Joaquim Bellmunt Molins, Jesús García-Donas Jiménez, Begoña P Valderrama, Juan Antonio Virizuela Echaburu, Susana Hernando-Polo, Miguel Ángel Climent Durán, José Carlos Villa-Guzmán, José Ángel Arranz Arija, Mar Llorente Ostiategui, Nuria Laínez Milagro, Aránzazu González-Del-Alba, Begoña Mellado González, Enrique Gallardo Díaz, Daniel Castellano Gauna, Montserrat Domènech Santasusana, Urbano Anido Herranz, Xavier García Del Muro Solans, José Luis Pérez-Gracia, Javier Puente Vázquez, Rafael Morales-Barrera, Albert Font Pous
INTRODUCTION: The MAJA study compared vinflunine (VFL) plus best supportive care (BSC) maintenance therapy versus BSC alone in advanced urothelial carcinoma responsive to first-line chemotherapy. The primary end point of progression-free survival was achieved. We present the final overall survival (OS) and long-term follow-up safety analyses. PATIENTS AND METHODS: Patients were enrolled, and a subsequent post hoc analysis was performed on the basis of radiologic response or stabilization to first-line cisplatin/gemcitabine (CG) chemotherapy (4-6 cycles), according to Response Evaluation Criteria in Solid Tumors (RECIST)...
May 11, 2020: Clinical Genitourinary Cancer