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Water fat imaging

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https://www.readbyqxmd.com/read/28342191/exploiting-multicompartment-effects-in-triple-echo-steady-state-t2-mapping-for-fat-fraction-quantification
#1
Dian Liu, Andreas Steingoetter, Jelena Curcic, Sebastian Kozerke
PURPOSE: To investigate and exploit the effect of intravoxel off-resonance compartments in the triple-echo steady-state (TESS) sequence without fat suppression for T2 mapping and to leverage the results for fat fraction quantification. METHODS: In multicompartment tissue, where at least one compartment is excited off-resonance, the total signal exhibits periodic modulations as a function of echo time (TE). Simulated multicompartment TESS signals were synthesized at various TEs...
March 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28341872/childhood-adversity-associated-with-white-matter-alteration-in-the-corpus-callosum-corona-radiata-and-uncinate-fasciculus-of-psychiatrically-healthy-adults
#2
Simon McCarthy-Jones, Lena K L Oestreich, Amanda E Lyall, Zora Kikinis, Dominick T Newell, Peter Savadjiev, Martha E Shenton, Marek Kubicki, Ofer Pasternak, Thomas J Whitford
Diffusion tensor imaging studies report childhood adversity (CA) is associated with reduced fractional anisotropy (FA) in multiple white matter tracts in adults. Reduced FA may result from changes in tissue, suggesting myelin/axonal damage, and/or from increased levels of extracellular free-water, suggesting atrophy or neuroinflammation. Free-water imaging can separately identify FA in tissue (FAT) and the fractional volume of free-water (FW). We tested whether CA was associated with altered FA, FAT, and FW in seven white matter regions of interest (ROI), in which FA changes had been previously linked to CA (corona radiata, corpus callosum, fornix, cingulum bundle: hippocampal projection, inferior fronto-occipital fasciculus, superior longitudinal fasciculus, uncinate fasciculus)...
March 25, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28324157/water-fat-mri-in-a-hibernator-reveals-seasonal-growth-of-white-and-brown-adipose-tissue-without-cold-exposure
#3
Amanda MacCannell, Kevin Sinclair, Lannette Friesen-Waldner, Charles A McKenzie, James F Staples
Obligate hibernators, such as ground squirrels, display circannual patterns which persist even under constant laboratory conditions, suggesting that they are regulated by endogenous rhythms. Brown adipose tissue (BAT) is important for thermogenesis during periodic arousals from hibernation when core body temperature rises spontaneously from 5 to 37 °C. In most small eutherians BAT growth requires several weeks of cold exposure. We hypothesized that in the thirteen-lined ground squirrel (Ictidomys tridecemlineatus), a hibernator, BAT growth is regulated, in part, by an endogenous rhythm and we predicted that this growth would precede the hibernation season without cold exposure...
March 21, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28306547/synthetic-ct-for-mri-based-liver-stereotactic-body-radiotherapy-treatment-planning
#4
Jeremy S Bredfeldt, Lianli Liu, Mary Feng, Yue Cao, James M Balter
A technique for generating MRI-derived synthetic CT volumes (MRCTs) is demonstrated in support of adaptive liver stereotactic body radiation therapy (SBRT). Under IRB approval, 16 subjects with hepatocellular carcinoma were scanned using a single MR pulse sequence (T1 Dixon). Air-containing voxels were identified by intensity thresholding on T1-weighted, water and fat images. The envelope of the anterior vertebral bodies was segmented from the fat image and fuzzy-C-means (FCM) was used to classify each non-air voxel as mid-density, lower-density, bone, or marrow in the abdomen, with only bone and marrow classified within the vertebral body envelope...
March 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28278002/quantifying-abdominal-adipose-tissue-and-thigh-muscle-volume-and-hepatic-proton-density-fat-fraction-repeatability-and-accuracy-of-an-mr-imaging-based-semiautomated-analysis-method
#5
Michael S Middleton, William Haufe, Jonathan Hooker, Magnus Borga, Olof Dahlqvist Leinhard, Thobias Romu, Patrik Tunón, Gavin Hamilton, Tanya Wolfson, Anthony Gamst, Rohit Loomba, Claude B Sirlin
Purpose To determine the repeatability and accuracy of a commercially available magnetic resonance (MR) imaging-based, semiautomated method to quantify abdominal adipose tissue and thigh muscle volume and hepatic proton density fat fraction (PDFF). Materials and Methods This prospective study was institutional review board- approved and HIPAA compliant. All subjects provided written informed consent. Inclusion criteria were age of 18 years or older and willingness to participate. The exclusion criterion was contraindication to MR imaging...
