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https://www.readbyqxmd.com/read/28530137/intravoxel-incoherent-motion-magnetic-resonance-imaging-of-the-normal-appearing-parotid-glands-in-patients-with-differentiated-thyroid-cancer-after-radioiodine-therapy
#1
Jie Shen, Xiao-Quan Xu, Guo-Yi Su, Hao Hu, Hai-Bin Shi, Wei Liu, Fei-Yun Wu
Background Radiation damage to the salivary gland is a common complication of radioiodine therapy (RIT) in the patients with differentiated thyroid cancer (DTC). Purpose To investigate the feasibility of using intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) to detect radiation-induced changes of normal-appearing parotid glands in the patients after RIT for DTC. Material and Methods We prospectively enrolled 20 patients with RIT-induced sialoadenitis and 20 healthy control (HC) participants...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28523162/a-preliminary-exploration-of-the-intravoxel-incoherent-motion-applied-in-the-preoperative-evaluation-of-mediastinal-lymph-node-metastasis-of-lung-cancer
#2
Xin Ye, Shuo Chen, Yaru Tian, Bin You, Wenqian Zhang, Yan Zhao, Tao Jiang, Bin Hu, Hui Li
BACKGROUND: The aim of this study was to investigate the diagnostic value of the intravoxel incoherent motion (IVIM) for distinguishing non-metastatic from metastatic mediastinal lymph nodes in lung cancer. METHODS: IVIM-diffusion weighted imaging (DWI) exams were performed preoperatively on 66 patients with lung cancer from October 2015 to June 2016 in Beijing Chao-Yang Hospital, Capital Medical University. Fifty patients underwent enhanced chest computed tomography (CT) in our hospital, while the other 16 patients already had enhanced chest CT images when they were admitted...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28515412/utility-of-a-hybrid-ivim-dki-model-to-predict-the-development-of-distant-metastasis-in-head-and-neck-squamous-cell-carcinoma-patients
#3
Noriyuki Fujima, Tomohiro Sakashita, Akihiro Homma, Daisuke Yoshida, Kohsuke Kudo, Hiroki Shirato
PURPOSE: To evaluate the diagnostic power of hybrid intravoxel incoherent motion (IVIM)-diffusion kurtosis imaging (DKI) model parameters in pretreatment for the prediction of future distant metastasis in head and neck squamous cell carcinoma (HNSCC) patients. MATERIALS AND METHODS: We retrospectively evaluated 49 HNSCC patients who underwent curative chemoradiation therapy. Diffusion-weighted image (DWI) acquired by single-shot spin-echo echo-planar imaging with 12 b-values (0-2000) was performed in all patients before any treatment...
May 18, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28514733/role-of-intravoxel-incoherent-motion-mr-imaging-in-preoperative-assessing-her2-status-of-gastric-cancers
#4
Changfeng Ji, Qinglei Zhang, Wenxian Guan, Tingting Guo, Ling Chen, Song Liu, Jian He, Zhengyang Zhou
PURPOSE: To explore the role of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging in evaluating human epidermal growth factor receptor 2 (HER2) status of gastric cancers preoperatively. RESULTS: The apparent diffusion coefficient (ADC) and pure diffusion coefficient (D) values correlated positively with HER2 scores of gastric cancers significantly (r = 0.276, P = 0.048; r = 0.481, P < 0.001, respectively). The ADC and D values of HER2 positive gastric cancers were significantly higher than those of HER2 negative tumors (P = 0...
May 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28513892/assessment-of-nonarteritic-anterior-ischemic-optic-neuropathy-with-intravoxel-incoherent-motion-diffusion-weighted-imaging-using-readout-segmented-echo-planar-imaging-parallel-imaging-and-2d-navigator-based-reacquisition
#5
Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tan, Wenlin Tang
PURPOSE: To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS: Orbital IVIM in a 3.0T scanner was performed on 33 patients with NAION and 15 controls using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-IVIM)...
