keyword
https://read.qxmd.com/read/38481293/efficacy-of-a-virtual-reality-based-cognitive-interactive-training-program-for-children-with-traumatic-brain-injuries-study-protocol-for-a-parallel-group-randomized-controlled-trial
#21
JOURNAL ARTICLE
Jiabin Shen, Yan Wang, Susan Quinn, Stacy J Suskauer, Julia Birch, Tyler Busch, Adrian Svingos, Roger Crawfis, Keith Owen Yeates, H Gerry Taylor
BACKGROUND: Traumatic brain injury (TBI) is a leading cause of disability in children. Cognitive rehabilitation for this population is critical for their long-term health outcomes. This trial aims to evaluate the efficacy of a virtual reality-based program (VICT) for training executive functions in children with TBI. METHODS: A parallel group randomized controlled trial will be conducted among up to 32 children with TBI. Children in the intervention group will receive the VICT training while children in the control group will play a comparable VR game without executive function training...
March 13, 2024: Trials
https://read.qxmd.com/read/38472985/instrumented-balance-error-scoring-system-in-children-and-adolescents-a-cross-sectional-study
#22
JOURNAL ARTICLE
Nils K T Schönberg, Julius Poppel, David Howell, Johanna Wagner, Michael Höfinger, Nicole Fabri, Elena M Bonke, Philine Rojczyk, Matthias Hösl, Lorenz Kiwull, Sebastian A Schröder, Astrid Blaschek, Katharina Vill, Inga K Koerte, Doreen Huppert, Florian Heinen, Michaela V Bonfert
Background: The Balance Error Scoring System (BESS) is a commonly used method for clinically evaluating balance after traumatic brain injury. The utilization of force plates, characterized by their cost-effectiveness and portability, facilitates the integration of instrumentation into the BESS protocol. Despite the enhanced precision associated with instrumented measures, there remains a need to determine the clinical significance and feasibility of such measures within pediatric cohorts. Objective: To report a comprehensive set of posturographic measures obtained during instrumented BESS and to examine the concurrent validity, reliability, and feasibility of instrumented BESS in the pediatric point of care setting...
February 28, 2024: Diagnostics
https://read.qxmd.com/read/38471125/polytrauma-in-children%C3%A2-epidemiology-acute-diagnostic-evaluation-and-treatment
#23
REVIEW
Monica Christine Ciorba, Marc Maegele
BACKGROUND: Inadequate clinical experience still causes uncertainty in the acute diagnostic evaluation and treatment of polytrauma in children (with or without coagulopathy). This review deals with the main aspects of the acute care of severely injured children in the light of current guidelines and other relevant literature, in particular airway control, volume and coagulation management, acute diagnostic imaging, and blood coagulation studies in the shock room. METHODS: This review is based on literature retrieved by a selective search in PubMed, Medline (OVIDSP), the Cochrane Central Register of Controlled Trials, and Epistemonikos covering the period January 2001 to August 2023...
May 17, 2024: Deutsches Ärzteblatt International
https://read.qxmd.com/read/38470144/in-reply-development-of-a-randomized-trial-comparing-icp-monitor-based-management-of-severe-pediatric-traumatic-brain-injury-to-management-based-on-imaging-and-clinical-examination-without-icp-monitoring-study-protocol
#24
JOURNAL ARTICLE
Randall M Chesnut, Nancy Temkin, Walter Videtta, James Pridgeon, Stephen Sulzbacher, Silvia Lujan, Luis Moya-Barquín, Kelley Chaddock, Robert H Bonow, Gustavo Petroni, Nahuel Guadagnoli, Peter Hendrickson
No abstract text is available yet for this article.
March 12, 2024: Neurosurgery
https://read.qxmd.com/read/38470124/letter-protocol-for-a-randomized-trial-comparing-intracranial-pressure-monitor-based-management-of-severe-pediatric-traumatic-brain-injury-with-management-based-on-imaging-and-clinical-examination-without-intracranial-pressure-monitoring
#25
JOURNAL ARTICLE
Katie R Nielsen, Paula Caporal, Franco Díaz, Sebastián González-Dambrauskas, Pablo Vásquez-Hoyos, Jesús Domínguez-Rojas
No abstract text is available yet for this article.
