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Peroral endoscopic myotomy

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https://www.readbyqxmd.com/read/27895430/full-thickness-myotomy-is-associated-with-higher-rate-of-postoperative-gastroesophageal-reflux-disease
#1
Xue-Hong Wang, Yu-Yong Tan, Hong-Yi Zhu, Chen-Jie Li, De-Liang Liu
AIM: To compare long-term occurrence of gastroesophageal reflux disease (GERD) between two different types of peroral endoscopic myotomy (POEM) for achalasia. METHODS: We included all patients with achalasia who underwent POEM at our hospital from August 2011 to October 2012 and had complete GERD evaluation with ≥ 3 years of follow-up. They were divided into circular or full-thickness myotomy groups according to the depth of myotomy. Demographics, Eckardt score, manometry results, 24-h pH monitoring, and GERD symptoms were recorded and compared between the two groups...
November 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27894140/french-comment-on-article-peroral-endoscopic-myotomy-a-meta-analysis
#2
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Endoscopy
https://www.readbyqxmd.com/read/27894134/peroral-endoscopic-myotomy-ready-for-prime-time-in-all-achalasia-patients
#3
Albert J Bredenoord
No abstract text is available yet for this article.
December 2016: Endoscopy
https://www.readbyqxmd.com/read/27888864/oesophageal-disease-gastroesophageal-reflux-disease-barrett-s-oesophagus-achalasia-and-eosinophilic-oesophagitis
#4
Xavier Calvet
The most interesting conclusions and/or advances presented at Digestive Disease Week 2016 were the following: a) gastroesophageal reflux disease: proton pump inhibitor-refractory reflux disease is frequently associated with poor treatment adherence, psychiatric comorbidities and functional gastrointestinal disorders. These possible entities should be investigated in all cases of proton pump inhibitor-refractory reflux disease; b) Barrett's oesophagus: the efficacy of screening remains unclear; however, new minimally-invasive techniques such as the cytosponge allow more effective detection, both of Barrett's oesophagus and Barrett's oesophagus-associated dysplasia or neoplasia; c) achalasia: evidence indicates that peroral endoscopic myotomy is as effective as surgery and is a safer alternative; d) eosinophilic oesophagitis: high-dose proton pump inhibitors are required to rule out proton pump inhibitor-responsive eosinophilic oesophagitis; montelukast is not clearly effective in the treatment of eosinophilic oesophagitis, although moderate efficacy cannot be ruled out...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27878898/feasibility-and-safety-of-peroral-endoscopic-myotomy-for-achalasia-after-failed-endoscopic-interventions
#5
X Tang, W Gong, Z Deng, J Zhou, Y Ren, Q Zhang, Z Chen, B Jiang
With advances in natural orifice transluminal endoscopic surgery, peroral endoscopic myotomy (POEM) has become a novel treatment for esophageal achalasia. In this study, we investigated the feasibility and safety of POEM in patients with achalasia after failed endoscopic interventions. Data on all patients undergoing POEM treatment of achalasia were collected prospectively. We enrolled 61 patients who underwent POEM for achalasia between July 2011 and January 2014. The preoperative intervention group included patients who had undergone botulinum toxin injection or pneumatic balloon dilation before POEM...
November 23, 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/27864723/pre-treatment-eckardt-score-is-a-simple-factor-for-predicting-one-year-peroral-endoscopic-myotomy-failure-in-patients-with-achalasia
#6
Yutang Ren, Xiaowei Tang, Yanmin Chen, Fengping Chen, Yingying Zou, Zhiliang Deng, Jianuan Wu, Yan Li, Silin Huang, Bo Jiang, Wei Gong
BACKGROUND: Peroral endoscopic myotomy (POEM) is a novel treatment for achalasia with excellent outcomes. But the predictor for treatment failure is not well defined. This study was aimed to prospectively investigate the factors for predicting failed POEM. METHODS: From June 2011 to May 2015, a total of 115 achalasia patients treated by POEM were included for the retrospective cohort study from Nanfang Hospital and the First People's Hospital of Yunnan Province...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27859721/analysis-of-the-learning-curve-of-peroral-endoscopic-myotomy-for-esophageal-achalasia-single-center-two-operator-experience
#7
Lv Houning, Ningning Zhao, Zhongqing Zheng, Tao Wang, Fang Yang, Xihui Jiang, Lin Lin, Chao Sun, Bangmao Wang
OBJECTIVES: Peroral endoscopic myotomy (POEM) has emerged as an advanced technique for the treatment of achalasia, and defining the learning curve is mandatory. METHODS: From August 2011 to June 2014, two operators in our institution (A&B) have performed POEM on 35 and 33 consecutive patients, respectively. The moving average and cumulative sum (CUSUM) methods were employed to analyze the POEM learning curve for corrected operative time (cOT), referring to duration of per centimeter myotomy...
