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Cerebral Aneurysms

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https://www.readbyqxmd.com/read/28805753/-prognostic-significance-of-leukocyte-count-in-the-venous-blood-in-the-acute-stage-of-cerebral-aneurism-rupture
#1
A A Kalinkin, S S Petrikov, L T Khamidova, V V Krylov
AIM: To determine a prognostic role of leukocyte count in the venous blood in the acute stage of cerebral aneurysm (CA) rupture. MATERIAL AND METHODS: Fifty-one patients with CA rupture, aged from 20 to 65 years, hospitalized in the first 72 h over the period from 01.10.12 to 01.02.16 were examined. The severity of disease and anatomical form of hemorrhage was corresponded to III-IV degree on the W. Hunt - R. Hess scale and Fisher scale. All patients underwent surgery...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28803174/intraoperative-vascular-neuromonitoring-in-patients-with-subarachnoid-hemorrhage-a-pilot-study-using-combined-laser-doppler-spectrophotometry
#2
Emilija Schmitz, Barbara Bischoff, Dennis Wolf, Hubert Schmitt, Ilker Y Eyupoglu, Karl Roessler, Michael Buchfelder, Björn Sommer
OBJECTIVE: Intraoperative monitoring of cerebral microcirculation in patients with subarachnoid hemorrhage (SAH) may predict the postoperative neurological outcome. In this pilot study, we examined the value of a novel non-invasive real-time measurement technique to detect changes in local microcirculation. METHODS: We used the laser-Doppler spectrophotometry system "Oxygen-to-see(O2C)" in 14 patients with SAH Hunt & Hess grade 2 to 5, who underwent microsurgical clipping of cerebral aneurysms...
August 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28802549/diffuse-renal-cortical-hemorrhage-in-the-setting-of-subcapsular-hematoma-diagnosis-and-treatment-with-embolization
#3
Marta Burrel, Marta Barrufet, Maria Carme Sebastia, Jonathan Joudanin, Laura Buñesch, Patricia Bermudez, Jordi Blasco, Rosa Gilabert
PURPOSE: To describe radiologic findings, embolization technique, and clinical outcomes in patients with renal subcapsular hematoma and diffuse cortical hemorrhage. MATERIALS AND METHODS: Ten patients with renal subcapsular hematoma and diffuse cortical hemorrhage were reviewed. Nine of the 10 had undergone procedures (nephrostomy, n = 4; biopsy, n = 4; embolization of a cerebral aneurysm, n = 1) and 1 patient was receiving oral anticoagulation. Computed tomography (CT), angiography, and embolization of bleeding sites were performed in all patients...
August 9, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28799316/mirror-aneurysm-with-right-frontal-ich-in-a-patient-with-osteogenesis-imperfecta
#4
Vijay Sardana, Sumit Kamble, Sunil K Sharma, Dilip Maheshwari, Bharat Bhushan
Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders that occur owing to the abnormalities in type 1 collagen, and is characterized by increased bone fragility and other extraskeletal manifestations. OI may be associated with vascular complications such as aortic and cervical artery dissection, carotid cavernous fistula, and coronary artery aneurysms but unlike other connective tissue diseases, the cerebrovascular system is less frequently involved. We report rare case of 50 year female patient who was diagnosed with OI following right frontal haemorrhage secondary to a ruptured middle cerebral artery mirror aneurysm...
August 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28796397/clinical-evaluation-of-time-of-flight-mr-angiography-with-sparse-undersampling-and-iterative-reconstruction-for-cerebral-aneurysms
#5
Yasutaka Fushimi, Tomohisa Okada, Takayuki Kikuchi, Akira Yamamoto, Tsutomu Okada, Takayuki Yamamoto, Michaela Schmidt, Kazumichi Yoshida, Susumu Miyamoto, Kaori Togashi
Compressed sensing (CS) MRI has just been introduced to research areas as an innovative approach to accelerate MRI. CS is expected to achieve higher k-space undersampling by exploiting the underlying sparsity in an appropriate transform domain. MR angiography (MRA) provides high spatial resolution information on arteries; however, a relatively long acquisition time is necessary to cover a wide volume. Reduction of acquisition time by CS for time-of-flight (TOF) MR angiography (Sparse-TOF) is beneficial in clinical examinations; therefore, the clinical validity of Sparse-TOF needs to be investigated...
