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https://www.readbyqxmd.com/read/29220439/text-mining-and-expert-curation-to-develop-a-database-on-psychiatric-diseases-and-their-genes
#1
Alba Gutiérrez-Sacristán, Àlex Bravo, Marta Portero-Tresserra, Olga Valverde, Antonio Armario, M C Blanco-Gandía, Adriana Farré, Lierni Fernández-Ibarrondo, Francina Fonseca, Jesús Giraldo, Angela Leis, Anna Mané, M A Mayer, Sandra Montagud-Romero, Roser Nadal, Jordi Ortiz, Francisco Javier Pavon, Ezequiel Jesús Perez, Marta Rodríguez-Arias, Antonia Serrano, Marta Torrens, Vincent Warnault, Ferran Sanz, Laura I Furlong
Database URL: http://www.psygenet.org. PsyGeNET corpus: http://www.psygenet.org/ds/PsyGeNET/results/psygenetCorpus.tar.
January 1, 2017: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/29206894/liver-transplantation-in-patients-with-alcoholic-liver-disease-a-retrospective-study
#2
Gabriele A Vassallo, Claudia Tarli, Maria M Rando, Carolina Mosoni, Antonio Mirijello, Adwoa Agyei-Nkansah, Mariangela Antonelli, Luisa Sestito, Germano Perotti, Daniela Di Giuda, Salvatore Agnes, Antonio Grieco, Antonio Gasbarrini, Giovanni Addolorato
Aim: Alcoholic liver disease (ALD) is the most common liver disease in the Western World. Liver transplantation (LT) is the treatment for end-stage ALD. However, many transplant centers are still reluctant to transplant these patients because of the risk of alcohol relapse, recurrence of the primary liver disease and associated post-transplant complications. We examined survival rate, prevalence of primary liver disease recurrence, re-transplantation and post-transplant complications among transplanted patients for alcoholic cirrhosis compared with those transplanted for viral cirrhosis...
December 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29196480/is-the-admission-test-for-a-course-in-medicine-a-good-predictor-of-academic-performance-a-case-control-experience-at-the-school-of-medicine-of-turin
#3
Giuseppe Migliaretti, Salvatore Bozzaro, Roberta Siliquini, Ilaria Stura, Giuseppe Costa, Franco Cavallo
OBJECTIVES: The usefulness of university admission tests to medical schools has been discussed in recent years. In the academic year 2014-15 in Italy, several students who failed the admission test appealed to the regional administrative court ('Tribunale Amministrativo Regionale'-TAR) requesting to be included, despite their test results, and all were admitted to their respective courses. The existence of this population of students generated a control group, in order to evaluate the predictive capacity of the admission test...
December 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/29187790/seahorses-of-the-hippocampus-coronatus-complex-taxonomic-revision-and-description-of-hippocampus-haema-a-new-species-from-korea-and-japan-teleostei-syngnathidae
#4
Sang-Yun Han, Jin-Koo Kim, Yoshiaki Kai, Hiroshi Senou
Morphological and molecular analyses were conducted on 182 specimens belonging to the Hippocampus coronatus complex (H. coronatus sensu lato), collected in Korea and Japan 1933-2015, in order to clarify the taxonomic status of the species within this complex. Three species are recognized based on the shape of the coronet, the number of trunk rings (TrR) and tail rings (TaR), and presence or absence of a wing-tip spine (WS) at the dorsal fin base. Hippocampus coronatus Temminck & Schlegel, 1850 (H. coronatus sensu stricto), is diagnosed by 10 TrR, 37-40 TaR, an extremely high coronet (55...
2017: ZooKeys
https://www.readbyqxmd.com/read/29187283/new-insights-into-transglutaminase-2-and-links-to-neurodegenerative-diseases
#5
Boram Min, Kwang Chul Chung
Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (NDDs), which include amyotrophic lateral sclerosis (ALS), Alzheimer's, Parkinson's, Huntington's, and prion diseases. The transglutaminase 2 (TG2) gene encodes a multifunctional enzyme, displaying four types of activity, such as transamidation, GTPase, protein disulfide isomerase, and protein kinase activities. Many studies demonstrated that the calcium-dependent transamidation activity of TG2 affected the formation of insoluble and toxic amyloid aggregates that mainly consisted of NDD-related proteins...
