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https://www.readbyqxmd.com/read/28807564/reduced-metallic-artefacts-in-3%C3%A2-t-knee-mri-using-fast-spin-echo-multi-point-dixon-compared-to-fast-spin-echo-t2-weighted-sequences
#1
H J Park, S Y Lee, S H Choi, H P Hong, Y J Choi, M S Kim
AIM: To compare multi-point Dixon magnetic resonance imaging (MRI) and fast spin-echo (FSE) T2-weighted imaging (WI) with regard to the size of metallic artefacts when imaging the knee joint. MATERIALS AND METHODS: A total of 42 patients who underwent anterior cruciate ligament (ACL) reconstruction and follow-up imaging with 3 T MRI using the multi-point Dixon technique was included in this retrospective study. The maximal distance of the image distortion area around the metallic artefact was measured (interference screw of femoral tunnel area) on sagittal images of both FSE T2WI (T2WI and fat-suppressed [FS] T2WI) and multi-point Dixon (water only image and in-phase image) sequences...
August 11, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28801960/mri-characterization-of-brown-adipose-tissue-under-thermal-challenges-in-normal-weight-overweight-and-obese-young-men
#2
Jie Deng, Lisa M Neff, Nicholas C Rubert, Bin Zhang, Richard M Shore, Jonathan D Samet, Paige C Nelson, Lewis Landsberg
PURPOSE: To implement quantitative Dixon magnetic resonance imaging (MRI) methods for brown adipose tissue (BAT) characterization at inactive and cold-activated states in normal weight, overweight, and obese subjects. The hypotheses are that MRI characteristics of BAT would differentiate between nonobese and obese subjects, and activation of BAT in response to thermal challenges that are detected by MRI would be correlated with BAT activity measured by positron emission tomography / computed tomography (PET/CT)...
August 11, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28780347/nanoscale-observation-of-the-natural-structure-of-milk-fat-globules-and-casein-micelles-in-the-liquid-condition-using-a-scanning-electron-assisted-dielectric-microscopy
#3
Toshihiko Ogura, Tomoko Okada
Recently, aqueous nanoparticles have been used in drug-delivery systems for new type medicines. In particular, milk-casein micelles have been used as drug nanocarriers for targeting cancer cells. Therefore, nanostructure observation of particles and micelles in their native liquid condition is indispensable for analysing their function and mechanisms. However, traditional optical and scanning electron microscopy have difficulty observing the nanostructures of aqueous micelles. Recently, we developed a novel imaging technique called scanning electron-assisted dielectric microscopy (SE-ADM) that enables observation of various biological specimens in water with very little radiation damage and high-contrast imaging without staining or fixation at an 8-nm spatial resolution...
August 2, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28774580/advancing-imaging-technologies-for-patients-with-spinal-pain-with-a-focus-on-whiplash-injury
#4
James M Elliott, Mark J Hancock, Rebecca J Crawford, Andrew C Smith, David M Walton
BACKGROUND CONTEXT: Radiological observations of soft-tissue changes that may relate to clinical symptoms in patients with traumatic and non-traumatic spinal disorders are highly controversial. Studies are often of poor quality and findings inconsistent. A plethora of evidence suggests some pathoanatomical findings from traditional imaging applications are common in asymptomatic participants across the life span, which further questions the diagnostic, prognostic, and theranostic value of traditional imaging...
July 31, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28745402/fat-based-registration-of-breast-dynamic-contrast-enhanced-water-images
#5
Subashini Srinivasan, Brian A Hargreaves, Bruce L Daniel
PURPOSE: In this study, a 3D fat-based deformable registration algorithm was developed for registering dynamic contrast-enhanced breast images. METHODS: The mutual information similarity measure with free-form deformation motion correction in rapidly enhancing lesions can introduce motion. However, in Dixon-based fat-water separated acquisitions, the nonenhancing fat signal can directly be used to estimate deformable motion, which can be later used to deform the water images...