August 10, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28790215/-a-case-of-ruptured-distal-anterior-choroidal-artery-aneurysm-associated-with-a-twig-like-middle-cerebral-artery-treated-with-single-stage-aneurysm-clipping-and-sta-mca-double-anastomoses-in-the-acute-phase
#6
Toshimoto Seno, Kanehisa Kohno, Hideo Tanaka, Shinji Iwata, Shinya Fukumoto, Haruhisa Ichikawa, Noriyuki Fumoto, Akihiro Inoue, Saya Ozaki, Yawara Nakamura, Shohei Kohno, Shiro Ohue
We report the case of a patient who has progressed well over 5 years following single-stage aneurysm clipping and superficial temporal artery-middle cerebral artery(STA-MCA)double anastomoses in the acute phase, for a ruptured distal anterior choroidal artery(AChA)aneurysm accompanied by a twig-like MCA. The patient was a 49-year-old female who developed a sudden severe headache and disturbance of consciousness due to subarachnoid hemorrhage and intraventricular hemorrhage(IVH). Cerebral angiography showed a right twig-like MCA associated with an abnormal vascular network and a ruptured aneurysm in the distal AChA...
August 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28782688/urine-f2-isoprostanes-concentration-as-a-poor-prognostic-factor-after-subarachnoid-haemorrhage
#7
Karol Wiśniewski, Michał Bieńkowski, Bartłomiej Tomasik, Marcin Braun, Ernest J Bobeff, Paweł P Liberski, Dariusz J Jaskólski
BACKGROUND: The role of isoprostanes in cerebral vasospasm (CVS) after aneurysmal subarachnoid haemorrhage (aSAH) has remained controversial. Recent studies have suggested that the level of isoprostanes in cerebral spinal fluid could play a role in aSAH patients outcomes. We have measured their concentration in urine as collection is simple and non-invasive. Due to their biological mechanism of action, it is essential to identify their role in aSAH patients. METHODS: A prospective analysis of clinical data and urine samples of 20 patients with aSAH who underwent microsurgical clipping of the aneurysmal neck between May 2016 and January 2017...
August 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28781921/ruptured-mycotic-aneurysms-report-and-outcomes-of-two-surgically-managed-patients
#8
Aleena Khan, Muhammad Waqas, Waseem M Nizamani, Muhammad E Bari
BACKGROUND: Mycotic aneurysm is a rare potentially life-threatening complication of infective endocarditis (IE). Little data is available on the management and outcomes of ruptured mycotic aneurysms with large intracerebral hematoma. Few cases have been described on the management of mycotic aneurysm in the presence of life-threatening hematoma and mass effect. CASE DESCRIPTION: We are presenting two cases of ruptured mycotic aneurysm with intracerebral hematoma and impending brain herniation...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28777036/endovascular-treatment-of-a-large-ruptured-middle-cerebral-artery-bifurcation-aneurysm-in-a-5-week-old-infant-case-report
#9
Kristopher A Lyon, Eliel N Arrey, Ali S Haider, Dhruve S Jeevan, Ethan A Benardete
Ruptured intracranial aneurysms are extremely rare in infants. The optimal treatment strategy is not well established. Both microsurgical and endovascular techniques and strategies have been tried, and in the literature there is a significant variability in outcome. The authors report the presentation and successful endovascular treatment of a large, ruptured, middle cerebral artery bifurcation aneurysm in a 5-week-old girl, one of only a few reported in the literature. Clinical and radiological findings at follow-up are also presented...
August 4, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28777022/association-of-cystathionine-beta-synthase-polymorphisms-and-aneurysmal-subarachnoid-hemorrhage
#10
Philipp Hendrix, Paul M Foreman, Mark R Harrigan, Winfield S Fisher, Nilesh A Vyas, Robert H Lipsky, Mingkuan Lin, Beverly C Walters, R Shane Tubbs, Mohammadali M Shoja, Jean-Francois Pittet, Mali Mathru, Christoph J Griessenauer
OBJECTIVE Cystathionine β-synthase (CBS) is involved in homocysteine and hydrogen sulfide (H2S) metabolism. Both products have been implicated in the pathophysiology of cerebrovascular diseases. The impact of CBS polymorphisms on aneurysmal subarachnoid hemorrhage (aSAH) and its clinical sequelae is poorly understood. METHODS Blood samples from all patients enrolled in the CARAS (Cerebral Aneurysm Renin Angiotensin System) study were used for genetic evaluation. The CARAS study prospectively enrolled aSAH patients at 2 academic institutions in the United States from 2012 to 2015...
