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Breast MRI mammography tomosynthesis

Julie E Weiss, Martha Goodrich, Kimberly A Harris, Rachael E Chicoine, Marie B Synnestvedt, Steve J Pyle, Jane S Chen, Sally D Herschorn, Elisabeth F Beaber, Jennifer S Haas, Anna N A Tosteson, Tracy Onega
PURPOSE: To assess indication for examination for four breast imaging modalities and describe the complexity and heterogeneity of data sources and ascertainment methods. METHODS: Indication was evaluated among the Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) breast cancer research centers (PRCs). Indication data were reported overall and separately for four breast imaging modalities: digital mammography (DM), digital breast tomosynthesis (DBT), ultrasound (US), and magnetic resonance imaging (MRI)...
October 12, 2016: Journal of the American College of Radiology: JACR
M Funke
Advances in imaging of the female breast have substantially influenced the diagnosis and probably also the therapy and prognosis of breast cancer in the past few years. This article gives an overview of the most important imaging modalities in the diagnosis of breast cancer. Digital mammography is considered to be the gold standard for the early detection of breast cancer. Digital breast tomosynthesis can increase the diagnostic accuracy of mammography and is used for the assessment of equivocal or suspicious mammography findings...
October 2016: Der Radiologe
Giovanna Mariscotti, Paolo Belli, Daniela Bernardi, Beniamino Brancato, Massimo Calabrese, Luca A Carbonaro, Beatrice Cavallo-Marincola, Francesca Caumo, Paola Clauser, Laura Martinchich, Stefania Montemezzi, Pietro Panizza, Federica Pediconi, Alberto Tagliafico, Rubina M Trimboli, Chiara Zuiani, Francesco Sardanelli
Women who underwent chest radiation therapy (CRT) during pediatric/young-adult age (typically, lymphoma survivors) have an increased breast cancer risk, in particular for high doses. The cumulative incidence from 40 to 45 years of age is 13-20 %, similar to that of BRCA mutation carriers for whom contrast-enhanced magnetic resonance imaging (MRI) is recommended. However, in women who underwent CRT, MRI sensitivity is lower (63-80 %) and that of mammography higher (67-70 %) than those observed in women with hereditary predisposition, due to a higher incidence of ductal carcinoma in situ with microcalcifications and low neoangiogenesis...
July 12, 2016: La Radiologia Medica
Yiming Gao, Neeti R Bagadiya, Meghan L Jardon, Samantha L Heller, Amy N Melsaether, Hildegard B Toth, Linda Moy
OBJECTIVE: MRI-guided needle localization allows access to MRI-detected mammographically occult breast lesions that are not amenable to MRI-guided biopsy. The purpose of this study was to examine the safety and outcomes of MRI-guided needle localization. MATERIALS AND METHODS: Ninety-nine consecutive breast lesions that underwent preoperative MRI-guided needle localization were identified. Clinical indications for breast MRI, reasons for performing MRI-guided needle localization, and surgical pathology results were recorded...
September 2016: AJR. American Journal of Roentgenology
Nehmat Houssami, Kristina Lång, Daniela Bernardi, Alberto Tagliafico, Sophia Zackrisson, Per Skaane
This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trials that performed standard (2D) digital mammography (DM) and tomosynthesis (3D-mammography) in the same screening participants...
April 2016: Breast: Official Journal of the European Society of Mastology
Andrew B Rosenkrantz, Vinay Prabhu
OBJECTIVE: The objective of this study was to identify geographic and temporal patterns related to the frequencies of online searches within the United States for information on imaging-based cancer screening tests. MATERIALS AND METHODS: Google Trends, a web-based tool for identifying the frequency of online searches, was used to determine, on both a monthly and a geographic basis, the relative frequency of searches for imaging-based cancer screening tests in the United States from 2004 through 2014...