May 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28489784/rectal-cancer-short-term-reproducibility-of-intravoxel-incoherent-motion-parameters-in-3-0t-magnetic-resonance-imaging
#6
Hongliang Sun, Yanyan Xu, Qiaoyu Xu, Kaining Shi, Wu Wang
The aim of this study was to evaluate the short-term test-retest reproducibility of diffusion-weighted magnetic resonance imaging (DW-MRI) parameters of rectal cancer with 3.0T MRI.Twenty-six patients with rectal cancer underwent MRI, including diffusion-weighted imaging with 8 b values. Apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) parameters (D, pure diffusion; f, perfusion fraction; D*, pseudodiffusion coefficient) were, respectively, calculated. The short-term test-retest reproducibility, the intra and interobserver variation of the IVIM parameters were assessed based on the repeatability coefficient and Bland-Altman limits of agreement...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28487658/early-changes-in-glutamate-metabolism-and-perfusion-in-basal-ganglia-following-hypoxia-ischemia-in-neonatal-piglets-a-multi-sequence-3-0t-mr-study
#7
Yu-Xue Dang, Kai-Ning Shi, Xiao-Ming Wang
The excitotoxicity of glutamate metabolism as well as hemodynamic disorders of the brain are both risk factors for neonatal hypoxic-ischemic brain damage (HIBD). In the present study, changes in glutamate metabolism in the basal ganglia were detected by proton magnetic resonance spectroscopy ((1)H-MRS) at 0-6, 8-12, 24-30, and 48-60 h after the induction of hypoxia-ischemia (HI) in newborn piglets. Meanwhile, correlation analysis was performed by combining the microcirculatory perfusion informations acquired by intravoxel incoherent motion (IVIM) scan to explore their possible interaction mechanism...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28487383/monitoring-tumor-response-to-anti-vascular-therapy-using-non-contrast-intravoxel-incoherent-motion-diffusion-weighted-mri
#8
Changzheng Shi, Dexiang Liu, Zeyu Xiao, Dong Zhang, Guanfu Liu, Guanshu Liu, Hanwei Chen, Liangping Luo
Anti-vascular therapy is a promising approach to the treatment of non-small-cell lung cancer (NSCLC), where an imaging modality capable of longitudinally monitoring treatment response could provide early prediction of the outcome. In this study, we sought to investigate the feasibility of using intravoxel incoherent motion (IVIM) diffusion MRI to quantitatively assess the efficacy of the treatments of a vascular disrupting agent CA4P or its combination with bevacizumab (BV) on experimental NSCLC tumors. CA4P caused a strong but reversible effect on tumor vasculature: all perfusion-related parameters-D*, f, fD*, and K(trans)-initially showed a decrease of 30%-60% at two hours and then fully recovered to baseline on day 2 for CA4P treatment or on days 4-8 for CA4P + BV treatment; the diffusion coefficient in tumors decreased initially at two hours and then increased from day 2 to day 8...
May 9, 2017: Cancer Research
https://www.readbyqxmd.com/read/28480534/comparison-of-perfusion-signal-acquired-by-arterial-spin-labeling-prepared-intravoxel-incoherent-motion-ivim-mri-and-conventional-ivim-mri-to-unravel-the-origin-of-the-ivim-signal
#9
Xingxing Zhang, Carson Ingo, Wouter M Teeuwisse, Zhensen Chen, Matthias J P van Osch
PURPOSE: Applications of intravoxel incoherent motion (IVIM) imaging in the brain are scarce, whereas it has been successfully applied in other organs with promising results. To better understand the cerebral IVIM signal, the diffusion properties of the arterial blood flow within different parts of the cerebral vascular tree (i.e., different generations of the branching pattern) were isolated and measured by employing an arterial spin labeling (ASL) preparation module before an IVIM readout...
May 7, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28464745/diffusion-weighted-magnetic-resonance-imaging-of-rectal-cancer-tumour-volume-and-perfusion-fraction-predict-chemoradiotherapy-response-and-survival
#10
Kine Mari Bakke, Knut Håkon Hole, Svein Dueland, Krystyna Kotanska Grøholt, Kjersti Flatmark, Anne Hansen Ree, Therese Seierstad, Kathrine Røe Redalen
BACKGROUND: In locally advanced rectal cancer (LARC), responses to preoperative treatment are highly heterogeneous and more accurate diagnostics are likely to enable more individualised treatment approaches with improved responses. We investigated the potential of diffusion-weighted magnetic resonance imaging (DW MRI), with quantification of the apparent diffusion coefficient (ADC) and perfusion fraction (F), as well as volumetry from T2-weighted (T2W) MRI, for prediction of therapeutic outcome...
