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Peroral endoscopic myotomy

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https://www.readbyqxmd.com/read/28916889/teaching-peroral-endoscopic-myotomy-poem-to-surgeons-in-practice-an-into-the-fire-pre-post-test-curriculum
#1
Tomokazu Kishiki, Brittany Lapin, Chi Wang, Brandon Jonson, Lava Patel, Matthew Zapf, Matthew Gitelis, Maria A Cassera, Lee L Swanström, Michael B Ujiki
INTRODUCTION: With the increasing adoption of peroral endoscopic myotomy (POEM) as a first-line therapy for achalasia as well as a growing list of other indications, it is apparent that there is a need for effective training methods for both endoscopists in training and those already in practice. We present a hands-on-focused with pre- and post-testing methodology to teach these skills. METHODS: Six POEM courses were taught by 11 experienced POEM endoscopists at two independent simulation laboratories...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28898921/long-term-quality-of-life-after-peroral-endoscopic-myotomy-remains-compromised-in-patients-with-achalasia-type-iii
#2
Oscar V Hernández Mondragón, Marina A González Martinez, Juan M Blancas Valencia, Maria L Hernandez Reyes, Omar M Solórzano Pineda, Gerardo Blanco Velasco
Background and study aims Peroral endoscopic myotomy (POEM) is an excellent endoscopic treatment for achalasia. Clinical and manometric parameters are used for evaluation and follow-up. However, clinical success does not guarantee high quality of life (QoL) scores, generating doubts about their direct relationship. We aimed to evaluate QoL scores before and after POEM at medium and long term, to evaluate differences between achalasia subtypes and find which factors related to low QoL scores. Patients and methods Achalasia-confirmed patients undergoing POEM between February 2012 and November 2016...
September 12, 2017: Endoscopy
https://www.readbyqxmd.com/read/28867972/peroral-endoscopic-myotomy-for-the-management-of-esophageal-disorders
#3
Ian S Grimm
No abstract text is available yet for this article.
July 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28867969/an-overview-of-achalasia-and-its-subtypes
#4
Dhyanesh A Patel, Brian M Lappas, Michael F Vaezi
Achalasia is one of the most studied esophageal motility disorders. However, the pathophysiology and reasons that patients develop achalasia are still unclear. Patients often present with dysphagia to solids and liquids, regurgitation, and varying degrees of weight loss. There is significant latency prior to diagnosis, which can have nutritional implications. The diagnosis is suspected based on clinical history and confirmed by esophageal high-resolution manometry testing. Esophagogastroduodenoscopy is necessary to rule out potential malignancy that can mimic achalasia...
July 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28859393/open-peroral-endoscopic-myotomy-o-poem-for-the-treatment-of-achalasia
#5
W Liu, H-Z Zeng, H-L Chen, C-C Wu, L-S Ye, B Hu
With the development of endoscopic interventions and inspired by the success of peroral endoscopic myotomy (POEM) for the treatment of achalasia, we investigated an old method of direct peroral endoscopic myotomy without a submucosal tunnel for the treatment of achalasia, which we call open peroral endoscopic myotomy (O-POEM). In this study, Clinical success was achieved in the patient after O-POEM. A reduction of LES pressure, Eckardt score, and a timed barium esophagogram were observed during follow-up. There were no severe complications and no recurrences during two months of follow-up...
October 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28845589/gastrointestinal-peroral-endoscopic-myotomy-for-distal-esophageal-spasm
#6
X Tang, Y Ren, S Huang, X Zhang, W Gong
No abstract text is available yet for this article.
September 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28827050/initial-experience-with-peroral-endoscopic-myotomy-for-treatment-of-achalasia-in-children
#7
William C Kethman, Chad M Thorson, Tiffany J Sinclair, William E Berquist, Stephanie D Chao, James K Wall
BACKGROUND: Achalasia is a primary esophageal motility disorder characterized by aperistalsis of the esophagus and failed relaxation of the lower esophageal sphincter that presents rarely in childhood. The peroral endoscopic myotomy (POEM) procedure is an emerging treatment for achalasia in adults that has recently been introduced into pediatric surgical practice. METHODS: This is a prospective case series of all children referred to Stanford University Lucile Packard Children's Hospital with manometry-confirmed achalasia who underwent a POEM procedure from 2014 to 2016...
