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https://www.readbyqxmd.com/read/29783282/sustained-conduction-of-vasomotor-responses-in-rat-mesenteric-arteries-in-a-two-compartment-in-vitro-setup
#1
Teresa Palao, Angela van Weert, Anne de Leeuw, Judith de Vos, Erik N T P Bakker, Ed van Bavel
AIM: Conduction of vasomotor responses may contribute to long-term regulation of resistance artery function and structure. Most previous studies have addressed conduction of vasoactivity only during very brief stimulations. We developed a novel setup that allows the local pharmacological stimulation of arteries in vitro for extended periods of time, and studied the conduction of vasomotor responses in rat mesenteric arteries under those conditions. METHODS: The new in vitro set up was based on the pressure myograph...
May 21, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29783215/the-changes-of-some-bioregulators-and-gas-transmitters-in-patients-with-hypertonic-disease-under-the-influence-of-physical-loading
#2
Iryna S Dronyk, Ostap H Yavorsky, Olexandr Y Sklyarov
OBJECTIVE: Introduction: Nowadays arterial hypertension is supposed to be a pathogenetic factor of numerous cardiovascular diseases (CVD) and 18% cases of the preterm death. Due to the data of the American Heart Association in 77% of patients, who had stroke, the arterial pressure overexceeded 140/90 mm Hg. In Ukraine, according to the epidemiologic study more than 1/3 of the population have increased arterial pressure. One of the extremely important aspects of struggle with CVD is diagnosis and prevention of hypertonic disease...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783166/in-situ-sludge-reduction-and-carbon-reuse-in-an-anoxic-oxic-process-coupled-with-hydrocyclone-breakage
#3
Yinxiang Xu, Yuanyuan Fang, Zhenhua Wang, Dan Guo, Yi Liu, Yuan Huang, Pengbo Fu, Juehui Jin, Chenwen Wei, Hualin Wang, Tao Zeng
The long-term performance of an anoxic-oxic-hydrocyclone (AOH) process with an in-situ hydrocyclone treatment unit in the mixed liquid return line for sludge reduction and carbon reuse has been observed, in comparison with a conventional anoxic-oxic (AO) process. Three parallel side-stream systems, including one AOH25 system with a 25-mm hydrocyclone, one AOH35 system with a 35-mm hydrocyclone and one AO system, were built and fed with real wastewater for a comparative study in a wastewater treatment plant...
May 9, 2018: Water Research
https://www.readbyqxmd.com/read/29783086/biomechanical-comparison-of-cemented-vs-non-cemented-anterior-screw-fixation-in-type-ii-odontoid-fractures-in-the-elderly-a-cadaveric-study
#4
Petr Rehousek, Edward Jenner, James Holton, Marcin Czyz, Lukas Capek, Petr Henys, Marketa Kulvajtova, Martin Krbec, Jiri Skala-Rosenbaum
Background Context Odontoid process fractures are the most common injuries of the cervical spine in the elderly. Anterior screw stabilisation of type 2 odontoid process fractures improves survival and function in these patients but may be complicated by failure of fixation. Purpose To determine whether cement augmentation of a standard anterior screw provides biomechanically superior fixation of type II odontoid fractures in comparison to a non-cemented standard screw. Study design Twenty human cadaveric C2 vertebrae from elderly donors (mean age 83 years) were obtained...
May 18, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29783066/safe-needle-approach-for-examination-of-the-rhomboid-major
#5
Ki Hoon Kim, Goo Young Kim, Seong Gyu Lim, Byung Kyu Park, Dong Hwee Kim
BACKGROUND: Safe and accurate needle access to the rhomboid major (RM) during electromyography is challenging due to the overlying trapezius muscle and the risk of pneumothorax. OBJECTIVE: To investigate the RM anatomy associated with the trapezius using ultrasonography and to determine a safe and accurate needle insertion point for needle electromyography of the RM. DESIGN: Descriptive study. SETTING: Department of physical medicine and rehabilitation of a tertiary clinic center PARTICIPANTS: Participants between 23 and 71 years of age without any diseases (N=25; 13 men, 12 women; 50 scapulae) were included...
