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https://www.readbyqxmd.com/read/29325546/development-and-evaluation-of-a-measure-of-patient-reported-symptoms-of-blepharitis
#1
Kamran Hosseini, Linda B Bourque, Ron D Hays
BACKGROUND: Blepharitis is an ocular surface disease and chronic ophthalmic condition. This paper reports on the development of psychometric evaluation of a patient-reported measure of blepharitis symptoms. METHODS: Self-reports of 13 blepharitis symptoms collected in a Phase 3 multi-site, randomized, double-masked, 4-arm parallel group, clinical trial of 907 individuals with blepharitis (mean age = 62, range: 19-93; 57% female) were analyzed. Symptoms asked about were: eyes that itch; eyes that burn; eyelids feel heavy or puffy; feel like something is in your eye; dry eyes; gritty eyes; irritated eyes; eyes that tear or water; crusty eyes; flaking from your eyelids; eyelids that are stuck together; red eyes or eyelids; and debris like pieces of skin or dandruff in your eyes...
January 11, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29306579/first-aid-for-skin-tears-by-mini-patch-grafting-from-the-flap-edge
#2
Isamu Ikeda, Toshikatsu Igata, Hironobu Ihn
BACKGROUND: Traumatic skin tears often occur in patients with dystrophic skin. Closing them with adhesive skin closures is useful for patients with a healthy flap, but occasionally fails to cover the entire defect. We describe a simple technique to perform mini patch grafting on the remaining raw surface without damaging healthy skin. DISCUSSION: The skin flap is spread out and fixed with adhesive skin strips to minimize defects first. Small pieces of skin are obtained by trimming the edges of the skin flap with curved tip scissors...
January 3, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29288543/artificially-modified-collagen-fibril-orientation-affects-leather-tear-strength
#3
Susyn J Kelly, Hannah C Wells, Katie H Sizeland, Nigel Kirby, Richard L Edmonds, Tim Ryan, Adrian Hawley, Stephen Mudie, Richard G Haverkamp
BACKGROUND: Ovine leather has around half the tear strength of bovine leather and is therefore not suitable for high value applications such as shoes. Tear strength has been correlated with the natural collagen fibril alignment (orientation index, OI). It is hypothesized that it could be possible to artificially increase the OI of the collagen fibrils and that an artificial increase in OI could increase tear strength. RESULTS: Ovine skins, after the pickling and bating, were strained bi-axially during chrome tanning...
December 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29205275/antenatal-maternal-education-for-improving-postnatal-perineal-healing-for-women-who-have-birthed-in-a-hospital-setting
#4
REVIEW
Sonia M O'Kelly, Zena Eh Moore
BACKGROUND: The female perineum becomes suffused and stretched during pregnancy, and further strain during vaginal childbirth contributes to approximately 85% of women experiencing some degree of trauma to the perineal region. Multiple factors play a role in the type and severity of trauma experienced, including parity, delivery method, and local practices. There is ongoing debate about best midwifery practice to reduce perineal trauma. Once perineal trauma has occurred, treatment also varies greatly, depending on its degree and severity, local practice and customs, and personal preference...
December 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29202765/a-novel-technique-for-modified-all-inside-repair-of-bucket-handle-meniscus-tears-using-standard-arthroscopic-portals
#5
Jing Hui Yik, Bryan Thean Howe Koh, Wilson Wang
BACKGROUND: Bucket-handle meniscus tears (BHMT) are often displaced and unstable. The inside-out technique of repairing such tears is currently the gold standard. All-inside repair with meniscal fixators is getting increasingly popular. Shortcomings of the inside-out technique include neurovascular complications, especially saphenous nerve palsy, and retention of a non-resorbable suture which can result in discomfort to patient, granuloma formation, and a foci of infection. Hence, the purpose of this project was to innovate a novel all-inside technique to precisely reduce and fix BHMT while avoiding neurovascular complications and retention of a non-resorbable suture...
