keyword
https://read.qxmd.com/read/38619860/exploring-clinical-variability-in-gelsolin-amyloidosis-brazilian-family-case-study-with-confocal-microscopy
#1
JOURNAL ARTICLE
Caio Brenno Abreu, Bárbara Flores Culau Merlo, Vinícius da Silva Varandas, Juliana de Sá Freire Medrado Dias
INTRODUCTION: Genetic mutations or inflammatory, degenerative, or neoplastic conditions can trigger amyloidosis. Hereditary gelsolin amyloidosis is a genetic disorder primarily marked by amyloid fibrils composed of misfolded gelsolin fragments. CASE REPORT: We present three sisters with AGel amyloidosis, illustrating its clinical diversity. Patient 1, a 51-year-old, had bilateral ptosis, ocular discomfort, and dry eye syndrome due to cranial nerve involvement. Patient 2, a 53-year-old, experienced progressive bilateral visual impairment...
April 15, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38607365/skin-conductance-algesimeter-is-unreliable-during-sudden-perioperative-temperature-increases
#2
JOURNAL ARTICLE
Ulf E Kongsgaard, Robin Johansen Menchini, Stein Gunnar Larsen, Knut Erling Juul-Hansen
OBJECTIVES: Pain assessment in anesthetized and non-communicative patients remains a challenge. Clinical signs such as tachycardia, hypertension, sweat and tears, have a low specificity for pain and should therefore ideally be replaced by more specific monitoring techniques. Skin conductance variability has been demonstrated to establish a patients' sensitivity to pain, but may be influenced by temperature changes that leads to profuse sweating. The aim of this pilot study was to test skin conductance changes during sudden temperature changes due to hyperthermic intraperitoneal chemotherapy (HIPEC) perfusation...
January 1, 2024: Scandinavian Journal of Pain
https://read.qxmd.com/read/38594154/impact-of-thermo-mechanical-skin-treatment-on-refraction-and-keratometry-in-patients-with-dry-eye-disease-and-the-implications-for-cataract-surgery
#3
JOURNAL ARTICLE
Marta Blanco-Vázquez, Raquel Gil-Cazorla, Ankur Barua, Mukesh Taneja, Ludger Hanneken, Sunil Shah
PURPOSE: To determine the changes in keratometry measurements and refraction in patients having the thermo-mechanical periorbital skin treatment, Tixel®, to treat dry eye disease (DED). METHODS: A multi-centre, prospective, non-masked study was conducted. DED patients were recruited in 3 international centres and were evaluated in 5 visits separated by an interval of 2 weeks except for the last visit which took place after 18 weeks from visit 1. The same clinical examination was performed at all visits: OSDI questionnaire, tear stability, keratometry, best corrected visual acuity and refraction...
April 8, 2024: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://read.qxmd.com/read/38553803/in-vitro-biomechanical-properties-of-porcine-perineal-tissues-to-better-understand-human-perineal-tears-during-delivery
#4
JOURNAL ARTICLE
Marine Lallemant, Tiguida Kadiakhe, Jerôme Chambert, Arnaud Lejeune, Rajeev Ramanah, Nicolas Mottet, Emmanuelle Jacquet
INTRODUCTION: Data concerning the mechanical properties of the perineum during delivery are very limited. In vivo experiments raise ethical issues. The aim of the study was to describe some of the biomechanical properties of each perineal tissue layer collected from sows in order to better understand perineal tears during childbirth. MATERIAL AND METHODS: Samples of each perineal tissue layer were obtained from the skin, the vagina, the external anal sphincter (EAS), the internal anal sphincter (IAS), and the anal mucosa of fresh dead sows...
March 29, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38548611/-transoral-robotic-thyroidectomy-via-vestibular-approach-a-retrospective-study-of-107-cases-in-a-single-center
#5
JOURNAL ARTICLE
X L Li, S J Chen, C Y Li, X J Cao, D Y Zhuang, P Zhou, T Yue, M Wang, J Zhu, Q Q He
Objective: To investigate the short-term outcome of transoral robotic thyroidectomy. Methods: This is a retrospective case series study. The clinicopathologic characteristics and postoperative results of 107 patients who underwent transoral robotic thyroidectomies in the Department of Thyroid and Breast Surgery of the 960th Hospital of People's Liberation Army from May 2020 to August 2023 were retrospectively analyzed. There were 12 males and 95 females, with an age of (31.8±9.4) years (range: 11 to 55 years), including 20 benign tumors and 87 thyroid papillary carcinoma...