June 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28458603/assessment-of-cervical-cancer-with-a-parameter-free-intravoxel-incoherent-motion-imaging-algorithm
#11
Anton S Becker, Jose A Perucho, Moritz C Wurnig, Andreas Boss, Soleen Ghafoor, Pek-Lan Khong, Elaine Y P Lee
OBJECTIVE: To evaluate the feasibility of a parameter-free intravoxel incoherent motion (IVIM) approach in cervical cancer, to assess the optimal b-value threshold, and to preliminarily examine differences in the derived perfusion and diffusion parameters for different histological cancer types. MATERIALS AND METHODS: After Institutional Review Board approval, 19 female patients (mean age, 54 years; age range, 37-78 years) gave consent and were enrolled in this prospective magnetic resonance imaging study...
May 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28454564/intravoxel-incoherent-motion-dwi-of-the-pancreatic-adenocarcinomas-monoexponential-and-biexponential-apparent-diffusion-parameters-and-histopathological-correlations
#12
Chao Ma, Yanjun Li, Li Wang, Yang Wang, Yong Zhang, He Wang, Shiyue Chen, Jianping Lu
BACKGROUND: To investigate the associations between the diffusion parameters obtained from multiple-b-values diffusion weighted imaging (DWI) of pancreatic ductal adenocarcinoma (PDAC) and the aggressiveness and local stage prediction, and assess the values of the quantitative parameters for the discrimination of tumors from healthy pancreas. METHODS: Fifty-one patients with surgical pathology-proven PDAC (size, 35 ± 12 mm) and fifty-seven healthy volunteers were enrolled...
April 28, 2017: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/28438298/intravoxel-incoherent-motion-magnetic-resonance-imaging-in-head-and-neck-cancer-a-systematic-review-of-the-diagnostic-and-prognostic-value
#13
REVIEW
Daniel P Noij, Roland M Martens, J Tim Marcus, Remco de Bree, C René Leemans, Jonas A Castelijns, Marcus C de Jong, Pim de Graaf
Intravoxel incoherent motion (IVIM) imaging is increasingly applied in the assessment of head and neck cancer (HNC). Our purpose was to determine the diagnostic and prognostic performance of IVIM in HNC by performing a critical review of the literature. Pubmed and EMBASE were searched until May 2016. Study and patients characteristics, imaging protocol and diagnostic or prognostic outcomes were extracted by 2 independent reviewers. The studied IVIM parameters were diffusion coefficient (D), pseudodiffusion coefficient (D∗), and perfusion fraction (f)...
May 2017: Oral Oncology
https://www.readbyqxmd.com/read/28423540/correlations-between-intravoxel-incoherent-motion-ivim-parameters-and-histological-findings-in-rectal-cancer-preliminary-results
#14
Alexey Surov, Hans Jonas Meyer, Anne-Kathrin Höhn, Curd Behrmann, Andreas Wienke, Rolf Peter Spielmann, Nikita Garnov
Our purpose was to correlate different intravoxel incoherent motion (IVIM), histopathological and clinical parameters in rectal cancer. 17 patients with histologically proven rectal cancer investigated on a 3.T device were included into the study. DWI was performed using a multi-slice single-shot echo-planar imaging sequence with b values of 0, 50, 200, 500 and 1000 s/mm.2 A polygonal region of interest was drawn within the tumors on every b image. The following parameters were retrieved from IVIM: apparent diffusion coefficient (ADC), true diffusion (D), pseudo diffusion coefficient (D*), perfusion factor (f), and relative perfusion f·D*...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28419705/intravoxel-incoherent-motion-mri-for-the-differentiation-of-benign-intermediate-and-malignant-solid-soft-tissue-tumors
#15
Haijun Wu, Shuixing Zhang, Changhong Liang, Hui Liu, Yanhui Liu, Yingjie Mei, Hongjun Liu, Zaiyi Liu, Fangping Xu
PURPOSE: To determine the diagnostic potential of apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM)-derived parameters for the differentiation of benign, intermediate, and malignant solid soft-tissue tumors. MATERIALS AND METHODS: The Institutional Review Board approved this prospective study, and informed consent was obtained. IVIM imaging was performed in 64 patients including 44 benign, 6 intermediate, and 14 malignant solid soft-tissue tumors at 1...
