Nidan Qiao, Wei Gao, Xingli Deng, Tao Xin, Gangli Zhang, Nan Wu, Pan Wang, Yunke Bi, Zixiang Cong, Zhiyi Zhou, Junjun Li, Shengyu Sun, Meng Li, Wenlong Tang, Xiaorong Yan, Wenxiong Wang, Wenjin Chou, Shun Yao, Zhao Ye, Zengyi Ma, Xiang Zhou, Xiaoyun Cao, Ming Shen, Xuefei Shou, Zhaoyun Zhang, Zhenyu Wu, Liangzhao Chu, Yongming Qiu, Hui Ma, Anhua Wu, Chiyuan Ma, Meiqing Lou, Changzhen Jiang, Yongfei Wang, Yao Zhao
BACKGROUND: Surgical treatment of complex giant pituitary adenomas (GPAs) presents significant challenges. The efficacy and safety of combining transsphenoidal and transcranial approaches for these tumors remain controversial. In this largest cohort of patients with complex GPAs, we compared the surgical outcomes between those undergoing a combined regimen and a non-combined regimen. We also examined the differences in risks of complications, costs, and logistics between the two groups, which might offer valuable information for the appropriate management of these patients...
March 18, 2024: International Journal of Surgery