July 26, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28707256/monitoring-in-vivo-the-mammary-gland-microstructure-during-morphogenesis-from-lactation-to-post-weaning-using-diffusion-tensor-mri
#6
Noam Nissan, Edna Furman-Haran, Myra Shapiro-Feinberg, Dov Grobgeld, Hadassa Degani
Lactation and the return to the pre-conception state during post-weaning are regulated by hormonal induced processes that modify the microstructure of the mammary gland, leading to changes in the features of the ductal / glandular tissue, the stroma and the fat tissue. These changes create a challenge in the radiological workup of breast disorder during lactation and early post-weaning. Here we present non-invasive MRI protocols designed to record in vivo high spatial resolution, T2-weighted images and diffusion tensor images of the entire mammary gland...
July 13, 2017: Journal of Mammary Gland Biology and Neoplasia
https://www.readbyqxmd.com/read/28696961/current-body-composition-measurement-techniques
#7
Thaisa Lemos, Dympna Gallagher
PURPOSE OF REVIEW: The current article reviews the most innovative and precise, available methods for quantification of in-vivo human body composition. RECENT FINDINGS: Body composition measurement methods are continuously being perfected. Ongoing efforts involve multisegmental and multifrequency bioelectrical impedance analysis, quantitative magnetic resonance for total body water, fat, and lean tissue measurements, imaging to further define ectopic fat depots...
July 10, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/28690388/-23-na-mri-and-myometry-to-compare-eplerenone-vs-glucocorticoid-treatment-in-duchenne-dystrophy
#8
Philip A Glemser, Heike Jaeger, Armin M Nagel, Andreas E Ziegler, David Simons, Heinz-Peter Schlemmer, Frank Lehmann-Horn, Karin Jurkat-Rott, Marc-André Weber
In this pilot study we tested whether a low dose application of a mild diuretic substance such as eplerenone is beneficial in early stages of Duchenne muscular dystrophy using (23)Na und (1)H imaging, myometry, and clinical testing versus the glucocorticoid gold standard. Two 7-years old patients with DMD were examined on a 3T MRI system. (1)H MRI and (23)Na density-adapted 3-dimensional radial MRI sequences were performed both before and 1, 3 and 6 months after therapy with eplerenone respectively cortisone...
March 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/28678410/simultaneous-mr-quantification-of-hepatic-fat-content-fatty-acid-composition-transverse-relaxation-time-and-magnetic-susceptibility-for-the-diagnosis-of-non-alcoholic-steatohepatitis
#9
B Leporq, S A Lambert, M Ronot, V Vilgrain, B E Van Beers
Non-alcoholic steatohepatitis (NASH) is characterized at histology by steatosis, hepatocyte ballooning and inflammatory infiltrates, with or without fibrosis. Although diamagnetic material in fibrosis and inflammation can be detected with quantitative susceptibility imaging, fatty acid composition changes in NASH relative to simple steatosis have also been reported. Therefore, our aim was to develop a single magnetic resonance (MR) acquisition and post-processing scheme for the diagnosis of steatohepatitis by the simultaneous quantification of hepatic fat content, fatty acid composition, T2 * transverse relaxation time and magnetic susceptibility in patients with non-alcoholic fatty liver disease...
July 5, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28672007/diagnostic-utility-of-whole-body-dixon-mri-in-multiple-myeloma-a-multi-reader-study
#10
Timothy J P Bray, Saurabh Singh, Arash Latifoltojar, Kannan Rajesparan, Farzana Rahman, Priya Narayanan, Sahar Naaseri, Andre Lopes, Alan Bainbridge, Shonit Punwani, Margaret A Hall-Craggs
OBJECTIVE: To determine which of four Dixon image types [in-phase (IP), out-of-phase (OP), fat only (FO) and water-only (WO)] is most sensitive for detecting multiple myeloma (MM) focal lesions on whole body MRI (WB-MRI) images. METHODS: Thirty patients with clinically-suspected MM underwent WB-MRI at 3 Tesla. Unenhanced IP, OP, FO and WO Dixon images were generated and read by four radiologists. On each image type, each radiologist identified and labelled all visible myeloma lesions in the bony pelvis...
