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https://www.readbyqxmd.com/read/28920809/evaluation-of-bone-mineralization-by-computed-tomography-in-wild-and-captive-european-common-spadefoots-pelobates-fuscus-in-relation-to-exposure-to-ultraviolet-b-radiation-and-dietary-supplements
#1
Martine van Zijll Langhout, Richard P J H Struijk, Tessa Könning, Dick van Zuilen, Katalin Horvath, Hester van Bolhuis, Roelof Maarschalkerweerd, Frank Verstappen
Captive rearing programs have been initiated to save the European common spadefoot (Pelobates fuscus), a toad species in the family of Pelobatidae, from extinction in The Netherlands. Evaluating whether this species needs ultraviolet B (UVB) radiation and/or dietary supplementation for healthy bone development is crucial for its captive management and related conservation efforts. The bone mineralization in the femurs and the thickest part of the parietal bone of the skulls of European common spadefoots (n = 51) was measured in Hounsfield units (HUs) by computed tomography...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28918582/removal-of-endrin-and-dieldrin-isomeric-pesticides-through-stereoselective-adsorption-behavior-on-the-graphene-oxide-magnetic-nanoparticles
#2
Kamlesh Shrivas, Archana Ghosale, Nidhi Nirmalkar, Arti Srivastava, Sunil Kumar Singh, Sandip S Shinde
A novel stereoselective removal behavior of isomeric endrin and dieldrin pesticides from sample solution is demonstrated using nanocomposite of graphene oxide (GO) and iron oxide (Fe3O4) magnetic nanoparticles (MNPs). The removal efficiency of endrin and dieldrin was found higher when GO-MNPs was used as a separating probe than the individual use of GO and MNPs. The removal efficiency of both the pesticides was found to be more favorable when the dosage amount of GO-MNPs was 30 mg for 30-min contact time with pH 4...
September 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28918439/the-gulf-oil-spill-miscarriage-and-infertility-the-growh-study
#3
Emily W Harville, Arti Shankar, Leah Zilversmit, Pierre Buekens
PURPOSE: To examine whether reported exposure to the Gulf oil spill (2010) was related to reproductive reported miscarriage or infertility. METHODS: 1524 women aged 18-45 recruited through prenatal and Women, Infant, and Children (WIC) clinics, and community events were interviewed about their experience of the oil spill and reproductive history. 1434 women had information on outcomes of at least one pregnancy, and 633 on a pregnancy both before and after the spill...
September 16, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28914366/geriatric-assessment-with-management-intervention-in-older-adults-with-cancer-a-randomized-pilot-study
#4
Allison Magnuson, Tatyana Lemelman, Chintan Pandya, Molly Goodman, Marcus Noel, Mohammed Tejani, David Doughtery, William Dale, Arti Hurria, Michelle Janelsins, Feng Vankee Lin, Charles Heckler, Supriya Mohile
BACKGROUND: Older adults receiving cancer therapy have heightened risk for treatment-related toxicity. Geriatric assessment (GA) can identify impairments, which may contribute to vulnerability and adverse outcomes. GA management interventions can address these impairments and have the potential to improve outcomes when implemented. METHODS: We conducted a randomized pilot study comparing GA with management interventions versus usual care in patients with stage III/IV solid tumor malignancies (N = 71)...
September 15, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28913655/quantitative-trait-loci-for-resistance-to-stripe-rust-of-wheat-revealed-using-global-field-nurseries-and-opportunities-for-stacking-resistance-genes
#5
Firdissa E Bokore, Richard D Cuthbert, Ron E Knox, Harpinder S Randhawa, Colin W Hiebert, Ron M DePauw, Asheesh K Singh, Arti Singh, Andrew G Sharpe, Amidou N'Diaye, Curtis J Pozniak, Curt McCartney, Yuefeng Ruan, Samia Berraies, Brad Meyer, Catherine Munro, Andy Hay, Karim Ammar, Julio Huerta-Espino, Sridhar Bhavani
Quantitative trait loci controlling stripe rust resistance were identified in adapted Canadian spring wheat cultivars providing opportunity for breeders to stack loci using marker-assisted breeding. Stripe rust or yellow rust, caused by Puccinia striiformis Westend. f. sp. tritici Erikss., is a devastating disease of common wheat (Triticum aestivum L.) in many regions of the world. The objectives of this research were to identify and map quantitative trait loci (QTL) associated with stripe rust resistance in adapted Canadian spring wheat cultivars that are effective globally, and investigate opportunities for stacking resistance...