August 4, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28774792/macrophage-imaging-of-cerebral-aneurysms-with-ferumoxytol-an-exploratory-study-in-an-animal-model-and-in-patients
#11
Tomohiro Aoki, Makoto Saito, Hirokazu Koseki, Keiichi Tsuji, Atsushi Tsuji, Kiyoshi Murata, Hidetoshi Kasuya, Akio Morita, Shuh Narumiya, Kazuhiko Nozaki
OBJECTIVE: The purpose of this study is to assess the validity and feasibility of macrophage imaging using an ultrasmall superparamagnetic iron oxide nanoparticle, ferumoxytol, in the cerebral aneurysmal wall in an animal model and in humans. MATERIALS AND METHODS: Engulfment of ferumoxytol by primary culture of macrophages and RAW264.7 cells was assessed. Uptake of ferumoxytol was evaluated histologically in a cerebral aneurysmal model in rats. In an exploratory clinical study of magnetic resonance macrophage imaging, 17 unruptured aneurysms in 17 patients were imaged using thin-slice gapless magnetic resonance images of 2D-gradient-recalled echo (2D-GRE) and 3D-T1-fast-spin echo sequences on day 0 and of the same sequences with infusion of ferumoxytol 24 hours after the first imaging...
July 31, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28774294/temperature-variability-in-the-day-night-cycle-is-associated-with-further-intracranial-pressure-during-therapeutic-hypothermia
#12
Adriano Barreto Nogueira, Eva Annen, Oliver Boss, Faraneh Farokhzad, Christopher Sikorski, Emanuela Keller
BACKGROUND: To assess whether circadian patterns of temperature correlate with further values of intracranial pressure (ICP) in severe brain injury treated with hypothermia. METHODS: We retrospectively analyzed temperature values in subarachnoid hemorrhage patients treated with hypothermia by endovascular cooling. The circadian patterns of temperature were correlated with the mean ICP across the following day (ICP24). RESULTS: We analyzed data from 17 days of monitoring of three subarachnoid hemorrhage patients that underwent aneurysm coiling, sedation and hypothermia due to refractory intracranial hypertension and/or cerebral vasospasm...
August 3, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28770205/fatal-mycotic-aneurysm-of-the-basilar-artery-caused-by-aspergillus-fumigatus-in-a-patient-with-pituitary-adenoma-and-meningitis
#13
Martin Winterholler, Roland Coras, Walter Geißdörfer, Rudolf Rammensee, Philipp Gölitz, Christian Bogdan, Roland Lang
Fungal infections of the central nervous system (CNS) frequently occur in immunosuppressed patients. Here, we describe the case of an immunocompetent 64-year-old man who presented with diplopia, right-sided hemiparesis, and a mild headache after cleaning and replacing nesting boxes of wild birds during the preceding months. Lumbar puncture revealed pleocytosis, elevated protein, and lactate levels in the cerebrospinal fluid (CSF). Initial imaging showed ischemia in the left thalamus and an enlargement of the sellar region...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28769872/intracranial-arterial-dolichoectasia
#14
REVIEW
Victor J Del Brutto, Jorge G Ortiz, José Biller
An increased diameter (ectasis) and/or long and tortuous course (dolichosis) of at least one cerebral artery define intracranial arterial dolichoectasia (IADE). IADE could be detected incidentally or may give rise to an array of neurological complications including ischemic stroke, intracranial hemorrhage, or compression of surrounding neural structures. The basilar artery is preferentially affected and has been studied in more detail, mainly due to the presence of accepted diagnostic criteria proposed by Smoker and colleagues in 1986 (1)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28768819/rabbit-aneurysm-models-mimic-histologic-wall-types-identified-in-human-intracranial-aneurysms
#15
Shunli Wang, Daying Dai, Praveen Kolumam Parameswaran, Ramanathan Kadirvel, Yong-Hong Ding, Anne M Robertson, David F Kallmes
BACKGROUND: Semiquantitative scales correlate histopathologic findings in the walls of human aneurysms with rupture status. OBJECTIVE: To apply a semiquantitative scale to the rabbit elastase-induced aneurysm model to determine whether rabbit histologic types mimic the full range of histologic subtypes of humans. MATERIALS AND METHODS: Twenty-seven elastase-induced female rabbit aneurysms were studied, harvested at 2 weeks (n=5) and 12 weeks (n=22)...
