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Peroral endoscopic myotomy

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https://www.readbyqxmd.com/read/29156013/a-novel-strategy-to-initiate-a-peroral-endoscopic-myotomy-program
#1
J Matthew Reinersman, Dennis A Wigle, Christopher J Gostout, Louis M Wong Kee Song, Shanda H Blackmon
OBJECTIVES: The standard of care for achalasia remains laparoscopic Heller myotomy with partial fundoplication. Peroral endoscopic myotomy (POEM) has been introduced as an alternative, but safety and long-term comparative efficacy are not yet established. We report our experience in developing a POEM program using a novel hybrid approach. METHODS: We developed a hybrid approach to POEM with a POEM followed by laparoscopic evaluation, extension of the myotomy, if necessary, and partial fundoplication...
October 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29134329/esophageal-motility-disorders-new-perspectives-from-high-resolution-manometry-and-histopathology
#2
REVIEW
Hiroki Sato, Kazuya Takahashi, Ken-Ichi Mizuno, Satoru Hashimoto, Junji Yokoyama, Go Hasegawa, Shuji Terai
High-resolution manometry (HRM) and peroral endoscopic myotomy (POEM) have contributed significantly to the field of esophageal motility disorders in recent years. The development of HRM has categorized various esophageal motility disorders with a focus on a diverse range of manometric anomalies. Additionally, the Chicago classification criteria is widely used for manometric diagnosis. Moreover, POEM was introduced as a minimally invasive radical therapy for achalasia and shows promise for other spastic esophageal motility disorders as well...
November 13, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29113005/is-integrated-relaxation-pressure-a-promising-predictor-of%C3%A2-effectiveness-of-peroral-endoscopic-myotomy-for-achalasia
#3
Hong Jin, Wei Zhao, Lili Zhang, Zhongqing Zheng, Tao Wang, Lanlan Wu, Bangmao Wang
Background Peroral endoscopic myotomy (POEM), first introduced in 2010, appears to be an effective therapy with few complications. This study aimed to find an optimal predictor of POEM outcome in achalasia. Methods We retrospectively assessed 89 patients diagnosed with achalasia who underwent POEM in General Hospital of Tianjin Medical University, from September 2012 to March 2015. Associations of Eckardt score with symptom duration, lower esophageal resting pressure, 4-second integrated relaxation pressure (4s-IRP), and maximum esophageal diameter were assessed before POEM...
November 7, 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29073699/severe-submucosal-fibrosis-the-achilles-heel-of-peroral-endoscopic-myotomy
#4
Zaheer Nabi, D Nageshwar Reddy, Mohan Ramchandani
No abstract text is available yet for this article.
November 2017: Endoscopy
https://www.readbyqxmd.com/read/29046961/modified-peroral-endoscopic-myotomy-a-push-and-pull-technique
#5
Dan-Feng Zhang, Wei-Feng Chen, Mei-Dong Xu, Yun-Shi Zhong, Yi-Qun Zhang, Quan-Lin Li, Ping-Hong Zhou
BACKGROUND: Peroral endoscopic myotomy (POEM) is a minimally invasive yet challenging procedure for achalasia. Additional technological innovations and improvements are important for simplifying the procedure. METHODS: We report the successful use of a modified POEM procedure, which utilized a "Push and Pull" technique, on a patient with achalasia. RESULTS: Our modifications resulted in a short operation time of only 35 min. No complications arose during or after the procedure, up to a follow-up period of 6 months, and symptoms were significantly and quickly improved...
October 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29046776/the-safety-of-endoscopic-esophageal-procedures-under-general-anesthesia
#6
Go Eun Kim, Duk Kyung Kim, Ji Won Choi, In Sun Chung, Da Woon Jung
BACKGROUND: With the increasing demand for general anesthesia for endoscopic esophageal procedures, anesthesiologists should understand the clinical characteristics of post-procedural complications (PPCs). METHODS: We retrospectively investigated the incidence of and risk factors associated with PPCs of endoscopic esophageal procedures performed under general anesthesia from July 2013 to November 2016. The final analysis included 129 patients; 114 who underwent esophageal endoscopic dissection for esophageal tumors and 15 cases of peroral endoscopic myotomy for achalasia...