April 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28412443/separating-blood-and-water-perfusion-and-free-water-elimination-from-diffusion-mri-in-the-human-brain
#16
Anna S Rydhög, Filip Szczepankiewicz, Ronnie Wirestam, André Ahlgren, Carl-Fredrik Westin, Linda Knutsson, Ofer Pasternak
The assessment of the free water fraction in the brain provides important information about extracellular processes such as atrophy and neuroinflammation in various clinical conditions as well as in normal development and aging. Free water estimates from diffusion MRI are assumed to account for freely diffusing water molecules in the extracellular space, but may be biased by other pools of molecules in rapid random motion, such as the intravoxel incoherent motion (IVIM) of blood, where water molecules perfuse in the randomly oriented capillary network...
April 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28410964/comparison-of-turbo-spin-echo-and-echo-planar-imaging-for-intravoxel-incoherent-motion-and-diffusion-tensor-imaging-of-the-kidney-at-3tesla
#17
Fabian Hilbert, Tobias Wech, Henning Neubauer, Simon Veldhoen, Thorsten Alexander Bley, Herbert Köstler
Echo Planar Imaging (EPI) is most commonly applied to acquire diffusion-weighted MR-images. EPI is able to capture an entire image in very short time, but is prone to distortions and artifacts. In diffusion-weighted EPI of the kidney severe distortions may occur due to intestinal gas. Turbo Spin Echo (TSE) is robust against distortions and artifacts, but needs more time to acquire an entire image compared to EPI. Therefore, TSE is more sensitive to motion during the readout. In this study we compare diffusion-weighted TSE and EPI of the human kidney with regard to intravoxel incoherent motion (IVIM) and diffusion tensor imaging (DTI)...
April 12, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28383778/the-effect-of-noise-and-lipid-signals-on-determination-of-gaussian-and-non-gaussian-diffusion-parameters-in-skeletal-muscle
#18
Donnie Cameron, Mustapha Bouhrara, David A Reiter, Kenneth W Fishbein, Seongjin Choi, Christopher M Bergeron, Luigi Ferrucci, Richard G Spencer
This work characterizes the effect of lipid and noise signals on muscle diffusion parameter estimation in several conventional and non-Gaussian models, the ultimate objectives being to characterize popular fat suppression approaches for human muscle diffusion studies, to provide simulations to inform experimental work and to report normative non-Gaussian parameter values. The models investigated in this work were the Gaussian monoexponential and intravoxel incoherent motion (IVIM) models, and the non-Gaussian kurtosis and stretched exponential models...
April 6, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28380018/image-denoising-substantially-improves-accuracy-and-precision-of-intravoxel-incoherent-motion-parameter-estimates
#19
Carolin Reischauer, Andreas Gutzeit
Applicability of intravoxel incoherent motion (IVIM) imaging in the clinical setting is hampered by the limited reliability in particular of the perfusion-related parameter estimates. To alleviate this problem, various advanced postprocessing methods have been introduced. However, the underlying algorithms are not readily available and generally suffer from an increased computational burden. Contrary, several computationally fast image denoising methods have recently been proposed which are accessible online and may improve reliability of IVIM parameter estimates...
2017: PloS One
https://www.readbyqxmd.com/read/28374076/selection-for-biopsy-of-kidney-transplant-patients-by-diffusion-weighted-mri
#20
Philipp Steiger, Sebastiano Barbieri, Anja Kruse, Michael Ith, Harriet C Thoeny
OBJECTIVES: To assess retrospectively whether diffusion-weighted magnetic resonance imaging (DW-MRI) allows physicians to determine the severity of histopathologic findings in biopsies of renal allograft patients with deteriorating renal function. METHODS: Forty consecutive kidney transplant patients underwent DW-MRI and biopsy. Patients were assigned to one group with severe and to another group with normal or mild histopathologic findings. These two groups were compared based on a qualitative DW-MRI assessment (homo-/heterogeneity) and the combination of qualitative and quantitative DW-MRI parameters (ADC, and intravoxel incoherent motion, IVIM, parameters: D, f, D*)...
April 3, 2017: European Radiology
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