November 17, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27858209/outcomes-in-patients-with-over-1-year-follow-up-after-peroral-endoscopic-myotomy-poem
#8
Marc A Ward, Matt Gitelis, Lava Patel, Yalini Vigneswaran, Joann Carbray, Michael B Ujiki
BACKGROUND: Peroral endoscopic myotomy (POEM) is a promising therapy in the treatment of achalasia. The study was designed to report outcomes, including quality of life, in patients with at least 1-year follow-up. METHODS: Patients from an institutional review board-approved protocol underwent POEM and were followed prospectively. Health-related quality of life was measured preoperatively and 1 year post-operatively using Short Form-36 Health Survey version 2 (SF-36v2)...
November 17, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27855465/from-poem-to-poet-applications-and-perspectives-for-submucosal-tunnel-endoscopy
#9
Philip W Y Chiu, Haruhiro Inoue, Thomas Rösch
Recent advances in submucosal endoscopy have unlocked a new horizon for potential development in diagnostic and therapeutic endoscopy. Increasing evidence has demonstrated that peroral endoscopic myotomy (POEM) is not only clinically feasible and safe, but also has excellent results in symptomatic relief of achalasia. The success of submucosal endoscopy in performance of tumor resection has confirmed the potential of this new area in diagnostic and therapeutic endoscopy. This article reviews the current applications and evidence, from POEM to peroral endoscopic tunnel resection (POET), while exploring the possible future clinical applications in this field...
December 2016: Endoscopy
https://www.readbyqxmd.com/read/27788547/french-comment-on-article-major-perioperative-adverse-events-of-peroral-endoscopic-myotomy-a-systematic-5-year-analysis
#10
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Endoscopy
https://www.readbyqxmd.com/read/27788540/peroral-endoscopic-myotomy-minimally-invasive-but-truly-surgical
#11
Lee L Swanström
No abstract text is available yet for this article.
November 2016: Endoscopy
https://www.readbyqxmd.com/read/27747277/single-clips-versus-multi-firing-clip-device-for-closure-of-mucosal-incisions-after-peroral-endoscopic-myotomy-poem
#12
Tessa Verlaan, Fraukje A M Ponds, Barbara A J Bastiaansen, Albert J Bredenoord, Paul Fockens
: Background and aims: After Peroral Endoscopic Myotomy (POEM), the mucosal incision is closed with endoscopically applied clips. After each clip placement, a subsequent clipping device has to be introduced through the working channel. With the Clipmaster3, three consecutive clips can be placed without reloading which could reduce closure time. We performed a prospective study evaluating efficacy, safety, and ease of use. Closure using Clipmaster3 was compared to closure with standard clips...
October 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27741529/use-of-cyanoacrylate-to-treat-mucosal-perforations-during-or-after-peroral-endoscopic-myotomy
#13
Oscar Víctor Hernández-Mondragón, Omar Michel Solórzano-Pineda, Gerardo Blanco-Velasco, Juan Manuel Blancas-Valencia
No abstract text is available yet for this article.
January 2016: Endoscopy
https://www.readbyqxmd.com/read/27699951/muscle-layer-histopathology-and-manometry-pattern-of-primary-esophageal-motility-disorders-including-achalasia
#14
N Nakajima, H Sato, K Takahashi, G Hasegawa, K Mizuno, S Hashimoto, Y Sato, S Terai
BACKGROUND: Histopathology of muscularis externa in primary esophageal motility disorders has been characterized previously. We aimed to correlate the results of high-resolution manometry with those of histopathology. METHODS: During peroral endoscopic myotomy, peroral esophageal muscle biopsy was performed in patients with primary esophageal motility disorders. Immunohistochemical staining for c-kit was performed to assess the interstitial cells of Cajal (ICCs)...