November 29, 2017: BMB Reports
https://www.readbyqxmd.com/read/29186357/outcome-of-ankle-arthrodesis-and-ankle-prosthesis-a-review-of-the-current-status
#6
Nicola Maffulli, Umile Giuseppe Longo, Joel Locher, Giovanni Romeo, Giuseppe Salvatore, Vincenzo Denaro
Introduction: In advanced stages of ankle osteoarthritis (OA), ankle arthrodesis (AA) or total ankle arthroplasty (TAR) may be necessary. Our purpose is to compare AA and total ankle replacement for the surgical management of end stage ankle OA. Sources of data: We conducted a literature search of PubMed, Medline, CINAHL, Cochrane, Embase and Google Scholar databases using the terms 'ankle' in combination with 'OA', 'arthrodesis', 'arthroplasty', 'joint fusion', 'joint replacement'...
November 23, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/29181969/a-dnazyme-based-nanomachine-for-in-situ-detection-of-microrna-in-living-cells
#7
Jing Liu, Meirong Cui, Hong Zhou, Wenrong Yang
The capability of in situ detection of microRNA in living cells with signal amplification strategy is of fundamental im-portance, and it will open up a new opportunity in development of diagnosis and prognosis of many diseases. Herein we report a swing DNA nanomachine for intracellular microRNA detection. The surfaces of Au nanoparticles (NPs) are modi-fied by two hairpin DNA. We observe that one DNA (MB2) will open its hairpin structure upon partly hybridization with tar-get miR-21 after entering into cells, and the other part of its hairpin structure could further react with the other hairpin DNA (MB1) to form Zn2+ -specific DNAzyme, and then resulted MB1 disrupted from the middle through shearing action and the release of fluorescein Cy5...
November 28, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29180993/co-carcinogenesis-human-papillomaviruses-coal-tar-derivatives-and-squamous-cell-cervical-cancer
#8
Harry W Haverkos, Gregory P Haverkos, Michael O'Mara
Cervical cancer (CC) is the fourth most common cancers among women worldwide. Human papillomaviruses (HPVs) play a major role in the etiology of CC, with several lines of epidemiologic and experimental evidence supporting a role for non-viral (co-carcinogens) and host genetic factors in controlling the risk for progression to neoplasia among HPV-infected individuals. The role of co-carcinogens in the development of CC is significant in the developing world where poor sanitation and other socio-economic conditions increase the infectious cancer burden...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29178004/pcdd-pcdf-formation-in-the-chlor-alkali-process-laboratory-study-and-comparison-with-patterns-from-contaminated-sites
#9
Teru Yamamoto, Kazuo Higashino, Tamae Abe, Takumi Takasuga, Hiroaki Takemori, Roland Weber, Yuko Sasaki
Studies on the formation of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) during the electrolysis of sodium chloride solution (brine) using graphite or titanium electrodes were carried out at a laboratory scale. High concentrations of PCDFs but no PCDDs were formed in tests using graphite electrodes. With titanium electrodes, PCDFs were only formed when tar pitch was added and mainly originated from the dibenzofuran present in the tar. For the first time, a detailed assessment of the formation of mono- to octachlorinated PCDD/PCDF from tar pitch was investigated...
November 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29171790/transcriptomic-analysis-of-arabidopsis-seedlings-in-response-to-agrobacterium-mediated-transformation-process
#10
Kaixuan Duan, Christopher Willig, Joann R de Tar, William G Spollen, Zhanyuan Zhang
Agrobacterium tumefaciens is a plant pathogen that causes crown-gall disease. This pathogen is capable of transferring the T-DNA from its Ti-plasmid to the host cell then integrating it into the host genome. To date, this genetic transformation ability has been harnessed as a dominant technology to produce genetically modified plants for both basic research and crop biotechnological applications. However, little is known about the interaction between Agrobacterium and host plants, especially the host responses to Agrobacterium infection and its associated factors...
