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"Hemispatial neglect"

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https://www.readbyqxmd.com/read/27903814/blink-associated-contralateral-eccentric-saccades-as-a-rare-sign-of-unilateral-brain-injury
#1
Ilaria Zivi, Eugenio Bertelli, Giacinta Bilotti, Ignazio Alessandro Clemente, Leopold Saltuari, Giuseppe Frazzitta
OBJECTIVE: To describe a rare sign of unilateral brain injury as a form of unwanted blink-associated contralateral eccentric saccades. METHODS: A 62-year-old patient who underwent an ischemic stroke affecting the entire right middle cerebral artery territory came to our attention 1 year after stroke, manifesting with transient contralateral conjugate gaze deviations associated with spontaneous blinking. We complemented the regular neurologic evaluation with brain MRI, study of evoked potentials, electroneurography of the facial nerve, and infrared video-oculoscopy...
November 30, 2016: Neurology
https://www.readbyqxmd.com/read/27801770/dehydration-status-is-associated-with-more-severe-hemispatial-neglect-after-stroke
#2
Mona N Bahouth, Zainab Bahrainwala, Argye E Hillis, Rebecca F Gottesman
BACKGROUND: Many stroke patients are clinically dehydrated at the time of hospital presentation, which could lead to an increase in blood viscosity and alteration in cerebral perfusion. Impaired cerebral perfusion can cause hemispheric dysfunction, which can be rapidly quantified with bedside tests of hemispatial neglect. We hypothesized that hospitalized patients with laboratory markers consistent with dehydration or a volume contracted state (VCS) would have more severe cerebral dysfunction defined by greater degree of neglect...
November 2016: Neurologist
https://www.readbyqxmd.com/read/27606267/the-effect-of-an-upper-limb-rehabilitation-robot-on-hemispatial-neglect-in-stroke-patients
#3
Yoon Sik Choi, Kyeong Woo Lee, Jong Hwa Lee, Sang Beom Kim, Gyu Tae Park, Sook Joung Lee
OBJECTIVE: To investigate the effectiveness of an upper limb rehabilitation robot therapy on hemispatial neglect in stroke patients. METHODS: Patients were randomly divided into an upper limb rehabilitation robot treatment group (robot group) and a control group. The patients in the robot group received left upper limb training using an upper limb rehabilitation robot. The patients sat on the right side of the robot, so that the monitor of the robot was located on the patients' left side...
August 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27543899/social-priming-of-hemispatial-neglect-affects-spatial-coding-evidence-from-the-simon-task
#4
Isabel Arend, Daniela Aisenberg, Avishai Henik
In the Simon effect (SE), choice reactions are fast if the location of the stimulus and the response correspond when stimulus location is task-irrelevant; therefore, the SE reflects the automatic processing of space. Priming of social concepts was found to affect automatic processing in the Stroop effect. We investigated whether spatial coding measured by the SE can be affected by the observer's mental state. We used two social priming manipulations of impairments: one involving spatial processing - hemispatial neglect (HN) and another involving color perception - achromatopsia (ACHM)...
October 2016: Consciousness and Cognition
https://www.readbyqxmd.com/read/27509209/the-impact-of-cortical-lesions-on-thalamo-cortical-network-dynamics-after-acute-ischaemic-stroke-a-combined-experimental-and-theoretical-study
#5
Joeri B G van Wijngaarden, Riccardo Zucca, Simon Finnigan, Paul F M J Verschure
The neocortex and thalamus provide a core substrate for perception, cognition, and action, and are interconnected through different direct and indirect pathways that maintain specific dynamics associated with functional states including wakefulness and sleep. It has been shown that a lack of excitation, or enhanced subcortical inhibition, can disrupt this system and drive thalamic nuclei into an attractor state of low-frequency bursting and further entrainment of thalamo-cortical circuits, also called thalamo-cortical dysrhythmia (TCD)...
August 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27494375/motor-versus-body-awareness-voxel-based-lesion-analysis-in-anosognosia-for-hemiplegia-and-somatoparaphrenia-following-right-hemisphere-stroke
#6
Valentina Moro, Simone Pernigo, Manos Tsakiris, Renato Avesani, Nicola M J Edelstyn, Paul M Jenkinson, Aikaterini Fotopoulou
Anosognosia for hemiplegia (AHP) is informative about the neurocognitive basis of motor awareness. However, it is frequently associated with concomitant symptoms, such as hemispatial neglect and disturbances in the sense of body ownership (DSO). Although double dissociations between these symptoms have been reported, there is ongoing debate about whether they are manifestations of independent abnormalities, or a single neurocognitive deficit. We aimed to investigate the specificity of lesions associated with AHP by surpassing four, existing methodological limitations: (a) recruit a relatively large sample of patients (total N = 70) in a multi-centre study; (b) identify lesions associated with AHP in grey and white matter using voxel-based methods; (c) take into account the duration of AHP and concomitant neglect symptoms; and (d) compare lesions against a control hemiplegic group, patients suffering from AHP and DSO, and a few, rare patients with selective DSO...