May 18, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29783056/treatment-of-winery-wastewater-by-anodic-oxidation-using-bdd-electrode
#6
Christian Candia-Onfray, Nicole Espinoza, Evanimek B Sabino da Silva, Carla Toledo-Neira, L Carolina Espinoza, Rocío Santander, Verónica García, Ricardo Salazar
The effective removal of organics from winery wastewater was obtained in real residual effluents from the wine industry using anodic oxidation (AO). The effluent had an initial organic load of [COD]0 of 3490 mg L-1 equal to [TOC]0 of 1320 mg L-1 . In addition, more than 40 organic compounds were identified by means of GC-MS. Different density currents as well as the addition of electrolytes were tested during electrolysis. The results show the decay of [COD]t by 63.6% when no support electrolyte was added, whereas almost total mineralization and disinfection was reached after adding of 50 mM of sodium sulfate and sodium chloride and applying higher density currents...
May 4, 2018: Chemosphere
https://www.readbyqxmd.com/read/29783001/laparoscopic-extraperitoneal-pelvic-lymph-node-debulking-in-locally-advanced-cervical-cancer
#7
Diaz-Feijoo Berta, Luna-Guibourg Rocio, Cabrera Silvia, Manrique Susana, Gil-Moreno Antonio
OBJECTIVE: To demonstrate the feasibility of laparoscopic extraperitoneal approach for pelvic metastatic lymph node debulking in locally advanced cervical cancer. DESIGN: Surgical video article. Canadian task force Classification III. SETTING: University Hospital PATIENT: A 52 year-old patient presented a stage IIA2 Cervical adenocarcinoma according to FIGO classification. The physical exam reported a 45 mm tumor. Positron emission tomography (PET- CT) was positive for hypermetabolic enlarged lymph nodes in left external iliac region of 1...
May 18, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29782842/paraoxonase-1-pon1-l55m-among-common-variants-in-the-coding-region-of-the-paraoxonase-gene-family-may-contribute-to-the-glycemic-control-in-type-2-diabetes
#8
Abdolkarim Mahrooz, Mohammad Bagher Hashemi-Soteh, Masoud Heydari, Ruzbeh Boorank, Fatemeh Ramazani, Ali Mahmoudi, Anvarsadat Kianmehr, Ahad Alizadeh
OBJECTIVE: Genome studies have shown that the genes encoding paraoxonase 1 (PON1) and PON2 are associated with glucose metabolism. The goal of this study was to simultaneously evaluate the association between functional variants in PON1 and PON2 genes and susceptibility for type 2 diabetes (T2D) and determine whether they can affect glycemic control. METHODS: We performed a case-control study with 145 newly diagnosed patients with T2D and 148 controls. The common variants including PON1-Q192R, PON1-L55M and PON2-S311C were genotyped by PCR-based RFLP...
May 18, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29782837/phenylalanine-and-tryptophan-stimulate-gastrin-and-somatostatin-secretion-and-h-k-atpase-activity-in-pigs-through-calcium-sensing-receptor
#9
Yihan Xian, Xiuying Zhao, Chao Wang, Cuicui Kang, Liren Ding, Weiyun Zhu, Suqin Hang
In rodents and humans, aromatic amino acids increase gut hormone secretion and H+ -K+ -ATPase activity by modulating calcium-sensing receptor (CaSR). However, the role of CaSR and its related signaling molecules in amino acid-induced gut hormone secretion in swine has not been investigated. Here, we examined whether a CaSR-dependent pathway modulated gastrin and somatostatin (SS) secretion and H+ -K+ -ATPase activity in pigs. Perfusion of pig stomach tissues in the presence of extracellular 80 mM l-phenylalanine (Phe) or 20 mM l-tryptophan (Trp) and a CaSR agonist cinacalcet triggered gastrin and SS secretion and H+ -K+ -ATPase activity (P < 0...