November 24, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/29169820/robotic-and-hybrid-robotic-transversus-abdominis-release-may-be-performed-with-low-length-of-stay-and-wound-morbidity
#11
Joshua T Halka, Andrew Vasyluk, Alexander M DeMare, Randy J Janczyk, Anthony A Iacco
The objective of our study was to compare length of stay and wound complications after hybrid robotic transversus abdominis release (hrTAR) vs. robotic transversus abdominis release (rTAR) Two cohorts of patients undergoing robotic (rTAR) and hybrid robotic (hrTAR) performed by two surgeons at a single institution were analyzed. Mean length of stay (LOS) and incidence of surgical site occurrences (SSO) were compared. 57 patients undergoing rTAR and 25 patients undergoing hrTAR were analyzed. The hrTAR group had larger mean hernia dimensions and a larger proportion of men but otherwise the patient cohorts were similar...
November 13, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29167254/draft-genome-sequence-of-the-arsenic-resistant-bacterium-brevundimonas-denitrificans-tar-002-t
#12
Taishi Tsubouchi, Yukihiro Kaneko
We report the 3.2-Mb draft genome sequence of Brevundimonas denitrificans strain TAR-002(T), isolated from deep-sea floor sediment. The draft genome sequence of strain TAR-002(T) consists of 3,231,216 bp in 44 contigs, with a G+C content of 68.47%, 3,866 potential coding sequences (CDSs), 3 rRNAs, and 45 tRNAs.
November 22, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29163144/the-relationship-of-cognitive-performance-and-the-theta-alpha-power-ratio-is-age-dependent-an-eeg-study-of-short-term-memory-and-reasoning-during-task-and-resting-state-in-healthy-young-and-old-adults
#13
Janet P Trammell, Priscilla G MacRae, Greta Davis, Dylan Bergstedt, Ariana E Anderson
Objective: The Theta-Alpha ratio (TAR) is known to differ based upon age and cognitive ability, with pathological electroencephalography (EEG) patterns routinely found within neurodegenerative disorders of older adults. We hypothesized that cognitive ability would predict EEG metrics differently within healthy young and old adults, and that healthy old adults not showing age-expected EEG activity may be more likely to demonstrate cognitive deficits relative to old adults showing these expected changes. Methods: In 216 EEG blocks collected in 16 young and 20 old adults during rest (eyes open, eyes closed) and cognitive tasks (short-term memory [STM]; matrix reasoning [RM; Raven's matrices]), models assessed the contributing roles of cognitive ability, age, and task in predicting the TAR...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29158705/melatonin-attenuates-thiocyanate-induced-vasoconstriction-in-aortic-rings
#14
Alexander M Prusa, Christian A Plass
Cigarette smoking not only has a carcinogenic effect but also leads to an increase in arterial blood pressure. Besides its main components, i.e. nicotine, tar, and carbon monoxide, cigarette smoke also contains thiocyanate. Thiocyanate anions (SCN(-)) arise from the detoxification of hydrogen cyanide and its plasma concentrations were found to correlate significantly with cigarette consumption. There is also evidence that atherosclerotic disease progression is much more rapid when serum SCN(-) levels are increased...
November 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29158002/sofc-single-cells-fed-by-biogas-experimental-tests-with-trace-contaminants
#15
Davide Papurello, Andrea Lanzini
Biogas from biological treatments and from the waste degradation in landfills generally contains a wide range of trace impurities (e.g., sulphur compounds, siloxanes, halogens, tar compounds, etc.). This paper describes an experimental analysis performed with SOFC single cells fed by a synthetic gas polluted by H2S, HCl, D4 and a mixture of H2S + C2Cl4. The aim is to detect the threshold tolerance limit on different cell performance parameters. Results show how: hydrogen sulphide has a strong impact on the polarization losses due to the nickel sulphide formation on the electrode that causes a mass transfer resistance...
