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https://www.readbyqxmd.com/read/27918289/a-bioreactor-with-an-electro-responsive-elastomeric-membrane-for-mimicking-intestinal-peristalsis
#1
Daniele Cei, Joana Costa, Giulia Gori, Gabriele Frediani, Claudio Domenici, Federico Carpi, Arti Ahluwalia
This study describes an actuated bioreactor which mimics the pulsatile contractile motion of the intestinal barrier using electro-responsive elastomers as smart materials that undergo deformation upon electrical stimulation. The device consists of an annular dielectric elastomer actuator working as a radial artificial muscle able to rhythmically contract and relax a central cell culture well. The bioreactor maintained up to 4 h of actuation at a frequency of 0.15 Hz and a strain of 8%-10%, to those of the cyclic contraction and relaxation of the small intestine...
December 5, 2016: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/27917181/nitric-oxide-responsive-heavy-metal-associated-gene-athmad1-contributes-to-development-and-disease-resistance-in-arabidopsis-thaliana
#2
Q Muhammad Imran, Noreen Falak, Adil Hussain, Bong-Gyu Mun, Arti Sharma, Sang-Uk Lee, Kyung-Min Kim, Byung-Wook Yun
Exposure of plants to different biotic and abiotic stress condition instigates significant change in the cellular redox status; resulting in the elevation of reactive nitrogen species that play signaling role in mediating defense responses. Heavy metal associated (HMA) domain containing genes are required for spatio-temporal transportation of metal ions that bind with various enzymes and co-factors within the cell. To uncover the underlying mechanisms mediated by AtHMA genes, we identified 14 Arabidopsis HMA genes that were differentially expressed in response to nitrosative stress through RNA-seq analysis...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27907230/reverse-geroscience-how-does-exposure-to-early-diseases-accelerate-the-age-related-decline-in-health
#3
Ronald A Kohanski, Steven G Deeks, Claudia Gravekamp, Jeffrey B Halter, Kevin High, Arti Hurria, Rebecca Fuldner, Paige Green, Robin Huebner, Francesca Macchiarini, Felipe Sierra
Aging is the major risk factor for both the development of chronic diseases and loss of functional capacity. Geroscience provides links among the biology of aging, the biology of disease, and the physiology of frailty, three fields where enormous progress has been made in the last few decades. While, previously, the focus was on the role of aging in susceptibility to disease and disability, the other side of this relationship, which is the contribution of disease to aging, has been less explored at the molecular/cellular level...
December 1, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27905672/oral-astragalus-huang-qi-for-preventing-frequent-episodes-of-acute-respiratory-tract-infection-in-children
#4
REVIEW
Guobin Su, Xiankun Chen, Zhuangzhu Liu, Lihong Yang, La Zhang, Cecilia Stålsby Lundborg, Zehuai Wen, Xinfeng Guo, Xindong Qin, Jueyao Liang, Xusheng Liu
BACKGROUND: Acute respiratory tract infections (ARTIs) are common in children and can involve both upper and lower airways. Many children experience frequent ARTI episodes or recurrent respiratory tract infections (RRTIs) in early life, which creates challenges for paediatricians, primary care physicians, parents and carers of children.In China, Astragalus (Huang qi), alone or in combination with other herbs, is used by Traditional Chinese Medicine (TCM) practitioners in the form of a water extract, to reduce the risk of ARTIs; it is believed to stimulate the immune system...
December 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27896280/genetic-hearing-loss-the-journey-of-discovery-to-destination-how-close-are-we-to-therapy
#5
Arti Pandya
No abstract text is available yet for this article.
November 2016: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/27892991/surveillance-mammography-in-older-patients-with-breast-cancer-can-we-ever-stop-a-review
#6
Rachel A Freedman, Nancy L Keating, Ann H Partridge, Hyman B Muss, Arti Hurria, Eric P Winer
Importance: Approximately 4% to 5% of breast cancer survivors will develop a new ipsilateral or contralateral cancer (in-breast event) over the 5 years following diagnosis, and annual surveillance mammography is recommended for those with residual breast tissue. The risk for such in-breast events persists over time, though increasing age at cancer diagnosis and treatment with hormonal therapy are associated with lower risk, and most older survivors of breast cancer will ultimately die from nonbreast cancer-related causes...
