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https://www.readbyqxmd.com/read/29029236/first-in-human-experience-with-complete-integration-of-neuromodulation-device-within-a-customized-cranial-implant
#1
Chad R Gordon, Gabriel F Santiago, Judy Huang, Gregory K Bergey, Shuya Liu, Mehran Armand, Henry Brem, William S Anderson
BACKGROUND: Neuromodulation devices have the potential to transform modern day treatments for patients with medicine-resistant neurological disease. For instance, the NeuroPace System (NeuroPace Inc, Mountain View, California) is a Food and Drug Administration (FDA)-approved device developed for closed-loop direct brain neurostimulation in the setting of drug-resistant focal epilepsy. However, current methods require placement either above or below the skull in nonanatomic locations. This type of positioning has several drawbacks including visible deformities and scalp pressure from underneath leading to eventual wound healing difficulties, micromotion of hardware with infection, and extrusion leading to premature explantation...
October 6, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29027074/uptake-of-radium-223-dichloride-and-early-18-f-naf-pet-response-are-driven-by-baseline-18-f-naf-parameters-a-pilot-study-in-castration-resistant-prostate-cancer-patients
#2
Arthur Letellier, Alison C Johnson, Nicolas How Kit, Jean-François Savigny, Alain Batalla, Jean-Jacques Parienti, Nicolas Aide
PURPOSE: The purpose of this study is to identify predictive factors on baseline [(18)F]NaF positron emission tomography (PET)/computed tomography (CT) of early response to radium-223 dichloride after 3 cycles of treatment in metastatic castration-resistant prostate cancer patients. PROCEDURES: Analysis of 152 metastases was performed in six consecutive patients who underwent [(18)F]NaF PET/CT at baseline and for early monitoring after 3 cycles of radium-223 dichloride...
October 12, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29026962/abdominal-contouring-outcomes-in-class-iii-obesity-analysis-of-the-acs-nsqip-database
#3
Husain T AlQattan, Leela S Mundra, Gustavo A Rubio, Seth R Thaller
BACKGROUND: Obesity may increase the risk of complications following abdominal contouring. The aim of this study is to evaluate panniculectomy outcomes in patients with class III obesity (BMI > 40 kg/m(2)). METHODS: The American College of Surgeon's National Surgical Quality Improvement Program ACS-NSQIP (2010-2014) was used to identify patients who underwent panniculectomy. Class III obesity patients were identified. Demographics, comorbidities and postoperative outcomes were evaluated...
October 12, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29026936/a-comparative-study-of-full-thickness-blepharotomy-versus-transconjunctival-eyelid-lengthening-in-the-correction-of-upper-eyelid-retraction-in-graves-orbitopathy
#4
Allan C Pieroni Gonçalves, Thiago Nogueira, Ana Carolina Arato Gonçalves, Luzia Diegues Silva, Suzana Matayoshi, Mário L R Monteiro
BACKGROUND: The study was designed to compare the outcome of full-thickness blepharotomy and transconjunctival eyelid lengthening in the correction of upper eyelid retraction (UER) in patients with Graves' orbitopathy (GO). METHODS: This is a prospective randomized interventional study. Following ophthalmic examination, determination of the ocular surface disease index (OSDI) and photography, 27 patients with UER were randomly assigned to either graded full-thickness blepharotomy (G1) or transconjunctival Müller muscle recession and graded disinsertion of the levator palpebrae superioris muscle (G2)...
October 12, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29026830/treatment-of-constriction-bands-of-limbs-by-fat-injection-an-additional-modality
#5
Mahendra Daya
BACKGROUND: Constriction bands in the majority of cases presents as a contour deformity. The gold standard of treatment is a single-stage constriction ring excision and serial Z-plasty. The expense is unsightly scarring. We present case reports of deformity correction by serial fat injections. METHODS AND PARTICIPANTS: Three case studies of children in whom this modality was used in limbs to correct the deformity are presented. RESULTS: Two participants showed a good correction of the deformity and in a single-case treatment failed requiring excision and serial Z-plasty for correction...
August 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29026828/objective-outcomes-of-minimally-invasive-temporalis-tendon-transfer-for-prolonged-complete-facial-paralysis
#6
Michal Brichacek, Babar Sultan, Kofi D Boahene, Lisa Ishii, Patrick J Byrne
OBJECTIVES: We describe an approach to reanimation of complete, prolonged facial paralysis using minimally invasive temporalis tendon transfer (MIT3) by the melolabial or transoral approach. Objective outcome measures are evaluated based on symmetry, and grading of preoperative/post-operative results and the scar at the melolabial fold. STUDY DESIGN: Retrospective cohort study. METHODS: Twenty-five patients undergoing the MIT3 technique were studied...
