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Liver ultrasound

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https://www.readbyqxmd.com/read/29774454/analysis-of-three-ultrasound-elastography-techniques-for-grading-liver-fibrosis-in-patients-with-chronic-hepatitis-b
#1
Xinping Ren, Shujun Xia, Zhongxin Ni, Weiwei Zhan, Jianqiao Zhou
BACKGROUND: Evaluation of liver fibrosis is important to assess prognosis and guide the treatment for chronic hepatitis B. OBJECTIVE: To analyze and compare transient, point, and two-dimensional (2D) shear wave elastography techniques in grading the liver fibrosis. METHODS: Based on the severity of liver inflammation and fibrosis (Scheuer criteria), 158 patients with chronic hepatitis B were assigned into group 1 (either G or S classification < 2) or group 2 (either G or S classification ≥ 2)...
May 17, 2018: La Radiologia Medica
https://www.readbyqxmd.com/read/29770228/acoustic-radiation-force-impulse-arfi-elastography-in-a-cohort-of-alpha-1-antitrypsin-deficient-individuals-and-healthy-volunteers
#2
Sandra Diaz, Behrouz Mostafavi, Hanan A Tanash, Eeva Piitulainen
Background: Acoustic radiation force impulse (ARFI) elastography has been used to assess liver stiffness non-invasively. However, its usefulness in alpha-1 antitripsin-deficient (AATD) individuals is unknown. Purpose: To assess if liver fibrosis is present in a cohort of AATD individuals using ARFI elastography. Material and Methods: Eighty-three participants aged 38-39 years, except for two who were aged 40 years, underwent ultrasound elastography of the liver with ARFI technique...
April 2018: Acta Radiologica Open
https://www.readbyqxmd.com/read/29769030/in-silico-simulation-of-liver-crack-detection-using-ultrasonic-shear-wave-imaging
#3
Erwei Nie, Jiao Yu, Debaditya Dutta, Yanying Zhu
BACKGROUND: Liver trauma is an important source of morbidity and mortality worldwide. A timely detection and precise evaluation of traumatic liver injury and the bleeding site is necessary. There is a need to develop better imaging modalities of hepatic injuries to increase the sensitivity of ultrasonic imaging techniques for sites of hemorrhage caused by cracks. In this study, we conduct an in silico simulation of liver crack detection and delineation using an ultrasonic shear wave imaging (USWI) based method...
May 16, 2018: BMC Medical Imaging
https://www.readbyqxmd.com/read/29764827/not-so-mass-effect-finding-of-a-remarkable-incidentaloma-in-a-teenager-with-neurofibromatosis
#4
Daniel John Keen, Hannah Norman-Bruce, Salah Mansy
A 13-year-old boy with neurofibromatosis type 1 presented to the emergency department twice in a fortnight with moderate intermittent abdominal pain, radiating to the back and associated with nausea and vomiting. He examined as a well child with a soft abdomen and minimal tenderness. A history of constipation was identified but he failed to respond to a trial of laxatives. Subsequent ultrasound abdomen demonstrated a large mass surrounding the porta hepatis. MRI further characterised a focal, non-aggressive lesion extending from his liver, encapsulating his pancreas, portal vessels and laterally displacing his spleen and left kidney...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29764258/reference-less-mr-thermometry-on-pre-clinical-thiel-human-cadaver-for-liver-surgery-with-mrgfus
#5
Ioannis Karakitsios, Senay Mihcin, Andreas Melzer
PURPOSE: Reference-less MR thermometry can be a promising technique for temperature mapping during liver treatment with Magnetic Resonance-guided Focused Ultrasound (MRgFUS), as it is more robust to breathing motion than Proton Resonance Frequency MR thermometry. However, there is a lack of a pre-clinical model for repeatable testing of reference-less thermometry. The purpose of this work was to verify the explanted Thiel embalmed human liver and whole Thiel embalmed human cadaver for application of a custom made reference-less thermometry algorithm during MRgFUS sonication...