March 9, 2017: Radiology
https://www.readbyqxmd.com/read/28275542/parkinson-s-disease-diffusion-mri-is-not-affected-by-acute-antiparkinsonian-medication
#6
Jae Woo Chung, Roxana G Burciu, Edward Ofori, Priyank Shukla, Michael S Okun, Christopher W Hess, David E Vaillancourt
OBJECTIVE: A prior longitudinal study demonstrates that free-water diffusion magnetic resonance imaging (dMRI) tracks progression in the substantia nigra (Ofori et al., 2015b). Here, we test the acute effects of antiparkinsonian medication on this established imaging progression marker for the first time. METHODS: Fifteen PD patients underwent dMRI OFF and ON-medication one day apart. ON-medication, patients were tested approximately 45 min after their usual dose of antiparkinsonian medication...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28263827/a-fast-method-for-the-quantification-of-fat-fraction-and-relaxation-times-comparison-of-five-sites-of-bone-marrow
#7
Caroline Le Ster, Jérémy Lasbleiz, Stephan Kannengiesser, Raphaël Guillin, Giulio Gambarota, Hervé Saint-Jalmes
PURPOSE: Bone marrow is found either as red bone marrow, which mainly contains haematopoietic cells, or yellow bone marrow, which mainly contains adipocytes. In adults, red bone marrow is principally located in the axial skeleton. A recent study has introduced a method to simultaneously estimate the fat fraction (FF), the T1 and T2* relaxation times of water (T1w, T2*w) and fat (T1f and T2*f) in the vertebral bone marrow. The aim of the current study was to measure FF, T1w, T1f, T2*w and T2*f in five sites of bone marrow, and to assess the presence of regional variations...
March 2, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28263425/fast-bilateral-breast-coverage-with-high-spectral-and-spatial-resolution-hiss-mri-at-3t
#8
Milica Medved, Hui Li, Hiroyuki Abe, Deepa Sheth, Gillian M Newstead, Olufunmilayo I Olopade, Maryellen L Giger, Gregory S Karczmar
PURPOSE: To develop and assess a full-coverage, sensitivity encoding (SENSE)-accelerated breast high spatial and spectral resolution (HiSS) magnetic resonance imaging (MRI) within clinically reasonable times as a potential nonenhanced MRI protocol for breast density measurement or breast cancer screening. MATERIALS AND METHODS: Sixteen women with biopsy-proven cancer or suspicious lesions, and 13 women who were healthy volunteers or were screened for breast cancer, received 3T breast MRI exams, including SENSE-accelerated HiSS MRI, which was implemented as a submillimeter spatial resolution echo-planar spectroscopic imaging (EPSI) sequence...
March 6, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28247430/a-novel-phase-unwrapping-method-based-on-pixel-clustering-and-local-surface-fitting-with-application-to-dixon-water-fat-mri
#9
Junying Cheng, Yingjie Mei, Biaoshui Liu, Jijing Guan, Xiaoyun Liu, Ed X Wu, Qianjin Feng, Wufan Chen, Yanqiu Feng
PURPOSE: To develop and evaluate a novel 2D phase-unwrapping method that works robustly in the presence of severe noise, rapid phase changes, and disconnected regions. THEORY AND METHODS: The MR phase map usually varies rapidly in regions adjacent to wraps. In contrast, the phasors can vary slowly, especially in regions distant from tissue boundaries. Based on this observation, this paper develops a phase-unwrapping method by using a pixel clustering and local surface fitting (CLOSE) approach to exploit different local variation characteristics between the phase and phasor data...
