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https://www.readbyqxmd.com/read/28317271/baclofen-and-alcohol-dependent-patients-a-real-risk-of-severe-self-poisoning
#1
David Boels, Caroline Victorri-Vigneau, Marie Grall-Bronnec, Ali Touré, Anais Garnier, Alain Turcant, Gaël Le Roux
Baclofen is often prescribed in high doses to fight cravings experienced by alcohol-dependent patients. Such an increase in the availability of baclofen is concerning. This study aimed to determine the change in number and profile of self-poisoning with baclofen over time, since baclofen has become increasingly popular, in order to describe the severity of self-poisoning with baclofen and to focus on co-existing alcohol use disorders and psychiatric illnesses determine predictors of severity. This was a retrospective study of self-poisoning with baclofen as reported by the western France Poison Control Center (PCC), which represents a population of more than 12 million people from January 2008 to March 2014...
March 19, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28314060/-these-power-lines-make-me-ill-a-typology-of-residents-health-responses-to-a-new-high-voltage-power-line
#2
Jarry T Porsius, Liesbeth Claassen, Fred Woudenberg, Tjabe Smid, Danielle R M Timmermans
Little attention has been devoted to the potential diversity in residents' health responses when exposed to an uncertain environmental health risk. The present study explores whether subgroups of residents respond differently to a new high-voltage power line (HVPL) being put into operation. We used a quasi-experimental prospective field study design with two pretests during the construction of a new HVPL, and two posttests after it was put into operation. Residents living nearby (0-300 m, n = 229) filled out questionnaires about their health and their perception of the environment...
March 17, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28299540/psychosocial-needs-of-patient-s-relatives-and-health-care-providers-in-a-pediatric-critical-care-unit
#3
Sasidaran Kandasamy, Niranjan Vijayakumar, Rupesh Kumar Natarajan, Thangavelu Sangaralingam, Nedunchelian Krishnamoorthi
OBJECTIVE: To describe the needs of relatives of children admitted to an Intensive Care Unit and compare their needs with the perspectives of doctors, nurses and administrators. METHODS: This is a descriptive comparative study done at a tertiary care PICU from South India. A modified Critical Care Family Needs Inventory (CCFNI) (internal consistency reliability =0.93) was used to assess the needs of 35 family members, 30 nurses, 30 doctors and 30 administrators...
March 16, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28293145/nursing-home-nurses-and-community-dwelling-older-adults-reported-knowledge-attitudes-and-behavior-toward-antibiotic-use
#4
Christine E Kistler, Anna Beeber, Sylvia Becker-Dreps, Kimberly Ward, Megan Meade, Brittany Ross, Philip D Sloane
BACKGROUND: Antibiotic overuse causes antibiotic resistance, one of the most important threats to human health. Older adults, particularly those in nursing homes, often receive antibiotics when they are not indicated. METHODS: To understand knowledge, attitudes, and behaviors of nursing home (NH) nurses and community-dwelling older adults towards antibiotic use, especially in clinical situations consistent with antibiotic overuse, we conducted a mixed-method survey in two NHs and one Family Medicine clinic in North Carolina, among English-speaking nurses and community-dwelling, cognitively intact adults aged 65 years or older...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28290932/primary-care-of-men-who-have-sex-with-men-in-the-u-s-military-in-the-post-don-t-ask-don-t-tell-era-a-review-of-recent-progress-health-needs-and-challenges
#5
Wesley R Campbell, Mojgan Jahan, Mary F Bavaro, Robert J Carpenter
BACKGROUND: With repeal of "Don't Ask, Don't Tell" (DADT) in 2011 and the Supreme Court decision regarding Section 3 of the Defense of Marriage Act (DOMA) in 2013, military providers are now able to openly address unique health needs of lesbian, gay, and bisexual (LGB) service members and their same-sex spouse beneficiaries. These federal laws created health care barriers, either real or perceived, between providers and patients and often limited medical research involving LGB patients in the Military Health System (MHS)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28286544/acute-appendicitis-inflammatory-appendiceal-mass-and-the-risk-of-a-hidden-malignant-tumor-a-systematic-review-of-the-literature
#6
REVIEW
Frederico José Ribeiro Teixeira, Sérgio Dias do Couto Netto, Eduardo Hiroshi Akaishi, Edivaldo Massazo Utiyama, Carlos Augusto Metidieri Menegozzo, Marcelo Cristiano Rocha
