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https://www.readbyqxmd.com/read/28937805/laparoscopic-partial-nephrectomy-a-narrative-review-and-comparison-with-open-and-robotic-partial-nephrectomy
#1
Andrew M Ng, Paras H Shah, Louis R Kavoussi
INTRODUCTION: Kidney cancer ranks among the top 10 most prevalent cancers in Western society, ∼90% of which are renal cell carcinomas. There has been a paradigm shift in the management of small renal masses with strong emphasis now placed on nephron-sparing surgery and increased utilization of laparoscopic approaches to partial nephrectomy. In this review, the current state of laparoscopic partial nephrectomy (LPN) is discussed. EVIDENCE ACQUISITION: The PubMed database was queried using the MeSH terms "laparoscopy" and "nephrectomy," as well as the search term "partial...
September 22, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28937383/multicentric-papillary-and-chromophobe-renal-cell-carcinomas-in-a-patient-with-autosomal-dominant-polycystic-kidney-disease-report-of-a-rare-case
#2
Nibedita Sahoo, Susama Patra, Swagatika Senapati, Tushar S Mishra
The causal relationship of autosomal dominant polycystic kidney disease (ADPKD) with the development of renal cell carcinoma (RCC) is still not known. We describe a case of bilateral PKD complicated with a large enhancing mass and multiple small nodules in the left kidney. The histopathological study of the nephrectomy specimen revealed the synchronous occurrence of eosinophilic variant of chromophobe RCC (EVCRCC) and multicentric papillary RCC (PRCC) in a background of ADPKD. To the best of our knowledge, this case is the first to describe the collision tumor of EVCRCC and multicentric PRCC in ADPKD...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28937061/long-term-evaluation-of-kidney-function-in-live-related-kidney-donors
#3
Kalpana S Mehta, Rudramani Swami, Atim Pajai, Sandip Bhurke, Abhishek Shirkande, Sunil Jawle
The consequences of live kidney donation on the donor health with main emphasis on postdonation blood pressure (BP), proteinuria, kidney size, and glomerular filtration rate (GFR) were evaluated. Twenty-five donors with minimum of six months postdonation duration were included in the study. Donor age at nephrectomy, duration postnephrectomy, systolic and diastolic BP measurement pre-and post-donation, postdonation, blood urea nitrogen, serum creatinine and 24-h proteinuria, blood sugar, two-dimensional echocardiogram were recorded...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28934886/occurrence-of-abdominal-bulging-and-hernia-after-open-partial-nephrectomy-a-retrospective-cohort-study
#4
Aapo Inkiläinen, Johan Styrke, Börje Ljungberg, Karin Strigård
OBJECTIVE: Abdominal bulging and incisional hernia are known sequelae after open partial nephrectomy (OPN) via a flank incision. Precise rates are not known. The aims of this study were to determine the rates of bulging and hernia after OPN, and to examine potential risk factors. MATERIALS AND METHODS: A retrospective review was undertaken of 197 consecutive patients operated on with OPN via a flank incision between 2004 and 2014. After exclusion, 184 patients remained...
September 22, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28933511/-renal-pleomorphic-sarcoma-in-four-guinea-pigs-cavia-porcellus
#5
Julia Hankel, Marion Hewicker-Trautwein, Martina Warschau, Anna Milena Thöle, Michael Fehr
OBJECTIVE: Renal tumours apparently are rare not only in cats and dogs, but also in guinea pigs and can be difficult to diagnose. The aim of this study is to describe the clinical, pathological and immunohistochemical findings in guinea pigs with renal tumours. Furthermore, the symptoms, diagnostic possibilities and therapy are compared with renal tumours in other small animals, including cats and dogs. MATERIAL AND METHODS: During a period of 4 years and 4 months the data of guinea pigs that had been presented in the clinic were retrospectively analysed...
September 20, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28933020/deriving-a-management-algorithm-for-emphysematous-pyelonephritis-can-we-rely-on-minimally-invasive-strategies-or-should-we-be-opting-for-earlier-nephrectomy
#6
Eve Boakes, Deepak Batura
PURPOSE: To analyse the incidence and management of emphysematous pyelonephritis (EPN) in North West London and examine factors that influence immediate and 6-month outcomes with the aim of guiding future management. METHODS: This work analyses EPN cases from the London North West Healthcare NHS Trust from October 2006 to July 2015 (population ≈ 850,000). Diagnosis and stage were confirmed by computed tomography (CT). Demographic, clinical, biochemical and microbiological characteristics were assessed...
