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Water fat imaging

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https://www.readbyqxmd.com/read/27898602/novel-high-spatiotemporal-resolution-versus-standard-of-care-dynamic-contrast-enhanced-breast-mri-comparison-of-image-quality
#1
Courtney K Morrison, Leah C Henze Bancroft, Wendy B DeMartini, James H Holmes, Kang Wang, Ryan J Bosca, Frank R Korosec, Roberta M Strigel
OBJECTIVE: Currently, dynamic contrast-enhanced (DCE) breast magnetic resonance imaging (MRI) prioritizes spatial resolution over temporal resolution given the limitations of acquisition techniques. The purpose of our intrapatient study was to assess the ability of a novel high spatial and high temporal resolution DCE breast MRI method to maintain image quality compared with the clinical standard-of-care (SOC) MRI. MATERIALS AND METHODS: Thirty patients, each demonstrating a focal area of enhancement (29 benign, 1 cancer) on their SOC MRI, consented to undergo a research DCE breast MRI on a second date...
November 28, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27890779/fast-triple-spin-echo-dixon-ftsed-sequence-for-water-and-fat-imaging
#2
R Korinek, K Bartusek, Z Starcuk
A number of 'Dixon' techniques based on fast spin echo (FSE) sequence have been proposed and successfully used in many branches of medicine. Some require only one scan, but most of them need multiple scans and long scan times. This article describes a new fast triple-spin-echo Dixon (FTSED) technique suitable for ultra-high field MRI, in which three specific time shifts are introduced in the echo train; thus, three images with defined water-fat phase-differences (0, π, 2π) are encoded in the phase of the acquired images without extreme restrictions upon the echo duration...
November 24, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27861264/use-of-b-mode-ultrasound-as-a-body-fat-estimate-in-collegiate-football-players
#3
Parker N Hyde, Kristina L Kendall, Ciaran M Fairman, Nicholas A Coker, Mary E Yarbrough, Steve J Rossi
Hyde, PN, Kendall, KL, Fairman, CM, Coker, NA, Yarbrough, ME, and Rossi, SJ. Utilization of B-mode ultrasound as a body fat estimate in collegiate football players. J Strength Cond Res 30(12): 3525-3530, 2016-The purpose of the present study was to validate a 7-site ultrasound imaging protocol to predict the percent body fat (%BF) in a division I football team. Body composition was estimated by ultrasound, 7-site skinfolds, and the 3-compartment-water (3C-W) model of Siri, using bioimpedance spectroscopy to estimate the total body water and air displacement plethysmography (using BODPOD) to determine the body density...
December 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27859853/monoexponential-biexponential-and-stretched-exponential-diffusion-weighted-imaging-models-quantitative-biomarkers-for-differentiating-renal-clear-cell-carcinoma-and-minimal-fat-angiomyolipoma
#4
Haojie Li, Lili Liang, Anqin Li, Yao Hu, Daoyu Hu, Zhen Li, Ihab R Kamel
PURPOSE: To determine the utility of various diffusion parameters obtained from monoexponential, biexponential, and stretched exponential diffusion-weighted imaging (DWI) models in differentiating between minimal fat angiomyolipoma (MFAML) and clear cell renal cell carcinoma (ccRCC). MATERIALS AND METHODS: One hundred thirty-one patients with pathologically confirmed MFAML (n = 27) or ccRCC (n = 104) underwent multi-b value DWI (0∼1700 s/mm(2) ) imaging at 3...
November 10, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27854210/skeletal-muscle-quantitative-nuclear-magnetic-resonance-imaging-and-spectroscopy-as-an-outcome-measure-for-clinical-trials
#5
Pierre G Carlier, Benjamin Marty, Olivier Scheidegger, Paulo Loureiro de Sousa, Pierre-Yves Baudin, Eduard Snezhko, Dmitry Vlodavets
Recent years have seen tremendous progress towards therapy of many previously incurable neuromuscular diseases. This new context has acted as a driving force for the development of novel non-invasive outcome measures. These can be organized in three main categories: functional tools, fluid biomarkers and imagery. In the latest category, nuclear magnetic resonance imaging (NMRI) offers a considerable range of possibilities for the characterization of skeletal muscle composition, function and metabolism. Nowadays, three NMR outcome measures are frequently integrated in clinical research protocols...