INTRODUCTION: Acute appendicitis is significantly common. Despite the increased use of computed tomography, the number of perforated cases has been stable in the past three decades. Between 2% and 6% of patients with acute appendicitis present appendiceal mass, often described as inflammatory phlegmon or abscess. Malignant tumors are confirmed by pathological analysis in 0.9-1.4% of all appendectomies performed to treat acute appendicitis. However, recent series demonstrate an elevated incidence of malignancies, ranging from 5...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28282303/diversity-in-the-emerging-critical-care-workforce-analysis-of-demographic-trends-in-critical-care-fellows-from-2004-to-2014
#7
Meghan B Lane-Fall, Todd A Miano, Jaya Aysola, John G T Augoustides
OBJECTIVES: Diversity in the physician workforce is essential to providing culturally effective care. In critical care, despite the high stakes and frequency with which cultural concerns arise, it is unknown whether physician diversity reflects that of critically ill patients. We sought to characterize demographic trends in critical care fellows, who represent the emerging intensivist workforce. DESIGN: We used published data to create logistic regression models comparing annual trends in the representation of women and racial/ethnic groups across critical care fellowship types...
March 9, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28276806/psychobiological-impact-of-ethnic-discrimination-in-turkish-immigrants-living-in-germany
#8
Susanne Fischer, Urs M Nater, Jana Strahler, Nadine Skoluda, Leander Dieterich, Orgun Oezcan, Ricarda Mewes
Perceived ethnic discrimination has a negative impact on health. One of the key mechanisms may be a dysregulation of stress-responsive systems. Our aims were to investigate whether (1) acute face-to-face ethnic discrimination induces a stress response, and (2) to compare long-term endocrine functioning between immigrants and nonimmigrants. 30 male Turkish immigrants living in Germany underwent an ethnic discrimination condition and a control condition in the laboratory. Perceived ethnic discrimination, stress, salivary alpha-amylase and cortisol were measured four times...
March 5, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28275923/conceptualizing-culturally-infused-engagement-and-its-measurement-for-ethnic-minority-and-immigrant-children-and-families
#9
REVIEW
Miwa Yasui, Kathleen J Pottick, Yun Chen
Despite the central role culture plays in racial and ethnic disparities in mental health among ethnic minority and immigrant children and families, existing measures of engagement in mental health services have failed to integrate culturally specific factors that shape these families' engagement with mental health services. To illustrate this gap, the authors systematically review 119 existing instruments that measure the multi-dimensional and developmental process of engagement for ethnic minority and immigrant children and families...
March 8, 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28270381/self-reported-psychosomatic-complaints-in-swedish-children-adolescents-and-young-adults-living-in-rural-and-urban-areas-an-internet-based-survey
#10
Katarina Laundy Frisenstam, Matilda van den Bosch, Yun Chen, Peter Friberg, Walter Osika
BACKGROUND: Frequencies in reported psychosomatic illnesses have increased in Sweden among children, adolescents, and young adults. Little is known about demographic differences in self-reported psychosomatic complaints, such as between urban and rural areas, and whether surveys launched on the Internet could be a useful method in sampling such data. OBJECTIVES: This study examines the connection between psychosomatic illnesses and demographics in Swedish children and youth...
March 7, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28263891/skin-contamination-as-pathway-for-nicotine-intoxication-in-vapers
#11
Giovanni Maina, Carlotta Castagnoli, Giordana Ghione, Valter Passini, Gianpiero Adami, Francesca Larese Filon, Matteo Crosera
Growing warnings on health effects related to electronic cigarettes have met inconclusive findings at present. This study analyzed the in vitro percutaneous absorption of nicotine resulting by skin contamination with two e-liquids (refill 1 and 2) containing nicotine at 1.8%. Donor chambers of 6 Franz cells for each refill liquid were filled with 1mL of nicotine e-liquid for 24h; at selected intervals, 1.5mL of the receptor solutions were collected for nicotine concentration analysis by mean gas chromatography-mass spectrometry (LOD: 0...