2017: PloS One
https://www.readbyqxmd.com/read/28666972/non-destructive-nir-spectral-imaging-assessment-of-bone-water-comparison-to-mri-measurements
#11
Chamith S Rajapakse, Mugdha V Padalkar, Hee Jin Yang, Mikayel Ispiryan, Nancy Pleshko
Bone fracture risk increases with age, disease states, and with use of certain therapeutics, such as acid-suppressive drugs, steroids and high-dose bisphosphonates. Historically, investigations into factors that underlie bone fracture risk have focused on evaluation of bone mineral density (BMD). However, numerous studies have pointed to factors other than BMD that contribute to fragility, including changes in bone collagen and water. The goal of this study is to investigate the feasibility of using near infrared spectral imaging (NIRSI) to determine the spatial distribution and relative amount of water and organic components in whole cross-sections of bone, and to compare those results to those obtained using magnetic resonance imaging (MRI) methods...
June 28, 2017: Bone
https://www.readbyqxmd.com/read/28643383/multiecho-pseudo-golden-angle-stack-of-stars-thermometry-with-high-spatial-and-temporal-resolution-using-k-space-weighted-image-contrast
#12
Bryant T Svedin, Allison Payne, Bradley D Bolster, Dennis L Parker
PURPOSE: Implement and evaluate a 3D MRI method to measure temperature changes with high spatial and temporal resolution and large field of view. METHODS: A multiecho pseudo-golden angle stack-of-stars (SOS) sequence with k-space weighted image contrast (KWIC) reconstruction was implemented to simultaneously measure multiple quantities, including temperature, initial signal magnitude M(0), transverse relaxation time ( T2*), and water/fat images. Respiration artifacts were corrected using self-navigation...
June 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28620752/fatty-metaplasia-quantification-and-impact-on-regional-myocardial-function-as-assessed-by-advanced-cardiac-mr-imaging
#13
Tomas Lapinskas, Bernhard Schnackenburg, Marc Kouwenhoven, Rolf Gebker, Alexander Berger, Remigijus Zaliunas, Burkert Pieske, Sebastian Kelle
OBJECTIVE: This study aimed to investigate the advantages of recently developed cardiac imaging techniques of fat-water separation and feature tracking to characterize better individuals with chronic myocardial infarction (MI). MATERIALS AND METHODS: Twenty patients who had a previous MI underwent CMR imaging. The study protocol included routine cine and late gadolinium enhancement (LGE) technique. In addition, mDixon LGE imaging was performed in every patient. Left ventricular (LV) circumferential (EccLV) and radial (ErrLV) strain were calculated using dedicated software (CMR(42), Circle, Calgary, Canada)...
June 15, 2017: Magma
https://www.readbyqxmd.com/read/28596576/knee-subchondral-bone-perfusion-and-its-relationship-to-marrow-fat-and-trabeculation-on-multi-parametric-mri-and-micro-ct-in-experimental-ckd
#14
Chao-Ying Wang, Yu-Juei Hsu, Yi-Jen Peng, Herng-Sheng Lee, Yue-Cune Chang, Chih-Shan Chang, Shih-Wei Chiang, Yi-Chih Hsu, Ming-Huang Lin, Guo-Shu Huang
The pathogenesis of chronic kidney disease (CKD) is multifactorial. In the progression of CKD arthropathy, arteriosclerosis may alter the knee subchondral bone marrow by altering blood flow through the bone vasculature. Herein, multi-parametric MRI assessment, including dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), magnetic resonance spectroscopy (MRS), MRI T2*, contrast enhanced MR angiography (CE-MRA), and micro-CT were applied in a rodent nephrectomy model to: 1) investigate the blood perfusion of subchondral bone marrow and its relationship to fat water content and trabeculation pattern in CKD and 2) demonstrate the feasibility of using multi-parametric MRI parameters as imaging biomarkers to evaluate the disease's progression...
June 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28596551/automated-segmentation-of-human-cervical-supraclavicular-adipose-tissue-in-magnetic-resonance-images
#15
Elin Lundström, Robin Strand, Anders Forslund, Peter Bergsten, Daniel Weghuber, Håkan Ahlström, Joel Kullberg
Human brown adipose tissue (BAT), with a major site in the cervical-supraclavicular depot, is a promising anti-obesity target. This work presents an automated method for segmenting cervical-supraclavicular adipose tissue for enabling time-efficient and objective measurements in large cohort research studies of BAT. Fat fraction (FF) and R2(*) maps were reconstructed from water-fat magnetic resonance imaging (MRI) of 25 subjects. A multi-atlas approach, based on atlases from nine subjects, was chosen as automated segmentation strategy...