March 3, 2016: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/27851874/adc-quantification-of-the-vertebral-bone-marrow-water-component-removing-the-confounding-effect-of-residual-fat
#6
Michael Dieckmeyer, Stefan Ruschke, Holger Eggers, Hendrik Kooijman, Ernst J Rummeny, Jan S Kirschke, Thomas Baum, Dimitrios C Karampinos
PURPOSE: To remove the confounding effect of unsuppressed fat on the imaging-based apparent diffusion coefficient (ADC) of the vertebral bone marrow water component when using spectrally selective fat suppression and to compare and validate the proposed quantification strategy against diffusion-weighted magnetic resonance spectroscopy (DW-MRS). METHODS: Twelve subjects underwent diffusion-weighted imaging (DWI) and DW-MRS of the vertebral bone marrow. A theoretical model was developed to take into account and correct the effects of residual fat on ADC, incorporating additional measurements for proton density fat fraction (PDFF) and water T2 (T2w)...
November 8, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27826082/spectrally-presaturated-modulation-spm-an-efficient-fat-suppression-technique-for-steam-based-cardiac-imaging-sequences
#7
Ahmed S Fahmy, El-Sayed H Ibrahim, Nael F Osman
Stimulated-echo acquisition mode (STEAM) is a key pulse sequences in MRI in general, and in cardiac imaging in particular. Fat suppression is an important feature in cardiac imaging to improve visualization and eliminate off-resonance and chemical-shift artifacts. Nevertheless, fat suppression comes at the expense of reduced temporal resolution and signal-to-noise ratio (SNR). The purpose of this study is to develop an efficient fat suppression method (Spectrally-Presaturated Modulation) for STEAM-based sequences to enable imaging with high temporal-resolution, high SNR, and no increase in scan time...
November 4, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27822655/accelerating-multi-echo-water-fat-mri-with-a-joint-locally-low-rank-and-spatial-sparsity-promoting-reconstruction
#8
Felix Lugauer, Dominik Nickel, Jens Wetzl, Berthold Kiefer, Joachim Hornegger, Andreas Maier
OBJECTIVES: Our aim was to demonstrate the benefits of using locally low-rank (LLR) regularization for the compressed sensing reconstruction of highly-accelerated quantitative water-fat MRI, and to validate fat fraction (FF) and [Formula: see text] relaxation against reference parallel imaging in the abdomen. MATERIALS AND METHODS: Reconstructions using spatial sparsity regularization (SSR) were compared to reconstructions with LLR and the combination of both (LLR+SSR) for up to seven fold accelerated 3-D bipolar multi-echo GRE imaging...
November 7, 2016: Magma
https://www.readbyqxmd.com/read/27809381/stability-and-sensitivity-of-water-t2-obtained-with-ideal-cpmg-in-healthy-and-fat-infiltrated-skeletal-muscle
#9
Christopher D J Sinclair, Jasper M Morrow, Robert L Janiczek, Matthew R B Evans, Elham Rawah, Sachit Shah, Michael G Hanna, Mary M Reilly, Tarek A Yousry, John S Thornton
Quantifying muscle water T2 (T2 -water) independently of intramuscular fat content is essential in establishing T2 -water as an outcome measure for imminent new therapy trials in neuromuscular diseases. IDEAL-CPMG combines chemical shift fat-water separation with T2 relaxometry to obtain such a measure. Here we evaluate the reproducibility and B1 sensitivity of IDEAL-CPMG T2 -water and fat fraction (f.f.) values in healthy subjects, and demonstrate the potential of the method to quantify T2 -water variation in diseased muscle displaying varying degrees of fatty infiltration...