August 9, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28810541/microrna-130a-is-highly-expressed-in-the-esophageal-mucosa-of-achalasia-patients
#8
Hiroyuki Shoji, Hajime Isomoto, Akira Yoshida, Haruo Ikeda, Hitomi Minami, Tsutomu Kanda, Shigetoshi Urabe, Kayoko Matsushima, Fuminao Takeshima, Kazuhiko Nakao, Haruhiro Inoue
Esophageal achalasia is considered as a risk factor of esophageal cancer. The etiologies of esophageal achalasia remain unknown. Peroral endoscopic myotomy (POEM) has recently been established as a minimally invasive method with high curability. The aims of the present study were to identify the microRNAs (miRs) specific to esophageal achalasia, to determine their potential target genes and to assess their alteration following POEM. RNA was extracted from biopsy samples from middle esophageal mucosa and analyzed using a microarray...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28799145/a-third-myotomy-with-peroral-endoscopic-myotomy-after-two-failed-heller-myotomies
#9
Majidah Bukhari, Yamile Haito Chavez, Yen-I Chen, Olaya I Brewer Gutierrez, Mouen A Khashab
No abstract text is available yet for this article.
August 10, 2017: Endoscopy
https://www.readbyqxmd.com/read/28759929/gastric-peroral-endoscopic-myotomy-for-gastroparesis-after-botulinum-toxin-injection
#10
Monica Saumoy, Najib Nassani, Joaquin Ortiz, Viviana Parra, Amy Tyberg, Michel Kahaleh
No abstract text is available yet for this article.
July 31, 2017: Endoscopy
https://www.readbyqxmd.com/read/28759922/peroral-endoscopic-myotomy-poem-in-jackhammer-esophagus-a-trick-of-the-trade
#11
Enad Dawod, Monica Saumoy, Ming-Ming Xu, Michel Kahaleh
No abstract text is available yet for this article.
July 31, 2017: Endoscopy
https://www.readbyqxmd.com/read/28756484/distal-esophageal-spasm-with-multiple-esophageal-diverticula-successfully-treated-by-peroral-endoscopic-myotomy
#12
Koji Otani, Shinwa Tanaka, Fumiaki Kawara, Junichi Fujikawa, Akinari Sawada, Risa Uemura, Tetsuya Tanigawa, Toshio Watanabe, Takeshi Azuma, Yasuhiro Fujiwara
Distal esophageal spasm (DES) is a primary esophageal motility disorder. We encountered a rare case of DES accompanied by multiple esophageal diverticula. A 72-year-old woman complained of prolonged dysphagia and chest pain. A barium esophagogram showed multiple esophageal diverticula and significant contraction of the lower esophagus just above the cardia. Esophagogastroduodenoscopy revealed a corkscrew-like appearance, with spiral contractions and diverticula. High-resolution manometry revealed that the integrated relaxation pressure was normal; premature contractions were observed in ≥20% of the swallowing wave; the distal contractile integral was normal...
July 29, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28746968/-french-comment-on-article-submucosal-fibrosis-in-achalasia-patients-is-a-rare-cause-of-aborted-peroral-endoscopic-myotomy-procedures
#13
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Endoscopy
https://www.readbyqxmd.com/read/28745833/full-layer-mucosal-histology-in-achalasia-histological-epithelial-wave-is-characteristic-in-pinstripe-pattern-positive-achalasia
#14
H Sato, K Takahashi, N Nakajima, G Hasegawa, K Mizuno, S Hashimoto, S Ikarashi, K Hayashi, Y Honda, J Yokoyama, Y Sato, S Terai
BACKGROUND: Previously, the mucosal histology in achalasia has only been investigated using superficial biopsy or surgically resected esophageal specimens in end-stage cases. We investigated the histology of the full-layer mucosa in early and advanced achalasia. METHODS: Endoscopy was performed for the pinstripe pattern (PSP) (an early achalasia indicator) and dilation and thickening of the mucosa (advanced achalasia indicators). A mucosal entry site for peroral endoscopic myotomy was created using cap-fitted endoscopic mucosal resection to access the full-layer mucosa and the submucosa...
July 26, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28738013/commentary-on-duan-et-al-a-retrospective-study-of-peroral-endoscopic-full-thickness-myotomy-in-patients-with-severe-achalasia
#15
Carlos Galvani
No abstract text is available yet for this article.