December 4, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29164949/local-pro-inflammatory-cytokine-and-nitric-oxide-responses-are-elevated-in-patients-with-pterygium
#6
S Zidi, F Bediar-Boulaneb, H Belguendouz, M Belkhelfa, O Medjeber, O Laouar, C Henchiri, C Touil-Boukoffa
Pterygium is a common ocular surface disease observed in humans. Chronic ultraviolet (UV) exposure is extensively recognized as an aetiological factor in the pathogenesis of this disease. This hypothesis is sustained by epidemiological and histopathological data in relation to UV injured skin. Although some findings have indicated that genetic factors, anti-apoptotic and immunological mechanisms are involved in the pathogenesis of pterygium, the mechanism by which it develops remains poorly understood. In this study, we analysed the in vivo production of IL-17A, IL-6, IL-10 and nitric oxide (NO) in the tears and sera from Algerian patients...
November 1, 2017: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/29132305/associations-between-skin-barrier-characteristics-skin-conditions-and-health-of-aged-nursing-home-residents-a-multi-center-prevalence-and-correlational-study
#7
Elisabeth Hahnel, Ulrike Blume-Peytavi, Carina Trojahn, Jan Kottner
BACKGROUND: Geriatric patients are affected by a range of skin conditions and dermatological diseases, functional limitations and chronic diseases. Skin problems are highly prevalent in elderly populations. Aim of this study was to investigate possible associations between health, functional and cutaneous variables in aged long-term care residents. METHODS: This observational, cross-sectional, descriptive prevalence study was conducted in a random sample of 10 institutional long-term care facilities in Berlin...
November 13, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29128285/prolonged-and-localized-sweat-stimulation-by-iontophoretic-delivery-of-the-slowly-metabolized-cholinergic-agent-carbachol
#8
Phillip Simmers, S Kevin Li, Gerald Kasting, Jason Heikenfeld
BACKGROUND: Continuous non-invasive sampling and sensing of multiple classes of analytes could revolutionize medical diagnostics and wearable technologies, but also remains highly elusive because of the many confounding factors for candidate biofluids such as interstitial fluid, tears, saliva, and sweat. Eccrine sweat biosensing has seen a recent surge in demonstrations of wearable sampling and sensing devices. However, for subjects at rest, access to eccrine sweat is highly limited and unpredictable compared to saliva and tears...
November 8, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29117825/acute-compartment-syndrome-of-upper-extremities-with-tendon-ruptures
#9
Taku Suzuki, Eiko Yamabe, Takuji Iwamoto, Katsuji Suzuki, Harumoto Yamada, Kazuki Sato
BACKGROUND: It is well known that acute compartment syndrome is associated with fracture of the forearm, while involvement of soft tissue injury including musculotendinous injury remains unclear. The purpose of this study was to evaluate the soft tissue involvement, including musculotendinous ruptures, in acute compartment syndrome of the upper limb. METHODS: We retrospectively enrolled 16 patients who underwent surgical treatment for acute compartment syndrome of the upper extremity...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29077953/the-comet-assay-applied-to-cells-of-the-eye
#10
Amaya Azqueta, Elisa Rundén-Pran, Elisabeth Elje, Bjørn Nicolaissen, Kristiane Haug Berg, Ingrida Smeringaiova, Katerina Jirsova, Andrew R Collins
The human eye is relatively unexplored as a source of cells for investigating DNA damage. There have been some clinical studies, using cells from surgically removed tissues, and altered DNA bases as well as strand breaks have been measured using the comet assay. Tissues examined include corneal epithelium and endothelium, lens capsule, iris and retinal pigment epithelium. For the purpose of biomonitoring for exposure to potential mutagens in the environment, the eye-relatively unprotected as it is compared with the skin-would be a valuable object for study; non-invasive techniques exist to collect lachrymal duct cells from tears, or cells from the ocular surface by impression cytology, and these methods should be further developed and validated...