December 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27797100/correction-of-phase-errors-in-quantitative-water-fat-imaging-using-a-monopolar-time-interleaved-multi-echo-gradient-echo-sequence
#10
Stefan Ruschke, Holger Eggers, Hendrik Kooijman, Maximilian N Diefenbach, Thomas Baum, Axel Haase, Ernst J Rummeny, Houchun H Hu, Dimitrios C Karampinos
PURPOSE: To propose a phase error correction scheme for monopolar time-interleaved multi-echo gradient echo water-fat imaging that allows accurate and robust complex-based quantification of the proton density fat fraction (PDFF). METHODS: A three-step phase correction scheme is proposed to address a) a phase term induced by echo misalignments that can be measured with a reference scan using reversed readout polarity, b) a phase term induced by the concomitant gradient field that can be predicted from the gradient waveforms, and c) a phase offset between time-interleaved echo trains...
October 31, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27790049/hypermetabolic-conversion-of-plant-oil-into-water-endothermic-biochemical-process-stimulated-by-juvenile-hormone-in-the-european-firebug-pyrrhocoris-apterus-l
#11
Karel Sláma, Jan Lukáš
The physiological and biochemical mechanisms that enable insects to feed on dry food to secure enough water for larval growth were investigated. The study was carried out with a plethora of physiological methods, ranging from the simple volumetric determination of O2 consumption and water intake to more advanced methods such as scanning microrespirography and thermovision imaging of insect's body temperature. The experiments were done on the European firebug, Pyrrhocoris apterus, which feeds exclusively on dry linden seeds...
2016: International Journal of Insect Science
https://www.readbyqxmd.com/read/27789721/sympathetic-innervation-of-cold-activated-brown-and-white-fat-in-lean-young-adults
#12
Otto Muzik, Thomas J Mangner, William R Leonard, Ajay Kumar, James G Granneman
OBJECTIVE: Recent work in rodents has demonstrated that basal activity of local sympathetic nervous system is critical for maintaining brown adipocyte phenotypes in classic brown (BAT) and white adipose tissue (WAT). Accordingly, we sought to assess the relationship between sympathetic innervation and cold-induced activation of BAT and WAT, and its relation to local and whole body daily energy expenditure (DEE, kcal/d) in lean young adults. METHODS: Twenty adult lean normal subjects (10F/10M, 23...
October 27, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27782705/quantification-of-breast-lesion-compositions-using-low-dose-spectral-mammography-a-feasibility-study
#13
Huanjun Ding, David Sennung, Hyo-Min Cho, Sabee Molloi
PURPOSE: The positive predictive power for malignancy can potentially be improved, if the chemical compositions of suspicious breast lesions can be reliably measured in screening mammography. The purpose of this study is to investigate the feasibility of quantifying breast lesion composition, in terms of water and lipid contents, with spectral mammography. METHODS: Phantom and tissue samples were imaged with a spectral mammography system based on silicon-strip photon-counting detectors...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27775180/robust-water-fat-separated-dual-echo-mri-by-phase-sensitive-reconstruction
#14
Thobias Romu, Nils Dahlström, Olof Dahlqvist Leinhard, Magnus Borga
PURPOSE: The purpose of this work was to develop and evaluate a robust water-fat separation method for T1-weighted symmetric two-point Dixon data. THEORY AND METHODS: A method for water-fat separation by phase unwrapping of the opposite-phase images by phase-sensitive reconstruction (PSR) is introduced. PSR consists of three steps; (1), identification of clusters of tissue voxels; (2), unwrapping of the phase in each cluster by solving Poisson's equation; and (3), finding the correct sign of each unwrapped opposite-phase cluster, so that the water-fat images are assigned the correct identities...
October 24, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27773967/ultrasonic-transducer-guided-electrochemical-impedance-spectroscopy-to-assess-lipid-laden-plaques
#15
Jianguo Ma, Yuan Luo, René R Sevag Packard, Teng Ma, Yichen Ding, Parinaz Abiri, Yu-Chong Tai, Qifa Zhou, Kirk K Shung, Rongsong Li, Tzung Hsiai
Plaque rupture causes acute coronary syndromes and stroke. Intraplaque oxidized low density lipoprotein (oxLDL) is metabolically unstable and prone to induce rupture. We designed an intravascular ultrasound (IVUS)-guided electrochemical impedance spectroscopy (EIS) sensor to enhance the detection reproducibility of oxLDL-laden plaques. The flexible 2-point micro-electrode array for EIS was affixed to an inflatable balloon anchored onto a co-axial double layer catheter (outer diameter = 2 mm). The mechanically scanning-driven IVUS transducer (45 MHz) was deployed through the inner catheter (diameter = 1...
