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https://www.readbyqxmd.com/read/28441229/preliminary-model-for-the-design-of-a-custom-middle-ear-prosthesis
#1
Brandon Kamrava, Jonathan A Gerstenhaber, Mamta Amin, Yah-El Har-El, Pamela C Roehm
HYPOTHESIS: Custom prostheses could be used to recreate the ossicular chain and improve hearing. BACKGROUND: Ossicular discontinuity or fixation occurs in 55% of cases of conductive hearing loss, with most cases involving the incus. Reconstruction has been achieved by a variety of methods; however, there has been little improvement in hearing outcomes in decades. METHODS: Precise measurements of anatomic dimensions, weight, and center of gravity were taken from 19 cadaveric incudes...
April 24, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28366210/3d-printed-led-based-on-capillary-detector-housing-with-integrated-slit
#2
Farhan Cecil, Min Zhang, Rosanne M Guijt, Alan Henderson, Pavel N Nesterenko, Brett Paull, Michael C Breadmore, Mirek Macka
A 3D printed photometric detector body with integrated slit was fabricated to position a LED and photodiode either side of capillary tubing using a fused deposition modelling (FDM) printer. To make this approach suitable for capillaries down to 50 μm i.d. the dimension of the in-built slit is the critical element of the printed housing. The spatial orientation of the model for printing was found to significantly impact on the resolution of the structures and voids that can be printed. By designing a housing with a slit positioned in the XY plane in parallel with the print direction, the narrowest void (slit) that could be printed was 70 μm...
May 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28362934/three-dimensional-printed-modeling-of-diffuse-low-grade-gliomas-and-associated-white-matter-tract-anatomy
#3
Jayesh P Thawani, Nickpreet Singh, Jared M Pisapia, Kalil G Abdullah, Drew Parker, Bryan A Pukenas, Eric L Zager, Ragini Verma, Steven Brem
BACKGROUND: Diffuse low-grade gliomas (DLGGs) represent several pathological entities that infiltrate and invade cortical and subcortical structures in the brain. OBJECTIVE: To describe methods for rapid prototyping of DLGGs and surgically relevant anatomy. METHODS: Using high-definition imaging data and rapid prototyping technologies, we were able to generate 3 patient DLGGs to scale and represent the associated white matter tracts in 3 dimensions using advanced diffusion tensor imaging techniques...
April 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28299927/supramolecular-hydrogels-based-on-dna-self-assembly
#4
Yu Shao, Haoyang Jia, Tianyang Cao, Dongsheng Liu
Extracellular matrix (ECM) provides essential supports three dimensionally to the cells in living organs, including mechanical support and signal, nutrition, oxygen, and waste transportation. Thus, using hydrogels to mimic its function has attracted much attention in recent years, especially in tissue engineering, cell biology, and drug screening. However, a hydrogel system that can merit all parameters of the natural ECM is still a challenge. In the past decade, deoxyribonucleic acid (DNA) has arisen as an outstanding building material for the hydrogels, as it has unique properties compared to most synthetic or natural polymers, such as sequence designability, precise recognition, structural rigidity, and minimal toxicity...
March 16, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28292595/microguided-endodontics-accuracy-of-a-miniaturized-technique-for-apically-extended-access-cavity-preparation-in-anterior-teeth
#5
Thomas Connert, Marc S Zehnder, Roland Weiger, Sebastian Kühl, Gabriel Krastl
INTRODUCTION: The aim of this study was to assess the accuracy of guided endodontics in mandibular anterior teeth by using miniaturized instruments. This technique is designed to treat teeth with pulp canal calcifications and narrow roots by using a printed template that guides a bur to the calcified root canal. METHODS: Sixty sound mandibular anterior teeth were used in 10 mandibular models. Preoperative surface and cone-beam computed tomography scans were matched by using the coDiagnostix software...