October 25, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29075507/pilot-parallel-randomised-controlled-trial-of-protective-socks-against-usual-care-to-reduce-skin-tears-in-high-risk-people-stopcuts
#11
Roy J Powell, Christopher J Hayward, Caroline L Snelgrove, Kathleen Polverino, Linda Park, Rohan Chauhan, Philip H Evans, Rachel Byford, Carolyn Charman, Christopher J W Foy, Colin Pritchard, Andrew Kingsley
BACKGROUND: Skin tears are common in older adults and those taking steroids and warfarin. They are traumatic, often blunt injuries caused by oblique knocks to the extremities. The epidermis may separate from the dermis or both layers from underlying tissues leaving a skin flap or total loss of tissue, which is painful and prone to infection. 'Dermatuff™' knee-length socks containing Kevlar fibres (used in stab-proof vests and motorcyclists' clothing) aim to prevent skin tears. The acceptability of the socks and the feasibility of a randomised controlled trial (RCT) had not been explored...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29066268/do-skin-lacerations-imply-tissue-transfer-from-surgeon-to-patient-during-arthroscopic-knot-tying
#12
Matthew B Burn, Heidi L Holtorf, Kevin M Smith, Derek T Bernstein, Domenica A Delgado, Nickarr Prudhomme, Michael T Deavers, Patrick C McCulloch, Joshua D Harris
PURPOSE: To use simulated arthroscopic knot tying to assess (1) whether epithelial cells from the surgeon's hands were transmitted to the suture and (2) whether the number of knots tied or the presence of glove tears would correlate with the number of cells transmitted. METHODS: Knots were tied in a simulated arthroscopic environment using a nonabsorbable No. 2 suture over a metal hook. The surgeon was double gloved for each knot tied. For each "anchor," a surgeon's knot was tied, followed by 3 reversed half-hitches on alternating posts...
October 21, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29052530/health-impacts-of-chemical-irritants-used-for-crowd-control-a-systematic-review-of-the-injuries-and-deaths-caused-by-tear-gas-and-pepper-spray
#13
Rohini J Haar, Vincent Iacopino, Nikhil Ranadive, Sheri D Weiser, Madhavi Dandu
BACKGROUND: Chemical irritants used in crowd control, such as tear gases and pepper sprays, are generally considered to be safe and to cause only transient pain and lacrimation. However, there are numerous reports that use and misuse of these chemicals may cause serious injuries. We aimed to review documented injuries from chemical irritants to better understand the morbidity and mortality associated with these weapons. METHODS: We conducted a systematic review using PRISMA guidelines to identify injuries, permanent disabilities, and deaths from chemical irritants worldwide between January 1, 1990 and March 15, 2015...
October 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29045078/skin-tears-and-risk-factors-assessment-a-systematic-review-on-evidence-based-medicine
#14
Raffaele Serra, Nicola Ielapi, Andrea Barbetta, Stefano de Franciscis
Skin tears represent a common condition of traumatic wounds, which may be encountered in some categories of individuals at the extremes of age, such as infants and the elderly. Despite the high prevalence and cost of these lesions, there has been little investigation into the risk factors that lead to this condition. The aim of this review was to systematically evaluate the main risk factors involved in development of skin tears. We planned to include all the studies dealing with risk factors related to skin tears...
October 17, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29023238/severe-phenotype-of-keratitis-ichthyosis-deafness-syndrome-with-presumed-ocular-surface-squamous-neoplasia
#15
Ana Silvia Serrano-Ahumada, Vianney Cortes-González, Luz María González-Huerta, Sergio Cuevas, Luis Aguilar-Lozano, Cristina Villanueva-Mendoza
PURPOSE: The aim of this study was to describe a case of severe keratitis-ichthyosis-deafness (KID) syndrome with ocular surface squamous neoplasia. METHODS: The affected patient underwent complete ocular and systemic examinations. The molecular studies included polymerase chain reaction amplification and automated DNA sequencing of the complete gap junction beta-2 (GJB2) gene coding sequence. RESULTS: A 30-year-old man presented with generalized erythro-hyperkeratosis and deafness and complaints of decreased visual acuity, tearing, and photophobia...