March 2, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28261068/gabrb1-single-nucleotide-polymorphism-associated-with-altered-brain-responses-but-not-performance-during-measures-of-impulsivity-and-reward-sensitivity-in-human-adolescents
#12
Theodora Duka, Kyriaki Nikolaou, Sarah L King, Tobias Banaschewski, Arun L W Bokde, Christian Büchel, Fabiana M Carvalho, Patricia J Conrod, Herta Flor, Jürgen Gallinat, Hugh Garavan, Andreas Heinz, Tianye Jia, Penny Gowland, Jean-Luc Martinot, Tomáš Paus, Marcella Rietschel, Trevor W Robbins, Michael Smolka, Gunter Schumann, David N Stephens
Variations in genes encoding several GABAA receptors have been associated with human drug and alcohol abuse. Among these, a number of human studies have suggested an association between GABRB1, the gene encoding GABAA receptor β1 subunits, with Alcohol dependence (AD), both on its own and comorbid with other substance dependence and psychiatric illnesses. In the present study, we hypothesized that the GABRB1 genetically-associated increased risk for developing alcoholism may be associated with impaired behavioral control and altered sensitivity to reward, as a consequence of altered brain function...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28254729/correlation-study-on-chromogranin-a-genetic-polymorphism-and-prognosis-of-critically-ill-patients
#13
Jing-Lun Liu, Xiao-Ying Chen, Ni-Na Gu, Jin-Ye Zhang, Li-Ping Jiang, Dan Zhang, Guo-Sheng Ren
OBJECTIVE: The objective was to investigate the correlation between single nucleotide polymorphism (SNP) of chromogranin A (CHGA) and prognosis of critically ill patients. METHODS: We screened 357 critically ill patients consecutively admitted to our intensive care unit. The -89/-415/-462 SNP locus in the promoter region and the +9559/+9578/+9590/+9611 SNP locus in exon 7 coding of CHGA were genotyped by polymerase chain reaction and DNA sequencing technology. Subsequently, the correlation between genotype and prognosis of patients was analyzed...
February 13, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28241780/thromboelastometry-versus-standard-coagulation-tests-versus-restrictive-protocol-to-guide-blood-transfusion-prior-to-central-venous-catheterization-in-cirrhosis-study-protocol-for-a-randomized-controlled-trial
#14
Leonardo Lima Rocha, Camila Menezes Souza Pessoa, Ary Serpa Neto, Rogerio Ruscitto do Prado, Eliezer Silva, Marcio Dias de Almeida, Thiago Domingos Correa
BACKGROUND: Liver failure patients have traditionally been empirically transfused prior to invasive procedures. Blood transfusion is associated with immunologic and nonimmunologic reactions, increased risk of adverse outcomes and high costs. Scientific evidence supporting empirical transfusion is lacking, and the best approach for blood transfusion prior to invasive procedures in cirrhotic patients has not been established so far. The aim of this study is to compare three transfusion strategies (routine coagulation test-guided - ordinary or restrictive, or thromboelastometry-guided) prior to central venous catheterization in critically ill patients with cirrhosis...