May 18, 2018: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29782812/what-variables-are-associated-with-the-outcome-of-arthroscopic-lysis-and-lavage-surgery-for-internal-derangement-of-the-temporomandibular-joint
#10
Tyler H Haeffs, Lindsay N D'Amato, Shehryar N Khawaja, David A Keith, Steven J Scrivani
PURPOSE: Arthroscopic lysis and lavage surgery (AS) is an effective modality that can decrease pain and increase maximum interincisal opening (MIO) in patients with internal derangement (ID) of the temporomandibular joint (TMJ). However, some patients remain in pain or have limited mandibular range of motion despite AS. The purpose of this study was to determine the effectiveness, prevalence of adverse effects, and predictors of response to TMJ AS in patients with TMJ arthralgia and ID...
April 26, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29782664/stereoselective-hplc-separation-of-alvimopan-on-cellulose-based-immobilized-polysaccharide-as-a-chiral-stationary-phase
#11
Nitin H Dhekale, Dattatray B Gunjal, Anil H Gore, Yagnakirankumar Komaravolu, K Hima Bindu, Govind B Kolekar
Chiral separation by normal phase high performance liquid chromatography is one of the most powerful technique to quantify the chiral purity of the compounds. In this study, a novel, simple, and specific analytical method was proposed to ascertain the chiral purity of alvimopan (ALV). The normal phase HPLC method was developed based on cellulose tris (3,5-dichlorophenylcarbamate) stationary phase. The separation of ALV isomers achieved by using column CHIRALPAK IC (250 × 4.6 mm, 5 μm), mobile phase n-hexane: isopropyl alcohol: ethanol: diethylamine (650:200:150:5 v/v), column oven temperature 30°C, flow rate 1...
May 21, 2018: Chirality
https://www.readbyqxmd.com/read/29782659/self-suspended-nanomesh-scaffold-for-ultrafast-flexible-photodetectors-based-on-organic-semiconducting-crystals
#12
Lei Zhang, Nadiia Pasthukova, Yifan Yao, Xiaolan Zhong, Egon Pavlica, Gvido Bratina, Emanuele Orgiu, Paolo Samorì
Self-standing nanostructures are of fundamental interest in materials science and nanoscience and are widely used in (opto-)electronic and photonic devices as well as in micro-electromechanical systems. To date, large-area and self-standing nanoelectrode arrays assembled on flexible substrates have not been reported. Here the fabrication of a hollow nanomesh scaffold on glass and plastic substrates with a large surface area over 1 mm2 and ultralow leakage current density (≈1-10 pA mm-2 @ 2 V) across the empty scaffold is demonstrated...
May 21, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29782613/on-the-optimization-of-low-cost-fdm-3d-printers-for-accurate-replication-of-patient-specific-abdominal-aortic-aneurysm-geometry
#13
Michael Chung, Norbert Radacsi, Colin Robert, Edward D McCarthy, Anthony Callanan, Noel Conlisk, Peter R Hoskins, Vasileios Koutsos
Background: There is a potential for direct model manufacturing of abdominal aortic aneurysm (AAA) using 3D printing technique for generating flexible semi-transparent prototypes. A patient-specific AAA model was manufactured using fused deposition modelling (FDM) 3D printing technology. A flexible, semi-transparent thermoplastic polyurethane (TPU), called Cheetah Water (produced by Ninjatek, USA), was used as the flexible, transparent material for model manufacture with a hydrophilic support structure 3D printed with polyvinyl alcohol (PVA)...
2018: 3D Print Med
https://www.readbyqxmd.com/read/29782588/ground-glass-pulmonary-nodules-their-significance-in-oncology-patients-and-the-role-of-computer-tomography-and-18f-fluorodeoxyglucose-positron-emission-tomography
#14
Laura Evangelista, Annalori Panunzio, Elena Scagliori, Paolo Sartori
Objective: to determine the clinical significance of ground glass pulmonary nodules, either pure (GGNs) or mixed with the presence of solid component (MPNs), in patients with known pulmonary or extra-thoracic malignancies and to evaluate the role of computed tomography (CT) and positron emission tomography (PET)/CT in their diagnosis and follow-up. Methods: A total of 130 nodules in 68 patients were revealed: 119 GGNs and 11 MPNs. GGN lesions were found in 58 patients, MPNs in eight, and in two cases, both...
