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https://www.readbyqxmd.com/read/28830134/split-dose-bowel-preparation-for-colonoscopy-2-liters-polyethylene-glycol-with-ascorbic-acid-versus-sodium-picosulfate-versus-oral-sodium-phosphate-tablets
#1
Seok Won Lee, Chang Seok Bang, Tae Young Park, Ki Tae Suk, Gwang Ho Baik, Dong Joon Kim
Background/Aims: Adequate bowel preparation is an essential factor affecting the visibility of colonic mucosa and safety of related therapeutic interventions. The aim of this study was to assess the efficacy, tolerability, and safety of three bowel preparation agents -2 L polyethylene glycol with ascorbic acid (PEGA), sodium picosulfate magnesium citrate (SPMC), and oral sodium phosphate tablet (NaP)- for morning colonoscopy. Methods: Here, we analyzed the medical records of patients who had taken bowel preparation agents using the split-dose method and undergone colonoscopy in a single hospital...
August 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28830098/enhancing-genetic-gain-in-the-era-of-molecular-breeding
#2
Yunbi Xu, Ping Li, Cheng Zou, Yanli Lu, Chuanxiao Xie, Xuecai Zhang, Boddupalli M Prasanna, Michael S Olsen
As one of the important concepts in conventional quantitative genetics and breeding, genetic gain can be defined as the amount of increase in performance that is achieved annually through artificial selection. To develop pro ducts that meet the increasing demand of mankind, especially for food and feed, in addition to various industrial uses, breeders are challenged to enhance the potential of genetic gain continuously, at ever higher rates, while they close the gaps that remain between the yield potential in breeders' demonstration trials and the actual yield in farmers' fields...
May 17, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28830078/reproducing-epidemiologic-research-and-ensuring-transparency
#3
Steven S Coughlin
Measures for ensuring that epidemiologic studies are reproducible include making data sets and software available to other researchers so they can verify published findings, conduct alternative analyses of the data, and check for statistical errors or programming errors. Recent developments related to the reproducibility and transparency of epidemiologic studies include the creation of a global platform for sharing data from clinical trials and the anticipated future extension of the global platform to non-clinical trial data...
August 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28830058/contrast-enhanced-ultrasonography-of-the-liver-using-sonovue
#4
Giovanna Ferraioli, Maria Franca Meloni
This review focuses on the use of contrast-enhanced ultrasonography (CEUS) with SonoVue Epub ahead of print (Bracco Imaging) for the diagnosis of focal liver lesions (FLLs), guidance during ablative treatment, and follow-up of liver tumors. Multicenter trials have shown that the performance of CEUS for the characterization of FLLs is similar to that of contrast-enhanced computed tomography or contrast-enhanced magnetic resonance imaging. CEUS with SonoVue has been effectively used for guiding the percutaneous treatment of malignant liver tumors that are invisible or poorly visualized in traditional gray-scale ultrasonography...
July 12, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28830055/biochar-induced-negative-carbon-mineralization-priming-effects-in-a-coastal-wetland-soil-roles-of-soil-aggregation-and-microbial-modulation
#5
Hao Zheng, Xiao Wang, Xianxiang Luo, Zhenyu Wang, Baoshan Xing
Biochar can sequestrate carbon (C) in soils and affect native soil organic carbon (SOC) mineralization via priming effects. However, the roles of soil aggregation and microbial regulation in priming effects of biochars on SOC in coastal wetland soils are poorly understood. Thus, a coastal wetland soil (δ(13)C -22‰) was separated into macro-micro aggregates (53-2000μm, MA) and silt-clay fractions (<53μm, SF) to investigate the priming effect using two (13)C enriched biochars produced from corn straw (δ(13)C -11...