October 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/27313902/hemispatial-neglect-shows-that-before-is-left
#7
Mario Bonato, Arnaud Saj, Patrik Vuilleumier
Recent research has led to the hypothesis that events which unfold in time might be spatially represented in a left-to-right fashion, resembling writing direction. Here we studied fourteen right-hemisphere damaged patients, with or without neglect, a disorder of spatial awareness affecting contralesional (here left) space processing and representation. We reasoned that if the processing of time-ordered events is spatial in nature, it should be impaired in the presence of neglect and spared in its absence. Patients categorized events of a story as occurring before or after a central event, which acted as a temporal reference...
2016: Neural Plasticity
https://www.readbyqxmd.com/read/27277836/normalization-of-network-connectivity-in-hemispatial-neglect-recovery
#8
Lenny E Ramsey, Joshua S Siegel, Antonello Baldassarre, Nicholas V Metcalf, Kristina Zinn, Gordon L Shulman, Maurizio Corbetta
OBJECTIVE: We recently reported that spatial and nonspatial attention deficits in stroke patients with hemispatial neglect are correlated at 2 weeks postonset with widespread alterations of interhemispheric and intrahemispheric functional connectivity (FC) measured with resting-state functional magnetic resonance imaging across multiple brain networks. The mechanisms underlying neglect recovery are largely unknown. In this study, we test the hypothesis that recovery of hemispatial neglect correlates with a return of network connectivity toward a normal pattern, herein defined as "network normalization...
July 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27103056/semiology-of-neglect-an-update
#9
G Rode, C Pagliari, L Huchon, Y Rossetti, L Pisella
Hemispatial neglect is a common disabling condition following brain damage to the right hemisphere. Generally, it involves behavioral bias directed ipsilaterally to the damaged hemisphere and loss of spatial awareness for the contralesional side. In this syndrome, several clinical subtypes were identified. The objective of this article is to provide a nosological analysis of the recent data from the literature on the different subtypes of neglect (visual, auditory, somatosensory, motor, egocentric, allocentric and representational neglect), associated ipsilesional and contralesional productive manifestations and their anatomical lesion correlates...
April 18, 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/26889731/functional-cerebral-space-theory-towards-an-integration-of-theory-and-mechanisms-of-left-hemineglect-anosognosia-and-anosodiaphoria
#10
Andrew J Smith, Ransom W Campbell, Patti Kelly Harrison, David W Harrison
BACKGROUND: The current case study presents a 43 year old African American woman admitted to a Tertiary Care Rehabilitation unit at a major medical center for concerns over left-sided anesthesia and weakness. Head scans indicate a right middle cerebral arterial distribution infarct altering blood flow in temporal, parietal, and occipital regions in the right cerebral hemisphere. OBJECTIVE: Physician and therapist reports (i.e., speech and occupational therapists) referred the patient for a neuropsychological evaluation for concerns over the patient's capacity to recognize the severity of her deficits and self-care, with potential rule-outs indicated by the extant literature on right CVA for anosognosia, anosodiaphoria, and left hemibody/hemispace neglect...
2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/26873235/-higher-brain-dysfunction-in-mitochondrial-myopathy-encephalopathy-lactic-acidosis-and-stroke-like-episodes-melas
#11
REVIEW
Hiroo Ichikawa
Stroke-like episodes are one of the cardinal features of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), and occur in 84-99% of the patients. The affected areas detected on neuroimaging do not have classical vascular distribution, and involve predominantly the temporal, parietal and occipital lobes. Thus, the neurological symptoms including higher brain dysfunction correlate with this topographical distribution. In association with the occipital lobe involvement, the most frequent symptom is cortical blindness...
February 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/26786007/here-there-and-everywhere-higher-visual-function-and-the-dorsal-visual-stream
#12
REVIEW
Sarah Anne Cooper, Michael O'Sullivan
The dorsal visual stream, often referred to as the 'where' stream, represents the pathway taken by visual information from the primary visual cortex to the posterior parietal lobe and onwards. It partners the ventral or 'what' stream, the subject of a previous review and largely a temporal-based system. Here, we consider the dorsal stream disorders of perception (simultanagnosia, akinetopsia) along with their consequences on action (eg, optic ataxia and oculomotor apraxia, along with Balint's syndrome). The role of the dorsal stream in blindsight and hemispatial neglect is also considered...
June 2016: Practical Neurology
https://www.readbyqxmd.com/read/26679566/the-vestibular-system-balancing-more-than-just-the-body
#13
REVIEW
Christophe Lopez
PURPOSE OF REVIEW: The review presents a selection of recent studies in the field of vestibular neuroscience, including how vestibular stimulation modulates space and body perception. RECENT FINDINGS: Recent neuroimaging studies identified the operculo-insular/retroinsular cortex as the core vestibular cortex and showed how it is reorganized after vestibular dysfunctions. Subliminal galvanic vestibular stimulation (GVS) induces long-term reduction of hemispatial neglect and improves vertical perception in stroke patients, but the underlying mechanisms remain to be identified...