September 20, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28932690/a-case-of-metastatic-collecting-duct-carcinoma-whose-massive-skull-bone-metastasis-was-prominently-reossified-by-gemcitabine-plus-cisplatin-chemotherapy-combined-with-zoledronic-acid
#7
Makoto Kawaguchi, Keiichi Ito, Hideyuki Shimazaki, Tomohiko Asano
The present case underwent right laparoscopic radical nephrectomy for collecting duct carcinoma (CDC). Recurrence occurred in the lung and the bone (skull and lumber vertebra) in 2011. Gemcitabine plus cisplatin (GC) chemotherapy and monthly zoledronic acid (ZA) was then started. The massive skull bone metastases were prominently reossified after several courses of the therapy. The patient received 16 courses of GC chemotherapy and monthly ZA, and pulmonary metastases and reossified skull bone metastases were stable for 23 months...
November 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28931420/presence-of-periaortic-gas-in-clostridium-septicum-infected-aortic-aneurysm-aids-in-early-diagnosis-a-case-report-and-systematic-review-of-the-literature
#8
Fumihito Ito, Ryota Inokuchi, Akinori Matsumoto, Yoshibumi Kumada, Hideyuki Yokoyama, Tokiya Ishida, Katsuhiko Hashimoto, Masashi Narita, Kazuaki Shinohara
BACKGROUND: Clostridium septicum-infected aortic aneurysm is a fatal and rare disease. We present a fatal case of C. septicum-infected aortic aneurysm and a pertinent literature review with treatment suggestions for reducing mortality rates. CASE PRESENTATION: A 58-year-old Japanese man with an unremarkable medical history presented with a 3-day history of mild weakness in both legs, and experienced paraplegia and paresthesia a day before admission. Upon recognition of signs of an abdominal aortic aneurysm and paraplegia, we suspected an occluded Adamkiewicz artery and performed a contrast-enhanced computed tomography scan, which revealed an aortic aneurysm with periaortic gas extending from his chest to his abdomen and both kidneys...
September 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28929636/risk-factors-for-the-development-of-antibody-mediated-rejection-in-highly-sensitized-pediatric-kidney-transplant-recipients
#9
Irene K Kim, Jua Choi, Ashley Vo, Alexis Kang, Justin Steggerda, Sabrina Louie, Mark Haas, James Mirocha, J Louis Cohen, Helen Pizzo, Elaine S Kamil, Stanley C Jordan, Dechu Puliyanda
ABMR remains a significant concern for early graft loss, especially for those who are HS against HLA antigens. We sought to determine the risk factors leading to ABMR in HS pediatric kidney transplant recipients. From January 2009 to December 2015, 16 HS pediatric kidney transplant patients at our center (age range 2-21) were retrospectively reviewed for outcomes and risk factors for ABMR. All HS patients received desensitization with high-dose IVIG/rituximab prior to transplant. Two groups were examined: ABMR(+) (n = 7) and ABMR(-) (n = 9)...
September 19, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28927783/surgical-resection-of-locally-recurrent-renal-cell-carcinoma-after-nephrectomy-oncological-outcome-and-predictors-of-survival
#10
Roman Herout, Johannes Graff, Angelika Borkowetz, Stefan Zastrow, Steffen Leike, Rainer Koch, Desiree-Louise Draeger, Chris Protzel, Oliver W Hakenberg, Manfred P Wirth, Michael Froehner
OBJECTIVE: To describe the course of disease of patients surgically treated for locally recurrent renal cell carcinoma (LRRCC) after nephrectomy and to identify potential predictive factors for long-term survival. PATIENTS AND METHODS: We, retrospectively, identified 54 patients who underwent surgical resection of LRRCC after open nephrectomy for localized kidney cancer. The median age at time of surgery for LRRCC was 65 years. Survival rates were determined with the Kaplan-Meier method...