August 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28830045/climate-warming-causes-declines-in-crop-yields-and-lowers-school-attendance-rates-in-central-africa
#6
Trevon L Fuller, Paul R Sesink Clee, Kevin Y Njabo, Anthony Tróchez, Katy Morgan, Demetrio Bocuma Meñe, Nicola M Anthony, Mary Katherine Gonder, Walter R Allen, Rachid Hanna, Thomas B Smith
Although a number of recent studies suggest that climate associated shifts in agriculture are affecting social and economic systems, there have been relatively few studies of these effects in Africa. Such studies would be particularly useful in Central Africa, where the impacts of climate warming are predicted to be high but coincide with an area with low adaptive capacity. Focusing on plantain (Musa paradisiaca), we assess whether recent climate change has led to reduced yields. Analysis of annual temperature between 1950 and 2013 indicated a 0...
August 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28830000/fate-and-abundance-of-classical-and-heteroatomic-naphthenic-acid-species-after-advanced-oxidation-processes-insights-and-indicators-of-transformation-and-degradation
#7
Mohamed N A Meshref, Pamela Chelme-Ayala, Mohamed Gamal El-Din
The toxicological effects from all components in oil sands process-affected water (OSPW) are not known. Alternatively, monitoring the variations and abundance of different classes and compounds after treatments might be a useful approach in OSPW remediation. In this study, the variations in the compositions of classical and heteroatomic naphthenic acids (NAs) after treatment using advanced oxidation processes (AOPs), mainly ozone and peroxone, and two different mass spectrometry methods; ultra-performance liquid chromatography time-of-flight (UPLC-TOFMS) and Fourier transform ion cyclotron resonance (FTICR-MS), were examined...
August 4, 2017: Water Research
https://www.readbyqxmd.com/read/28829996/the-role-of-inattention-and-hyperactivity-impulsivity-in-the-fine-motor-coordination-in-children-with-adhd
#8
Javier Fenollar-Cortés, Ana Gallego-Martínez, Luis J Fuentes
OBJECTIVE: Deficits in fine motor coordination have been suggested to be associated with Attention-Deficit/Hyperactivity Disorder (ADHD). However, despite the negative impact of poor fine motor skills on academic achievement, researchers have paid little attention to this problem. The aim of this study was to explore the relationship between ADHD dimensions and fine motor performance. METHOD: Participants were 43 children with a diagnosis of ADHD aged between 7 and 14 years (M=9...
August 19, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28829956/adsorption-of-5f-electron-atoms-thcm-on-graphene-surface-an-all-electron-zora-dft-study
#9
Jiguang Du, Gang Jiang
All-electron calculations were performed to investigate the adsorption of 5f-electron atoms (An=ThCm) on graphene surface. The hollow site is energetically preferred for the An-graphene complexes studied. The interaction strengths between An and C decrease in the order of Th>Pa>U>Np>Pu>Cm>Am. The AnC interactions show predominately closed-shell characteristics, meanwhile ThC chemical bond formed through orbital overlaps of Th (6d) and C (2p) possesses partial covalent nature. The participation of 6d(5f)-electron into bonding orbitals are gradually weakened (enhanced) from Th to Pu because the 5f electrons are more and more diffuse...
August 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28829951/collagenase-treatment-enhances-proteomic-coverage-of-low-abundance-proteins-in-decellularized-matrix-bioscaffolds
#10
Miljan Kuljanin, Cody F C Brown, Matthew J Raleigh, Gilles A Lajoie, Lauren E Flynn
There is great interest in the application of advanced proteomic techniques to characterize decellularized tissues in order to develop a deeper understanding of the effects of the complex extracellular matrix (ECM) composition on the cellular response to these pro-regenerative bioscaffolds. However, the identification of proteins in ECM-derived bioscaffolds is hindered by the high abundance of collagen in the samples, which can interfere with the detection of lower-abundance constituents that may be important regulators of cell function...