March 27, 2024: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://read.qxmd.com/read/38545776/clinical-efficacy-and-safety-of-composite-non-cross-linked-hyaluronic-acid-for-treating-tear-trough-lower-eyelid-bag-deformity
#6
JOURNAL ARTICLE
Xiaomei Zhou, Yan Yi, Zeming Liu, Qi Zhang, Yiping Wu, Xiao Luo
BACKGROUND: Tear trough-eye bag deformities may appear in young Asian patients due to the weak support of their facial skeletons. For these patients with better periorbital skin elasticity, the injection may be more suitable than surgery for treating tear trough-lower eyelid bag deformity. AIMS: Identify the clinical efficacy and safety of non-cross-linked HA in the treatment of tear trough-lower eyelid bag deformity. METHODS: In this study, we analyzed pre- and postinjection photographs of 55 patients treated with non-cross-linked hyaluronic acid (HA) for tear trough-lower eyelid bag deformity...
March 28, 2024: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38543356/press-conduction-welding-for-secondary-bonding-of-aircraft-skin-stiffener-assemblies-using-carbon-fiber-pekk-thermoplastic-composites-and-pei-adhesive
#7
JOURNAL ARTICLE
Hyunseok Choi, Chan-Joo Lee, Yong-Jun Jeon, Woo-Chun Choi, Dongearn Kim
This study investigates the secondary bonding of aircraft skin/stiffener assemblies using press conduction welding with carbon fiber/polyetherketoneketone thermoplastic composites and polyetherimide adhesive. Recognizing the challenges posed by conventional welding methods in maintaining material integrity and uniformity, this research explores an alternative methodology that mitigates these issues while ensuring high-strength bonds. The press conduction welding parameters were selected based on single-lap shear tests and applied in the bonding of skin and omega stiffener components...
March 9, 2024: Polymers
https://read.qxmd.com/read/38539332/non-suicidal-self-injury-nssi-patterns-in-adolescents-from-a-romanian-child-psychiatry-inpatient-clinic
#8
JOURNAL ARTICLE
Lucia Emanuela Andrei, Magdalena Efrim-Budisteanu, Ilinca Mihailescu, Alexandra Mariana Buică, Mihaela Moise, Florina Rad
Non-Suicidal Self-Injury (NSSI) involves deliberately causing harm to one's body without the intention of suicide. As the numbers of adolescents presenting NSSI have been steadily increasing during the last years, we intended to investigate adolescent patients exhibiting NSSI, admitted to our clinic-a Romanian child psychiatry inpatient clinic, over the course of five years. A total of 100 adolescents (80 females, 20 males, mean age: 14.9 years) hospitalized for various neuropsychiatric disorders and engaging in self-harm were studied...
March 1, 2024: Children
https://read.qxmd.com/read/38537039/effect-of-upper-eyelid-blepharoplasty-on-the-ocular-surface-tear-film-and-corneal-microstructure
#9
JOURNAL ARTICLE
Orhan Aygun, Yonca Ozkan Arat, Ozlem Dikmetas, Jale Karakaya, Ata Baytaroglu, Murat Irkec
PURPOSE: This study aimed to investigate the effect of upper eyelid blepharoplasty with the removal of the skin and a strip of orbicularis oculi muscle on the ocular surface, tear film, and dry eye-related symptoms. METHODS: Twenty-two eyes of 22 consecutive patients operated by a single surgeon (21 females; mean age, 61 years; age range, 41-75 years) were included. All subjects completed the Ocular Surface Disease Index questionnaire, underwent in vivo confocal microscopy, tear film breakup time measurements, the Schirmer test with anesthesia, and fluorescein and lissamine green staining measurements before, 1 month, and 6 months after upper blepharoplasty alone with preseptal orbicularis excision...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38517552/biomechanical-analysis-of-the-human-derived-soft-tissue-graft-epiflex-for-use-in-oral-soft-tissue-augmentation
#10
JOURNAL ARTICLE
Keyvan Sagheb, Robert Noelken, Saskia-Vanessa Schröger, Christian Walter, Julian Jakob Graef, Sven Schumann
PURPOSE: This study aimed to investigate the biomechanical properties, cell migration, and revascularization of the acellular dermal matrix Epiflex. As a decellularized, freeze-dried human skin graft, Epiflex has broad applications in medical fields, particularly in implantology and dentistry. Understanding its biomechanical characteristics is crucial for its clinical adoption as a novel soft tissue graft option. METHODS: Epiflex (n = 3) was evaluated in comparison to palatal tissue from body donors (n = 3)...