August 2, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28768799/microrna-changes-in-cerebrospinal-fluid-after-subarachnoid-hemorrhage
#16
Søren Bache, Rune Rasmussen, Maria Rossing, Finn Pedersen Laigaard, Finn Cilius Nielsen, Kirsten Møller
BACKGROUND AND PURPOSE: Delayed cerebral ischemia (DCI) accounts for a major part of the morbidity and mortality after aneurysmal subarachnoid hemorrhage (SAH). MicroRNAs (miRNAs) are pathophysiologically involved in acute cerebral ischemia. This study compared miRNA profiles in cerebrospinal fluid from neurologically healthy patients, as well as SAH patients with and without subsequent development of DCI. METHODS: In a prospective case-control study of SAH patients treated with external ventricular drainage and neurologically healthy patients, miRNA profiles in cerebrospinal fluid were screened and validated using 2 different high-throughput real-time quantification polymerase chain reaction techniques...
August 2, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28767530/the-use-of-ultrabrief-left-unilateral-electroconvulsive-therapy-in-a-patient-with-cerebral-aneurysms-and-right-sided-encephalomalacia-and-stroke-a-case-report
#17
Ahmed Z Elmaadawi, Shady S Mashaly, Suhayl Nasr
No abstract text is available yet for this article.
August 1, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28765030/relationship-of-a1-segment-hypoplasia-to-the-radiological-and-clinical-outcomes-of-surgical-clipping-anterior-communicating-artery-aneurysm
#18
Fan Yang, Hao Li, Jun Wu, Maogui Li, Xin Chen, Pengjun Jiang, Zhengsong Li, Yong Cao, Shuo Wang
OBJECTIVE: This study aims to assess whether the A1 segment hypoplasia is a risk factor for unfavorable radiological and clinical outcomes of surgical clipping anterior communicating artery (ACoA) aneurysm. METHODS: We retrospectively reviewed 251 patients with ACoA aneurysm who underwent surgical clipping in Beijing Tiantan Hospital between September 2011 and September 2016. Their clinical and radiologic features, as well as clinical outcomes were reviewed. In addition, univariate and multivariate logistic regression analysis was performed to identify independent risk factors for the postoperative infarction and unfavorable clinical outcomes of surgical clipping ACoA aneurysm...
July 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28762878/long-acting-statin-for-aneurysmal-subarachnoid-hemorrhage-a-randomized-double-blind-placebo-controlled-trial
#19
Masato Naraoka, Naoya Matsuda, Norihito Shimamura, Kenichiro Asano, Kenichi Akasaka, Atsuhito Takemura, Seiko Hasegawa, Hiroki Ohkuma
Statins have pleiotropic effects that are considered beneficial in preventing cerebral vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage (aSAH). Many studies using statins have been performed but failed to show remarkable effects. We hypothesized that a long-acting statin would be more effective, due to a longer half-life and stronger pleiotropic effects. Patients with aSAH were randomly assigned to a pitavastatin group (4 mg daily; n = 54) and a placebo group ( n = 54) after repair of a ruptured aneurysm...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28762110/technique-for-rerouting-a-bridging-vein-that-hinders-the-anterior-interhemispheric-approach-a-technical-note
#20
Kenta Ohara, Tomohiro Inoue, Hideaki Ono, Satoshi Kiyofuji, Akira Tamura, Isamu Saito
BACKGROUND: The frontal bridging vein, which is the venous drainage route of the frontal cortex into the superior sagittal sinus (SSS), sometimes poses an obstacle in the anterior interhemispheric approach during surgery for anterior cerebral artery aneurysms. Although severe complications including venous infarction or edema due to damage to the bridging vein are well known, only a few reports have discussed how to avoid venous injury when we must sacrifice the bridging vein to obtain an appropriate surgical field...
August 1, 2017: Acta Neurochirurgica
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