March 12, 2024: Neurosurgery
https://read.qxmd.com/read/38468544/neurovascular-coupling-in-acutely-concussed-adolescent-patients
#26
JOURNAL ARTICLE
Patricia Roby, Anne E Mozel, Matthew F Grady, Tina Master, Kristy B Arbogast
Neurovascular coupling (NVC) uniquely describes cerebrovascular response to neural activation and has demonstrated impairments following concussion in adult patients. It is currently unclear how adolescent patients experience impaired neurovascular coupling acutely following concussion during this dynamic phase of physiological development. The purpose of this study was to investigate NVC in acutely concussed adolescent patients relative to controls. We recruited patients presenting to a sports medicine practice within 28 days of a concussion or a musculoskeletal injury (controls)...
March 12, 2024: Journal of Neurotrauma
https://read.qxmd.com/read/38468511/head-injury-treatment-with-healthy-and-advanced-dietary-supplements-hit-heads-a-pilot-randomized-controlled-trial-of-the-tolerability-safety-and-efficacy-of-branched-chain-amino-acids-bcaas-in-the-treatment-of-concussion-in-adolescents-and-young-adults
#27
JOURNAL ARTICLE
Daniel J Corwin, Sage R Myers, Kristy B Arbogast, Miranda M Lim, Jonathan E Elliott, Kristina B Metzger, Peter LeRoux, Jaclynn Elkind, Hannah Metheny, Jeffrey Berg, Kevin Pettijohn, Christina Master, Matthew P Kirschen, Akiva Cohen
Concussion is a common injury in the adolescent and young adult populations. While branched chain amino acid (BCAA) supplementation has shown improvements in neurocognitive and sleep function in pre-clinical animal models of mild to moderate traumatic brain injury (TBI), to date, no studies have been performed evaluating the efficacy of BCAAs in concussed adolescents and young adults. The goal of this pilot trial was to determine the efficacy, tolerability, and safety of varied doses of oral branched chain amino acid (BCAA) supplementation in a group of concussed adolescents and young adults...
March 12, 2024: Journal of Neurotrauma
https://read.qxmd.com/read/38464893/the-neurological-wake-up-test-in-severe-pediatric-traumatic-brain-injury-a-long-term-single-center-experience
#28
JOURNAL ARTICLE
Hilde D Mulder, Jelte Helfferich, Martin C J Kneyber
OBJECTIVES: To describe the use and outcomes of the neurological wake-up test (NWT) in pediatric severe traumatic brain injury (pTBI). DESIGN: Retrospective single-center observational cohort study. SETTING: Medical-surgical tertiary pediatric intensive care unit (PICU) in a university medical center and Level 1 Trauma Center. PATIENTS: Children younger than 18 years with severe TBI [i.e., Glasgow Coma Scale (GCS) of ≤8] admitted between January 2010 and December 2020...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38460465/patient-centered-mild-traumatic-brain-injury-interventions-in-the-emergency-department
#29
REVIEW
Sarah Ray, Jude Luke, Natalie Kreitzer
INTRODUCTION: Traumatic brain injury (TBI) results in 2.5 million emergency department (ED) visits per year in the US, with mild traumatic brain injury (mTBI) accounting for 90% of cases. There is considerable evidence that many experience chronic symptoms months to years later. This population is rarely represented in interventional studies. Management of adult mTBI in the ED has remained unchanged, without consensus of therapeutic options. The aim of this review was to synthesize existing literature of patient-centered ED treatments for adults who sustain an mTBI, and to identify practices that may offer promise...
March 5, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38457794/capillary-blood-protein-markers-of-posttraumatic-headache-in-children-after-concussion
#30
JOURNAL ARTICLE
Feiven Fan, Franz E Babl, Ella E K Swaney, Stephen J C Hearps, Michael Takagi, Samantha J Emery-Corbin, Laura F Dagley, Jumana Yousef, Georgia M Parkin, Vanessa C Rausa, Nicholas Anderson, Fabian Fabiano, Kevin Dunne, Marc Seal, Gavin A Davis, Chantal Attard, Vicki Anderson, Vera Ignjatovic
OBJECTIVE: Posttraumatic headache (PTH) represents the most common acute and persistent symptom in children after concussion, yet there is no blood protein signature to stratify the risk of PTH after concussion to facilitate early intervention. This discovery study aimed to identify capillary blood protein markers, at emergency department (ED) presentation within 48 hours of concussion, to predict children at risk of persisting PTH at 2 weeks postinjury. METHODS: Capillary blood was collected using the Mitra Clamshell device from children aged 8-17 years who presented to the ED of the Royal Children's Hospital, Melbourne, Australia, within 48 hours of sustaining a concussion...