May 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28274121/dynamics-of-capillary-driven-flow-in-3d-printed-open-microchannels
#6
Robert K Lade, Erik J Hippchen, Christopher W Macosko, Lorraine F Francis
Microchannels have applications in microfluidic devices, patterns for micromolding, and even flexible electronic devices. Three-dimensional (3D) printing presents a promising alternative manufacturing route for these microchannels due to the technology's relative speed and the design freedom it affords its users. However, the roughness of 3D printed surfaces can significantly influence flow dynamics inside of a microchannel. In this work, open microchannels are fabricated using four different 3D printing techniques: fused deposition modeling (FDM), stereolithography (SLA), selective laser sintering, and multi jet modeling...
March 16, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28269344/inductive-power-transmission-to-millimeter-sized-biomedical-implants-using-printed-spiral-coils
#7
Ahmed Ibrahim, Mehdi Kiani
The operation frequency (f) has been a key parameter in optimizing wireless power transmission links for biomedical implants with millimeter (mm) dimensions. This paper studies the feasibility of using printed spiral coils (PSCs) for powering mm-sized implants with high power transmission efficiency (PTE) at different fps. Compared to wire-wound coils (WWCs), using a PSC in the implant side allows batch fabrication on rigid or flexible substrates, which can also be used as a platform for integrating implant components...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268718/a-new-crank-arm-based-load-cell-with-built-in-conditioning-circuit-and-strain-gages-to-measure-the-components-of-the-force-applied-by-a-cyclist
#8
Andre V Pigatto, Karina O A Moura, Gabriela W Favieiro, Alexandre Balbinot
This report describes the development of a force platform based on instrumented load cells with built-in conditioning circuit and strain gages to measure and acquire the components of the force that is applied to the bike crank arm during pedaling in real conditions, and save them on a SD Card. To accomplish that, a complete new crank arm 3D solid model was developed in the SolidWorks, with dimensions equivalent to a commercial crank set and compatible with a conventional road bike, but with a compartment to support all the electronics necessary to measure 3 components of the force applied to the pedal during pedaling...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227586/inductive-power-transmission-to-millimeter-sized-biomedical-implants-using-printed-spiral-coils
#9
Ahmed Ibrahim, Mehdi Kiani, Ahmed Ibrahim, Mehdi Kiani, Ahmed Ibrahim, Mehdi Kiani
The operation frequency (f) has been a key parameter in optimizing wireless power transmission links for biomedical implants with millimeter (mm) dimensions. This paper studies the feasibility of using printed spiral coils (PSCs) for powering mm-sized implants with high power transmission efficiency (PTE) at different fps. Compared to wire-wound coils (WWCs), using a PSC in the implant side allows batch fabrication on rigid or flexible substrates, which can also be used as a platform for integrating implant components...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226906/a-new-crank-arm-based-load-cell-with-built-in-conditioning-circuit-and-strain-gages-to-measure-the-components-of-the-force-applied-by-a-cyclist
#10
Andre V Pigatto, Karina O A Moura, Gabriela W Favieiro, Alexandre Balbinot, Andre V Pigatto, Karina O A Moura, Gabriela W Favieiro, Alexandre Balbinot, Karina O A Moura, Gabriela W Favieiro, Alexandre Balbinot, Andre V Pigatto
This report describes the development of a force platform based on instrumented load cells with built-in conditioning circuit and strain gages to measure and acquire the components of the force that is applied to the bike crank arm during pedaling in real conditions, and save them on a SD Card. To accomplish that, a complete new crank arm 3D solid model was developed in the SolidWorks, with dimensions equivalent to a commercial crank set and compatible with a conventional road bike, but with a compartment to support all the electronics necessary to measure 3 components of the force applied to the pedal during pedaling...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28188705/design-construction-and-optimization-of-a-novel-modular-and-scalable-incubation-chamber-for-continuous-viral-inactivation
#11
Raquel Orozco, Linus Amarikwa, Stephanie Parker, Scott Godfrey, Lindsay Hernandez, Chinenye Wachuku, Ben Mai, Brian Song, Shashidhar Hoskatti, Jinkeng Asong, Marcus Fiadeiro, Parviz Shamlou, Cameron Bardliving, Jon Coffman
We designed, built or 3D printed, and screened tubular reactors that minimize axial dispersion to serve as incubation chambers for continuous virus inactivation of biological products. Empirical residence time distribution data were used to derive each tubular design's volume equivalent to a theoretical plate (VETP) values at a various process flow rates. One design, the Jig In a Box (JIB), yielded the lowest VETP, indicating optimal radial mixing and minimal axial dispersion. A minimum residence time (MRT) approach was employed, where the MRT is the minimum time the product spends in the tubular reactor...