February 27, 2017: Trials
https://www.readbyqxmd.com/read/28239018/rural-african-americans-perspectives-on-mental-health-comparing-focus-groups-and-deliberative-democracy-forums
#15
Greer Sullivan, Ann Cheney, Mary Olson, Tiffany Haynes, Keneshia Bryant, Naomi Cottoms, Christina Reaves, Geoff Curran
A number of approaches have been used to obtain community members' health perspectives. Health services researchers often conduct focus groups while political scientists and community groups may hold forums. To compare and contrast these two approaches, we conducted six focus groups (n = 50) and seven deliberative democracy forums (n = 233) to obtain the perspectives of rural African Americans on mental health problems in their community. Inductive qualitative analysis found three common themes: rural African Americans (1) understood stresses of poverty and racism were directly related to mental health, (2) were concerned about widespread mental illness stigma, and (3) thought community members could not identify mental health problems requiring treatment...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28230530/developing-a-multi-component-immune-model-for-evaluating-the-risk-of-respiratory-illness-in-athletes
#16
Maree Gleeson, David B Pyne, Lisa J Elkington, Sharron T Hall, John R Attia, Christopher Oldmeadow, Lisa G Wood, Robin Callister
Clinical and laboratory identification of the underlying risk of respiratory illness in athletes has proved problematic. The aim of this study was to determine whether clinical data, combined with immune responses to standardised exercise protocols and genetic cytokine polymorphism status, could identify the risk of respiratory illness (symptoms) in a cohort of highly-trained athletes. Male endurance athletes (n=16; VO2max 66.5 ± 5.1 mL.kg-1.min-1) underwent a clinical evaluation of known risk factors by a physician and comprehensive laboratory analysis of immune responses both at rest and after two cycling ergometer tests: 60 min at 65% VO2max (LONG); and 6 x 3 min intervals at 90% VO2max (INTENSE)...
2017: Exercise Immunology Review
https://www.readbyqxmd.com/read/28228178/the-state-of-emergency-medical-services-ems-systems-in-africa
#17
Nee-Kofi Mould-Millman, Julia M Dixon, Nana Sefa, Arthur Yancey, Bonaventure G Hollong, Mohamed Hagahmed, Adit A Ginde, Lee A Wallis
Introduction Little is known about the existence, distribution, and characteristics of Emergency Medical Services (EMS) systems in Africa, or the corresponding epidemiology of prehospital illness and injury. METHODS: A survey was conducted between 2013 and 2014 by distributing a detailed EMS system questionnaire to experts in paper and electronic versions. The questionnaire ascertained EMS systems' jurisdiction, operations, finance, clinical care, resources, and regulatory environment...
February 23, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28214723/how-financial-strain-affects-health-evidence-from-the-dutch-national-bank-household-survey
#18
Carla Prentice, Donal McKillop, Declan French
The mechanisms by which financial strain affects health are not well understood. In this paper, we conduct a longitudinal mediation analysis of the Dutch National Bank Household Survey. To quantify the relative importance of biological and nonbiological pathways from financial strain to health, we consider smoking, heavy drinking and being overweight as plausible behavioural responses to financial strain but find that only 4.9% of the response of self-reported health to financial strain is mediated by these behaviours...
February 14, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28212250/economic-impact-of-nonmodifiable-risk-factors-in-orthopaedic-fracture-care-is-bundled-payment-feasible
#19
Siddharth A Mahure, Lorraine Hutzler, Richard S Yoon, Joseph A Bosco
OBJECTIVES: To determine whether bundled payments are feasible in the orthopaedic fracture setting, and the potential economic implications of this reimbursement structure. DESIGN: Prospective. SETTING: Multicenter. PATIENTS/PARTICIPANTS: Between 2004 and 2014, a total of 23,643 operatively treated patients with fracture and 544,067 patients with total joint arthroplasty (TJA) were identified using the New York State Statewide Planning and Research Cooperative System database...
March 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28202321/anxiety-and-depression-among-sexual-minority-women-and-men-in-sweden-is-the-risk-equally-spread-within-the-sexual-minority-population
#20
Charlotte Björkenstam, Emma Björkenstam, Gunnar Andersson, Susan Cochran, Kyriaki Kosidou
INTRODUCTION: Sexual minority individuals have a higher risk of anxiety and depression compared with heterosexuals. However, whether the higher risk is spread equally across the sexual minority population is not clear. AIM: To investigate the association between sexual orientation and self-reported current anxiety and a history of diagnosis of depression, paying particular attention to possible subgroup differences in risks within the sexual minority population, stratified by sex and to examine participants' history of medical care for anxiety disorders and depression...
February 12, 2017: Journal of Sexual Medicine
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