October 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29030799/gastric-peroral-endoscopic-pyloromyotomy-therapy-for-refractory-gastroparesis
#7
REVIEW
Petros C Benias, Mouen A Khashab
Purpose of review Gastroparesis is a complex dysmotility disorder in which a number of normal gastric emptying mechanisms can be affected. The pylorus as an apparatus is particularly important since it stands as the last final gateway for gastric emptying. As such, pyloric interventions seem to be successful in reducing symptoms and also improving emptying of solids, an effect not observed with other medical interventions. Recent findings Gastric peroral endoscopic myotomy (G-POEM) is a novel technique which offers the promise of mimicking the success of a traditional surgical pyloroplasty, while embracing the minimally invasive paradigm of flexible endoscopic surgery...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28992639/open-peroral-endoscopic-myotomy-for-achalasia-with-sigmoid-shaped-esophagus
#8
Wei Liu, Ling Liu, Hong-Lin Chen, Hong-Ze Zeng, Chun-Cheng Wu, Lian-Song Ye, Bing Hu
No abstract text is available yet for this article.
October 9, 2017: Endoscopy
https://www.readbyqxmd.com/read/28983652/what-the-radiologist-needs-to-know-about-gastrointestinal-endoscopic-surgical-procedures
#9
REVIEW
Chandana Lall, Anastasia A Cruz, Vlad Bura, Adam A Rudd, Thangavijayan Bosemani, Kenneth J Chang
Natural orifice transluminal endoscopic surgery (NOTES) is a novel surgical approach, currently performed for an array of conditions. Endoscopic procedures offer significant benefits, including lower cost, no surgical incisions, and shorter hospital stays. These advantages align with the current trends in health care, namely a push for "cost-effective care." There are a multitude of health issues which are now being addressed by the endoscopic surgical approach, including peroral endoscopic myotomy (POEM), which is a relatively new technique used in the treatment of achalasia...
October 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28919276/-focus-on-achalasia
#10
Marie-Anne Guillaumot, Maximilien Barret, Sarah Leblanc, Mahaut Leconte, Bertrand Dousset, Ammar Oudjit, Frédéric Prat, Stanislas Chaussade
The pathophysiology of achalasia is largely unknown, and involves the destruction of ganglion cell in the esophageal myenteric plexus. High-resolution esophageal manometry is the key investigation. Endoscopic pneumodilatation and laparoscopic Heller myotomy have comparable short-term success rates, around 90%. The main complication after pneumodilatation is esophageal perforation, occurring in about 1% of cases. Peroral endoscopic myotomy is a promising treatment modality, however with frequent post-procedural gastroesophageal reflux...
September 14, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28916889/teaching-peroral-endoscopic-myotomy-poem-to-surgeons-in-practice-an-into-the-fire-pre-post-test-curriculum
#11
Tomokazu Kishiki, Brittany Lapin, Chi Wang, Brandon Jonson, Lava Patel, Matthew Zapf, Matthew Gitelis, Maria A Cassera, Lee L Swanström, Michael B Ujiki
INTRODUCTION: With the increasing adoption of peroral endoscopic myotomy (POEM) as a first-line therapy for achalasia as well as a growing list of other indications, it is apparent that there is a need for effective training methods for both endoscopists in training and those already in practice. We present a hands-on-focused with pre- and post-testing methodology to teach these skills. METHODS: Six POEM courses were taught by 11 experienced POEM endoscopists at two independent simulation laboratories...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28898921/long-term-quality-of-life-after-peroral-endoscopic-myotomy-remains-compromised-in-patients-with-achalasia-type-iii
#12
Oscar V Hernández Mondragón, Marina A González Martinez, Juan M Blancas Valencia, Maria L Hernandez Reyes, Omar M Solórzano Pineda, Gerardo Blanco Velasco
Background and study aims Peroral endoscopic myotomy (POEM) is an excellent endoscopic treatment for achalasia. Clinical and manometric parameters are used for evaluation and follow-up. However, clinical success does not guarantee high quality of life (QoL) scores, generating doubts about their direct relationship. We aimed to evaluate QoL scores before and after POEM at medium and long term, to evaluate differences between achalasia subtypes and find which factors related to low QoL scores. Patients and methods Achalasia-confirmed patients undergoing POEM between February 2012 and November 2016...