August 13, 2017: Biomaterials
https://www.readbyqxmd.com/read/28829946/the-proprioceptive-system-masterminds-spinal-alignment-insight-into-the-mechanism-of-scoliosis
#11
Ronen Blecher, Sharon Krief, Tal Galili, Inbal E Biton, Tomer Stern, Eran Assaraf, Ditsa Levanon, Elena Appel, Yoram Anekstein, Gabriel Agar, Yoram Groner, Elazar Zelzer
Maintaining posture requires tight regulation of the position and orientation of numerous spinal components. Yet, surprisingly little is known about this regulatory mechanism, whose failure may result in spinal deformity as in adolescent idiopathic scoliosis. Here, we use genetic mouse models to demonstrate the involvement of proprioception in regulating spine alignment. Null mutants for Runx3 transcription factor, which lack TrkC neurons connecting between proprioceptive mechanoreceptors and spinal cord, developed peripubertal scoliosis not preceded by vertebral dysplasia or muscle asymmetry...
August 21, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28829926/enhanced-recovery-after-surgery-a-new-standard-for-perioperative-care
#12
Edward E Whang, Matthias F Stopfkuchen-Evans
No abstract text is available yet for this article.
August 22, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28829912/biomolecular-steric-hindrance-effects-are-enhanced-on-nanostructured-microelectrodes
#13
Sahar Sadat Mahshid, Alexis Vallée-Bélisle, Shana O Kelley
The availability of rapid approaches for quantitative detection of biomarkers would drastically impact global health by enabling decentralized disease diagnosis anywhere that patient care is administered. A promising new approach, the electrochemical steric hindrance hybridization assay (eSHHA) has been introduced for quantitative detection of large proteins (e.g. antibodies) with a low nano-molar detection limit within 10 minutes. Here, we report the use of a nanostructured microelectrode (NME) platform for eSHHA that improves the performance of this approach by increasing the efficiency and kinetics of DNA hybridization...
August 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28829821/a-meta-analysis-is-there-any-association-between-mir-608-rs4919510-polymorphism-and-breast-cancer-risks
#14
Jing Wang, Xiangyi Kong, Zeyu Xing, Xiangyu Wang, Jie Zhai, Yi Fang, Jidong Gao
OBJECT: To combine the data from previously conducted studies about the associations between miR-608 rs4919510 polymorphism (C>G) and breast cancer risks. METHODS: According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a systematic review of the related literatures searched from PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Internet (CNKI) (time: ~ December 2016). Using DerSimonian-Laird random-effects models [Pooling Model: Mantel Haenszel (MH)], odd ratios (ORs) with 95% confidence intervals (95% CIs) were estimated in the allele model, homozygote model, heterozygote model, dominant model and recessive model...
2017: PloS One
https://www.readbyqxmd.com/read/28829820/residency-and-movement-patterns-of-an-apex-predatory-shark-galeocerdo-cuvier-at-the-galapagos-marine-reserve
#15
David Acuña-Marrero, Adam N H Smith, Neil Hammerschlag, Alex Hearn, Marti J Anderson, Hannah Calich, Matthew D M Pawley, Chris Fischer, Pelayo Salinas-de-León
The potential effectiveness of marine protected areas (MPAs) as a conservation tool for large sharks has been questioned due to the limited spatial extent of most MPAs in contrast to the complex life history and high mobility of many sharks. Here we evaluated the movement dynamics of a highly migratory apex predatory shark (tiger shark Galeocerdo cuvier) at the Galapagos Marine Reserve (GMR). Using data from satellite tracking passive acoustic telemetry, and stereo baited remote underwater video, we estimated residency, activity spaces, site fidelity, distributional abundances and migration patterns from the GMR and in relation to nesting beaches of green sea turtles (Chelonia mydas), a seasonally abundant and predictable prey source for large tiger sharks...