November 17, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/27886793/innovative-approaches-to-hypertension-control-in-low-and-middle-income-countries
#7
REVIEW
Rajesh Vedanthan, Antonio Bernabe-Ortiz, Omarys I Herasme, Rohina Joshi, Patricio Lopez-Jaramillo, Amanda G Thrift, Jacqui Webster, Ruth Webster, Karen Yeates, Joyce Gyamfi, Merina Ieremia, Claire Johnson, Jemima H Kamano, Maria Lazo-Porras, Felix Limbani, Peter Liu, Tara McCready, J Jaime Miranda, Sailesh Mohan, Olugbenga Ogedegbe, Brian Oldenburg, Bruce Ovbiagele, Mayowa Owolabi, David Peiris, Vilarmina Ponce-Lucero, Devarsetty Praveen, Arti Pillay, Jon-David Schwalm, Sheldon W Tobe, Kathy Trieu, Khalid Yusoff, Valentin Fuster
Elevated blood pressure, a major risk factor for ischemic heart disease, heart failure, and stroke, is the leading global risk for mortality. Treatment and control rates are very low in low- and middle-income countries. There is an urgent need to address this problem. The Global Alliance for Chronic Diseases sponsored research projects focus on controlling hypertension, including community engagement, salt reduction, salt substitution, task redistribution, mHealth, and fixed-dose combination therapies. This paper reviews the rationale for each approach and summarizes the experience of some of the research teams...
February 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/27875476/pacing-to-prevent-atrial-fibrillation
#8
Surendra K Chutani, Arti N Shah, Bharat K Kantharia
PURPOSE OF REVIEW: Pacemakers are frequently implanted in patients with atrial fibrillation. Many patients with pacemakers also develop atrial fibrillation. Over a period of time, through many studies on different pacing modes, sites, and algorithms, significant insights have been gained in the field of treatment and prevention of atrial fibrillation. The purpose of this review is to discuss some aspects of the scientific basis, current standards and possible future research related to cardiac pacing for prevention of atrial fibrillation...
January 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27856262/association-between-renal-function-and-chemotherapy-related-toxicity-in-older-adults-with-cancer
#9
Lindsay L Peterson, Arti Hurria, Tao Feng, Supriya G Mohile, Cynthia Owusu, Heidi D Klepin, Cary P Gross, Stuart M Lichtman, Ajeet Gajra, Ilya Glezerman, Vani Katheria, Laura Zavala, David D Smith, Can-Lan Sun, William P Tew
PURPOSE: To evaluate the association between renal function (RF) and chemotherapy-related toxicity (CRT) in older adults with cancer and to compare the effect of different RF formulas and body weight measurements on this association. METHODS: This is a secondary analysis of data from a prospective multicenter study of patients ≥ age 65 who were starting a new chemotherapy regimen. RF was estimated with 4 formulas (modified Jelliffe [Jelliffe], Cockcroft-Gault [CG], Wright, and Modification of Diet in Renal Disease [MDRD]), using actual, ideal and adjusted body weights for 492 patients...
November 14, 2016: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/27850021/381-data-communication-gaps-during-icu-rounds-on-ventilated-patients-an-important-clinical-blind-spot
#10
James Bordley, Karess McGrath, Stephanie Nonas, Vishnu Mohan, Jeffrey Gold, Kathryn Artis
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27849621/vancomycin-induced-thrombocytopenia-in-a-newborn
#11
Kunal Kalra, Hema Gupta Mittal, Arti Maria
Neonatal thrombocytopenia is common and is frequently seen in neonatal sepsis. Drug-induced thrombocytopenia is likely to be missed unless a high index of suspicion is present. Changing of antibiotics for assumed nonresolution of sepsis may lead to persistent thrombocytopenia in a neonate if drug-induced thrombocytopenia is missed. Vancomycin-induced neonatal thrombocytopenia is rarely described in scientific literature. We describe a newborn who was diagnosed with early onset sepsis and vancomycin-induced thrombocytopenia...
December 1, 2016: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/27843845/the-study-on-achievement-of-motor-milestones-and-associated-factors-among-children-in-rural-north-india
#12
Arti Gupta, Mani Kalaivani, Sanjeev Kumar Gupta, Sanjay K Rai, Baridalyne Nongkynrih
BACKGROUND: Nearly 14% of children worldwide do not reach their developmental potential in early childhood. The early identification of delays in achieving milestones is critical. The World Health Organization (WHO) has developed normal age ranges for the achievement of motor milestones by healthy children. This study aimed to assess the gross motor developmental achievements and associated factors among children in rural India. MATERIALS AND METHODS: A cross-sectional study was conducted with rural children in North India...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27843191/role-of-256-slice-mdct-in-the-evaluation-of-coronary-artery-fistula-a-case-series-with-review-of-literature
#13
Sunita Dashottar, R K Singh, S K Malani, Arti Sarin, H S Arora
No abstract text is available yet for this article.