September 12, 2017: Endoscopy
https://www.readbyqxmd.com/read/28867972/peroral-endoscopic-myotomy-for-the-management-of-esophageal-disorders
#13
Ian S Grimm
No abstract text is available yet for this article.
July 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28867969/an-overview-of-achalasia-and-its-subtypes
#14
Dhyanesh A Patel, Brian M Lappas, Michael F Vaezi
Achalasia is one of the most studied esophageal motility disorders. However, the pathophysiology and reasons that patients develop achalasia are still unclear. Patients often present with dysphagia to solids and liquids, regurgitation, and varying degrees of weight loss. There is significant latency prior to diagnosis, which can have nutritional implications. The diagnosis is suspected based on clinical history and confirmed by esophageal high-resolution manometry testing. Esophagogastroduodenoscopy is necessary to rule out potential malignancy that can mimic achalasia...
July 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28859393/open-peroral-endoscopic-myotomy-o-poem-for-the-treatment-of-achalasia
#15
W Liu, H-Z Zeng, H-L Chen, C-C Wu, L-S Ye, B Hu
With the development of endoscopic interventions and inspired by the success of peroral endoscopic myotomy (POEM) for the treatment of achalasia, we investigated an old method of direct peroral endoscopic myotomy without a submucosal tunnel for the treatment of achalasia, which we call open peroral endoscopic myotomy (O-POEM). In this study, Clinical success was achieved in the patient after O-POEM. A reduction of LES pressure, Eckardt score, and a timed barium esophagogram were observed during follow-up. There were no severe complications and no recurrences during two months of follow-up...
October 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28845589/gastrointestinal-peroral-endoscopic-myotomy-for-distal-esophageal-spasm
#16
X Tang, Y Ren, S Huang, X Zhang, W Gong
No abstract text is available yet for this article.
September 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28827050/initial-experience-with-peroral-endoscopic-myotomy-for-treatment-of-achalasia-in-children
#17
William C Kethman, Chad M Thorson, Tiffany J Sinclair, William E Berquist, Stephanie D Chao, James K Wall
BACKGROUND: Achalasia is a primary esophageal motility disorder characterized by aperistalsis of the esophagus and failed relaxation of the lower esophageal sphincter that presents rarely in childhood. The peroral endoscopic myotomy (POEM) procedure is an emerging treatment for achalasia in adults that has recently been introduced into pediatric surgical practice. METHODS: This is a prospective case series of all children referred to Stanford University Lucile Packard Children's Hospital with manometry-confirmed achalasia who underwent a POEM procedure from 2014 to 2016...
August 9, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28810541/microrna-130a-is-highly-expressed-in-the-esophageal-mucosa-of-achalasia-patients
#18
Hiroyuki Shoji, Hajime Isomoto, Akira Yoshida, Haruo Ikeda, Hitomi Minami, Tsutomu Kanda, Shigetoshi Urabe, Kayoko Matsushima, Fuminao Takeshima, Kazuhiko Nakao, Haruhiro Inoue
Esophageal achalasia is considered as a risk factor of esophageal cancer. The etiologies of esophageal achalasia remain unknown. Peroral endoscopic myotomy (POEM) has recently been established as a minimally invasive method with high curability. The aims of the present study were to identify the microRNAs (miRs) specific to esophageal achalasia, to determine their potential target genes and to assess their alteration following POEM. RNA was extracted from biopsy samples from middle esophageal mucosa and analyzed using a microarray...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28799145/a-third-myotomy-with-peroral-endoscopic-myotomy-after-two-failed-heller-myotomies
#19
Majidah Bukhari, Yamile Haito Chavez, Yen-I Chen, Olaya I Brewer Gutierrez, Mouen A Khashab
No abstract text is available yet for this article.
November 2017: Endoscopy
https://www.readbyqxmd.com/read/28759929/gastric-peroral-endoscopic-myotomy-for-gastroparesis-after-botulinum-toxin-injection
#20
Monica Saumoy, Najib Nassani, Joaquin Ortiz, Viviana Parra, Amy Tyberg, Michel Kahaleh
No abstract text is available yet for this article.
October 2017: Endoscopy
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