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Peroral endoscopic myotomy

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https://www.readbyqxmd.com/read/29780600/fluoroscopic-gastric-peroral-endoscopic-pyloromyotomy-g-poem-in-patients-with-a-failed-gastric-electrical-stimulator
#1
Abhinav Koul, Sunil Dacha, Parit Mekaroonkamol, Xiaoyu Li, Lianyong Li, Nikrad Shahnavaz, Steven Keilin, Field F Willingham, Jennifer Christie, Qiang Cai
Background: Gastric electrical stimulators (GESs) have been used to treat refractory gastroparesis in patients who fail initial therapies such as dietary modifications, control of psychological stressors and pharmacologic treatment. More recently, gastric peroral endoscopic pyloromyotomy (G-POEM) has emerged as a novel endoscopic technique to treat refractory gastroparesis. We present a case series of patients with refractory gastroparesis who failed treatment with an implanted GES that were safely treated with G-POEM performed under fluoroscopy as a salvage therapy...
May 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29756011/transoral-incisional-fundoplication-for-reflux-after-peroral-endoscopic-myotomy-a-crucial-addition-to-our-arsenal
#2
Amy Tyberg, Anthony Choi, Monica Gaidhane, Michel Kahaleh
Introduction:  Increased esophageal acid exposure is seen in a large percentage of patients with achalasia who undergo peroral endoscopic myotomy (POEM). Endoscopic transoral fundoplication (TIF) is a novel endoscopic technique for the management of patients with chronic gastroesophageal reflux (GERD). We present the first case series evaluating the role of TIF post-POEM. Methods:  Consecutive patients 18 years or older from our academic institution who underwent a POEM procedure and subsequently underwent TIF for symptomatic reflux or regurgitation between December 2014 and June 2017 were included...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29742777/peroral-endoscopic-dual-myotomy-dual-poem-for-achalasia-with-severe-esophageal-dilatation
#3
Xiang-Lei Yuan, Wei Liu, Lian-Song Ye, Ping Yan, Yu Wang, Naveed Khan, Bing Hu
No abstract text is available yet for this article.
May 9, 2018: Endoscopy
https://www.readbyqxmd.com/read/29742769/peroral-endoscopic-myotomy-as-a-versatile-approach-to-treating-complex-esophageal-disorders
#4
Antonella Putignano, Marc Barthet, Ricardo Rio-Tinto, Guido Costamagna, Hubert Louis, Vincent Huberty, Arnaud Lemmers, Jacques Devière
No abstract text is available yet for this article.
May 9, 2018: Endoscopy
https://www.readbyqxmd.com/read/29733014/peroral-endoscopic-myotomy-versus-heller-myotomy-for-achalasia-pros-and-cons
#5
Cristian Tefas, Rami Ababneh, Marcel Tanţău
Achalasia is an esophageal motor disorder that has multiple endoscopic and surgical methods of treatment. However, there is no consensus on optimal therapy in patients suffering from this disorder. This review discusses two therapies with similar but technically different concepts, peroral endoscopic myotomy and Heller surgical myotomy. After a brief introduction to the basic problems of achalasia, technical considerations, intra and postprocedural complications are presented and the advantages and disadvantages of the two procedures are discussed, based on the relevant articles in the literature...
March 2018: Chirurgia
https://www.readbyqxmd.com/read/29712594/poem-for-achalasia
#6
Daniel A Kroch, Ian S Grimm
In 2008, a new treatment modality for esophageal achalasia was introduced-peroral endoscopic myotomy (POEM). POEM is a procedure performed endoscopically, which allows transection of the muscular fibers of the distal esophagus and of the lower esophageal sphincter. The procedure is therefore similar to a laparoscopic Heller myotomy without a fundoplication. Short-term studies have shown that POEM is very effective in relieving dysphagia and regurgitation, but concerns have been raised about the incidence of post-POEM gastroesophageal reflux...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29674757/ten-initial-cases-of-peroral-endoscopic-myotomy-for-treatment-of-esophageal-motility-disorders-at-okayama-university-hospital
#7
Yuusaku Sugihara, Keita Harada, Ryo Kato, Kenji Yamauchi, Shiho Takashima, Daisuke Takei, Yasushi Yamasaki, Toshihiro Inokuchi, Masahiro Takahara, Sakiko Hiraoka, Hiroyuki Okada
Peroral endoscopic myotomy (POEM) for treatment of esophageal motility disorders has recently been reported to be highly effective and less invasive than other treatment. POEM was recently introduced in Okayama University Hospital under the supervision of a physician from a high-volume center. To verify the safety and efficacy of POEM during its introduction in our institution. We examined 10 cases in whom POEM was performed between January 2016 and April 2017. The patients included 7 men and 3 women, with a median age (range) of 49 years (17-74) and median symptom duration of 6 years (1-21)...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29672471/activated-eosinophils-are-present-in-esophageal-muscle-in-patients-with-achalasia-of-the-esophagus
#8
Hong Jin, Bin Wang, Li-Li Zhang, Wei Zhao
BACKGROUND The aim of this study was to undertake a histological evaluation of the presence of eosinophils in esophageal muscle in patients with achalasia before treatment with peroral endoscopic myotomy (POEM), with clinical follow-up at one year. MATERIAL AND METHODS Before treatment, esophageal biopsies including mucosa and esophageal muscle were obtained from 28 patients with achalasia. Nine patients who had undergone esophagectomy for esophageal carcinoma were included in the control group. The Eckardt Score was used to evaluate the clinical symptoms of achalasia...