August 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29026194/the-equivalent-internal-orientation-and-position-noise-for-contour-integration
#7
Alex S Baldwin, Minnie Fu, Reza Farivar, Robert F Hess
Contour integration is the joining-up of local responses to parts of a contour into a continuous percept. In typical studies observers detect contours formed of discrete wavelets, presented against a background of random wavelets. This measures performance for detecting contours in the limiting external noise that background provides. Our novel task measures contour integration without requiring any background noise. This allowed us to perform noise-masking experiments using orientation and position noise. From these we measure the equivalent internal noise for contour integration...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025052/ultrasound-double-contour-sign-and-gout
#8
Y-H Chen, C-C Lu, C-C Chang
No abstract text is available yet for this article.
July 21, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29024489/a-novel-combination-regimen-with-intense-focused-ultrasound-and-pressure-and-dose-controlled-transcutaneous-pneumatic-injection-of-hypertonic-glucose-solution-for-lifting-and-tightening-of-the-aging-face
#9
Hyuck Hoon Kwon, Sun Chul Choi, Kyung-Hoon Park, Jae Yoon Jung
BACKGROUND: Intense focused ultrasound (IFUS) has demonstrated moderate efficacy for facial laxity of the aging face. Pressure- and dose-controlled transcutaneous pneumatic injections of hypertonic glucose solution (TPIG) are a minimally invasive way to deliver solution into the skin for therapeutic purposes. Recently, its application around temporal areas is known to exert early-onset lifting effects with facial contour rejuvenation. AIMS: We sought to evaluate the safety and efficacy of this novel combination regimen with IFUS and TPIG for lifting and tightening of aging face...
October 12, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29023622/osseous-healing-around-immediate-implants-placed-using-contour-augmentation-a-prospective-case-series
#10
Bradley S DeGroot, Cristina C Villar, Brian L Mealey, Michael P Mills, Thomas J Prihoda, Guy Huynh-Ba
The purpose of this study was to prospectively evaluate the dimensional bone changes around implants placed immediately with buccal contour augmentation. Patients with hopeless maxillary anterior teeth were treated with extraction, immediate implant placement, and simultaneous buccal contour augmentation. Hard tissue measurements were recorded at the time of implant placement and after 3 months of healing. All implants (N = 18) successfully osseointegrated with a mean buccal bone thickness of 2.94 ± 0.21 mm (mean ± SE) at the implant platform...
November 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29023617/socket-shield-technique-for-implant-placement-in-the-esthetic-zone-a-case-report
#11
Matthias Petsch, Benedikt Spies, Ralf-Joachim Kohal
Improvements in implant design, placement protocols, and sequences for reconstruction in the anterior region have enabled clinicians to provide their patients with esthetically acceptable results. Yet from a clinical standpoint, the predictable preservation of the peri-implant soft tissue remains challenging and tissue grafting is often necessary to compensate for ridge contour changes in postextraction sites. In animal and clinical studies, the socket shield technique has shown its potential to prevent resorption of buccal tissues...
November 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29023610/the-management-of-peri-implant-mucosa-deficiencies-in-esthetic-sites-case-report-of-a-combined-surgical-prosthetic-approach
#12
Karolina Jurczyk, Urs C Belser, Anton Sculean
In cases of single missing teeth, implant rehabilitation is generally the preferred treatment option. However, obtaining pleasing esthetic results in the anterior maxillary region and maintaining or rebuilding peri-implant papillae remain challenging tasks. The loss of papillae may cause not just functional but also phonetic and esthetic problems. There is scarce information on the reliability of surgical approaches concerning the peri-implant papilla. The purpose of this case report is to present a modified prosthetic-surgical technique to enhance the convex facial contour of the peri-implant mucosa and volume and height of papillary tissue in an esthetically highly demanding patient...
November 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29022811/the-inferior-dermal-flap-technique-for-trans-male-chest-contouring
#13
C Wright, K Williams, G Dabritz
No abstract text is available yet for this article.