November 1, 2016: Sensors and Actuators. B, Chemical
https://www.readbyqxmd.com/read/27738008/4d-mr-and-attenuation-map-generation-in-pet-mr-imaging-using-4d-pet-derived-deformation-matrices-a-feasibility-study-for-lung-cancer-applications
#16
Hadi Fayad, Holger Schmidt, Thomas Kuestner, Dimitris Visvikis
: Respiratory motion may reduce accuracy in fusion of functional and anatomical images using combined Positron emission tomography / Magnetic resonance (PET/MR) systems. Methodologies for the correction of respiratory motion in PET acquisitions using such systems are mostly based on the use of respiratory synchronized MR acquisitions to derive motion fields. Existing approaches based on tagging acquisitions may introduce artifacts in the MR images, while motion model approaches require the acquisition of training datasets...
October 13, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27725802/preclinical-in-vivo-imaging-for-fat-tissue-identification-quantification-and-functional-characterization
#17
Pasquina Marzola, Federico Boschi, Francesco Moneta, Andrea Sbarbati, Carlo Zancanaro
Localization, differentiation, and quantitative assessment of fat tissues have always collected the interest of researchers. Nowadays, these topics are even more relevant as obesity (the excess of fat tissue) is considered a real pathology requiring in some cases pharmacological and surgical approaches. Several weight loss medications, acting either on the metabolism or on the central nervous system, are currently under preclinical or clinical investigation. Animal models of obesity have been developed and are widely used in pharmaceutical research...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27708535/r2-map-by-ideal-iq-for-acute-cerebral-infarction-compared-with-susceptibility-vessel-sign-on-t2-weighted-imaging
#18
Yuki Shinohara, Ayumi Kato, Eijiro Yamashita, Toshihide Ogawa
BACKGROUND: To evaluate the detectability of arterial acute thrombus on R2* map by iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) IQ compared with T2*-weighted imaging (T2*WI). METHODS: Twenty-six patients with acute cerebral infarction who underwent R2* map and T2*WI were reviewed. We performed visual assessment of each sequence regarding the visibility of susceptibility effect reflecting acute thrombus and quantitative evaluation of the thrombus on R2* map...
September 2016: Yonago Acta Medica
https://www.readbyqxmd.com/read/27699867/a-rapid-and-robust-gradient-measurement-technique-using-dynamic-single-point-imaging
#19
Hyungseok Jang, Alan B McMillan
PURPOSE: We propose a new gradient measurement technique based on dynamic single-point imaging (SPI), which allows simple, rapid, and robust measurement of k-space trajectory. METHODS: To enable gradient measurement, we utilize the variable field-of-view (FOV) property of dynamic SPI, which is dependent on gradient shape. First, one-dimensional (1D) dynamic SPI data are acquired from a targeted gradient axis, and then relative FOV scaling factors between 1D images or k-spaces at varying encoding times are found...
October 3, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27649492/upper-limb-evaluation-in-duchenne-muscular-dystrophy-fat-water-quantification-by-mri-muscle-force-and-function-define-endpoints-for-clinical-trials
#20
Valeria Ricotti, Matthew R B Evans, Christopher D J Sinclair, Jordan W Butler, Deborah A Ridout, Jean-Yves Hogrel, Ahmed Emira, Jasper M Morrow, Mary M Reilly, Michael G Hanna, Robert L Janiczek, Paul M Matthews, Tarek A Yousry, Francesco Muntoni, John S Thornton
OBJECTIVE: A number of promising experimental therapies for Duchenne muscular dystrophy (DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation-dependent functional tests to assess outcome. Quantitative muscle magnetic resonance imaging (MRI) could offer a valuable alternative and permit inclusion of non-ambulant DMD subjects. The aims of our study were to explore the responsiveness of upper-limb MRI muscle-fat measurement as a non-invasive objective endpoint for clinical trials in non-ambulant DMD, and to investigate the relationship of these MRI measures to those of muscle force and function...
2016: PloS One
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