June 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28572588/hippocampal-atrophy-and-altered-brain-responses-to-pleasant-tastes-among-obese-compared-with-healthy-weight-children
#16
Z L Mestre, A Bischoff-Grethe, D M Eichen, C E Wierenga, D Strong, K N Boutelle
OBJECTIVE: The hippocampus is a key structure implicated in food motivation and intake. Research has shown that the hippocampus is vulnerable to the consumption of a western diet (i.e., high saturated fat and simple carbohydrates). Studies of patients with obesity (OB), compared with healthy weight (HW), show changes in hippocampal volume and response to food cues. Moreover, evidence suggests that OB children, relative to HW, have greater hippocampal response to taste. However, no study has examined the association of hippocampal volume with taste functioning in children...
June 2, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28570033/quantitative-mri-and-spectroscopy-of-bone-marrow
#17
REVIEW
Dimitrios C Karampinos, Stefan Ruschke, Michael Dieckmeyer, Maximilian Diefenbach, Daniela Franz, Alexandra S Gersing, Roland Krug, Thomas Baum
Bone marrow is one of the largest organs in the human body, enclosing adipocytes, hematopoietic stem cells, which are responsible for blood cell production, and mesenchymal stem cells, which are responsible for the production of adipocytes and bone cells. Magnetic resonance imaging (MRI) is the ideal imaging modality to monitor bone marrow changes in healthy and pathological states, thanks to its inherent rich soft-tissue contrast. Quantitative bone marrow MRI and magnetic resonance spectroscopy (MRS) techniques have been also developed in order to quantify changes in bone marrow water-fat composition, cellularity and perfusion in different pathologies, and to assist in understanding the role of bone marrow in the pathophysiology of systemic diseases (e...
June 1, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28540521/comparative-study-of-fat-suppression-techniques-for-hip-arthroplasty-mr-imaging
#18
Sébastien Molière, Jean-Philippe Dillenseger, Matthieu Ehlinger, Stéphane Kremer, Guillaume Bierry
OBJECTIVES: The goal of this study was to evaluate different fat-suppressed fluid-sensitive sequences in association with different metal artifacts reduction techniques (MARS) to determine which combination allows better fat suppression around metallic hip implants. METHODS: An experimental study using an MRI fat-water phantom quantitatively evaluated contrast shift induced by metallic hip implant for different fat-suppression techniques and MARS. Then a clinical study with patients addressed to MRI unit for painful hip prosthesis compared these techniques in terms of fat suppression quality and diagnosis confidence...
September 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28528267/using-mri-to-non-invasively-and-accurately-quantify-preoperative-hepatic-steatosis
#19
Callisia N Clarke, Haesun Choi, Ping Hou, Catherine H Davis, Jingfei Ma, Asif Rashid, Jean-Nicolas Vauthey, Thomas A Aloia
BACKGROUND: The obesity epidemic has significantly increased the incidence and severity of hepatic steatosis in liver surgery patients and liver donors, potentially impacting postoperative liver regeneration and function. Development of a non-invasive means to quantify hepatic steatosis would facilitate selection of candidates for liver resection and transplant donation. METHODS: An IRB-approved protocol prospectively enrolled 28 patients with liver tumors requiring hepatic resection...
May 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28514304/diagnostic-and-clinical-application-value-of-magnetic-resonance-imaging-mri-for-progressive-massive-fibrosis-of-coal-worker-pneumoconiosis-case-reports
#20
Lansheng Zhang, Chun Wang, Qiuyue Yan, Tao Zhang, Zhengxiang Han, Guan Jiang
RATIONALE: Using magnetic resonance imaging (MRI), we diagnosed pneumoconiosis by identifying the content and distribution of hydrogen protons in the water molecules in different tissues and lesions. PATIENT CONCERNS: 25 cases of CWP patients with progressive massive fibrosis (PMF) lesions. DIAGNOSES: Patients were correctly diagnosed, with one case each of Phase I and II pneumoconiosis and 23 cases of Phase III pneumoconiosis. INTERVENTIONS: None...
May 2017: Medicine (Baltimore)
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