March 22, 2024: International Journal of Implant Dentistry
https://read.qxmd.com/read/38515557/treatment-of-cicatricial-lower-eyelid-ectropion-with-suture-of-horner-muscle-combined-with-fascia-transplantation
#11
JOURNAL ARTICLE
Kento Takaya, Shigeki Sakai, Kazuo Kishi
This case series aimed to describe a new technique for correcting contractures and deformities that reliably addresses lacrimal punctum deviation and severe cicatricial lower eyelid ectropion. This was a technical description and a retrospective interventional case series. Eyelid ectropion and lacrimal punctum deviation were treated surgically by grafting the fascia lata and suturing the tarsus-Horner muscle. In total, three patients underwent this surgery: one for burns, one for lower eyelid tumor resection, and the other for an orbital floor fracture following a motorcycle accident, all resulting in ectropion...
March 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38506890/risk-of-infections-related-to-endovascular-catheters-and-cardiac-implantable-devices-in-hemodialysis-patients
#12
REVIEW
Gaetano Alfano, Niccolò Morisi, Silvia Giovanella, Monica Frisina, Alessio Amurri, Lorenzo Tei, Maria Ferri, Giulia Ligabue, Gabriele Donati
Patients requiring dialysis are extremely vulnerable to infectious diseases. The high burden of comorbidities and weakened immune system due to uremia and previous immunosuppressive therapy expose the patient on dialysis to more infectious events than the general population. The infectious risk is further increased by the presence of endovascular catheters and implantable cardiologic devices. The former is generally placed as urgent vascular access for dialysis and in subjects requiring hemodialysis treatments without autogenous arteriovenous fistula...
March 20, 2024: Journal of Vascular Access
https://read.qxmd.com/read/38505682/effects-of-a-leave-on-product-on-the-strength-of-the-dermoepidermal-junction-an-exploratory-intraindividual-randomized-controlled-trial-in-older-adults-with-dry-skin
#13
JOURNAL ARTICLE
Ruhul Amin, Fiorenza Rancan, Kathrin Hillmann, Ulrike Blume-Peytavi, Annika Vogt, Jan Kottner
BACKGROUND AND AIMS: Skin aging is associated with dry skin and a decrease of the strength of the dermoepidermal adhesion, which increases the risk for lacerations (skin tears). Application of leave-on products improves dry skin and seems to reduce skin tear incidence. The aim of this study was to measure the effects of a humectant containing leave-on product on the strength of the dermoepidermal junction in older adult participants with dry skin. METHODS: A randomized controlled trial using a split body design was conducted...
March 2024: Health Science Reports
https://read.qxmd.com/read/38490501/biceps-rerouting-augmentation-technique-restores-biomechanics-improves-healing-and-has-many-advantages-for-repair-of-large-and-massive-rotator-cuff-tears
#14
EDITORIAL
Yang-Soo Kim, Sung-Hyun Cho
The biceps rerouting (BR) augmentation technique has emerged as a useful option for the repair of rotator cuff tears (RCTs) when the torn tendon does not cover the footprint or can only be reduced under excessive tension. BR offers several advantages over traditional methods. It is an all-inside joint procedure, eliminating the need for skin incisions other than those for the arthroscopic portal, thus reducing operative time and infection risk. It does not lead to donor site morbidity, (unlike superior capsular reconstruction...
March 13, 2024: Arthroscopy
https://read.qxmd.com/read/38489829/lower-eyelid-dark-circles-tear-trough-and-lid-cheek-junction-a-stepwise-assessment-framework
#15
JOURNAL ARTICLE
Steven Liew, Simone Doreian, Wachira Kunathathorn, Stephanie Lam, Alvin Jorge, Lam Bee Lan, Ellen Selkon, Sean Arendse, Jodie Silleri, Tara Telfer
BACKGROUND: Despite increasing popularity, the use of hyaluronic acid (HA) fillers for the correction of dark under eye shadows remains challenging. Specific guidance on patient assessment is limited. OBJECTIVES: To develop a stepwise assessment framework for lower eyelid dark shadows to help practitioners to classify patients based on their underlying problems and facilitate a more strategic approach to treatment. METHODS: Literature review and peer collaboration informed the current availability of educational material for use by experienced injectors when assessing patients presenting with dark circles...
