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https://www.readbyqxmd.com/read/28738672/physiological-and-physical-responses-to-wearing-compression-garments-during-soccer-matches-and-recovery
#1
Diego Marqués-Jiménez, Julio Calleja-González, Iñaki Arratibel, Anne Delextrat, Fernando Uriarte, Nicolás Terrados
BACKGROUND: There is not enough information on the effects of compression therapy in soccer players during recovery after matches. So the objective of this study was to examine the effect of wearing compression garments during soccer matches and during recovery period on physical responses. METHODS: Eighteen semi-professional soccer players participated in this study. A two-stage crossover design was chosen. Participants acted as controls in one match and were assigned to an experimental group (compression stockings group, full-leg compression group, shorts group) in the other match...
July 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28738671/inertial-flywheel-resistance-training-and-muscle-oxygen-saturation
#2
Rafael Timón, Jesús G Ponce-González, José L González-Montesinos, Guillermo Olcina, Alejandro Pérez-Pérez, José Castro-Piñero
BACKGROUND: The inertial flywheel device causes an increase in eccentric overload during training. The aim was to study muscle oxygen saturation produced during an inertial flywheel squat training, comparing it with a barbell squat training. METHODS: Twelve male adults performed a barbell squat training (3 x 8 reps, 75-80% 1RM) and a flywheel squat training (3 x 8 reps, all-out). Muscle oxygen saturation (%SmO2), total hemoglobin (tHb), reoxygenation, heart rate (HR), lactate, vertical jumps, maximal voluntary isometric contraction and rated perceived exertion (RPE) were studied...
July 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28738542/protective-effects-of-tannic-acid-on-acute-doxorubicin-induced-cardiotoxicity-involvement-of-suppression-in-oxidative-stress-inflammation-and-apoptosis
#3
Jianping Zhang, Lijing Cui, Xue Han, Yuanyuan Zhang, Xuan Zhang, Xi Chu, Fenghua Zhang, Ying Zhang, Li Chu
Doxorubicin (DOX) is a highly effective drug, but its cardiotoxicity restricts its therapeutic index. Oxidative stress is the major etiopathological factor in DOX-induced cardiotoxicity. Tannic acid (TA) has various anti-cancer, antioxidant, and anti-inflammatory activities. The purpose of the study was to survey the possible effects of TA against acute DOX-induced cardiotoxicity. Male Sprague-Dawleyrats were randomly divided into five groups: control, DOX (10mg/kg) alone, DOX with TA (20 and 40mg/kg), or DOX withcaptopril (30mg/kg) treatments...
July 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28738416/conditionally-immortal-slc4a11-mouse-corneal-endothelial-cell-line-recapitulates-disrupted-glutaminolysis-seen-in-slc4a11-mouse-model
#4
Wenlin Zhang, Diego G Ogando, Edward T Kim, Moon-Jung Choi, Hongde Li, Jason M Tenessen, Joseph A Bonanno
Purpose: To establish conditionally immortal mouse corneal endothelial cell lines with genetically matched Slc4a11+/+ and Slc4a11-/- mice as a model for investigating pathology and therapies for SLC4A11 associated congenital hereditary endothelial dystrophy (CHED) and Fuchs' endothelial corneal dystrophy. Methods: We intercrossed H-2Kb-tsA58 mice (Immortomouse) expressing an IFN-γ dependent and temperature-sensitive mutant of the SV40 large T antigen (tsTAg) with Slc4a11+/+ and Slc4a11-/- C57BL/6 mice...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28738246/crocin-modulates-il-4-il-13-signaling-and-ameliorates-experimentally-induced-allergic-airway-asthma-in-a-murine-model
#5
Haidy Yosri, Wagdi F Elkashef, Eman Said, Nariman M Gameil
Allergic asthma is a chronic respiratory disease with a prevalent T helper (Th2)-mediated immune reaction. Crocin, the major bioactive constituent of saffron, has been reported in multiple studies to have numerous pharmacological activities, including prominent anti-oxidant activities. In the current study, the anti-asthmatic potential of crocin was evaluated. Adult male Swiss Albino mice were administered 10mg of ovalbumin (OVA) mixed with 1mg of aluminum hydroxide intraperitoneally on days 0 and 7 and were administered crocin (25mg/kg) orally daily for 16days...