2017: PloS One
https://www.readbyqxmd.com/read/28829807/meld-mixed-effects-for-large-datasets
#16
Dylan M Nielson, Per B Sederberg
Mixed effects models provide significant advantages in sensitivity and flexibility over typical statistical approaches to neural data analysis, but mass univariate application of mixed effects models to large neural datasets is computationally intensive. Threshold free cluster enhancement also provides a significant increase in sensitivity, but requires computationally-intensive permutation-based significance testing. Not surprisingly, the combination of mixed effects models with threshold free cluster enhancement and nonparametric permutation-based significance testing is currently completely impractical...
2017: PloS One
https://www.readbyqxmd.com/read/28829783/usa-national-phenology-network-s-volunteer-contributed-observations-yield-predictive-models-of-phenological-transitions
#17
Theresa M Crimmins, Michael A Crimmins, Katharine L Gerst, Alyssa H Rosemartin, Jake F Weltzin
PURPOSE: In support of science and society, the USA National Phenology Network (USA-NPN) maintains a rapidly growing, continental-scale, species-rich dataset of plant and animal phenology observations that with over 10 million records is the largest such database in the United States. The aim of this study was to explore the potential that exists in the broad and rich volunteer-collected dataset maintained by the USA-NPN for constructing models predicting the timing of phenological transition across species' ranges within the continental United States...
2017: PloS One
https://www.readbyqxmd.com/read/28829777/the-activation-of-oseil1-on-yuc8m-transcription-and-auxin-biosynthesis-is-required-for-ethylene-inhibited-root-elongation-in-rice-early-seedling-development
#18
Hua Qin, Zhijin Zhang, Juan Wang, Xinbing Chen, Pengcheng Wei, Rongfeng Huang
Rice is an important monocotyledonous crop worldwide; it differs from the dicotyledonous plant Arabidopsis in many aspects. In Arabidopsis, ethylene and auxin act synergistically to regulate root growth and development. However, their interaction in rice is still unclear. Here, we report that the transcriptional activation of OsEIL1 on the expression of YUC8/REIN7 and indole-3-pyruvic acid (IPA)-dependent auxin biosynthesis is required for ethylene-inhibited root elongation. Using an inhibitor of YUC activity, which regulates auxin biosynthesis via the conversion of IPA to indole-3-acetic acid (IAA), we showed that ethylene-inhibited primary root elongation is dependent on YUC-based auxin biosynthesis...
August 22, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28829773/caenorhabditis-elegans-atpase-inhibitor-factor-1-if1-mai-2-preserves-the-mitochondrial-membrane-potential-%C3%AE-%C3%AF-m-and-is-important-to-induce-germ-cell-apoptosis
#19
L P Fernández-Cárdenas, E Villanueva-Chimal, L S Salinas, C José-Nuñez, M Tuena de Gómez Puyou, R E Navarro
When the electrochemical proton gradient is disrupted in the mitochondria, IF1 (Inhibitor Factor-1) inhibits the reverse hydrolytic activity of the F1Fo-ATP synthase, thereby allowing cells to conserve ATP at the expense of losing the mitochondrial membrane potential (Δψm). The function of IF1 has been studied mainly in different cell lines, but these studies have generated contrasting results, which have not been helpful to understand the real role of this protein in a whole organism. In this work, we studied IF1 function in Caenorhabditis elegans to understand IF1´s role in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28829770/combinatorial-regulation-of-a-blimp1-prdm1-enhancer-in-the-mouse-retina
#20
Taylor S Mills, Tatiana Eliseeva, Stephanie M Bersie, Grace Randazzo, Jhenya Nahreini, Ko Uoon Park, Joseph A Brzezinski
The mouse retina comprises seven major cell types that exist in differing proportions. They are generated from multipotent progenitors in a stochastic manner, such that the relative frequency of any given type generated changes over time. The mechanisms determining the proportions of each cell type are only partially understood. Photoreceptors and bipolar interneurons are derived from cells that express Otx2. Within this population, Blimp1 (Prdm1) helps set the balance between photoreceptors and bipolar cells by suppressing bipolar identity in most of the cells...
2017: PloS One
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