September 15, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28927720/neuronal-defects-an-etiological-factor-in-congenital-pelviureteric-junction-obstruction
#11
Guo Yuan How, Kenneth Tou En Chang, Anette Sundfor Jacobsen, Te-Lu Yap, Caroline Choo Phaik Ong, Yee Low, John Carson Allen, Chik Hong Kuick, Malcolm Zhun Leong Lim, Narasimhan Kannan Laksmi
INTRODUCTION: Congenital pelviureteric junction obstruction (PUJO) is one of the most frequent causes of neonatal hydronephrosis. Obstruction at the PUJ has potential severe adverse outcomes, such as renal damage. While pyeloplasty has been established as the definitive treatment, the exact pathophysiology of congenital PUJO remains unknown. Recent research has proposed neuronal innervation defects as an etiological factor in congenital PUJO. We aim to study the expression of various neuronal markers in PUJO specimens compared with controls, and evaluate whether severity of renal disease or dysfunction pre-operatively is related to expression of neuronal markers in resected PUJO specimens...
September 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28926934/the-beneficial-effects-of-allicin-in-chronic-kidney-disease-are-comparable-to-losartan
#12
Ehécatl Miguel Ángel García Trejo, Abraham Said Arellano Buendía, Omegar Sánchez Reyes, Fernando Enrique García Arroyo, Raúl Arguello García, María Lilia Loredo Mendoza, Edilia Tapia, Laura Gabriela Sánchez Lozada, Horacio Osorio Alonso
Recent studies suggest that allicin may play a role in chronic kidney disease (CKD), reducing hypertension and oxidative stress and improving renal dysfunction. In the present study, CKD was induced by 5/6 nephrectomy and the animals were divided into four treatment groups as follows: control (C), CKD, CKD+allicin (40 mg/kg pathway oral) (CKDA), and CKD+Losartan (20 mg/kg) (CKDL). After CKD induction, the rats developed hypertension from week 3 to the end of the study. This was associated with increased creatinine and blood urea nitrogen (BUN) levels in serum, increased albuminuria, increased urinary excretion of N-acetyl-β-d-glucosaminidase (NAG), increased nephrin expression, and incrased histological alterations in the cortex...
September 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28924734/evaluation-of-a-novel-electrosurgical-sealing-mode-in-an-ex-vivo-and-in-vivo-porcine-model
#13
Karolin Thiel, Walter Linzenbold, Markus D Enderle, B Nold, Alfred Königsrainer, Martin Schenk, Christian Thiel
BACKGROUND: Bipolar vessel sealing has been successfully introduced in a variety of procedures like prostatectomy, hysterectomy, and nephrectomy. In this study, we evaluated a new sealing mode-the thermoSEAL(®) mode (TSM)-operated with the VIO3 generator in an ex vivo and in vivo animal study and compared the results with the commercially available BiClamp mode (BCM), operated with the VIO300D generator. Two different instruments were used in combination with both modes, BiCision(®) and BiClamp(®) 201T (Erbe Elektromedizin GmbH)...
September 18, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28924138/perioperative-ketorolac-use-a-potential-risk-factor-for-renal-dysfunction-after-live-donor-nephrectomy
#14
Kazuhiro Takahashi, Anita K Patel, Shunji Nagai, Mohamed Safwan, Krishna G Putchakayala, William J Kane, Lauren E Malinzak, Jason E Denny, Atsushi Yoshida, Dean Y Kim
BACKGROUND Ketorolac is a nonsteroidal anti-inflammatory drug indicated for pain control after surgeries in many fields. The aim of this study was to evaluate the impact of ketorolac use after live-donor nephrectomy (LDN). MATERIAL AND METHODS We reviewed data on 251 patients who underwent laparoscopic LDN from April 2008 to March 2016. Ketorolac was given to 167 patients intraoperatively or postoperatively within 24 h after LDN. Glomerular filtration rate (GFR) percentage was defined as postoperative GFR/preoperative GFR...