May 15, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29761535/diagnostic-performance-of-shear-wave-elastography-in-patients-with-autoimmune-liver-disease
#6
Changtian Li, Manish Dhyani, Atul K Bhan, Joseph R Grajo, Daniel S Pratt, Michael S Gee, Anthony E Samir
OBJECTIVES: To assess performance of shear wave elastography for evaluation of fibrosis and the histologic stage in patients with autoimmune liver disease (ALD) and to validate previously established advanced fibrosis cutoff values in this cohort. METHODS: Shear wave elastography was performed on patients with ALD with an Aixplorer ultrasound system (SuperSonic Imagine, Aix-en-Provence, France) using an SC6-1 transducer. The median estimated tissue Young modulus was calculated from sets of 8 to 10 elastograms...
May 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29761521/negative-predictive-value-of-contrast-enhanced-ultrasound-in-differentiating-avascular-solid-appearing-from-vascularized-masses-a-retrospective-consecutive-study
#7
Abdulmohsen Alrashed, Hassan Ahmad, Korosh Khalili, Tae Kyoung Kim, Huynh-Jung Jang, Mostafa Atri
OBJECTIVES: To determine the negative predictive value (NPV) of contrast-enhanced ultrasound (CEUS) to establish the lack of vascularity in a mass. METHODS: This work was an Institutional Review Board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study. Acquisition of consent was waived. We included all CEUS examinations performed for tissue characterization between 2004 and 2014 that reported showing no vascularity in a mass...
May 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29760679/hematocrit-values-predict-carotid-intimal-media-thickness-in-obese-patients-with-non-alcoholic-fatty-liver-disease-a-cross-sectional-study
#8
Giovanni Tarantino, Luigi Barrea, Domenico Capone, Vincenzo Citro, Teresa Mosca, Silvia Savastano
Background: Literature data suggest with some criticism that full-fledged cardiovascular (CV) events (acute or chronic) are likely predicted by blood components, which are reported to be associated with the presence/severity of non-alcoholic fatty liver disease (NAFLD). This study was aimed at determining which marker(s) derived from blood count, such as white blood cells, neutrophils, neutrophil/lymphocyte ratio, platelet count, hemoglobin, mean corpuscular volume, hematocrit values were associated with ear or subclinical atherosclerosis, in obese patients of various classes suffering from NAFLD...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29760403/correlation-between-ultrasound-diagnosed-non-alcoholic-fatty-liver-and-periodontal-condition-in-a-cross-sectional-study-in-japan
#9
Takahiro Iwasaki, Akiko Hirose, Tetsuji Azuma, Tamie Ohashi, Kazutoshi Watanabe, Akihiro Obora, Fumiko Deguchi, Takao Kojima, Atsunori Isozaki, Takaaki Tomofuji
This cross-sectional study investigated the relationship between periodontal condition and ultrasound-diagnosed non-alcoholic fatty liver disease (NAFLD) in a Japanese oral health check population. A total of 1226 consecutive participant were enrolled in the study. Abdominal ultrasonography was applied to diagnose NAFLD. Of the study participants, 339 (27.7%) had ultrasonography-diagnosed NAFLD. The participants with NAFLD had a significantly higher prevalence of probing pocket depth (PPD) ≥ 4 mm (86...
May 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29759425/simultaneous-evaluation-of-thermal-and-non-thermal-effects-of-high-intensity-focused-ultrasound-on-a-tissue-mimicking-phantom
#10
Yong Tae Kim, Donghee Ma, Jai Kyoung Sim, Se-Hwa Kim
Physiologically relevant phantoms with high reliability are essential for extending the therapeutic applications of high-intensity therapeutic ultrasound. Here we describe a tissue-mimicking phantom capable of quantifying temperature changes and observing non-thermal phenomena by high-intensity therapeutic ultrasound. Using polydiacetylene liposomes, we fabricated agar-based polydiacetylene hydrogel phantoms (PHPs) that not only respond to temperature, but also have acoustic properties similar to those of human liver tissue...