March 8, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38457314/do-preinjury-life-events-moderate-the-outcomes-of-mild-traumatic-brain-injuries-in-children-an-a-cap-study
#31
JOURNAL ARTICLE
Safira Dharsee, Ken Tang, Miriam H Beauchamp, William Craig, Quynh Doan, Stephen B Freedman, Jocelyn Gravel, Roger Zemek, Keith Owen Yeates
OBJECTIVE: To examine preinjury life events as moderators of postconcussive symptoms (PCS) and quality of life (QoL) in children with pediatric mild traumatic brain injury (mTBI) versus orthopedic injury (OI). METHODS: Participants were 633 children with mTBI and 334 with OI, ages 8-16.99, recruited from 5 pediatric emergency departments and followed for 6 months postinjury as part of a prospective cohort study. Preinjury life events were measured retrospectively using the Child and Adolescent Survey of Experiences, PCS using the Health and Behavior Inventory (HBI) and Post-Concussion Symptom Interview (PCS-I), and QoL using the Pediatric Quality of Life Inventory (PedsQL)...
March 8, 2024: Journal of Pediatric Psychology
https://read.qxmd.com/read/38452881/screening-for-delirium-during-pediatric-brain-injury-rehabilitation
#32
JOURNAL ARTICLE
William D Watson, Hsuan-Wei Chen, Ana K Ortiz, Adrian M Svingos, Stacy J Suskauer, Sudhin A Shah, Chani Traube
OBJECTIVE: To assess feasibility of routine delirium screening using the Cornell Assessment of Pediatric Delirium (CAPD) in children admitted for rehabilitation with acquired brain injury (ABI), report on the prevalence of positive delirium screens in this population, and explore longitudinal trends in CAPD scores and their association with rehabilitation outcomes. DESIGN: Retrospective study. SETTING: Pediatric inpatient rehabilitation unit...
March 5, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38450641/pediatric-spastic-wrist-contractures-can-be-well-managed-with-wrist-arthrodesis
#33
JOURNAL ARTICLE
Megan Cain, Paige Lemhouse, Cathleen Buckon, Krister P Freese
BACKGROUND: Severe spastic wrist contractures secondary to cerebral palsy (CP) or alike can have significant implications for patient hand function, hygiene, skin breakdown, and cosmesis. When these contractures become rigid, soft tissue procedures alone are unable to obtain or maintain the desired correction. In these patients' wrist arthrodesis is an option-enabling the hand to be stabilized in a more functional position for hygiene, dressing, and general cosmesis, though are patients satisfied? METHODS: All children who had undergone a wrist arthrodesis for the management of a severe wrist contracture at Shriners Hospital, Portland between January 2016 and January 2021 were identified (n=23)...
March 7, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38450564/the-australian-traumatic-brain-injury-initiative-systematic-review-and-consensus-process-to-determine-the-predictive-value-of-pre-existing-health-conditions-for-people-with-moderate-severe-traumatic-brain-injury
#34
JOURNAL ARTICLE
Ana Antonic-Baker, Clarissa Auvrez, Gerard Tao, Matthew Bagg, Adelle Gadowski, Ancelin McKimmie, Amelia Hicks, Regina Hill, Lorena Romero, Jennie Ponsford, Natasha A Lannin, Belinda Gabbe, Peter Cameron, D James Cooper, Nick Rushworth, Melinda Fitzgerald, Terence J O'Brien
The first aim of the Australian Traumatic Brain Injury Initiative (AUS-TBI) encompasses development of a set of measures that comprehensively predict outcomes for people with moderate-severe TBI across Australia. This process engaged diverse stakeholders and information sources across six areas: social, health, and clinical factors, biological markers, treatments, and longer-term outcomes. Here, we report the systematic review of pre-existing health conditions as predictors of outcome for people with moderate-severe TBI...
March 7, 2024: Journal of Neurotrauma
https://read.qxmd.com/read/38441083/improving-post-concussion-discharge-education-for-families-seeking-emergency-department-care-intervention-development
#35
JOURNAL ARTICLE
Emily Kroshus, Mary Kathleen Steiner, Sara P D Chrisman, K Casey Lion, Frederick Rivara, Sarah J Lowry, Bonnie Strelitz, Eileen J Klein
BACKGROUND: Pediatric emergency departments (ED) are where many families receive post-concussion medical care and thus an important context for helping parents build skills to support their child after discharge. OBJECTIVE: Develop a strategy for increasing parent provision of emotional and instrumental support to their child after discharge and conduct a pilot test of this strategy's acceptability. METHODS: In a large pediatric ED in the United States, we partnered with parents ( n  = 15) and clinicians ( n  = 15) to understand needs and constraints related to discharge education and to operationalize a strategy to feasibly address these needs...