September 19, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28924109/retroperitoneal-bulky-histiocytic-sarcoma-successfully-treated-with-induction-chemotherapy-followed-by-curative-surgery
#15
Masafumi Oto, Akiko Maeda, Taku Nose, Yujiro Ueda, Shima Uneda, Akito Inadome, Koichi Oshima, Minoru Yoshida
Histiocytic sarcoma (HS) is a rare hematopoietic neoplasm. We report a patient with HS treated with induction chemotherapy followed by curative surgery. A 50-year-old man was referred to our hospital because of a retroperitoneal tumor. A computed tomography scan revealed a bulky retroperitoneal mass, infiltrating the surrounding organ. An excisional biopsy confirmed the diagnosis of HS. The tumor shrunk after multidrug chemotherapy. However, positron emission tomography showed uptake of fludeoxyglucose in the residual tumor...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28923617/postdonation-anemia-in-living-kidney-donors
#16
S Shah, B Lankowsky, T Gao, Z Zaky, B R Stephany, E D Poggio
BACKGROUND: The effect of nephrectomy on development of anemia in living kidney donation has not been well studied. We hypothesized that the remaining kidney volume and function after donation are determinants of hemoglobin (Hb) concentration and postdonation anemia (PDA). METHODS: We studied 398 living kidney donors (LKDs) who donated from January 2001 to December 2013. Demographic variables, hematologic variables, renal mass, and renal function were investigated as factors associated with PDA with the use of univariate and multivariable logistical regression analysis...
October 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28922687/comparison-of-perioperative-renal-and-oncologic-outcomes-in-robotic-assisted-versus-open-partial-nephrectomy
#17
Jo-Lynn Tan, Mark Frydenberg, Jeremy Grummet, Uri Hanegbi, Ross Snow, Sarah Mann, Kirobel Begashaw, Daniel Moon
BACKGROUND: To compare perioperative, renal and oncological outcomes after robotic-assisted partial nephrectomy (RAPN) versus open partial nephrectomy (OPN) for the treatment of renal tumours. METHODS: All partial nephrectomies performed at a Metropolitan Urology Centre between 2010 and 2016 were analysed. Baseline data was collected for patient demographics, tumour characteristics (tumour size, laterality and polarity, RENAL scores), and perioperative variables (e...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28920823/diagnosis-and-treatment-of-a-unilateral-renal-cystadenoma-in-an-african-lion-panthera-leo
#18
Ronan Eustace, Jacob Rubin, Kimberly A Thompson, Kyle Snowdon, James G Sikarskie, Colleen Monahan, Rebecca C Smedley
A renal tubular cystadenoma was diagnosed in a 14-yr-old male African lion (Panthera leo). During a routine health evaluation, a left renal mass was identified via physical examination, radiographs, and abdominal ultrasonography. The mass was 30 × 15 cm in size and had a thin capsule with central hypoechoic fluid, suggestive of a perirenal cyst. An exploratory celiotomy with partial nephrectomy was performed without complications. Histologically, the tumor was characterized by a thick fibrous capsule surrounding multiple, variable-sized cysts that markedly compressed the adjacent fibrotic and atrophied renal cortex...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28918405/renal-cell-carcinoma-with-isolated-metastasis-to-sigmoid-mesentery-a-rare-resectable-combination
#19
Hira Lal, Priyank Yadav, Shashidhar Achar, Uday Pratap Singh
Renal cell carcinoma accounts for 2%-3% of all malignancies in adults. It spreads via direct extension, lymphatic route as well as haematogenous route. Lymph nodes, lungs, bone, liver and brain are the usual sites for its metastatic spread. In the presence of limited metastatic disease with potentially resectable metastases, surgery offers the best chances of cure. In the present case, we describe a case of renal cell carcinoma with a solitary metastasis to the sigmoid mesentery in a patient with Von Hippel-Lindau syndrome...
September 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28918166/high-expression-of-cxc-chemokine-receptor-6-associates-with-poor-prognosis-in-patients-with-clear-cell-renal-cell-carcinoma
#20
Yuan Chang, Lin Zhou, Le Xu, Qiang Fu, Yuanfeng Yang, Zongming Lin, Jiejie Xu
PURPOSE: Accumulating evidence indicates that CXC chemokine receptor 6 (CXCR6) has a crucial role in cancer development and progression, however, its role in clear cell renal cell carcinoma (ccRCC) remains obscure. The aim of this study is to investigate the prognostic value of CXCR6 expression in patients with ccRCC following surgery. MATERIALS AND METHODS: This study retrospectively included 239 patients with ccRCC who underwent nephrectomy and had paraffin tissue available at a single center...
September 13, 2017: Urologic Oncology
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