September 14, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28902842/the-neuropeptide-nmu-amplifies-ilc2-driven-allergic-lung-inflammation
#6
Antonia Wallrapp, Samantha J Riesenfeld, Patrick R Burkett, Raja-Elie E Abdulnour, Jackson Nyman, Danielle Dionne, Matan Hofree, Michael S Cuoco, Christopher Rodman, Daneyal Farouq, Brian J Haas, Timothy L Tickle, John J Trombetta, Pankaj Baral, Christoph S N Klose, Tanel Mahlakõiv, David Artis, Orit Rozenblatt-Rosen, Isaac M Chiu, Bruce D Levy, Monika S Kowalczyk, Aviv Regev, Vijay K Kuchroo
Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote homeostasis versus inflammation are unclear. To identify such molecular cues, we profiled mouse lung-resident ILCs using single-cell RNA sequencing at steady state and after in vivo stimulation with the alarmin cytokines IL-25 and IL-33. ILC2s were transcriptionally heterogeneous after activation, with subpopulations distinguished by expression of proliferative, homeostatic and effector genes...
September 13, 2017: Nature
https://www.readbyqxmd.com/read/28892887/active-surveillance-of-health-care-associated-infections-in-neurosurgical-patients
#7
Reshu Agarwal, Sarita Mohapatra, Girija Prasad Rath, Arti Kapil
INTRODUCTION: Health Care Associated Infections (HCAI) are frequent complications in neurosurgery. There is limited data available on the incidence and burden of HCAI in neurosurgical patients of Southeast Asian region. AIM: To identify various HCAIs, associated aetiological agents and their antimicrobial susceptibility pattern among the patients admitted in the neurosurgery unit. MATERIALS AND METHODS: An observational prospective study was carried out for three months duration on all neurosurgical patients admitted to a tertiary-care center...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889730/anti-inflammatory-and-immunomodulatory-activities-of-inula-cappa-roots-compositae
#8
Jyoti Kalola, Rahul Shah, Arti Patel, Suman K Lahiri, Mamta B Shah
Background The medicinal properties of Inula cappa, a perennial shrub, are ascribed to its roots. In this article, we study the anti-inflammatory and immunomodulatory activities of I. cappa root extracts based on its utilization in traditional medicine-treatment of rheumatoid arthritis, menoxenia, fever, jaundice and many others. Methods Anti-inflammatory and immunomodulatory activities of I. cappa extracts were studied. The anti-inflammatory activity was determined by carrageenan-induced rat paw edema and cotton pellet-induced granulation method while the immunomodulatory activity was estimated by phagocytic assay method, hemagglutinating antibody (HA) titer assay, delayed-type hypersensitivity assay method, plaque forming cell assay and determination of immunoprophylatic activity...
March 18, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28872046/racial-and-ethnic-differences-in-antibiotic-use-for-viral-illness-in-emergency-departments
#9
Monika K Goyal, Tiffani J Johnson, James M Chamberlain, T Charles Casper, Timothy Simmons, Evaline A Alessandrini, Lalit Bajaj, Robert W Grundmeier, Jeffrey S Gerber, Scott A Lorch, Elizabeth R Alpern
BACKGROUND AND OBJECTIVES: In the primary care setting, there are racial and ethnic differences in antibiotic prescribing for acute respiratory tract infections (ARTIs). Viral ARTIs are commonly diagnosed in the pediatric emergency department (PED), in which racial and ethnic differences in antibiotic prescribing have not been previously reported. We sought to investigate whether patient race and ethnicity was associated with differences in antibiotic prescribing for viral ARTIs in the PED...
September 5, 2017: Pediatrics
https://www.readbyqxmd.com/read/28869965/the-neuropeptide-neuromedin-u-stimulates-innate-lymphoid-cells-and-type-2-inflammation
#10
Christoph S N Klose, Tanel Mahlakõiv, Jesper B Moeller, Lucille C Rankin, Anne-Laure Flamar, Hiroki Kabata, Laurel A Monticelli, Saya Moriyama, Gregory Garbès Putzel, Nikolai Rakhilin, Xiling Shen, Evi Kostenis, Gabriele M König, Takashi Senda, Dustin Carpenter, Donna L Farber, David Artis
The type 2 cytokines interleukin (IL)-4, IL-5, IL-9 and IL-13 have important roles in stimulating innate and adaptive immune responses that are required for resistance to helminth infection, promotion of allergic inflammation, metabolic homeostasis and tissue repair. Group 2 innate lymphoid cells (ILC2s) produce type 2 cytokines, and although advances have been made in understanding the cytokine milieu that promotes ILC2 responses, how ILC2 responses are regulated by other stimuli remains poorly understood...