May 11, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29758936/evaluation-of-integrated-color-coded-perfusion-analysis-for-contrast-enhanced-ultrasound-ceus-after-percutaneous-interventions-for-malignant-liver-lesions-first-results
#11
I Wiesinger, L P Beyer, N Zausig, N Verloh, P Wiggermann, C Stroszczynski, E M Jung
BACKGROUND:  With the rising number of percutaneous ablation therapies in malignant liver lesions there is a need of reliable diagnostics after the intervention to differentiate between reactive changes and tumor. PURPOSE: To assess the success of percutaneous ablation therapies for malignant liver lesions using CEUS with perfusion analysis. MATERIAL AND METHODS: Retrospective analysis of perfusion analysis for 67 patients with 94 malignant liver lesions, treated with ablation therapies...
2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29755902/efficacy-and-safety-of-wheat-grass-in-thalassemic-children-on-regular-blood-transfusion
#12
Amit S Mutha, Kalpana U Shah, Aarti A Kinikar, Balasaheb B Ghongane
BACKGROUND: In thalassemia, mutations either in alpha or beta chain synthesis results in low hemoglobin (Hb). Wheatgrass has been used for many years for health purposes. Some reports suggest the beneficial effect of wheatgrass on transfusion requirements. Folic acid is also known to play an important role in several biochemical reactions. In some patients with thalassemia, the supplementation of folic acid is useful. OBJECTIVE: To evaluate the efficacy and safety of wheatgrass in children with thalassemia receiving chronic blood transfusions...
March 11, 2018: Curēus
https://www.readbyqxmd.com/read/29754940/radioguided-hepatic-resection-with-18-f-dopa-in-a-patient-with-metastatic-medullary-thyroid-carcinoma
#13
J López-Gómez, S Medina-Ornelas, M A Salazar-Álvarez, M Álvarez-Bojórquez, N Zaragoza-Cruz, J Melchor-Ruan, A Álvarez-Cano
INTRODUCTION: Medullary carcinoma accounts for 1-2% of all thyroid malignancies. 13-20% of patients present with distant metastasis, with 45% of the cases affecting the liver. CLINICAL CASE: A 50-year-old woman, diagnosed with medullary thyroid carcinoma, was treated with total thyroidectomy and a modified neck dissection in 1999. Two lymph node recurrences in the neck were treated with surgical resection; during surveillance, she developed elevated calcitonin levels, the recurrence site was identified with 18 F-DOPA PET/CT in the liver...
May 10, 2018: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29753526/prenatally-versus-postnatally-diagnosed-congenital-diaphragmatic-hernia-side-stage-and-outcome
#14
Carmen Mesas Burgos, Björn Frenckner, Matias Luco, Matthew T Harting, Pamela A Lally, Kevin P Lally
AIM: To compare outcomes between prenatally and postnatally diagnosed CDH in a large multicenter database of prospectively collected data and evaluate factors associated with poorer outcome for prenatally diagnosed CDH. MATERIAL AND METHODS: We used information from the multicenter, multinational CDH Study Group database on patients born between 2007 and 2015. We compared differences between prenatally and postnatally diagnosed CDH with respect to survival, side, size, ECMO needs, associated major cardiac malformations and liver position...
April 14, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29752712/maternal-diabetes-alters-the-development-of-ductus-venosus-shunting-in-the-fetus
#15
Agnethe Lund, Cathrine Ebbing, Svein Rasmussen, Torvid W Kiserud, Jörg Kessler
INTRODUCTION: Despite adequate glycemic control, the risks of fetal macrosomia and perinatal complications are increased in diabetic pregnancies. Adjustments of the umbilical venous (UV) distribution, including increased ductus venosus (DV) shunting, can be important fetal compensatory mechanisms, but the impact of pregestational diabetes on UV and DV flow is not known. MATERIAL AND METHODS: In this prospective study, 49 women with pregestational diabetes mellitus underwent monthly ultrasound examinations from gestational week 20 to 36...