February 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/26378925/intra-and-inter-task-reliability-of-spatial-attention-measures-in-pseudoneglect
#14
Gemma Learmonth, Aodhan Gallagher, Jamie Gibson, Gregor Thut, Monika Harvey
Healthy young adults display a leftward asymmetry of spatial attention ("pseudoneglect") that has been measured with a wide range of different tasks. Yet at present there is a lack of systematic evidence that the tasks commonly used in research today are i) stable measures over time and ii) provide similar measures of spatial bias. Fifty right-handed young adults were tested on five tasks (manual line bisection, landmark, greyscales, gratingscales and lateralised visual detection) on two different days. All five tasks were found to be stable measures of bias over the two testing sessions, indicating that each is a reliable measure in itself...
2015: PloS One
https://www.readbyqxmd.com/read/26327028/tonic-and-phasic-alertness-training-enhances-executive-function-working-memory-and-skill-acquisition-in-older-adults
#15
Thomas Van Vleet, Joseph DeGutis, Michael Merzenich
The ability to sustain attention gradually declines with age, exacerbating normal decays in performance across multiple cognitive domains. In addition, poor sustained attention may impair efficient learning of new information and skills. Previous studies have shown that it is possible to enhance sustained attention in patients with severely impaired abilities, such as hemispatial neglect and traumatic brain injury, and that this generalizes to improvements in spatial attention and more global cognitive improvements (DeGutis & Van Vleet, 2010; Van Vleet et al...
2015: Journal of Vision
https://www.readbyqxmd.com/read/26307366/erratum-mirror-neuron-therapy-for-hemispatial-neglect-patients
#16
Wei Wang, Xin Zhang, Xiangtong Ji, Qian Ye, Wenli Chen, Jun Ni, Guangyu Shen, Bing Zhang, Ti-Fei Yuan, Chunlei Shan
No abstract text is available yet for this article.
2015: Scientific Reports
https://www.readbyqxmd.com/read/26283942/unveiling-residual-spontaneous-recovery-from-subtle-hemispatial-neglect-three-years-after-stroke
#17
Mario Bonato
A common and disabling consequence of stroke is the difficulty in processing contralesional space (i.e., hemispatial neglect). According to paper-and-pencil tests, neglect remits or stabilizes in severity within a few months after a brain injury. This arbitrary temporal limit, however, is at odds with neglect's well-known dependency on task-sensitivity. The present study tested the hypothesis that the putative early resolution of neglect might be due to the insensitivity of testing methods rather than to the lack of spontaneous recovery at later stages...
2015: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/26279198/internally-represented-space-and-its-mirror-reversed-image-of-the-visuospatial-representation-a-possible-association
#18
Masahiko Sumitani, Masaya Misaki, Shin-ichiro Kumagaya, Arito Yozu, Yuko Otake, Michihiro Osumi, Satoru Miyauchi
The cognitive capacity for number representation is thought to be a functional isomorphism of space representation. Numbers are represented in a left-to-right-oriented mental number line and hemispatial neglect patients consistently demonstrate rightward midline shift of visuospace, the internal space and number representation. However, patients with pathologic pain in one limb showed a negative correlation between midline shift of the visuospace and number representation. The purpose of the present study is to ascertain whether such dissociation in accessing space and number representation is observed in another neuropathic pain condition, and then to propose a theoretical model regarding an intimate relationship between visuospace and internal space representations...
October 2015: Medical Hypotheses
https://www.readbyqxmd.com/read/26269642/influences-of-long-term-memory-guided-attention-and-stimulus-guided-attention-on-visuospatial-representations-within-human-intraparietal-sulcus
#19
Maya L Rosen, Chantal E Stern, Samantha W Michalka, Kathryn J Devaney, David C Somers
UNLABELLED: Human parietal cortex plays a central role in encoding visuospatial information and multiple visual maps exist within the intraparietal sulcus (IPS), with each hemisphere symmetrically representing contralateral visual space. Two forms of hemispheric asymmetries have been identified in parietal cortex ventrolateral to visuotopic IPS. Key attentional processes are localized to right lateral parietal cortex in the temporoparietal junction and long-term memory (LTM) retrieval processes are localized to the left lateral parietal cortex in the angular gyrus...
August 12, 2015: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/26209293/the-time-dependent-and-persistent-effects-of-amphetamine-treatment-upon-recovery-from-hemispatial-neglect-in-rats
#20
Miranda M Brenneman, Michael J Hylin, James V Corwin
Neglect is a neuropsychological disorder characterized by the failure to report or respond to stimuli presented to the side of the body opposite a brain lesion and occurs in approximately 40% of right hemisphere strokes. The need for effective therapies to treat neglect in humans has led to the development of a rodent model. Unilateral destruction of medial agranular cortex (AGm), which is part of a cortical network for directed attention, produces severe multimodal neglect with deficits similar to those seen in humans...
October 15, 2015: Behavioural Brain Research
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