March 15, 2024: Aesthetic Surgery Journal
https://read.qxmd.com/read/38478422/nursing-care-in-patients-with-dependency-related-skin-injuries-in-the-community-a-scoping-review
#16
JOURNAL ARTICLE
Natalia Maella-Rius, Joan-Enric Torra-Bou, Laura Martínez-Rodríguez
PURPOSE: Dependency-related skin injuries (DRSI) occur in people who need a high level of support to carry out day-to-day activities. Owing to the ageing population, the number of people at risk of DRSI is increasing. Most wound care is performed by nurses in the community. This scoping review aimed to identify the extent of literature on nursing care for patients with or at risk of developing DRSI living in their own home. MATERIALS AND METHODS: A scoping review was conducted...
March 1, 2024: British Journal of Community Nursing
https://read.qxmd.com/read/38468689/amnion-derived-hydrogels-as-a-versatile-platform-for-regenerative-therapy-from-lab-to-market
#17
REVIEW
Golara Kafili, Hassan Niknejad, Elnaz Tamjid, Abdolreza Simchi
In recent years, the amnion (AM) has emerged as a versatile tool for stimulating tissue regeneration and has been of immense interest for clinical applications. AM is an abundant and cost-effective tissue source that does not face strict ethical issues for biomedical applications. The outstanding biological attributes of AM, including side-dependent angiogenesis, low immunogenicity, anti-inflammatory, anti-fibrotic, and antibacterial properties facilitate its usage for tissue engineering and regenerative medicine...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38443083/risk-factors-for-medical-adhesive-related-skin-injury-at-the-site-of-peripherally-inserted-central-venous-catheter-placement-in-patients-with-cancer-a-single-centre-prospective-study-from-china
#18
JOURNAL ARTICLE
Mengying Qi, Yuju Qin, Siya Meng, Nan Feng, Yan Meng
OBJECTIVES: This study aims to explore the incidence of, and risk factors for medical adhesive-related skin injury (MARSI) at peripherally inserted central venous catheter (PICC) sites in patients with cancer. DESIGN: A prospective observational cohort study was conducted at a tertiary hospital in Shenzhen, China. SETTING: This was a single-centre study conducted in a tertiary hospital in Shenzhen, China. PARTICIPANTS: A total of 340 patients with cancer and PICC placement from January 2022 to June 2023 were selected using a convenience sampling method...
March 4, 2024: BMJ Open
https://read.qxmd.com/read/38442507/insights-and-mechanics-driven-modeling-of-human-cutaneous-impact-injuries
#19
JOURNAL ARTICLE
Omar Elsafty, Christopher A Berkey, Reinhold H Dauskardt
Cutaneous damage mechanisms related to dynamic fragment impacts are dependent on the impact angle, impact energy, and fragment characteristics including shape, volume, contact friction, and orientation. Understanding the cutaneous injury mechanism and its relationship to the fragment parameters is lacking compromising damage classification, treatment, and protection. Here we develop a high-fidelity dynamic mechanics-driven model for partial-thickness skin injuries and demonstrate the influence of fragment parameters on the injury mechanism and damage sequence...
February 13, 2024: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/38435245/meniscus-side-knot-tying-technique-instead-of-capsular-side-knot-tying-in-arthroscopic-outside-in-meniscal-repair-a-small-but-meaningful-modification
#20
JOURNAL ARTICLE
Ashraf Abdelkafy
Arthroscopic outside-in meniscal repair technique, which was first described by Warren in 1985, including all its later modifications, involved tying the final knot on the outer surface of the capsule. Capsular-side knot-tying has reported complications such as catching sensory nerves under the knot with resultant postoperative focal sensory loss and paresthesia, as well as pain under the skin because of irritation from the knot. Meniscus-side-knot-tying technique involves tying the knot on the outer surface of the meniscus...
February 2024: Arthroscopy Techniques
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