April 19, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29667413/peroral-endoscopic-myotomy-in-pediatric-jackhammer-esophagus
#9
Rosa Ramos, Martín Alejandro Guidi, Maria Kakisu, Ana Rocca, Paulo Sakai
The jackhammer esophagus is a rare hypercontractile disorder and diagnosis is based on high-resolution manometry. Peroral endoscopic myotomy (POEM) of the spastic esophagus segments has been described. We report a pediatric patient with jackhammer esophagus that was treated endoscopically.
April 18, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29656451/patient-with-mediastinitis-caused-by-delayed-mucosal-damage-after-peroral-endoscopic-myotomy
#10
Hiroki Okada, Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Haruhiro Inoue, Suguru Hasegawa
Peroral endoscopic myotomy (POEM) is a groundbreaking procedure for treating esophageal achalasia, and many reports from various facilities have described its safety and efficacy. However, there have been few reports on adverse events. Here, we report a case of a patient with mediastinitis caused by delayed mucosal damage after POEM. This case was the most severe among all POEM cases at our hospital. A 58-year-old man had experienced dysphagia and chest tightness since he was around 50 years old. At a previous hospital, he had been diagnosed with nonerosive reflux disease and had undergone fundoplication...
April 15, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29653451/fluoroscopy-guided-peroral-endoscopic-myotomy-for-sigmoid-type-achalasia
#11
In Kyung Yoo, Joo Young Cho, Sang Ah Choi, Won Hee Kim, Ki Baik Hahm, Sung Pyo Hong
No abstract text is available yet for this article.
April 13, 2018: Endoscopy
https://www.readbyqxmd.com/read/29649841/gastric-peroral-endoscopic-myotomy-for-the-treatment-of-refractory-gastroparesis-a-multicenter-international-experience
#12
Michel Kahaleh, Jean-Michel Gonzalez, Ming-Ming Xu, Iman Andalib, Monica Gaidhane, Amy Tyberg, Monica Saumoy, Alberto Jose Baptista Marchena, Marc Barthet
BACKGROUND:  Gastroparesis is a difficult-to-treat motility disorder with a poor response to medical therapy. Gastric peroral endoscopic pyloromyotomy (G-POEM) has been offered as a novel therapy in the treatment of refractory gastroparesis. We present a multicenter case series of our experience with G-POEM. METHODS:  This is an international multicenter case series of patients who underwent G-POEM for the treatment of gastroparesis. The severity of gastroparesis was assessed by delayed gastric emptying scintigraphy (GES) and an elevated gastroparesis cardinal symptoms index (GCSI)...
April 12, 2018: Endoscopy
https://www.readbyqxmd.com/read/29617752/muscle-layer-thickness-affects-the-peroral-endoscopic-myotomy-procedure-complexity
#13
D Watanabe, S Tanaka, R Ariyoshi, H Abe, F Kawara, T Toyonaga
Esophageal motility disorders can cause severe dysphagia, regurgitation, and/or noncardiac chest pain due to a lack of coordinated esophageal motility function. However, the clinical significance of esophageal muscle layer thickness remains unclear. The aims of this study are to elucidate the clinical significance of esophageal muscle layer thickness in patients with esophageal motility disorders who undergo peroral endoscopic myotomy (POEM), and to identify predictors of a longer POEM procedure time. Seventy-four consecutive patients with esophageal motility disorders who underwent POEM procedures at Kobe University Hospital from April 2015 to December 2016 were prospectively recruited into this study...