November 17, 2017: Waste Management
https://www.readbyqxmd.com/read/29156170/computed-navigation-guidance-for-ankle-replacement-in-the-setting-of-ankle-deformity
#16
REVIEW
Feras J Waly, Nicholas E Yeo, Murray J Penner
Total ankle replacement (TAR) has evolved over the past decade as a treatment for end-stage ankle arthritis with improved survivorship. Despite the improving outcomes, ankle deformity represents a challenge to the foot and ankle surgeon with increased risk of implant failure. The use of preoperative computer-assisted guidance has led to better understanding the 3-dimensional ankle anatomy and associated deformities and allows for reproducible, anatomic placement of the TAR components.
January 2018: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/29153904/comparison-of-cellulose-vs-plastic-cigarette-filter-decomposition-under-distinct-disposal-environments
#17
François-Xavier Joly, Mathieu Coulis
It is estimated that 4.5 trillion cigarette butts are discarded annually, making them numerically the most common type of litter on Earth. To accelerate their disappearance after disposal, a new type of cigarette filters made of cellulose, a readily biodegradable compound, has been introduced in the market. Yet, the advantage of these cellulose filters over the conventional plastic ones (cellulose acetate) for decomposition, remains unknown. Here, we compared the decomposition of cellulose and plastic cigarettes filters, either intact or smoked, on the soil surface or within a composting bin over a six-month field decomposition experiment...
November 15, 2017: Waste Management
https://www.readbyqxmd.com/read/29149889/electronic-cigarette-vapor-alters-the-lateral-structure-but-not-tensiometric-properties-of-calf-lung-surfactant
#18
Rebecca J Przybyla, Jason Wright, Rajan Parthiban, Saeed Nazemidashtarjandi, Savas Kaya, Amir M Farnoud
BACKGROUND: Despite their growing popularity, the potential respiratory toxicity of electronic cigarettes (e-cigarettes) remains largely unknown. One potential aspect of e-cigarette toxicity is the effect of e-cigarette vapor on lung surfactant function. Lung surfactant is a mixture of lipids and proteins that lines the alveolar region. The surfactant layer reduces the surface tension of the alveolar fluid, thereby playing a crucial role in lung stability. Due to their small size, particulates in e-cigarette vapor can penetrate the deep lungs and come into contact with the lung surfactant...
November 17, 2017: Respiratory Research
https://www.readbyqxmd.com/read/29149750/friends-or-foes-monetized-life-cycle-assessment-and-cost-benefit-analysis-of-the-site-remediation-of-a-former-gas-plant
#19
Lies Huysegoms, Sandra Rousseau, Valérie Cappuyns
Site contamination is a global concern because of the potential risks for human health and ecosystem quality. Every contaminated site has its own specific characteristics and the increased availability and efficiency of remediation techniques makes the choice of remediation alternative increasingly complicated. In this paper an attributional Life Cycle Assessment (LCA) of the secondary environmental impacts of a site remediation is performed and its results are monetized using two different monetization techniques, namely Stepwise 2006 and Ecovalue 08...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29148719/effect-of-antigen-retrieval-methods-on-non-specific-binding-of-anti-body-metal-nanoparticle-conjugates-on-ffpe-tissue
#20
Yuying Zhang, Xinping Wang, Sven Perner, Ágnes Bánkfalvi, Sebastian Schlücker
Immunohistochemical analysis of FFPE tissues provides important diagnostic and prognostic information in pathology. Metal nanoparticles (NPs) and in particular surface-enhanced Raman scattering (SERS) nanotags as a new class of labelling reagents are promising to be used for multiplexed protein profiling on tissue sections. However, non-specific binding of NPs onto the tissue specimens greatly hampers their clinical applications. In this study, we found that the antigen retrieval method strongly influences the extent of non-specific binding of the antibody-SERS NP conjugates to the tissue...
November 17, 2017: Analytical Chemistry
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