February 11, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28112418/intrinsic-dependencies-of-ct-radiomic-features-on-voxel-size-and-number-of-gray-levels
#12
Muhammad Shafiq-Ul-Hassan, Geoffrey G Zhang, Kujtim Latifi, Ghanim Ullah, Dylan C Hunt, Yoganand Balagurunathan, Mahmoud Abrahem Abdalah, Matthew B Schabath, Dmitry G Goldgof, Dennis Mackin, Laurence Edward Court, Robert James Gillies, Eduardo Gerardo Moros
PURPOSE: Many radiomics features were originally developed for non-medical imaging applications and therefore original assumptions may need to be reexamined. In this study, we investigated the impact of slice thickness and pixel spacing (or pixel size) on radiomics features extracted from Computed Tomography (CT) phantom images acquired with different scanners as well as different acquisition and reconstruction parameters. The dependence of CT texture features on gray-level discretization was also evaluated...
March 2017: Medical Physics
https://www.readbyqxmd.com/read/28049583/purification-of-semiconducting-single-walled-carbon-nanotubes-by-spiral-counter-current-chromatography
#13
Martha Knight, Rodrigo Lazo-Portugal, Saeyoung Nate Ahn, Steingrimur Stefansson
Over the last decade man-made carbon nanostructures have shown great promise in electronic applications, but they are produced as very heterogeneous mixtures with different properties so the achievement of a significant commercial application has been elusive. The dimensions of single-wall carbon nanotubes are generally a nanometer wide, up to hundreds of microns long and the carbon nanotubes have anisotropic structures. They are processed to have shorter lengths but they need to be sorted by diameter and chirality...
February 3, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28046475/su-f-e-13-design-and-fabrication-of-gynacological-brachytherapy-shielding-non-shielding-applicators-using-indigenously-developed-3d-printing-machine
#14
S Shanmugam
PURPOSE: In this innovative work we have developed Gynecological Brachytherapy shielding & Non Shielding Applicators and compared with the commercially available applicators by using the indigenously developed 3D Printing machine. METHODS: We have successfully indigenously developed the 3D printing machine. Which contain the 3 dimensional motion platform, Heater unit, base plate, ect… To fabricate the Gynecological Brachytherapy shielding & non shielding applicators the 3D design were developed in the computer as virtual design...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28024776/comparison-of-reconstructed-rapid-prototyping-models-produced-by-3-dimensional-printing-and-conventional-stone-models-with-different-degrees-of-crowding
#15
COMPARATIVE STUDY
Wan Nurazreena Wan Hassan, Yusnilawati Yusoff, Noor Azizi Mardi
INTRODUCTION: Rapid prototyping models can be reconstructed from stereolithographic digital study model data to produce hard-copy casts. In this study, we aimed to compare agreement and accuracy of measurements made with rapid prototyping and stone models for different degrees of crowding. METHODS: The Z Printer 450 (3D Systems, Rock Hill, SC) reprinted 10 sets of models for each category of crowding (mild, moderate, and severe) scanned using a structured-light scanner (Maestro 3D, AGE Solutions, Pisa, Italy)...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27895985/multi-channel-multi-distance-broadband-near-infrared-spectroscopy-system-to-measure-the-spatial-response-of-cellular-oxygen-metabolism-and-tissue-oxygenation
#16
Phong Phan, David Highton, Jonathan Lai, Martin Smith, Clare Elwell, Ilias Tachtsidis