March 1, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28244504/ambulatory-function-in-motor-incomplete-spinal-cord-injury-a-magnetic-resonance-imaging-study-of-spinal-cord-edema-and-lower-extremity-muscle-morphometry
#10
A C Smith, K A Weber, T B Parrish, T G Hornby, V M Tysseling, J G McPherson, M Wasielewski, J M Elliott
STUDY DESIGN: This research utilized a cross-sectional design. OBJECTIVES: Spinal cord edema length has been measured with T2-weighted sagittal MRI to predict motor recovery following spinal cord injury. The purpose of our study was to establish the correlational value of axial spinal cord edema using T2-weighted MRI. We hypothesized a direct relationship between the size of damage on axial MRI and walking ability, motor function and distal muscle changes seen in motor incomplete spinal cord injury (iSCI)...
February 28, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28241015/a-concept-for-holistic-whole-body-mri-data-analysis-imiomics
#11
Robin Strand, Filip Malmberg, Lars Johansson, Lars Lind, Magnus Sundbom, Håkan Ahlström, Joel Kullberg
PURPOSE: To present and evaluate a whole-body image analysis concept, Imiomics (imaging-omics) and an image registration method that enables Imiomics analyses by deforming all image data to a common coordinate system, so that the information in each voxel can be compared between persons or within a person over time and integrated with non-imaging data. METHODS: The presented image registration method utilizes relative elasticity constraints of different tissue obtained from whole-body water-fat MRI...
2017: PloS One
https://www.readbyqxmd.com/read/28238449/the-feasibility-of-semi-automatically-generated-red-bone-marrow-segmentations-based-on-mr-only-for-patients-with-gynecologic-cancer
#12
Anna Andreychenko, Petra S Kroon, Matteo Maspero, Ina Jürgenliemk-Schulz, Astrid A C De Leeuw, Marnix G E H Lam, Jan J W Lagendijk, Cornelis A T van den Berg
PURPOSE: For patients with cervical cancer the delivery of chemotherapy with radiotherapy improves survival compared with radiotherapy alone. However, high rates of acute hematologic toxicity occur when combining both therapies due to the damage of the red bone marrow (RBM). This study aimed to reduce the radiation damage to the RBM. A tool has been developed for semi-automatic delineation of the red bone marrow based on MR-only. This delineation can be included into the treatment planning process to reduce the volume of RBM irradiated in patients receiving pelvic radiation therapy...
February 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28236649/spectral-characterization-of-tissues-in-high-spectral-and-spatial-resolution-mr-images-implications-for-a-classification-based-synthetic-ct-algorithm
#13
Abbie M Wood, Steven M Shea, Milica Medved, Gregory S Karczmar, Murat Surucu, Sebastien Gros, William Small, John Roeske
PURPOSE: To characterize spectral parameters of tissues with high spectral and spatial resolution magnetic resonance images to be used as a foundation for a classification-based synthetic CT algorithm. METHODS: A phantom was constructed consisting of a section of fresh beef leg with bone embedded in a 1% agarose gel. The high spectral and spatial (HiSS) resolution MR imaging sequence used had 1.0mm in-plane resolution and 11.1Hz spectral resolution. This sequence was used to image the phantom and one patient...
February 25, 2017: Medical Physics
https://www.readbyqxmd.com/read/28225576/3d-multiecho-dixon-for-the-evaluation-of-hepatic-iron-and-fat-in-a-clinical-setting
#14
Benjamin Henninger, Heinz Zoller, Stephan Kannengiesser, Xiaodong Zhong, Werner Jaschke, Christian Kremser
PURPOSE: To prospectively evaluate a new 3D-multiecho-Dixon (3D-ME-Dixon) sequence for the quantification of hepatic iron and fat in a clinical setting. MATERIALS AND METHODS: In all, 120 patients underwent 1.5T magnetic resonance imaging of the liver between December 2013 and June 2015 including the following three sequences: 3D-ME-Dixon with inline calculation of R2* and proton-density fat-fraction (PDFF) maps, single-voxel-spectroscopy (SVS), 2D multigradient-echo sequence (2D-ME-GRE)...
February 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28216452/water-and-lipid-diffusion-mri-using-chemical-shift-displacement-based-separation-of-lipid-tissue-split
#15
Naoki Ohno, Hirohito Kan, Tosiaki Miyati, Toshitaka Aoki, Shota Ishida, Toshifumi Gabata
PURPOSE: To obtain water and lipid diffusion-weighted images (DWIs) simultaneously, we devised a novel method utilizing chemical shift displacement-based separation of lipid tissue (SPLIT) imaging. MATERIALS AND METHODS: Single-shot diffusion echo-planar imaging without fat suppression was used and the imaging parameters were optimized to separate water and lipid DWIs by chemical shift displacement of the lipid signals along the phase-encoding direction. Using the optimized conditions, transverse DWIs at the maximum diameter of the right calf were scanned with multiple b-values in five healthy subjects...
