities and to explore factors associated with development of skin tears in inpatients at a Danish hospital. The study was designed as a point prevalence survey and included 202 patients in the age range 19-99 (mean: 70·7, SD: 16·5). The patients were assessed for presence of skin tears, numbers, locations and previous skin tears. Data were collected using a data collection sheet developed for a previous study. The survey team consisted of four specialist nurses...
April 2018: International Wound Journal
https://www.readbyqxmd.com/read/29464374/heterogeneous-pattern-of-autonomic-dysfunction-in-parkinson-s-disease
#15
Laurène Leclair-Visonneau, Laurent Magy, Christelle Volteau, Thomas Clairembault, Séverine Le Dily, Cécile Préterre, Arnaud Peyre, Philippe Damier, Michel Neunlist, Yann Péréon, Pascal Derkinderen
Dysautonomic symptoms are frequent non-motor complaints in patients with Parkinson's disease. Numerous neuropathological studies have shown that Lewy bodies and neurites, the pathological hallmarks of Parkinson's disease, are widely distributed throughout the peripheral autonomic nervous systems and across end organs. However, few investigations integrally explored the symptoms and physiology of dysautonomia in Parkinson's disease. We, therefore, performed a comprehensive evaluation of the autonomic function in a prospective group of 45 patients with idiopathic Parkinson's disease...
April 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29463801/compensatory-increases-in-tear-volume-and-mucin-levels-associated-with-meibomian-gland-dysfunction-caused-by-stearoyl-coa-desaturase-1-deficiency
#16
Takaaki Inaba, Yasuhisa Tanaka, Shusaku Tamaki, Tomotaka Ito, James M Ntambi, Kazuo Tsubota
The stearoyl-CoA desaturase (SCD) family of enzymes catalyzes monounsaturated fatty acid synthesis by inserting a cis double bond at the Δ9 position of saturated fatty acids. Disruption of these enzymes has been reported to induce a severe dry skin phenotype. Since lipid abnormalities in the meibomian glands have been associated with dry eye, we analyzed selected eye tissues contributing to tear volume and composition in genetically SCD-1-deficient mice (SCD-1 KO), including the lacrimal glands and conjunctiva...
February 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29424026/tough-and-water-insensitive-self-healing-elastomer-for-robust-electronic-skin
#17
Jiheong Kang, Donghee Son, Ging-Ji Nathan Wang, Yuxin Liu, Jeffrey Lopez, Yeongin Kim, Jin Young Oh, Toru Katsumata, Jaewan Mun, Yeongjun Lee, Lihua Jin, Jeffrey B-H Tok, Zhenan Bao
An electronic (e-) skin is expected to experience significant wear and tear over time. Therefore, self-healing stretchable materials that are simultaneously soft and with high fracture energy, that is high tolerance of damage or small cracks without propagating, are essential requirements for the realization of robust e-skin. However, previously reported elastomers and especially self-healing polymers are mostly viscoelastic and lack high mechanical toughness. Here, a new class of polymeric material crosslinked through rationally designed multistrength hydrogen bonding interactions is reported...
March 2018: Advanced Materials
https://www.readbyqxmd.com/read/29422859/successful-subcutaneous-allergen-specific-immunotherapy-in-refractory-atopic-keratoconjunctivitis-a-case-report
#18
Passara Jongkhajornpong, Wannada Laisuan
Purpose: We report a case of refractory atopic keratoconjunctivitis (AKC) which was successfully treated with subcutaneous immunotherapy (SCIT). Case Report: A 22-year-old woman presented with severe allergic conjunctivitis for one and a half year. She failed to respond to conventional topical anti-allergic medications, topical corticosteroid, as well as topical cyclosporine A. Therefore, oral corticosteroids had to be prescribed to control the exacerbation for 1 year...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29420232/better-outcome-from-arthroscopic-partial-meniscectomy-than-skin-incisions-only-a-sham-controlled-randomised-trial-in-patients-aged-35-55-years-with-knee-pain-and-an-mri-verified-meniscal-tear
#19
Ewa M Roos, Kristoffer Borbjerg Hare, Sabrina Mai Nielsen, Robin Christensen, L Stefan Lohmander
OBJECTIVE: Compare arthroscopic partial meniscectomy to a true sham intervention. METHODS: Sham-controlled superiority trial performed in three county hospitals in Denmark comparing arthroscopic partial meniscectomy to skin incisions only in patients aged 35-55 years with persistent knee pain and an MRI-confirmed medial meniscus lesion. A computer-generated table of random numbers generated two comparison groups. Participants and outcome assessors were blinded to group allocation...
February 2, 2018: BMJ Open
https://www.readbyqxmd.com/read/29399465/endoscopic-all-inside-repair-of-the-flexor-hallucis-longus-tendon-in-posterior-ankle-impingement-patients
#20
Akinobu Nishimura, Shigeto Nakazora, Naoya Ito, Aki Fukuda, Ko Kato, Akihiro Sudo
Longitudinal flexor hallucis longus (FHL) tendon tears are sometimes complicated by posterior ankle impingement syndrome (PAIS), especially in ballet dancers. In recent years, PAIS has been treated endoscopically, but it is difficult to suture FHL tendon tears endoscopically. In this report, we describe how to suture the FHL tendon endoscopically with the Meniscal Viper Repair system (Arthrex, Naples, FL). Without our endoscopic technique, when a patient is found to have a longitudinal tear of the FHL under endoscopy, we must choose to either neglect the tear or convert to an open repair...
October 2017: Arthroscopy Techniques
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