July 21, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28737589/validity-of-a-taekwondo-specific-test-to-measure-vo2peak-and-the-heart-rate-deflection-point
#6
Jader Sant'Ana, Emerson Franchini, Juan Murias, Fernando Diefenthaeler
This study investigated whether the progressive specific taekwondo test (PSTT) is a valid test to measure peak oxygen consumption (VO2PEAK) and the heart rate deflection point (HRDP) in taekwondo athletes. Eighteen male black belt athletes (25.3 ± 4.8 years; 8.2 ± 4.7 years of practice; 171.8 ± 4.7 cm; 76.1 ± 8.2 kg, and 13.1 ± 2.9% body fat) involved in regional and national level competitions performed the PSTT and an incremental treadmill test (IT). The following variables were analyzed: VO2PEAK, respiratory quotient, oxygen consumption at the HRDP (VO2HRDP), peak heart rate (HRPEAK), HRDP, and peak post-test blood lactate concentration...
July 19, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28737586/comparison-of-acute-physiological-and-psychological-responses-between-moderate-intensity-continuous-exercise-and-three-regimes-of-high-intensity-training
#7
Nicole Green, Timothy Wertz, Zachary LaPorta, Adam Mora, Jasmine Serbas, Todd A Astorino
High intensity interval training (HIIT) elicits similar physiological adaptations as moderate intensity continuous training (MICT) despite less time commitment. However, there is debate whether HIIT is more aversive than MICT. This study compared physiological and perceptual responses between MICT and three regimes of HIIT. Nineteen active adults (age = 24.0 ± 3.3 yr) unfamiliar with HIIT initially performed ramp exercise to exhaustion to measure maximal oxygen uptake (VO2 max) and determine workload for subsequent sessions, whose order was randomized...
July 19, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28737429/hif-1%C3%AE-inhibition-by-diethylstilbestrol-and-its-polyacetal-conjugate-in-hypoxic-prostate-tumour-cells-insights-from-nmr-metabolomics
#8
Ana Armiñán, Luís Mendes, Joana Carrola, Julie Movellan, María J Vicent, Iola F Duarte
In this study, we have employed (1)H NMR metabolomics to assess the metabolic responses of PC3 prostate tumour cells to hypoxia and to pharmacological HIF-1α inhibition by DES or its polyacetal conjugate tert-DES. Oxygen deprivation prompted a number of changes in intracellular composition and metabolic activity, mainly reflecting upregulated glycolysis, amino acid catabolism and other compensatory mechanisms used by hypoxic cells to deal with oxidative imbalance and energy deficit. Cell treatment with a non-cytotoxic concentration of DES, under hypoxia, triggered significant changes in 17 metabolites...
July 24, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28737209/lactate-dehydrogenase-as-a-prognostic-marker-in-al-amyloidosis-expected-or-unexpected
#9
EDITORIAL
Chor S Chim
No abstract text is available yet for this article.
July 24, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28736511/effects-of-methylsulfonylmethane-msm-on-exercise-induced-oxidative-stress-muscle-damage-and-pain-following-a-half-marathon-a-double-blind-randomized-placebo-controlled-trial
#10
Eric D Withee, Kimberly M Tippens, Regina Dehen, Deanne Tibbitts, Douglas Hanes, Heather Zwickey
BACKGROUND: Oxidative stress and muscle damage occur during exhaustive bouts of exercise, and many runners report pain and soreness as major influences on changes or breaks in training regimens, creating a barrier to training persistence. Methylsulfonylmethane (MSM) is a sulfur-based nutritional supplement that is purported to have pain and inflammation-reducing effects. To investigate the effects of MSM in attenuating damage associated with physical exertion, this randomized, double-blind, placebo-controlled study evaluated the effects of MSM supplementation on exercise-induced pain, oxidative stress and muscle damage...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28736173/low-doses-of-17%C3%AE-ethinyl-estradiol-alter-the-maternal-brain-and-induce-stereotypies-in-cd-1-mice-exposed-during-pregnancy-and-lactation
#11
Mary C Catanese, Laura N Vandenberg
Maternal care is critical for the survival, development and long-term success of offspring. Despite our current understanding of the role of endogenous estrogen in both maternal behavior and the maternal brain, the potential effects of exogenous estrogens on these endpoints remain poorly understood. Here, pregnant CD-1 mice were exposed to low doses of 17α-ethinyl estradiol (EE2), commonly used as a positive control in studies of other xenoestrogens, from day 9 of pregnancy until weaning. Using traditional maternal behavior assays, we document no significant changes in maternal behavior throughout the lactational period...