March 28, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29608597/a-clinical-study-of-peroral-endoscopic-myotomy-reveals-that-impaired-lower-esophageal-sphincter-relaxation-in-achalasia-is-not-only-defined-by-high-resolution-manometry
#14
Hiroki Sato, Kazuya Takahashi, Ken-Ichi Mizuno, Satoru Hashimoto, Junji Yokoyama, Shuji Terai
BACKGROUND AND AIM: Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter (LES) relaxation. On high-resolution manometry (HRM), impaired LES relaxation is defined by elevated integrated relaxation pressure (IRP). However, a new category of achalasia within the normal IRP range has been suggested. METHODS: HRM was performed using a Starlet device and an IRP threshold of 26 mmHg. Peroral endoscopic myotomy (POEM) was performed for cases of achalasia diagnosed using established methods...
2018: PloS One
https://www.readbyqxmd.com/read/29608432/treatment-of-achalasia-with-per-oral-endoscopic-myotomy-analysis-of-50-consecutive-patients
#15
Erica D Kane, David J Desilets, Donna Wilson, Marc Leduc, Vikram Budhraja, John R Romanelli
BACKGROUND: Peroral endoscopic myotomy (POEM) has become an acceptable incisionless treatment for achalasia based on encouraging outcomes in multiple series worldwide. This report reflects our early experience. METHODS: Data were collected prospectively on all patients undergoing POEM between June 2011 and April 2016 under IRB approval. Diagnosis of achalasia was confirmed by standard preoperative work-up. Primary outcome was symptom relief, measured by Eckardt score...
April 2, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29587330/-french-comment-on-article-peroral-endoscopic-myotomy-in-treatment-na%C3%A3-ve-achalasia-patients-versus-prior-treatment-failure-cases
#16
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Endoscopy
https://www.readbyqxmd.com/read/29546671/endoscopy-versus-radiology-in-post-procedural-monitoring-after-peroral-endoscopic-myotomy-poem
#17
Jan Friso Nast, Christoph Berliner, Thomas Rösch, Daniel von Renteln, Tania Noder, Guido Schachschal, Stefan Groth, Harald Ittrich, Jan F Kersten, Gerhard Adam, Yuki B Werner
BACKGROUND: The newly developed technique of peroral endoscopic myotomy (POEM) has been shown to be effective in several short- and mid-term studies. Limited information is available about the adequacy of immediate post-POEM monitoring tests. METHODS: POEM was performed under general anesthesia in 228 patients (59.6% male, mean age 45.6 ± 15.5 years). Post-procedural checks comprised clinical and laboratory examination, and, during post-procedure days 1-5, endoscopy and-in the first 114 cases-radiologic examination using water-soluble contrast (1st group); the remaining patients underwent post-procedure controls without radiology (2nd group)...
March 15, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29520414/-treatment-of-achalasia-laparoscopic-heller-myotomy-or-peroral-endoscopic-myotomy
#18
W Schröder, C J Bruns
No abstract text is available yet for this article.
March 8, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29509532/high-resolution-manometry-a-mandatory-examination-in-the-pre-and-postoperative-assessment-of-patients-with-achalasia
#19
Anca Dimitriu, Cristian Gheorghe
High resolution manometry (HRM) is currently the gold standard for the diagnosis of achalasia and other functional esophageal disorders. All patients accusing dysphagia should be endoscopically evaluated prior to manometric investigations in order to rule out pseudoachalasia. The Chicago HRM classification has led to a subclassification of three manometric types of achalasia that seem to have different results to treatment. None of the actual achalasia treatment options are curative. Type II achalasia patients respond best to all treatment options compared to those with types I and III...
January 2018: Chirurgia
https://www.readbyqxmd.com/read/29496268/peroral-endoscopic-myotomy-for-the-treatment-of-achalasia-and-other-esophageal-motor-disorders-short-term-and-medium-term-results-at-a-mexican-tertiary-care-center
#20
O V Hernández-Mondragón, O M Solórzano-Pineda, M A González-Martínez, J M Blancas-Valencia, C Caballero-Luengas
INTRODUCTION AND AIMS: Achalasia is characterized by the absence of lower esophageal sphincter relaxation and esophageal aperistalsis. Diagnosis is confirmed through high-resolution esophageal manometry. Laparoscopic myotomy is the standard treatment, but peroral endoscopic myotomy (POEM) is a safe and effective alternative, with good short-term and medium-term results. Our aim was to describe the short-term and medium-term experience with POEM at a tertiary care center. MATERIALS AND METHODS: The study was conducted within the time frame of November 2014 and February 2017...
February 26, 2018: Revista de Gastroenterología de México
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