October 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/27833338/intraoperative-computed-tomography-in-bilateral-sagittal-split-osteotomy
#14
Jimoh Olubanwo Agbaje, Ahmed Sobhy Salem, Ivo Lambrichts, Luc Daems, Paul Legrand, Constantinus Politis
OBJECTIVES: The objective of the study was to show the importance of intraoperative computed tomography as an aid for ensuring inferior alveolar nerve safety during bilateral sagittal split osteotomy. MATERIALS AND METHODS: This study included ten patients who underwent bilateral sagittal split osteotomy procedure. All patients were treated for orthognathic reasons. The unerupted lower third molars, if present, were removed at least 6 months prior to Sagittal Split Osteotomy...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27826938/using-leap-motion-to-investigate-the-emergence-of-structure-in-speech-and-language
#15
Kerem Eryilmaz, Hannah Little
 In evolutionary linguistics, experiments using artificial signal spaces are being used to investigate the emergenceof speech structure. These signal spaces need to be continuous, non-discretized spaces from which discrete unitsand patterns can emerge. They need to be dissimilar from-but comparable with-the vocal tract, in order tominimize interference from pre-existing linguistic knowledge, while informing us about language. This is a hardbalance to strike. This article outlines a new approach that uses the Leap Motion, an infrared controller that canconvert manual movement in 3d space into sound...
November 8, 2016: Behavior Research Methods
https://www.readbyqxmd.com/read/27825850/the-role-of-%C3%AE-smooth-muscle-actin-in-fibroblast-mediated-matrix-contraction-and-remodeling
#16
Arti V Shinde, Claudio Humeres, Nikolaos G Frangogiannis
Cardiac myofibroblasts play an important role in myocardial remodeling. Although α-smooth muscle actin (α-SMA) expression is the hallmark of mature myofibroblasts, its role in regulating fibroblast function remains poorly understood. We explore the effects of the matrix environment in modulating cardiac fibroblast phenotype, and we investigate the role of α-SMA in fibroblast function using loss- and gain-of-function approaches. In murine myocardial infarction, infiltration of the infarct border zone with abundant α-SMA-positive myofibroblasts was associated with scar contraction...
November 4, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27818549/giant-nontraumatic-intradiploic-arachnoid-cyst-in-a-young-male
#17
Rajesh Sharma, Puneet Gupta, Manik Mahajan, Poonam Sharma, Anchal Gupta, Arti Khurana
Intradiploic arachnoid cysts have scarcely been reported in the literature, most reported cases being secondary to trauma. Nontraumatic arachnoid cysts are quite rare and have been reported mostly in adults. Here, we report the case of a 16-year-old male presenting with a slowly growing mass in the occipital region and intermittent headaches. On the basis of the findings of X-rays, computed tomography scans, and magnetic resonance imaging scans of the head, the mass was diagnosed as a giant intradiploic arachnoid cyst...
September 2016: Radiologia Brasileira
https://www.readbyqxmd.com/read/27811053/emerging-concepts-and-future-challenges-in-innate-lymphoid-cell-biology
#18
REVIEW
Elia D Tait Wojno, David Artis
Innate lymphoid cells (ILCs) are innate immune cells that are ubiquitously distributed in lymphoid and nonlymphoid tissues and enriched at mucosal and barrier surfaces. Three major ILC subsets are recognized in mice and humans. Each of these subsets interacts with innate and adaptive immune cells and integrates cues from the epithelium, the microbiota, and pathogens to regulate inflammation, immunity, tissue repair, and metabolic homeostasis. Although intense study has elucidated many aspects of ILC development, phenotype, and function, numerous challenges remain in the field of ILC biology...
October 17, 2016: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27809807/nosocomial-infection-of-cchf-among-health-care-workers-in-rajasthan-india
#19
Pragya D Yadav, Deepak Y Patil, Anita M Shete, Prasad Kokate, Pulkit Goyal, Santosh Jadhav, Sanjeev Sinha, Divya Zawar, Surendra K Sharma, Arti Kapil, D K Sharma, Kamlesh J Upadhyay, Devendra T Mourya
BACKGROUND: Ever since Crimean-Congo hemorrhagic fever [CCHF] discovered in India, several outbreaks of this disease have been recorded in Gujarat State, India. During the year 2011 to 2015 several districts of Gujarat and Rajasthan state (Sirohi) found to be affected with CCHF including the positivity among ticks and livestock. During these years many infected individuals succumbed to this disease; which subsequently led to nosocomial infections. Herein, we report CCHF cases recorded from Rajasthan state during January 2015...
November 3, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27808186/cell-biology-phosphate-on-rubbish-out
#20
COMMENT
Arti Tripathi, Susan Gottesman
No abstract text is available yet for this article.
November 2, 2016: Nature
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