July 20, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28736119/close-correlation-between-arterial-and-central-venous-lactate-concentrations-of-children-in-shock-a-cross-sectional-study
#12
Suwannee Phumeetham, Nujaree Kaowchaweerattanachart, Suvikrom Law, Prakul Chanthong, Busadee Pratumvinit
BACKGROUND: Arterial lactate (aLact) has been widely used to guide therapeutic decisions in children with shock. We evaluated the feasibility of central venous lactate (cvLact) in assessing aLact among children with shock. METHODS: Pairs of arterial and central venous samples for lactate concentrations were collected simultaneously during the shock and hemodynamically stable states. The results were analyzed by using a Cobas 8000 analyzer. RESULTS: Sixty-four blood paired samples were collected from 48 patients...
July 20, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28736085/low-cardiac-output-syndrome-in-the-postoperative-period-of-cardiac-surgery-profile-differences-in-clinical-course-and-prognosis-the-esbaga-study
#13
J L Pérez Vela, J J Jiménez Rivera, M Á Alcalá Llorente, B González de Marcos, H Torrado, C García Laborda, M D Fernández Zamora, F J González Fernández, J C Martín Benítez
OBJECTIVES: An analysis is made of the clinical profile, evolution and differences in morbidity and mortality of low cardiac output syndrome (LCOS) in the postoperative period of cardiac surgery, according to the 3 diagnostic subgroups defined by the SEMICYUC Consensus 2012. DESIGN: A multicenter, prospective cohort study was carried out. SETTING: ICUs of Spanish hospitals with cardiac surgery. PATIENTS: A consecutive sample of 2,070 cardiac surgery patients was included, with the analysis of 137 patients with LCOS...
July 20, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28736054/low-sensitivity-of-anion-gap-to-detect-clinically-significant-lactic-acidosis-in-the-emergency-department
#14
Q Xu, S HowlettClyne, A Fuezery, G S Cembrowski
INTRODUCTION: Lactic acidosis represents the pathologic accumulation of lactate and hydrogen ions. It is important to efficiently diagnose lactic acidosis as delayed treatment will lead to poor patient outcomes. As plasma lactate levels may not be rapidly available, some physicians may use elevated anion gaps to test for the need to measure lactate. All Edmonton metropolitan hospitals have Radiometer blood gas/electrolyte instruments in the ED or close by. As lactate is measured for each set of electrolytes, we were able to determine the effectiveness of a screening anion gap for lactic acidosis...
July 20, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28735600/evidence-for-increasing-digestive-and-metabolic-efficiency-of-energy-utilization-with-age-of-dairy-cattle-as-determined-in-two-feeding-regimes
#15
F Grandl, J O Zeitz, M Clauss, M Furger, M Kreuzer, A Schwarm
The changes taking place with age in energy turnover of dairy cattle are largely unknown. It is unclear whether the efficiency of energy utilization in digestion (characterized by faecal and methane energy losses) and in metabolism (characterized by urine and heat energy losses) is altered with age. In the present study, energy balance data were obtained from 30 lactating Brown Swiss dairy cows aged between 2 and 10 years, and 12 heifers from 0.5 to 2 years of age. In order to evaluate a possible dependence of age effects on diet type, half of the cattle each originated from two herds kept at the same farm, which were fed either on a forage-only diet or on the same forage diet but complemented with 5 kg/day of concentrate since their first calving...
July 24, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28735466/comparative-metabolic-analysis-in-head-and-neck-cancer-and-the-normal-gingiva
#16
Nadine Fabienne Voelxen, Sebastian Blatt, Pascal Knopf, Maurice Henkel, Christina Appelhans, Leonardo A R Righesso, Andreas Pabst, Jutta Goldschmitt, Stefan Walenta, Andreas Neff, Wolfgang Mueller-Klieser, Thomas Ziebart
OBJECTIVES: Chronic accumulation of lactate in malignant tumor tissue is associated with increased malignancy and radioresistance. For this study, biopsies of primary head and neck squamous cell carcinoma (HNSCC) and of the normal gingiva of the same patient were compared via metabolic profiling to the healthy gingiva from cancer-free patients. MATERIALS AND METHODS: Cryobiopsies of 140 HNSCC patients were used to determine ATP, lactate, and glucose concentrations of the tumor and normal gingiva via induced metabolic bioluminescence imaging (imBI)...