September 14, 2017: Nature
https://www.readbyqxmd.com/read/28868509/-targeted-prophylaxis-impact-of-rectal-swab-culture-directed-prophylaxis-on-infectious-complications-after-transrectal-ultrasound-guided-prostate-biopsy
#11
Prabhjot Singh, Ashish Kumar, Siddharth Yadav, Lok Prakash, Brusabhanu Nayak, Rajeev Kumar, Arti Kapil, Prem Nath Dogra
PURPOSE: To assess the prevalence of fluoroquinolone resistance among patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy and the impact of rectal swab culture-directed antibiotic prophylaxis on postbiopsy infectious complications. MATERIALS AND METHODS: We prospectively analyzed all patients undergoing TRUS-guided prostate biopsy from April 2013 to February 2015. Antibiotic prophylaxis was tailored to the results of rectal swab cultures. If the organism was fluoroquinolone-sensitive, oral ciprofloxacin 500 mg with tinidazole 600 mg was prescribed...
September 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28861397/modulation-of-host-immunity-by-human-respiratory-syncytial-virus-virulence-factors-a-synergic-inhibition-of-both-innate-and-adaptive-immunity
#12
REVIEW
Gisela Canedo-Marroquín, Orlando Acevedo-Acevedo, Emma Rey-Jurado, Juan M Saavedra, Margarita K Lay, Susan M Bueno, Claudia A Riedel, Alexis M Kalergis
The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide. Symptoms of hRSV infection include bronchiolitis and pneumonia. The lung pathology observed during hRSV infection is due in part to an exacerbated host immune response, characterized by immune cell infiltration to the lungs. HRSV is an enveloped virus, a member of the Pneumoviridae family, with a non-segmented genome and negative polarity-single RNA that contains 10 genes encoding for 11 proteins...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28860531/ultra-broad-mid-ir-supercontinuum-generation-in-single-bi-and-tri-layer-graphene-nano-plasmonic-waveguides-pumping-at-low-input-peak-powers
#13
Swetha S Bobba, Arti Agrawal
This article presents four different plasmonic structures using Graphene which yielded an efficient plasmonic mode with low loss for Supercontinuum(SC) generation. At an operating wavelength of 1550 nm in these structures, we generated a multi-octave broadband SC spectrum ranging from 1.5 um-25 um at a low input peak power of 1 W. Due to pumping in the anomalous dispersion region with two Zero Dispersion Wavelengths (ZDWs) and the process of cross phase modulation with soliton fission, red-shifted dispersive waves were generated which led to large broadening from 1...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28857226/virtual-glucose-management-service-a-novel-resident-educational-tool
#14
Joshua A Rushakoff, Zachary Kornberg, Arti D Shah, Robert J Rushakoff
No abstract text is available yet for this article.
August 30, 2017: Medical Education
https://www.readbyqxmd.com/read/28851415/association-of-pre-chemotherapy-peripheral-blood-pro-inflammatory-and-coagulation-factors-with-reduced-relative-dose-intensity-in-women-with-breast-cancer
#15
Yuan Yuan, Nilesh Vora, Can-Lan Sun, Daneng Li, Enrique Soto-Perez-de-Celis, Joanne Mortimer, The-Hang Luu, George Somlo, James Waisman, David Smith, Joseph Chao, Vani Katheria, Timothy Synold, Vivi Tran, Shu Mi, Abrahm Levi, Anait Arsenyan, Jennifer Choi, Laura Zavala, Susan Yost, Arti Hurria
BACKGROUND: Chemotherapy decreases the risk of relapse and mortality in early-stage breast cancer (BC), but it comes with the risk of toxicity. Chemotherapy efficacy depends on relative dose intensity (RDI), and an RDI < 85% is associated with worse overall survival. The pro-inflammatory (interleukin (IL)-6, C-reactive protein (CRP)) and coagulation factors (D-dimer) serve as biomarkers of aging. The purpose of this study is to determine if these biomarkers are associated with reduced RDI in women with stage I-III BC...
August 29, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28837375/hematology-oncology-fellows-training-in-geriatrics-and-geriatric-oncology-findings-from-an-american-society-of-clinical-oncology-sponsored-national-survey
#16
Ronald J Maggiore, William Dale, Arti Hurria, Heidi D Klepin, Andrew Chapman, Efrat Dotan, Supriya G Mohile, Arash Naeim, Ajeet Gajra, Mary K Buss
PURPOSE: Older adults compose the majority of patients with cancer in the United States; however, it is unclear how well geriatrics or geriatric oncology training is being incorporated into hematology-oncology (hem-onc) fellowships. METHODS: A convenience sample of hem-onc fellows completed a (written or electronic) survey assessing their education, clinical experiences, and perceived proficiency in geriatric oncology during training; knowledge base in geriatric oncology; confidence in managing older adults with cancer; and general attitudes toward geriatric oncology principles...