October 10, 2017: Cornea
https://www.readbyqxmd.com/read/28970200/wearable-physiological-systems-and-technologies-for-metabolic-monitoring
#16
Wei Gao, George A Brooks, David C Klonoff
Wearable sensors allow continuous monitoring of metabolites for diabetes, sports medicine, exercise science, and physiology research. These sensors can continuously detect target analytes in skin interstitial fluid (ISF), tears, saliva, and sweat. In this review, we will summarize developments on wearable devices and their potential applications in research, clinical practice, and recreational and sporting activities. Sampling skin ISF can require insertion of a needle into the skin, whereas sweat, tears, and saliva can be sampled by devices worn outside the body...
September 28, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28960820/minimally-invasive-transforaminal-lumbar-interbody-fusion-and-unilateral-fixation-for-degenerative-lumbar-disease
#17
Hui-Wang Wang, Yong-Cheng Hu, Zhan-Yong Wu, Hua-Rong Wu, Chun-Fu Wu, Lian-Suo Zhang, Wei-Kun Xu, Hui-Long Fan, Jin-Sheng Cai, Jian-Qing Ma
OBJECTIVE: To evaluate the clinical effect of the minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation using a tubular retractor in the management of degenerative lumbar disease. METHODS: A retrospective analysis was conducted to analyze the clinical outcome of 58 degenerative lumbar disease patients who were treated with minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation during December 2012 to January 2015...
August 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28940714/tear-drop-free-anterolateral-thigh-flap-a-versatile-design-for-lower-limb-reconstruction-after-trauma
#18
Sergio Razzano, Sami Ramadan, Andrea Figus, Richard M Haywood
BACKGROUND: In lower limb reconstruction the cosmetic outcome is influenced by the contouring of the flap at the recipient site as well as by the donor site closure. It is also important to minimise compression of the flap pedicle. We discuss the outcomes of a versatile ALT flap design that allows freedom in skin paddle tailoring without elongating the scar, reduction of the tension over the pedicle and improved cosmetic results of both donor and recipient sites. METHODS: Between January 2009 and October 2015, 27 patients underwent reconstruction using tear drop ALTs...
September 21, 2017: Microsurgery
https://www.readbyqxmd.com/read/28939333/variants-of-latissimus-dorsi-with-a-perspective-on-tendon-transfer-surgery-an-anatomic-study
#19
Anu V Ranade, Rajalakshmi Rai, Ashwin R Rai, Prameela M Dass, Mangala M Pai, Rajanigandha Vadgaonkar
BACKGROUND: The latissimus dorsi (LD) is often used for tendon transfers to treat massive irreparable posterosuperior rotator cuff tears. The operation requires the LD tendon to be mobilized to reduce tension on the tendon. In that respect, any connection between the LD tendon and contiguous muscles may hamper tendon mobility and affect the surgical outcome. The goal of this study was to document the occurrence of connections between the LD and adjacent muscles and nerves. METHODS: We studied the scapular region on 48 embalmed cadavers...
September 19, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28917432/complications-after-treating-dupuytren-s-disease-a-systematic-literature-review
#20
C Krefter, M Marks, S Hensler, D B Herren, M Calcagni
The objective of this study was to review the incidence of complications associated with different treatment options for patients with Dupuytren's disease. In a systematic literature review, the PubMed, EMBASE, Cochrane and Scopus databases were searched for clinical studies reporting complications after collagenase treatment, percutaneous needle fasciotomy (PNF), fasciectomy and dermofasciectomy. The incidence of complications was extracted from each study and stratified by procedure. From a total of 2251 references, 113 studies were analyzed and included with complication incidences varying from 0% to 100%...
October 2017: Hand Surgery and Rehabilitation
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