July 22, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28735321/betaine-improves-polymer-grade-d-lactic-acid-production-by-sporolactobacillus-inulinus-using-ammonia-as-green-neutralizer
#17
Guoping Lv, Chengchuan Che, Li Li, Shujing Xu, Wanyi Guan, Baohua Zhao, Jiansong Ju
The traditional CaCO3-based fermentation process generates huge amount of insoluble CaSO4 waste. To solve this problem, we have developed an efficient and green D-lactic acid fermentation process by using ammonia as neutralizer. The 106.7 g/L of D-lactic acid production and 0.89 g per g of consumed sugar were obtained by Sporolactobacillus inulinus CASD with a high optical purity of 99.7% by adding 100 mg/L betaine in the simple batch fermentation process. The addition of betaine was experimentally proven to protect cell at high concentration of ammonium ion, increase the D-lactate dehydrogenase specific activity and thus promote the production of D-lactic acid...
July 6, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/28735042/improved-selectivity-and-cytotoxic-effects-of-irinotecan-via-liposomal-delivery-a-comparative-study-on-hs68-and-hela-cells
#18
Ana Casadó, Margarita Mora, M Lluïsa Sagristá, Santi Rello-Varona, Pilar Acedo, Juan Carlos Stockert, Magdalena Cañete, Angeles Villanueva
Irinotecan (CPT-11) is an effective chemotherapeutic agent widely used to treat different cancers. Otherwise, the liposomal delivery of anti-tumor agents has been shown to be a promising strategy. The aim of this study has been to analyze the effect of liposomal CPT-11 (CPT-11lip) on two human cell lines (Hs68 and HeLa) to establish the suitability of this CPT-11 nanocarrier. We have demonstrated the highest uptake of CPT-11lip in comparison with that of CPT-11sol, in lactate buffer, and that CPT-11lip was internalized in the cells through an endocytic process whereas CPT-11sol does so by passive diffusion...
July 19, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28734854/pulse-pressure-variation-as-a-guide-for-volume-expansion-in-dogs-undergoing-orthopedic-surgery
#19
Denise T Fantoni, Keila K Ida, André M Gimenes, Matheus M Mantovani, Jacqueline R Castro, Geni C F Patrício, Aline M Ambrósio, Denise A Otsuki
OBJECTIVE: To investigate whether pulse pressure variation (PPV) can predict fluid responsiveness in healthy dogs during clinical surgery. STUDY DESIGN: Prospective clinical study. ANIMALS: Thirty-three isoflurane-anesthetized dogs with arterial hypotension during orthopedic surgery. METHODS: Fluid challenge with lactated Ringer's solution (15 mL kg(-1) in 15 minutes) was administered in mechanically ventilated dogs (tidal volume 10 mL kg(-1)) with hypotension [mean arterial pressure (MAP) < 65 mmHg]...
March 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28734739/serum-levels-of-squamous-cell-carcinoma-antigens-1-and-2-reflect-disease-severity-and-clinical-type-of-atopic-dermatitis-in-adult-patients
#20
Tomoko Okawa, Yukie Yamaguchi, Kenzen Kou, Junya Ono, Yoshinori Azuma, Noriko Komitsu, Yusuke Inoue, Masumi Kohno, Setsuko Matsukura, Takeshi Kambara, Shoichiro Ohta, Kenji Izuhara, Michiko Aihara
BACKGROUND: Recent studies have indicated that serum levels of squamous cell carcinoma antigen (SCCA) 1 and 2 induced by type 2 cytokines such as IL-4 and IL-13, are increased in patients with atopic dermatitis (AD). However, no clinical studies have analyzed serum levels of SCCA2 in larger series of AD patients or their association with various clinical characteristics. This study was performed to clarify whether serum levels of SCCA2 are associated with disease severity and clinical phenotypes of adult AD patients...
July 19, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
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