May 11, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29749323/effects-of-delta-tocotrienol-supplementation-on-liver-enzymes-inflammation-oxidative-stress-and-hepatic-steatosis-in-patients-with-nonalcoholic-fatty-liver-disease
#16
Muhammad Amjad Pervez, Dishad Ahmet Khan, Aamir Ijaz, Shamrez Khan
BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem worldwide and is associated with increased morbidity and mortality. Currently, there is no definitive treatment for this disease. δ-Tocotrienol has potent anti-inflammatory and antioxidant properties and may reduce liver injury in NAFLD. The present study aims to evaluate the efficacy and safety of δ-tocotrienol in the treatment of NAFLD. MATERIALS AND METHODS: The present study was a randomized, double-blind, placebo-controlled pilot study conducted in patients aged > 20 years, belonging to both sexes, having ultrasound-proven fatty liver disease, having a fatty liver index (FLI) of ≥ 60, and persistent elevation of alanine transaminase...
March 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29743740/evaluation-of-the-fetal-abdomen-by-magnetic-resonance-imaging-part-1-malformations-of-the-abdominal-cavity
#17
Ana Paula Pinho Matos, Luciana de Barros Duarte, Pedro Teixeira Castro, Pedro Daltro, Heron Werner Júnior, Edward Araujo Júnior
Although ultrasound continues to be the mainstay modality for the evaluation of fetal disorders, fetal magnetic resonance imaging (MRI) has often been used as a valuable adjunct in recent years. The exponential growth of the use of fetal MRI has been facilitated by technological advancements such as ultrafast T2-weighted sequences and diffusion-weighted imaging. Fetal MRI can achieve results that are comparable to or better than those of ultrasound, particularly in cases of maternal obesity, severe oligohydramnios, or abnormal fetal position...
March 2018: Radiologia Brasileira
https://www.readbyqxmd.com/read/29742707/surgical-treatment-for-metastasis-from-lymphoepithelioma-like-cholangiocarcinoma-in-the-liver-a-case-report
#18
Jun-Wei Zhang, Hua-Yu Yang, Yi-Yao Xu, Xin-Ting Sang, Shuang-Ni Yu, Han-Chun Huang, Jin Bian, Jian-Ping Xiong, Xin Lu
RATIONALE: Lymphoepithelioma-like cholangiocarcinoma (LEL-CC) is a rare variant of intrahepatic cholangiocarcinoma (ICC), which is characterized by the better outcome than normal ICC. There is no report about the treatment for the metastasis of the LEL-CC. Here, we describe a rare case of LEL-CC of the liver and report the treatment for metastasis of it. PATIENT CONCERNS: A 38-year-old woman with a chronic hepatitis B infection was referred to the department of liver surgery in our hospital with a mass in the liver...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29742700/characteristics-and-management-of-pyogenic-liver-abscess-a-european-experience
#19
Cristina Serraino, Chiara Elia, Christian Bracco, Gianluca Rinaldi, Fulvio Pomero, Alberto Silvestri, Remo Melchio, Luigi Maria Fenoglio
Pyogenic liver abscess (PLA) are space-occupying lesions in the liver associated with high morbidity and mortality. The aim of this study is to review an Italian hospital experience in epidemiological, clinical patterns, and management of PLA.We performed a retrospective, descriptive case series at a single center assessing demographic characteristics, presentation patterns, etiological factors, microbiological etiology, and management for patients treated for PLA between 2000 and 2016.Around 109 patients were identified...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29740437/targeting-and-therapy-of-glioblastoma-in-a-mouse-model-using-exosomes-derived-from-natural-killer-cells
#20
Liya Zhu, Ji Min Oh, Prakash Gangadaran, Senthilkumar Kalimuthu, Se Hwan Baek, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn
Objective: Glioblastoma is a highly aggressive primary brain tumor that is resistant to radiotherapy and chemotherapy. Natural killer (NK) cells have been used to treat incurable cancers. Recent studies have investigated the effectiveness of NK-cell-derived exosomes (NK-Exo) for treating incurable cancers such as melanoma, leukemia, and neuroblastoma; however, NK-Exo have not been used to treat glioblastoma. In the present study, we investigated the antitumor effects of NK-Exo against aggressive glioblastoma both in vitro and in vivo and determined the tumor-targeting ability of NK-Exo by performing fluorescence imaging...
2018: Frontiers in Immunology
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