2018: Eur J Hybrid Imaging
https://www.readbyqxmd.com/read/29782446/minimally-invasive-proximal-interphalangeal-joint-arthrodesis-using-headless-screw-surgical-technique
#15
Elizabeth A Newman, Maria C Orbay, Fiesky A Nunez, Fiesky Nunez
Proximal interphalangeal (PIP) joint arthritis causes debilitating hand pain and instability leading to significant functional impairment. Arthrodesis remains the gold standard for treatment of PIP arthritis. We present a minimally invasive PIP arthrodesis that provides rigid fixation with a headless compression screw. Seven patients who presented to the senior author with PIP joint arthritis underwent PIP arthrodesis by minimally invasive technique. A 1 cm transverse incision is made over the PIP joint, incising skin, central band, and articular capsule...
June 2018: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29782335/novel-placement-of-cortical-bone-trajectory-screws-in-the-lumbar-spine-a-radiographic-and-cadaveric-study
#16
Hai Gao, Renjie Zhang, Chongyu Jia, Tao Xing, Jianxiang Zhang, Fulong Dong, Peng Ge, Peiwen Song, Peng Xu, Huaqing Zhang, Huimin Li, Cailiang Shen
STUDY DESIGN: This is a radiographic and cadaveric study. OBJECTIVE: The aim of this study was to conduct a detailed comparison about the parameters between the ideal cortical bone trajectory (CBT) and practical CBT screw. SUMMARY OF BACKGROUND DATA: CBT screws have recently become popular in spinal surgery, mainly because of their improved fixation while minimizing soft tissue dissection. However, to our knowledge, no previous study has provided a detailed comparison on the parameters between the ideal CBT and practical CBT screws...
May 18, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29782307/cutaneous-manifestations-of-tuberous-sclerosis
#17
Mirjana Bakić, Marina Ratković, Branka Gledović, Balsa Vujović, Danilo Radunović, Vera Babić, Vladimir Prelević
Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). There are two different genetic loci responsible for TS: 9q34 (TSC1-hamartin) and 16p13...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782304/role-of-in-vivo-reflectance-confocal-microscopy-in-the-analysis-of-melanocytic-lesions
#18
Elena-Daniela Serban, Francesca Farnetani, Giovanni Pellacani, Maria Magdalena Constantin
Worldwide melanoma incidence and mortality are increasing (1). Despite the ongoing research, advanced melanoma is still incurable; therefore, the most appropriate solution seems to be early detection combined with complete surgical excision (2). Since the diagnostic protocol of suspicious lesions includes a complete excision with safety margins (2), the problem of unnecessary scarring is significant. The real challenge in this case is to have a properly formulated diagnosis before acquiring a biopsy. Currently available non-invasive techniques are coherence tomography, digital dermoscopy, and reflectance confocal microscopy...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#19
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782256/-radiofrequency-pulmonary-artery-ablation-for-treatment-of-residual-pulmonary-hypertension-after-pulmonary-endarterectomy
#20
A M CHernyavskiy, A G Edemskiy, N V Novikova, A B Romanov, S N Artemenko, B A Rudenko, A R Tarkova
OBJECTIVE: to assess the safety and efficiency of radiofrequency pulmonary artery ablation for treatment of residual pulmonary hypertension after pulmonary endarterectomy. MATERIAL AND METHODS: Radiofrequency pulmonary artery denervation (PADN) was performed in 16 patients (10 men, mean age 39 years [26; 51]). Indication for PADN was mean pulmonary artery pressure (PAP) >25 mm Hg with absence of proximal pulmonary artery lesion according to computer tomography...
April 2018: Kardiologiia
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