January 2016: AJR. American Journal of Roentgenology
Sanjay Warrier, Grace Tapia, David Goltsman, Jane Beith
This article provides an overview of the main controversies in a number of key areas of breast cancer management. Relevant studies that have contributed to guide the treatment of this heterogeneous disease in the field of breast screening, surgery, chemotherapy and radiotherapy are highlighted. Mammography and ultrasound are the main methods of breast screening. MRI and tomosynthesis are emerging as new screening tools for a selected group of breast cancer patients. From a surgical perspective, oncoplastic techniques and neoadjuvant chemotherapy are improving cosmetic results in breast-conserving surgery...
2016: Women's Health
Dragana Roganovic, Dragana Djilas, Sasa Vujnovic, Dag Pavic, Dragan Stojanov
Breast cancer is the most common malignancy in women and early detection is important for its successful treatment. The aim of this study was to investigate the sensitivity and specificity of three methods for early detection of breast cancer: breast magnetic resonance imaging (MRI), digital mammography, and breast tomosynthesis in comparison to histopathology, as well as to investigate the intraindividual variability between these modalities. We included 57 breast lesions, each detected by three diagnostic modalities: digital mammography, breast MRI, and breast tomosynthesis, and subsequently confirmed by histopathology...
November 16, 2015: Bosnian Journal of Basic Medical Sciences
F Chamming's, J Chopier, C Mathelin, E Chéreau
OBJECTIVES: To assess imaging performances for the detection, characterization and biopsy of breast microcalcifications and make recommendations. MATERIALS AND METHODS: French and English publications were searched using PubMed, Cochrane Library and international learned societies recommendations. RESULTS: Digital mammography (DR [Direct Radiography] and CR [Computed Radiography]) and screen-film mammography demonstrate good performances for the detection and the characterization of breast microcalcifications...
December 2015: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Chen-Pin Chou, John M Lewin, Chia-Ling Chiang, Bao-Hui Hung, Tsung-Lung Yang, Jer-Shyung Huang, Jia-Bin Liao, Huay-Ben Pan
PURPOSE: To compare the diagnostic accuracy of contrast-enhanced digital mammography (CEDM) and contrast-enhanced tomosynthesis (CET) to dynamic contrast enhanced breast MRI (DCE-MRI) using a multireader-multicase study. METHODS: Institutional review board approval and informed consents were obtained. Total 185 patients (mean age 51.3) with BI-RADS 4 or 5 lesions were evaluated before biopsy with mammography, tomosynthesis, CEDM, CET and DCE-MRI. Mediolateral-oblique and cranio-caudal views of the target breast CEDM and CET were acquired at 2 and 4 min after contrast agent injection...
December 2015: European Journal of Radiology
Teresa G Odle
Artifacts appear on breast images for a number of reasons. Radiologic technologists play an important role in identifying artifacts that can help or hinder breast cancer diagnosis and in minimizing artifacts that degrade image quality. This article describes various artifacts that occur in breast imaging, along with their causes. The article focuses on artifacts in mammography, with a heavy emphasis on digital mammography, and on magnetic resonance imaging of the breast. Artifacts in ultrasonography of the breast, digital breast tomosynthesis, and positron emission mammography also are discussed...
September 2015: Radiologic Technology
Won Hwa Kim, Jung Min Chang, Hyeong-Gon Moon, Ann Yi, Hye Ryoung Koo, Hye Mi Gweon, Woo Kyung Moon
OBJECTIVES: To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. METHODS: Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used...
June 2016: European Radiology
Kyung Jin Nam, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Eun Young Ko, Dong Wook Jeong, Ki Seok Choo
OBJECTIVE: To determine what percentage of cancers, detected by screening ultrasonography (US), were detectable by full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT). MATERIALS AND METHODS: Eighty-four consecutive women in whom mammography was negatively interpreted and supplementary screening US initially detected breast cancers at outside hospitals underwent both FFDM and DBT. We excluded cases with overt suspicious findings on repeat mammography and ineligible cases...
October 2015: Breast: Official Journal of the European Society of Mastology
D Arefan, A Talebpour, N Ahmadinejhad, A Kamali Asl
Digital Breast Tomosynthesis (DBT) is a technology that creates three dimensional (3D) images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study ultra-fast image reconstruction technique for Tomosynthesis Mammography systems using Graphics Processing Unit (GPU)...