September 13, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29021615/a-new-pedicled-internal-mammary-osteomyocutaneous-chimeric-flap-pimoc-for-salvage-head-and-neck-reconstruction-anatomic-study-and-clinical-application
#14
Guilherme C Barreiro, Chelsea C Snider, Flavio H F Galvão, Rachel R Baptista, Kiril E Kasai, Daniel M Dos Anjos, Marcus C Ferreira
Well-vascularized composite tissue offers improved outcomes for complex head and neck reconstruction. Patients with vessel-depleted necks and failed reconstructions require alternative reconstructive options. We describe a pedicled internal mammary artery osteomyocutaneous chimeric flap (PIMOC) for salvage head and neck reconstruction. Bilateral dissections of 35 fresh cadavers were performed to study individual tissue components and vascular pedicles to develop the PIMOC technique. The flap was then utilized in a series of patients with vessel-depleted neck anatomy...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29020753/erratum-to-morphometric-analysis-of-passiflora-leaves-the-relationship-between-landmarks-of-the-vasculature-and-elliptical-fourier-descriptors-of-the-blade
#15
Daniel H Chitwood, Wagner C Otoni
Background: Leaf shape among Passiflora species is spectacularly diverse. Underlying this diversity in leaf shape are profound changes in the patterning of the primary vasculature and laminar outgrowth. Each of these aspects of leaf morphology-vasculature and blade-provides different insights into leaf patterning. Results: Here, we morphometrically analyze >3300 leaves from 40 different Passiflora species collected sequentially across the vine. Each leaf is measured in two different ways: using 1) 15 homologous Procrustes-adjusted landmarks of the vasculature, sinuses, and lobes; and 2) Elliptical Fourier Descriptors (EFDs), which quantify the outline of the leaf...
October 1, 2017: GigaScience
https://www.readbyqxmd.com/read/29019166/buckling-of-elastic-filaments-by-discrete-magnetic-moments
#16
Horst-Holger Boltz, Stefan Klumpp
We study the buckling of an idealized, semiflexible filament along whose contour magnetic moments are placed. We give analytic expressions for the critical stiffness of the filament below which it buckles due to the magnetic compression. For this, we consider various scenarios of the attachment of the magnetic particles to the filament. One possible application for this model are the magnetosome chains of magnetotactic bacteria. An estimate of the critical bending stiffness indicates that buckling may occur within the range of biologically relevant parameters and suggests a role for the bending stiffness of the filament to stabilize the filament against buckling, which would compromise the functional relevance of the bending stiffness of the used filament...
October 2017: European Physical Journal. E, Soft Matter
https://www.readbyqxmd.com/read/29019109/automatic-delineation-of-functional-lung-volumes-with-68-ga-ventilation-perfusion-pet-ct
#17
Pierre-Yves Le Roux, Shankar Siva, Jason Callahan, Yannis Claudic, David Bourhis, Daniel P Steinfort, Rodney J Hicks, Michael S Hofman
BACKGROUND: Functional volumes computed from (68)Ga-ventilation/perfusion (V/Q) PET/CT, which we have shown to correlate with pulmonary function test parameters (PFTs), have potential diagnostic utility in a variety of clinical applications, including radiotherapy planning. An automatic segmentation method would facilitate delineation of such volumes. The aim of this study was to develop an automated threshold-based approach to delineate functional volumes that best correlates with manual delineation...
October 10, 2017: EJNMMI Research
https://www.readbyqxmd.com/read/29018640/a-multi-classifier-system-for-automatic-mitosis-detection-in-breast-histopathology-images-using-deep-belief-networks
#18
K Sabeena Beevi, Madhu S Nair, G R Bindu
Mitotic count is an important diagnostic factor in breast cancer grading and prognosis. Detection of mitosis in breast histopathology images is very challenging mainly due to diffused intensities along object boundary and shape variation in different stages of mitosis. This paper demonstrates an accurate technique for detecting the mitotic cells in Hematoxyline and Eosin stained images by step by step refinement of segmentation and classification stages. Krill Herd Algorithm-based localized active contour model precisely segments cell nuclei from background stroma...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28994817/a-simple-robust-and-high-throughput-single-molecule-flow-stretching-assay-implementation-for-studying-transport-of-molecules-along-dna
#19
Kan Xiong, Paul C Blainey
We describe a simple, robust and high throughput single molecule flow-stretching assay for studying 1D diffusion of molecules along DNA. In this assay, glass coverslips are functionalized in a one-step reaction with silane-PEG-biotin. Flow cells are constructed by sandwiching an adhesive tape with pre-cut channels between a functionalized coverslip and a PDMS slab containing inlet and outlet holes. Multiple channels are integrated into one flow cell and the flow of reagents into each channel can be fully automated, which significantly increases the assay throughput and reduces hands-on time per assay...
October 1, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28993798/challenges-for-quality-assurance-of-target-volume-delineation-in-clinical-trials
#20
REVIEW
Amy Tien Yee Chang, Li Tee Tan, Simon Duke, Wai-Tong Ng
In recent years, new radiotherapy techniques have emerged that aim to improve treatment outcome and reduce toxicity. The standard method of evaluating such techniques is to conduct large scale multicenter clinical trials, often across continents. A major challenge for such trials is quality assurance to ensure consistency of treatment across all participating centers. Analyses from previous studies have shown that poor compliance and protocol violation have a significant adverse effect on treatment outcomes...
2017: Frontiers in Oncology
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