March 5, 2024: Brain Injury
https://read.qxmd.com/read/38440801/socioemotional-and-psychological-outcomes-of-hypoxic-ischemic-encephalopathy-a-systematic-review
#36
JOURNAL ARTICLE
Grace H Kromm, Hilary Patankar, Shubang Nagalotimath, Hilary Wong, Topun Austin
BACKGROUND AND OBJECTIVES: Therapeutic hypothermia has reduced the risk of death or major disability following perinatal hypoxic-ischemic encephalopathy (HIE); however, many children who experience perinatal HIE still go on to develop personal and behavioral challenges, which can be difficult for caregivers and a public health burden for society. Our objective with this review is to systematically identify and synthesize studies that evaluate associations between perinatal HIE and socioemotional or psychological outcomes...
March 5, 2024: Pediatrics
https://read.qxmd.com/read/38440335/dyke-davidoff-masson-a-case-report
#37
Boumeriem Khaoula, Bourekba Iliass, Allali Nazik, Chat Latifa, El Haddad Siham
Dyke Davidoff-Masson syndrome is a rare neurological condition that results from brain injury during early childhood stages. The precise incidence of this condition is unknown, with a slight male predominance, and adult forms have been documented. Imaging findings reveal hemisphere atrophy along with ipsilateral compensatory skull changes and hyper-pneumatization of mastoid cells. The treatment approach involves anti-epileptic medications and hemispherectomy is reserved for cases with intractable seizures. This case report delineates the clinical manifestation and therapeutic approach employed in an 8-year-old male patient exhibiting pharmaco-resistant left hemi-body convulsive seizures...
2024: Global Pediatric Health
https://read.qxmd.com/read/38436317/-effects-of-%C3%AE-1-antitrypsin-on-motor-function-in-mice-with-immature-brain-white-matter-injury
#38
JOURNAL ARTICLE
Wen-Dong Li, Juan Song, Han Zhang, Lu-Xiang Yang, Yu-Yang Yue, Xin-Ling Zhang, Yong Wang
OBJECTIVES: To investigate the effects of α1-antitrypsin (AAT) on motor function in adult mice with immature brain white matter injury. METHODS: Five-day-old C57BL/6J mice were randomly assigned to the sham surgery group ( n =27), hypoxia-ischemia (HI) + saline group ( n =27), and HI+AAT group ( n =27). The HI white matter injury mouse model was established using HI methods. The HI+AAT group received intraperitoneal injections of AAT (50 mg/kg) 24 hours before HI, immediately after HI, and 72 hours after HI; the HI+saline group received intraperitoneal injections of the same volume of saline at the corresponding time points...
February 15, 2024: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/38433348/the-etiology-diagnostics-and-treatment-of-the-spasm-of-the-near-reflex-a-narrative-review
#39
REVIEW
Michalina Szczęśniak, Ewa Sikorska, Martyna Rajca, Mateusz Koper, Wojciech Kopacz, Piotr Sikorski, Piotr Maciejewicz, Kaja Kasarełło
Physiological adaptation of the eye to the visual perception of near objects consists of the "near triad": convergence, accommodation, and pupil miosis. Normally, these tend to revert when one stops fixating on a near object. Spasm of the near reflex (SNR) is a pathological phenomenon, which manifests itself by the persistence of the above-mentioned adjustments, which prevents the eye from returning to its relaxed state. In this narrative review, we aim to summarize the etiology, diagnostics, treatment, and prevention of SNR...
March 3, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38430714/unmet-health-care-needs-over-the-first-2-years-after-pediatric-traumatic-brain-injury
#40
JOURNAL ARTICLE
Hilde Margrete Dahl, Ingvil Laberg Holthe, Nada Andelic, Marianne Løvstad, Mia C Myhre
AIM: Few studies have addressed how children and adolescents with traumatic brain injuries (TBIs) access health care and educational services. This study aimed to investigate the course of symptoms during the first two years after TBI, whether symptoms implied a need for health care and/or educational services, and the extent of unmet needs. The association between unmet needs and health-related quality of life was also explored. METHODS: This prospective cohort study was conducted at Oslo University Hospital, Norway, from 2015 to 2018...
February 7, 2024: European Journal of Paediatric Neurology: EJPN
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