June 2015: Journal of Biomedical Physics & Engineering
Kimberly M Ray, Estella Turner, Edward A Sickles, Bonnie N Joe
To review the imaging and pathologic features of a series of lesions detected at digital breast tomosynthesis (DBT), which are occult to conventional digital mammography (DM). We retrospectively reviewed 268 consecutive breast imaging reporting and data system 4 and 5 lesions imaged with both DM and DBT at our facility from July 2012 through April 2013. For each lesion, we recorded the mammographic finding, breast density, mode of biopsy, and pathology results. A total of 19 lesions were identified at DBT that were occult to DM...
September 2015: Breast Journal
Alison Chetlen, Julie Mack, Tiffany Chan
Mammographic screening is effective in reducing mortality from breast cancer. The issue is not whether mammography is effective, but whether the false positive rate and false negative rates can be reduced. This review will discuss controversies including the reduction in breast cancer mortality, overdiagnosis, the ideal screening candidate, and the optimal imaging modality for breast cancer screening. The article will compare and contrast screening mammography, tomosynthesis, whole-breast screening ultrasound, magnetic resonance imaging, and molecular breast imaging...
March 2016: Clinical Imaging
C Kaniklidis
After some decades of contention, one can almost despair and conclude that (paraphrasing) "the mammography debate you will have with you always." Against that sentiment, in this review I argue, after reflecting on some of the major themes of this long-standing debate, that we must begin to move beyond the narrow borders of claim and counterclaim to seek consensus on what the balance of methodologically sound and critically appraised evidence demonstrates, and also to find overlooked underlying convergences; after acknowledging the reality of some residual and non-trivial harms from mammography, to promote effective strategies for harm mitigation; and to encourage deployment of new screening modalities that will render many of the issues and concerns in the debate obsolete...
June 2015: Current Oncology
Paola Clauser, Luca A Carbonaro, Martina Pancot, Rossano Girometti, Massimo Bazzocchi, Chiara Zuiani, Francesco Sardanelli
OBJECTIVES: To evaluate second-look digital breast tomosynthesis (SL-DBT) for additional findings (AFs) at preoperative MRI compared with second-look ultrasound (SL-US). METHODS: We included 135 patients with breast cancer who underwent digital mammography (DM), DBT, US, and MRI at two centres. MR images were retrospectively evaluated to find AFs, described as focus, mass, or non-mass; ≤10 mm or >10 mm in size; BI-RADS 3, 4, or 5. DM and DBT exams were reviewed looking for MRI AFs; data on SL-US were collected...
October 2015: European Radiology
Wei Tang, Wei Jun Peng, Ya Jia Gu, Hui Zhu, Ting Ting Jiang, Can Li
OBJECTIVE: This study aimed to describe the imaging features of adenoid cystic carcinoma (ACC) of the breast using multimode imaging. MATERIALS AND METHODS: The findings from mammography, sonography, magnetic resonance imaging, or digital breast tomosynthesis in 11 patients with histopathologically confirmed ACC of the breast were reviewed. The imaging criteria included location, shape, size, number, margin, calcification, attenuation, echo and/or signal intensity, internal mass enhancement pattern, and dynamic-enhancement characteristics...
July 2015: Journal of Computer Assisted Tomography
Giovanna Mariscotti, Nehmat Houssami, Manuela Durando, Pier Paolo Campanino, Elisa Regini, Alberto Fornari, Riccardo Bussone, Isabella Castellano, Anna Sapino, Paolo Fonio, Giovanni Gandini
OBJECTIVES: Preoperative breast magnetic resonance (MR) often generates additional suspicious findings needing further investigations. Targeted breast ultrasound (US) is the standard tool to characterize MR additional lesions. The purpose of this study is to evaluate the potential role of digital breast tomosynthesis (DBT) to characterize MR detected additional findings, unidentified at targeted breast US. METHODS: This prospective study included women who a) had biopsy-proven, newly diagnosed breast cancers detected at conventional 2D mammography and/or US, referred to breast MR for tumour staging; and b) had DBT if additional MR findings were not detected at targeted ('second look') US...
September 2015: European Radiology
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