February 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28190853/high-snr-acquisitions-improve-the-repeatability-of-liver-fat-quantification-using-confounder-corrected-chemical-shift-encoded-mr-imaging
#16
Utaroh Motosugi, Diego Hernando, Curtis Wiens, Peter Bannas, Scott B Reeder
PURPOSE: To determine whether high signal-to-noise ratio (SNR) acquisitions improve the repeatability of liver proton density fat fraction (PDFF) measurements using confounder-corrected chemical shift-encoded magnetic resonance (MR) imaging (CSE-MRI). MATERIALS AND METHODS: Eleven fat-water phantoms were scanned with 8 different protocols with varying SNR. After repositioning the phantoms, the same scans were repeated to evaluate the test-retest repeatability. Next, an in vivo study was performed with 20 volunteers and 28 patients scheduled for liver magnetic resonance imaging (MRI)...
February 13, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28190639/characterizing-white-matter-changes-in-chronic-schizophrenia-a-free-water-imaging-multi-site-study
#17
Lena K L Oestreich, Amanda E Lyall, Ofer Pasternak, Zora Kikinis, Dominick T Newell, Peter Savadjiev, Sylvain Bouix, Martha E Shenton, Marek Kubicki, Thomas J Whitford, Simon McCarthy-Jones
Diffusion tensor imaging (DTI) studies in chronic schizophrenia have found widespread but often inconsistent patterns of white matter abnormalities. These studies have typically used the conventional measure of fractional anisotropy, which can be contaminated by extracellular free-water. A recent free-water imaging study reported reduced free-water corrected fractional anisotropy (FAT) in chronic schizophrenia across several brain regions, but limited changes in the extracellular volume. The present study set out to validate these findings in a substantially larger sample...
February 10, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28168529/imaging-properties-of-3d-printed-materials-multi-energy-ct-of-filament-polymers
#18
James Shin, Ranjit S Sandhu, George Shih
Clinical applications of 3D printing are increasingly commonplace, likewise the frequency of inclusion of 3D printed objects on imaging studies. Although there is a general familiarity with the imaging appearance of traditional materials comprising common surgical hardware and medical devices, comparatively less is known regarding the appearance of available 3D printing materials in the consumer market. This work detailing the CT appearance of a selected number of common filament polymer classes is an initial effort to catalog these data, to provide for accurate interpretation of imaging studies incidentally or intentionally including fabricated objects...
February 6, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28150873/dual-echo-dixon-imaging-with-a-constrained-phase-signal-model-and-graph-cuts-reconstruction
#19
Eric G Stinson, Joshua D Trzasko, Joel G Fletcher, Stephen J Riederer
PURPOSE: The purpose of this work is to derive and demonstrate constrained-phase dual-echo Dixon imaging within a maximum likelihood framework solved with a regularized graph-cuts-guided optimization. THEORY AND METHODS: Dual-echo Dixon reconstruction is fundamentally underdetermined; however, adopting a constrained-phase signal model reduces the number of unknowns and the nonlinear problem can be solved under a maximum likelihood framework. Period shifts in the field map (manifesting as fat/water signal swaps) must also be corrected...
February 2, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28130811/relation-between-brown-adipose-tissue-and-measures-of-obesity-and-metabolic-dysfunction-in-patients-with-cardiovascular-disease
#20
Bas T Franssens, Hans Hoogduin, Tim Leiner, Yolanda van der Graaf, Frank L J Visseren
PURPOSE: To evaluate whether brown adipose tissue (BAT) is present in middle-aged patients with cardiovascular comorbidities and to quantify how BAT presence associates with obesity and metabolic dysfunction. MATERIALS AND METHODS: Supraclavicular and subcutaneous adipose tissue fat-signal-fraction (FF) was determined with 1.5T water-fat magnetic resonance imaging (MRI) in 50 patients with coronary artery disease, cerebrovascular disease, or peripheral artery disease...
January 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
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