We present a multi-channel, multi-distance broadband near-infrared spectroscopy (NIRS) system with the capability of measuring changes in haemoglobin concentrations (Δ[HbO2], Δ[HHb]), oxidation state of cytochrome-c-oxidase (Δ[oxCCO]) and tissue oxygen saturation (TOI) in the adult human brain. The main components of the instrument are two customized spectrographs and two light sources. Each spectrograph is lens-based to improve light throughput, has a grating enhanced to optimise reflection in the near-infrared (NIR) spectral region and uses a front illuminated cooled CCD camera (-70° C) with a square chip dimension of 12...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27782703/towards-3d-printed-multifunctional-immobilization-for-proton-therapy-initial-materials-characterization
#17
Steven Michiels, Antoine D'Hollander, Nicolas Lammens, Mathias Kersemans, Guozhi Zhang, Jean-Marc Denis, Kenneth Poels, Edmond Sterpin, Sandra Nuyts, Karin Haustermans, Tom Depuydt
PURPOSE: 3D printing technology is investigated for the purpose of patient immobilization during proton therapy. It potentially enables a merge of patient immobilization, bolus range shifting, and other functions into one single patient-specific structure. In this first step, a set of 3D printed materials is characterized in detail, in terms of structural and radiological properties, elemental composition, directional dependence, and structural changes induced by radiation damage. These data will serve as inputs for the design of 3D printed immobilization structure prototypes...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27746595/evaluation-of-the-flexural-strength-and-microhardness-of-provisional-crown-and-bridge-materials-fabricated-by-different-methods
#18
Shruti Digholkar, V N V Madhav, Jayant Palaskar
PURPOSE: The purpose of this study was to evaluate and compare the flexural strength and microhardness of provisional restorative materials fabricated utilizing rapid prototyping (RP), Computer Assisted Designing and Computer Assisted Milling (CAD-CAM) and conventional method. MATERIALS AND METHODS: Twenty specimens of dimensions 25 mm × 2 mm × 2 mm (ADA-ANSI specification #27) were fabricated each using: (1) Three dimensional (3D) printed light-cured micro-hybrid filled composite by RP resin group, (2) a milled polymethyl methacrylate (CH) using CAD-CAM (CC resin group), and (3) a conventionally fabricated heat activated polymerized CH resin group...
October 2016: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/27718582/all-printed-differential-temperature-sensor-for-the-compensation-of-bending-effects
#19
Shawkat Ali, Arshad Hassan, Jinho Bae, Chong Hyun Lee, Juho Kim
Because printed resistance temperature detectors (RTDs) are affected by tension and compression of metallic patterns on flexible or curved surfaces, a significant temperature-sensing error occurs in general. Hence, we propose a differential temperature sensor (DTS) to compensate the bending effect of the printed RTDs, which is composed of two serially connected similar meander patterns fabricated back-to-back on a polyimide polyethylene terephthalate substrate through a Dimatix DMP-3000 inkjet printer using silver nanoparticles...
November 8, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27662684/design-and-optimization-of-ultrasonic-wireless-power-transmission-links-for-millimeter-sized-biomedical-implants
#20
Miao Meng, Mehdi Kiani
Ultrasound has been recently proposed as an alternative modality for efficient wireless power transmission (WPT) to biomedical implants with millimeter (mm) dimensions. This paper presents the theory and design methodology of ultrasonic WPT links that involve mm-sized receivers (Rx). For given load (RL) and powering distance (d), the optimal geometries of transmitter (Tx) and Rx ultrasonic transducers, including their diameter and thickness, as well as the optimal operation frequency (fc) are found through a recursive design procedure to maximize the power transmission efficiency (PTE)...
February 2017: IEEE Transactions on Biomedical Circuits and Systems
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