August 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28717439/achalasia-current-therapeutic-options
#16
REVIEW
Zubin Arora, Prashanthi N Thota, Madhusudhan R Sanaka
Achalasia is a chronic incurable esophageal motility disorder characterized by impaired lower esophageal sphincter (LES) relaxation and loss of esophageal peristalsis. Although rare, it is currently the most common primary esophageal motility disorder, with an annual incidence of around 1.6 per 100,000 persons and prevalence of around 10.8/100,000 persons. Symptoms of achalasia include dysphagia to both solids and liquids, regurgitation, aspiration, chest pain and weight loss. As the underlying etiology of achalasia remains unclear, there is currently no curative treatment for achalasia...
June 2017: Therapeutic Advances in Chronic Disease
https://www.readbyqxmd.com/read/28711287/in-vivo-experience-with-poem-an-essential-activity-for-developing-the-technique-in-humans
#17
A Peñaloza-Ramírez, J Suárez-Correa, J Báez-Blanco, C Sabogal-Gómez, H Kuan-Casas, C Sánchez-Pignalosa, P Aponte-Ordóñez
INTRODUCTION AND OBJECTIVES: Achalasia is the most widely studied esophageal motility disorder. No treatment has achieved completely satisfactory results. The laparoscopic Heller esophagomyotomy is currently the most accepted technique. With the advent of minimally invasive surgery, the appearance of peroral endoscopic submucosal myotomy (POEM) has promising results. The primary aim of our study was to perform peroral endoscopic esophagomyotomy in animal experimentation models to perfect the technique and later apply it to humans...
July 12, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28707343/peroral-endoscopic-myotomy-is-safe-and-effective-in-achalasia-patients-aged-older-than-60%C3%A2-years-compared-with-younger-patients
#18
Xiaowei Tang, Yutang Ren, Qiaoping Gao, Silin Huang, Jieqiong Zhou, Xiaofeng Zhang, Jianfeng Yang, Zhengjie Wei, Zhenyu Chen, Bo Jiang, Wei Gong
AIM: Peroral endoscopic myotomy (POEM) has been proven to be effective for treating achalasia, but there are limited data on POEM in elderly patients. We therefore aimed to assess the role of POEM for achalasia in patients aged ≥60 years. METHODS: All consecutive patients that underwent POEM between December 2011 and November 2015 at a single center were retrospectively reviewed. Patients aged ≥60 years were assigned to group A, whereas patients aged <60 years were assigned to group B...
July 14, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28691974/peroral-endoscopic-myotomy-in-children-with-achalasia-a-relatively-long-term-single-center-study
#19
Miao Shijian, Wu Jie, Lu Junping, Wang Yuhuan, Tang Zifei, Zhou Ying, Huang Zhiheng, Ying Huang, Zhou Pinghong
BACKGROUND: Achalasia is a disease caused by neuromuscular dysfunction in the esophagogastric junction, with a relatively low incidence among children. Peroral endoscopic myotomy (POEM) is a new endoscopic procedure for the treatment of achalasia, however it is rarely applied in children. OBJECTIVES: We aim to study the feasibility, safety, and effectiveness of POEM as a treatment for pediatric achalasia. METHODS: A total of 21 pediatric patients (aged from 11 months to 18 years) diagnosed with achalasia and treated with POEM from October of 2014 to October of 2016 in our hospital were included in our study...
July 6, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28691051/peroral-endoscopic-myotomy-using-flushknife-bt-a-single-center-series
#20
Shinwa Tanaka, Takashi Toyonaga, Fumiaki Kawara, Ian S Grimm, Namiko Hoshi, Hirofumi Abe, Yoshiko Ohara, Yoshinori Morita, Eiji Umegaki, Takeshi Azuma
BACKGROUND AND STUDY AIMS : Peroral endoscopic myotomy (POEM) is an evolving new treatment strategy for achalasia. Although several kinds of electrosurgical knives have been used in performing POEM, the best device has yet to be determined. The FlushKnife BT is a waterjet-emitting short needle-knife with a small ball tip (BT) that offers the potential to perform all aspects of POEM with a single device. In this study, we evaluated the safety and efficiency of the FlushKnife BT for POEM...
July 2017: Endoscopy International Open
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