August 24, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28836065/a-multi-stage-genome-wide-association-study-of-uterine-fibroids-in-african-americans
#17
Jacklyn N Hellwege, Janina M Jeff, Lauren A Wise, C Scott Gallagher, Melissa Wellons, Katherine E Hartmann, Sarah F Jones, Eric S Torstenson, Scott Dickinson, Edward A Ruiz-Narváez, Nadin Rohland, Alexander Allen, David Reich, Arti Tandon, Bogdan Pasaniuc, Nicholas Mancuso, Hae Kyung Im, David A Hinds, Julie R Palmer, Lynn Rosenberg, Joshua C Denny, Dan M Roden, Elizabeth A Stewart, Cynthia C Morton, Eimear E Kenny, Todd L Edwards, Digna R Velez Edwards
Uterine fibroids are benign tumors of the uterus affecting up to 77% of women by menopause. They are the leading indication for hysterectomy, and account for $34 billion annually in the United States. Race/ethnicity and age are the strongest known risk factors. African American (AA) women have higher prevalence, earlier onset, and larger and more numerous fibroids than European American women. We conducted a multi-stage genome-wide association study (GWAS) of fibroid risk among AA women followed by in silico genetically predicted gene expression profiling of top hits...
August 23, 2017: Human Genetics
https://www.readbyqxmd.com/read/28825837/self-assembly-in-aqueous-oppositely-charged-gemini-surfactants-a-correlation-between-morphology-and-solubilization-efficacy
#18
Sneha Singh, Arti Bhadoria, Kushan Parikh, Sanjay Kumar Yadav, Sugam Kumar, Vinod Kumar Aswal, Sanjeev Kumar
Micellization behaviour of oppositely charged gemini surfactants (anionic surfactant; phosphoric acid, P, P'-1,4-butanedieyl, P,P' didodecylester, disodium salt (12-4-12A),and cationic surfactant; butanediyl-1,4, bis (N,N-hexadecyl ammonium) dibromide (16-4-16) or (D-isosorbate-1,4-diyl bis(N,N-dimethyl-N-hexadecylammonium acetoxy) dichloride (16-Isb-16)) has been studied (individually or of a gemini mixture) by conductivity and surface tension measurements. Critical micelle concentration (CMC) data show both synergistic (for 12-4-12A + 16-Isb-16) and antagonistic (for 12-4-12A + 16-4-16) interactions between the two components...
August 21, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28811040/implant-specific-follow-up-imaging-of-treated-intracranial-aneurysms-tof-mra-vs-metal-artifact-reduced-intravenous-flat-panel-computed-tomography-angiography-fpcta
#19
N H Hänsel, G A Schubert, B Scholz, O Nikoubashman, A E Othman, M Wiesmann, R Pjontek, M A Brockmann
AIM: To compare the diagnostic quality of time-of-flight magnetic resonance angiography (TOF-MRA) and metal-artefact-reduction (MAR) flat-panel-detector computed tomography angiography (FPCTA) and to determine the imaging technique best suited for evaluation endovascular and surgically treated aneurysms. METHODS: The image quality of TOF-MRA and MAR-FPCTA of 44 intracranial implants (coiling: n=20; clipping: n=15; coiling + stenting: n=9) in a patient cohort of 25 was evaluated by two independent readers...
August 12, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28808093/are-disagreements-in-caregiver-and-patient-assessment-of-patient-health-associated-with-increased-caregiver-burden-in-caregivers-of-older-adults-with-cancer
#20
Tina Hsu, Matthew Loscalzo, Rupal Ramani, Stephen Forman, Leslie Popplewell, Karen Clark, Vani Katheria, Rex Strowbridge, Redmond Rinehart, Dan Smith, Keith Matthews, Jeff Dillehunt, Tao Feng, David Smith, Canlan Sun, Arti Hurria
BACKGROUND: As patients age, caregivers increasingly provide essential support and patient information. We sought to determine if patient-caregiver assessments of patient health differ and if differences contribute to burden in caregivers of older adults with cancer. MATERIALS AND METHODS: One hundred patients, aged ≥65, and their caregivers independently assessed patient function, comorbidity, nutrition, social activity, social support, and mental health. Caregivers completed the Caregiver Strain Index (CSI)...
August 14, 2017: Oncologist
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