October 3, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27699518/long-term-outcome-of-peroral-endoscopic-myotomy-for-esophageal-achalasia-in-patients-with-previous-heller-myotomy
#15
Helle Ø Kristensen, Jakob Kirkegård, Daniel Willy Kjær, Frank Viborg Mortensen, Rastislav Kunda, Niels Christian Bjerregaard
BACKGROUND: Peroral endoscopic myotomy (POEM) is an emerging procedure in the treatment of esophageal achalasia, a primary motility disorder. However, the long-term outcome of POEM in patients, who have previously undergone a Heller myotomy, is unknown. METHODS: Using a local database, we identified patients with esophageal achalasia, who underwent POEM. We compared patients with a previous Heller myotomy to those, who had received none or only non-surgical therapy prior to the POEM procedure...
October 3, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27692369/-tension-pneumothorax-during-peroral-endoscopic-myotomy-for-treatment-of-esophageal-achalasia-under-general-anesthesia
#16
Tsung-Shih Li, Tsung-Yang Lee, Kate Hsiurong Liao
More and more endoscopically gastrointestinal procedures require anesthesiologists to perform general anesthesia, such as "peroral endoscopic myotomy". Peroral endoscopic myotomy is a novel invasive treatment for the primary motility disorder of esophagus, called esophageal achalasia. Despite of its minimally invasive feature, there are still complications during the procedure which develop to critical conditions and threat patients' lives. Herein we describe a case about tension pneumothorax subsequent to esophageal rupture during peroral endoscopic myotomy...
September 27, 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/27687234/finding-the-right-treatment-for-achalasia-treatment-risks-efficacy-complications
#17
An Moonen, Guy Boeckxstaens
Achalasia is a primary esophageal motor disorder of the esophagus that is characterized by the absence of esophageal peristalsis and a failure of the lower esophageal sphincter (LES) to relax upon swallowing. The defective relaxation leads to symptoms of dysphagia for solids and liquids, regurgitation, aspiration, chest pain, and weight loss. Achalasia is believed to result from a selective loss of enteric inhibitory neurons, most likely due to an autoimmune phenomenon in genetic susceptible individuals. As there is no curative treatment for achalasia, treatment is confined to disruption of the LES to improve bolus passage...
September 29, 2016: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/27669470/peroral-endoscopic-myotomy-for-sigmoid-type-achalasia-the-myotomy-length-and-ways-to-facilitate-the-procedure
#18
Yuyong Tan, Deliang Liu, Jirong Huo
No abstract text is available yet for this article.
October 2016: Endoscopy
https://www.readbyqxmd.com/read/27649684/peroral-endoscopic-myotomy-versus-pneumatic-dilation-for-achalasia-in-patients-aged-%C3%A2-65-years
#19
Xuehong Wang, Yuyong Tan, Liang Lv, Hongyi Zhu, Yi Chu, Chenjie Li, Deliang Liu
BACKGROUND AND AIM: Both peroral endoscopic myotomy (POEM) and pneumatic dilation (PD) has proved to be effective for treating achalasia in patients aged ≥ 65 years. However little is known about the comparison between POEM and PD. The aim of the study was to compare the safety and efficacy of POEM and PD for the treatment of achalasia in these patients. METHODS: We retrospectively reviewed the medical records of patients aged 65 years-old or more who received POEM or PD for the treatment of achalasia at our hospital from January 2010 to December 2015, they were divided into the POEM group and the PD group...
October 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27633440/safety-and-efficacy-of-poem-for-treatment-of-achalasia-a-systematic-review-of-the-literature
#20
Oscar M Crespin, Louis W C Liu, Ambica Parmar, Timothy D Jackson, Jemila Hamid, Eran Shlomovitz, Allan Okrainec
INTRODUCTION: Peroral endoscopic myotomy (POEM) is a novel intervention for the treatment of achalasia, which combines the advantages of endoscopic access and myotomy. The purpose of this study was to perform a systematic review of the literature to evaluate the efficacy and safety of POEM. METHODS: The systematic review was conducted following the PRISMA guidelines. Evidence-Based Medicine Reviews, Cochrane Central Register of Controlled Trials, Ovid MEDLINE (R) including in-process and non-indexed citations were searched for POEM studies using the keywords: esophageal achalasia, POEM, endoscopy, natural orifice surgery, laparoscopic Heller myotomy (LHM), and related terms...
September 15, 2016: Surgical Endoscopy
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